Experimental Physiology

Article	Citations
Physiological sex differences affect the integrative response to exercise: acute and chronic implications	164
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research	95
Long COVID: mechanisms, risk factors and recovery	79
Carotid stiffness, intima–media thickness and aortic augmentation index among adults with SARS‐CoV‐2	48
Human brown adipose tissue: Classical brown rather than brite/beige?	42
Individual risk factors associated with exertional heat illness: A systematic review	34
The effect of microgravity on the human venous system and blood coagulation: a systematic review	32
Endurance exercise‐induced and mental fatigue and the brain	32
Long non‐coding RNA PRRT3‐AS1 silencing inhibits prostate cancer cell proliferation and promotes apoptosis and autophagy	31
Short‐term high‐intensity interval training exercise does not affect gut bacterial community diversity or composition of lean and overweight men	29
Five weeks of heat training increases haemoglobin mass in elite cyclists	28
Mechanical work as a (key) determinant of energy cost in human locomotion: recent findings and future directions	28
The role of lactate in sepsis and COVID‐19: Perspective from contracting skeletal muscle metabolism	27
Task‐specific strength increases after lower‐limb compound resistance training occurred in the absence of corticospinal changes in vastus lateralis	24
The 2018 Global Research Expedition on Altitude Related Chronic Health (Global REACH) to Cerro de Pasco, Peru: an Experimental Overview	24
Biological and methodological factors affecting response variability to endurance training and the influence of exercise intensity prescription	23
Combination of quercetin and exercise training attenuates depression in rats with 1,2‐dimethylhydrazine‐induced colorectal cancer: Possible involvement of inflammation and BDNF signalling	22
‘White Mars’ – nearly two decades of biomedical research at the Antarctic Concordia station	22
Secondary endings of muscle spindles: Structure, reflex action, role in motor control and proprioception	22
Physiological complexity: influence of ageing, disease and neuromuscular fatigue on muscle force and torque fluctuations	22
The influence of age and sex on cerebrovascular reactivity and ventilatory response to hypercapnia in children and adults	22
Nutritional approaches to counter performance constraints in high‐level sports competition	21
Natural killer cell mobilization and egress following acute exercise in men with prostate cancer	21
Physiological basis of interval training for performance enhancement	21
Development of the gut microbiome in early life	21

Effect of high intensity interval training on body composition in women before and after menopause: a meta‐analysis	21
Impact of passive heat acclimation on markers of kidney function during heat stress	20
Mechanical ventilation in COVID‐19: A physiological perspective	19
Epigenetic responses to heat: From adaptation to maladaptation	19
Inhibitory role of long non‐coding RNA OIP5‐AS1 in rheumatoid arthritis progression through the microRNA‐448–paraoxonase 1–toll‐like receptor 3–nuclear factor κB axis	19
Progesterone decreases apnoea and reduces oxidative stress induced by chronic intermittent hypoxia in ovariectomized female rats	18
Splenic responses to a series of repeated maximal static and dynamic apnoeas with whole‐body immersion in water	18
Cerebral blood flow, cerebrovascular reactivity and their influence on ventilatory sensitivity	18
Exertional heat stroke in sport and the military: epidemiology and mitigation	17
Blood‐flow‐restricted exercise: Strategies for enhancing muscle adaptation and performance in the endurance‐trained athlete	17
microRNA‐143‐3p regulates odontogenic differentiation of human dental pulp stem cells through regulation of the osteoprotegerin–RANK ligand pathway by targeting RANK	17
Quantification of testosterone‐dependent erythropoiesis during male puberty	17
Augmented resting beat‐to‐beat blood pressure variability in young, healthy, non‐Hispanic black men	17
LncRNA NEAT1 accelerates renal tubular epithelial cell damage by modulating mitophagy via miR‐150‐5p–DRP1 axis in diabetic nephropathy	16
MicroRNA‐424‐5p regulates aortic smooth muscle cell function in atherosclerosis by blocking APOC3‐mediated nuclear factor‐κB signalling pathway	15
Contact events in rugby union and the link to reduced cognition: evidence for impaired redox‐regulation of cerebrovascular function	15
