Bioorganic & Medicinal Chemistry Letters

Article	Citations
Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines	151
Discovery of quinuclidine modulators of cellular progranulin	85
Discovery of N-(6-(5-fluoro-2-(piperidin-1-yl)phenyl)pyridazin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)methanesulfonamide as a brain-permeable and metabolically stable kynurenine monooxygenase inhibitor	72
Design and structural optimization of thiadiazole derivatives with potent GLS1 inhibitory activity	66
Design, synthesis and biological evaluation of alginate oligosaccharide derivatives	64
Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site	52
The ester derivatives obtained by C-ring modification of podophyllotoxin induce apoptosis and inhibited proliferation in PC-3M cells via down-regulation of PI3K/Akt signaling pathway	52
Design, synthesis and biological evaluation of tanshinone IIA derivatives as NLRP3 inflammasome inhibitors	51
Enteroviral replication inhibition by N-Alkyl triazolopyrimidinone derivatives through a non-capsid binding mode	44
Neuropilin 1-targeted near-infrared fluorescence probes for tumor diagnosis	41
Development of a highly potent and selective degrader of LRRK2	41
Revisiting the dipeptidyl carboxypeptidase inhibitor captopril as a source of pan anti-trypanosomatid agents	39
Novel carbohydrate-based sulfonamide derivatives as selective carbonic anhydrase II inhibitors: Synthesis, biological and molecular docking analysis	36
Phytochemical investigation of Asarum sieboldii var. seoulense and the phenotypic profiles of its constituents against a Parkinson’s Disease olfactory cell line	36
Synthesis and characterization of chiral 6-azaspiro[2.5]octanes as potent and selective antagonists of the M4 muscarinic acetylcholine receptor	35
Pyrazolo-1-carbothioamides as EGR-1–DNA binding disruptors	35
Armeniaspirol analogues disrupt the electrical potential (ΔΨ) of the proton motive force	34
Editorial Board	34
Synthesis and SAR of novel GPR39 agonists and positive allosteric modulators	33
Design of 99mTc-labeled zinc-chelating imaging probe for SPECT imaging of the pancreas	32
Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model	31
Graphical Abstract TOC	30
SARS-CoV-2 papain-like protease (PLpro) inhibitory and antiviral activity of small molecule derivatives for drug leads	30
Studies on in vitro modulatory effects to base excision repair enzymes induced by small molecule binding to Deaminated CAG repeat hairpin	30
Design, synthesis and characterizations of prodrugs of brexanolone	29

Discovery of 3-amino-4-{(3S)-3-[(2-ethoxyethoxy)methyl]piperidin-1-yl}thieno[2,3-b]pyridine-2-carboxamide (DS96432529): A potent and orally active bone anabolic agent	29
Editorial Board	29
Non-alkylator anti-glioblastoma agents induced cell cycle G2/M arrest and apoptosis: Design, in silico physicochemical and SAR studies of 2-aminoquinoline-3-carboxamides	28
Green synthesis and anti-biofilm activities of 3,5-disubstituted isoxazoline/isoxazole-linked secondary sulfonamide derivatives on Pseudomonas aeruginosa	28
Editorial Board	28
Discovery of DS-1093a: An oral hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of renal anemia	27
New class of fused [3,2-b][1,2,4]triazolothiazoles for targeting glioma in vitro	27
Novel molecule combinations and corresponding hybrids targeting artemisinin-resistant Plasmodium falciparum parasites	26
Discovery of novel iminosydnone compounds with insecticidal activities based on the binding mode of triflumezopyrim	26
A fluorescent molecular rotor for the selective detection of the hybrid-conformation 22AG G-Quadruplex	26
A PSMA-targeted doxorubicin small-molecule drug conjugate	25
Improved synthesis and anticancer activity of a potent neuronal nitric oxide synthase inhibitor	25
Design, synthesis, biological evaluation and molecular modeling of N-isobutyl-N-((2-(p-tolyloxymethyl)thiazol-4yl)methyl)benzo[d][1,3] dioxole-5-carboxamides as selective butyrylcholinesterase inhibit	25
