Experimental Physiology

Article	Citations
Chasing genes at high‐altitude	183
Physiological assessment of a 16 day, 4385 km ultra‐endurance mountain bike race: A case study	97
No difference in mean middle cerebral artery blood velocity responses between lower‐ and upper‐body unilateral resistance exercise in untrained individuals	78
Larger reductions in blood pressure during post‐exercise standing, but not middle cerebral artery blood velocity, in resistance‐trained versus untrained individuals	76
Using environmental and exercise physiology to address gender inequalities in climate change and occupational health research	61
How do physiological networks respond to normobaric hypoxia and isometric exercise?	51
The physiology of survival: Fluid and food	43
Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut–athlete on Mars exploration missions	37
To Mars through LEO: How commercial space travel will change exploration‐enabling research	37
The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis	34
Dietary manipulations for health and the prevention and management of disease: An editorial	32
The miRNA‐143‐3p–Sox6–Myh7 pathway is altered in obesogenic diet‐induced cardiac hypertrophy	30
Mechanosensory encoding in ex vivo muscle–nerve preparations	30
When is the right time to initiate rehabilitation? Time will tell…	28
Moderate maternal nutrient restriction alters type II alveolar epithelial cell density in the non‐human primate fetal lung	26
Beyond single stressors/stimuli in adaptive physiology: Dose–response relationships and translational challenges	24
	23
Acute partial sleep restriction does not impact arterial function in young and healthy humans	22
Low‐load resistance exercise with and without blood flow restriction: Which is more effective for increasing local muscle endurance and why?	22
Blunted hypoxic pulmonary vasoconstriction in apnoea divers	21
Applying thermal therapy: Comparison of different commercially available heating devices to increase muscle temperature	21
Acute heat stress amplifies exercise‐induced metabolomic perturbations and reveals variation in circulating amino acids in endurance‐trained males	20
Chitinase 3‐like 1 overexpression aggravates hypoxia–reoxygenation injury in IEC‐6 cells by inhibiting the PI3K/AKT signalling pathway	20
Myths and methodologies: Considerations for evaluating the time course of thermoregulatory adaptation during heat acclimation	19
Network model of skeletal muscle cell signalling predicts differential responses to endurance and resistance exercise training	19

Muscle fibre size and myonuclear positioning in trained and aged humans	19
Nitrite supplementation alleviates cerebrovascular dysfunction in chronically stressed mice, but cognitive decline remains	18
Interference with glutamate antiporter system xc− enables post‐hypoxic long‐term potentiation in hippocampus	18
Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle	18
Thermo‐haemodynamic coupling during regional thigh heating: Insight into the importance of local thermosensitive mechanisms in blood circulation	18
Issue Information	17
ZFP36 inhibits the pro‐apoptotic effects of transforming growth factor β1 on mitral valve interstitial cells via the GTP‐binding protein 6 pathway in mitral valve prolapse	17
Issue Information	16
The effect of acute intradermal administration of ascorbate on heat loss responses in older adults with uncomplicated controlled hypertension	16
Central command suppresses pressor‐evoked bradycardia at the onset of voluntary standing up in conscious cats	16
Issue Information	16
Kidney function and cognitive impairment	16
Alpha band oscillations in common synaptic input are explanatory of the complexity of isometric knee extensor muscle torque signals	16
Unlocking the complications of chronic concussion in rugby players: A traumatic tale of cerebral injury	16
Habitual exercise in youth: A ʻbrainyʼ idea	15
Even periconceptional alcohol consumption can have long‐term consequences on heart health in the offspring	14
Issue Information	14
The physiology of survival: Breath‐hold shallow‐water diving	14
Mapping the variability of in vivo rat uterine electrical properties throughout the oestrous cycle	14
Handgrip exercise does not alter CO2‐mediated cerebrovascular flow‐mediated dilation	14
Acute cardiovascular responses to slow and deep breathing in normotensive men and women	14
Marie Krogh's contributions to the study of thyroid physiology and pathophysiology	14
Post‐exercise hot or cold water immersion does not alter perception of effort or neuroendocrine responses during subsequent moderate‐intensity exercise	14
Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury	13
On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur	13
Alveolar deadspace and intrapulmonary shunt in healthy individuals and in individuals who have recovered from COVID‐19 infection	13
Dynamic cerebral autoregulation quantification with spontaneous arterial blood pressure oscillations: Is transfer function analysis our best option?	13
