Current Opinion in Biotechnology

Article	Citations
Editorial Board	276
Editorial Board	223
Corrigendum to “Methylotrophs: from C1 compounds to food” [Curr Opin Biotechnol 75 (2022) 102685]	133
Tumor lipid metabolism: a mechanistic link between diet and cancer progression	125
How much could improving photosynthesis increase crop yields? A call for systems-level perspectives to guide engineering strategies	122
Systems biology-based analysis of cell-free systems	121
Bioelectrosynthesis systems	118
Cell-free technologies for biopharmaceutical research and production	111
The journey of a lifetime — development of Pfizer’s COVID-19 vaccine	104
Synthetic biology advances towards a bio-based society in the era of artificial intelligence	103
Anaerobic microbial methanol utilization as a one-carbon feedstock	102
Creating value from purple phototrophic bacteria via single-cell protein production	98
The osteo-angiogenic signaling crosstalk for bone regeneration: harmony out of complexity	97
Recent progress in the synthesis of advanced biofuel and bioproducts	95
Applications of artificial intelligence to enzyme and pathway design for metabolic engineering	90
Engineered living bioassemblies for biomedical and functional material applications	89
Leveraging rAAV bioprocess understanding and next generation bioanalytics development	78
Editorial Board	76
Editorial Board	75
Bridging the gap — biomimetic design of bioelectronic interfaces	72
A molecular assessment of the practical potential of DNA-based computation	71
Whole-plant phenotypic engineering: moving beyond ratios for multi-objective optimization of nutrient use efficiency	68
Recent advances, opportunities and challenges in cybergenetic identification and control of biomolecular networks	64
Deep learning in regulatory genomics: from identification to design	63
Coupling chemistry and biology for the synthesis of advanced bioproducts	58

Single-cell analysis opens a goldmine for plant functional studies	58
Emerging technologies for genetic control systems in cellular therapies	56
Microfluidics meets cell-free systems: from molecular engineering to synthetic cells	56
Innovations and trends in antibody repertoire analysis	56
Lighting the way: recent developments and applications in molecular optogenetics	55
Genetically encoded elastin-like polypeptide nanoparticles for drug delivery	55
Molecular methods for high-throughput, multiplexed, and automated genome editing in prokaryotes and eukaryotes	55
Engineered T cells and macrophages: two arms to seize solid tumors	54
The plant microbiota: composition, functions, and engineering	53
Biocatalytic cascade transformations for the synthesis of C-nucleosides and N-nucleoside analogs	52
Computational tools and resources for designing new pathways to small molecules	51
Machine learning to navigate fitness landscapes for protein engineering	51
Perspectives for self-driving labs in synthetic biology	49
Using genome and transcriptome analysis to elucidate biosynthetic pathways	49
Strategies for engineering domesticated and undomesticated human microbes	49
2-hydroxyglutarate rides the cancer-immunity cycle	49
Multifaceted metabolic role of infections in the tumor microenvironment	49
Engineering of the genetic code	48
Dietary microalgae on poultry meat and eggs: explained versus unexplained effects	47
Mass spectrometry imaging methods for visualizing tumor heterogeneity	47
Emerging trends in production of plant natural products and new-to-nature biopharmaceuticals in yeast	47
Matching diverse feedstocks to conversion processes for the future bioeconomy	46
Editorial overview: Biotechnological insights of marine and terrestrial microbiome	46
Reducing crop losses by gene-editing control of organ developmental physiology	46
Toolboxes for plant systems biology research	46
Tissue engineering in the agri-food industry: current status, socio-economic overview and regulatory compliance	46
Advancing in vivo reprogramming with synthetic biology	46
Editorial Board	46
Harnessing the potential of microbial methane utilization for chasing sustainability	45
Plant synthetic biology as a tool to help eliminate hidden hunger	45
Sourcing DNA parts for synthetic biology applications in plants	43
Corrigendum to: “Design, construction, and application of noncanonical redox cofactor infrastructures” [Curr Opin Biotechnol 84 (2023) 103019]	43
Synthetic biology approaches for dynamic CHO cell engineering	43
Low-cost, point-of-care biomarker quantification	43
Building trust in automated experimentation: uncertainty quantification in the era of high-throughput biolabs	43
The potential of amoeba-based processes for natural product syntheses	42