Evidence for age‐related differences in heat acclimatisation responsiveness	15
Oestradiol affects skeletal muscle mass, strength and satellite cells following repeated injuries	15
Evidence for impaired chronotropic responses to and recovery from 6‐minute walk test in women with post‐acute COVID‐19 syndrome	15
Variability in exercise tolerance and physiological responses to exercise prescribed relative to physiological thresholds and to maximum oxygen uptake	15
Human immune cell mobilization during exercise: effect of IL‐6 receptor blockade	14
Zucker Diabetic‐Sprague Dawley (ZDSD) rat: Type 2 diabetes translational research model	14
‘Fit for surgery’: the relationship between cardiorespiratory fitness and postoperative outcomes	14
The effects of high altitude ascent on splenic contraction and the diving response during voluntary apnoea	14
The effect of heat therapy on blood pressure and peripheral vascular function: A systematic review and meta‐analysis	14
A network physiology approach to oxygen saturation variability during normobaric hypoxia	14
A sympathetic view of blood pressure control at high altitude: new insights from microneurographic studies	13
Individual variation of follicular phase changes in endothelial function across two menstrual cycles	13
Acute phase response to exertional heat stroke in mice	13
Extracting new information from old waveforms: Symmetric projection attractor reconstruction: Where maths meets medicine	13
Global REACH 2018: Andean highlanders, chronic mountain sickness and the integrative regulation of resting blood pressure	13
Exertional heat stroke: an evidence based approach to clinical assessment and management	13
Are there sex differences in risk for exertional heat stroke? A translational approach	13
Achieving energy balance with a high‐fat meal does not enhance skeletal muscle adaptation and impairs glycaemic response in a sleep‐low training model	13
Knockout of MD1 contributes to sympathetic hyperactivity and exacerbates ventricular arrhythmias following heart failure with preserved ejection fraction via NLRP3 inflammasome activation	12
Forearm vasodilatation to a β2‐adrenergic receptor agonist in premenopausal and postmenopausal women	12
Swimming exercise decreases depression‐like behaviour and inflammatory cytokines in a mouse model of type 2 diabetes	12
Myths and methodologies: Degrees of freedom – limitations of infrared thermographic screening for Covid‐19 and other infections	12
Extracellular vesicles released from stress‐induced prematurely senescent myoblasts impair endothelial function and proliferation	12
The gut hormone secretin triggers a gut–brown fat–brain axis in the control of food intake	12
Improving the prognosis of renal patients: The effects of blood flow‐restricted resistance training on redox balance and cardiac autonomic function	12
MiR‐92b‐3p regulates oxygen and glucose deprivation–reperfusion‐mediated apoptosis and inflammation by targeting TRAF3 in PC12 cells	12
Changes in vastus lateralis fibre cross‐sectional area, pennation angle and fascicle length do not predict changes in muscle cross‐sectional area	12
Sex differences in the vascular response to sympathetic activation during acute hypoxaemia	11
Young plasma administration mitigates depression‐like behaviours in chronic mild stress‐exposed aged rats by attenuating apoptosis in prefrontal cortex	11
Resting skeletal muscle PNPLA2 (ATGL) and CPT1B are associated with peak fat oxidation rates in men and women but do not explain observed sex differences	11
Repeated bouts of resistance exercise in rats alter mechanistic target of rapamycin complex 1 activity and ribosomal capacity but not muscle protein synthesis	11
Examining interindividual differences in select muscle and whole‐body adaptations to continuous endurance training	11
Altered central and peripheral haemodynamics during rhythmic handgrip exercise in young adults with SARS‐CoV‐2	11
Effect of aerobic fitness on the relation between age and whole‐body heat exchange during exercise‐heat stress: a retrospective analysis	11

Central and peripheral muscle fatigue following repeated‐sprint running in moderate and severe hypoxia	11
The importance of bone marrow and the immune system in driving increases in blood pressure and sympathetic nerve activity in hypertension	11
Myths and methodologies: The use of equivalence and non‐inferiority tests for interventional studies in exercise physiology and sport science	11
Indices of acceleration atelectasis and the effect of hypergravity duration on its development	10
