Anti-Cancer Drugs

Article	Citations
Effect of berbamine on invasion and metastasis of human liver cancer SMMC-7721 cells and its possible mechanism	55
FV-429 suppresses cancer cell migration and invasion by EMT via the Hippo/YAP1 pathway in pancreatic cancer cells	51
eIF4E-eIF4G complex inhibition synergistically enhances the effect of sorafenib in hepatocellular carcinoma	24
Hypoxia-inducible factor-1α inhibition augments efficacy of programmed cell death 1 antibody in murine prostatic cancer models	21
BTK inhibitors enhance NKG2D ligand expression by regulating IL-10/STAT3 pathway in activated non-GCB diffuse large B-cell lymphoma cells	20
A retrospective assessment of real-world experience with venetoclax and azacitidine therapy in elderly acute myeloid leukemia	19
Rapid and durable response to fifth-line lorlatinib plus olaparib in an ALK-rearranged, BRCA2-mutated metastatic lung adenocarcinoma patient with critical tracheal stenosis: a case report	19
Knockdown of circLRWD1 weakens DDP resistance via reduction of SIRT5 expression through releasing miR-507 in non-small cell lung cancer	18
YKL-06-061 exerts antitumor effect through G1/S phase arrest by downregulating c-Myc and inhibition of metastasis via SIK1 upregulation in pancreatic cancer	18
Pyrotinib treatment enhances the radiosensitivity in HER2-positive brain metastatic breast cancer patients	18
Circ_0003998 upregulates ARK5 expression to elevate 5-Fluorouracil resistance in hepatocellular carcinoma through binding to miR-513a-5p	18
Neutrophil-to-lymphocyte ratio predicts therapy outcomes of transarterial chemoembolization combined with tyrosine kinase inhibitors plus programmed cell death ligand 1 antibody for unresectable hepat	18
Acquired EML4-ALK fusion and EGFR C797S in cis mutation as resistance mechanisms to osimertinib in a non-small cell lung cancer patient with EGFR L858R/T790M	17
WISP1 inhibition of YAP phosphorylation drives breast cancer growth and chemoresistance via TEAD4 activation	16
Circular RNA circ_0073181 contributes to tumorigenesis by regulating protein tyrosine phosphatase receptor type E via miR-548p in hepatocellular carcinoma	16
Nivolumab combined docetaxel versus nivolumab in patients with previously treated nonsmall cell lung cancer: a phase 2 study	16
Long noncoding RNA ZFPM2-AS1 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by regulating the miR-576-3p/HIF-1α axis	15
Interferon-α1b for the treatment of metastatic melanoma: results of a retrospective study	15
Complete response of recurrent perihilar cholangiocarcinoma following sintilimab combined with lenvatinib plus S-1: a case report and review of literature	14
Aumolertinib-based comprehensive treatment for an uncommon site of EGFR exon 20 insertion mutations with multiple metastases non-small cell lung cancer: a case report	14
Partial response of metastatic cardia neuroendocrine carcinoma with the combined therapy involving PD-1 blockade after failed multi-line chemotherapies: a case report and literature review	14
CircRNA B cell linker regulates cisplatin sensitivity in nonsmall cell lung cancer via microRNA-25-3p/BarH‑like homeobox 2 axis	14
Downregulation of RPS14 inhibits the proliferation and metastasis of estrogen receptor-positive breast cancer cells	13
Circ_0005615 contributes to the progression and Bortezomib resistance of multiple myeloma by sponging miR-185-5p and upregulating IRF4	13
The prolonged clinical benefit with metronomic chemotherapy (VEX regimen) in metastatic breast cancer patients	13

LncRNA FOXP4-AS1 silencing inhibits metastasis and epithelial–mesenchymal transition in nasopharyngeal carcinoma via miR-136-5p/MAPK1	13
Computational study of novel natural inhibitors targeting Kirsten rat sarcoma viral oncogene homolog G12C	13
Interference with PLA2G16 promotes cell cycle arrest and apoptosis and inhibits the reprogramming of glucose metabolism in multiple myeloma cells by modulating the Hippo/YAP signaling pathway	13
