Human & Experimental Toxicology

Papers
(The median citation count of Human & Experimental Toxicology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Silver nanoparticles trigger delayed inflammatory responses in mast cells67
Sevoflurane preconditioning attenuates myocardial cell damage caused by hypoxia and reoxygenation via regulating the NORAD/miR-144-3p axis46
Silencing lncRNA HCG18 regulates GPX4-inhibited ferroptosis by adsorbing miR-450b-5p to avert sorafenib resistance in hepatocellular carcinoma43
LINC00641 impeded the malignant biological behaviors of papillary thyroid carcinoma cells via interacting with IGF2BP1 to reduce GLI1 mRNA stability34
Prenatal and early life lead exposure induced neurotoxicity30
LINC00294/miR-620/MKRN2 axis provides biomarkers and negatively regulates malignant progression in colorectal carcinoma29
Oxidative stress reactions in rats with pulmonary injuries induced by sulfur mustard (1 LD 50 )28
Exploring the utility of zinc finger protein-related genes in predicting hepatocellular carcinoma prognosis, immune responses, and drug efficacy26
Human health risk assessment of heavy metals in different compartments of vegetables from Erbil City-Iraq22
Retraction Notice: “Sulforaphane triggers iron overload-mediated ferroptosis in gastric carcinoma cells by activating the PI3K/IRP2/DMT1 pathway”21
Effects of doxorubicin on autophagy in fibroblasts20
Development and validation of a novel poisoning agitation-sedation score for predicting the need for endotracheal intubation and mechanical ventilation in acutely poisoned patients with disturbed cons20
Acriflavine protects against LPS-induced sepsis via regulation of pyroptosis, inflammation, and endoplasmic reticulum stress19
A new 1,4-dihydropyridine-based L-/T-type calcium channel inhibitor, provides in- vivo and silico cardioprotective effects in doxorubicin toxicity in rat19
Hyperoside exerts protective effects against anticardiolipin antibody-induced recurrent pregnancy loss in vivo and in vitro19
Retraction Notice19
Effects of methylphenidate on femoral bone growth in male rats18
Effects of polycyclic aromatic hydrocarbon exposure on mitochondrial DNA copy number18
Neurodevelopmental toxicity induced by PM2.5 Exposure and its possible role in Neurodegenerative and mental disorders18
Clinical characteristics and the risk factors analysis in patients with delayed encephalopathy after acute carbon monoxide poisoning17
Relationship between clock gene expression and CYP2C19 and CYP3A4 with benzodiazepines17
Salidroside attenuates LPS-induced kidney injury through activation of SIRT1/Nrf2 pathway17
Exosomes derived from M2 macrophages promote fibroblast autophagy to contribute to hypertrophic scar formation via CXCL2/CXCR7/mTOR pathway16
RETRACTED: Ginsenoside Rg5 induces NSCLC cell apoptosis and autophagy through PI3K/Akt/mTOR signaling pathway16
The possible cytotoxicity and genotoxicity assessment of indaziflam on HepG2 cells15
RETRACTED: Baicalein exerts beneficial effects in lipopolysaccharide-induced pulmonary inflammation by modulating macrophage polarization and inhibiting pyroptosis15
Retraction notice: “3,4-Methylenedioxymethamphetamine causes retinal damage in C57BL/6J mice”14
Activation of SIRT3/AMPK/mTOR-mediated autophagy promotes quercetin-induced ferroptosis in oral squamous cell carcinoma14
Protective effects of butylated hydroxytoluene on the initiation of N-nitrosodiethylamine-induced hepatocellular carcinoma in albino rats12
RETRACTED: Retrospective analysis of the etiology and drugs for vitreous hemorrhage caused by non-diabetic retinopathy and non-traumatic factors12
TLR4/ MyD88/NF-κB signaling pathway involved in the protective effect of diacerein against lung fibrosis in rats12
RETRACTED: CircRNA_001373 promotes liver fibrosis by regulating autophagy activation in hepatic stellate cells via the miR-142a-5p/Becn1 axis12
Anlotinib induces apoptosis and second growth/mitosis phase block in cisplatin-resistant ovarian cancer cells via the aurora kinase A/p53 pathway11
Stevioside inhibits colorectal cancer progression by regulating macrophage polarization11
