Statistical Methods in Medical Research

Papers
(The TQCC of Statistical Methods in Medical Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Detecting the skewness of data from the five-number summary and its application in meta-analysis61
Estimating the sample mean and standard deviation from order statistics and sample size in meta-analysis47
Minimum sample size for developing a multivariable prediction model using multinomial logistic regression45
Multiple imputation with missing data indicators45
Predictive performance of machine and statistical learning methods: Impact of data-generating processes on external validity in the “large N, small p” setting37
Small sample sizes: A big data problem in high-dimensional data analysis36
Estimation of required sample size for external validation of risk models for binary outcomes31
Conditional copula models for correlated survival endpoints: Individual patient data meta-analysis of randomized controlled trials29
Spatial scan statistics can be dangerous25
Commentary on the use of the reproduction number R during the COVID-19 pandemic23
Adjusting for selection bias due to missing data in electronic health records-based research23
Fitting to the UK COVID-19 outbreak, short-term forecasts and estimating the reproductive number20
Mediation effects that emulate a target randomised trial: Simulation-based evaluation of ill-defined interventions on multiple mediators18
Glucodensities: A new representation of glucose profiles using distributional data analysis18
A Bayesian dose–response meta-analysis model: A simulations study and application17
The change in estimate method for selecting confounders: A simulation study16
Statistical methods used to combine the effective reproduction number, R(t), and other related measures of COVID-19 in the UK16
Revisiting performance metrics for prediction with rare outcomes16
Developing clinical prediction models when adhering to minimum sample size recommendations: The importance of quantifying bootstrap variability in tuning parameters and predictive performance16
Propensity score analysis methods with balancing constraints: A Monte Carlo study16
On recurrent-event win ratio15
Inferring risks of coronavirus transmission from community household data14
Sample size estimation for modified Poisson analysis of cluster randomized trials with a binary outcome14
Unbiasedness and efficiency of non-parametric and UMVUE estimators of the probabilistic index and related statistics14
Meta-analysis of the severe acute respiratory syndrome coronavirus 2 serial intervals and the impact of parameter uncertainty on the coronavirus disease 2019 reproduction number13
Methods for modelling excess mortality across England during the COVID-19 pandemic13
Standard error estimation in meta-analysis of studies reporting medians13
Imputation and missing indicators for handling missing data in the development and deployment of clinical prediction models: A simulation study13
An overview of propensity score matching methods for clustered data12
On estimating the area under the ROC curve in ranked set sampling12
General regression methods for respondent-driven sampling data12
G-computation and doubly robust standardisation for continuous-time data: A comparison with inverse probability weighting12
A unified approach to variable selection for Cox’s proportional hazards model with interval-censored failure time data11
Modified Brier score for evaluating prediction accuracy for binary outcomes11
Statistical design considerations for trials that study multiple indications10
Deselection of base-learners for statistical boosting—with an application to distributional regression10
Mediation analysis for mixture Cox proportional hazards cure models10
Class imbalance in gradient boosting classification algorithms: Application to experimental stroke data10
Online control of the familywise error rate10
Applications of simple and accessible methods for meta-analysis involving rare events: A simulation study10
Variable selection with missing data in both covariates and outcomes: Imputation and machine learning10
Regularization approaches in clinical biostatistics: A review of methods and their applications10
Flexible extension of the accelerated failure time model to account for nonlinear and time-dependent effects of covariates on the hazard10
Variable selection for causal mediation analysis using LASSO-based methods10
Dealing with risk discontinuities to estimate cancer mortality risks when the number of small areas is large10
Online control of the False Discovery Rate in group-sequential platform trials9
Efficient and flexible simulation-based sample size determination for clinical trials with multiple design parameters9
Inferring median survival differences in general factorial designs via permutation tests9
