OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Epithelial–immune crosstalk in health and disease	70
Editorial Board	69
Editorial Board	62
Editorial Board	48
Why is measuring and predicting fitness under genomic conflict so hard?	43
Integrative approaches to study enhancer–promoter communication	42
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	42
Editorial overview: Conflicts, conflicts everywhere	39
Tile by tile: capturing the evolutionary mosaic of human conditions	39
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	36
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	35
The X chromosome in C. elegans sex determination and dosage compensation	34
Break-induced replication mechanisms in yeast and mammals	33
DNA end resection during homologous recombination	32
Editorial Board	32
In vitro models of pre- and post-gastrulation embryonic development	31
Epigenetic memory in reprogramming	31
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	29
Control of cell fate upon transcription factor–driven cardiac reprogramming	28
Toward the dissection of hematopoietic stem cell fates and their determinants	26
High-throughput approaches to functional characterization of genetic variation in yeast	26
Interplay between N-adenosine RNA methylation and mRNA splicing	26
Genetic clues to reprogramming power and formation of mouse oocyte	26
Structural and functional brain alterations revealed by neuroimaging in CNV carriers	25
Therapeutic strategies to target the epitranscriptomic machinery	25

Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	25
Cell–cell interactions between transplanted retinal organoid cells and recipient tissues	24
Reprogramming lineage identity through cell–cell fusion	24
Single-cell genomic profiling to study regeneration	23
Using human pluripotent stem cells to dissect trophoblast development	23
Recombination-mediated genome rearrangements	23
If you please, draw me a neuron — linking evolutionary tinkering with human neuron evolution	23
Adipose tissue-derived lipokines in metabolism	23
Editorial Board	22
Something old, something new, something borrowed, something red: the origin of ecologically relevant novelties in Hemiptera	22
Transposon waves at the water-to-land transition	22
Better together: how cooperativity influences transcriptional bursting	22
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing	22
How strand exchange protein function benefits from ATP hydrolysis	22
Molecular genetics of pulmonary hypertension in children	22
Stem-cell-based human and mouse embryo models	21
Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomics	21
Dynamic microenvironments shape nuclear organization and gene expression	21
Nuclear remodeling during cell fate transitions	20
Editorial overview: Multiscale regulation of genome folding in space, time, and across the tree of life	20
Modifying gastruloids to dissect mechanisms of tissue-specific induction	20
Editorial overview: Drivers, droplets, and deeds of nuclear genome organization	20
Eco-evo-devo advances with butterfly eyespots	20
Editorial overview: Recombination — the ends justify the means	20
Recipes and ingredients for deep learning models of 3D genome folding	19
Human 8-cell embryo-like cells from pluripotent stem cells	18
Enhancers on the edge — how the nuclear envelope controls gene regulatory elements	18
Digesting the mechanobiology of the intestinal epithelium	18
Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?	18
Copy number variants in neurexin genes: phenotypes and mechanisms	18
Intestinal epithelial organoids: regeneration and maintenance of the intestinal epithelium	18
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs	17
Evolution of 3D chromatin organization at different scales	17
What are tethering elements?	17
RNA interference therapeutics for cardiac regeneration	17
Epigenetic priming in the male germline	16
Maternal genetic factors in the development of congenital heart defects	16
Discrete roles for Rad54 and Rdh54 during homologous recombination	16
Shaping inheritance: how distinct reproductive strategies influence DNA methylation memory in plants	16
Inheritance of epigenetic transcriptional memory	16
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	15
Editorial Board	15
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	15
Cell identity conversion in liver regeneration after injury	15
Rewiring cancer: 3D genome determinants of cancer hallmarks	15
DNA helicases in homologous recombination repair	15
Transposable elements in early human embryo development and embryo models	14
Chromatin architecture reorganization during somatic cell reprogramming	14
Deciphering microglia phenotypes in health and disease	14
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	14

A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila	14
Approaches to probe and perturb long noncoding RNA functions in diseases	14
Correlation between protein abundance and sequence conservation: what do recent experiments say?	13
Trends and variation in vertebrate patterns as outcomes of self-organization	13
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	13
Advances in skeletal genomics research across tissues and cells	13
Editorial Board	13
Editorial overview: Regaining architecture and cell cross-talk upon regeneration	13
Cellular plasticity in the neural crest and cancer	13
Cellular and developmental basis of avian structural coloration	12
Architecture of RNA–RNA interactions	12
7q11.23 deletion and duplication	12
Editorial overview: The genome in space–time	12
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	12
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	12
Adipose tissue lipid metabolism: lipolysis	12
Regional patterning and regulation of melanin pigmentation in insects	12
Amending the injured heart by in vivo reprogramming	12
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes	11
Evolution and molecular bases of reproductive isolation	11
Principles of genome activation in the early embryo	11
Brain organoids: the quest to decipher human-specific features of brain development	11
Exploring conditional gene essentiality through systems genetics approaches in yeast	11
In vitro models of human hypoblast and mouse primitive endoderm	11
Dissecting nephron morphogenesis using kidney organoids from human pluripotent stem cells	11
The stem cell zoo for comparative studies of developmental tempo	11
Toward a comprehensive view of gene architecture during transcription	11
Evolution of sexual development and sexual dimorphism in insects	11
3D chromosomal architecture in germinal center B cells and its alterations in lymphomagenesis	11
Microbial experimental evolution in a massively multiplexed and high-throughput era	11
Genome folding dynamics during the M-to-G1-phase transition	11
Epistasis and evolutionary dependencies in human cancers	11
Recent developments in adipose tissue-secreted factors and their target organs	11
Cellular identity through the lens of direct lineage reprogramming	11
Editorial Board	11
The role of loop extrusion in enhancer-mediated gene activation	11
Phase separation and inheritance of repressive chromatin domains	11
Oncogenic fusion proteins and their role in three-dimensional chromatin structure, phase separation, and cancer	11