Current Opinion in Genetics & Development

Article	Citations
Editorial Board	76
Editorial Board	50
Editorial Board	48
Editorial overview: Conflicts, conflicts everywhere	47
Why is measuring and predicting fitness under genomic conflict so hard?	47
Integrative approaches to study enhancer–promoter communication	40
A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation	40
DNA end resection during homologous recombination	40
Tile by tile: capturing the evolutionary mosaic of human conditions	39
R-loops in neurodegeneration	39
Loops, crosstalk, and compartmentalization: it takes many layers to regulate DNA methylation	37
Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity	36
Epithelial–immune crosstalk in health and disease	33
The X chromosome in C. elegans sex determination and dosage compensation	33
Break-induced replication mechanisms in yeast and mammals	32
Editorial Board	30
In vitro models of pre- and post-gastrulation embryonic development	29
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate	28
Genetic clues to reprogramming power and formation of mouse oocyte	28
Therapeutic strategies to target the epitranscriptomic machinery	28
Control of cell fate upon transcription factor–driven cardiac reprogramming	28
Interplay between N-adenosine RNA methylation and mRNA splicing	27
NAT10 and cytidine acetylation in mRNA: intersecting paths in development and disease	27
Toward the dissection of hematopoietic stem cell fates and their determinants	26
Reprogramming lineage identity through cell–cell fusion	26

Epigenetic memory in reprogramming	26
Single-cell genomic profiling to study regeneration	26
High-throughput approaches to functional characterization of genetic variation in yeast	26
If you please, draw me a neuron — linking evolutionary tinkering with human neuron evolution	25
Using human pluripotent stem cells to dissect trophoblast development	25
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing	24
Something old, something new, something borrowed, something red: the origin of ecologically relevant novelties in Hemiptera	24
Recombination-mediated genome rearrangements	24
Adipose tissue-derived lipokines in metabolism	24
Editorial Board	24
Stem-cell-based human and mouse embryo models	24
Cell–cell interactions between transplanted retinal organoid cells and recipient tissues	24
Molecular genetics of pulmonary hypertension in children	23
Better together: how cooperativity influences transcriptional bursting	23
Transposon waves at the water-to-land transition	23
How strand exchange protein function benefits from ATP hydrolysis	23
Editorial overview: Drivers, droplets, and deeds of nuclear genome organization	22
Dynamic microenvironments shape nuclear organization and gene expression	22
Editorial overview: Recombination — the ends justify the means	22
Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomics	22
Editorial overview: Multiscale regulation of genome folding in space, time, and across the tree of life	21
Nuclear remodeling during cell fate transitions	20
Digesting the mechanobiology of the intestinal epithelium	20
Modifying gastruloids to dissect mechanisms of tissue-specific induction	20
Intestinal epithelial organoids: regeneration and maintenance of the intestinal epithelium	20
Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?	19
Enhancers on the edge — how the nuclear envelope controls gene regulatory elements	19
Eco-evo-devo advances with butterfly eyespots	19
Multi-organelle-mediated mRNA localization in neurons and links to disease	18
Human 8-cell embryo-like cells from pluripotent stem cells	18
Recipes and ingredients for deep learning models of 3D genome folding	18
Meiotic drive of noncentromeric loci in mammalian meiosis II eggs	17
The Yin and Yang of replicative aging and rejuvenation	17
Evolution of 3D chromatin organization at different scales	17
Editorial overview: Peering into our history through a genetic lens: How advances in genetics are changing our understanding of human evolution	17
What are tethering elements?	17
A haystack in the needle: packaging sperm DNA in insects	17
Maternal genetic factors in the development of congenital heart defects	16
Editorial Board	16
Cell identity conversion in liver regeneration after injury	16
Shaping inheritance: how distinct reproductive strategies influence DNA methylation memory in plants	16
Cancer-associated chromatin variants uncover the oncogenic role of transposable elements	16
DNA helicases in homologous recombination repair	16
Biological roles of nonsense-mediated RNA decay: insights from the nervous system	16
Epigenetic priming in the male germline	16
Chromatin architecture reorganization during somatic cell reprogramming	16
RNA interference therapeutics for cardiac regeneration	16
Editorial overview: Epigenetic inheritance: A shortcut to environmental adaptation?	15
Approaches to probe and perturb long noncoding RNA functions in diseases	15
Discrete roles for Rad54 and Rdh54 during homologous recombination	15

Deciphering microglia phenotypes in health and disease	14
Transposable elements in early human embryo development and embryo models	14
Advances in skeletal genomics research across tissues and cells	14
