Experimental Physiology

Article	Citations
Chasing genes at high‐altitude	195
Physiological assessment of a 16 day, 4385 km ultra‐endurance mountain bike race: A case study	104
To Mars through LEO: How commercial space travel will change exploration‐enabling research	84
Dietary manipulations for health and the prevention and management of disease: An editorial	64
Mechanosensory encoding in ex vivo muscle–nerve preparations	43
No difference in mean middle cerebral artery blood velocity responses between lower‐ and upper‐body unilateral resistance exercise in untrained individuals	42
	40
Low‐load resistance exercise with and without blood flow restriction: Which is more effective for increasing local muscle endurance and why?	38
When is the right time to initiate rehabilitation? Time will tell…	33
Myths and methodologies: Considerations for evaluating the time course of thermoregulatory adaptation during heat acclimation	32
Beyond single stressors/stimuli in adaptive physiology: Dose–response relationships and translational challenges	29
Using environmental and exercise physiology to address gender inequalities in climate change and occupational health research	26
Moderate maternal nutrient restriction alters type II alveolar epithelial cell density in the non‐human primate fetal lung	26
Blunted hypoxic pulmonary vasoconstriction in apnoea divers	25
Interference with glutamate antiporter system xc− enables post‐hypoxic long‐term potentiation in hippocampus	23
ZFP36 inhibits the pro‐apoptotic effects of transforming growth factor β1 on mitral valve interstitial cells via the GTP‐binding protein 6 pathway in mitral valve prolapse	22
Nitrite supplementation alleviates cerebrovascular dysfunction in chronically stressed mice, but cognitive decline remains	22
Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle	21
Larger reductions in blood pressure during post‐exercise standing, but not middle cerebral artery blood velocity, in resistance‐trained versus untrained individuals	21
Thermo‐haemodynamic coupling during regional thigh heating: Insight into the importance of local thermosensitive mechanisms in blood circulation	20
Chitinase 3‐like 1 overexpression aggravates hypoxia–reoxygenation injury in IEC‐6 cells by inhibiting the PI3K/AKT signalling pathway	20
Applying thermal therapy: Comparison of different commercially available heating devices to increase muscle temperature	20
Thermal and cardiovascular responses to sauna are attenuated by adding cold water immersion to cooling breaks	19
How do physiological networks respond to normobaric hypoxia and isometric exercise?	19
The physiology of survival: Fluid and food	19

The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis	19
Acute heat stress amplifies exercise‐induced metabolomic perturbations and reveals variation in circulating amino acids in endurance‐trained males	18
Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut–athlete on Mars exploration missions	18
Acute partial sleep restriction does not impact arterial function in young and healthy humans	17
Network model of skeletal muscle cell signalling predicts differential responses to endurance and resistance exercise training	17
Issue Information	16
Central command suppresses pressor‐evoked bradycardia at the onset of voluntary standing up in conscious cats	16
Issue Information	16
Issue Information	16
Muscle fibre size and myonuclear positioning in trained and aged humans	16
Comparison of exercise training and repeated hot water immersion on vascular function in overweight older adults	16
Unlocking the complications of chronic concussion in rugby players: A traumatic tale of cerebral injury	15
Mapping the variability of in vivo rat uterine electrical properties throughout the oestrous cycle	15
Effect of adrenaline on serum mid‐regional pro‐atrial natriuretic peptide and central blood volume	15
Even periconceptional alcohol consumption can have long‐term consequences on heart health in the offspring	15
Passive thigh heating improves peak force production in younger adults and early isokinetic force production in younger and older adults	15
Marie Krogh's contributions to the study of thyroid physiology and pathophysiology	15
Habitual exercise in youth: A ʻbrainyʼ idea	15
Kidney function and cognitive impairment	15
Issue Information	15
On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur	14
Impact of heat exposure during immobilization‐induced de‐training and re‐training on aerobic capacity and haemoglobin mass	14
Effect of exercise on chronic neck pain and central sensitization: A protocol for a randomized crossover trial	14
From fatigue to physiology: Submaximal 2‐day cardiopulmonary exercise test and emerging standards in long COVID	14
The physiology of survival: Breath‐hold shallow‐water diving	14
Alveolar deadspace and intrapulmonary shunt in healthy individuals and in individuals who have recovered from COVID‐19 infection	14