Microwave assisted regioselective synthesis of quinoline appended triazoles as potent anti-tubercular and antifungal agents via copper (I) catalyzed cycloaddition	24
Epigallocatechin and epigallocatechin-3-gallate are not inhibitors of tyrosinase	23
Design and evaluation of anaplastic lymphoma kinase degraders using a covalent fumarate handle	22
A simple yet multifaceted 90 years old, evergreen enzyme: Carbonic anhydrase, its inhibition and activation	22
Contents continued	21
Synthesis and biological evaluation of novel 1,2,3,4-tetrahydro-β-carboline derivatives as potential antibacterial agents	21
Selective formation of a phenathridine derivative by photodegradation of azilsartan	21
New bis- and tetrakis-1,2,3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants	21
Contents continued	21
Exploratory study of oxatomide derivatives with high P2X7 receptor inhibitory activity	20
Discovery of arylsulfonamides as a novel class of allosteric integrase inhibitors with antiviral activity	20
Editorial Board	20
Graphical abstract TOC	20
Pharmacokinetic analysis of 6-O-[18F]FEE for PET imaging of EGFR mutation	20
Design, synthesis and biological evaluation of pyrimidine base hydroxamic acid derivatives as dual JMJD3 and HDAC inhibitors	19
DDD-028: A potent, neuroprotective, non-opioid compound for the treatment of diabetic neuropathy	19
pH-responsive aggregates consisted of oligodeoxynucleotides bearing nitrophenol group that deliver drugs into acidic cells	19
Graphical abstract TOC	19
Graphical abstract TOC	19
Graphical abstract TOC	18
Discovery and optimization of (2-naphthylthio)acetic acid derivative as selective Bfl-1 inhibitor	18
Synthesis and evaluation of lipoic acid – donepezil hybrids for Alzheimer’s disease using a straightforward strategy	18
Addition of hydrophobic side chains improve the apoptosis inducibility of the human glyoxalase I inhibitor, TLSC702	18
Optimisation of momelotinib with improved potency and efficacy as pan-JAK inhibitor	18
High-yield and high-purity amide bond formation using DMTMM PF6 for DNA-encoded libraries	18
Design, synthesis and biological evaluation of pteridine-7(8H)-one derivatives as potent and selective CDK4/6 inhibitors	18
α-Fluorination of tropane compounds and its impact on physicochemical and ADME properties	18
Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships	18
Graphical abstract TOC	18
A photoactivatable self-localizing ligand with improved photosensitivity for chemo-optogenetic control of protein localization in living cells	18
New class of hantaan virus inhibitors based on conjugation of the isoindole fragment to (+)-camphor or (−)-fenchone hydrazonesv	18
Design, synthesis, and biological evaluation of 5ʹ-deoxy (N)-methanocarbanucleoside derivatives as A3 adenosine receptor ligands	17
Design and discovery of C2-fluoroalkyl iminothiazine dioxides as BACE inhibitors	17
Identification and evaluation of 4-anilinoquin(az)olines as potent inhibitors of both dengue virus (DENV) and Venezuelan equine encephalitis virus (VEEV)	17
Synthesis and biological evaluation of naphthoquinone phenacylimidazolium derivatives	17
Photocrosslinking and capture for the analysis of carbohydrate-dependent interactions	17
Retraction notice to “Preclinical metabolism of LB42908, a novel farnesyl transferase inhibitor, and its effects on the cytochrome P450 isozyme activities” [Bioorg. Med. Chem. Lett. 22(9) (2012) 3067–	17

Comparative analysis of p-terphenylquinone and seriniquinone derivatives as reactive oxygen species-modulating agents	17
Design and activity evaluation of new EGFR tyrosine kinase inhibitors containing cyclic polyamines	17
Novel pyridinium-type fullerene derivatives as multitargeting inhibitors of HIV-1 reverse transcriptase, HIV-1 protease, and HCV NS5B polymerase	16
Contents continued	16
Rational design, synthesis and biological evaluation of novel HIV-1 protease inhibitors containing 2-phenylacetamide derivatives as P2 ligands with potent activity against DRV-Resistant HIV-1 variants	16
Design, synthesis and biological evaluation of novel procaine derivatives for intravenous anesthesia	16