A comparison of two frameworks for multi-state modelling, applied to outcomes after hospital admissions with COVID-199
A family of Gamma-generated distributions: Statistical properties and applications9
Estimating a time-to-event distribution from right-truncated data in an epidemic: A review of methods9
An adaptive seamless Phase 2-3 design with multiple endpoints8
Inference on the overlap coefficient: The binormal approach and alternatives8
Challenges of modelling approaches for network meta-analysis of time-to-event outcomes in the presence of non-proportional hazards to aid decision making: Application to a melanoma network8
Sample sizes for cluster-randomised trials with continuous outcomes: Accounting for uncertainty in a single intra-cluster correlation estimate8
Efficiency of a randomized confirmatory basket trial design constrained to control the family wise error rate by indication8
Correlation-based joint feature screening for semi-competing risks outcomes with application to breast cancer data8
Two-phase analysis and study design for survival models with error-prone exposures8
A general method for calculating power for GEE analysis of complete and incomplete stepped wedge cluster randomized trials8
Improving convergence in growth mixture models without covariance structure constraints8
Improving the estimation of the COVID-19 effective reproduction number using nowcasting8
Exploring consequences of simulation design for apparent performance of methods of meta-analysis7
A distribution-free control charting technique based on change-point analysis for detection of epidemics7
Ensemble methods for survival function estimation with time-varying covariates7
Combining cox regressions across a heterogeneous distributed research network facing small and zero counts7
Spatiotemporal distributed lag modelling of multiple Plasmodium species in a malaria elimination setting7
Distance-based Classification and Regression Trees for the analysis of complex predictors in health and medical research7
Nonparametric kernel estimation of the probability of cure in a mixture cure model when the cure status is partially observed7
CWL: A conditional weighted likelihood method to account for the delayed joint toxicity–efficacy outcomes for phase I/II clinical trials7
A permutation test for assessing the presence of individual differences in treatment effects7
Testing for treatment effect in covariate-adaptive randomized trials with generalized linear models and omitted covariates7
A method for systematically ranking therapeutic drug candidates using multiple uncertain screening criteria6
MEGH: A parametric class of general hazard models for clustered survival data6
Statistical reproducibility for pairwise t-tests in pharmaceutical research6
A comparison of analytical strategies for cluster randomized trials with survival outcomes in the presence of competing risks6
A dose–effect network meta-analysis model with application in antidepressants using restricted cubic splines6
Intervention treatment distributions that depend on the observed treatment process and model double robustness in causal survival analysis6
Continuous(ly) missing outcome data in network meta-analysis: A one-stage pattern-mixture model approach6
Bayesian variable selection in logistic regression with application to whole-brain functional connectivity analysis for Parkinson’s disease6
Risk difference tests for stratified binary data under Dallal’s model6
Adjusting for time of infection or positive test when estimating the risk of a post-infection outcome in an epidemic6
Mid-quantile regression for discrete responses6
Selecting the number of categories of the lymph node ratio in cancer research: A bootstrap-based hypothesis test6
CFO: Calibration-free odds design for phase I/II clinical trials6
An effective technique for diabetic retinopathy using hybrid machine learning technique6
Multiple imputation for cause-specific Cox models: Assessing methods for estimation and prediction6
Probability intervals of toxicity and efficacy design for dose-finding clinical trials in oncology6
A robust variable screening procedure for ultra-high dimensional data6
Uncertainty quantification for epidemiological forecasts of COVID-19 through combinations of model predictions6
Employing a latent variable framework to improve efficiency in composite endpoint analysis6
Re-randomisation trials in multi-episode settings: Estimands and independence estimators6
Revisiting Gaussian Markov random fields and Bayesian disease mapping5
Quantile regression models for survival data with missing censoring indicators5
Generalized quasi-linear mixed-effects model5
Bayesian adaptive decision-theoretic designs for multi-arm multi-stage clinical trials5
Association of intracluster correlation measures with outcome prevalence for binary outcomes in cluster randomised trials5
