OOIR: Observatory of International Research

Papers

(The median citation count of Transgenic Research is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Regulatory approaches for genome edited agricultural plants in select countries and jurisdictions around the world	85
Novel CRISPR/Cas applications in plants: from prime editing to chromosome engineering	54
Genome editing in cereal crops: an overview	50
Genome editing of polyploid crops: prospects, achievements and bottlenecks	42
Genome editing reagent delivery in plants	36
Sustainable use of CRISPR/Cas in fish aquaculture: the biosafety perspective	35
Targeted genome editing of plants and plant cells for biomanufacturing	33
Genome editing for resistance against plant pests and pathogens	23
Two efficient CRISPR/Cas9 systems for gene editing in soybean	22
Transporters and transcription factors gene families involved in improving nitrogen use efficiency (NUE) and assimilation in rice (Oryza sativa L.)	19
Xenotransplantation becoming reality	19
A short overview of CRISPR-Cas technology and its application in viral disease control	19
Towards progressive regulatory approaches for agricultural applications of animal biotechnology	17
Stress-inducible Arabidopsis thaliana RD29A promoter constitutively drives Citrus sinensis APETALA1 and LEAFY expression and precocious flowering in transgenic Citrus spp.	16
Functional analysis of rice OSCA genes overexpressed in the arabidopsis osca1 mutant due to drought and salt stresses	15
Removing politics from innovations that improve food security	14
Perspectives for epigenetic editing in crops	14
Human immune reactivity of GGTA1/CMAH/A3GALT2 triple knockout Yucatan miniature pigs	14
Animal models for researching approaches to therapy of Duchenne muscular dystrophy	13
Expression of barley oxalate oxidase confers resistance against Sclerotinia sclerotiorum in transgenic Brassica juncea cv Varuna	12
Reasons and riddance of Agrobacterium tumefaciens overgrowth in plant transformation	12
Site-directed mutagenesis by biolistic transformation efficiently generates inheritable mutations in a targeted locus in soybean somatic embryos and transgene-free descendants in the T1 generation	12
Identification of a novel laccase gene EuLAC1 and its potential resistance against Botrytis cinerea	12
Genetic engineering to improve essential and conditionally essential amino acids in maize: transporter engineering as a reference	12
Playing God and tampering with nature: popular labels for real concerns in synthetic biology	11

Efficient knockout of the phytoene desaturase gene in a hybrid poplar (Populus alba × Populus glandulosa) using the CRISPR/Cas9 system with a single gRNA	11
Generation and characterization of a Myh6-driven Cre knockin mouse line	11
Novel transgenic mice with Cre-dependent co-expression of GFP and human ACE2: a safe tool for study of COVID-19 pathogenesis	11
Metabolic effects of agro-infiltration on N. benthamiana accessions	11
Genome editing in fruit, ornamental, and industrial crops	11
Regulatory and policy considerations for the implementation of gene drive-modified mosquitoes to prevent malaria transmission	10
Transgenic poplar trees overexpressing AtGolS2, a stress-responsive galactinol synthase gene derived from Arabidopsis thaliana, improved drought tolerance in a confined field	9
Target-specific mutations efficiency at multiple loci of CRISPR/Cas9 system using one sgRNA in soybean	9
Uncoupling protein 1 knockout aggravates isoproterenol-induced acute myocardial ischemia via AMPK/mTOR/PPARα pathways in rats	9
Proteome and physiological analyses reveal tobacco (Nicotiana tabacum) peroxidase 7 (POD 7) functions in responses to copper stress	9
Pyramiding the antimicrobial PR1aCB and AATCB genes in ‘Tarocco’ blood orange (Citrus sinensis Osbeck) to enhance citrus canker resistance	9
Fitness of F1 hybrids between 10 maternal wild soybean populations and transgenic soybean	9
Mapping CRISPR-Cas9 public and commercial innovation using The Lens institutional toolkit	8
Association of myostatin deficiency with collagen related disease-umbilical hernia and tippy toe standing in pigs	8