From SilverStar to shining stars: Physiology's next generation	13
Exertional heat stress and intestinal barrier injury: Does chronic disease add fuel to the fire?	13
Issue Information	13
Delineating the impacts of air temperature and humidity for endurance exercise	13
Passive thigh heating improves peak force production in younger adults and early isokinetic force production in younger and older adults	13
Is polycystic ovary syndrome associated with elevated muscle sympathetic nerve activity?	13
Impact of heat exposure during immobilization‐induced de‐training and re‐training on aerobic capacity and haemoglobin mass	13
Effect of exercise on chronic neck pain and central sensitization: A protocol for a randomized crossover trial	13
Comparing 17β‐estradiol and progesterone concentrations in young, physically active females: Insights from plasma versus serum analysis	12
Diverse perspectives on respiratory chemoreceptor interactions: Resuscitating an expired debate	12
From fatigue to physiology: Submaximal 2‐day cardiopulmonary exercise test and emerging standards in long COVID	12
Limited matching of the cardiac output response to the peripheral demand of heat stress and exercise	12
Issue Information	12
Effect of adrenaline on serum mid‐regional pro‐atrial natriuretic peptide and central blood volume	12
Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes	12
On changes, challenges and collaboration: Introducing a new Editor‐in‐Chief and moving to Open Access	11
Short‐term effects of electronic cigarettes on cerebrovascular function: A time course study	11
	11
Characterization of differences in immune responses during bolus and continuous infusion endotoxin challenges using mathematical modelling	11
Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest	11
Cardiorespiratory consequences of obesity: a tale of two pumps	11
News, views and where best to choose	11
Challenging dynamic cerebral autoregulation across the physiological CO2 spectrum: Influence of biological sex and cardiac cycle	11

DYNamic Assessment of Multi‐Organ level dysfunction in patients recovering from COVID‐19: DYNAMO COVID‐19	11
Insulin‐like growth factor‐1 infusion in preterm piglets does not affect growth parameters of skeletal muscle or tendon tissue	11
Skeletal muscle mitochondrial marker responses to a single bout and 6 weeks of high load versus high volume resistance training in previously trained men	11
Skin wound healing as a mirror to cardiac wound healing	11
The role of orexin A in the pathogenesis of ischaemic stroke at high altitude	11
The contribution of the tendon electrode to M‐wave characteristics in the biceps brachii, vastus lateralis and tibialis anterior	11
Peripheral nerve‐derived fibroblasts promote neurite outgrowth in adult dorsal root ganglion neurons more effectively than skin‐derived fibroblasts	11
A comparison of normobaric and hypobaric hypoxia effects on cerebrovascular response pre and post maximal exercise	11
Contemporary concepts in ‘exercise as medicine’ and related fields	11
Response to the letter from Bushfield and Day: Potential pitfalls of using a correction to normative values in the assessment of acid–base compensation during early ascent to high altitude	10
GABA B receptor‐mediated modulation of sensory neuron excitability: Roles of Ca V 2.2, G‐protein‐c	10
The impact of long‐haul travel and 13 h time change on sleep and rest activity circadian rhythm in speed skaters during World Cup competitions	10
CTRP6‐mediated cardiac protection in heart failure via the AMPK/SIRT1/PGC‐1α signalling pathway	10
‘One for all, all for one’: A tale from the formative years of Scandinavian exercise physiology	10
Effects of bed rest and immobilization on intramuscular and intermuscular adipose tissue: A systematic review	10
Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation	10
Exercise‐induced pain within endurance exercise settings: Definitions, measurement, mechanisms and potential interventions	10
The severity of acute hypoxaemia determines distinct changes in intracortical and spinal neural circuits	10
Bioenergetic profiles and respiratory control in mitochondrial physiology: Precision analysis of oxidative phosphorylation	10
The acute effect of a laboratory shame induction protocol on endothelial function in young, healthy adults	9
The impact of type 2 diabetes on tendon material properties and locomotor function in the db / db mouse	9
Issue Information	9
	9
Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism	9
Changes in motor unit behaviour across repeated bouts of eccentric exercise	9
Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole‐body passive hyperthermia in healthy humans	9
Functional assays reflective of cancer hallmarks in BT‐549 cells are not impacted by media supplemented with exercise‐trained plasma	9
RETRACTED: Corrigendum	9