Evaluation of the antiproliferative activity of 106 marine microbial metabolites against human lung cancer cells and potential antiproliferative mechanism of purpuride G	16
Biocatalytic synthesis and evaluation of antioxidant and antibacterial activities of hydroxyequols	16
Synthesis and evaluation of 3-hydroxyquinolin-2(1H)-one derivatives as inhibitors of tyrosinase	16
Design, synthesis and properties of peptide inhibitors based on BRCA1856-871	16
nTZDpa (non-thiazolidinedione PPARγ partial agonist) derivatives retain antimicrobial activity without improving renal toxicity	16
Ultrasound-dependent RNAi using TatU1A-rose bengal conjugate	15
Design, synthesis and biological evaluation of novel cyano-cinnamate derivatives as mitochondrial pyruvate carrier inhibitors	15
Design and synthesis of novel fluorene derivatives as inhibitors of pyruvate dehydrogenase kinase	15
Synthesis and evaluation of potent novel inhibitors of human sulfide:quinone oxidoreductase	15
Potent and selective carbonic anhydrase inhibition activities of pyrazolones bearing benzenesulfonamides	15
An overview of cyclopropenone derivatives as promising bioactive molecules	15
PEG-lipid-modified agonistic antibody against tumor necrosis factor receptor family elicits superior apoptosis-inducing activity against human carcinoma	15
Design, synthesis and biological evaluation of novel cationic liposomes loaded with melphalan for the treatment of cancer	15
Syntheses and antitumor activities of neorautenol and shinpterocarpin analogs	15
Synthesis and pharmacological characterization of multiply substituted 2H-chromene derivatives as P2Y6 receptor antagonists	15
Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious PERK kinase inhibitors	15
Biological evaluation of newly synthesized α-benzil monoxime thiocarbohydrazide derivatives as an antimicrobial and anticancer agent: In vitro screening and ADMET predictions	15
Tryptophan derivatives regulate the seed germination and radicle growth of a root parasitic plant, Orobanche minor	15
Stereochemical inversion at a 1,4-cyclohexyl PROTAC linker fine-tunes conformation and binding affinity	15
Antibacterial activity of β-sitosterol isolated from the leaves of Odontonema strictum (Acanthaceae)	15
A dual aurora and lim kinase inhibitor reduces glioblastoma proliferation and invasion	14
6-Aryl-quinazolines as novel GABAB receptor positive allosteric modulators	14
Identification of potent and selective inhibitors of PKR via virtual screening and traditional design	14
Improving reactivity of naphthalimide-based GST probe by imparting TPP cation: Development and application for live cell imaging	14
Structure-activity relationship of dibenzylideneacetone analogs against the neglected disease pathogen, Trypanosoma brucei	14
Design, synthesis and activity evaluation of Hedgehog inhibitor Itraconazole derivatives in A549 cells	14
Synthesis and biological evaluation of substituted amide derivatives of C4-ageratochromene dimer analog	14
(E)-3-(3-([1,1′-Biphenyl]-4-yl)-1-phenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-ones inducing reactive oxygen species generation through glutathione depletion	14
Insecticidal activity of twin compounds from podophyllotoxin and cytisine	14
Design and synthesis of a series of OFF-ON near infrared fluorescent probes for nucleic acid in aqueous solution	14
Synthesis of a tricyclic hexapeptide –via two consecutive ruthenium-catalyzed macrocyclization steps– with a constrained topology to mimic vancomycin's binding properties toward D-Ala-D-Ala dipeptide	14
Inhibitors of heat shock protein 70 (Hsp70) with enhanced metabolic stability reduce tau levels	14
Design, synthesis, in silico studies, and antiproliferative evaluations of novel indolin-2-one derivatives containing 3-hydroxy-4-pyridinone fragment	14
Synthesis of a new series of quinoline/pyridine indole-3-sulfonamide hybrids as selective carbonic anhydrase IX inhibitors	13
Discovery of triazenyl triazoles as Nav1.1 channel blockers for treatment of epilepsy	13
Reinvestigation of clopidogrel bioactivation unveils new cytochrome P450-catalyzed thioester cleavage mechanism	13
