OOIR: Observatory of International Research

Papers

(The TQCC of Statistical Methods in Medical Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Simulation models for aggregated data meta-analysis: Evaluation of pooling effect sizes and publication biases	91
Adaptive enrichment trial designs using joint modelling of longitudinal and time-to-event data	62
A latent class linear mixed model for monotonic continuous processes measured with error	55
Joint regression analysis of clustered current status data with latent variables	50
Variance estimation for the average treatment effects on the treated and on the controls	44
Bayesian multiple Gaussian graphical models for multilevel variables from unknown classes	32
The “Why” behind including “Y” in your imputation model	29
A generalized epidemiological model with dynamic and asymptomatic population	25
Estimating target population treatment effects in meta-analysis with individual participant-level data	25
Simulation extrapolation method for measurement error: A review	24
Estimating drug concentration–response relationships by applying causal inference methods for continuous point exposures and time-to-event outcomes	22
Bayesian analysis of joint quantile regression for multi-response longitudinal data with application to primary biliary cirrhosis sequential cohort study	22
A Bayesian beta-binomial piecewise growth mixture model for longitudinal overdispersed binomial data	19
A matching-based machine learning approach to estimating optimal dynamic treatment regimes with time-to-event outcomes	18
A unified approach to power and sample size determination for log-rank tests under proportional and nonproportional hazards	17
Optimal study designs for cluster randomised trials: An overview of methods and results	17
ROSIE: RObust Sparse ensemble for outlIEr detection and gene selection in cancer omics data	17
Interval estimation in three-class receiver operating characteristic analysis: A fairly general approach based on the empirical likelihood	17
Multivariate generalized linear mixed models for continuous bounded outcomes: Analyzing the body fat percentage data	17
Frequentist rules for regulatory approval of subgroups in phase III trials: A fresh look at an old problem	17
Regression analysis of a future state entry time distribution conditional on a past state occupation in a progressive multistate model	16
Semiparametric copula method for semi-competing risks data subject to interval censoring and left truncation: Application to disability in elderly	16
The staircase cluster randomised trial design: A pragmatic alternative to the stepped wedge	15
Sample sizes required to estimate the protective efficacy of a vaccine when there is an unequal allocation of individuals across the vaccine and placebo groups	15
Leveraging historical data to optimize the number of covariates and their explained variance in the analysis of randomized clinical trials.	15

Approximate Bayesian computation design for phase I clinical trials	14
Analysis of hospital readmissions with competing risks	14
Accounting for regression to the mean under the bivariate t-distribution	13
Use of clinical tolerance limits for assessing agreement	13
Logistic regression with correlated measurement error and misclassification in covariates	12
Simultaneous inference procedures for the comparison of multiple characteristics of two survival functions	12
Goodness-of-fit tests for modified Poisson regression possibly producing fitted values exceeding one in binary outcome analysis	12
Reference ranges: Why tolerance intervals should not be used. Comment on Liu, Bretz and Cortina-Borja, Reference range: Which statistical intervals to use? SMMR, 2021,Vol. 30(2) 523–534	11
Standardization of continuous and categorical covariates in sparse penalized regressions	11
Time-varying coefficient additive hazards model with latent variables	11
A novel rare variants association test for binary traits in family-based designs via copulas	11
A comparison of two frameworks for multi-state modelling, applied to outcomes after hospital admissions with COVID-19	11
Impact of unequal censoring and insufficient follow-up on comparing survival outcomes: Applications to clinical studies	11
Bayesian blockwise inference for joint models of longitudinal and multistate data with application to longitudinal multimorbidity analysis	10
Estimating latent, dynamic processes of breast cancer tumour growth and distant metastatic spread from mammography screening data	10
Covariate adjustment in Bayesian adaptive randomized controlled trials	10
Comparison between inverse-probability weighting and multiple imputation in Cox model with missing failure subtype	9
Joint meta-analysis of two diagnostic tests accounting for within and between studies dependence	8
Matching ratio and sample size for optimal sequential testing with binomial data	8
Equivalence tests for ratio of means in bioequivalence studies under crossover design	8
Model-based optimal randomization procedure for treatment–covariate interaction tests	8