Impaired glucose tolerance and insulin resistance in a prenatally‐androgenized rat model of polycystic ovary syndrome in later life	9
A single breath of nitric oxide does not alter pulmonary perfusion pressure	9
Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA	9
Effect of moderate altitude and nocturnal oxygen therapy on cerebrovascular function in patients with COPD: A randomized, crossover trial at 2048 m	9
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury	9
Oral ketone monoester supplementation does not accelerate recovery of muscle force or modulate circulating cytokine concentrations after muscle‐damaging eccentric exercise in healthy males and females	9
Acute alterations in blood lactate in the setting of transient stress induced myocardial ischaemia	9
Inhibitory effect of oestradiol on the cardiac K V 7.1/KCNE1 channel is species dependent	9
Optimizing cerebrovascular endothelial health through shear stress modulation	9
Defying gravity: Breath, beat and brain	9
Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression	9
Pulmonary vascular reactivity to supplemental oxygen in Sherpa and lowlanders during gradual ascent to high altitude	9
GST polymorphism as a predictive biomarker for modulating the susceptibility to chronic obstructive pulmonary disease: A North Indian study	9
Changes in cerebral autoregulation and vasoreactivity after surgical aortic valve replacement: a prospective study	8
Spectral changes in skin blood flow during pressure manipulations or sympathetic stimulation	8
Effect of high‐fat diet on isometric, concentric and eccentric contractile performance of skeletal muscle isolated from female CD‐1 mice	8
The effect of protein or amino acid provision on immobilization‐induced muscle atrophy in healthy adults: A systematic review and meta‐analysis	8
Distinct adaptations of muscle endurance but not strength or hypertrophy to low‐load resistance training with and without blood flow restriction	8
Vascular limitations in blood pressure regulation with age in women: Insights from exercise and acute cardioselective β‐blockade	8
From mechanistic promise to clinical translation: Passive heat therapy as a cardiovascular and functional adjunct in ageing and disease	8
The acute effects of dynamic stretching on the neuromuscular system are independent of the velocity	8
Issue Information	8
Maximal strength and voluntary activation of adductor pollicis after a single session of acute intermittent hypercapnia or acute intermittent hypoxia	8
Issue Information	8
Neuromuscular fatigue and loss of torque complexity during severe‐intensity exercise: The role of muscle size	8
Applying lessons from limb muscle disuse and ageing to better understand ventilator‐induced diaphragm dysfunction	8
Issue Information	8
Biomarkers of heatstroke‐induced organ injury and repair	8
Effect of internal and external cooling on high‐intensity intermittent cycling performance and cognitive function in the heat	8
Gut microbiota in regulation of childhood bone growth	8
Temporal summation in human peripheral axons when stimulated transcutaneously with a 10‐kHz waveform	8
Prespecified analysis plans are not suitable for exploratory experimental physiology research	8
The principles of systems biology	8
Modulation of cerebral blood flow and cognition by hyperthermia and hypoxia: An electroencephalographic event‐related potentials perspective	8
Heat and carbon monoxide exposure: Is two better than one?	8
ZDF (fa/fa) rats show increasing heterogeneity in main parameters during ageing, as confirmed by biometrics, oxidative stress markers and MMP activity	8
Sex differences in the ventilatory responses to exercise in mild to moderate obesity	8
Passive hyperthermia increases blood circulation in specific regions, largely independent of conduit artery mechanics and cardiac performance	8
Issue Information	8
Caffeine in cerebrovascular research: To withdraw or not to withdraw?	8
The maturation of regional sweating patterns from childhood to young adulthood in females	8
A new method for non‐invasive determination of effective pulmonary blood flow and cardiac output in spontaneously breathing subjects	8
Cerebral haemodynamic responses to inspiratory muscle work	8
Knee movements cause changes in the firing behaviour of muscle spindles located within the mono‐articular ankle extensor soleus in the rat	8
Impact of a 12‐week high‐intensity interval training intervention on cardiac structure and function after COVID‐19 at 12‐month follow‐up	7
Pulmonary diffusing capacity to nitric oxide and carbon monoxide during exercise and in the supine position: a test–retest reliability study	7
The effect of exercise in a fasted state on plasma low‐density lipoprotein cholesterol concentrations in males and females	7
Sarcoplasmic reticulum calcium handling in unbranched, immediately post‐necrotic fast‐twitch mdx fibres is similar to wild‐type littermates	7
Acute intermittent hypoxia in neonatal rodent central nervous system facilitates respiratory frequency through the recruitment of hypothalamic areas	7