Effects of sex and menstrual cycle on sweating during isometric handgrip exercise and postexercise forearm occlusion	10
Young black women demonstrate impaired microvascular but preserved macrovascular function compared to white women	10
Modern physiology vindicates Darwin's dream	10
Oh G: The x, y and z of human physiological responses to acceleration	10
Exercise in hypobaric hypoxia increases markers of intestinal injury and symptoms of gastrointestinal distress	10
Inhibition of EZH2 attenuates coronary heart disease by interacting with microRNA‐22 to regulate the TXNIP/nuclear factor‐κB pathway	10
Non‐invasive peripheral focused ultrasound neuromodulation of the celiac plexus ameliorates symptoms in a rat model of inflammatory bowel disease	10
Ventricular contraction and relaxation rates during muscle metaboreflex activation in heart failure: are they coupled?	10
Acute physiological and psychophysical responses to different modes of heat stress	10
Directional sensitivity of the cerebral pressure–flow relationship in young healthy individuals trained in endurance and resistance exercise	10
Biomarkers of heatstroke‐induced organ injury and repair	10
Elite female athlete research: stop searching for the ‘magic P’	10
Exercise and insulin‐like growth factor 1 supplementation improve angiogenesis and angiogenic cytokines in a rat model of diabetes‐induced neuropathy	10
Integrative crosstalk between hypoxia and the cold: Old data and new opportunities	10
Oncostatin M upregulates Livin to promote keratinocyte proliferation and survival via ERK and STAT3 signalling pathways	10
Effect of treatment with carvacrol and aerobic training on cardiovascular function in spontaneously hypertensive rats	9
The within‐ and between‐day reliability of cerebrovascular reactivity using traditional and novel analytical approaches	9
Contrasting effects of heat stress on neuromuscular performance	9
How do exercise training variables stimulate processes related to mitochondrial biogenesis in slow and fast trout muscle fibres?	9
microRNA‐22‐3p plays a protective role in a murine asthma model through the inhibition of the NLRP3–caspase‐1–IL‐1β axis	9
Prior viral illness increases heat stroke severity in mice	9
Neuromuscular fatigability amplitude and aetiology are interrelated across muscles	9
Chronic stress induced perivascular adipose tissue impairment of aortic function and the therapeutic effect of exercise	9
Human amniotic membrane mesenchymal stem cell‐conditioned medium reduces inflammatory factors and fibrosis in ovalbumin‐induced asthma in mice	9
The stability of cerebrovascular CO2 reactivity following attainment of physiological steady‐state	9
Cardiorespiratory hysteresis during incremental high‐altitude ascent–descent quantifies the magnitude of ventilatory acclimatization	9
Placental adaptations supporting fetal growth during normal and adverse gestational environments	9
Heartbeats entrain breathing via baroreceptor‐mediated modulation of expiratory activity	9
Epidural stimulation for cardiovascular function increases lower limb lean mass in individuals with chronic motor complete spinal cord injury	9
Involvement of the lncRNA AFAP1‐AS1/microRNA‐195/E2F3 axis in proliferation and migration of enteric neural crest stem cells of Hirschsprung's disease	9
Short‐term very low caloric intake causes endothelial dysfunction and increased susceptibility to cardiac arrhythmias and pathology in male rats	9
Social isolation is a direct determinant of decreased home‐cage activity in mice: A within‐subjects study using a body‐implantable actimeter	9
Ageing reduces skin wetness sensitivity across the body	9
MicroRNA‐188 inhibits biological activity of lung cancer stem cells through targeting MDK and mediating the Hippo pathway	9
When mechanical work meets energetics: Obese versus non‐obese children walking	9
Extreme occupational heat exposure is associated with elevated haematological and inflammatory markers in Fire Service Instructors	8
Physical exercise increases global and gene‐specific (interleukin‐17 and interferon‐γ) DNA methylation in lymphocytes from aged women	8
Prone positioning redistributes gravitational stress in the lung in normal conditions and in simulations of oedema	8
Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D‐deficient men, independent of age	8
Intermittent reloading does not prevent reduction in iron availability and hepcidin upregulation caused by hindlimb unloading	8