Direct-to-biology platform: From synthesis to biological evaluation of SHP2 allosteric inhibitors	13
Graphical Abstract Contents Continued	13
Contents continued	13
Structure–activity relationship of 2-aminodibenzothiophene pharmacophore and the discovery of aminobenzothiophenes as potent inhibitors of Mycobacterium smegmatis	13
Graphical abstract TOC	13
Editorial Board	13
Graphical abstract TOC	13
Rationalizing the binding and α subtype selectivity of synthesized imidazodiazepines and benzodiazepines at GABAA receptors by using molecular docking studies	13
Discovery of dronedarone and its analogues as NLRP3 inflammasome inhibitors with potent anti-inflammation activity	13
Editorial Board	13
Design, synthesis and biological evaluation of cajanonic acid A analogues as potent PPAR γ antagonists	13
Graphical abstract TOC	13
Graphical Abstract Continued	13
Editorial Board	13
Neratinib derivative 7A induces apoptosis in colon cancer cells via the p53 pathway	13
Discovery of novel N-(1-benzyl-1H-imidazol-2-yl)amide derivatives as melanocortin 1 receptor agonists	13
Editorial Board	12
Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor	12
LncRNA SNHG6 accelerates nasopharyngeal carcinoma progression via modulating miR-26a-5p/ARPP19 axis	12
Attachment of cyclodextrin acids to PEGA resin and study of binding with fluorescence microscopy	12
Discovery of sinomenine/8-Bis(benzylthio)octanoic acid hybrids as potential anti-leukemia drug candidate via mitochondrial pathway	12
Design, synthesis, and biological evaluation of polyphenol derivatives as DYRK1A inhibitors. The discovery of a potentially promising treatment for Multiple Sclerosis	12
Synthesis of dolutegravir derivatives modified by 1,2,3-triazole structure and their anti-inflammatory activity in LPS-induced BV2 cells	12
Graphical abstract TOC	12
Discovery of a potent orally available pyrazolopyridone derivative as a novel selective bromodomain and extra-terminal domain (BET)-first bromodomain (BD1) inhibitor	12
Conversion of oxadiazolo[3,4-b]pyrazines to imidazo[4,5-b]pyrazines via a tandem reduction-cyclization sequence generates new mitochondrial uncouplers	12
Hydrazinecarbonyl-thiazol-2-acetamides with pronounced apoptotic behavior: synthesis, in vitro/in vivo anti-proliferative activity and molecular modeling simulations	12
Graphical abstract TOC	12
Investigation of the site 2 pocket of Grp94 with KUNG65 benzamide derivatives	12
Structure-activity relationship of dual inhibitors containing maleimide and imidazole motifs against glutaminyl cyclase and glycogen synthase kinase-3β	12
Novel trifluoromethyl sydnone derivatives: Design, synthesis and fungicidal activity	12
SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors	12
Contents continued	12
PSMA-targeted SMART molecules outfitted with SN38	12
Content continued	12
Synthesis and anti-proliferation activity of mogrol derivatives bearing quinoline and triazole moieties	12
A unified “top-down” approach for the synthesis of diverse lead-like molecular scaffolds	12
Graphical abstract TOC	12

Enzymatic reconstitution of salicylate formation in promysalin biosynthesis	12
A turn-on fluorescent PCNA sensor	12
Corrigendum to “Discovery of 4-aminopyrimidine analogs as highly potent dual P70S6K/Akt inhibitors” [Bioorgan. Med. Chem. Lett. 50 (2021) 128352]	12
Graphical abstract TOC	12
Development of novel GI-centric prostaglandin E2 receptor type 4 (EP4) agonist prodrugs as treatment for ulcerative colitis and other intestinal inflammatory diseases	11
Synthesis and evaluation of antimycobacterial activity of riboflavin derivatives	11
Cyano-Hydrol green derivatives: Expanding the 9-cyanopyronin-based resonance Raman vibrational palette	11
Design and identification of a new farnesoid X receptor (FXR) partial agonist by computational structure–activity relationship analysis: Ligand-induced H8 helix fluctuation in the ligand-binding domai	11
Discovery of 3,6-disubstutited-imidazo[1,2-a]pyridine derivatives as a new class of CLK1 inhibitors	11