Repurposing calcium channel blockers: may be sensible combination with erlotinib for non-small cell lung cancer	12
Remarkable response to gemcitabine rechallenge in advanced urothelial carcinoma: a case report	12
Transcription factor ZEB1 regulates PLK1-mediated SKA3 phosphorylation to promote lung cancer cell proliferation, migration and cell cycle	12
Anoikis-related lncRNA signature predicts prognosis and is associated with immune infiltration in hepatocellular carcinoma	12
HER2-positive advanced biliary tract cancer responds to second-line pyrotinib therapy: a case report	11
Identification of exosomal circRNA CD226 as a potent driver of nonsmall cell lung cancer through miR-1224-3p/high mobility group AT-hook 2 axis	11
M2 tumor-associated macrophage promoted DNA methylation in lung cancer metastasis via intensifying EZH2	11
TRIM11 expression levels was downregulated and prevents ferroptosis of cardiomyocyte by Dusp6 in acute myocardial infarction	11
Circular RNA circ_0000592 elevates ANXA4 expression via sponging miR-1179 to facilitate tumor progression in gastric cancer	11
Afatinib in the treatment of brain metastases of lung cancer with one rare EGFR mutation: a two-case report	11
APLNR promotes the progression of osteosarcoma by stimulating cell proliferation and invasion: Retraction	11
Real-world efficacy and safety of lorlatinib in treating advanced ALK-positive non–small cell lung cancer patients	11
Venetoclax-induced vitiligo in a patient with chronic lymphocytic leukemia	11
Bevacizumab and anexelekto inhibitor, TP-0903 inhibits TGF-β1-induced epithelial–mesenchymal transition of colon cancer cells	11
Anticancer properties of novel zinc oxide quantum dot nanoparticles against breast cancer stem-like cells	10
Anlotinib is effective in the treatment of advanced pancreatic cancer: a case report	10
Impact of KMN network genes on progression and prognosis of non-small cell lung cancer	10
Real-life data on adjuvant trastuzumab emtansine treatment in early-stage HER2-positive breast cancer: a Turkish Oncology Group study	10
ZNF668: a new diagnostic predictor of kidney renal clear cell carcinoma	10
Epidermal growth factor receptor mutation p.A864V in small cell lung cancer and lung squamous cell carcinoma: a case report and review of literature	10
Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report	10
Osimertinib is an effective epidermal growth factor receptor-tyrosine kinase inhibitor choice for lung cancer with epidermal growth factor receptor exon 18–25 kinase domain duplication: report of two	10
Pazopanib-induced chylothorax in a patient with renal cell carcinoma	10
MiR-30a-5p/CHD1 axis enhances cisplatin sensitivity of ovarian cancer cells via inactivating the Wnt/β-catenin pathway	9
Successful immunotherapy with PD-1 Iinhibitor for advanced pancreatic cancer: report of two cases and review of literature	9
Extended survival in a case of metastatic choroidal melanoma with immunotherapy	9
Identifying predictive biomarkers of apatinib in third-line treatment of advanced colorectal cancer through comprehensive genomic profiling	9
Circ_0009035 regulates the progression of cervical cancer by targeting miR-1305/CREBRF axis	9
Evaluation of nuclear PGAM2 value in hepatocellular carcinoma prognosis	9
Transcriptional regulation of CYR61 and CTGF by LM98: a synthetic YAP-TEAD inhibitor that targets in-vitro vasculogenic mimicry in glioblastoma cells	9
Successful treatment with lenvatinib in a patient with thymic carcinoma presenting with cardiac tamponade: a case report and review of literature	9
CircSETDB1 contributes to paclitaxel resistance of ovarian cancer cells by sponging miR-508-3p and regulating ABCC1 expression	9
DNA methyltransferase inhibitor 5-azacytidine enhances neuroblastoma cell lysis by an oncolytic parainfluenza virus	9
miR-26b-5p suppresses chemoresistance in breast cancer by targeting serglycin	9