A milk casein hydrolysate‐derived peptide enhances glucose uptake through the AMP‐activated protein kinase signalling pathway in skeletal muscle cells	8
Breath holding as an example of extreme hypoventilation: experimental testing of a new model describing alveolar gas pathways	8
AGEs–RAGE axis mediates myocardial fibrosis via activation of cardiac fibroblasts induced by autophagy in heart failure	8
Impact of early life development on later onset chronic kidney disease and hypertension and the role of evolutionary trade‐offs	8
Heat acclimation during low‐intensity exercise increases and Hsp72, but not markers of mitochondrial biogenesis and oxidative phosphorylation, in skeletal tissue	8
A5 noradrenergic‐projecting C1 neurons activate sympathetic and breathing outputs in anaesthetized rats	8
Obesity and exercise training alter inflammatory pathway skeletal muscle small extracellular vesicle microRNAs	8
Protective mechanism of demethylase fat mass and obesity‐associated protein in energy metabolism disorder of hypoxia–reoxygenation‐induced cardiomyocytes	8
COVID‐19 vulnerabilities are intensified by declining human serum albumin levels	8
Multivariate analysis of the systemic response to auditory stimulation: An integrative approach	8
Early chronotype with metabolic syndrome favours resting and exercise fat oxidation in relation to insulin‐stimulated non‐oxidative glucose disposal	8
Graded reductions in pre‐exercise glycogen concentration do not augment exercise‐induced nuclear AMPK and PGC‐1α protein content in human muscle	8
Acute and chronic cardiac adaptations in adults born preterm	8
Regional variation in the reliability of sweat rate measured via the ventilated capsule technique during passive heating	8
Unveiling women's powerhouse	8
The effect of acute intermittent hypoxia on human limb motoneurone output	8
Do females and males exhibit a similar sarcopenic response as a consequence of normoxic and hypoxic bed rest?	8
The influence of habitual endurance exercise on carotid artery strain and strain rate in young and middle‐aged men	8
Older adults show elevated intermuscular coherence in eyes‐open standing but only young adults increase coherence in response to closing the eyes	8
The eye in extreme environments	8
Temporal changes in pulmonary gas exchange efficiency when breath‐hold diving below residual volume	7
Short‐term effects of electronic cigarettes on cerebrovascular function: A time course study	7
The parotid secretory protein BPIFA2 is a salivary surfactant that affects lipopolysaccharide action	7
The role of muscle mechano and metaboreflexes in the control of ventilation: breathless with (over) excitement?	7
The miRNA‐143‐3p–Sox6–Myh7 pathway is altered in obesogenic diet‐induced cardiac hypertrophy	7
COVID‐19 coagulopathy – what should we treat?	7
Acute moderate‐intensity aerobic exercise promotes purinergic and inflammatory responses in sedentary, overweight and physically active subjects	7
Glycogen supercompensation is due to increased number, not size, of glycogen particles in human skeletal muscle	7
The effect of autologous repair and voluntary wheel running on force recovery in a rat model of volumetric muscle loss	7
Association between effective neural drive to the triceps surae and fluctuations in plantar‐flexion torque during submaximal isometric contractions	7
Perivascular adipose tissue: An immune cell metropolis	7
Analgesic effect of dexmedetomidine in rats after chronic constriction injury by mediating microRNA‐101 expression and the E2F2–TLR4–NF‐κB axis	7
The impact of damage‐associated molecular patterns on the neurotransmitter release and gene expression in the ex vivo rat carotid body	7
Role of hydrogen sulfide in ventilatory responses to hypercapnia in the medullary raphe of adult rats	7
Treatment effects of the combination of ceftriaxone and valproic acid on neuronal and behavioural functions in a rat model of epilepsy	7
Protein‐carbohydrate ingestion alters Vps34 cellular localization independent of changes in kinase activity in human skeletal muscle	7

Comparison of preventive and therapeutic effects of continuous exercise on acute lung injury induced with methotrexate	7
Lipid peroxidation in the descending thoracic aorta of rats deprived of REM sleep using the inverted flowerpot technique	7
The effects of hypoxia and fatigue on skeletal muscle electromechanical delay	7
Acute effects of insulin and insulin‐induced hypoglycaemia on carotid body chemoreceptor activity and cardiorespiratory responses in dogs	7
Mind affects matter: Hindbrain GLP1 neurons link stress, physiology and behaviour	7