Single-cell omics analysis with genome-scale metabolic modeling	42
Impact of anthropogenic contamination on glacier surface biota	42
Editorial overview: Pioneering innovations in food biotechnology	42
Understanding atmospheric intercontinental dispersal of harmful microorganisms	42
Editorial overview: Emerging routes to sustainable energy capture and conversion into value-added products	42
Pathway engineering for the biosynthesis of psychedelics	41
Metabolic and cellular engineering for the production of natural products	40
Synthetic apomixis: the beginning of a new era	40
Molecules to medicine: advances in metabolomics for natural product drug discovery	40
Editorial Board	39
Biochemical production with microbial bioelectrochemical systems	39
Editorial Board	39
Matchmaking at the cell surface using bispecifics to put cells on their best behavior	39
Editorial overview: Nanobiotechnology for immunoengineering	39

Complexity of subcellular metabolism: strategies for compartment-specific profiling	38
Understanding and harnessing the complexity of interspecies interactions in acetogenic mixotrophic co-cultures	38
Engineered methane biocatalysis: strategies to assimilate methane for chemical production	38
Synthetic mRNA – emerging new class of drug for tissue regeneration	37
The aging tumor metabolic microenvironment	37
Programmable synthetic biology tools for developing microbial cell factories	37
Potential use of microbial engineering in single-cell protein production	37
Operation at thermophilic temperatures: an underestimated asset for gas fermentation processes	37
What’s new in single-cell proteomics	37
Next-generation biological vector platforms for in vivo delivery of genome editing agents	36
Synthetic fuels: what are they and where do they come from?	36
Extracellular vesicles as therapeutics for inflammation and infection	36
Strategies and opportunities for engineering antifungal peptides for therapeutic applications	36
Antigen-specific nanomedicines for the treatment of autoimmune disease: target cell types, mechanisms and outcomes	35
Bridging the gender gap in autoimmunity with T-cell–targeted biomaterials	35
Targeting ripening regulators to develop fruit with high quality and extended shelf life	35
Machine learning for predicting phenotype from genotype and environment	34
De novo domestication: retrace the history of agriculture to design future crops	34
Editorial Board	34
Optimizing the value of bioinks and robotics to advance in vivo bioprinting	33
Strategies for uncovering stable isotope tracing patterns between cell populations	33
Engineering bacterial warriors: harnessing microbes to modulate animal physiology	33
Biotechnology approaches for natural product discovery, engineering, and production based on Burkholderia bacteria	33
Inhalable mRNA vaccines for respiratory diseases: a roadmap	33
Challenges and future perspectives for high-throughput chimeric antigen receptor T cell discovery	33
Can digital twin efforts shape microorganism-based alternative food?	32
Beyond vancomycin: recent advances in the modification, reengineering, production and discovery of improved glycopeptide antibiotics to tackle multidrug-resistant bacteria	32
Microbiological food safety considerations in shelf-life extension of fresh fruits and vegetables	32
Biohybrid approaches to interface with the nervous system: the best of both worlds	32
Editorial Board	32
Cell-free synthesis of industrial chemicals and biofuels from carbon feedstocks	31
Recent innovations in cannabinoid chemistry, biology, and biosynthesis	31
Analytical tools for unravelling the metabolism of gas-fermenting Clostridia	31
Editorial Board	30
An integrated eco-evolutionary framework to predict population-level responses of climate-sensitive pathogens	30
Senescent cells in tissue engineering	30
Editorial overview: Tissue, cell, and pathway engineering	30
Biologics-based degraders — an expanding toolkit for targeted-protein degradation	30
Corrigendum to “Unraveling the mechanobiology of immune cells” [Curr Opin Biotechnol 66 (2020) 236-245]	30
Achieving net zero CO2 emission in the biobased production of reduced platform chemicals using defined co-feeding of methanol	30
Clustered regularly interspaced short palindromic repeats tools for plant metabolic engineering: achievements and perspectives	30
Decoding dissolved information: environmental DNA sequencing at global scale to monitor a changing ocean	29
Engineering plant–microbe communication for plant nutrient use efficiency	29
Quantitative and analytical tools to analyze the spatiotemporal population dynamics of microbial consortia	29
