OOIR: Observatory of International Research

Papers

(The median citation count of Transgenic Research is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Regulatory approaches for genome edited agricultural plants in select countries and jurisdictions around the world	64
Novel CRISPR/Cas applications in plants: from prime editing to chromosome engineering	42
Genome editing in cereal crops: an overview	41
Genome editing of polyploid crops: prospects, achievements and bottlenecks	35
CRISPR/Cas9-mediated targeted mutagenesis of TAS4 and MYBA7 loci in grapevine rootstock 101-14	32
Genome editing reagent delivery in plants	32
Targeted genome editing of plants and plant cells for biomanufacturing	28
Sustainable use of CRISPR/Cas in fish aquaculture: the biosafety perspective	24
Two efficient CRISPR/Cas9 systems for gene editing in soybean	18
Genome editing for resistance against plant pests and pathogens	18
A short overview of CRISPR-Cas technology and its application in viral disease control	17
Towards progressive regulatory approaches for agricultural applications of animal biotechnology	17
Transporters and transcription factors gene families involved in improving nitrogen use efficiency (NUE) and assimilation in rice (Oryza sativa L.)	16
The effect of Bt crops on soil invertebrates: a systematic review and quantitative meta-analysis	15
Functional analysis of rice OSCA genes overexpressed in the arabidopsis osca1 mutant due to drought and salt stresses	14
Stress-inducible Arabidopsis thaliana RD29A promoter constitutively drives Citrus sinensis APETALA1 and LEAFY expression and precocious flowering in transgenic Citrus spp.	14
Human immune reactivity of GGTA1/CMAH/A3GALT2 triple knockout Yucatan miniature pigs	14
Improved soybean transformation for efficient and high throughput transgenic production	13
Animal models for researching approaches to therapy of Duchenne muscular dystrophy	12
Xenotransplantation becoming reality	12
Removing politics from innovations that improve food security	12
Perspectives for epigenetic editing in crops	11
Novel transgenic mice with Cre-dependent co-expression of GFP and human ACE2: a safe tool for study of COVID-19 pathogenesis	10
Translocation from the chloroplast stroma into the thylakoid lumen allows expression of recombinant epidermal growth factor in transplastomic tobacco plants	10
Genome editing in fruit, ornamental, and industrial crops	10

Site-directed mutagenesis by biolistic transformation efficiently generates inheritable mutations in a targeted locus in soybean somatic embryos and transgene-free descendants in the T1 generation	9
Generation and characterization of a Myh6-driven Cre knockin mouse line	9
Analysis of expression characteristics of soybean leaf and root tissue-specific promoters in Arabidopsis and soybean	8
Uncoupling protein 1 knockout aggravates isoproterenol-induced acute myocardial ischemia via AMPK/mTOR/PPARα pathways in rats	8
Efficient knockout of the phytoene desaturase gene in a hybrid poplar (Populus alba × Populus glandulosa) using the CRISPR/Cas9 system with a single gRNA	8
Metabolic effects of agro-infiltration on N. benthamiana accessions	8
Pyramiding the antimicrobial PR1aCB and AATCB genes in ‘Tarocco’ blood orange (Citrus sinensis Osbeck) to enhance citrus canker resistance	8
Fusion to elastin-like polypeptide increases production of bioactive human IFN-γ in tobacco	8
Improving seed size, seed weight and seedling emergence in Camelina sativa by overexpressing the Atsob3-6 gene variant	8
Playing God and tampering with nature: popular labels for real concerns in synthetic biology	8
Association of myostatin deficiency with collagen related disease-umbilical hernia and tippy toe standing in pigs	8
Sequence modification on demand: search and replace tools for precise gene editing in plants	8
Dendrobium orchids carrying antisense ACC oxidase: small changes in flower morphology and a delay of bud abortion, flower senescence, and abscission of flowers	7
Target-specific mutations efficiency at multiple loci of CRISPR/Cas9 system using one sgRNA in soybean	7
Expression of barley oxalate oxidase confers resistance against Sclerotinia sclerotiorum in transgenic Brassica juncea cv Varuna	7
Improved production of GTKO/hCD55/hCD59 triple-gene-modified Diannan miniature pigs for xenotransplantation by recloning	7
Lessons learned from the introduction of genetically engineered crops: relevance to gene drive deployment in Africa	6
Fitness of F1 hybrids between 10 maternal wild soybean populations and transgenic soybean	6
Peri-natal growth retardation rate and fat mass accumulation in mice lacking Dip2A is dependent on the dietary composition	6
Improving the politics of biotechnological innovations in food security and other sustainable development goals	6
Reasons and riddance of Agrobacterium tumefaciens overgrowth in plant transformation	6
Mapping CRISPR-Cas9 public and commercial innovation using The Lens institutional toolkit	6
Overexpression of an aquaporin protein from Aspergillus glaucus confers salt tolerance in transgenic soybean	6
Proteome and physiological analyses reveal tobacco (Nicotiana tabacum) peroxidase 7 (POD 7) functions in responses to copper stress	6
Genetic engineering to improve essential and conditionally essential amino acids in maize: transporter engineering as a reference	6
Establishment of a Cre-rat resource for creating conditional and physiological relevant models of human diseases	6
Larval mosquito management and risk to aquatic ecosystems: A comparative approach including current tactics and gene-drive Anopheles techniques	5
Regulatory and policy considerations for the implementation of gene drive-modified mosquitoes to prevent malaria transmission	5
Identification of a novel laccase gene EuLAC1 and its potential resistance against Botrytis cinerea	5
Production of gene-edited pigs harboring orthologous human mutations via double cutting by CRISPR/Cas9 with long single-stranded DNAs as homology-directed repair templates by zygote injection	5
Production of a correctly assembled fibrinogen using transgenic silkworms	5
Transgenic poplar trees overexpressing AtGolS2, a stress-responsive galactinol synthase gene derived from Arabidopsis thaliana, improved drought tolerance in a confined field	5
Bioengineering potato plants to produce benzylglucosinolate for improved broad-spectrum pest and disease resistance	4
Evaluation of potential impacts on biodiversity of the salt-tolerant transgenic Eucalyptus camaldulensis harboring an RNA chaperonic RNA-Binding-Protein gene derived from common ice plant	4
Efficient deletion of LoxP-flanked selectable marker genes from the genome of transgenic pigs by an engineered Cre recombinase	4
Enhancing plant growth and biomass production by overexpression of GA20ox gene under control of a root preferential promoter	4
Mini review: genome and transcriptome editing using CRISPR-cas systems for haematological malignancy gene therapy	4
Generation of goats by nuclear transfer: a retrospective analysis of a commercial operation (1998–2010)	4
Ectopic expression of MYB repressor GmMYB3a improves drought tolerance and productivity of transgenic peanuts (Arachis hypogaea L.) under conditions of water deficit	4
Multilevel interactions between native and ectopic isoprenoid pathways affect global metabolism in rice	4
Sequencing of two transgenic early-flowering poplar lines confirmed vector-free single-locus T-DNA integration	3
MsSAMS, a cold stress-responsive gene, provides resistance to environmental stress in T2-generation transgenic plants	3
Transient expression of an scFvG8 antibody in plants and characterization of its effects on the virulence factor pthA of Xanthomonas citri subsp. citri	3
Esophageal striated muscle hypertrophy and muscle fiber type transformation in MSTN knockout pigs	3
Enhanced resistance to soybean cyst nematode in transgenic soybean via host-induced silencing of vital Heterodera glycines genes	3
Conversion of sheath blight susceptible indica and japonica rice cultivars into moderately resistant through expression of antifungal β-1,3-glucanase transgene from Trichoderma spp.	3
Elastin-like polypeptide and γ-zein fusions significantly increase recombinant protein accumulation in soybean seeds	3
A novel swine sex-linked marker and its application across different mammalian species	3
History of safe exposure and bioinformatic assessment of phosphomannose-isomerase (PMI) for allergenic risk	3
Improved lint yield under field conditions in cotton over-expressing transcription factors regulating fibre initiation	3

