Experimental Physiology

Article	Citations
	172
Nitrite supplementation alleviates cerebrovascular dysfunction in chronically stressed mice, but cognitive decline remains	82
Chasing genes at high‐altitude	69
Using environmental and exercise physiology to address gender inequalities in climate change and occupational health research	57
Erratum	54
Physiological assessment of a 16 day, 4385 km ultra‐endurance mountain bike race: A case study	44
Chitinase 3‐like 1 overexpression aggravates hypoxia–reoxygenation injury in IEC‐6 cells by inhibiting the PI3K/AKT signalling pathway	34
The physiology of survival: Fluid and food	34
Myths and methodologies: Considerations for evaluating the time course of thermoregulatory adaptation during heat acclimation	33
Investigating the control of exercise hyperpnoea: A synergy of contributions	30
ZFP36 inhibits the pro‐apoptotic effects of transforming growth factor β1 on mitral valve interstitial cells via the GTP‐binding protein 6 pathway in mitral valve prolapse	29
Acute heat stress amplifies exercise‐induced metabolomic perturbations and reveals variation in circulating amino acids in endurance‐trained males	27
To Mars through LEO: How commercial space travel will change exploration‐enabling research	26
The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis	26
Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut–athlete on Mars exploration missions	25
Dietary manipulations for health and the prevention and management of disease: An editorial	25
Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle	24
Low‐load resistance exercise with and without blood flow restriction: Which is more effective for increasing local muscle endurance and why?	22
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Blunted hypoxic pulmonary vasoconstriction in apnoea divers	21
Thermo‐haemodynamic coupling during regional thigh heating: Insight into the importance of local thermosensitive mechanisms in blood circulation	20
Network model of skeletal muscle cell signalling predicts differential responses to endurance and resistance exercise training	20
The miRNA‐143‐3p–Sox6–Myh7 pathway is altered in obesogenic diet‐induced cardiac hypertrophy	20
When is the right time to initiate rehabilitation? Time will tell…	20
How do physiological networks respond to normobaric hypoxia and isometric exercise?	18

No difference in mean middle cerebral artery blood velocity responses between lower‐ and upper‐body unilateral resistance exercise in untrained individuals	18
Interference with glutamate antiporter system xc− enables post‐hypoxic long‐term potentiation in hippocampus	17
Larger reductions in blood pressure during post‐exercise standing, but not middle cerebral artery blood velocity, in resistance‐trained versus untrained individuals	17
Mechanosensory encoding in ex vivo muscle–nerve preparations	16
Muscle fibre size and myonuclear positioning in trained and aged humans	16
Issue Information	16
Acute partial sleep restriction does not impact arterial function in young and healthy humans	16
Issue Information	15
Alpha band oscillations in common synaptic input are explanatory of the complexity of isometric knee extensor muscle torque signals	15
From fatigue to physiology: Submaximal 2‐day cardiopulmonary exercise test and emerging standards in long COVID	15
Dynamic cerebral autoregulation quantification with spontaneous arterial blood pressure oscillations: Is transfer function analysis our best option?	15
Issue Information	15
Even periconceptional alcohol consumption can have long‐term consequences on heart health in the offspring	14
Kidney function and cognitive impairment	14
Habitual exercise in youth: A ʻbrainyʼ idea	14
Central command suppresses pressor‐evoked bradycardia at the onset of voluntary standing up in conscious cats	14
Unlocking the complications of chronic concussion in rugby players: A traumatic tale of cerebral injury	14
The effect of acute intradermal administration of ascorbate on heat loss responses in older adults with uncomplicated controlled hypertension	14
Limited matching of the cardiac output response to the peripheral demand of heat stress and exercise	13
Effect of adrenaline on serum mid‐regional pro‐atrial natriuretic peptide and central blood volume	13
Editorial Board	13
Handgrip exercise does not alter CO2‐mediated cerebrovascular flow‐mediated dilation	13
Is polycystic ovary syndrome associated with elevated muscle sympathetic nerve activity?	13
Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury	13
Comparing 17β‐estradiol and progesterone concentrations in young, physically active females: Insights from plasma versus serum analysis	13
On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur	13
Alveolar deadspace and intrapulmonary shunt in healthy individuals and in individuals who have recovered from COVID‐19 infection	13
Post‐exercise hot or cold water immersion does not alter perception of effort or neuroendocrine responses during subsequent moderate‐intensity exercise	13
Effect of exercise on chronic neck pain and central sensitization: A protocol for a randomized crossover trial	13
Passive thigh heating improves peak force production in younger adults and early isokinetic force production in younger and older adults	12
Issue Information	12
Mapping the variability of in vivo rat uterine electrical properties throughout the oestrous cycle	12
Marie Krogh's contributions to the study of thyroid physiology and pathophysiology	12
Exertional heat stress and intestinal barrier injury: Does chronic disease add fuel to the fire?	12
Bioenergetic profiles and respiratory control in mitochondrial physiology: Precision analysis of oxidative phosphorylation	11
Skin wound healing as a mirror to cardiac wound healing	11
On changes, challenges and collaboration: Introducing a new Editor‐in‐Chief and moving to Open Access	11
In support of the placental programming hypothesis: Placental endocrine insufficiency programs atypical behaviour in mothers and their offspring	11
Issue Information	11
Delineating the impacts of air temperature and humidity for endurance exercise	11
Corrigendum	11
CTRP6‐mediated cardiac protection in heart failure via the AMPK/SIRT1/PGC‐1α signalling pathway	11
Diverse perspectives on respiratory chemoreceptor interactions: Resuscitating an expired debate	11
Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes	11
News, views and where best to choose	11
The contribution of the tendon electrode to M‐wave characteristics in the biceps brachii, vastus lateralis and tibialis anterior	11
‘One for all, all for one’: A tale from the formative years of Scandinavian exercise physiology	10
Response to the letter from Bushfield and Day: Potential pitfalls of using a correction to normative values in the assessment of acid–base compensation during early ascent to high altitude	10
Sex differences in the coronary vascular response to combined chemoreflex and metaboreflex stimulation in healthy humans	10
Insulin‐like growth factor‐1 infusion in preterm piglets does not affect growth parameters of skeletal muscle or tendon tissue	10

The role of orexin A in the pathogenesis of ischaemic stroke at high altitude	10
A crossover control study of three methods of heat acclimation on the magnitude and kinetics of adaptation	10
Association between effective neural drive to the triceps surae and fluctuations in plantar‐flexion torque during submaximal isometric contractions	10
Cardiorespiratory consequences of obesity: a tale of two pumps	10
The severity of acute hypoxaemia determines distinct changes in intracortical and spinal neural circuits	10
Exercise‐induced pain within endurance exercise settings: Definitions, measurement, mechanisms and potential interventions	10
Challenging dynamic cerebral autoregulation across the physiological CO2 spectrum: Influence of biological sex and cardiac cycle	10
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Characterization of differences in immune responses during bolus and continuous infusion endotoxin challenges using mathematical modelling	10
Peripheral nerve‐derived fibroblasts promote neurite outgrowth in adult dorsal root ganglion neurons more effectively than skin‐derived fibroblasts	10
The impact of long‐haul travel and 13 h time change on sleep and rest activity circadian rhythm in speed skaters during World Cup competitions	9
Editorial Board	9
Distinct adaptations of muscle endurance but not strength or hypertrophy to low‐load resistance training with and without blood flow restriction	9
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Short‐term effects of electronic cigarettes on cerebrovascular function: A time course study	9
DYNamic Assessment of Multi‐Organ level dysfunction in patients recovering from COVID‐19: DYNAMO COVID‐19	9
Issue Information	9
