Current Opinion in Biotechnology

Article	Citations
Editorial Board	262
Editorial Board	211
Bioelectrosynthesis systems	126
Corrigendum to “Methylotrophs: from C1 compounds to food” [Curr Opin Biotechnol 75 (2022) 102685]	121
Synthetic biology advances towards a bio-based society in the era of artificial intelligence	116
Tumor lipid metabolism: a mechanistic link between diet and cancer progression	115
Creating value from purple phototrophic bacteria via single-cell protein production	106
Stem cells characterization: OMICS reinforcing analytics	104
Cell-free technologies for biopharmaceutical research and production	99
Recent progress in the synthesis of advanced biofuel and bioproducts	96
The osteo-angiogenic signaling crosstalk for bone regeneration: harmony out of complexity	95
Anaerobic microbial methanol utilization as a one-carbon feedstock	94
The journey of a lifetime — development of Pfizer’s COVID-19 vaccine	90
How much could improving photosynthesis increase crop yields? A call for systems-level perspectives to guide engineering strategies	89
Applications of artificial intelligence to enzyme and pathway design for metabolic engineering	85
Systems biology-based analysis of cell-free systems	82
Editorial Board	71
A molecular assessment of the practical potential of DNA-based computation	70
Recent advances, opportunities and challenges in cybergenetic identification and control of biomolecular networks	68
Engineered T cells and macrophages: two arms to seize solid tumors	66
Engineered living bioassemblies for biomedical and functional material applications	64
Coupling chemistry and biology for the synthesis of advanced bioproducts	63
The plant microbiota: composition, functions, and engineering	60
Bridging the gap — biomimetic design of bioelectronic interfaces	58
Lighting the way: recent developments and applications in molecular optogenetics	56

Editorial Board	54
Innovations and trends in antibody repertoire analysis	53
Deep learning in regulatory genomics: from identification to design	53
Single-cell analysis opens a goldmine for plant functional studies	53
Whole-plant phenotypic engineering: moving beyond ratios for multi-objective optimization of nutrient use efficiency	53
Emerging technologies for genetic control systems in cellular therapies	53
Genetically encoded elastin-like polypeptide nanoparticles for drug delivery	52
Leveraging rAAV bioprocess understanding and next generation bioanalytics development	52
Engineering of the genetic code	51
Dietary microalgae on poultry meat and eggs: explained versus unexplained effects	50
Computational tools and resources for designing new pathways to small molecules	50
Using genome and transcriptome analysis to elucidate biosynthetic pathways	49
Biocatalytic cascade transformations for the synthesis of C-nucleosides and N-nucleoside analogs	48
Multifaceted metabolic role of infections in the tumor microenvironment	47
2-hydroxyglutarate rides the cancer-immunity cycle	46
Mass spectrometry imaging methods for visualizing tumor heterogeneity	45
Machine learning to navigate fitness landscapes for protein engineering	45
Emerging trends in production of plant natural products and new-to-nature biopharmaceuticals in yeast	45
Editorial Board	44
Editorial overview: Biotechnological insights of marine and terrestrial microbiome	44
Perspectives for self-driving labs in synthetic biology	44
Plant synthetic biology as a tool to help eliminate hidden hunger	44
Tissue engineering in the agri-food industry: current status, socio-economic overview and regulatory compliance	43
Toolboxes for plant systems biology research	43
Analytics of host cell proteins (HCPs): lessons from biopharmaceutical mAb analysis for Gene therapy products	43
Anaerobic fluorescent reporters for cell identification, microbial cell biology and high-throughput screening of microbiota and genomic libraries	42
Harnessing the potential of microbial methane utilization for chasing sustainability	42
Reducing crop losses by gene-editing control of organ developmental physiology	42
Corrigendum to: “Design, construction, and application of noncanonical redox cofactor infrastructures” [Curr Opin Biotechnol 84 (2023) 103019]	41
Editorial overview: Emerging routes to sustainable energy capture and conversion into value-added products	41
Advancing in vivo reprogramming with synthetic biology	41
The potential of amoeba-based processes for natural product syntheses	41
Matching diverse feedstocks to conversion processes for the future bioeconomy	41
Single-cell omics analysis with genome-scale metabolic modeling	40
