Cell Proliferation

Article	Citations
	259
Osteoblasts impair cholesterol synthesis in chondrocytes via Notch1 signalling	209
Dynamic immune cell profiling identified natural killer cell shift as the key event in early allograft dysfunction after liver transplantation	181
Proteome analysis develops novel plasma proteins classifier in predicting the mortality of COVID‐19	160
Rack1‐mediated ferroptosis affects hindgut development in rats with anorectal malformations: Spatial transcriptome insights	131
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Transplantation of Wnt4‐modified neural stem cells mediate M2 polarization to improve inflammatory micro‐environment of spinal cord injury	82
ZNF281 drives hepatocyte senescence in alcoholic liver disease by reducing HK2‐stabilized PINK1/Parkin‐mediated mitophagy	72
Epidermal growth factor induces a trophectoderm lineage transcriptome resembling that of human embryos during reconstruction of blastoids from extended pluripotent stem cells	72
CD33‐targeting extracellular vesicles deliver antisense oligonucleotides against FLT3‐ITD and miR‐125b for specific treatment of acute myeloid leukaemia	69
TRAPPC2l Participates in Male Germ Cell Development by Regulating Cell Division	65
The beneficial effects of chick embryo extract preconditioning on hair follicle stem cells: A promising strategy to generate Schwann cells	64
Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions	63
A Chemical Reprogramming Approach Efficiently Producing Human Retinal Pigment Epithelium Cells for Retinal Disease Therapies	59
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Mechanisms and therapeutic potential of disulphidptosis in cancer	58
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An aggregation of human embryonic and trophoblast stem cells reveals the role of trophectoderm on epiblast differentiation	48
ISRIB facilitates the co‐culture of human trophoblast stem cells and embryonic stem cells	48
CTCF Point Mutation at R567 Disrupts Mouse Heart Development via 3D Genome Rearrangement and Transcription Dysregulation	47
Liver microphysiological platforms for drug metabolism applications	46
Tetrahedral framework nucleic acids‐based delivery of microRNA‐155 alleviates intervertebral disc degeneration through targeting Bcl‐2/Bax apoptosis pathway	45
Research progress on the hedgehog signalling pathway in regulating bone formation and homeostasis	44

SOX2 plays a crucial role in cell proliferation and lineage segregation during porcine pre‐implantation embryo development	44
Small‐molecule‐driven direct reprogramming of Müller cells into bipolar‐like cells	43
Nivalenol affects Cyclin B1 level and activates SAC for cell cycle progression in mouse oocyte meiosis	42
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AAV‐mediated gene therapy restores natural fertility and improves physical function in the Lhcgr‐deficient mouse model of Leydig cell failure	41
Klotho Regulates Club Cell Senescence and Differentiation in Chronic Obstructive Pulmonary Disease	40
Ciliary IFT‐B Transportation Plays an Important Role in Human Endometrial Receptivity Establishment and is Disrupted in Recurrent Implantation Failure Patients	39
Decoding the Molecular Landscape of Prepubertal Oocyte Maturation: GTPBP4 as a Key Driver of In Vitro Developmental Competence	39
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Self‐assembled human placental model from trophoblast stem cells in a dynamic organ‐on‐a‐chip system	37
Circular RNA hsa_circ_0083756 promotes intervertebral disc degeneration by sponging miR‐558 and regulating TREM1 expression	37
Mitochondrial Calcium uniporters are essential for meiotic progression in mouse oocytes by controlling Ca2+ entry	37
Role of the CCL2‐CCR2 signalling axis in cancer: Mechanisms and therapeutic targeting	36
CircSLC7A2 protects against osteoarthritis through inhibition of the miR‐4498/TIMP3 axis	36
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Platelet‐rich plasma‐derived extracellular vesicles: A superior alternative in regenerative medicine?	35
Piezo1‐mediated M2 macrophage mechanotransduction enhances bone formation through secretion and activation of transforming growth factor‐β1	35
Corrigendum	34
Role of hydrogen sulphide in physiological and pathological angiogenesis	33
Integration of human organoids single‐cell transcriptomic profiles and human genetics repurposes critical cell type‐specific drug targets for severe COVID‐19	33
Velvet antler water extract protects porcine oocytes from lipopolysaccharide‐induced meiotic defects	33
Adult progenitor rejuvenation with embryonic factors	33
Identification of oogonial stem cells in chicken ovary	33
MUSTN1 Interaction With SMPX Regulates Muscle Development and Regeneration	33