Lower vascular conductance responses to handgrip exercise are improved following acute antioxidant supplementation in young individuals with post‐traumatic stress disorder	7
Acute high‐intensity muscle contraction moderates AChR gene expression independent of rapamycin‐sensitive mTORC1 pathway in rat skeletal muscle	7
Memory impairment in the D2.mdx mouse model of Duchenne muscular dystrophy is prevented by the adiponectin receptor agonist ALY688	7

Potential pitfalls of using a correction to normative values for the assessment of acid–base compensation during early ascent to high altitude	7
Galectin‐3 and suppression of tumorigenicity 2: Two emerging cardiac biomarkers that may be predictors of cardiac fibrosis development in sport	7
Beyond the horizon: Why space biology is the next great innovation opportunity	7
Control of blood pressure in the cold: differentiation of skin and skeletal muscle vascular resistance	7
The renal vasodilatation from β‐adrenergic activation in vivo in rats is not driven by KV7 and BKCa channels	7
Climate change, healthy ageing and the health crisis: is wisdom the link?	7
Issue Information	7
The effect of female breast surface area on skin stiffness and tactile sensitivity at rest and following exercise in the heat	7
Computing muscle mechanical state variables from combined proprioceptive sensory feedback	7
Computational study of the excitation of human induced pluripotent stem cell‐derived cardiomyocytes	7
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials	7
Lower limb hyperthermia augments functional hyperaemia during small muscle mass exercise similarly in trained elderly and young humans	7
NEX4EX – A novel exercise device enabling resistive, plyometric and sensorimotor training during deep‐space missions: A case report	7
The effect of artificial gravity on the outcome of a two‐week resistance vibration exercise programme: BRAVE study	7
Exercise‐induced effects on atherogenesis and tryptophan catabolism via the kynurenine pathway in an HIV‐associated atherosclerosis mouse model	7
Individual assessment of ventilatory acclimatization at high altitude	7
	7
Passive heat intervention research in women: Systematic review and audit of female representation	7
Energy expenditure, intake and availability in female soccer players via doubly labelled water: Are we misrepresenting low energy availability?	7
Use of transcutaneous spinal cord stimulation to explore inhibitory and facilitatory circuits in muscles of the human lower limb	7
Exercise oximetry in clinical practice: A single‐centre perspective on procedure and techniques	7
Spontaneous Ca 2+ signals in the developing mammalian cochlea of live mice under different anaesthetic regimes	7
	6
Durability as an index of endurance exercise performance: Methodological considerations	6
Exertional heat stroke: nutritional considerations	6
Cardiovascular and respiratory evaluation in adenosine A2A receptor knockout mice submitted to short‐term sustained hypoxia	6
The importance of high‐quality heat adaptation research in females	6
On the mechanism of control of the pulse rate	6
	6
Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults	6
Issue Information	6
The sympathetic nervous system in healthy and hypertensive pregnancies: physiology or pathology?	6
The differential sensitivity of the hypothalamic–hypophysial–ovarian axis to 5‐hydroxytryptophan alters the secretion of estradiol	6
Breath‐by‐breath measurement of alveolar gas exchange must preserve mass balance and conform to a physiological definition of a breath	6
Locomotor muscle dysfunction and rehabilitative exercise training in fibrotic interstitial lung disease: Where are we at and where could we go?	6
Bridging brain, respiratory, and locomotor muscle: Integrated view of between‐sex differences during exercise	6
Issue Information	6
Physiology of lived experience: Boston wrong: A series of physiological calamities at the Boston Marathon	6
Reply to Veerkamp et al.: Comments on Harkness‐Armstrong et al. (2021)	6
Passive heat therapy is feasible but does not affect cardiometabolic health outcomes in persons with spinal cord injury – a pilot study	6
Skin wetness perception across body sites in children and adolescents aged 7–16 years old	6
Why is the muscle spindle so complicated?	6
TRPV1 blockade restores the baroreflex control of renal sympathetic nerve activity in cisplatin‐induced renal injury in rats	6
Epigenetic responses to heat: From adaptation to maladaptation	6
Myths and methodologies: Assessing glycaemic control and associated regulatory mechanisms in human physiology research	6
Synbiotic supplementation ameliorates anxiety and myocardial ischaemia–reperfusion injury in hyperglycaemic rats by modulating gut microbiota	6
Stabilising function of the human diaphragm in response to involuntary augmented breaths induced with or without lower‐limb movements	6
Klotho, the Greek goddess controlling the fate of skeletal muscle satellite cells	6