Using dichotomized survival data to construct a prior distribution for a Bayesian seamless Phase II/III clinical trial	8
A review of multistate modelling approaches in monitoring disease progression: Bayesian estimation using the Kolmogorov-Chapman forward equations	8
Optimal sampling allocation for outcome-dependent designs in cluster-correlated data settings	8
Comparison of statistical methods for the analysis of patient-reported outcomes in randomised controlled trials: A simulation study	8
Copula modeling for the estimation of measures of marker classification and predictiveness performance with survival outcomes	8
Unbiased and robust analysis of co-localization in super-resolution images	8
Improved semi-parametric inference for a mixture model of responses from a control versus treatment group trial	8
Mediation effects that emulate a target randomised trial: Simulation-based evaluation of ill-defined interventions on multiple mediators	8
Exact interval estimation for the linear combination of binomial proportions	7
Sample size determination for stepped wedge cluster randomized trials in pragmatic settings	7
Robust integration of secondary outcomes information into primary outcome analysis in the presence of missing data	7
Evaluating Bayesian adaptive randomization procedures with adaptive clip methods for multi-arm trials	7
Instrumental variable analysis with categorical treatment	7
Refined moderation analysis with binary outcomes in precision medicine research	7
Design and analysis of factorial clinical trials: The impact of one treatment's effectiveness on the statistical power and required sample size of the other	7
Non-parametric treatment time-lag effect estimation	7
Weighted reverse counting process (WRCP): A novel approach to quantify the overall treatment effect with multiple time-to-event outcomes by adaptive weighting	7
Partly linear single-index cure models with a nonparametric incidence link function	7
Clustering minimal inhibitory concentration data through Bayesian mixture models: An application to detect Mycobacterium tuberculosis resistance mutations	7
Sensitivity analysis for unmeasured confounding in estimating the difference in restricted mean survival time	7
A general consonance principle for closure tests based on p-values	6
Nonparametric Bayesian Q-learning for optimization of dynamic treatment regimes in the presence of partial compliance	6
Combining cox regressions across a heterogeneous distributed research network facing small and zero counts	6
A model-based approach for historical borrowing, with an application to neovascular age-related macular degeneration	6
Dynamic survival analysis: Modelling the hazard function via ordinary differential equations	6
Estimating the sample mean and standard deviation from order statistics and sample size in meta-analysis	6
Semiparametric generalized estimating equations for repeated measurements in cross-over designs	6
Statistical methods for analysis of combined biomarker data from multiple nested case–control studies	6
Variance partitioning in spatio-temporal disease mapping models	6

Regression analysis of longitudinal data with random change point	6
Demystifying estimands in cluster-randomised trials	6
Point estimation following a two-stage group sequential trial	6
Solutions to problems of nonexistence of parameter estimates and sparse data bias in Poisson regression	6
A novel model-checking approach for dose-response relationships	6
Bivariate copula regression models for semi-competing risks	6
Omnibus test for restricted mean survival time based on influence function	6
Calibrating validation samples when accounting for measurement error in intervention studies	6
Testing for treatment effect in covariate-adaptive randomized trials with generalized linear models and omitted covariates	5
Detecting the skewness of data from the five-number summary and its application in meta-analysis	5
Weighted functional linear Cox regression model	5
Variable selection for a mark-specific additive hazards model using the adaptive LASSO	5
A Bayesian quasi-likelihood design for identifying the minimum effective dose and maximum utility dose in dose-ranging studies	5
LASSO-type instrumental variable selection methods with an application to Mendelian randomization	5
Generalized fiducial inference for the restricted mean survival time	5
Unified approach to optimal estimation of mean and standard deviation from sample summaries	5
Heterogeneous treatment effect estimation for observational data using model-based forests	5
Multivariate control charts for monitoring a bivariate correlated count process with application to meningococcal disease	5
The change in estimate method for selecting confounders: A simulation study	5
Estimating transformations for evaluating diagnostic tests with covariate adjustment	5
Random survival forests with multivariate longitudinal endogenous covariates	5
Flexible semiparametric mode regression for time-to-event data	5
Model-free screening for variables with treatment interaction	5