Trends and variation in vertebrate patterns as outcomes of self-organization	13
Correlation between protein abundance and sequence conservation: what do recent experiments say?	13
Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease	13
Regional patterning and regulation of melanin pigmentation in insects	13
A new era of understanding in vivo metabolic flux in thermogenic adipocytes	13
Inheritance of epigenetic transcriptional memory	13
Editorial Board	13
A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila	13
Rewiring cancer: 3D genome determinants of cancer hallmarks	13
Cellular and developmental basis of avian structural coloration	13
Amending the injured heart by in vivo reprogramming	13
Songbird germline-restricted chromosome as a potential arena of genetic conflicts	13
Cellular plasticity in the neural crest and cancer	13
Editorial overview: Regaining architecture and cell cross-talk upon regeneration	13
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations	13
Adipose tissue lipid metabolism: lipolysis	13
The stem cell zoo for comparative studies of developmental tempo	12
Editorial overview: The genome in space–time	12
Dissecting nephron morphogenesis using kidney organoids from human pluripotent stem cells	12
Editorial Board	12
Brain organoids: the quest to decipher human-specific features of brain development	12
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes	12
Principles of genome activation in the early embryo	12
Architecture of RNA–RNA interactions	12
Evolution of sexual development and sexual dimorphism in insects	12
Alternative splicing in addiction	12
Toward a comprehensive view of gene architecture during transcription	12
Cellular identity through the lens of direct lineage reprogramming	12
Recent developments in adipose tissue-secreted factors and their target organs	12
Evolution and molecular bases of reproductive isolation	12
Genome folding dynamics during the M-to-G1-phase transition	12
Phase separation and inheritance of repressive chromatin domains	11
Epistasis and evolutionary dependencies in human cancers	11
In vitro models of human hypoblast and mouse primitive endoderm	11
Mechanism of mitotic recombination: insights from C. elegans	11
Topical section: embryonic models (2023) for Current Opinion in Genetics & Development	11
Reconstitution of reproductive organ system that produces functional oocytes	11
The role of loop extrusion in enhancer-mediated gene activation	11
An extending ATR–CHK1 circuitry: the replication stress response and beyond	11
Exploring conditional gene essentiality through systems genetics approaches in yeast	11
Transcriptional regulation of T cell metabolism and metabolic control of T cell gene expression	11
The role of SAF-A/hnRNP U in regulating chromatin structure	11
Seasonal plasticity: how do butterfly wing pattern traits evolve environmental responsiveness?	11
Microbial experimental evolution in a massively multiplexed and high-throughput era	11
Bridging spatial and temporal scales of developmental gene regulation	11
3D chromosomal architecture in germinal center B cells and its alterations in lymphomagenesis	11
Oncogenic fusion proteins and their role in three-dimensional chromatin structure, phase separation, and cancer	11
Editorial Board	11
The role of tissue maturity and mechanical state in controlling cell extrusion	11
Editorial Board	11
Chromosome organization in 4D: insights from C. elegans development	10
When 3D genome changes cause disease: the impact of structural variations in congenital disease and cancer	10
The metabolic baton: conducting the dance of N6-methyladenosine writing and erasing	10
Can we stop one heart from breaking: triumphs and challenges in cardiac reprogramming	10
Proliferation and dissemination of killer meiotic drive loci	10
Polycomb complexes in MLL–AF9-related leukemias	10
Jack of all trades versus master of one: how generalist versus specialist strategies of transposable elements relate to their horizontal transfer between lineages	10
Timing mechanisms: insights from comparative neural differentiation systems	10
Paternal genome elimination: patterns and mechanisms of drive and silencing	10
In search of conserved principles of planar cell polarization	10
Cellular diversity and developmental hierarchy in the planarian nervous system	10
Hijacked enhancer–promoter and silencer–promoter loops in cancer	9
The transcription factor code in iPSC reprogramming	9
Spliceosome complex and neurodevelopmental disorders	9
To splice or not to splice: pseudoexons in neurological disease and opportunities for intervention	9
The power of proximity: mechanisms and biological roles of transvection	9
Recent advances in stem cell-based blastocyst models	9
Principles of long-range gene regulation	9
Transposon persistence and control in germ cells	9
Pigmentation and color pattern diversity in Odonata	9
Prospects for precision genetic medicine in congenital heart disease	9
R-loop homeostasis in genome dynamics, gene expression and development	9
The genetic landscape of cardiovascular left–right patterning defects	9
Quantitative mapping of the mammalian epitranscriptome	9
