OOIR: Observatory of International Research

Papers

(The H4-Index of Protein Science is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
	2048
	1425
Rapid directed molecular evolution of fluorescent proteins in mammalian cells	553
Design of an effective small expression tag to enhance GPCR production in E. coli‐based cell‐free and whole cell expression systems	442
Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains	270
Molecular mechanism of Fe³⁺ binding inhibition to Vibrio metschnikovii ferric ion‐binding protein, FbpA, by rosmarinic acid and its hydrolysate, danshensu	257
Structural and functional validation of a highly specific Smurf2 inhibitor	240
Helicobacter pylori FlgN binds its substrate FlgK and the flagellum ATPase FliI in a similar manner observed for the FliT chaperone	230
Similar protein segments shared between domains of different evolutionary lineages	151
Contributions of the N‐terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA‐induced phase separation	139
Solution structure of the Z0 domain from transcription repressor BCL11A sheds light on the sequence properties of protein‐binding zinc fingers	136
Fine‐tuned interactions between globular and disordered regions of single‐stranded DNA binding (SSB) protein are required for dynamic condensation under physiological conditions	134
CSM‐peptides: A computational approach to rapid identification of therapeutic peptides	109
Epitope‐directed anti‐SARS‐CoV‐2 scFv engineered against the key spike protein region could block membrane fusion	102
Effects of N‐ and C‐terminal regions on oligomeric formation of blue light sensor protein SyPixD	100
Substrate binding in the allosteric site mimics homotropic cooperativity in the SIS‐fold glucosamine‐6‐phosphate deaminases	99
Structural polymorphism and cytotoxicity of brain‐derived β‐amyloid extracts	82
Issue information	82
Evolution of affinity between p53 transactivation domain and MDM2 across the animal kingdom demonstrates high plasticity of motif‐mediated interactions	72
BEAN and HABAS: Polyphyletic insertions in the DNA‐directed RNA polymerase	69
Xplor‐NIH: Better parameters and protocols for NMR protein structure determination	68
The Phenix‐AlphaFold webservice: Enabling AlphaFold predictions for use in Phenix	65
Biophysical insights into the dimer formation of human Sirtuin 2	65
CsgA gatekeeper residues control nucleation but not stability of functional amyloid	60
Biophysical characterization of RelA–p52 NF‐κB dimer—A link between the canonical and the non‐canonical NF‐κB pathway	59

Gating residues govern ligand unbinding kinetics from the buried cavity in HIF‐2α PAS‐B	56
Structure–function mapping and mechanistic insights on the SARS CoV2 Nsp1	50
A novel method for expressing and purifying large quantities of functional and stable human voltage‐gated proton channel (hH_v1)	46
Impact of local unfolding fluctuations on the evolution of regional sequence preferences in proteins	44
Cover Image	40
Torsional twist of the SARS‐CoV and SARS‐CoV‐2 SUD‐N and SUD‐M domains	40
Extrinsic and intrinsic factors affect copper‐induced protein precipitation across eukaryotic and prokaryotic proteomes	40
Structural hierarchy of mechanical extensibility in human von Willebrand factor multimers	39
Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation	39
An ankyrin repeat chaperone targets toxic oligomers during amyloidogenesis	38
Two residues determine nicotinic acetylcholine receptor requirement for RIC‐3	37
Soluble SARS‐CoV‐2 RBD and human ACE2 peptidase domain produced in DrosophilaS2 cells show functions evoking virus–cell interface	37