OOIR: Observatory of International Research

Papers

(The H4-Index of Bioorganic & Medicinal Chemistry Letters is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir	139
Pyridones in drug discovery: Recent advances	82
Structural hybridization as a facile approach to new drug candidates	72
Discovery of a novel series of substituted quinolines acting as anticancer agents and selective EGFR blocker: Molecular docking study	63
1,2,3-triazole-thiazole hybrids: Synthesis, in vitro antimicrobial activity and antibiofilm studies	61
The expanding reaction toolkit for DNA-encoded libraries	59
Design and synthesis, biological evaluation of bis-(1,2,3- and 1,2,4)-triazole derivatives as potential antimicrobial and antifungal agents	58
Recent advances in antibacterial agents	56
Cryo-EM as a powerful tool for drug discovery	56
Synthesis and biological evaluation of anti-tubercular activity of Schiff bases of 2-Amino thiazoles	44
A simple yet multifaceted 90 years old, evergreen enzyme: Carbonic anhydrase, its inhibition and activation	43
Microwave assisted regioselective synthesis of quinoline appended triazoles as potent anti-tubercular and antifungal agents via copper (I) catalyzed cycloaddition	42
A first-in-class clinical G-quadruplex-targeting drug. The bench-to-bedside translation of the fluoroquinolone QQ58 to CX-5461 (Pidnarulex)	42
Click synthesis of 1,2,3-triazole based imidazoles: Antitubercular evaluation, molecular docking and HSA binding studies	41
New bis- and tetrakis-1,2,3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants	41
Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax	37
Structure–activity relationships of GPX4 inhibitor warheads	37
Pyrimidine-conjugated fluoroquinolones as new potential broad-spectrum antibacterial agents	34
Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents	34
Unique para-aminobenzenesulfonyl oxadiazoles as novel structural potential membrane active antibacterial agents towards drug-resistant methicillin resistant Staphylococcus aureus	34
Novel benzothiazole-based dual VEGFR-2/EGFR inhibitors targeting breast and liver cancers: Synthesis, cytotoxic activity, QSAR and molecular docking studies	32
Fused benzo[1,3]thiazine-1,2,3-triazole hybrids: Microwave-assisted one-pot synthesis, in vitro antibacterial, antibiofilm, and in silico ADME studies	31
Exploring the potential of novel phenolic compounds as potential therapeutic candidates against SARS-CoV-2, using quantum chemistry, molecular docking and dynamic studies	31
Ibrexafungerp: An orally active β-1,3-glucan synthesis inhibitor	30
Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors	30

Synthesis and antifungal activity of new hybrids thiazolo[4,5-d]pyrimidines with (1H-1,2,4)triazole	29
Neurotrophic isoindolinones from the fruiting bodies of Hericium erinaceus	28
Chemical update on the potential for serotonin 5-HT6 and 5-HT7 receptor agents in the treatment of Alzheimer’s disease	27