OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Enhancer-promoter communication: hubs or loops?	83
The role of 3D chromatin domains in gene regulation: a multi-facetted view on genome organization	64
Spatially resolved transcriptomics and its applications in cancer	59
Role of VPS13, a protein with similarity to ATG2, in physiology and disease	48
Chromosome dynamics during interphase: a biophysical perspective	47
Specialized functions of cohesins STAG1 and STAG2 in 3D genome architecture	45
CTCF and CTCFL in cancer	45
To loop or not to loop: what is the role of TADs in enhancer function and gene regulation?	44
Evolution of sexual development and sexual dimorphism in insects	44
Diverse lncRNA mechanisms in brain development and disease	43
The many faces of Polycomb regulation by RNA	42
Single-molecule tracking of transcription protein dynamics in living cells: seeing is believing, but what are we seeing?	41
Evolution of the mutation rate across primates	41
16p11.2 deletion syndrome	40
Copy number variation and neuropsychiatric illness	39
Regulation of 3D chromatin organization by CTCF	39
Microexons: at the nexus of nervous system development, behaviour and autism spectrum disorder	36
Advances in colon cancer research: in vitro and animal models	35
Evolution of pigment cells and patterns: recent insights from teleost fishes	35
4D nucleome modeling	35
Structure-forming repeats and their impact on genome stability	33
Epigenetic regulation of mouse preimplantation embryo development	31
The evolution of the human brain and disease susceptibility	30
African population history: an ancient DNA perspective	30
Microglial ontogeny, diversity and neurodevelopmental functions	30

Advances in repeat expansion diseases and a new concept of repeat motif–phenotype correlation	30
Nuclear mechanisms of gene expression control: pre-mRNA splicing as a life or death decision	29
The role of clustered protocadherins in neurodevelopment and neuropsychiatric diseases	29
Extrachromosomal DNA (ecDNA) in cancer pathogenesis	28
Diagnostic genetic testing for neurodevelopmental psychiatric disorders: closing the gap between recommendation and clinical implementation	28
New gene discoveries highlight functional convergence in autism and related neurodevelopmental disorders	28
Mesoscale organization of the chromatin fiber	27
The self-stirred genome: large-scale chromatin dynamics, its biophysical origins and implications	27
An extending ATR–CHK1 circuitry: the replication stress response and beyond	27
Generations of genomes: advances in paleogenomics technology and engagement for Indigenous people of the Americas	26
The shifting shape of genomes: dynamics of heterochromatin interactions at the nuclear lamina	26
Poison exons in neurodevelopment and disease	26
A cell in hand is worth two in the embryo: recent advances in 2-cell like cell reprogramming	26
The evolution of structural colour in butterflies	26
Exosomes in cancer development	25
Rising from the ashes: cellular senescence in regeneration	25
Break-induced replication mechanisms in yeast and mammals	25
The nuclear pore complex and the genome: organizing and regulatory principles	24
Disentangling the paradox of the PCDH19 clustering epilepsy, a disorder of cellular mosaics	23
Experimental embryology of gastrulation: pluripotent stem cells as a new model system	23
The transcription factor code in iPSC reprogramming	23
Activity regulates brain development in the fly	23
Cortico-basal ganglia circuits underlying dysfunctional control of motor behaviors in neuropsychiatric disorders	23
Biophysical mechanisms of chromatin patterning	23
Inferring evolutionary dynamics of mutation rates through the lens of mutation spectrum variation	23
LINC complex regulation of genome organization and function	22
The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization	21
Mechanisms of maternal intergenerational epigenetic inheritance	21
Insights into clonal hematopoiesis and its relation to cancer risk	20
DNA end resection during homologous recombination	20
Waiting on the Fringe: cell autonomy and signaling delays in segmentation clocks	20
Human adaptation over the past 40,000 years	20
The role of somatic mosaicism in brain disease	20
Differential 3D chromatin organization and gene activity in genomic imprinting	20
Control of cell shape during epithelial morphogenesis: recent advances	19
Genetic pathways involved in human speech disorders	19
Replication stress: from chromatin to immunity and beyond	19
Serine ADP-ribosylation in DNA-damage response regulation	19
Mitotic recombination in yeast: what we know and what we don’t know	19
Active nematics across scales from cytoskeleton organization to tissue morphogenesis	19
Molecular mechanisms for targeted ASD treatments	18
Update on Müller glia regenerative potential for retinal repair	18
Prime time for primate functional genomics	18
The dynamics of chromatin architecture in brain development and function	18
Digesting the mechanobiology of the intestinal epithelium	18
Xeno-organ donor pigs with multiple genetic modifications – the more the better?	18
The dawn of non-human primate models for neurodevelopmental disorders	18
Evo-devo of shell colour in gastropods and bivalves	18
The evolution of post-translational modifications	18
The stochastic nature of genome organization and function	18

H3–H4 histone chaperones and cancer	18
Stabilizing hematopoietic stem cells in vitro	17
Linking genotype, cell behavior, and phenotype: multidisciplinary perspectives with a basis in zebrafish patterns	17
Homologous recombination within repetitive DNA	17
Engineering and modeling of multicellular morphologies and patterns	17
Human evolutionary history in Eastern Eurasia using insights from ancient DNA	17
RAD51 paralog function in replicative DNA damage and tolerance	17
Distinct fibroblasts in scars and regeneration	17
Cellular and developmental basis of avian structural coloration	16
The role of SAF-A/hnRNP U in regulating chromatin structure	16
Olfactory receptor choice: a case study for gene regulation in a multi-enhancer system	16
Noncanonical imprinting: intergenerational epigenetic inheritance mediated by Polycomb complexes	16
The WRN helicase: resolving a new target in microsatellite unstable cancers	16
Collective effects in epithelial cell death and cell extrusion	16
Recombination and restart at blocked replication forks	16
Latest trends in archaeogenetic research of west Eurasians	16
How gene duplication diversifies the landscape of protein oligomeric state and function	16
The use of CRISPR/Cas9-based gene editing strategies to explore cancer gene function in mice	16
Recent insights into zebrafish cardiac regeneration	16
Pigmentation and color pattern diversity in Odonata	15
The role of loop extrusion in enhancer-mediated gene activation	15
Structural and functional brain alterations revealed by neuroimaging in CNV carriers	15
Regeneration in the spiny mouse, Acomys, a new mammalian model	15
What a finding of gene copy number variation can add to the diagnosis of developmental neuropsychiatric disorders	15
Somatic variants in epilepsy – advancing gene discovery and disease mechanisms	15
Mechanical induction and competence in epithelial morphogenesis	15
ERK signaling dynamics in the morphogenesis and homeostasis of Drosophila	15
Multi-scale dynamics of heterochromatin repair	14
Gene regulation by non-coding RNAs in the 3D genome architecture	14
Single cell analysis pushes the boundaries of TAD formation and function	14
Chromosomal instability as a source of genomic plasticity	14
Histone isoforms and the oncohistone code	14
The X chromosome in C. elegans sex determination and dosage compensation	14
Challenges of diagnostic genomics in Latin America	13
Homologous recombination deficiency: how genomic signatures are generated	13
7q11.23 deletion and duplication	13
All for one and one for all: heterogeneity of genetic etiologies in neurodevelopmental psychiatric disorders	13
Lighting up single-mRNA translation dynamics in living cells	13
Metal ion availability and homeostasis as drivers of metabolic evolution and enzyme function	13