Cerebral blood flow regulation, central arterial stiffness and traumatic brain injury: Effects of aerobic exercise training	6
Water and wisdom: Hydration as a defence against dementia	6
Measuring pulmonary oxygen uptake kinetics: Contemporary perspectives	6
Effect of live‐high, train‐low strategy induced by chronic low‐dose carbon monoxide exposure on haematological parameters and performance in trained individuals	6
Race and ethnicity in physiological research: When socio‐political constructs and biology collide	6
Submaximal 2‐day cardiopulmonary exercise testing to assess exercise capacity and post‐exertional symptom exacerbation in people with long COVID	6
Blood flow restriction training attenuates changes in local muscle endurance: At odds with previous work?	6
	6
Effects of hyperprotein diet on anxiety, haemodynamics and morphofunctional aspects of the heart of Wistar rats	6
Blood flow restriction exercise during microgravity exposure in parabolic flight	6
Cell‐free DNA kinetics in response to muscle‐damaging exercise: A drop jump study	6
Using modified Fenn diagrams to assess ventilatory acclimatization during ascent to high altitude: Effect of acetazolamide	6
From discovery to innovation in physiological research	6
Cardiopulmonary function in special operations forces compared to conventional infantry soldiers	6
Acute and long‐term effect of specific and non‐specific exercises in patients with chronic neck pain: A protocol for a randomized controlled trial	6
Possible protective effect of zinc administration on renal and cognitive changes occurring in uninephrectomized adult male Wistar rats	5
Blistering barnacles: Space physiology in The Adventures of Tintin	5
Issue Information	5
Neural control of coronary artery blood flow by non‐adrenergic and non‐cholinergic mechanisms	5
Effect of prolonged sitting on dynamic cerebral autoregulation in the anterior and posterior cerebral circulations	5
Early chronotype with metabolic syndrome favours resting and exercise fat oxidation in relation to insulin‐stimulated non‐oxidative glucose disposal	5
Therapeutic potential of okra ( Abelmoschus esculentus ) in dysglycaemia and metabolic dysfunction: A systematic review and meta‐analysis across the diab	5
Physiological influences on neurovascular coupling: A systematic review of multimodal imaging approaches and recommendations for future study designs	5
Attenuation of muscle spindle firing with artificially increased series compliance during stretch of relaxed muscle	5
Effects of repeated cryostimulation exposures on sleep quality in swimmers during an intense training period	5
Oxygen diffusion kinetics, buffering capacity and phenotype: A narrative review of oxygen physiology and later phenotype in very preterm infants	5
Size, more than oxygen need, determines the number of capillaries around a muscle fibre	5
Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells	5
Is the blood pressure response to exercise associated with the motor unit firing patterns of the exercised muscle?	5
Acute effects of insulin and insulin‐induced hypoglycaemia on carotid body chemoreceptor activity and cardiorespiratory responses in dogs	5
	5
Is altitude‐induced polycythaemia an unintended evolutionary mistake?	5
Membrane progesterone and oestrogen receptors modulate GABAergic transmission in the prefrontal cortex of prepubertal male, but not female, mice	5
Is there reversible dimerization of albumin in blood plasma? And does it matter?	5
Role of proprioceptors in chronic musculoskeletal pain	5
Cardiovascular, respiratory and splenic responses to rebreathing and apnoea during exercise	5
On the challenge of assessing dynamic cerebral autoregulation	5
Implementation of a coagulation component into a phosphate kinetics model in haemodialysis therapy: A tool for detection of clotting problems?	5
Impact of obesity and an obesogenic environment on cardiotoxin‐induced damage and recovery of human myotubes	5
Ketone monoester attenuates oxygen desaturation during weighted ruck exercise under acute hypoxic exposure but does not impact cognitive performance	5
Diffusion and physical constraints limit oxidative capacity, capillary supply and size of muscle fibres in mice and humans	5
Adaptive mediolateral control during split‐belt walking: Energetics of interlimb coordination and enhanced savings following acute intermittent hypoxia	5
Evaluation of metabolism‐related molecules in rat model of autism spectrum disorders	5
Estimated exercise‐induced maximal myocardial blood flow in untrained and endurance‐trained men	5
Physical exercise intervention in glycogen storage disease IIIa: Feasibility and multisystem benefits	5
Acute metabolic responses to high‐intensity interval training in men with overweight or obesity: Does the exercise modality matter?	5
When rehabilitation is not enough, how targeting metabolism can overcome the limited plasticity of skeletal muscle after traumatic injury	5