Preventing acute liver injury via hepatocyte‐targeting nano‐antioxidants	32
The inhibition of enterocyte proliferation by lithocholic acid exacerbates necrotizing enterocolitis through downregulating the Wnt/β‐catenin signalling pathway	32
Effect of tetrahedral framework nucleic acids on the reconstruction of tendon‐to‐bone injuries after rotator cuff tears	32
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The mitochondrial‐endoplasmic reticulum co‐transfer in dental pulp stromal cell promotes pulp injury repair	31
Corrigendum	31
Single‐cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion	31
LRH‐1 activation alleviates diabetes‐induced podocyte injury by promoting GLS2‐mediated glutaminolysis	31
Mass cytometry and transcriptomic profiling reveal body‐wide pathology induced by Loxl1 deficiency	31
Potential roles of enteric glial cells in Crohn's disease: A critical review	30
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Stroke‐Homing Peptide‐DNase1 Alleviates Intestinal Ischemia Reperfusion Injury by Selectively Degrading Neutrophil Extracellular Traps	29
Accelerating Bone Healing With METTL3 Overexpressed Adipose‐Derived Stem Cells in Osteoporotic Rats	29
Single‐cell RNA sequencing: Inhibited Notch2 signalling underlying the increased lens fibre cells differentiation in high myopia	29
Issue Information	28
G3BP1 coordinates lysophagy activity to protect against compression‐induced cell ferroptosis during intervertebral disc degeneration	28
Opposite roles of Kindlin orthologs in cell survival and proliferation	27
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Post‐hospitalization rehabilitation alleviates long‐term immune repertoire alteration in COVID‐19 convalescent patients	27
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The basic route of nuclear‐targeted transport of IGF‐1/IGF‐1R and potential biological functions in intestinal epithelial cells	26
Corrigendum	26
Baffled‐flow culture system enables the mass production of megakaryocytes from human embryonic stem cells by enhancing mitochondrial function	25
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Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging	25
WNT16b promotes the proliferation and self‐renewal of human limbal epithelial stem/progenitor cells via activating the calcium/calcineurin A/NFATC2 pathway	24

Exosomes on the development and progression of renal fibrosis	24
Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells	24
Lin28a forms an RNA‐binding complex with Igf2bp3 to regulate m6A‐modified stress response genes in stress granules of muscle stem cells	24
A chemically defined system supports two distinct types of stem cell from a single blastocyst and their self‐assembly to generate blastoid	24
Single‐cell RNA sequencing reveals new subtypes of lens superficial tissue in humans	24
Developmental switch from morphological replication to compensatory growth for salamander lung regeneration	24
Wnt10b regulates osteogenesis of adipose‐derived stem cells through Wnt/β‐catenin signalling pathway in osteoporosis	23
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Probiotics ameliorate alveolar bone loss by regulating gut microbiota	23
In vivo development and single‐cell transcriptome profiling of human brain organoids	23
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Flavonoid chrysin activates both TrkB and FGFR1 receptors while upregulates their endogenous ligands such as brain derived neurotrophic factor to promote human neurogenesis	22
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The combination of dextran sulphate and polyvinyl alcohol prevents excess aggregation and promotes proliferation of pluripotent stem cells in suspension culture	22
Increased SPON1 promotes pancreatic ductal adenocarcinoma progression by enhancing IL‐6 trans‐signalling	21
CircSMAD3 represses VSMC phenotype switching and neointima formation via promoting hnRNPA1 ubiquitination degradation	21
Tetrahedral Framework Nucleic Acid‐Based Delivery of DJ‐1‐saRNA Prevent Retinal Ischaemia–Reperfusion Injury via Inhibiting Ferroptosis	20
RETRACTION: Legionella Pneumophila Infection Reduces the Mitochondrial Membrane Potential Through Lpg2444‐Inhibited Mitocytosis	20
Rapid and Effective Neuronal Conversion of Human Glioblastoma In Vitro and In Vivo Using Potent Small Molecules	20
BCL2‐associated athanogene 6 exon24 contributes to testosterone synthesis and male fertility in mammals	20
Extraembryonic mesoderm cells derived from human embryonic stem cells rely on Wnt pathway activation	20
Corrigendum	20
m6A promotes planarian regeneration	19
Single‐cell RNA sequencing to explore cancer‐associated fibroblasts heterogeneity: “Single” vision for “heterogeneous” environment	19
Ubiquitin‐specific peptidases: Players in bone metabolism	19
