Statistical Methods in Medical Research

Article	Citations
Covariate adjustment in Bayesian adaptive randomized controlled trials	203
Time-varying coefficient additive hazards model with latent variables	120
Interval estimation in three-class receiver operating characteristic analysis: A fairly general approach based on the empirical likelihood	46
Exact interval estimation for the linear combination of binomial proportions	38
Confidence estimation based on data from independent studies	35
Equivalence tests for ratio of means in bioequivalence studies under crossover design	34
Implementing response-adaptive designs when responses are missing: Impute or ignore?	31
A Bayesian beta-binomial piecewise growth mixture model for longitudinal overdispersed binomial data	27
A new cure model accounting for longitudinal data and flexible patterns of hazard ratios over time	27
Investigations of sharp bounds for causal effects under selection bias	26
Analysis of hospital readmissions with competing risks	21
Semiparametric copula method for semi-competing risks data subject to interval censoring and left truncation: Application to disability in elderly	21
Omnibus test for restricted mean survival time based on influence function	20
Joint meta-analysis of two diagnostic tests accounting for within and between studies dependence	20
Accounting for informative observation process in transition models of binary longitudinal outcome: Application to medical record data	19
Modeling and estimating a threshold effect: An application to improving cardiac surgery practices	19
A capture-recapture modeling framework emphasizing expert opinion in disease surveillance	17
Using shrinkage methods to estimate treatment effects in overlapping subgroups in randomized clinical trials with a time-to-event endpoint	17
On flexible inverse probability of treatment and intensity weighting: Informative censoring, variable selection, and weight trimming	16
Random survival forests with multivariate longitudinal endogenous covariates	15
Analyzing heterogeneity in biomarker discriminative performance through partial time-dependent receiver operating characteristic curve modeling	14
Response-adaptive treatment randomization for multiple comparisons of treatments with recurrent event responses	14
Multiplicative versus additive modelling of causal effects using instrumental variables for survival outcomes – a comparison	14
A family of Bayesian prognostic and predictive covariate-adjusted response-adaptive randomization designs	14
Nonparametric analysis of doubly truncated and interval-censored data	13

New clinical trial design borrowing information across patient subgroups based on fusion-penalized regression models	13
Challenges of modelling approaches for network meta-analysis of time-to-event outcomes in the presence of non-proportional hazards to aid decision making: Application to a melanoma network	13
Generalised pairwise comparisons for trend: An extension to the win ratio and win odds for dose-response and prognostic variable analysis with arbitrary statements of outcome preference	12
Correlational analyses of biomarkers that are harmonized through a bridging study due to measurement errors	12
A unified approach based on multidimensional scaling for calibration estimation in survey sampling with qualitative auxiliary information	11
Generalized Bayesian kernel machine regression	11
Simultaneous confidence intervals for an extended Koch-Röhmel design in three-arm non-inferiority trials	11
Bayesian order constrained adaptive design for phase II clinical trials evaluating subgroup-specific treatment effect	11
Quantification of the influence of risk factors with application to cardiovascular diseases in subjects with type 1 diabetes	10
Fitting joint models of longitudinal observations and time to event by sequential Bayesian updating	10
Covariate selection for optimizing balance with an innovative adaptive randomization approach	10
Quantifying proportion of treatment effect by surrogate endpoint under heterogeneity	10
Evaluating prognostic biomarkers for survival outcomes subject to informative censoring	10
Smoothing Lexis diagrams using kernel functions: A contemporary approach	10
Familywise error rate control for block response-adaptive randomization	10
Modeling the patient mix for risk-adjusted CUSUM charts	9
Penalized variable selection in multi-parameter regression survival modeling	9
Competing risks models with two time scales	9
A Bayesian genomic selection approach incorporating prior feature ordering and population structures with application to coronary artery disease	9
An iterative matrix uncertainty selector for high-dimensional generalized linear models with measurement errors	9
A simple and robust parametric shared frailty model for recurrent events with the competing risk of death: An application to the Carvedilol Prospective Randomized Cumulative Survival trial	9
Modified Brier score for evaluating prediction accuracy for binary outcomes	8
The effect of estimating prevalences on the population-wise error rate	8
