OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Editorial Board	72
Editorial Board	72
Editorial overview: Conflicts, conflicts everywhere	55
Editorial Board	55
Why is measuring and predicting fitness under genomic conflict so hard?	50
The X chromosome in C. elegans sex determination and dosage compensation	49
Integrative approaches to study enhancer–promoter communication	40
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	38
R-loops in neurodegeneration	37
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	36
Evolution and ecology of commensal gut protists: recent advances	33
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	33
Convergence and divergence of molecular phenotypes in iPSC-derived models of 16p11.2 and 22q11.2 reciprocal copy number variants	32
Tile by tile: capturing the evolutionary mosaic of human conditions	32
Epithelial–immune crosstalk in health and disease	30
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	30
Editorial Board	30
Therapeutic strategies to target the epitranscriptomic machinery	29
Genetic clues to reprogramming power and formation of mouse oocyte	28
Interplay between N-adenosine RNA methylation and mRNA splicing	28
Exploring the origin of the development: totipotent stem cells	28
High-throughput approaches to functional characterization of genetic variation in yeast	27
In vitro models of pre- and post-gastrulation embryonic development	27
Control of cell fate upon transcription factor–driven cardiac reprogramming	26
Toward the dissection of hematopoietic stem cell fates and their determinants	26

Single-cell genomic profiling to study regeneration	25
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	25
If you please, draw me a neuron — linking evolutionary tinkering with human neuron evolution	24
Using human pluripotent stem cells to dissect trophoblast development	24
Cell–cell interactions between transplanted retinal organoid cells and recipient tissues	24
Transposon waves at the water-to-land transition	23
Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomics	23
Molecular genetics of pulmonary hypertension in children	23
Recent advances in the neurogenomics of autism spectrum disorder	23
Adipose tissue-derived lipokines in metabolism	23
Stem-cell-based human and mouse embryo models	22
Dynamic microenvironments shape nuclear organization and gene expression	22
Genome instability in mammalian embryos implications for genome editing, development, and evolution	22
Editorial Board	22
Better together: how cooperativity influences transcriptional bursting	22
Emerging oligo-based imaging methods to study chromatin organization in cells and tissue	21
Genetic disruption of nonsense-mediated mRNA decay in neurodevelopmental disorders	21
Behavioral evolution by diverging cell type composition	21
At the tip of regeneration	20
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing	20
Editorial Board	19
Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?	19
Human 8-cell embryo-like cells from pluripotent stem cells	19
Editorial overview: Drivers, droplets, and deeds of nuclear genome organization	19
Editorial overview: Multiscale regulation of genome folding in space, time, and across the tree of life	19
Enhancers on the edge — how the nuclear envelope controls gene regulatory elements	18
Chromosome organization by Structural Maintenance of Chromosomes complexes in C. elegans	18
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs	17
Shaping inheritance: how distinct reproductive strategies influence DNA methylation memory in plants	17
Mechanisms of lung regeneration and repair	17
Nuclear remodeling during cell fate transitions	17
Intestinal epithelial organoids: regeneration and maintenance of the intestinal epithelium	17
Recipes and ingredients for deep learning models of 3D genome folding	17
Epigenetic priming in the male germline	17
Modifying gastruloids to dissect mechanisms of tissue-specific induction	17
A haystack in the needle: packaging sperm DNA in insects	17
Integrating multiomic layers to decode psychiatric disease mechanisms	17
The Yin and Yang of replicative aging and rejuvenation	17
Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution	17
Multi-organelle-mediated mRNA localization in neurons and links to disease	17
Linking phenotype to genotype using comprehensive genomic comparisons	17
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	16
Biological roles of nonsense-mediated RNA decay: insights from the nervous system	16
Maternal genetic factors in the development of congenital heart defects	16
Transposable elements in early human embryo development and embryo models	16
Inheritance of epigenetic transcriptional memory	16
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	16
What are tethering elements?	16
Editorial Board	16
Approaches to probe and perturb long noncoding RNA functions in diseases	16

Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	16
Rewiring cancer: 3D genome determinants of cancer hallmarks	16
Evolution of 3D chromatin organization at different scales	16
Cell identity conversion in liver regeneration after injury	16
Deciphering microglia phenotypes in health and disease	16
Advances in skeletal genomics research across tissues and cells	16
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	16
Decoding schizophrenia through postmortem human brain transcriptomics	15
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	15
Cooperativity between regulatory elements acts as a modulator of enhancer function	15
Editorial Board	15
Adipose tissue lipid metabolism: lipolysis	14
Amending the injured heart by in vivo reprogramming	14
Correlation between protein abundance and sequence conservation: what do recent experiments say?	14
Mix-and-match between transposable elements and zinc finger proteins fuels genic and regulatory innovation	14
Editorial overview: Regaining architecture and cell cross-talk upon regeneration	14
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	14
Cellular plasticity in the neural crest and cancer	14
Recent developments in adipose tissue-secreted factors and their target organs	13
Evolutionary genetics meets ecological immunology: insights into the evolution of immune systems	13
Editorial Board	13
Epistasis and evolutionary dependencies in human cancers	13
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes	13
The stem cell zoo for comparative studies of developmental tempo	13
Evolution and molecular bases of reproductive isolation	13
Oncogenic fusion proteins and their role in three-dimensional chromatin structure, phase separation, and cancer	13
Phase separation and inheritance of repressive chromatin domains	13
Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks	13
Editorial overview: The genome in space–time	13
Brain organoids: the quest to decipher human-specific features of brain development	13
Principles of genome activation in the early embryo	13
Genome folding dynamics during the M-to-G1-phase transition	13
The role of loop extrusion in enhancer-mediated gene activation	13
Deep learning for psychiatric genomics: from tools to applications	13
Toward a comprehensive view of gene architecture during transcription	13