OOIR: Observatory of International Research

Papers

(The TQCC of Statistical Methods in Medical Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Exact interval estimation for the linear combination of binomial proportions	264
Confidence estimation based on data from independent studies	164
Joint meta-analysis of two diagnostic tests accounting for within and between studies dependence	80
Investigations of sharp bounds for causal effects under selection bias	56
A new cure model accounting for longitudinal data and flexible patterns of hazard ratios over time	51
A Bayesian beta-binomial piecewise growth mixture model for longitudinal overdispersed binomial data	46
Covariate adjustment in Bayesian adaptive randomized controlled trials	46
Implementing response-adaptive designs when responses are missing: Impute or ignore?	45
Semiparametric copula method for semi-competing risks data subject to interval censoring and left truncation: Application to disability in elderly	41
Omnibus test for restricted mean survival time based on influence function	33
Interval estimation in three-class receiver operating characteristic analysis: A fairly general approach based on the empirical likelihood	29
Bayesian feature selection in joint models with application to a cardiovascular disease cohort study	27
Modeling and estimating a threshold effect: An application to improving cardiac surgery practices	27
A family of Bayesian prognostic and predictive covariate-adjusted response-adaptive randomization designs	22
New clinical trial design borrowing information across patient subgroups based on fusion-penalized regression models	20
Generalised pairwise comparisons for trend: An extension to the win ratio and win odds for dose-response and prognostic variable analysis with arbitrary statements of outcome preference	19
Correlational analyses of biomarkers that are harmonized through a bridging study due to measurement errors	18
Efficient design of partially nested randomized trials: A maximin approach	18
A capture-recapture modeling framework emphasizing expert opinion in disease surveillance	16
Accounting for informative observation process in transition models of binary longitudinal outcome: Application to medical record data	15
Analyzing heterogeneity in biomarker discriminative performance through partial time-dependent receiver operating characteristic curve modeling	15
A new information integration framework for complex models with applications to real-world data	14
Multiplicative versus additive modelling of causal effects using instrumental variables for survival outcomes – a comparison	14
On flexible inverse probability of treatment and intensity weighting: Informative censoring, variable selection, and weight trimming	14
Using shrinkage methods to estimate treatment effects in overlapping subgroups in randomized clinical trials with a time-to-event endpoint	14

Random survival forests with multivariate longitudinal endogenous covariates	14
Familywise error rate control for block response-adaptive randomization	13
Quantile inference for multivariate response regression in joint modeling of longitudinal and survival data	13
Simultaneous confidence intervals for an extended Koch-Röhmel design in three-arm non-inferiority trials	13
Generalized Bayesian kernel machine regression	13
Covariate selection for optimizing balance with an innovative adaptive randomization approach	12
Competing risks models with two time scales	12
A unified approach based on multidimensional scaling for calibration estimation in survey sampling with qualitative auxiliary information	12
Evaluating prognostic biomarkers for survival outcomes subject to informative censoring	12
An iterative matrix uncertainty selector for high-dimensional generalized linear models with measurement errors	11
Smoothing Lexis diagrams using kernel functions: A contemporary approach	11
Penalized variable selection in multi-parameter regression survival modeling	11
A simple and robust parametric shared frailty model for recurrent events with the competing risk of death: An application to the Carvedilol Prospective Randomized Cumulative Survival trial	11
Bayesian order constrained adaptive design for phase II clinical trials evaluating subgroup-specific treatment effect	10
Quantification of the influence of risk factors with application to cardiovascular diseases in subjects with type 1 diabetes	10
A Bayesian genomic selection approach incorporating prior feature ordering and population structures with application to coronary artery disease	10
Quantifying proportion of treatment effect by surrogate endpoint under heterogeneity	10
Empowering classification for multivariate functional data with simultaneous feature selection	10
Model-based adaptive randomization procedures for heteroscedasticity of treatment responses	9