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Impaired glucose tolerance and insulin resistance in a prenatally‐androgenized rat model of polycystic ovary syndrome in later life	9
Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest	9
GABA B receptor‐mediated modulation of sensory neuron excitability: Roles of Ca V 2.2, G‐protein‐c	9
A new method for non‐invasive determination of effective pulmonary blood flow and cardiac output in spontaneously breathing subjects	9
The acute effects of dynamic stretching on the neuromuscular system are independent of the velocity	9
Pulmonary vascular reactivity to supplemental oxygen in Sherpa and lowlanders during gradual ascent to high altitude	8
Temporal summation in human peripheral axons when stimulated transcutaneously with a 10‐kHz waveform	8
Gut microbiota in regulation of childhood bone growth	8
RETRACTED: Corrigendum	8
Acute alterations in blood lactate in the setting of transient stress induced myocardial ischaemia	8
Maximal strength and voluntary activation of adductor pollicis after a single session of acute intermittent hypercapnia or acute intermittent hypoxia	8
Caffeine in cerebrovascular research: To withdraw or not to withdraw?	8
Defying gravity: Breath, beat and brain	8
Effect of moderate altitude and nocturnal oxygen therapy on cerebrovascular function in patients with COPD: A randomized, crossover trial at 2048 m	8
Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole‐body passive hyperthermia in healthy humans	8
Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism	8
The acute effect of a laboratory shame induction protocol on endothelial function in young, healthy adults	8
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury	8
A single breath of nitric oxide does not alter pulmonary perfusion pressure	8
Inhibitory effect of oestradiol on the cardiac KV7.1/KCNE1 channel is species dependent	8
Acute high‐intensity muscle contraction moderates AChR gene expression independent of rapamycin‐sensitive mTORC1 pathway in rat skeletal muscle	7
From mechanistic promise to clinical translation: Passive heat therapy as a cardiovascular and functional adjunct in ageing and disease	7
Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression	7
Issue Information	7
Computing muscle mechanical state variables from combined proprioceptive sensory feedback	7
Memory impairment in the D2.mdx mouse model of Duchenne muscular dystrophy is prevented by the adiponectin receptor agonist ALY688	7
Vascular limitations in blood pressure regulation with age in women: Insights from exercise and acute cardioselective β‐blockade	7
GST polymorphism as a predictive biomarker for modulating the susceptibility to chronic obstructive pulmonary disease: A North Indian study	7
Oral ketone monoester supplementation does not accelerate recovery of muscle force or modulate circulating cytokine concentrations after muscle‐damaging eccentric exercise in healthy males and females	7
Effect of internal and external cooling on high‐intensity intermittent cycling performance and cognitive function in the heat	7
Issue Information	7
Issue Information	7
Functional assays reflective of cancer hallmarks in BT‐549 cells are not impacted by media supplemented with exercise‐trained plasma	7
Changes in motor unit behaviour across repeated bouts of eccentric exercise	7
Spectral changes in skin blood flow during pressure manipulations or sympathetic stimulation	7
Knee movements cause changes in the firing behaviour of muscle spindles located within the mono‐articular ankle extensor soleus in the rat	7
Cerebral haemodynamic responses to inspiratory muscle work	7
Lower vascular conductance responses to handgrip exercise are improved following acute antioxidant supplementation in young individuals with post‐traumatic stress disorder	7
Issue Information	6
Submaximal 2‐day cardiopulmonary exercise testing to assess exercise capacity and post‐exertional symptom exacerbation in people with long COVID	6
Biomarkers of heatstroke‐induced organ injury and repair	6
The effect of exercise in a fasted state on plasma low‐density lipoprotein cholesterol concentrations in males and females	6
Issue Information	6
ZDF (fa/fa) rats show increasing heterogeneity in main parameters during ageing, as confirmed by biometrics, oxidative stress markers and MMP activity	6
Sex differences in the ventilatory responses to exercise in mild to moderate obesity	6
The effect of acute intermittent hypoxia on human limb motoneurone output	6