Ex situ-armus: experimental models for combating respiratory dysfunction	8
Pediatric CNS cancer genomics and immunogenomics	8
Epigenetic dynamics during germline development: insights from Drosophila and C. elegans	8

Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming	8
Clinical Perspectives in Epitranscriptomics	8
Unlocking regeneration: how partial reprogramming resembles tissue healing	8
Experimental evolution of drug resistance in human fungal pathogens	8
Decoding N6-methyladenosine’s dynamic role in stem cell fate and early embryo development: insights into RNA–chromatin interactions	8
Making region-specific integumentary organs in birds: evolution and modifications	8
Modification of the RNA methylome in neurodevelopmental disorders	8
Temporal patterning of the vertebrate developing neural tube	8
Evolutionary neurogenomics at single-cell resolution	7
Xenotransplantation — a shortcut to construct tissue complexity in organoids	7
Circuit integration by transplanted human neurons	7
Non-model systems in mammalian forelimb evo-devo	7
Recent insights into the in vitro culture systems for mammalian embryos	7
The WRN helicase: resolving a new target in microsatellite unstable cancers	7
Female meiotic drive in plants: mechanisms and dynamics	7
Reprogramming cellular identity during intestinal regeneration	7
Epithelial folding determines the final shape of beetle horns	7
Recent insights into the evolution of mutation rates in yeast	7
Vascular and immune interactions in islets transplantation and 3D islet models	7
Editorial Board	7
Chromosomal instability as a source of genomic plasticity	7
Do sex-linked male meiotic drivers contribute to intrinsic hybrid incompatibilities? Recent empirical studies from flies and rodents	7
Mechanisms of regulatory evolution in yeast	7
Interplay of transposable elements and ageing: epigenetic regulation and potential epitranscriptomic influence	7
The ribonucleoprotein network of the nucleus: a historical perspective	7
Overcoming muscle stem cell aging	7
Mitochondrial curation for the next generation	7
Distinct fibroblasts in scars and regeneration	7
Corneal regeneration: insights in epithelial stem cell heterogeneity and dynamics	7
Pluripotent stem cell–derived mesenchymal stem cells for therapeutic applications, developmental study, and cancer research	7
The ever-growing world of gastruloids: autogenous models of mammalian embryogenesis	6
Recombination-dependent replication: new perspectives from site-specific fork barriers	6
Transgenerational epigenetic control of constitutive heterochromatin, transposons, and centromeres	6
Narrative engineering of the liver	6
A new era in neuromuscular junction research: current advances in self-organized and assembled in vitro models	6
Deciphering the role of structural variation in human evolution: a functional perspective	6
NOVA1/2 genes and alternative splicing in neurodevelopment	6
Network models of chromatin structure	6
Metabolic regulation of cardiac regeneration: roles of hypoxia, energy homeostasis, and mitochondrial dynamics	6
Therapeutic index of targeting select chromatin complexes in human cancer patients	6
Extending the spectrum in aortopathy: stenosis to aneurysm	6
Engineering immune organoids to regenerate host immune system	6
Early central nervous system development and neuron regeneration	6
Advancements in inner ear development, regeneration, and repair through otic organoids	6
Insights into multilevel spatial regulation within the root stem cell niche	6
Factors that determine cell type–specific CTCF binding in health and disease	6
Linking mitochondria metabolism, developmental timing, and human brain evolution	6
Concepts, mechanisms and implications of long-term epigenetic inheritance	6
Adipocyte plasticity in tissue regeneration, repair, and disease	6
Extracellular vesicles for remote brain repair	6
Editorial overview: Early embryonic development models: back to the beginning	5
A lifelong duty: how Xist maintains the inactive X chromosome	5
Rethinking chromatin accessibility: from compaction to dynamic interactions	5
Plasticity of muscle stem cells in homeostasis and aging	5
Spatial orchestration of the genome: topological reorganisation during X-chromosome inactivation	5
A finger on the pulse of regeneration: insights into the cellular mechanisms of adult digit tip regeneration	5
RAD51 paralog function in replicative DNA damage and tolerance	5
The evolution and genetics of lepidopteran egg and caterpillar coloration	5
Editorial overview: New insights into epithelial dynamics: From tissue homeostasis to morphogenesis	5
Safeguarding the epigenome through the cell cycle: a multitasking game	5
Genomic snowflakes: how the uniqueness of DNA folding allows us to smell the chemical universe	5
Somatic mutation burden in relation to aging and functional life span: implications for cellular reprogramming and rejuvenation	5
Decoding the role of tRNA modifications in cancer progression	5
When and why are mitochondria paternally inherited?	5
Multi-scale dynamics of heterochromatin repair	5
Human trophoblast stem cell-state acquisition from pluripotent stem cells and somatic cells	5
Molecular mechanisms of the specialization of human synapses in the neocortex	5