Dynamic cerebral autoregulation quantification with spontaneous arterial blood pressure oscillations: Is transfer function analysis our best option?	14
Limited matching of the cardiac output response to the peripheral demand of heat stress and exercise	14
Acute cardiovascular responses to slow and deep breathing in normotensive men and women	14
Issue Information	14
Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury	14
Comparing 17β‐estradiol and progesterone concentrations in young, physically active females: Insights from plasma versus serum analysis	13
Reply to letter to the editor in response to: “Carbon monoxide to ‘simulate altitude’”	13
Alpha band oscillations in common synaptic input are explanatory of the complexity of isometric knee extensor muscle torque signals	13
Delineating the impacts of air temperature and humidity for endurance exercise	13
CTRP6‐mediated cardiac protection in heart failure via the AMPK/SIRT1/PGC‐1α signalling pathway	13
Exertional heat stress and intestinal barrier injury: Does chronic disease add fuel to the fire?	13
From SilverStar to shining stars: Physiology's next generation	13
Traumatic arteriovenous fistula after ice axe injury 27 years ago: A case report	13
Diverse perspectives on respiratory chemoreceptor interactions: Resuscitating an expired debate	13
Post‐exercise hot or cold water immersion does not alter perception of effort or neuroendocrine responses during subsequent moderate‐intensity exercise	13
Handgrip exercise does not alter CO2‐mediated cerebrovascular flow‐mediated dilation	13
Is polycystic ovary syndrome associated with elevated muscle sympathetic nerve activity?	13
Therapeutic intervention with sinomenine and irisin to preserve cardiac function after ischaemia–reperfusion injury	13
Issue Information	13
On changes, challenges and collaboration: Introducing a new Editor‐in‐Chief and moving to Open Access	12
Skeletal muscle mitochondrial marker responses to a single bout and 6 weeks of high load versus high volume resistance training in previously trained men	12
Skin wound healing as a mirror to cardiac wound healing	12
Insulin‐like growth factor‐1 infusion in preterm piglets does not affect growth parameters of skeletal muscle or tendon tissue	12
News, views and where best to choose	12

The contribution of the tendon electrode to M‐wave characteristics in the biceps brachii, vastus lateralis and tibialis anterior	12
Cardiorespiratory consequences of obesity: a tale of two pumps	12
A comparison of normobaric and hypobaric hypoxia effects on cerebrovascular response pre and post maximal exercise	12
Exercise‐induced pain within endurance exercise settings: Definitions, measurement, mechanisms and potential interventions	12
The role of orexin A in the pathogenesis of ischaemic stroke at high altitude	12
	12
Characterization of differences in immune responses during bolus and continuous infusion endotoxin challenges using mathematical modelling	12
Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest	12
Challenging dynamic cerebral autoregulation across the physiological CO2 spectrum: Influence of biological sex and cardiac cycle	11
Bioenergetic profiles and respiratory control in mitochondrial physiology: Precision analysis of oxidative phosphorylation	11
Peripheral nerve‐derived fibroblasts promote neurite outgrowth in adult dorsal root ganglion neurons more effectively than skin‐derived fibroblasts	11
The impact of long‐haul travel and 13 h time change on sleep and rest activity circadian rhythm in speed skaters during World Cup competitions	11
Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes	11
GABA B receptor‐mediated modulation of sensory neuron excitability: Roles of Ca V 2.2, G‐protein‐c	11
Response to the letter from Bushfield and Day: Potential pitfalls of using a correction to normative values in the assessment of acid–base compensation during early ascent to high altitude	11
The severity of acute hypoxaemia determines distinct changes in intracortical and spinal neural circuits	11
DYNamic Assessment of Multi‐Organ level dysfunction in patients recovering from COVID‐19: DYNAMO COVID‐19	11
Contemporary concepts in ‘exercise as medicine’ and related fields	11
Effects of bed rest and immobilization on intramuscular and intermuscular adipose tissue: A systematic review	11
‘One for all, all for one’: A tale from the formative years of Scandinavian exercise physiology	11
Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation	11
Optimizing cerebrovascular endothelial health through shear stress modulation	10
Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA	10
Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression	10
Issue Information	10
Impaired glucose tolerance and insulin resistance in a prenatally‐androgenized rat model of polycystic ovary syndrome in later life	10
The impact of type 2 diabetes on tendon material properties and locomotor function in the db / db mouse	10