Tislelizumab plus chemotherapy is an optimal option for second-line treatment for advanced gastroesophageal junction adenocarcinoma	9
HMOX1 regulates ferroptosis via mic14 and its impact on chemotherapy resistance in small-cell lung cancer	9
Differential functionality of fluoropyrimidine nucleosides for safe cancer therapy	9
Complete response to first-line osimertinib monotherapy in a complex epidermal growth factor receptor mutant (L833V/H835L) lung adenocarcinoma patient: a case report	8
Expression and clinical significance of CXCL17 and GPR35 in endometrial carcinoma	8
Berberine inhibits prostate cancer progression by inducing ferroptosis: evidence from network pharmacology	8
Salvage chemotherapy in patients with nonsmall cell lung cancer after prior immunotherapy: a retrospective, real-life experience study	8
Effect of statins use on risk and prognosis of breast cancer: a meta-analysis	8
Circ_0085495 knockdown reduces adriamycin resistance in breast cancer through miR-873-5p/integrin β1 axis	8
AZD7762 induces CRBN dependent BAG3 degradation through ubiquitin-proteasome pathway	8
Immunotherapy combined with chemotherapy in the treatment for rare primary mucoepidermoid carcinoma of the liver: a case report	8
Rare anti-VEGFR therapy-induced toxicity and long-term response to immunotherapy in a rare non-clear cell renal cell carcinoma patient	8
Circ_0001658 regulates gefitinib resistance of non-small cell lung cancer through miR-409-3p/TWIST1 axis	8

Intravenous immunoglobulin efficacy on pembrolizumab induced severe toxic epidermal necrolysis	8
Reuse of osimertinib after small cell lung cancer transformation in lung adenocarcinoma with de-novo epidermal growth factor receptor T790M mutation: case report	8
Apoptotic and autophagic cell death induced in cervical cancer cells by a dual specific oncolytic adenovirus	8
Ado-trastuzumab emtansine in the treatment of lung adenocarcinoma with ERBB2 mutation: a case report and literature review	8
Biodegradable controlled-release polymer containing butylidenephthalide to treat a recurrent cervical spine glioblastoma with promising result: a compassionate trial report	8
Analysis of clinical factors associated with survival in patients with soft-tissue sarcoma receiving trabectedin	8
Blocking circ_0010235 suppresses acquired paclitaxel resistance of non-small cell lung cancer by sponging miR-512-5p to modulate FAM83F expression	8
Kruppel-like factor 5 enhances proliferation, lipid droplet formation and oxaliplatin resistance in colorectal cancer by promoting fatty acid binding protein 6 transcription	8
M2 macrophage-derived exosomal miR-1911-5p promotes cell migration and invasion in lung adenocarcinoma by down-regulating CELF2-activated ZBTB4 expression	7
Lidocaine hampers colorectal cancer process via circITFG2/miR-1204/SOCS2 axis	7
Clinical and radiological evaluation of a phyllodes tumor of the breast: a case report	7
CDKN2A inhibited ferroptosis through activating JAK2/STAT3 pathway to modulate cisplatin resistance in cervical squamous cell carcinoma	7
Hemodialysis requirement after the first dose of durvalumab following chemoradiation therapy: a case report	7
Mucinous appendiceal adenocarcinoma invading the bladder: not always an easy diagnosis. A case report	7
Pyrotinib for HER2-amplified non-small cell lung cancer patient after progression to Afatinib: a case report	7
Long-term survival of an ALK fusion lung adenocarcinoma patient with high mutation burden and microsatellite instability high: a case report	7
GATA3 positively regulates PAR1 to facilitate in vitro disease progression and decrease cisplatin sensitivity in neuroblastoma via inhibiting the hippo pathway	7
A late relapse thymoma and pure red cell aplasia case with an over 5 years of clinical response under everolimus	7
Potential mechanism of pyrotinib-induced diarrhea was explored by gut microbiome and ileum metabolomics	7
Diagnostic and prognostic value of serum soluble B7-H3 in nonsmall cell lung cancer	7