Combination of chemically modified SDF‐1α mRNA and small skin improves wound healing in diabetic rats with full‐thickness skin defects	19
Conditional Overexpression of Net1 Enhances the Trans‐Differentiation of Lgr5+ Progenitors into Hair Cells in the Neonatal Mouse Cochlea	19
Osteocyte ferroptosis induced by ATF3/TFR1 contributes to cortical bone loss during ageing	19
RNF20 affects porcine adipocyte differentiation via regulation of mitotic clonal expansion	19
Supplementation of mitochondria from endometrial mesenchymal stem cells improves oocyte quality in aged mice	19
The proliferative and multipotent epidermal progenitor cells for human skin reconstruction in vitro and in vivo	19
Oxidative stress in intervertebral disc degeneration: Molecular mechanisms, pathogenesis and treatment	19
Fine‐tuning of dual‐SMAD inhibition to differentiate human pluripotent stem cells into neural crest stem cells	18
Manufacturing with pluripotent stem cells (PSConf 2021): Key issues for future research and development	18
CircNFIX regulates chondrogenesis and cartilage homeostasis by targeting the miR758‐3p/KDM6A axis	18
Comprehensive analysis of human chorionic membrane extracts regulating mesenchymal stem cells during osteogenesis	18
Functional cooperation between IKCa and TRPC1 channels regulates serum‐induced vascular smooth muscle cell proliferation via mediating Ca2+ influx and	17
Issue Information	17
Directed differentiation of human embryonic stem cells into parathyroid cells and establishment of parathyroid organoids	17
Genome‐Wide Screening in Haploid Stem Cells Reveals Synthetic Lethality Targeting MLH1 and TP53 Deficient Tumours	17
Scalable preparation of osteogenic micro‐tissues derived fromhESC‐derived immunity‐and‐matrix‐regulatory cells within porous microcarriers in suspension culture	17
The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases	17
Establishment of human corneal epithelial organoids for ex vivo modelling dry eye disease	17
SETDB1 regulates microtubule dynamics	17
Enhancing targeted transgene knock‐in by donor recruitment	17
Telomere shortening impairs alveolar regeneration	17
Melatonin alleviates vascular endothelial cell damage by regulating an autophagy‐apoptosis axis in Kawasaki disease	17
The Dual Roles of Lamin A/C in Macrophage Mechanotransduction	16
Histone H2B ubiquitination mediated chromatin relaxation is essential for the induction of somatic cell reprogramming	16
Adult spinal cord tissue transplantation combined with local tacrolimus sustained‐release collagen hydrogel promotes complete spinal cord injury repair	16
AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR‐ULK1‐autophagy axis	16
Dnmt1 is required for the development of auditory organs via cell cycle arrest and Fgf signalling	16
Super‐Enhancer Target Gene CBP/p300‐Interacting Transactivator With Glu/Asp‐Rich C‐Terminal Domain, 2 Cooperates With Transcription Factor Forkhead Box J3 to Inhibit Pulmonary Va	16
GFI1 regulates chromatin state essential in human endothelial‐to‐haematopoietic transition	16
Optimizing in vitro T cell differentiation by using induced pluripotent stem cells with GFP‐RUNX1 and mCherry‐TCF7 labelling	16
Progression of irradiated mesenchymal stromal cells from early to late senescence: Changes in SASP composition and anti‐tumour properties	16
Manufacturing clinical‐grade human induced pluripotent stem cell‐derived beta cells for diabetes treatment	16
Decellularised spinal cord matrix manipulates glial niche into repairing phase via serglycin‐mediated signalling pathway	16
HDAC3 in action: Expanding roles in inflammation and inflammatory diseases	16
Ex vivo factor VIII‐modified proliferating human hepatocytes therapy for haemophilia A	16
Circ‐CTNNB1 drives aerobic glycolysis and osteosarcoma progression via m6A modification through interacting with RBM15	16
Issue Information	16
LincRNA‐EPS inhibits caspase‐11 and NLRP3 inflammasomes in gingival fibroblasts to alleviate periodontal inflammation	15
NRF1 promotes primordial germ cell development, proliferation and survival	15
An allied reprogramming, selection, expansion and differentiation platform for creating hiPSC on microcarriers	15
3D printed PCLA scaffold with nano‐hydroxyapatite coating doped green tea EGCG promotes bone growth and inhibits multidrug‐resistant bacteria colonization	15
Splicing control by PHF5A is crucial for melanoma cell survival	15
Thymopentin alleviates premature ovarian failure in mice by activating YY2/Lin28A and inhibiting the expression of let‐7 family microRNAs	15
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Correction to “Functional extracellular matrix hydrogel modified with MSC‐derived small extracellular vesicles for chronic wound healing”	15