Cysteine-rich 61(CYR61) alleviates cyclophosphamide-induced proliferation inhibition in ovarian granulosa cells via suppressing NLRP3/caspase1-mediated p11
The effect of melatonin on capecitabine-induced hepatic and renal toxicity in rats11
MiR-3612 targeting THBS1 suppresses nasopharyngeal carcinoma progression by PI3K/AKT signaling pathway11
RETRACTED: Carvedilol alleviates the detrimental effects of azathioprine on hepatic tissues in experimental rats: Focusing on redox system, inflammatory and apoptosis pathways11
MAPK-interacting kinases inhibition by eFT508 overcomes chemoresistance in preclinical model of osteosarcoma10
Retraction Notice: Association of miR-9-5p and NFIC in the progression of gastric cancer10
A review of challenges and prospects of 3D cell-based culture models used for studying drug induced liver injury during early phases of drug development10
Neuroinflammatory chemokine networks in transgenic models of Alzheimer’s disease: A comparative multi-compartmental analysis10
Cigarette smoking extract induces mitochondrial dysfunction and apoptosis in HUVECs via the Sirt1-SHH axis9
Trimethylamine-N oxide enhances post-stroke depression progression via ROS-p38/MAPK signaling9
Diagnostic and prognostic value of diquat plasma concentration and complete blood count in patients with acute diquat poisoning based on random forest algorithms9
Assessment of safety through mutagenicity and subchronic toxicity studies with black pepper extract preparation9
Anti-oxidative properties of nanocrocin in Zearalenone induced toxicity on Hek293 cell; The novel formulation and cellular assessment9
Environmental contaminants, endocrine disruption, and transgender: Can “born that way” in some cases be toxicologically real?8
RETRACTED: Downregulation of miR-138-5p alleviates propofol-induced neurotoxicity and autophagy by regulating SIRT18
Retraction notice: “Long noncoding RNA SNHG14 regulates ox-LDL-induced atherosclerosis cell proliferation and apoptosis by targeting miR-186-5p/WIPF2 axis”8
Persistent diazinon induced neurotoxicity: The effect on inhibitory avoidance memory performance, amyloid precursor proteins, and TNF-α levels in the prefrontal cortex of rats8
Correction to “Corrigendum to effect of grape seed extract ondoxorubicin-induced testicular andepididymal damage in rats”8
Evaluation of the effectiveness of fresh frozen plasma transfusion as adjuvant treatment in acute organophosphate-poisoned patients: A randomized clinical trial8
Emodin protects against apoptosis and inflammation by regulating reactive oxygen species-mediated NF- κ B signaling in interleukin‐1 7
Increased FGFR3 is involved in T-2 toxin-induced lesions of hypertrophic cartilage associated with endemic osteoarthritis7
SEMA3C regulates tumor-associated macrophage phenotype and influences lung cancer cell migration and invasion through VNN17
Protective effects of brain and muscle ARNT-like gene 1 on oxidized low-density lipoprotein-induced human brain microvascular endothelial cell injury by alleviating ferroptosis7
Establishment of a rat model of bronchopulmonary dysplasia complicated with pulmonary hypertension and its potential applications7
Anti-EMT properties of ergothioneine attenuate lipopolysaccharide-induced oxidative stress-mediated acute lung injury via modulating TGF-β/smad/snail signaling pathway7
Tricin attenuates diabetic retinopathy by inhibiting oxidative stress and angiogenesis through regulating Sestrin2/Nrf2 signaling7
Clinical utility of combined butyrylcholinesterase activity measurements in assessing acute malathion intoxication severity: A case series7
Subchronic inhalation of a novel electronic nicotine delivery system formulation and its corresponding base formulation6
Omarigliptin/shikonin combination alleviates cyclosporine-induced nephrotoxicity: The role of sirtuin 1, glucagon-like peptide-1, HMGB1/RAGE/TLR4 signaling, and p38/ERK/JNK MAPKs6
RETRACTED: Sulforaphane triggers iron overload-mediated ferroptosis in gastric carcinoma cells by activating the PI3K/IRP2/DMT1 pathway6
Alleviation of the mitochondrial dynamics impairment in doxorubicin-induced cardiomyocyte toxicity by cardioprotective agents6