Complete effect decomposition for an arbitrary number of multiple ordered mediators with time-varying confounders: A method for generalized causal multi-mediation analysis	8
Review of sample size determination methods for the intraclass correlation coefficient in the one-way analysis of variance model	8
Hunting for protective drugs at the break of a pandemic: Causal inference from hospital data	8
A generalization of moderated statistics to data adaptive semiparametric estimation in high-dimensional biology	8
Sample size calculation for multi-arm parallel design with restricted mean survival time	8
Adaptive sample size re-estimation designs for a two-stage randomized trial with binary outcome	8
A competing risks regression model for the association between time-varying opioid exposure and risk of overdose	8
Testing for marginal covariate effect when the subgroup size induced by the covariate is informative	8
Adjusting for switches to multiple treatments: Should switches be handled separately or combined?	8
Model-based adaptive randomization procedures for heteroscedasticity of treatment responses	8
More efficient estimators of the area under the receiver operating characteristic curve in paired ranked set sampling	8
The analysis of COVID-19 in-hospital mortality: A competing risk approach or a cure model?	8
Change plane model averaging for subgroup identification	8
BOIN-ETC: A Bayesian optimal interval design considering efficacy and toxicity to identify the optimal dose combinations	7
Space-time interactions in Bayesian disease mapping with recent tools: Making things easier for practitioners	7
A tight fit of the SIR dynamic epidemic model to daily cases of COVID-19 reported during the 2021–2022 Omicron surge in New York City: A novel approach	7
Cause-specific hazard Cox models with partly interval censoring – Penalized likelihood estimation using Gaussian quadrature	7
On recurrent-event win ratio	7
Regression analysis of multivariate recurrent event data allowing time-varying dependence with application to stroke registry data	7
CFO: Calibration-free odds design for phase I/II clinical trials	7
MISL: Multiple imputation by super learning	7
Fixed and random effect selections in generalized linear mixed models	7
Statistical methods for clinical trials interrupted by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic: A review	7
Using horseshoe prior for incorporating multiple historical control data in randomized controlled trials	7
qTPI: A quasi-toxicity probability interval design for phase I trials with multiple-grade toxicities	7
Estimation and inference on the partial volume under the receiver operating characteristic surface	7
Test sensitivity in a prospective cancer screening program: A critique of a common proxy measure	7

Using Bayesian evidence synthesis to quantify uncertainty in population trends in smoking behaviour	6
Interval estimation for the Youden index of a continuous diagnostic test with verification biased data	6
Multiple imputation approaches for epoch-level accelerometer data in trials	6
Comparison of statistical methods for the analysis of patient-reported outcomes in randomised controlled trials: A simulation study	6
Estimand-based inference in the presence of long-term survivors	6
Use of clinical tolerance limits for assessing agreement	6
Combining multiple biomarkers linearly to minimize the Euclidean distance of the closest point on the receiver operating characteristic surface to the perfection corner in trichotomous settings	6
Time-dependent receiver operating characteristic curve estimator for correlated right-censored time-to-event data	6
Generalized fiducial inference for the restricted mean survival time	6
A new framework for semi-Markovian parametric multi-state models with interval censoring	6
Sample sizes required to estimate the protective efficacy of a vaccine when there is an unequal allocation of individuals across the vaccine and placebo groups	6
A Weibull mixture cure frailty model for high-dimensional covariates	6
Mid-quantile regression for discrete responses	6
Improved and computationally stable estimation of relative risk regression with one binary exposure	6
A Bayesian latent class approach to causal inference with longitudinal data	6
Local linear approximation with Laplacian smoothing penalty and application in biology	6
Editorial	6
Using short-term endpoints to improve interim decision making and trial duration in two-stage phase II trials with nested binary endpoints	6
A generalized epidemiological model with dynamic and asymptomatic population	6
Estimation in discrete time coarsened multivariate longitudinal models	6
Using circulating tumor DNA as a novel biomarker of efficacy for dose-finding designs in oncology	6
MEGH: A parametric class of general hazard models for clustered survival data	5
Group sequential analysis of marked point processes: Plasma donation trials	5
Unified approach to optimal estimation of mean and standard deviation from sample summaries	5