Genetic and process engineering for polyhydroxyalkanoate production from pre- and post-consumer food waste	29
Advances in engineering substrate scope of Pseudomonas cell factories	29
In situ characterization of the tumor microenvironment	29
Advances in engineering and optimization of transcription factor-based biosensors for plug-and-play small molecule detection	29
Searching for the optimal microbial factory: high-throughput biosensors and analytical techniques for screening small molecules	28
Recent trends in the modification of polyphenolic compounds using hydroxylation and glycosylation	28
Division of labor for substrate utilization in natural and synthetic microbial communities	28
General framework for enzyme-photo-coupled catalytic system toward carbon dioxide conversion	28
Progress and challenges in the translation of cancer nanomedicines	28
Engineering next-generation chimeric antigen receptor-T cells: recent breakthroughs and remaining challenges in design and screening of novel chimeric antigen receptor variants	28
Two in one: the emerging concept of bifunctional antibodies	27
Sustainability in food-waste reduction biotechnology: a critical review	27
Mycotoxin risks are lower in biotech corn	27
Recent advances in microbial synthesis of polyphenols	26
Advances in engineering algae for biofuel production	26
Recent advances in microbial production of rare sugars and steviols	26
Computational models in systems biology: standards, dissemination, and best practices	26
Engineering bacteria for cancer immunotherapy	26
Integrating bioprinting and optogenetic technologies for precision plant tissue engineering	26
Carbon recycling with synthetic CO2 fixation pathways	26
Force in numbers: high-throughput screening approaches to unlock microbial transport	26
Pleiotropy, a feature or a bug? Toward co-ordinating plant growth, development, and environmental responses through engineering plant hormone signaling	25
Eubacterium limosum as a biocatalyst for sustainable methanol bioconversion	25
Understanding methanol metabolism through systems biology: advances and future perspectives	25
Machine learning applications to improve flavor and nutritional content of horticultural crops through breeding and genetics	25
Proteomics insights into the fungal-mediated bioremediation of environmental contaminants	25
Cytochromes P450 in the biocatalytic valorization of lignin	25
Biomolecular feedback controllers: from theory to applications	25
Path to zero emission of nitrous oxide in sewage treatment: is nitrification controllable or avoidable?	25
Combining enzyme and metabolic engineering for microbial supply of therapeutic phytochemicals	24
Approaches for a more microbiologically and chemically safe dried fruit supply chain	24
Engineering organoids as cerebral disease models	24
Cell-free enzyme cascades — application and transition from development to industrial implementation	24
Cellobiose dehydrogenase in biofuel cells	24
Building mutational bridges between carbohydrate-active enzymes	24
Getting better all the time — recent progress in the development of CRISPR/Cas-based tools for plant genome engineering	24

Quantifying nanoparticle delivery: challenges, tools, and advances	24
Drugging the microbiome and bacterial live biotherapeutic consortium production	23
Optogenetics in medicine: innovations and therapeutic applications	23
The double life of CRISPR–Cas13	23
Anaerobic microbial core for municipal wastewater treatment — the sustainable platform for resource recovery	23
Designed dietary fibers: engineering carbohydrate structure for precision modulation of the human gut microbiome	23
SgRNA engineering for improved genome editing and expanded functional assays	23
Engineering microbial consortia with rationally designed cellular interactions	23
Architectures of emerging biofoundry platforms for synthetic biology	23
Continuous biomanufacturing with microbes — upstream progresses and challenges	23
Industrial potential of the enzymatic synthesis of nucleoside analogs: existing challenges and perspectives	23
Window of sustainable bioprocess operation: towards merging environmental sustainability assessment and process operation at early-stage bioprocess development	22
Microalgal and bacterial auxin biosynthesis: implications for algal biotechnology	22
Machine learning in wastewater: opportunities and challenges — “not everything is a nail!”	22
Microbial production of chemicals driven by CRISPR-Cas systems	22
Technologies for the discovery of G protein–coupled receptor–targeting biologics	22
Recent advances in the biological depolymerization and upcycling of polyethylene terephthalate	22
Editorial overview: Phosphate Special Issue	22