Sex differences in the incidence and mode of death in rats with heart failure with preserved ejection fraction	7
Reliability of the hyperaemic response to passive leg movement in young, healthy women	7
Peripheral chemoresponsiveness during exercise in male athletes with exercise‐induced arterial hypoxaemia	7
Previous recreational cold exposure does not alter endothelial function or sensory thermal thresholds in the hands or feet	6
Hypoxia gradually augments metabolic and thermoperceptual responsiveness to repeated whole‐body cold stress in humans	6
Endurance exercise plus overload induces fatigue resistance and similar hypertrophy in mice irrespective of muscle mass	6
Oxygen transport and utilisation during exercise in cystic fibrosis: contributors to exercise intolerance	6
Changes in prefrontal cerebral oxygenation and microvascular blood volume in hypoxia and possible association with acute mountain sickness	6
The interplay between gastrocnemius medialis force–length and force–velocity potentials, cumulative EMG activity and energy cost at speeds above and below the walk to run transition speed	6
Swimming training improves cardiovascular autonomic dysfunctions and prevents renal damage in rats fed a high‐sodium diet from weaning	6
Impact of resveratrol‐mediated increase in uterine artery blood flow on fetal haemodynamics, blood pressure and oxygenation in sheep	6
Identifying responders versus non‐responders: Incorporation of controls is required for sound statistical inference	6
Are humans evolved specialists for running in the heat? Man vs. horse races provide empirical insights	6
hsa_circ_001653 up‐regulates NR6A1 expression and elicits gastric cancer progression by binding to microRNA‐377	6
LncRNA MIAT promotes hypoxia‐induced H9C2 cell pyroptosis via binding to SF1 to inhibit CGRP transcription	6
The oestrous cycle and skeletal muscle atrophy: Investigations in rodent models of muscle loss	6
Impaired pulmonary gas exchange efficiency, but normal pulmonary artery pressure increases, with hypoxia in men and women with a patent foramen ovale	6
Hide and seek in a pandemic: review of SARS‐CoV‐2 infection and sequelae in children	6
Differential shifts in baroreflex control of renal and lumbar sympathetic nerve activity induced by freezing behaviour in rats	6
The sweat glands’ maximum ion reabsorption rates following heat acclimation in healthy older adults	6
Early initiation of electrical stimulation paired with range of motion after a volumetric muscle loss injury does not benefit muscle function	6
GABA‐ergic agents modulated the effects of histamine on the behaviour of male mice in the elevated plus maze test	6
The acute effect of resistance exercise on limb blood flow	6
The ventilatory component of the muscle metaboreflex: catch me if you can!	6
Nutraceutical and pharmaceutical cocktails did not preserve diaphragm muscle function or reduce muscle damage in D2‐mdx mice	6
Therapeutic benefits of proning to improve pulmonary gas exchange in severe respiratory failure: focus on fundamentals of physiology	6
Effects of long‐term immobilisation on endomysium of the soleus muscle in humans	6
Combination of curcumin with autologous transplantation of adult neural stem/progenitor cells leads to more efficient repair of damaged cerebral tissue of rat	6
Control of blood pressure in the cold: differentiation of skin and skeletal muscle vascular resistance	6
Metabolic and microvascular function assessed using near‐infrared spectroscopy with vascular occlusion in women: age differences and reliability	6
The acute effect of high‐ and moderate‐intensity interval exercise on vascular function before and after a glucose challenge in adolescents	6
In pursuit of the unicorn	6
Assessing central and peripheral respiratory chemoreceptor interaction in humans	6
In vivo manipulation of muscle shape and tendinous stiffness affects the human ability to generate torque rapidly	6
Comparison of skeletal muscle ultrastructural changes between normal and blood flow‐restricted resistance exercise: A case report	6
Near‐infrared spectroscopy measures of sternocleidomastoid blood flow during exercise and hyperpnoea	6
Comparison of murine behavioural and physiological responses after forced exercise by electrical shock versus manual prodding	5
Myths and methodologies: Reliability of forearm cutaneous vasodilatation measured using laser‐Doppler flowmetry during whole‐body passive heating	5
Fibrinogen‐like protein 2 contributes to normal murine cardiomyocyte maturation and heart development	5