Metabolic and cellular engineering for the production of natural products	40
Synthetic apomixis: the beginning of a new era	40
Impact of anthropogenic contamination on glacier surface biota	40
Sourcing DNA parts for synthetic biology applications in plants	40
Biochemical production with microbial bioelectrochemical systems	39
Pathway engineering for the biosynthesis of psychedelics	39
Editorial overview: Pioneering innovations in food biotechnology	39
Synthetic biology approaches for dynamic CHO cell engineering	38
Understanding atmospheric intercontinental dispersal of harmful microorganisms	38
Low-cost, point-of-care biomarker quantification	38
Redox as a bioprocess parameter: analytical redox quantification in biological therapeutic production	38
Editorial Board	37
Editorial overview: Nanobiotechnology for immunoengineering	37
Engineered methane biocatalysis: strategies to assimilate methane for chemical production	37
Editorial Board	37
Synthetic mRNA – emerging new class of drug for tissue regeneration	37

Antigen-specific nanomedicines for the treatment of autoimmune disease: target cell types, mechanisms and outcomes	36
Next-generation biological vector platforms for in vivo delivery of genome editing agents	36
Extracellular vesicles as therapeutics for inflammation and infection	36
Targeting ripening regulators to develop fruit with high quality and extended shelf life	36
Understanding and harnessing the complexity of interspecies interactions in acetogenic mixotrophic co-cultures	36
Strategies and opportunities for engineering antifungal peptides for therapeutic applications	36
Potential use of microbial engineering in single-cell protein production	35
Matchmaking at the cell surface using bispecifics to put cells on their best behavior	35
The aging tumor metabolic microenvironment	35
What’s new in single-cell proteomics	35
Operation at thermophilic temperatures: an underestimated asset for gas fermentation processes	35
Complexity of subcellular metabolism: strategies for compartment-specific profiling	34
Strategies for uncovering stable isotope tracing patterns between cell populations	34
Programmable synthetic biology tools for developing microbial cell factories	34
Synthetic fuels: what are they and where do they come from?	34
Biotechnology approaches for natural product discovery, engineering, and production based on Burkholderia bacteria	34
Editorial Board	34
Beyond vancomycin: recent advances in the modification, reengineering, production and discovery of improved glycopeptide antibiotics to tackle multidrug-resistant bacteria	33
Editorial Board	33
Bridging the gender gap in autoimmunity with T-cell–targeted biomaterials	32
Can digital twin efforts shape microorganism-based alternative food?	32
Biohybrid approaches to interface with the nervous system: the best of both worlds	32
De novo domestication: retrace the history of agriculture to design future crops	32
Optimizing the value of bioinks and robotics to advance in vivo bioprinting	32
Challenges and future perspectives for high-throughput chimeric antigen receptor T cell discovery	32
Microbiological food safety considerations in shelf-life extension of fresh fruits and vegetables	32
Engineering bacterial warriors: harnessing microbes to modulate animal physiology	32
Engineering plant–microbe communication for plant nutrient use efficiency	31
Machine learning for predicting phenotype from genotype and environment	31
Editorial overview: Tissue, cell, and pathway engineering	31
Inhalable mRNA vaccines for respiratory diseases: a roadmap	31
An integrated eco-evolutionary framework to predict population-level responses of climate-sensitive pathogens	31
Practical monitoring technologies for cells and substrates in biomanufacturing	31
Analytical tools for unravelling the metabolism of gas-fermenting Clostridia	31
Editorial Board	31
Decoding dissolved information: environmental DNA sequencing at global scale to monitor a changing ocean	30
Quantitative and analytical tools to analyze the spatiotemporal population dynamics of microbial consortia	30
Corrigendum to “Unraveling the mechanobiology of immune cells” [Curr Opin Biotechnol 66 (2020) 236-245]	29
Progress and challenges in the translation of cancer nanomedicines	29
Two in one: the emerging concept of bifunctional antibodies	29
Clustered regularly interspaced short palindromic repeats tools for plant metabolic engineering: achievements and perspectives	29
Biologics-based degraders — an expanding toolkit for targeted-protein degradation	28
Sustainability in food-waste reduction biotechnology: a critical review	28