Adaptive enrichment trial designs using joint modelling of longitudinal and time-to-event data	5
Penalized estimation of general frailty Poisson models for recurrent count events	5
Heterogeneous treatment effect estimation for observational data using model-based forests	5
Variance partitioning in spatio-temporal disease mapping models	5
Additive hazards model with time-varying coefficients and imaging predictors	5
Quantile outcome adaptive lasso: Covariate selection for inverse probability weighting estimator of quantile treatment effects	5
Factorial survival analysis for treatment effects under dependent censoring	5
Bivariate copula regression models for semi-competing risks	5
Augmented two-stage estimation for treatment switching in oncology trials: Leveraging external data for improved precision	5
Unbiased and robust analysis of co-localization in super-resolution images	5
Bayesian analysis of joint quantile regression for multi-response longitudinal data with application to primary biliary cirrhosis sequential cohort study	5
An objective Bayesian approach to estimation in multistage experiments	5
LASSO-type instrumental variable selection methods with an application to Mendelian randomization	5
Distribution-free control charts for mixed-type data based on rank of interpoint distances	5
Semiparametric generalized estimating equations for repeated measurements in cross-over designs	5
The “Why” behind including “Y” in your imputation model	5
Group lasso priors for Bayesian accelerated failure time models with left-truncated and interval-censored data	5
Health utility adjusted survival: A composite endpoint for clinical trial designs	5
Simulation extrapolation method for measurement error: A review	5
Divided-and-combined omnibus test for genetic association analysis with high-dimensional data	4
Data-driven clustering of infectious disease incidence into age groups	4
Strategies to boost statistical efficiency in randomized oncology trials with primary time-to-event endpoints	4
Measuring the individualization potential of treatment individualization rules: Application to rules built with a new parametric interaction model for parallel-group clinical trials	4
Diagnostic accuracy analysis for multiple raters using probit hierarchical model for ordinal ratings	4
Sample size determination for adaptive crossover trial in detecting gene-drug interactions	4
Simulating time-to-event data subject to competing risks and clustering: A review and synthesis	4
Efficient algorithms for survival data with multiple outcomes using the frailty model	4
Bivariate joint models for survival and change of cognitive function	4
Regularization approaches in clinical biostatistics: A review of methods and their applications	4
Covariate-adjusted inference for doubly adaptive biased coin design	4
Comparisons of various estimates of the I2 statistic for quantifying between-study heterogeneity in meta-analysis	4
Estimating dynamic treatment regimes for ordinal outcomes with household interference: Application in household smoking cessation	4
Jointly assessing multiple endpoints in pilot and feasibility studies	4
Graphical methods to illustrate the nature of the relation between a continuous variable and the outcome when using restricted cubic splines with a Cox proportional hazards model	4
Methods for comparative effectiveness based on time to confirmed disability progression with irregular observations in multiple sclerosis	4
Causal rule ensemble method for estimating heterogeneous treatment effect with consideration of prognostic effects	4
An overview of optimal designs under a given budget in cluster randomized trials with a binary outcome	4
Average treatment effect on the treated, under lack of positivity	4
A comparison of various aggregation functions in multi-criteria decision analysis for drug benefit–risk assessment	4
Efficient estimation of the marginal mean of recurrent events in randomized controlled trials	4
Using inverse probability of censoring weighting to estimate hypothetical estimands in clinical trials: Should we implement stabilisation, and if so how?	4
Biomarker-driven optimal designs for patient enrollment restriction	4
Extended excess hazard models for spatially dependent survival data	4
Model detection for semiparametric accelerated failure additive model with right-censored data	3
Integrating relative survival in multi-state models—a non-parametric approach	3
Weighting methods for truncation by death in cluster-randomized trials	3
Online control of the False Discovery Rate in group-sequential platform trials	3
Variable selection for mixed panel count data under the proportional mean model	3
Wilcoxon rank-sum tests to detect one-sided mixture alternatives in group sequential clinical trials	3
A statistical framework for planning and analysing test–retest studies of repeatability	3
A robust Bayesian dose optimization design with backfill and randomization for phase I/II clinical trials	3
A natural history and copula-based joint model for regional and distant breast cancer metastasis	3