Synthesis and biological evaluation of biotinylated ZJ-101	11
A guanidinium group is an effective mimic of the tertiary carbocation formed by isopentenyl diphosphate isomerase	11
Synthesis, in vitro cytotoxicity evaluation and mechanism of 5′ monosubstituted chalcone derivatives as antitumor agents	11
Discovery of a proteolysis targeting chimera (PROTAC) as a potent regulator of FOXP3	11
Discovery of 3-acyl-2-anilino-1,4-dihydroquinolin-4-one derivatives as potential inhibitors of methicillin-resistant Staphylococcus aureus	11
Synthesis of mizoribine prodrugs and their in vivo evaluation as immunosuppressive agents	11
Highly potent anti-inflammatory, analgesic and antioxidant activities of 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine thiones	11
Graphical abstract TOC	11
Harnessing dual-mode RIPK1 ligands for cross-species anti-necroptosis inhibitor compounds	11
Imidazo[2,1-b]thiazole based indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor: Structure based design, synthesis, bio-evaluation and docking studies	11
Photo-regulated PROTACs: A novel tool for temporal control of targeted protein degradation	11
Design, synthesis and biological evaluation of novel indole-piperazine derivatives as antibacterial agents	11
Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome	11
Methyl N-(tert-butoxycarbonyl)pyridine-2-carbimidothioate: A new reagent for the synthesis of N-phenylpyridinecarboxamidine (“arylimidamide”) DNA-minor groove binders from poorly nucleophilic amines	11
Contents continued	11
Synthesis and biological activity of conformationally restricted indole-based inhibitors of neurotropic alphavirus replication: Generation of a three-dimensional pharmacophore	11
Graphical abstract TOC	11
A small molecule binding to TGGAA pentanucleotide repeats that cause spinocerebellar ataxia type 31	11
Discovery of an ellipticine derivative as TLR3 inhibitor against influenza A virus and SARS-CoV-2	11
Permeation behavior of porphyrin derivatives with different functional group positions across cancer cell membranes	11
Graphical Abstract TOC	10
Novel drug discovery approaches for MMP-13 inhibitors in the treatment of osteoarthritis	10
Synthesis of esters and amides of 2-aryl-1-hydroxy-4-methyl-1H-imidazole-5-carboxylic acids and study of their antiviral activity against orthopoxviruses	10
Discovery of a potent and subtype-selective TYK2 degrader based on an allosteric TYK2 inhibitor	10
Designing a novel photoinduced electron transfer-based small-molecule fluorescent probe specific for CYP3A isozymes	10
Evaluation of an ester-linked immunosuppressive payload: A case study in understanding the stability and cleavability of ester-containing ADC linkers	10
Discovery of acyl ureas as highly selective small molecule CSF1R kinase inhibitors	10
Graphical abstract TOC	10
Novel imidazo[1,5-a]quinoxaline derivatives: SAR, selectivity and modeling challenges en route to the identification of an α5-GABAA receptor NAM	10
Graphical abstract TOC	10
Zinc-dependent deacetylases (HDACs) as potential targets for treating Alzheimer’s disease	10
New diarylpentanoids and chalcones as potential antimicrobial adjuvants	10
PES derivative PESA is a potent tool to globally profile cellular targets of PES	10
Circular dichroism spectroscopy of DNA duplexes at near-biological concentrations	10
Graphical Abstract Contents Continued	10
Editorial Board	10
Retraction notice to “Synthesis and bioevaluation of aryl-guanidino polyamine conjugates targeting the polyamine transporter” [Bioorg. Med. Chem. Lett. 20 (2010) 6421–6425]	10
Contents continued	10
Graphical abstract TOC	10
Further structural optimization and SAR study of sungsanpin derivatives as cell-invasion inhibitors	10
Synthesis, modeling, and biological evaluation of anti-tubulin indole-substituted furanones	10
Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability	10
Iodophenyl-conjugated closo-dodecaborate as a promising small boron molecule that binds to serum albumin and accumulates in tumor	10
Design, synthesis and in-vitro evaluation of fluorinated triazoles as multi-target directed ligands for Alzheimer disease	10