Effect of moderate altitude and nocturnal oxygen therapy on cerebrovascular function in patients with COPD: A randomized, crossover trial at 2048 m	10
Acute alterations in blood lactate in the setting of transient stress induced myocardial ischaemia	10
	10
Defying gravity: Breath, beat and brain	10
A single breath of nitric oxide does not alter pulmonary perfusion pressure	10
RETRACTED: Corrigendum	10
Accuracy of next‐generation wireless skin temperature sensors during exercise–heat stress	10
The maturation of regional sweating patterns from childhood to young adulthood in females	9
From mechanistic promise to clinical translation: Passive heat therapy as a cardiovascular and functional adjunct in ageing and disease	9
A new method for non‐invasive determination of effective pulmonary blood flow and cardiac output in spontaneously breathing subjects	9
Inhibitory effect of oestradiol on the cardiac K V 7.1/KCNE1 channel is species dependent	9
Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism	9
Cerebral haemodynamic responses to inspiratory muscle work	9
Vascular limitations in blood pressure regulation with age in women: Insights from exercise and acute cardioselective β‐blockade	9
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury	9
The principles of systems biology	9
Caffeine in cerebrovascular research: To withdraw or not to withdraw?	9
The acute effects of dynamic stretching on the neuromuscular system are independent of the velocity	9
Functional assays reflective of cancer hallmarks in BT‐549 cells are not impacted by media supplemented with exercise‐trained plasma	9
Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole‐body passive hyperthermia in healthy humans	9
Distinct adaptations of muscle endurance but not strength or hypertrophy to low‐load resistance training with and without blood flow restriction	9
Issue Information	9
Issue Information	9
Temporal summation in human peripheral axons when stimulated transcutaneously with a 10‐kHz waveform	9
Gut microbiota in regulation of childhood bone growth	9
Maximal strength and voluntary activation of adductor pollicis after a single session of acute intermittent hypercapnia or acute intermittent hypoxia	9
GST polymorphism as a predictive biomarker for modulating the susceptibility to chronic obstructive pulmonary disease: A North Indian study	9
Prespecified analysis plans are not suitable for exploratory experimental physiology research	9
Changes in motor unit behaviour across repeated bouts of eccentric exercise	9
Effect of internal and external cooling on high‐intensity intermittent cycling performance and cognitive function in the heat	9
Pulmonary vascular reactivity to supplemental oxygen in Sherpa and lowlanders during gradual ascent to high altitude	9
Oral ketone monoester supplementation does not accelerate recovery of muscle force or modulate circulating cytokine concentrations after muscle‐damaging eccentric exercise in healthy males and females	9
Potential pitfalls of using a correction to normative values for the assessment of acid–base compensation during early ascent to high altitude	8
Issue Information	8
Spectral changes in skin blood flow during pressure manipulations or sympathetic stimulation	8
Lower vascular conductance responses to handgrip exercise are improved following acute antioxidant supplementation in young individuals with post‐traumatic stress disorder	8
Passive hyperthermia increases blood circulation in specific regions, largely independent of conduit artery mechanics and cardiac performance	8
Issue Information	8
Spontaneous Ca 2+ signals in the developing mammalian cochlea of live mice under different anaesthetic regimes	8
Computing muscle mechanical state variables from combined proprioceptive sensory feedback	8
Energy expenditure, intake and availability in female soccer players via doubly labelled water: Are we misrepresenting low energy availability?	8
ZDF (fa/fa) rats show increasing heterogeneity in main parameters during ageing, as confirmed by biometrics, oxidative stress markers and MMP activity	8
Computational study of the excitation of human induced pluripotent stem cell‐derived cardiomyocytes	8
Changes in cerebral autoregulation and vasoreactivity after surgical aortic valve replacement: a prospective study	8
Acute high‐intensity muscle contraction moderates AChR gene expression independent of rapamycin‐sensitive mTORC1 pathway in rat skeletal muscle	8
Integrative regulation of cerebral blood flow in response to exercise and environmental extremes	8
The effect of protein or amino acid provision on immobilization‐induced muscle atrophy in healthy adults: A systematic review and meta‐analysis	8
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials	8
Use of transcutaneous spinal cord stimulation to explore inhibitory and facilitatory circuits in muscles of the human lower limb	8
Alterations to longitudinal muscle morphology and mechanical function following immobilization and recovery in female ovariectomized and intact rats	8
Issue Information	8