Benchmarking survival outcomes: A funnel plot for survival data5
The analysis of COVID-19 in-hospital mortality: A competing risk approach or a cure model?5
A Bayesian phase I/II biomarker-based design for identifying subgroup-specific optimal dose for immunotherapy5
A survival mediation model with Bayesian model averaging5
A support vector machine-based cure rate model for interval censored data5
Causal mediation analysis with multiple causally non-ordered and ordered mediators based on summarized genetic data5
Unified approach to optimal estimation of mean and standard deviation from sample summaries5
Estimation of the proportion of true null hypotheses under sparse dependence: Adaptive FDR controlling in microarray data5
Leveraging historical data to optimize the number of covariates and their explained variance in the analysis of randomized clinical trials.5
Net benefit separation and the determination curve: A probabilistic framework for cost-effectiveness estimation5
Robust statistical inference for matched win statistics5
Modeling treatment effect modification in multidrug-resistant tuberculosis in an individual patientdata meta-analysis5
Integrating relative survival in multi-state models—a non-parametric approach5
Review of sample size determination methods for the intraclass correlation coefficient in the one-way analysis of variance model5
Robust regression with asymmetric loss functions5
Regression analysis of multivariate interval-censored failure time data with informative censoring5
Logistic regression vs. predictive mean matching for imputing binary covariates5
A group sequential design and sample size estimation for an immunotherapy trial with a delayed treatment effect5
A review of multistate modelling approaches in monitoring disease progression: Bayesian estimation using the Kolmogorov-Chapman forward equations5
Methods of analysis for survival outcomes with time-updated mediators, with application to longitudinal disease registry data5
On estimating a constrained bivariate random effects model for meta-analysis of test accuracy studies5
MISL: Multiple imputation by super learning5
The asymptotic distribution of the Net Benefit estimator in presence of right-censoring5
Inference under covariate-adaptive randomization: A simulation study5
A semiparametric mixed-effects model for censored longitudinal data5
Negative controls: Concepts and caveats4
Promising zone two-stage design for a single-arm study with binary outcome4
Weighted functional linear Cox regression model4
Ranking procedures for repeated measures designs with missing data: Estimation, testing and asymptotic theory4
Sample size determination for stepped wedge cluster randomized trials in pragmatic settings4
Modeling the probability of occurrence of events4
Flexible modeling of multiple nonlinear longitudinal trajectories with censored and non-ignorable missing outcomes4
Combining multiple biomarkers to linearly maximize the diagnostic accuracy under ordered multi-class setting4
Clustering functional data using forward search based on functional spatial ranks with medical applications4
Quantile regression on inactivity time4
A state-space approach for longitudinal outcomes: An application to neuropsychological outcomes4
Joint space–time Bayesian disease mapping via quantification of disease risk association4
Multivariate generalized linear mixed models for continuous bounded outcomes: Analyzing the body fat percentage data4
A unified approach to power and sample size determination for log-rank tests under proportional and nonproportional hazards4
Clustered longitudinal data subject to irregular observation4
Sensitivity analyses in longitudinal clinical trials via distributional imputation4
A Poisson-multinomial spatial model for simultaneous outbreaks with application to arboviral diseases4
Inference for the treatment effect in longitudinal cluster randomized trials when treatment effect heterogeneity is ignored4
Evaluations of the sum-score-based and item response theory-based tests of group mean differences under various simulation conditions4
Goodness-of-fit tests for a logistic regression model with missing covariates4
Impact of minimal sufficient balance, minimization, and stratified permuted blocks on bias and power in the estimation of treatment effect in sequential clinical trials with a binary endpoint4
Unbiased and robust analysis of co-localization in super-resolution images4
Marginal structural models with latent class growth analysis of treatment trajectories: Statins for primary prevention among older adults4
Using information criteria to select smoothing parameters when analyzing survival data with time-varying coefficient hazard models4
A comparison of various aggregation functions in multi-criteria decision analysis for drug benefit–risk assessment4
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