Justicia flava leaf extract potently relaxes pregnant human myometrial contractility: a lead plant for drug discovery of new tocolytic drugs	5
Bionic women and men ‐ Part 1: Cardiovascular lessons from heart failure patients implanted with left ventricular assist devices	5
Young, non‐Hispanic Black men and women exhibit divergent peripheral and cerebral vascular reactivity	5
Vasodilatation by carbon dioxide and sodium nitroglycerin reduces compliance of the cerebral arteries in humans	5
Two weeks of remote ischaemic preconditioning alters sympathovagal balance in healthy humans	5
Platelet‐rich plasma affects gap junctional features in myofibroblasts in vitro via vascular endothelial growth factor (VEGF)‐A/VEGF receptor	5
Palatable food access impacts expression of amylin receptor components in the mesocorticolimbic system	5
Sex differences in soleus muscle H‐reflex and V‐wave excitability	5
Time course of neuromuscular responses to acute hypoxia during voluntary contractions	5
Causal analyses to study autonomic regulation during acute head‐out water immersion, head‐down tilt and supine position	5
Effect of high‐intensity interval training on cardiometabolic component risks in persons with paraplegia: Protocol for a randomized controlled trial	5
Influence of cuff‐occlusion duration on contrast‐enhanced ultrasound assessments of calf muscle microvascular blood flow responsiveness in older adults	5
Regional functional and structural abnormalities within the aorta as a potential driver of vascular disease in metabolic syndrome	5
The long‐term impact of ovariectomy on ventilation and expression of phrenic long‐term facilitation in female rats	5
Changes in the autonomic and respiratory patterns in mice submitted to short‐term sustained hypoxia	5
Combined methazolamide and theophylline improves oxygen saturation but not exercise performance or altitude illness in acute hypobaric hypoxia	5
Sympathetic regulation of coronary circulation during handgrip exercise and isolated muscle metaboreflex activation in men	5
Skeletal muscle ferritin abundance is tightly related to plasma ferritin concentration in adults with obesity	5
Exogenous ketone supplementation: an emerging tool for physiologists with potential as a metabolic therapy	5
Factors associated with electrical stimulation‐induced performance fatigability are dependent upon stimulation location	5
Sympathetic vasomotor outflow during low‐intensity leg cycling in healthy older males	5
Frequency‐dependent characteristics of nerve‐mediated ATP and acetylcholine release from detrusor smooth muscle	5
Remote liver ischaemic preconditioning protects rat brain against cerebral ischaemia–reperfusion injury by activation of an AKT‐dependent pathway	5
Microbiomes in physiology: insights into 21st‐century global medical challenges	5
Overexpression of Dnmt3a ameliorates diabetic muscle atrophy by modulating the Pten/Akt pathway	5
In vivo operating lengths of the gastrocnemius muscle during gait in children who idiopathically toe‐walk	5
Increased myofilament calcium sensitivity is associated with decreased cardiac troponin I phosphorylation in the diabetic rat heart	5
Lower‐body dynamic exercise reduces wave reflection in healthy young adults	5
From pigeon holes to descending spirals: a paradigm of physiology, cognitive performance and behaviour in extreme environments	5
Inhibition of the glycogen synthase kinase 3β–hypoxia‐inducible factor 1α pathway alleviates NLRP3‐mediated pyroptosis induced by high glucose in renal tubular epithelial cells	5
Notch, Numb and Numb‐like responses to exercise‐induced muscle damage in human skeletal muscle	5
Gonadotrophin‐releasing hormone receptor autoantibodies induce polycystic ovary syndrome‐like features in a rat model	5
The acute effect of a laboratory shame induction protocol on endothelial function in young, healthy adults	5
Prefrontal dopaminergic system and its role in working memory and cognition in spinal cord‐injured rats	5
Platelet releasate normalises the compromised muscle regeneration in a mouse model of hyperlipidaemia	5
Placenta‐targeted treatment in hypoxic dams improves maturation and growth of fetal cardiomyocytes in vitro via the release of placental factors	5
Remote limb ischaemic conditioning produces cardioprotection in rats with testicular ischaemia–reperfusion injury	5
Physiological regulation of bone length and skeletal proportion in mammals	5
Exercise response variability: Random error or true differences in exercise response?	5