Neuromuscular fatigue and loss of torque complexity during severe‐intensity exercise: The role of muscle size	8
Cerebral oxygenation and skeletal muscle responses to time trial, maximal oxygen uptake and time to exhaustion exercise	8

Applying lessons from limb muscle disuse and ageing to better understand ventilator‐induced diaphragm dysfunction	8
Effect of high‐fat diet on isometric, concentric and eccentric contractile performance of skeletal muscle isolated from female CD‐1 mice	8
Knee movements cause changes in the firing behaviour of muscle spindles located within the mono‐articular ankle extensor soleus in the rat	8
Modulation of cerebral blood flow and cognition by hyperthermia and hypoxia: An electroencephalographic event‐related potentials perspective	8
Heat and carbon monoxide exposure: Is two better than one?	8
	8
Memory impairment in the D2.mdx mouse model of Duchenne muscular dystrophy is prevented by the adiponectin receptor agonist ALY688	8
Passive heat intervention research in women: Systematic review and audit of female representation	8
The sympathetic nervous system in healthy and hypertensive pregnancies: physiology or pathology?	7
Cell‐free DNA kinetics in response to muscle‐damaging exercise: A drop jump study	7
The effect of exercise in a fasted state on plasma low‐density lipoprotein cholesterol concentrations in males and females	7
Pulmonary diffusing capacity to nitric oxide and carbon monoxide during exercise and in the supine position: a test–retest reliability study	7
Lower limb hyperthermia augments functional hyperaemia during small muscle mass exercise similarly in trained elderly and young humans	7
NEX4EX – A novel exercise device enabling resistive, plyometric and sensorimotor training during deep‐space missions: A case report	7
Why is the muscle spindle so complicated?	7
Exercise oximetry in clinical practice: A single‐centre perspective on procedure and techniques	7
Submaximal 2‐day cardiopulmonary exercise testing to assess exercise capacity and post‐exertional symptom exacerbation in people with long COVID	7
Control of blood pressure in the cold: differentiation of skin and skeletal muscle vascular resistance	7
Passive heat therapy is feasible but does not affect cardiometabolic health outcomes in persons with spinal cord injury – a pilot study	7
Individual assessment of ventilatory acclimatization at high altitude	7
Exercise‐induced effects on atherogenesis and tryptophan catabolism via the kynurenine pathway in an HIV‐associated atherosclerosis mouse model	7
Small muscle mass aerobic exercise in health and disease: Unique insights into muscle vascular and metabolic control and performance	7
The renal vasodilatation from β‐adrenergic activation in vivo in rats is not driven by KV7 and BKCa channels	7
The effect of artificial gravity on the outcome of a two‐week resistance vibration exercise programme: BRAVE study	7
Synbiotic supplementation ameliorates anxiety and myocardial ischaemia–reperfusion injury in hyperglycaemic rats by modulating gut microbiota	7
Acute intermittent hypoxia in neonatal rodent central nervous system facilitates respiratory frequency through the recruitment of hypothalamic areas	7
Cardiopulmonary function in special operations forces compared to conventional infantry soldiers	7
Stabilising function of the human diaphragm in response to involuntary augmented breaths induced with or without lower‐limb movements	7
Haemodynamic responses to small muscle mass exercise before and after lung transplantation in end‐stage chronic obstructive pulmonary disease	7
Galectin‐3 and suppression of tumorigenicity 2: Two emerging cardiac biomarkers that may be predictors of cardiac fibrosis development in sport	7
Impact of a 12‐week high‐intensity interval training intervention on cardiac structure and function after COVID‐19 at 12‐month follow‐up	7
Beyond the horizon: Why space biology is the next great innovation opportunity	7
	7
Using modified Fenn diagrams to assess ventilatory acclimatization during ascent to high altitude: Effect of acetazolamide	7
The importance of high‐quality heat adaptation research in females	7
Myths and methodologies: Assessing glycaemic control and associated regulatory mechanisms in human physiology research	7
Climate change, healthy ageing and the health crisis: is wisdom the link?	7
The effect of female breast surface area on skin stiffness and tactile sensitivity at rest and following exercise in the heat	7
From discovery to innovation in physiological research	7
Issue Information	7
The differential sensitivity of the hypothalamic–hypophysial–ovarian axis to 5‐hydroxytryptophan alters the secretion of estradiol	7
Breath‐by‐breath measurement of alveolar gas exchange must preserve mass balance and conform to a physiological definition of a breath	7
	6
Preserved force control by the digits via minimal sparing of cortico‐spinal connectivity after stroke	6
Chronic intermittent hypoxia‐mediated cognitive dysfunction in ovariectomized rats	6