General framework for enzyme-photo-coupled catalytic system toward carbon dioxide conversion	28
Advances in engineering substrate scope of Pseudomonas cell factories	28
Mycotoxin risks are lower in biotech corn	28
Searching for the optimal microbial factory: high-throughput biosensors and analytical techniques for screening small molecules	28
Recent trends in the modification of polyphenolic compounds using hydroxylation and glycosylation	28
Engineering next-generation chimeric antigen receptor-T cells: recent breakthroughs and remaining challenges in design and screening of novel chimeric antigen receptor variants	27
Cell-free synthesis of industrial chemicals and biofuels from carbon feedstocks	27
Advances in engineering and optimization of transcription factor-based biosensors for plug-and-play small molecule detection	27
Senescent cells in tissue engineering	27
Division of labor for substrate utilization in natural and synthetic microbial communities	26
Hitting the sweet spot with capillary electrophoresis: advances in N-glycomics and glycoproteomics	26
Achieving net zero CO2 emission in the biobased production of reduced platform chemicals using defined co-feeding of methanol	26
In situ characterization of the tumor microenvironment	26
Genetic and process engineering for polyhydroxyalkanoate production from pre- and post-consumer food waste	26
Proteomics insights into the fungal-mediated bioremediation of environmental contaminants	25
Computational models in systems biology: standards, dissemination, and best practices	25
Force in numbers: high-throughput screening approaches to unlock microbial transport	25
Recent advances in microbial production of rare sugars and steviols	25
Path to zero emission of nitrous oxide in sewage treatment: is nitrification controllable or avoidable?	25
Recent advances in microbial synthesis of polyphenols	25
Advances in engineering algae for biofuel production	25
Integrating bioprinting and optogenetic technologies for precision plant tissue engineering	25
Chemical speciation of trace metals in mammalian cell culture media: looking under the hood to boost cellular performance and product quality	24
Carbon recycling with synthetic CO2 fixation pathways	24
Engineering organoids as cerebral disease models	24
Combining enzyme and metabolic engineering for microbial supply of therapeutic phytochemicals	24
Quantifying nanoparticle delivery: challenges, tools, and advances	24
Engineering bacteria for cancer immunotherapy	24
Drugging the microbiome and bacterial live biotherapeutic consortium production	24
Cellobiose dehydrogenase in biofuel cells	24
Biomolecular feedback controllers: from theory to applications	23
Pleiotropy, a feature or a bug? Toward co-ordinating plant growth, development, and environmental responses through engineering plant hormone signaling	23
Cell-free enzyme cascades — application and transition from development to industrial implementation	23
Machine learning applications to improve flavor and nutritional content of horticultural crops through breeding and genetics	23
Approaches for a more microbiologically and chemically safe dried fruit supply chain	23
Cytochromes P450 in the biocatalytic valorization of lignin	23
Engineering microbial consortia with rationally designed cellular interactions	23

Anaerobic microbial core for municipal wastewater treatment — the sustainable platform for resource recovery	23
In vivo 2H/13C flux analysis in metabolism research	23
Continuous biomanufacturing with microbes — upstream progresses and challenges	23
Microbial production of chemicals driven by CRISPR-Cas systems	22
Building mutational bridges between carbohydrate-active enzymes	22
Editorial overview: Tissue, cell and pathway engineering: bioinspired, biomimetic and hybrid neural interfaces	22
Window of sustainable bioprocess operation: towards merging environmental sustainability assessment and process operation at early-stage bioprocess development	22
Machine learning in wastewater: opportunities and challenges — “not everything is a nail!”	22
Getting better all the time — recent progress in the development of CRISPR/Cas-based tools for plant genome engineering	22
Editorial overview: Phosphate Special Issue	22
Antimicrobial polymeric biomaterials based on synthetic, nanotechnology, and biotechnological approaches	22
Time to integrate biotechnological approaches into fish gut microbiome research	22
Editorial Board	22
Technologies for the discovery of G protein–coupled receptor–targeting biologics	22
Optogenetics in medicine: innovations and therapeutic applications	22