OOIR: Observatory of International Research

Papers

(The H4-Index of Current Opinion in Structural Biology is 44. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Single-particle Cryo-EM and molecular dynamics simulations: A perfect match	160
Single-point mutations in disordered proteins: Linking sequence, ensemble, and function	135
In silico reconstitution of DNA replication. Lessons from single-molecule imaging and cryo-tomography applied to single-particle cryo-EM	121
How molecular modelling can better broaden the understanding of glycosylations	112
Mutational fitness landscape and drug resistance	111
Editorial	110
Advancing biomolecular simulation through exascale HPC, AI and quantum computing	101
Pump-like channelrhodopsins: Not just bridging the gap between ion pumps and ion channels	100
Computer-aided drug design, quantum-mechanical methods for biological problems	99
Harnessing the 14-3-3 protein–protein interaction network	88
Access and utilization of long chain fatty acyl-CoA by zDHHC protein acyltransferases	85
May the proton motive force be with you: A plant transporter review	80
Structure-based virtual screening of vast chemical space as a starting point for drug discovery	76
Catalysis and structure of nitrogenases	76
Genome modeling: From chromatin fibers to genes	73
Structure-based analyses of gut microbiome-related proteins by neural networks and molecular dynamics simulations	71
Editorial overview: Biophysical methods: Exploring structures in motions, from biomolecules to cells, and how to drug them	68
Mucin networks: Dynamic structural assemblies controlling mucus function	66
NMR tools to detect protein allostery	66
The mannose receptor ligands and the macrophage glycome	65
Structural insights into host–microbe glycointeractions	65
Principles of nucleosome recognition by chromatin factors and enzymes	64
Modeling membranes in situ	64
Gut power: Modulation of human amyloid formation by amyloidogenic proteins in the gastrointestinal tract	63
Conformational penalties: New insights into nucleic acid recognition	60

Editorial Board	59
Advancing protein structure prediction beyond AlphaFold2	59
Quantitative characterization of O-GalNAc glycosylation	59
Inner workings of RAG recombinase and its specialization for adaptive immunity	59
Markov field models: Scaling molecular kinetics approaches to large molecular machines	56
Protein dynamics underlying allosteric regulation	54
Implications of disease-related mutations at protein–protein interfaces	54
Mutually beneficial confluence of structure-based modeling of protein dynamics and machine learning methods	52
Proteins with alternative folds reveal blind spots in AlphaFold-based protein structure prediction	51
Molecular dynamics simulations for the study of chromatin biology	51
Dynamics and interactions of intrinsically disordered proteins	50
Deep learning for intrinsically disordered proteins: From improved predictions to deciphering conformational ensembles	50
Challenges and compromises: Predicting unbound antibody structures with deep learning	48
Interpretable artificial intelligence and exascale molecular dynamics simulations to reveal kinetics: Applications to Alzheimer's disease	48
Structural insights into assembly of transcription preinitiation complex	48
Viral amyloids: New opportunities for antiviral therapeutic strategies	47
Biomolecular simulations at the exascale: From drug design to organelles and beyond	46
Editorial overview: Molecular determinants, mechanisms, and state-of-the-art approaches in allostery	46
CryoEM of V-ATPases: Assembly, disassembly, and inhibition	45
Table of contents	44
Insight into the structural dynamics of light sensitive proteins from time-resolved crystallography and quantum chemical calculations	44
Editorial Board	44
Table of contents	44