OOIR: Observatory of International Research

Papers

(The H4-Index of Current Opinion in Structural Biology is 48. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
How molecular modelling can better broaden the understanding of glycosylations	271
HIV-1 gp160 in nanodiscs: Unravelling structures and guiding vaccine design	193
Editorial	156
Harnessing the 14-3-3 protein–protein interaction network	120
Optogenetic enzymes: A deep dive into design and impact	112
Mutational fitness landscape and drug resistance	107
Single-particle Cryo-EM and molecular dynamics simulations: A perfect match	105
Pump-like channelrhodopsins: Not just bridging the gap between ion pumps and ion channels	101
Recent advances in AI-driven pKa prediction for proteins and small molecules	93
Computer-aided drug design, quantum-mechanical methods for biological problems	89
Advancing biomolecular simulation through exascale HPC, AI and quantum computing	87
Structure-based virtual screening of vast chemical space as a starting point for drug discovery	82
Raman spectroscopy and imaging of protein droplet formation and aggregation	82
Genome modeling: From chromatin fibers to genes	81
Catalysis and structure of nitrogenases	79
May the proton motive force be with you: A plant transporter review	79
Next-generation predictors of protein phase behavior	77
Navigating protein–nucleic acid sequence-structure landscapes with deep learning	77
Access and utilization of long chain fatty acyl-CoA by zDHHC protein acyltransferases	76
Single-point mutations in disordered proteins: Linking sequence, ensemble, and function	70
Editorial Board	69
Markov field models: Scaling molecular kinetics approaches to large molecular machines	69
Mutually beneficial confluence of structure-based modeling of protein dynamics and machine learning methods	68
NMR tools to detect protein allostery	66
Editorial overview: Biophysical methods: Exploring structures in motions, from biomolecules to cells, and how to drug them	66

Old and new tactics of CRISPR-centric competition between bacteria and bacteriophages	64
Modeling membranes in situ	64
Advancing protein structure prediction beyond AlphaFold2	63
Advances in native cell membrane nanoparticles system	62
Mucin networks: Dynamic structural assemblies controlling mucus function	61
Dynamics and interactions of intrinsically disordered proteins	61
Molecular dynamics simulations for the study of chromatin biology	60
Deep learning for intrinsically disordered proteins: From improved predictions to deciphering conformational ensembles	60
Protein dynamics underlying allosteric regulation	60
The mannose receptor ligands and the macrophage glycome	59
Proteins with alternative folds reveal blind spots in AlphaFold-based protein structure prediction	56
Conformational penalties: New insights into nucleic acid recognition	56
In situ single-particle Cryo-EM methods: Principle and applications	56
Artificial intelligence in therapeutic antibody design: Advances and future prospects	54
CryoEM of V-ATPases: Assembly, disassembly, and inhibition	54
Therapeutic implications of target residence time	54
NMR of RNA - Structure and interactions	53
Dynamic interactions drive early spliceosome assembly	53
Table of contents	50
Table of contents	50
Macromolecular assemblies: Molecular mechanisms abound	49
Editorial overview: Molecular determinants, mechanisms, and state-of-the-art approaches in allostery	48
Probing protein–DNA interactions and compaction in nanochannels	48
Insight into the structural dynamics of light sensitive proteins from time-resolved crystallography and quantum chemical calculations	48