Overexpression of a multifunctional β-glucosidase gene from thermophilic archaeon Sulfolobus solfataricus in transgenic tobacco could facilitate glucose release and its use as a reporter	3
I-SceI and customized meganucleases-mediated genome editing in tomato and oilseed rape	3
Generation of C-to-G transversion in mouse embryos via CG editors	3
Effect of low VEGF on lung development and function	3
Timely gene detection assay and reliable screening of genetically engineered plants using an improved direct PCR-based technology	3
Methylation silencing and reactivation of exogenous genes in lentivirus-mediated transgenic mice	3
Direct and pleiotropic effects of the Masou Salmon Delta-5 Desaturase transgene in F1 channel catfish (Ictalurus punctatus)	3
Generation of a novel decay accelerating factor (DAF) knock-out rat model using clustered regularly-interspaced short palindromic repeats, (CRISPR)/associated protein 9 (Cas9), genome editing	3
The human EF1a promoter does not provide expression of the transgene in mice	2
Points to consider in seeking biosafety approval for research, testing, and environmental release of experimental genetically modified biocontrol products during research and development	2
The potential oncogenic effect of tissue-specific expression of JC polyoma T antigen in digestive epithelial cells	2
Preface: Genome editing in plants	2
Data challenges for future plant gene editing: expert opinion	2
Myostatin deficiency decreases cardiac extracellular matrix in pigs	2
Detection of ornamental transgenic fish by real-time PCR and fluorescence microscopy	2
Genetically modified maize impacts in Honduras: production and social issues	2
Generation and identification of endothelial-specific Hrh2 knockout mice	2
Mass spectrometric analysis of digesta does not improve the allergenicity assessment of GM crops	2
Delayed body development with reduced triglycerides levels in leptin transgenic pigs	2
Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis	2
Genetic quality: a complex issue for experimental study reproducibility	2
Degradation of transgenic Bacillus thuringiensis proteins in corn tissue in response to post-harvest management practices	2
Efficiency comparison of B6(Cg)-Tyrc−2j /J and C57BL/6NTac embryos as hosts for the generation of knockout mice	2
Kinetics of alpha-synuclein depletion in three brain regions following conditional pan-neuronal inactivation of the encoding gene (Snca) by tamoxifen-induced Cre-recombination in adult mice	2
Functional characterization of transcriptional activator gene SIARRI in tomato reveals its role in fruit growth and ripening	2
A comprehensive analysis of TDO2 expression in immune cells and characterization of immune cell phenotype in TDO2 knockout mice	2
Expression of Cre recombinase in chondrocytes causes abnormal craniofacial and skeletal development	2
Skeletal muscle phenotyping of Hippo gene-mutated mice reveals that Lats1 deletion increases the percentage of type I muscle fibers	2
Identification, purification, and pharmacological activity analysis of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAα1) expressed in transgenic rabbit mammary glands	2
Lactoferrin and its role in biotechnological strategies for plant defense against pathogens	2
Wheat α-gliadin and high-molecular-weight glutenin subunit accumulate in different storage compartments of transgenic soybean seed	2
Efficient identification of genomic insertions and flanking regions through whole-genome sequencing in three transgenic soybean events	2
Engineering a feedback inhibition-insensitive plant dihydrodipicolinate synthase to increase lysine content in Camelina sativa seeds	2