“YTHDF1-mediated sphingosine kinase 2 upregulation alleviates bupivacaine-induced neurotoxicity via the PI3K/AKT axis”6
CircKRT14 upregulates E2F3 by interacting with miR-1256 to act as an oncogenic factor in esophageal cancer6
RETRACTED: Ginsenoside Re suppresses high glucose-induced apoptosis of placental trophoblasts through endoplasmic reticulum stress-related CHOP/GADD1536
Retraction Notice6
Down-regulation of E2F1 attenuates UVB-induced human lens epithelial cell oxidative stress and pyroptosis through inhibiting NLRP36
Renal glucose transporters play a role in removal of cadmium from kidney cells mediated by GMDTC – A novel metal chelator6
Retraction: Protection by pentoxifylline of malathion-induced toxic stress and mitochondrial damage in rat brain6
Nickel; a metal with threats to human health, focusing on its intoxication mechanisms6
Establishment of an animal model of sciatic nerve injury induced by local anesthetics6
Nomogram for predicting mechanical ventilation need among acutely intoxicated patients with impaired consciousness: Correspondence6
Hypoxia-induced autophagy attenuates ferredoxin 1-mediated cuproptosis in colorectal cancer cells6
Retraction Notice6
Discovering the most impactful treatments for aluminum phosphide cardiotoxicity gleaned from systematic review of animal studies6
Cathepsin B mediates the lysosomal-mitochondrial apoptosis pathway in arsenic-induced microglial cell injury6
Neurologic disease produced by Rathayibacter toxicus -derived corynetoxins6
Ozone in the adjunct medical treatment. The round personality of a molecule with hormetic properties5
High-dose vitamin C potently induces apoptosis in acute lymphoblastic leukemia by activating ER stress response5
Corrigendum to “Diagnostic and prognostic value of diquat plasma concentration and complete blood count in patients with acute diquat poisoning based on random forest algorithms”5
RNA-seq analysis revealed genes associated with neuropathic pain induced by chronic compressive injury in interferon regulatory factors 4 knockout mice5
Water-soluble Yb 3+ , Er 3+ codoped NaYF 4 nano5
Alkylating agents are possible inducers of glioblastoma and other brain tumors5
Corrigendum to “Apoptosis-promoting and migration-suppressing effect of alantolactone on gastric cancer cell lines BGC-823 and SGC-7901 via regulating p38MAPK and NF-κB pathways”5
Evaluation of Cd-induced cytotoxicity in primary human keratinocytes5
Targeted inhibition of STING-TBK1 axis alleviates the hepatotoxicity of tripterygium glycosides5
Retraction Notice5
Rhamnazin ameliorates 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-evoked testicular toxicity by restoring biochemical, spermatogenic and histological profile in male albino rats5
Circ_0000285 regulates nasopharyngeal carcinoma progression through miR-1278/FNDC3B axis4
KLF9 mediates NLRP3 inflammasome and reactive oxygen species to mediate pyroptosis in trophoblasts4
Clinical and laboratory prognostic factors associated with methanol toxicity outcomes in patients at Tabriz Sina Hospital: A retrospective study4
Dexmedetomidine and propofol-induced neurotoxicity: Promise, but caution warranted4
Potential induction of h yperkeratosis in r ats’ c ervi 4
Effect of grape seed extract on doxorubicin-induced testicular and epididymal damage in rats4
Punicalagin is cytotoxic to human colon cancer cells by modulating cell proliferation, apoptosis, and invasion4
Curculigoside attenuates cerebral ischemia-reperfusion injury via TRPM2-mediated microglial polarization4
Integrated gut microbiota and serum metabolomics reveal glyphosate-induced hepatic injury in mice4
Stereotactic body radiation therapy suppresses myeloid-derived suppressor cells by regulating miR-21/Sorbin and SH3 Domain-containing Protein 1 axis4
Hepatoprotective potential of diosmin against hepatotoxic effect of isoniazid and rifampin in wistar rats4
MG132 inhibits proliferation and induces apoptosis of acute lymphoblastic leukemia via Akt/FOXO3a/Bim pathway4
Retraction: Ginsenoside re suppresses high glucose-induced apoptosis of placental trophoblasts through endoplasmic reticulum stress-related CHOP/GADD1534