Youden index estimation based on group-tested data	3
Uniformization and bounded Taylor series in Newton–Raphson method improves computational performance for a multistate transition model estimation and inference	3
Paired count regressions for modeling the number of doctor consultations and non-prescribed drugs intake	3
Multivariate contaminated normal linear mixed models applied to Alzheimer’s disease study with censored and missing data	3

Semi-parametric testing for ordinal treatment effects in time-to-event data via dynamic Dirichlet process mixtures of the inverse-Gaussian distribution	3
Improving estimation efficiency of case-cohort studies with interval-censored failure time data	3
Authors’ response	3
On the estimation of population size—A comparison of capture-recapture and multiplier-benchmark methods	3
On estimating a constrained bivariate random effects model for meta-analysis of test accuracy studies	3
A Bayesian hierarchical model for the analysis of visual analogue scaling tasks	3
Multicategory matched learning for estimating optimal individualized treatment rules in observational studies with application to a hepatocellular carcinoma study	3
Bayesian semiparametric joint modeling of a count outcome and inconveniently timed longitudinal predictors	3
Does it decay? Obtaining decaying correlation parameter values from previously analysed cluster randomised trials	3
Optimising error rates in programmes of pilot and definitive trials using Bayesian statistical decision theory	3
Cross-validation approaches for penalized Cox regression	3
Informative simultaneous confidence intervals for graphical test procedures	3
Fitting to the UK COVID-19 outbreak, short-term forecasts and estimating the reproductive number	3
Using information criteria to select smoothing parameters when analyzing survival data with time-varying coefficient hazard models	3
A distribution-free smoothed combination method to improve discrimination accuracy in multi-category classification	3
Response adaptive randomisation in clinical trials: Current practice, gaps and future directions	3
Modified interactive Q-learning for attenuating the impact of model misspecification with treatment effect heterogeneity	3
Adaptive aggregation for longitudinal quantile regression based on censored history process	3
Intervention treatment distributions that depend on the observed treatment process and model double robustness in causal survival analysis	3
Exponentially weighed moving average charts for monitoring zero-inflated proportions with applications in health care	3
Comparison of random forest methods for conditional average treatment effect estimation with a continuous treatment	3
Nonparametric Bayesian functional selection in 1-M matched case-crossover studies	3
Assessing spillover effects: Handling missing outcomes in network-based studies	3
Isotonic design for single-arm biomarker stratified trials	3
Nonparametric Bayesian Q-learning for optimization of dynamic treatment regimes in the presence of partial compliance	2
Bayesian tensor logistic regression with applications to neuroimaging data analysis of Alzheimer’s disease	2
ROSIE: RObust Sparse ensemble for outlIEr detection and gene selection in cancer omics data	2
Proportion of treatment effect explained: An overview of interpretations	2
The augmented synthetic control method in public health and biomedical research	2
Partial areas under the curve of the cumulative distribution function as a new composite estimand for randomized clinical trials	2
Estimation of the average treatment effect with variable selection and measurement error simultaneously addressed for potential confounders	2
A jackknife approach to estimate the prediction uncertainty from binary classifiers under right-censoring	2
Dynamic prediction by landmarking with data from cohort subsampling designs	2
An efficient approach for optimizing the cost-effective individualized treatment rule using conditional random forest	2
Data-dependent early completion of dose-finding trials for drug-combination	2
Refined moderation analysis with binary outcomes in precision medicine research	2
A model-based approach for historical borrowing, with an application to neovascular age-related macular degeneration	2
Saddlepoint approximation p-values of weighted log-rank tests based on censored clustered data under block Efron’s biased-coin design	2
Conversion of non-inferiority margin from hazard ratio to restricted mean survival time difference using data from multiple historical trials	2
Estimating latent, dynamic processes of breast cancer tumour growth and distant metastatic spread from mammography screening data	2
Compositional functional regression and isotemporal substitution analysis: Methods and application in time-use epidemiology	2
Estimating transformations for evaluating diagnostic tests with covariate adjustment	2
The performance of marginal structural models for estimating risk differences and relative risks using weighted univariate generalized linear models	2
