OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Tile by tile: capturing the evolutionary mosaic of human conditions	109
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	66
Editorial overview: evolutionary genetics: how a tiny model system enables big discoveries	64
Inheritance of epigenetic transcriptional memory	61
Editorial Board	55
RNA in chromatin organization and nuclear architecture	55
Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations	48
Editorial Board	46
Integrative approaches to study enhancer–promoter communication	43
Why is measuring and predicting fitness under genomic conflict so hard?	40
Editorial Board	39
Cell identity conversion in liver regeneration after injury	37
Editorial Board	37
Editorial overview: New insights into epithelial dynamics: From tissue homeostasis to morphogenesis	36
Maternal genetic factors in the development of congenital heart defects	33
Discrete roles for Rad54 and Rdh54 during homologous recombination	32
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends	32
Ex situ-armus: experimental models for combating respiratory dysfunction	31
Chromatin architecture reorganization during somatic cell reprogramming	31
Editorial Board	30
Epithelial–immune crosstalk in health and disease	30
In vivo conversion of dopamine neurons in mouse models of Parkinson’s disease — a future approach for regenerative therapy?	29
Transposable elements in early human embryo development and embryo models	28
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	28
Trends and variation in vertebrate patterns as outcomes of self-organization	27

Clinical evaluation of patients with a neuropsychiatric risk copy number variant	26
A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila	26
Recent insights into N6-methyladenosine during viral infection	24
Clinical Perspectives in Epitranscriptomics	24
DNA helicases in homologous recombination repair	24
Role of RNA modifications in cancer metastasis	23
Spatial metabolomics in tissue injury and regeneration	23
Mechanisms of maternal intergenerational epigenetic inheritance	23
Homologous recombination within repetitive DNA	22
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	22
The origins of cancer cell dormancy	22
Quantitative mapping of the mammalian epitranscriptome	22
From Aedes to Zeugodacus: a review of dipteran body coloration studies regarding evolutionary developmental biology, pest control, and species discovery	22
Advances in skeletal genomics research across tissues and cells	21
Cancer epitranscriptomics in a nutshell	21
H3–H4 histone chaperones and cancer	21
The X chromosome in C. elegans sex determination and dosage compensation	20
Refining the role of N6-methyladenosine in cancer	20
Human-specific genetic modifiers of cortical architecture and function	20
How gene duplication diversifies the landscape of protein oligomeric state and function	20
Deciphering microglia phenotypes in health and disease	19
Break-induced replication mechanisms in yeast and mammals	19
Chromatin and aberrant enhancer activity in KMT2A rearranged acute lymphoblastic leukemia	19
Crosstalk between histone/DNA modifications and RNA N6-methyladenosine modification	19
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	19
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	19
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	19
Evolution of short linear motifs and disordered proteins Topic: yeast as model system to study evolution	18
Editorial overview: Conflicts, conflicts everywhere	18
Making region-specific integumentary organs in birds: evolution and modifications	18
Approaches to probe and perturb long noncoding RNA functions in diseases	18
Shaping the mouse heart tube from the second heart field epithelium	17
Human blastoid as an in vitro model of human blastocysts	17
DNA end resection during homologous recombination	17
Unveiling the potential: implications of successful somatic cell-to-ganglion organoid reprogramming	16
Editorial Board	16
Cellular plasticity in the neural crest and cancer	16
How our brains are built: emerging approaches to understand human-specific features	16
Centromere drive: chromatin conflict in meiosis	16
In vitro models of pre- and post-gastrulation embryonic development	15
Marvels of spiny mouse regeneration: cellular players and their interactions in restoring tissue architecture in mammals	15
Evolutionary dynamics between transposable elements and their host genomes: mechanisms of suppression and escape	15
Therapeutic strategies to target the epitranscriptomic machinery	15
The stochastic nature of genome organization and function	15
16p11.2 deletion syndrome	15
Epigenetic dynamics during germline development: insights from Drosophila and C. elegans	15
‘Enhancing’ skeletal muscle and stem cells in three-dimensions: genome regulation of skeletal muscle in development and disease	15
Recent progress in understanding the genomic architecture of sexual conflict	15
Key mechanisms and in vitro reconstitution of fetal oocyte development in mammals	14
A GC-centered view of 3D genome organization	14

NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	14
Cell cycle dynamics and developmental dynamics of the 3D genome: toward linking the two timescales	14
Interplay between N-adenosine RNA methylation and mRNA splicing	14
Architecture of RNA–RNA interactions	14
Editorial overview: Cool, colorful, and complex animal systems	13
Amending the injured heart by in vivo reprogramming	13
Resources and challenges for integrative analysis of nuclear architecture data	13
High-throughput approaches to functional characterization of genetic variation in yeast	13
Genetic clues to reprogramming power and formation of mouse oocyte	12
Chromosomal instability as a source of genomic plasticity	12
Structural and functional brain alterations revealed by neuroimaging in CNV carriers	12
In vitro dynamics of DNA loop extrusion by structural maintenance of chromosomes complexes	12
Timing Drosophila development through steroid hormone action	12
Molecular genetic mechanisms of dilated cardiomyopathy	12
RNA editing and immune control: from mechanism to therapy	12
Pediatric CNS cancer genomics and immunogenomics	12
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	12
Understanding and evolving prions by yeast multiplexed assays	12
Adipocyte gene expression in obesity — insights gained and challenges ahead	11
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	11
Epigenetic memory in reprogramming	11
Human embryo models: the importance of national policy and governance review	11
Insights into homology search from cryo-EM structures of RecA-DNA recombination intermediates	11
Dissecting the complexity of CNV pathogenicity: insights from Drosophila and zebrafish models	11
The shifting shape of genomes: dynamics of heterochromatin interactions at the nuclear lamina	11
Editorial Board	11
Reprogramming of pancreatic islet cells for regeneration and rejuvenation	11
Revealing epithelial morphogenetic mechanisms through live imaging	11
Editorial overview: Understanding the biology of cancer genomes in the context of DNA, RNA, histone marks, and 3D chromatin organization	11
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	11
Diversification of the vertebrate limb: sequencing the events	11
Predicting immunotherapy response through genomics	10
Regional patterning and regulation of melanin pigmentation in insects	10
Somatic copy number variants in neuropsychiatric disorders	10
Active nematics across scales from cytoskeleton organization to tissue morphogenesis	10
Control of structure-specific endonucleases during homologous recombination in eukaryotes	10
Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming	10
Corneal regeneration: insights in epithelial stem cell heterogeneity and dynamics	10
Experimental evolution of drug resistance in human fungal pathogens	10
Modeling X-chromosome inactivation and reactivation during human development	10
Replication timing and transcriptional control: beyond cause and effect — part IV	10
Correlation between protein abundance and sequence conservation: what do recent experiments say?	10
7q11.23 deletion and duplication	10
Toward the dissection of hematopoietic stem cell fates and their determinants	10
Evolution of pigment cells and patterns: recent insights from teleost fishes	10
Editorial Board	10
Emergence of the circadian clock oscillation during the developmental process in mammals	10