OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Genetics & Development is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Editorial Board	82
Editorial overview: Conflicts, conflicts everywhere	74
Editorial Board	59
Why is measuring and predicting fitness under genomic conflict so hard?	55
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	53
Tile by tile: capturing the evolutionary mosaic of human conditions	51
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	42
Evolution and ecology of commensal gut protists: recent advances	40
R-loops in neurodegeneration	39
Integrative approaches to study enhancer–promoter communication	38
Convergence and divergence of molecular phenotypes in iPSC-derived models of 16p11.2 and 22q11.2 reciprocal copy number variants	36
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	34
Editorial Board	33
High-throughput approaches to functional characterization of genetic variation in yeast	31
Genetic clues to reprogramming power and formation of mouse oocyte	31
Exploring the origin of the development: totipotent stem cells	31
Control of cell fate upon transcription factor–driven cardiac reprogramming	30
In vitro models of pre- and post-gastrulation embryonic development	29
Toward the dissection of hematopoietic stem cell fates and their determinants	29
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	28
Therapeutic strategies to target the epitranscriptomic machinery	27
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	27
Single-cell genomic profiling to study regeneration	27
Interplay between N-adenosine RNA methylation and mRNA splicing	27
Long-term evolution of regulatory DNA sequences. Part 1: simulations on global, biophysically-realistic genotype–phenotype maps	26

Dynamic microenvironments shape nuclear organization and gene expression	26
Using human pluripotent stem cells to dissect trophoblast development	26
Cell–cell interactions between transplanted retinal organoid cells and recipient tissues	26
If you please, draw me a neuron — linking evolutionary tinkering with human neuron evolution	26
Recent advances in the neurogenomics of autism spectrum disorder	26
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing	26
At the tip of regeneration	25
Better together: how cooperativity influences transcriptional bursting	25
Emerging oligo-based imaging methods to study chromatin organization in cells and tissue	24
Genome instability in mammalian embryos implications for genome editing, development, and evolution	24
Behavioral evolution by diverging cell type composition	24
Editorial Board	24
Genetic disruption of nonsense-mediated mRNA decay in neurodevelopmental disorders	23
Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomics	23
Progress toward complete cell-type and spatial-resolution atlases of the developing brain	21
Somatic variation in multiple sclerosis: from blood to brain	20
Editorial overview: Drivers, droplets, and deeds of nuclear genome organization	20
Stem-cell-based human and mouse embryo models	20
Adipose tissue-derived lipokines in metabolism	20
Transposon waves at the water-to-land transition	20
Molecular genetics of pulmonary hypertension in children	20
Editorial overview: Multiscale regulation of genome folding in space, time, and across the tree of life	19
Intestinal epithelial organoids: regeneration and maintenance of the intestinal epithelium	19
Human 8-cell embryo-like cells from pluripotent stem cells	19
Editorial Board	19
Nuclear remodeling during cell fate transitions	19
Enhancers on the edge — how the nuclear envelope controls gene regulatory elements	19
Modifying gastruloids to dissect mechanisms of tissue-specific induction	19
The Yin and Yang of replicative aging and rejuvenation	19
Chromosome organization by Structural Maintenance of Chromosomes complexes in C. elegans	19
Recipes and ingredients for deep learning models of 3D genome folding	18
Active processes shape and move the genome and nucleoplasm	18
A haystack in the needle: packaging sperm DNA in insects	18
Integrating multiomic layers to decode psychiatric disease mechanisms	18
The emergence of neurogenic lineage motifs in building the vertebrate retina	18
Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?	18
Mechanisms of lung regeneration and repair	18
Reassessing forebrain organization: recent evidence challenges the prosomere model	18
Linking phenotype to genotype using comprehensive genomic comparisons	18
Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution	17
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	17
Advances in skeletal genomics research across tissues and cells	17
Multi-organelle-mediated mRNA localization in neurons and links to disease	17
Shaping inheritance: how distinct reproductive strategies influence DNA methylation memory in plants	17
Evolution of 3D chromatin organization at different scales	17
Maternal genetic factors in the development of congenital heart defects	17
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs	17
What are tethering elements?	17
Editorial Board	17
Epigenetic priming in the male germline	17

Biological roles of nonsense-mediated RNA decay: insights from the nervous system	17
Deciphering microglia phenotypes in health and disease	16
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	16
Editorial Board	16
Approaches to probe and perturb long noncoding RNA functions in diseases	16
Cell identity conversion in liver regeneration after injury	16
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	16
Rewiring cancer: 3D genome determinants of cancer hallmarks	16
Transposable elements in early human embryo development and embryo models	16
Inheritance of epigenetic transcriptional memory	16
Clonal analysis for understanding fate biases in developing embryos	16
Editorial overview: Regaining architecture and cell cross-talk upon regeneration	15
Decoding schizophrenia through postmortem human brain transcriptomics	15
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	15
Amending the injured heart by in vivo reprogramming	15
Cellular plasticity in the neural crest and cancer	15
Correlation between protein abundance and sequence conservation: what do recent experiments say?	15
The stem cell zoo for comparative studies of developmental tempo	14
Evolutionary genetics meets ecological immunology: insights into the evolution of immune systems	14
Mix-and-match between transposable elements and zinc finger proteins fuels genic and regulatory innovation	14
Evolution and molecular bases of reproductive isolation	14
Recent developments in adipose tissue-secreted factors and their target organs	14
Long-term evolution of regulatory DNA sequences. Part 2: theory and future challenges	14
Toward a comprehensive view of gene architecture during transcription	14
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	14
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes	14
Lineage tracing in gastruloids to understand determinants of early fate decisions	14
Brain organoids: the quest to decipher human-specific features of brain development	14
Editorial overview: The genome in space–time	14
Adipose tissue lipid metabolism: lipolysis	14
Cooperativity between regulatory elements acts as a modulator of enhancer function	14
Microbial experimental evolution in a massively multiplexed and high-throughput era	14
Principles of genome activation in the early embryo	14
Editorial overview: Evolutionary genetics (2025): mapping the molecular basis of phenotypic divergence	14