Establishment of a Cre-rat resource for creating conditional and physiological relevant models of human diseases	8
Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis	8
I-SceI and customized meganucleases-mediated genome editing in tomato and oilseed rape	8
Analysis of expression characteristics of soybean leaf and root tissue-specific promoters in Arabidopsis and soybean	8
Sequence modification on demand: search and replace tools for precise gene editing in plants	8
Lessons learned from the introduction of genetically engineered crops: relevance to gene drive deployment in Africa	7
Genetic quality: a complex issue for experimental study reproducibility	7
Overexpression of an aquaporin protein from Aspergillus glaucus confers salt tolerance in transgenic soybean	7
Peri-natal growth retardation rate and fat mass accumulation in mice lacking Dip2A is dependent on the dietary composition	6
Improving the politics of biotechnological innovations in food security and other sustainable development goals	6
Larval mosquito management and risk to aquatic ecosystems: A comparative approach including current tactics and gene-drive Anopheles techniques	6
Multilevel interactions between native and ectopic isoprenoid pathways affect global metabolism in rice	6
The human EF1a promoter does not provide expression of the transgene in mice	6
Production of gene-edited pigs harboring orthologous human mutations via double cutting by CRISPR/Cas9 with long single-stranded DNAs as homology-directed repair templates by zygote injection	6
Generation of C-to-G transversion in mouse embryos via CG editors	5
Esophageal striated muscle hypertrophy and muscle fiber type transformation in MSTN knockout pigs	5
Conversion of sheath blight susceptible indica and japonica rice cultivars into moderately resistant through expression of antifungal β-1,3-glucanase transgene from Trichoderma spp.	5
Genetically modified maize impacts in Honduras: production and social issues	5
Enhancing plant growth and biomass production by overexpression of GA20ox gene under control of a root preferential promoter	5
Elastin-like polypeptide and γ-zein fusions significantly increase recombinant protein accumulation in soybean seeds	5
Evaluation of potential impacts on biodiversity of the salt-tolerant transgenic Eucalyptus camaldulensis harboring an RNA chaperonic RNA-Binding-Protein gene derived from common ice plant	4
Effect of low VEGF on lung development and function	4
Timely gene detection assay and reliable screening of genetically engineered plants using an improved direct PCR-based technology	4
Bioengineering potato plants to produce benzylglucosinolate for improved broad-spectrum pest and disease resistance	4
Skeletal muscle phenotyping of Hippo gene-mutated mice reveals that Lats1 deletion increases the percentage of type I muscle fibers	4
Mini review: genome and transcriptome editing using CRISPR-cas systems for haematological malignancy gene therapy	4
History of safe exposure and bioinformatic assessment of phosphomannose-isomerase (PMI) for allergenic risk	4
Delayed body development with reduced triglycerides levels in leptin transgenic pigs	4
Ectopic expression of MYB repressor GmMYB3a improves drought tolerance and productivity of transgenic peanuts (Arachis hypogaea L.) under conditions of water deficit	4
Transient expression of an scFvG8 antibody in plants and characterization of its effects on the virulence factor pthA of Xanthomonas citri subsp. citri	4
An Agrobacterium strain auxotrophic for methionine is useful for switchgrass transformation	3
Points to consider in seeking biosafety approval for research, testing, and environmental release of experimental genetically modified biocontrol products during research and development	3
A DEAD box helicase Psp68 positively regulates salt stress responses in marker-free transgenic rice plants	3
Wheat α-gliadin and high-molecular-weight glutenin subunit accumulate in different storage compartments of transgenic soybean seed	3
Purslane (Portulaca oleracea L.) as a novel green-bioreactor for expression of human serum albumin (HSA) gene	3
