OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Editorial Board	76
Editorial Board	50
Editorial Board	48
Why is measuring and predicting fitness under genomic conflict so hard?	47
Editorial overview: Conflicts, conflicts everywhere	47
Integrative approaches to study enhancer–promoter communication	40
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	40
DNA end resection during homologous recombination	40
R-loops in neurodegeneration	39
Tile by tile: capturing the evolutionary mosaic of human conditions	39
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	37
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	36
The X chromosome in C. elegans sex determination and dosage compensation	33
Epithelial–immune crosstalk in health and disease	33
Break-induced replication mechanisms in yeast and mammals	32
Editorial Board	30
In vitro models of pre- and post-gastrulation embryonic development	29
Genetic clues to reprogramming power and formation of mouse oocyte	28
Therapeutic strategies to target the epitranscriptomic machinery	28
Control of cell fate upon transcription factor–driven cardiac reprogramming	28
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	28
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	27
Interplay between N-adenosine RNA methylation and mRNA splicing	27
Epigenetic memory in reprogramming	26
Single-cell genomic profiling to study regeneration	26

High-throughput approaches to functional characterization of genetic variation in yeast	26
Toward the dissection of hematopoietic stem cell fates and their determinants	26
Reprogramming lineage identity through cell–cell fusion	26
If you please, draw me a neuron — linking evolutionary tinkering with human neuron evolution	25
Using human pluripotent stem cells to dissect trophoblast development	25
Adipose tissue-derived lipokines in metabolism	24
Editorial Board	24
Stem-cell-based human and mouse embryo models	24
Cell–cell interactions between transplanted retinal organoid cells and recipient tissues	24
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing	24
Something old, something new, something borrowed, something red: the origin of ecologically relevant novelties in Hemiptera	24
Recombination-mediated genome rearrangements	24
Molecular genetics of pulmonary hypertension in children	23
Better together: how cooperativity influences transcriptional bursting	23
Transposon waves at the water-to-land transition	23
How strand exchange protein function benefits from ATP hydrolysis	23
Editorial overview: Recombination — the ends justify the means	22
Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomics	22
Editorial overview: Drivers, droplets, and deeds of nuclear genome organization	22
Dynamic microenvironments shape nuclear organization and gene expression	22
Editorial overview: Multiscale regulation of genome folding in space, time, and across the tree of life	21
Digesting the mechanobiology of the intestinal epithelium	20
Modifying gastruloids to dissect mechanisms of tissue-specific induction	20
Intestinal epithelial organoids: regeneration and maintenance of the intestinal epithelium	20
Nuclear remodeling during cell fate transitions	20
Enhancers on the edge — how the nuclear envelope controls gene regulatory elements	19
Eco-evo-devo advances with butterfly eyespots	19
Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?	19
Human 8-cell embryo-like cells from pluripotent stem cells	18
Recipes and ingredients for deep learning models of 3D genome folding	18
Multi-organelle-mediated mRNA localization in neurons and links to disease	18
Evolution of 3D chromatin organization at different scales	17
Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution	17
What are tethering elements?	17
A haystack in the needle: packaging sperm DNA in insects	17
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs	17
The Yin and Yang of replicative aging and rejuvenation	17
Shaping inheritance: how distinct reproductive strategies influence DNA methylation memory in plants	16
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	16
DNA helicases in homologous recombination repair	16
Biological roles of nonsense-mediated RNA decay: insights from the nervous system	16
Epigenetic priming in the male germline	16
Chromatin architecture reorganization during somatic cell reprogramming	16
RNA interference therapeutics for cardiac regeneration	16
Maternal genetic factors in the development of congenital heart defects	16
Editorial Board	16
Cell identity conversion in liver regeneration after injury	16
Approaches to probe and perturb long noncoding RNA functions in diseases	15
Discrete roles for Rad54 and Rdh54 during homologous recombination	15
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	15

Transposable elements in early human embryo development and embryo models	14
Advances in skeletal genomics research across tissues and cells	14
Deciphering microglia phenotypes in health and disease	14
Editorial Board	13
Trends and variation in vertebrate patterns as outcomes of self-organization	13
Rewiring cancer: 3D genome determinants of cancer hallmarks	13
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	13
Cellular and developmental basis of avian structural coloration	13
Amending the injured heart by in vivo reprogramming	13
Inheritance of epigenetic transcriptional memory	13
Cellular plasticity in the neural crest and cancer	13
A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila	13
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	13
Adipose tissue lipid metabolism: lipolysis	13
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	13
Correlation between protein abundance and sequence conservation: what do recent experiments say?	13
Editorial overview: Regaining architecture and cell cross-talk upon regeneration	13
Regional patterning and regulation of melanin pigmentation in insects	13
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	13
The stem cell zoo for comparative studies of developmental tempo	12
Editorial overview: The genome in space–time	12
Dissecting nephron morphogenesis using kidney organoids from human pluripotent stem cells	12
Editorial Board	12
Brain organoids: the quest to decipher human-specific features of brain development	12
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes	12
Principles of genome activation in the early embryo	12
Architecture of RNA–RNA interactions	12
Evolution of sexual development and sexual dimorphism in insects	12
Alternative splicing in addiction	12
Toward a comprehensive view of gene architecture during transcription	12
Cellular identity through the lens of direct lineage reprogramming	12
Recent developments in adipose tissue-secreted factors and their target organs	12
Evolution and molecular bases of reproductive isolation	12
Genome folding dynamics during the M-to-G1-phase transition	12
Phase separation and inheritance of repressive chromatin domains	11
Epistasis and evolutionary dependencies in human cancers	11
In vitro models of human hypoblast and mouse primitive endoderm	11
Mechanism of mitotic recombination: insights from C. elegans	11
Topical section: embryonic models (2023) for Current Opinion in Genetics & Development	11
Reconstitution of reproductive organ system that produces functional oocytes	11
The role of loop extrusion in enhancer-mediated gene activation	11
An extending ATR–CHK1 circuitry: the replication stress response and beyond	11
Exploring conditional gene essentiality through systems genetics approaches in yeast	11
Transcriptional regulation of T cell metabolism and metabolic control of T cell gene expression	11
The role of SAF-A/hnRNP U in regulating chromatin structure	11
Seasonal plasticity: how do butterfly wing pattern traits evolve environmental responsiveness?	11
Microbial experimental evolution in a massively multiplexed and high-throughput era	11
Bridging spatial and temporal scales of developmental gene regulation	11
3D chromosomal architecture in germinal center B cells and its alterations in lymphomagenesis	11
Oncogenic fusion proteins and their role in three-dimensional chromatin structure, phase separation, and cancer	11
Editorial Board	11
The role of tissue maturity and mechanical state in controlling cell extrusion	11
Editorial Board	11