What management for epidermal growth factor receptor-mutated non–small-cell lung cancer, with squamous cell transformation and T790M-acquired resistance mechanisms? A Case report and review of literat	7
GZ17-6.02 interacts with carboplatin and etoposide to kill neuroblastoma cells	6
DEPDC1 affects autophagy-dependent glycolysis levels in human osteosarcoma cells by modulating RAS/ERK signaling through TTK	6
Aurora kinase inhibitor VX-680 enhances sensitivity of esophageal squamous cell carcinoma cells to cisplatin chemotherapy	6
Dexmedetomidine disrupts esophagus cancer tumorigenesis by modulating circ_0003340/miR-198/HMGA2 axis	6
Pretreatment platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio as a predictor of pathological complete response to neoadjuvant chemotherapy in patients with breast cancer: single center	6
Stewart-Treves syndrome in an older woman successfully treated by metronomic chemotherapy: case report and literature survey	6
Long-chain noncoding ribonucleic acids affect the survival and prognosis of patients with esophageal adenocarcinoma through the autophagy pathway: construction of a prognostic model	6
Pulmonary toxicity following administration of granulocyte colony-stimulating factor during chemotherapy for breast cancer: a case report and literature review	6
CircFOXM1 silencing represses cell proliferation, migration and invasion by regulating miR-515-5p/ADAM10 axis in prostate cancer	6
Exosomal miR-93-5p from cancer-associated fibroblasts confers malignant phenotypes on bladder cancer cells by targeting PAFAH1B1	6
Mechanism of gemcitabine combined with lobaplatin in interventional treatment of locally advanced cervical cancer	6
First case report of sunvozertinib for the treatment of HER2 exon 20 insertion in lung adenocarcinoma	6
Antineoplastic activity of GP-2250 in-vitro and in mouse xenograft models	6
Combating anoikis resistance: bioactive compounds transforming prostate cancer therapy	6
Exosomal circ_0007385 enhances non-small cell lung cancer cell proliferation and stemness via regulating miR-1253/FAM83A axis	6
Response to olaparib in metastatic lung adenocarcinoma with germline BRCA2 mutation: a case report	6
Circ_0027089 regulates NACC1 by targeting miR-136-5p to aggravate the development of hepatitis B virus-related hepatocellular carcinoma	6
A meta-analysis of the effect and safety of platinum-based neoadjuvant chemotherapy in treatment of resectable triple-negative breast cancer	6
Concurrent NRAS-BRAF variants in metastatic colorectal cancer: a Tunisian case report	6
Norcantharidin counteracts acquired everolimus resistance in renal cell carcinoma by dual inhibition of mammalian target of rapamycin complex 1 and complex 2 pathways in Vitro	6
Azacitidine combined with venetoclax alleviates AML-MR with TP53 mutation in SDS: a case report and literature review	6
Hyper-late major response after 5 years of nivolumab: role of treatment beyond progression in head and neck cancer	6
Comparison of effects of tamoxifen and Toremifene on hepatic function and serum lipids in breast cancer patients during adjuvant endocrine therapy	6
A meta-analysis on overall survival and safety outcomes in patients with nonmetastatic castration-resistant prostate cancer treated with novel hormonal agents	6
A dual thermo/pH-sensitive hydrogel as 5-Fluorouracil carrier for breast cancer treatment	6
Exploring the repurposing potential of telmisartan drug in breast cancer: an in-silico and in-vitro approach	6
MiR-302c-5p affects the stemness and cisplatin resistance of nasopharyngeal carcinoma cells by regulating HSP90AA1	6
Efficacy and safety of sintilimab combined with apatinib as third-line or above therapy for patients with advanced or metastatic gastric cancer	6
Immunotherapy rechallenge of advanced lung adenocarcinoma with cadonilimab (PD-1/CTLA-4 Bi-specific antibody): a case report	6
Utidelone plus pembrolizumab as the fourth-line combination treatment in non-small cell lung cancer with EGFR mutation: a case report	6