Regularization approaches in clinical biostatistics: A review of methods and their applications	5
A functional proportional hazard cure rate model for interval-censored data	5
Evaluations of the sum-score-based and item response theory-based tests of group mean differences under various simulation conditions	5
Group lasso priors for Bayesian accelerated failure time models with left-truncated and interval-censored data	5
Confidence estimation based on data from independent studies	5
Logistic regression vs. predictive mean matching for imputing binary covariates	5
An objective Bayesian approach to estimation in multistage experiments	5
Goodness-of-fit tests for a logistic regression model with missing covariates	5
Estimation of the proportion of true null hypotheses under sparse dependence: Adaptive FDR controlling in microarray data	5
Methods for non-proportional hazards in clinical trials: A systematic review	5
Glucodensities: A new representation of glucose profiles using distributional data analysis	5
A sequential test to compare the real-time fatality rates of a disease among multiple groups with an application to COVID-19 data	5
Divided-and-combined omnibus test for genetic association analysis with high-dimensional data	5
Design and analysis of partially randomized preference trials with propensity score stratification	5
Editorial	5
Commentary on the use of the reproduction number R during the COVID-19 pandemic	5
Comparison of parametric and semi-parametric models with randomly right-censored data by weighted estimators: Two applications in colon cancer and hepatocellular carcinoma datasets	5
l₂-Penalized temporal logit-mixed models for the estimation of regional obesity prevalence over time	5
Imputation and missing indicators for handling missing data in the development and deployment of clinical prediction models: A simulation study	5
Repeated measures discriminant analysis using multivariate generalized estimation equations	4
An additive-multiplicative model for longitudinal data with informative observation times	4
A multi-state Markov model using notification data to estimate HIV incidence, number of undiagnosed individuals living with HIV, and delay between infection and diagnosis: Illustration in France, 2008	4
Using a centered general linear model for detection of interactions among biomarkers	4
Weighted mean difference statistics for paired data in the presence of missing values	4
Challenges of modelling approaches for network meta-analysis of time-to-event outcomes in the presence of non-proportional hazards to aid decision making: Application to a melanoma network	4
Mediational g-formula for time-varying treatment and repeated-measured multiple mediators: Application to atorvastatin’s effect on cardiovascular disease via cholesterol lowering and anti-inflammatory	4
Conversion of non-inferiority margin from hazard ratio to restricted mean survival time difference using data from multiple historical trials	4
Developing clinical prediction models when adhering to minimum sample size recommendations: The importance of quantifying bootstrap variability in tuning parameters and predictive performance	4
Determination of correlations in multivariate count data with informative observation times	4
The benefits of covariate adjustment for adaptive multi-arm designs	4
Using joint models for longitudinal and time-to-event data to investigate the causal effect of salvage therapy after prostatectomy	4
Data-driven clustering of infectious disease incidence into age groups	4
Response-adaptive treatment randomization for multiple comparisons of treatments with recurrent event responses	4
MEGH: A parametric class of general hazard models for clustered survival data	4
Fallopian tube anatomy predicts pregnancy and pregnancy outcomes after tubal reversal surgery	4
Concordance correlation coefficients estimated by modified variance components and generalized estimating equations for longitudinal overdispersed Poisson data	4
Analyzing heterogeneity in biomarker discriminative performance through partial time-dependent receiver operating characteristic curve modeling	4
Between-group comparison of area under the curve in clinical trials with censored follow-up: Application to HIV therapeutic vaccines	4
A unified approach to variable selection for Cox’s proportional hazards model with interval-censored failure time data	4
Adaptive group sequential survival comparisons based on log-rank and pointwise test statistics	4
Nonparametric analysis of doubly truncated and interval-censored data	4
Promising zone two-stage design for a single-arm study with binary outcome	4
Bayesian analysis of longitudinal binary responses based on the multivariate probit model: A comparison of five methods	4
Modeling and estimating a threshold effect: An application to improving cardiac surgery practices	4
A bivariate zero-inflated negative binomial model and its applications to biomedical settings	4
Improving transportability of randomized controlled trial inference using robust prediction methods	4