Durability as an index of endurance exercise performance: Methodological considerations	6
Ultrasound predicts skeletal muscle fat infiltration in healthy middle‐aged and young adults: Validation against MRI	6
Galectin‐3 plasma levels are associated with left atrial contractile function in long‐distance runners	6
Early life stress and hormonal status influence orexin‐1 receptor expression in structures regulating cardiorespiratory responses to CO2	6
Race and ethnicity in physiological research: When socio‐political constructs and biology collide	6
Neural control of coronary artery blood flow by non‐adrenergic and non‐cholinergic mechanisms	6
Acute and long‐term effect of specific and non‐specific exercises in patients with chronic neck pain: A protocol for a randomized controlled trial	6
Respiratory muscle metaboreflex: Connecting the ‘dots’	6
On the mechanism of control of the pulse rate	6
Making sense of the carotid body counter‐regulatory response to hypoglycaemia	6
Daily hot‐water immersion preserves altitude‐induced haemoglobin mass expansion following descent independent of erythropoietin	6
Is the blood pressure response to exercise associated with the motor unit firing patterns of the exercised muscle?	6
Physiology of lived experience: Boston wrong: A series of physiological calamities at the Boston Marathon	6
One minute of light‐intensity stair‐stepping decreases postprandial glycaemia in the evening in non‐diabetic adults: A randomized controlled trial	6
Klotho, the Greek goddess controlling the fate of skeletal muscle satellite cells	6
A comparison of the neuromuscular, cardiopulmonary and muscle oxygenation responses to single‐ and double‐leg cycling in older adults	6
Reply to Veerkamp et al.: Comments on Harkness‐Armstrong et al. (2021)	6
Unpacking the multimodal, multi‐scale data of the fast and slow lanes of the cardiac vagus through computational modelling	6
Blood flow restriction training attenuates changes in local muscle endurance: At odds with previous work?	6
Effects of a high‐sugar mixed meal on cerebrovascular haemodynamics in young, healthy versus middle‐aged adults with cardiometabolic risk factors	6
From hot tub to high altitude: The makings of a human physiology field expedition and the next generation of physiologists	6
A new method for bedside determination of effective lung volume and functional residual capacity	6
Locomotor muscle dysfunction and rehabilitative exercise training in fibrotic interstitial lung disease: Where are we at and where could we go?	6
A change to Experimental Physiology’s statistics policy	6
Effects of hyperprotein diet on anxiety, haemodynamics and morphofunctional aspects of the heart of Wistar rats	6
Advancing tele‐physiology: A chest patch solution for continuous, non‐invasive remote monitoring in a hypoxic environment	6
Measuring pulmonary oxygen uptake kinetics: Contemporary perspectives	6
Death by nitrogen anoxia: On the integrated physiology of human execution	6
Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults	6
Neuroprotective effects of sinomenine and metformin in diabetic stroke: Role of NLRP3/caspase‐1 and mitophagy	6
Effects of 14 days of head‐down bed rest with or without exercise, and subsequent recovery on bone turnover, density and structure in older adults	6
Skin wetness perception across body sites in children and adolescents aged 7–16 years old	6
Digital N ‐of‐1 trials and their application in experimental physiology	6
Issue Information	6
Acute effects of insulin and insulin‐induced hypoglycaemia on carotid body chemoreceptor activity and cardiorespiratory responses in dogs	6
	6
Glycosylation of the murine cardiac channel TRPM4 is altered by the pathogenic p.I376T variant	6
Artificial intelligence driven clustering of blood pressure profiles reveals frailty in orthostatic hypertension	6
Blood flow restriction exercise during microgravity exposure in parabolic flight	6
Ketone monoester attenuates oxygen desaturation during weighted ruck exercise under acute hypoxic exposure but does not impact cognitive performance	6
Cerebral blood flow regulation, central arterial stiffness and traumatic brain injury: Effects of aerobic exercise training	6
Biophysical, thermo‐physiological and perceptual determinants of cool‐seeking behaviour during exercise in younger and older women	6
	6
Bridging brain, respiratory, and locomotor muscle: Integrated view of between‐sex differences during exercise	6
TRPV1 blockade restores the baroreflex control of renal sympathetic nerve activity in cisplatin‐induced renal injury in rats	6
	6
Water and wisdom: Hydration as a defence against dementia	6
Diffusion and physical constraints limit oxidative capacity, capillary supply and size of muscle fibres in mice and humans	6
Letter about the recently published Viewpoint by H. B. Rossiter and D. C. Poole	6
Cardiovascular and respiratory evaluation in adenosine A2A receptor knockout mice submitted to short‐term sustained hypoxia	6