MsSAMS, a cold stress-responsive gene, provides resistance to environmental stress in T2-generation transgenic plants	3

Enhanced resistance to soybean cyst nematode in transgenic soybean via host-induced silencing of vital Heterodera glycines genes	3
A comprehensive analysis of TDO2 expression in immune cells and characterization of immune cell phenotype in TDO2 knockout mice	3
Comparative evaluation of resistance to potato virus Y (PVY) in three different RNAi-based transgenic potato plants	3
Diversity of transgenes in sustainable management of insect pests	3
Lactoferrin and its role in biotechnological strategies for plant defense against pathogens	3
Development of a facile genetic transformation system for the Spanish elite rice paella genotype Bomba	3
Engineering a feedback inhibition-insensitive plant dihydrodipicolinate synthase to increase lysine content in Camelina sativa seeds	3
Generation and identification of endothelial-specific Hrh2 knockout mice	3
The potential oncogenic effect of tissue-specific expression of JC polyoma T antigen in digestive epithelial cells	3
Generation of a novel decay accelerating factor (DAF) knock-out rat model using clustered regularly-interspaced short palindromic repeats, (CRISPR)/associated protein 9 (Cas9), genome editing	3
Identification, purification, and pharmacological activity analysis of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAα1) expressed in transgenic rabbit mammary glands	3
Bioproduction of n-3 polyunsaturated fatty acids by nematode fatty acid desaturases and elongase in Drosophila melanogaster	3
Functional characterization of transcriptional activator gene SIARRI in tomato reveals its role in fruit growth and ripening	3
Methylation silencing and reactivation of exogenous genes in lentivirus-mediated transgenic mice	3
CRISPR/Cas9-mediated multiple guide RNA-targeted mutagenesis in the potato	3
Direct and pleiotropic effects of the Masou Salmon Delta-5 Desaturase transgene in F1 channel catfish (Ictalurus punctatus)	3
Establishment of Agrobacterium-mediated transformation system to Juglans sigillata Dode ‘Qianhe-7’	2
Data challenges for future plant gene editing: expert opinion	2
Novel Hina alleles created by genome editing increase grain hardness and reduce grain width in barley	2
Survivorship and food consumption of immatures and adults of Apis mellifera and Scaptotrigona bipunctata exposed to genetically modified eucalyptus pollen	2
Efficacy of drought-tolerant and insect-protected transgenic TELA® maize traits in Nigeria	2
GEnZ explorer: a tool for visualizing agroclimate to inform research and regulatory risk assessment	2
Mass spectrometric analysis of digesta does not improve the allergenicity assessment of GM crops	2
Expression of Cre recombinase in chondrocytes causes abnormal craniofacial and skeletal development	2
Overexpression of chrysanthemyl diphosphate synthase (CDS) gene in Tagetes erecta leads to the overproduction of pyrethrin	2
Efficiency comparison of B6(Cg)-Tyrc−2j /J and C57BL/6NTac embryos as hosts for the generation of knockout mice	2
Usefulness of current sgRNA design guidelines and in vitro cleavage assays for plant CRISPR/Cas genome editing: a case targeting the polyphenol oxidase gene family in eggplant (Solanum melongena L.)	2
Transgenic HPV11-E2 protein modulates URR activity in vivo	2
Kinetics of alpha-synuclein depletion in three brain regions following conditional pan-neuronal inactivation of the encoding gene (Snca) by tamoxifen-induced Cre-recombination in adult mice	2
Development of Agrobacterium-mediated in planta transformation protocol through coleoptile in rice	2
Degradation of transgenic Bacillus thuringiensis proteins in corn tissue in response to post-harvest management practices	2
Preface: Genome editing in plants	2
Myostatin deficiency decreases cardiac extracellular matrix in pigs	2
Efficient identification of genomic insertions and flanking regions through whole-genome sequencing in three transgenic soybean events	2
Biochemical and clinical studies of putative allergens to assess what distinguishes them from other non-allergenic proteins in the same family	2