Selective utilization of non‐homologous end‐joining and homologous recombination for DNA repair during meiotic maturation in mouse oocytes	15
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Exercise Delays Brain Ageing Through Muscle‐Brain Crosstalk	14
Transcriptome profiles and chromatin states in mouse androgenetic haploid embryonic stem cells	14
Nutrient metabolism in regulating intestinal stem cell homeostasis	14
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Heterogeneous stiffness of the bone marrow microenvironment regulates the fate decision of haematopoietic stem and progenitor cells	14
An RNA methylation code to regulate protein translation and cell fate	14

Issue Information	14
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Premeiotic deletion of Eif2s2 causes oocyte arrest at the early diplotene stage and apoptosis in mice	14
Corrigendum	14
Knowledge graphs of ethical concerns of cerebral organoids	13
Cisplatin‐induced oxPAPC release enhances MDSCs infiltration into LL2 tumour tissues through MCP‐1/CCL2 and LTB4/LTB4R pathways	13
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A DNA nanostructure‐Hif‐1α inducer complex as novel nanotherapy against cisplatin‐induced acute kidney injury	13
AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre‐eclampsia	13
GPD1L‐Mediated Glycerophospholipid Metabolism Dysfunction in Women With Diminished Ovarian Reserve: Insights From Pseudotargeted Metabolomic Analysis of Follicular Fluid	13
RNA‐binding protein ELAVL2 plays post‐transcriptional roles in the regulation of spermatogonia proliferation and apoptosis	13
Abnormal microglial polarization induced by Arid1a deletion leads to neuronal differentiation deficits	13
Single‐cell RNA sequencing in osteoarthritis	13
Urolithin B suppressed osteoclast activation and reduced bone loss of osteoporosis via inhibiting ERK/NF‐κB pathway	13
Immune repertoire analysis of normal Chinese donors at different ages	13
Effects of astragaloside IV on glucocorticoid‐induced avascular necrosis of the femoral head via regulating Akt‐related pathways	13
GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/β‐catenin and ALK5/SMAD2/3 pathways	13
Eukaryotic translation initiation factor eIF4G2 opens novel paths for protein synthesis in development, apoptosis and cell differentiation	13
Establishment and characterization of adult human gastric epithelial progenitor‐like cell lines	13
Colony‐stimulating factor 1 positive (CSF1+) secretory epithelial cells induce excessive trophoblast invasion in tubal pregnancy rupture	12
Generation of stable integration‐free pig induced pluripotent stem cells under chemically defined culture condition	12
Scalable manufacturing of clinical‐grade differentiated cardiomyocytes derived from human‐induced pluripotent stem cells for regenerative therapy	12
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The intact parasympathetic nerve promotes submandibular gland regeneration through ductal cell proliferation	12
Interfering with CSE1L/CAS inhibits tumour growth via C3 in triple‐negative breast cancer	12
Partial depletion and repopulation of microglia have different effects in the acute MPTP mouse model of Parkinson’s disease	12
Role of CXCR4 in the progression and therapy of acute leukaemia	12
Correction to ‘BMAL1 deficiency promotes skeletal mandibular hypoplasia via OPG downregulation’	12
T‐cell infiltration, contribution and regulation in the central nervous system post‐traumatic injury	12
Requirements for human cardiomyocytes	12
Sprouty1 exerts a preventive effect on the initiation of psoriasis by inhibiting innate immune antimicrobial peptide cathelicidin and immunocytes	12
Histatin 1 enhanced the speed and quality of wound healing through regulating the behaviour of fibroblast	12
The role of Trithorax family regulating osteogenic and Chondrogenic differentiation in mesenchymal stem cells	12
Cystathionine β‐synthase is required for oocyte quality by ensuring proper meiotic spindle assembly	12
Sirt3 Rescues Porphyromonas gingivalis‐Impaired Cementogenesis via SOD2 Deacetylation	12
Cholestyramine alleviates bone and muscle loss in irritable bowel syndrome via regulating bile acid metabolism	12
Organoid Models to Study Human Infectious Diseases	12
Non‐SMC condensin I complex subunit H participates in anti‐programmed cell death‐1 resistance of clear cell renal cell carcinomas	12
PFKFB4 facilitates palbociclib resistance in oestrogen receptor‐positive breast cancer by enhancing stemness	12
A regulatory loop of JAK/STAT signalling and its downstream targets represses cell fate conversion and maintains male germline stem cell niche homeostasis	12
YTHDC1 positively regulates PTEN expression and plays a critical role in cisplatin resistance of bladder cancer	11