Combined protein and transcriptomics identifies DCTPP1 as a putative biomarkers for predicting immunotherapy responsiveness in gastric cancer patients	5
Anti-androgen for myoepithelial tumor: a potent therapy yet a potential misleader	5
LMCD1 antisense RNA 1 is a newly identified long noncoding RNA	5
Knockdown of circ-PIP5K1A overcomes resistance to cisplatin in ovarian cancer by miR-942-5p/NFIB axis	5
Successful treatment of severe lung cancer caused by third-generation EGFR-TKI resistance due to EGFR genotype conversion with afatinib plus anlotinib	5
First-line crizotinib therapy is effective for a novel SEC31A-anaplastic lymphoma kinase fusion in a patient with stage IV lung adenocarcinoma: a case report and literature reviews	5
LncRNA PCAT6 activated by SP1 facilitates the progression of breast cancer by the miR-326/LRRC8E axis	5
Stat3 shRNA delivery with folate receptor-modified multi-functionalized graphene oxide particles for combined infrared radiation and gene therapy in hepatocellular carcinoma	5
Therapeutic effects of vitamin D and IL-22 on methotrexate-induced mucositis in mice	5
Pathological complete response achieved with FLOT chemotherapy in two patients with MSI-H esophagogastric junction and gastric adenocarcinoma	5
USP3 promotes cisplatin resistance in non-small cell lung cancer cells by suppressing ACOT7-regulated ferroptosis	5
A review of research progress on mechanisms and overcoming strategies of acquired osimertinib resistance	5
The prognostic values of prognostic nutritional index in extensive-stage small-cell lung cancer	5
Propranolol suppresses infantile hemangioma cell proliferation and promotes apoptosis by upregulating miR-125b expression: Retraction	5
Effect of GADD45G on the radioresistance of nasopharyngeal carcinoma cells	5
Effect of metformin use on the risk and prognosis of colorectal cancer in diabetes mellitus: a meta-analysis	5
Association between SLCO1B1 polymorphism and methotrexate-induced hepatotoxicity: a systematic review and meta-analysis	5
Risk-tailored treatment of splenic marginal zone lymphoma	5
Asynchrony of primary tumor and mediastinal lymph nodes response after neoadjuvant immunotherapy plus chemotherapy in a patient with stage IIIA non–small-cell lung cancer: a case report	5
Metastatic small cell lung cancer – an aggressive disease: a case report and literature review	5
Methyltransferase-like 3 enhances cell proliferation and cisplatin resistance in natural killer/T-cell lymphoma through promoting N6-methyladenosine modification and the stability of staphylococcal nu	5
In regard to Cabezas-Camarero et al.	5
Unexpected response to fourth-line paclitaxel in a patient with metastatic oropharyngeal squamous cell carcinoma, immunotherapy-refractory: a case report	5
Long-term response to immuno-oncology after discontinuation for immuno-related pneumonia in metastatic renal carcinoma: a case report	5
BAP1 loss confers sensitivity to bromodomain and extra-terminal inhibitors in renal cell carcinoma	5
Inhibition of MNK pathway sensitizes nasopharyngeal carcinoma to radiotherapy	5
The role of emodin on cisplatin resistance reversal of lung adenocarcinoma A549/DDP cell	5
Research on the mechanism of eugenol in the treatment of liver cancer based on network pharmacology, molecular docking technology, and in vitro experiments	5
Natural products inducing nucleolar stress: implications in cancer therapy	5

A case of lung adenocarcinoma with MET∆ex14 mutation regressed after preoperative treatment with savolitinib, and successfully underwent radical resection	5
Response to erlotinib and bevacizumab combination therapy after acquired resistance to osimertinib in patients with non-small cell lung cancer	5
Chemoimmunotherapy after progression on single-agent pembrolizumab for metastatic urothelial carcinoma: a case series	5
Long-term extracranial metastatic relapse of an intraventricular solitary fibrous tumor: a case report	5