OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-03-01 to 2025-03-01.)

Article	Citations
Editorial Board	127
Editorial overview: evolutionary genetics: how a tiny model system enables big discoveries	77
Editorial Board	66
Editorial Board	61
Integrative approaches to study enhancer–promoter communication	59
Why is measuring and predicting fitness under genomic conflict so hard?	52
Editorial Board	45
Editorial Board	45
Editorial overview: New insights into epithelial dynamics: From tissue homeostasis to morphogenesis	44
Maternal genetic factors in the development of congenital heart defects	43
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends	41
Editorial Board	38
Ex situ-armus: experimental models for combating respiratory dysfunction	38
Epithelial–immune crosstalk in health and disease	36
Transposable elements in early human embryo development and embryo models	35
In vivo conversion of dopamine neurons in mouse models of Parkinson’s disease — a future approach for regenerative therapy?	35
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	35
Spatial metabolomics in tissue injury and regeneration	33
Clinical Perspectives in Epitranscriptomics	33
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	30
Quantitative mapping of the mammalian epitranscriptome	30
Clinical evaluation of patients with a neuropsychiatric risk copy number variant	29
A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila	28
Mechanisms of maternal intergenerational epigenetic inheritance	28
From Aedes to Zeugodacus: a review of dipteran body coloration studies regarding evolutionary developmental biology, pest control, and species discovery	26

DNA end resection during homologous recombination	26
Making region-specific integumentary organs in birds: evolution and modifications	26
Break-induced replication mechanisms in yeast and mammals	26
Homologous recombination within repetitive DNA	26
DNA helicases in homologous recombination repair	25
Chromatin architecture reorganization during somatic cell reprogramming	24
Cell identity conversion in liver regeneration after injury	23
The origins of cancer cell dormancy	23
Shaping the mouse heart tube from the second heart field epithelium	22
Evolution of short linear motifs and disordered proteins Topic: yeast as model system to study evolution	22
Trends and variation in vertebrate patterns as outcomes of self-organization	22
The X chromosome in C. elegans sex determination and dosage compensation	22
Discrete roles for Rad54 and Rdh54 during homologous recombination	22
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	22
Human-specific genetic modifiers of cortical architecture and function	21
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	21
Approaches to probe and perturb long noncoding RNA functions in diseases	21
Recent insights into N6-methyladenosine during viral infection	21
RNA in chromatin organization and nuclear architecture	21
Chromatin and aberrant enhancer activity in KMT2A rearranged acute lymphoblastic leukemia	21
Role of RNA modifications in cancer metastasis	20
Unveiling the potential: implications of successful somatic cell-to-ganglion organoid reprogramming	20
Inheritance of epigenetic transcriptional memory	20
Tile by tile: capturing the evolutionary mosaic of human conditions	19
How our brains are built: emerging approaches to understand human-specific features	19
Deciphering microglia phenotypes in health and disease	19
H3–H4 histone chaperones and cancer	19
Human blastoid as an in vitro model of human blastocysts	19
Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations	19
Cancer epitranscriptomics in a nutshell	18
Refining the role of N6-methyladenosine in cancer	18
Advances in skeletal genomics research across tissues and cells	18
How gene duplication diversifies the landscape of protein oligomeric state and function	17
Corneal regeneration: insights in epithelial stem cell heterogeneity and dynamics	17
Crosstalk between histone/DNA modifications and RNA N6-methyladenosine modification	17
Editorial overview: Conflicts, conflicts everywhere	17
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	17
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	17
Epigenetic memory in reprogramming	16
Editorial Board	16
Exploiting the plasticity of cholangiocytes to repair the biliary tree	16
Timing Drosophila development through steroid hormone action	15
Adipose tissue lipid metabolism: lipolysis	15
Adipocyte gene expression in obesity — insights gained and challenges ahead	15
Editorial Board	15
Chromosomal instability as a source of genomic plasticity	15
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	15
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	14
Editorial overview: Understanding the biology of cancer genomes in the context of DNA, RNA, histone marks, and 3D chromatin organization	14
Active nematics across scales from cytoskeleton organization to tissue morphogenesis	14

Correlation between protein abundance and sequence conservation: what do recent experiments say?	14
Editorial Board	14
Pediatric CNS cancer genomics and immunogenomics	14
Therapeutic strategies to target the epitranscriptomic machinery	13
Understanding and evolving prions by yeast multiplexed assays	13
Marvels of spiny mouse regeneration: cellular players and their interactions in restoring tissue architecture in mammals	13
Human embryo models: the importance of national policy and governance review	13
Interplay between N-adenosine RNA methylation and mRNA splicing	12
Cellular and developmental basis of avian structural coloration	12
16p11.2 deletion syndrome	12
Key mechanisms and in vitro reconstitution of fetal oocyte development in mammals	12
7q11.23 deletion and duplication	12
Genetic approaches to revealing the principles of nuclear architecture	12
Somatic copy number variants in neuropsychiatric disorders	12
Resources and challenges for integrative analysis of nuclear architecture data	12
Structural and functional brain alterations revealed by neuroimaging in CNV carriers	12
Regional patterning and regulation of melanin pigmentation in insects	11
Toward the dissection of hematopoietic stem cell fates and their determinants	11
Dissecting the complexity of CNV pathogenicity: insights from Drosophila and zebrafish models	11
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	11
Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming	11
Revealing epithelial morphogenetic mechanisms through live imaging	11
Insights into homology search from cryo-EM structures of RecA-DNA recombination intermediates	11
Emerging interactions between RNA methylation and chromatin architecture	11
High-throughput approaches to functional characterization of genetic variation in yeast	11
Editorial overview: Cool, colorful, and complex animal systems	11
The stochastic nature of genome organization and function	11
Distinct fibroblasts in scars and regeneration	11
Control of cell fate upon transcription factor–driven cardiac reprogramming	11
Control of structure-specific endonucleases during homologous recombination in eukaryotes	10
Experimental evolution of drug resistance in human fungal pathogens	10
Epithelial morphogenesis in organoids	10
Centromere drive: chromatin conflict in meiosis	10
Amending the injured heart by in vivo reprogramming	10
Molecular genetic mechanisms of dilated cardiomyopathy	10
In vitro models of pre- and post-gastrulation embryonic development	10
Epigenetic dynamics during germline development: insights from Drosophila and C. elegans	10
Cellular plasticity in the neural crest and cancer	10
Recent progress in understanding the genomic architecture of sexual conflict	10
Evolutionary dynamics between transposable elements and their host genomes: mechanisms of suppression and escape	10
May the best wound WIHN: the hallmarks of wound-induced hair neogenesis	10
Replication timing and transcriptional control: beyond cause and effect — part IV	10
Reprogramming of pancreatic islet cells for regeneration and rejuvenation	10
A GC-centered view of 3D genome organization	10
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	10
Cell cycle dynamics and developmental dynamics of the 3D genome: toward linking the two timescales	10