IKK/NF‐κB and ROS signal axes are involved in Tenacissoside H mediated inhibitory effects on LPS‐induced inflammatory osteolysis	11
MET overexpression in ovarian cancer via CD24‐induced downregulation of miR‐181a: A signalling for cellular quiescence‐like state and chemoresistance in ovarian C	11
Requirements for human‐induced pluripotent stem cells	11
The role of Espin in the stereocilia regeneration and protection in Atoh1‐overexpressed cochlear epithelium	11
Transplantation of tauroursodeoxycholic acid–inducing M2‐phenotype macrophages promotes an anti‐neuroinflammatory effect and functional recovery after spinal cord injury in rats	11
PTH‐induced EndMT via miR‐29a‐5p/GSAP/Notch1 pathway contributed to valvular calcification in rats with CKD	11
Adverse PFAS effects on mouse oocyte in vitro maturation are associated with carbon‐chain length and inclusion of a sulfonate group	11
Single‐cell RNA sequencing gene signatures for classifying and scoring exhausted CD8+ T cells in B‐cell acute lymphoblastic leukaemia	10
Mitonuclear Communication in Stem Cell Function	10
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HN1 Functions in Protein Synthesis Regulation via mTOR‐RPS6 Axis and Maintains Nucleolar Integrity	10
eIF3a‐PPP2R5A‐mediated ATM/ATR dephosphorylation is essential for irinotecan‐induced DNA damage response	10
Investigating Aging‐Related Endometrial Dysfunction Using Endometrial Organoids	10
Bone marrow macrophage‐derived exosomal miR‐143‐5p contributes to insulin resistance in hepatocytes by repressing MKP5	10
Protective roles of cytoplasmic p21Cip1/Waf1 in senolysis and ferroptosis of lung cancer cells	10
Single‐Cell Multiomics Reveals TCR Clonotype‐Specific Phenotype and Stemness Heterogeneity of T‐ALL Cells	10
Single‐Cell Transcriptomics Uncovers Core Signature for Regulating Mitochondrial Homeostasis During Testicular Ageing	10
Optineurin Cooperates With NRF2 to Regulate Tooth Root Morphogenesis by Controlling Mitochondrial Dynamics and Apoptosis	10
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Exploring the Single‐Cell Dynamics of FOXM1 Under Cell Cycle Perturbations	10
Utilising Human Myometrial and Uterine Fibroid Stem Cell‐Derived Three Dimentional Organoids as a Robust Model System for Understanding the Pathophysiology of Uterine Fibroids	9
Suppression of SLC39A6‐CREB1 axis in liver cancer causes PCK1‐mediated mitochondrial dysfunction	9
RETRACTION: MATN1‐AS1 promotes glioma progression by functioning as ceRNA of miR‐200b/c/429 to regulate CHD1 expression	9
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In vitro construction of liver organoids with biomimetic lobule structure by a multicellular 3D bioprinting strategy	9
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Perfect duet: Dual recombinases improve genetic resolution	9
Lactate‐induced protein lactylation: A bridge between epigenetics and metabolic reprogramming in cancer	9
Memory inflation: Beyond the acute phase of viral infection	9
NAT10‐mediated ac4C modification promotes ectoderm differentiation of human embryonic stem cells via acetylating NR2F1 mRNA	9
RETRACTION: Six2 Promotes Non–Small Cell Lung Cancer Cell Stemness Via Transcriptionally and Epigenetically Regulating E‐Cadherin	9
Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone‐derived IGF‐1 secretion	9
Metabolomics analyses reveal the crucial role of ERK in regulating metabolic pathways associated with the proliferation of human cutaneous T‐cell lymphoma cells treated with Glabridin	9
Tetrahedral Framework Nucleic Acid Relieves Sepsis‐Induced Intestinal Injury by Regulating M2 Macrophages	9
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Comparison of seven CD19 CAR designs in engineering NK cells for enhancing anti‐tumour activity	9
SESN1 is a FOXO3 effector that counteracts human skeletal muscle ageing	9
ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression	9
Reduced M2 macrophages and adventitia collagen dampen the structural integrity of blood blister–like aneurysms and induce preoperative rerupture	9
Advances in single‐cell sequencing and its application to musculoskeletal system research	9
Fate tracking reveals differences between Reelin+ hepatic stellate cells (HSCs) and Desmin+HSCs in activation, migration and proliferation	9
Mitochondrial dysfunction is associated with hypertrophic cardiomyopathy in Pompe disease‐specific induced pluripotent stem cell‐derived cardiomyocytes	9
Intermittent hyperglycaemia induces macrophage dysfunction by extracellular regulated protein kinase‐dependent PKM2 translocation in periodontitis	9
New Anti‐Fibrotic Strategies for Keloids: Insights From Single‐Cell Multi‐Omics	9
Intra‐amniotic mesenchymal stem cell therapy improves the amniotic fluid microenvironment in rat spina bifida aperta fetuses	9