Modified Brier score for evaluating prediction accuracy for binary outcomes	9
The effect of estimating prevalences on the population-wise error rate	9
Linearized maximum rank correlation estimation of doubly truncated data	9
Hazard-based distributional regression via ordinary differential equations	9
Adjusting for switches to multiple treatments: Should switches be handled separately or combined?	9
Change plane model averaging for subgroup identification	8
Testing for marginal covariate effect when the subgroup size induced by the covariate is informative	8
More efficient estimators of the area under the receiver operating characteristic curve in paired ranked set sampling	8
Addressing nonignorable missing data and heterogeneity in prognostic biomarker assessment	8
Adaptive sample size re-estimation designs for a two-stage randomized trial with binary outcome	8
A tight fit of the SIR dynamic epidemic model to daily cases of COVID-19 reported during the 2021–2022 Omicron surge in New York City: A novel approach	8
qTPI: A quasi-toxicity probability interval design for phase I trials with multiple-grade toxicities	8
Complete effect decomposition for an arbitrary number of multiple ordered mediators with time-varying confounders: A method for generalized causal multi-mediation analysis	8
Review of sample size determination methods for the intraclass correlation coefficient in the one-way analysis of variance model	8
A generalization of moderated statistics to data adaptive semiparametric estimation in high-dimensional biology	8
Improved survival analysis with shrinkage Kibria–Lukman estimators in the Cox model: Application to lung cancer data	8
Sample size calculation for multi-arm parallel design with restricted mean survival time	8
BOIN-ETC: A Bayesian optimal interval design considering efficacy and toxicity to identify the optimal dose combinations	7
A practical review of response-adaptive randomization: Under-explored challenges and potential directions	7
Statistical methods for clinical trials interrupted by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic: A review	7
An effective method for modeling highly correlated interaction models with applications in Alzheimer’s disease analysis	7
Regression analysis of multivariate recurrent event data allowing time-varying dependence with application to stroke registry data	7
Estimand-based inference in the presence of long-term survivors	7
Cause-specific hazard Cox models with partly interval censoring – Penalized likelihood estimation using Gaussian quadrature	7
Fixed and random effect selections in generalized linear mixed models	7
Combining multiple biomarkers linearly to minimize the Euclidean distance of the closest point on the receiver operating characteristic surface to the perfection corner in trichotomous settings	7
Discrimination performance in illness-death models with interval-censored disease data	7
Estimation and inference on the partial volume under the receiver operating characteristic surface	7
Test sensitivity in a prospective cancer screening program: A critique of a common proxy measure	7
Estimation in discrete time coarsened multivariate longitudinal models	7
Using short-term endpoints to improve interim decision making and trial duration in two-stage phase II trials with nested binary endpoints	6

Local linear approximation with Laplacian smoothing penalty and application in biology	6
Using circulating tumor DNA as a novel biomarker of efficacy for dose-finding designs in oncology	6
Handling missing data, skewness, and outliers in medical research: A robust factor analysis approach using the canonical fundamental skew-t distribution	6
Improved and computationally stable estimation of relative risk regression with one binary exposure	6
Using Bayesian evidence synthesis to quantify uncertainty in population trends in smoking behaviour	6
A Weibull mixture cure frailty model for high-dimensional covariates	6
Time-dependent receiver operating characteristic curve estimator for correlated right-censored time-to-event data	6
Generalized fiducial inference for the restricted mean survival time	6
A new framework for semi-Markovian parametric multi-state models with interval censoring	6
A Bayesian latent class approach to causal inference with longitudinal data	6
Interval estimation for the Youden index of a continuous diagnostic test with verification biased data	6
Multiple imputation approaches for epoch-level accelerometer data in trials	6
Editorial	6
A generalized epidemiological model with dynamic and asymptomatic population	6
Bivariate copula regression models for semi-competing risks	5
The “Why” behind including “Y” in your imputation model	5
Group sequential analysis of marked point processes: Plasma donation trials	5
Joint estimation of multiple graphical models for an fMRI study of brain connectivity networks	5