Smoothed simulated pseudo-maximum likelihood estimation for nonlinear mixed effects models with censored responses	2
Comparative study of Bayesian and frequentist methods for epidemic forecasting: Insights from simulated and historical data	2
Design of egocentric network-based studies to estimate causal effects under interference	2
Methods for non-proportional hazards in clinical trials: A systematic review	2
Statistical assessment of biomarker replicability using MAJAR method	2
Rank-based estimators of global treatment effects for cluster randomized trials with multiple endpoints on different scales	2
Survival analysis with a random change-point	2
On estimating the area under the ROC curve in ranked set sampling	2
Estimation of global average treatment effect in National Heart, Lung, and Blood Institute (NHLBI) Growth and Health Study	2
Permutation tests for detecting treatment effect heterogeneity in cluster randomized trials	2
A family of estimators to diagnostic accuracy when candidate tests are subject to detection limits—Application to diagnosing early stage Alzheimer disease	2
Permutation-based global rank test with adaptive weights for multiple primary endpoints	2
On identification and estimation for sufficient cause interaction through a quasi-instrumental variable	2
Propensity score weighting methods for causal subgroup analysis with time-to-event outcomes	2
Logistic regression with correlated measurement error and misclassification in covariates	2
Dirichlet process mixture models for regression discontinuity designs	2
Instrumental variable analysis with categorical treatment	2
A matching-based machine learning approach to estimating optimal dynamic treatment regimes with time-to-event outcomes	2
Matching ratio and sample size for optimal sequential testing with binomial data	2
Doubly-robust estimator of the difference in restricted mean times lost with competing risks data	2
Marginal semiparametric accelerated failure time cure model for clustered survival data	2
Boosting distributional copula regression for bivariate binary, discrete and mixed responses	2
Cure models with adaptive activation for modeling cancer survival	2
Partly linear single-index cure models with a nonparametric incidence link function	2
Outcome adaptive propensity score methods for handling censoring and high-dimensionality: Application to insurance claims	2
Model-based approach for two-stage group sequential or adaptive designs in bioequivalence studies using parallel and crossover designs	2
Two-stage subsampling variable selection for sparse high-dimensional generalized linear models	2
Two-stage Bayesian network meta-analysis of individualized treatment rules for multiple treatments with siloed data	2
Multiple imputation for cause-specific Cox models: Assessing methods for estimation and prediction	2
Sample size estimation for comparing dynamic treatment regimens in a SMART: A Monte Carlo-based approach and case study with longitudinal overdispersed count outcomes	2
Penalized estimation for varying coefficient additive hazards models	2
Application of marginalized zero-inflated models when mediators have excess zeroes	2
Additive hazard causal model with a binary instrumental variable	2
Bayesian multiple Gaussian graphical models for multilevel variables from unknown classes	2
Modeling rounded counts using a zero-inflated mixture of power series family of distributions	2
Hierarchical Bayesian bivariate spatial modeling of small area proportions with application to health survey data	2
Predictive abilities comparison from multiple dynamic prediction models	2
Variable selection using inverse probability of censoring weighting	2
Group sequential methods based on supremum logrank statistics under proportional and nonproportional hazards	2
An overview of propensity score matching methods for clustered data	2
Causal mediation analysis with multiple causally non-ordered and ordered mediators based on summarized genetic data	2
Joint regression analysis of clustered current status data with latent variables	2
Determination of correlations in multivariate count data with informative observation times	2
A novel rare variants association test for binary traits in family-based designs via copulas	2
A novel power prior approach for borrowing historical control data in clinical trials	2
Unit information prior for incorporating real-world evidence into randomized controlled trials	2
Point estimation of the 100p percent lethal dose using a novel penalised likelihood approach	2
On prior smoothing with discrete spatial data in the context of disease mapping	2
Multivariate control charts for monitoring a bivariate correlated count process with application to meningococcal disease	2
A note on response-adaptive randomization from a Bayesian prediction viewpoint	2
Using joint models for longitudinal and time-to-event data to investigate the causal effect of salvage therapy after prostatectomy	2
Joint modelling of longitudinal ordinal and multi-state data	2