OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Editorial Board	60
Editorial Board	55
Integrative approaches to study enhancer–promoter communication	51
Editorial overview: Conflicts, conflicts everywhere	50
Editorial Board	49
Why is measuring and predicting fitness under genomic conflict so hard?	44
Evolution and ecology of commensal gut protists: recent advances	41
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	39
Tile by tile: capturing the evolutionary mosaic of human conditions	38
Epithelial–immune crosstalk in health and disease	37
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	36
The X chromosome in C. elegans sex determination and dosage compensation	34
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	33
R-loops in neurodegeneration	31
Editorial Board	30
Therapeutic strategies to target the epitranscriptomic machinery	29
Control of cell fate upon transcription factor–driven cardiac reprogramming	28
Exploring the origin of the development: totipotent stem cells	28
Genetic clues to reprogramming power and formation of mouse oocyte	28
In vitro models of pre- and post-gastrulation embryonic development	28
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	28
Toward the dissection of hematopoietic stem cell fates and their determinants	27
High-throughput approaches to functional characterization of genetic variation in yeast	27
Interplay between N-adenosine RNA methylation and mRNA splicing	27
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	27

Using human pluripotent stem cells to dissect trophoblast development	25
Single-cell genomic profiling to study regeneration	25
Better together: how cooperativity influences transcriptional bursting	23
Cell–cell interactions between transplanted retinal organoid cells and recipient tissues	23
Genetic disruption of nonsense-mediated mRNA decay in neurodevelopmental disorders	23
If you please, draw me a neuron — linking evolutionary tinkering with human neuron evolution	23
Behavioral evolution by diverging cell type composition	22
Transposon waves at the water-to-land transition	22
Genome instability in mammalian embryos implications for genome editing, development, and evolution	22
Molecular genetics of pulmonary hypertension in children	22
Dynamic microenvironments shape nuclear organization and gene expression	21
Adipose tissue-derived lipokines in metabolism	21
Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomics	21
Stem-cell-based human and mouse embryo models	21
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing	21
The Yin and Yang of replicative aging and rejuvenation	20
Editorial overview: Drivers, droplets, and deeds of nuclear genome organization	20
Editorial Board	19
Nuclear remodeling during cell fate transitions	19
Enhancers on the edge — how the nuclear envelope controls gene regulatory elements	19
A haystack in the needle: packaging sperm DNA in insects	19
Modifying gastruloids to dissect mechanisms of tissue-specific induction	18
Editorial overview: Multiscale regulation of genome folding in space, time, and across the tree of life	18
Recipes and ingredients for deep learning models of 3D genome folding	17
Human 8-cell embryo-like cells from pluripotent stem cells	17
Multi-organelle-mediated mRNA localization in neurons and links to disease	17
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs	16
Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution	16
Intestinal epithelial organoids: regeneration and maintenance of the intestinal epithelium	16
Evolution of 3D chromatin organization at different scales	16
What are tethering elements?	16
Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?	16
Linking phenotype to genotype using comprehensive genomic comparisons	16
Shaping inheritance: how distinct reproductive strategies influence DNA methylation memory in plants	16
Epigenetic priming in the male germline	16
Digesting the mechanobiology of the intestinal epithelium	16
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	15
Rewiring cancer: 3D genome determinants of cancer hallmarks	15
Editorial Board	15
Biological roles of nonsense-mediated RNA decay: insights from the nervous system	15
Maternal genetic factors in the development of congenital heart defects	15
Advances in skeletal genomics research across tissues and cells	15
Approaches to probe and perturb long noncoding RNA functions in diseases	14
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	14
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	14
Editorial overview: Regaining architecture and cell cross-talk upon regeneration	14
Transposable elements in early human embryo development and embryo models	14
Cell identity conversion in liver regeneration after injury	14
Editorial Board	14
Cellular plasticity in the neural crest and cancer	14

Deciphering microglia phenotypes in health and disease	14
Inheritance of epigenetic transcriptional memory	14
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	14
Correlation between protein abundance and sequence conservation: what do recent experiments say?	14
Architecture of RNA–RNA interactions	14
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	14
Adipose tissue lipid metabolism: lipolysis	13
Evolution and molecular bases of reproductive isolation	13
Recent developments in adipose tissue-secreted factors and their target organs	13
Editorial overview: The genome in space–time	13
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	13
Evolutionary genetics meets ecological immunology: insights into the evolution of immune systems	13
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes	13
Principles of genome activation in the early embryo	13
Mix-and-match between transposable elements and zinc finger proteins fuels genic and regulatory innovation	13
Toward a comprehensive view of gene architecture during transcription	13
The stem cell zoo for comparative studies of developmental tempo	13
Brain organoids: the quest to decipher human-specific features of brain development	13
Amending the injured heart by in vivo reprogramming	13
Dissecting nephron morphogenesis using kidney organoids from human pluripotent stem cells	12
Phase separation and inheritance of repressive chromatin domains	12
Genome folding dynamics during the M-to-G1-phase transition	12
Alternative splicing in addiction	12
Oncogenic fusion proteins and their role in three-dimensional chromatin structure, phase separation, and cancer	12
Editorial Board	12
In vitro models of human hypoblast and mouse primitive endoderm	12
The role of loop extrusion in enhancer-mediated gene activation	12
Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks	12
3D chromosomal architecture in germinal center B cells and its alterations in lymphomagenesis	12
Exploring conditional gene essentiality through systems genetics approaches in yeast	12
Microbial experimental evolution in a massively multiplexed and high-throughput era	12
Bridging spatial and temporal scales of developmental gene regulation	12