Ergot alkaloid consumption alters serotonin receptor-induced vasoactivity in ovine umbilical vasculature4
Comparing the effectiveness of L-carnitine and paraffin oil in acute aluminum phosphide poisoning using predictive biomarkers and scores: A randomized controlled clinical trial4
Acrylamide-induced meiotic arrest of spermatocytes in adolescent mice by triggering excessive DNA strand breaks: Potential therapeutic effects of resveratrol4
Follow-up of patients with a 5-year survival after paraquat poisoning using computed tomography images and spirometry4
RETRACTED: Arsenic-induced downregulation of BRWD3 suppresses proliferation and induces apoptosis in lung adenocarcinoma cells through the p53 and p65 pathways4
The effects of esketamine on the intestinal microenvironment and intestinal microbiota in mice4
RETRACTED: Comparative analysis of noise and music exposure on inflammatory responses on lipopolysaccharide-induced septic rats4
Mechanism of triiodothyronine alleviating acute alcoholic liver injury and delaying alcoholic liver fibrosis progression4
Development and validation of a nomogram for predicting mechanical ventilation need among acutely intoxicated patients with impaired consciousness4
Pelargonidin-3-O-glucoside prevents isoproterenol-induced myocardial infarction via modulating cardiac and inflammatory markers expression in experimental rats4
Ginkgolide A downregulates transient receptor potential (melastatin) 2 to protect cisplatin-induced acute kidney injury in rats through the TWEAK/Fn14 pathway: Ginkgolide A improve acute renal injury4
Conflicts of interest in the International Agency for Research on Cancer process of identifying carcinogenic hazards to humans3
Retraction Notice3
Association between serum complement 1q and the associated factors of acute ischemic stroke in patients with type 2 diabetes3
In silico evaluations of phytochemicals from Withania somnifera exhibiting anticancer activity against NAD[P]H-quinone oxidore3
Physalin A induces apoptosis through conjugating with Fas-FADD cell death receptor in human oral squamous carcinoma cells and suppresses HSC-3 cell xenograft tumors in NOD/SCID mice3
Withdrawn—Administrative Error: “Corrigendum to ‘Carvedilol alleviates the detrimental effects of azathioprine on hepatic tissues in experimental rats: Focusing on redox system, inflammatory and apopt3
Microsomal glutathione S-transferase 1 targets the autophagy signaling pathway to suppress ferroptosis in gastric carcinoma cells3
An artificial intelligence algorithm for analyzing globus pallidus necrosis after carbon monoxide intoxication3
Liver and ovarian toxicities boosted by bisphenol and gamma radiation in female albino rats3
Histological and immunohistochemical alterations in the brain tissues induced by the subchronic toxicity of gold nanoparticles: In vivo study3
Preclinical Evaluation of interferon-gamma primed human Wharton’s jelly-derived mesenchymal stem cells3
Insights into therapeutic potential and practical applications of natural toxins from poisonous mushrooms3
Problems with the effectiveness of L-carnitine and paraffin oil in acute aluminum phosphide poisoning3
The acute and sub-chronic toxicological effects of 3-amino-9-ethylcarbazole (AEC) on zebrafish3
Wasp-stung rat model translationally expresses the coagulopathy manifestations of human wasp patients3
Integrative analysis of renal microRNA and mRNA to identify hub genes and pivotal pathways associated with cyclosporine-induced acute kidney injury in mice3
Retraction: Protective effects of casein-derived peptide VLPVPQK against hydrogen peroxide-induced dysfunction and cellular oxidative damage in rat osteoblastic cells3
Nrf2 attenuates methamphetamine-induced myocardial injury by regulating oxidative stress and apoptosis in mice3
Effects of combined exposure of manganese and iron on serum inflammatory factor levels among workers3
Impact of combined chronic exposure to low-dose bisphenol A and fructose on serum adipocytokines and the energy target metabolome in white adipose tissue3
Protocatechuic acid mitigates 5-fluorouracil-triggered renal and hepatic injury in rats3
Retraction Notice3
0.087870836257935