Design of cyclic peptides as novel inhibitors of ICOS/ICOSL interaction	10
Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold	10
Graphical Abstract TOC	10
Development of chromone-thiazolidine-2,4-dione Knoevenagel conjugates as apoptosis inducing agents	9
4-Oxooctahydroquinoline-1(2H)-carboxamides as hepatitis B virus (HBV) capsid core protein assembly modulators	9
SAR study of niclosamide derivatives for neuroprotective function in SH-SY5Y neuroblastoma	9
Discovery of aryl aminothiazole γ-secretase modulators with novel effects on amyloid β-peptide production	9
Contents continued	9
Huprine Y – Tryptophan heterodimers with potential implication to Alzheimer’s disease treatment	9
Synthesis and antitumor activity of a series of novel N-aryl-5-(2,2,2-trifluoroethoxy)-1,5-dihydro-2H-pyrrol-2-ones derivatives	9
Editorial Board	9
Pyrimidine-2,4-dione targets STAT3 signaling pathway to induce cytotoxicity in hepatocellular carcinoma cells	9
Synthesis and anti-fibrotic effects of santamarin derivatives as cytotoxic agents against hepatic stellate cell line LX2	9
Discovery of a DCAF11-dependent cyanoacrylamide-containing covalent degrader of BET-proteins	9
Synthesis and preliminary immunologic properties of di-/trisaccharide-conjugates related to Bacillus anthracis	9
An ascidian Polycarpa aurata-derived pan-inhibitor against coronaviruses targeting Mpro	9
Synthesis of drimanyl indole fragments of drimentine alkaloids and their antibacterial activities	9
Identification of Plasmodium falciparum falcilysin inhibitors by a virtual screen	9
Design, synthesis, and biological evaluation of novel HDAC inhibitors with a 3-(benzazol-2-yl)quinoxaline framework	9
Antibacterial activity of noscapine analogs	9
Design, synthesis and antitumor activity of novel 4-oxobutanamide derivatives	9
Synthesis, biological evaluation, and correlation of cytotoxicity versus redox potential of 1,4-naphthoquinone derivatives	9
Synthesis of proposed structure of ledebourin A	9
Exploration of inhibitors of the bacterial LexA repressor-protease	9
Design, synthesis and biological evaluation of a series of iron and copper chelating deferiprone derivatives as new agents active against Candida albicans	9
Activation of 8–17 DNAzyme with extra functional group at conserved residues is related to catalytic metal ion	9
Design, synthesis and evaluation of the Brigatinib analogues as potent inhibitors against tertiary EGFR mutants (EGFRdel19/T790M/C797S and EGFRL858R/T790M/C797S)	9
Structure activity relationship of 3-nitro-2-(trifluoromethyl)-2H-chromene derivatives as P2Y6 receptor antagonists	9
Design and synthesis of novel orexin 2 receptor agonists based on naphthalene skeleton	9
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity	9
Structural simplification of evodiamine: Discovery of novel tetrahydro-β-carboline derivatives as potent antitumor agents	9
The structural modification and biological evaluation of tetrahydrothienopyridine derivatives as selective BChE inhibitors	9
A FOXC2 inhibitor, MC-1-F2, as a therapeutic candidate for targeting EMT in castration-resistant prostate cancer	9
The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding	9
Diamino variants of piperazine-based tissue transglutaminase inhibitors	9
Synthesis and properties of PNA containing a dicationic nucleobase based on N4-benzoylated cytosine	9
Multigram-scale total synthesis of (±)-ambreinolide by a diastereoselective polyene cyclization	9
Design, synthesis and biological evaluation of sulfonylurea derivatives as NLRP3 inflammasome inhibitors	9
Thiamine analogues featuring amino-oxetanes as potent and selective inhibitors of pyruvate dehydrogenase	9
Design, synthesis and antiproliferative activity of novel 2,4-diamino-5-methyleneaminopyrimidine derivatives as potential anticancer agents	9
The lipidation and glycosylation enabling bioactivity enhancement and structural change of antibacterial peptide G3	9
Short synthesis of a broadly Reactive, cell permeable serine hydrolase Fluorophosphonate-Alkyne probe	9