A hybrid prior Bayesian method for combining domestic real-world data and overseas data in global drug development	5
Sample sizes required to estimate the protective efficacy of a vaccine when there is an unequal allocation of individuals across the vaccine and placebo groups	5
Group lasso priors for Bayesian accelerated failure time models with left-truncated and interval-censored data	5
Heterogeneous treatment effect estimation for observational data using model-based forests	5
Additive hazards model with time-varying coefficients and imaging predictors	5
Distribution-free control charts for mixed-type data based on rank of interpoint distances	5
An overview of optimal designs under a given budget in cluster randomized trials with a binary outcome	5
LASSO-type instrumental variable selection methods with an application to Mendelian randomization	5
Comparison of statistical methods for the analysis of patient-reported outcomes in randomised controlled trials: A simulation study	5
Adaptive enrichment trial designs using joint modelling of longitudinal and time-to-event data	5
Semiparametric generalized estimating equations for repeated measurements in cross-over designs	5
Bayesian analysis of joint quantile regression for multi-response longitudinal data with application to primary biliary cirrhosis sequential cohort study	5
Use of clinical tolerance limits for assessing agreement	5
Data-driven clustering of infectious disease incidence into age groups	5
Covariate hypothesis tests for the cure rate in mixture cure models based on martingale difference correlation	5
Confidence intervals and point estimates for treatment effects in adaptive enrichment designs	5
Penalized estimation of general frailty Poisson models for recurrent count events	5
Augmented two-stage estimation for treatment switching in oncology trials: Leveraging external data for improved precision	5
Health utility adjusted survival: A composite endpoint for clinical trial designs	5
Factorial survival analysis for treatment effects under dependent censoring	4
Joint model with latent disease age: Overcoming the need for reference time	4
A Bayesian transformation model for informative partly interval-censored data with covariates subject to measurement error	4
Biomarker-driven optimal designs for patient enrollment restriction	4
Using inverse probability of censoring weighting to estimate hypothetical estimands in clinical trials: Should we implement stabilisation, and if so how?	4
Restricted mean survival time in cluster randomized trials with a small number of clusters: Improving variance estimation of the intervention effect from the pseudo-values regression	4
Sample size determination for adaptive crossover trial in detecting gene-drug interactions	4
Efficient algorithms for survival data with multiple outcomes using the frailty model	4
Comparisons of various estimates of the I2 statistic for quantifying between-study heterogeneity in meta-analysis	4
Quantile outcome adaptive lasso: Covariate selection for inverse probability weighting estimator of quantile treatment effects	4
Divided-and-combined omnibus test for genetic association analysis with high-dimensional data	4
Causal rule ensemble method for estimating heterogeneous treatment effect with consideration of prognostic effects	4
Strategies to boost statistical efficiency in randomized oncology trials with primary time-to-event endpoints	4
Graphical methods to illustrate the nature of the relation between a continuous variable and the outcome when using restricted cubic splines with a Cox proportional hazards model	4
Measuring the individualization potential of treatment individualization rules: Application to rules built with a new parametric interaction model for parallel-group clinical trials	4
Bivariate joint models for survival and change of cognitive function	4
Methods for comparative effectiveness based on time to confirmed disability progression with irregular observations in multiple sclerosis	4
Regularization approaches in clinical biostatistics: A review of methods and their applications	4
Vaccine efficacy estimands and power considerations	4
Covariate-adjusted inference for doubly adaptive biased coin design	4
Average treatment effect on the treated, under lack of positivity	4
Estimating dynamic treatment regimes for ordinal outcomes with household interference: Application in household smoking cessation	4
Quantifying the effects of air pollution on respiratory ill health treated in primary care when the locations of the populations at risk are partially unknown	4
Simulating time-to-event data subject to competing risks and clustering: A review and synthesis	4
Diagnostic accuracy analysis for multiple raters using probit hierarchical model for ordinal ratings	4
Extended excess hazard models for spatially dependent survival data	4