OOIR: Observatory of International Research

Papers

(The H4-Index of Current Opinion in Biotechnology is 46. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Deep learning for optimization of protein expression	243
Virome studies of food production systems: time for ‘farm to fork’ analyses	191
Strategies for uncovering stable isotope tracing patterns between cell populations	154
Stop helping pathogens: engineering plant susceptibility genes for durable resistance	103
Recent progress in the synthesis of advanced biofuel and bioproducts	100
Beyond vancomycin: recent advances in the modification, reengineering, production and discovery of improved glycopeptide antibiotics to tackle multidrug-resistant bacteria	99
Assessing the potential to harness the microbiome through plant genetics	95
Biofabrication strategies for cardiac tissue engineering	90
Recent advances in bivalve-microbiota interactions for disease prevention in aquaculture	90
The limitless applications of single-cell metabolomics	90
Avoidance of detrimental defense responses in beneficial plant–microbe interactions	83
Editorial overview: Biotechnology to help understand and harness biotic interactions in plants	82
Novel transducers for high-channel-count neuroelectronic recording interfaces	80
Bioelectrosynthesis systems	79
Editorial Board	76
Editorial Board	73
Editorial overview: Tissue, cell, and pathway engineering: Recent innovations in biomedical technologies	72
Autophagy as a critical driver of metabolic adaptation, therapeutic resistance, and immune evasion of cancer	71
Tumor lipid metabolism: a mechanistic link between diet and cancer progression	69
Pathway elucidation and engineering of plant-derived diterpenoids	68
Recent advances of machine learning applications in human gut microbiota study: from observational analysis toward causal inference and clinical intervention	66
Constructing next-generation CRISPR–Cas tools from structural blueprints	66
Editorial Board	65
Editorial overview: Analytical biotechnology for healthcare, strain engineering, biosensing and synthetic biology	65
Biohybrid approaches to interface with the nervous system: the best of both worlds	65

Systems biology-based analysis of cell-free systems	65
Recent advances in microbial community analysis from machine learning of multiparametric flow cytometry data	64
The dawn of interoperating spatial models in cell biology	63
High-Throughput Functional Genomics for Energy Production	60
Editorial Board	60
Engineering healthy crops: molecular strategies for enhancing the plant immune system	60
Inhalable mRNA vaccines for respiratory diseases: a roadmap	60
Role of biotechnology in the advancement of biodegradable polymers and functionalized additives for food packaging systems	58
Stem cells characterization: OMICS reinforcing analytics	56
Microenvironmental effects can masquerade as substrate channelling in cascade biocatalysis	56
Progress toward rapid, at-line N-glycosylation detection and control for recombinant protein expression	56
Engineering protein nanoparticles for drug delivery	54
Biotechnological interventions in reducing losses of tropical fruits and vegetables	54
Bridging the gender gap in autoimmunity with T-cell–targeted biomaterials	53
Isotope tracing in health and disease	52
Adaptive biomimicry: design of neural interfaces with enhanced biointegration	51
How much could improving photosynthesis increase crop yields? A call for systems-level perspectives to guide engineering strategies	49
The journey of a lifetime — development of Pfizer’s COVID-19 vaccine	48
Jump-starting chimeric antigen receptor-T cells to go the extra mile with nanotechnology	47
The yin and yang of itaconate metabolism and its impact on the tumor microenvironment	46
De novo domestication: retrace the history of agriculture to design future crops	46
Bioengineering applications for hearing restoration: emerging biologically inspired and biointegrated designs	46