The renal vasodilatation from β‐adrenergic activation in vivo in rats is not driven by KV7 and BKCa channels	6
Control of blood pressure in the cold: differentiation of skin and skeletal muscle vascular resistance	6
Using modified Fenn diagrams to assess ventilatory acclimatization during ascent to high altitude: Effect of acetazolamide	6
The sympathetic nervous system in healthy and hypertensive pregnancies: physiology or pathology?	6
Potential pitfalls of using a correction to normative values for the assessment of acid–base compensation during early ascent to high altitude	6
The effect of protein or amino acid provision on immobilization‐induced muscle atrophy in healthy adults: A systematic review and meta‐analysis	6
Impact of a 12‐week high‐intensity interval training intervention on cardiac structure and function after COVID‐19 at 12‐month follow‐up	6
Stabilising function of the human diaphragm in response to involuntary augmented breaths induced with or without lower‐limb movements	6
Breath‐by‐breath measurement of alveolar gas exchange must preserve mass balance and conform to a physiological definition of a breath	6
Spontaneous Ca2+ signals in the developing mammalian cochlea of live mice under different anaesthetic regimes	6
From discovery to innovation in physiological research	6
Exercise in hypobaric hypoxia increases markers of intestinal injury and symptoms of gastrointestinal distress	6
Applying lessons from limb muscle disuse and ageing to better understand ventilator‐induced diaphragm dysfunction	6
Exercise‐induced effects on atherogenesis and tryptophan catabolism via the kynurenine pathway in an HIV‐associated atherosclerosis mouse model	6
Sarcoplasmic reticulum calcium handling in unbranched, immediately post‐necrotic fast‐twitch mdx fibres is similar to wild‐type littermates	6
Galectin‐3 and suppression of tumorigenicity 2: Two emerging cardiac biomarkers that may be predictors of cardiac fibrosis development in sport	6

Lower limb hyperthermia augments functional hyperaemia during small muscle mass exercise similarly in trained elderly and young humans	6
Synbiotic supplementation ameliorates anxiety and myocardial ischaemia–reperfusion injury in hyperglycaemic rats by modulating gut microbiota	6
The effect of female breast surface area on skin stiffness and tactile sensitivity at rest and following exercise in the heat	6
Heat and carbon monoxide exposure: Is two better than one?	6
Acute intermittent hypoxia in neonatal rodent central nervous system facilitates respiratory frequency through the recruitment of hypothalamic areas	6
Beyond the horizon: Why space biology is the next great innovation opportunity	6
Computational study of the excitation of human induced pluripotent stem cell‐derived cardiomyocytes	6
Climate change, healthy ageing and the health crisis: is wisdom the link?	6
Use of transcutaneous spinal cord stimulation to explore inhibitory and facilitatory circuits in muscles of the human lower limb	6
NEX4EX – A novel exercise device enabling resistive, plyometric and sensorimotor training during deep‐space missions: A case report	6
Energy expenditure, intake and availability in female soccer players via doubly labelled water: Are we misrepresenting low energy availability?	6
Changes in cerebral autoregulation and vasoreactivity after surgical aortic valve replacement: a prospective study	6
Effect of high‐fat diet on isometric, concentric and eccentric contractile performance of skeletal muscle isolated from female CD‐1 mice	6
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Epigenetic responses to heat: From adaptation to maladaptation	6
Individual assessment of ventilatory acclimatization at high altitude	6
The differential sensitivity of the hypothalamic–hypophysial–ovarian axis to 5‐hydroxytryptophan alters the secretion of estradiol	6
Obesity and exercise training alter inflammatory pathway skeletal muscle small extracellular vesicle microRNAs	6
Why is the muscle spindle so complicated?	6
Making sense of the carotid body counter‐regulatory response to hypoglycaemia	5
Klotho, the Greek goddess controlling the fate of skeletal muscle satellite cells	5
Early life stress and hormonal status influence orexin‐1 receptor expression in structures regulating cardiorespiratory responses to CO2	5
A comparison between left ventricular ejection time measurement methods during physiological changes induced by simulated microgravity	5
Reply to Veerkamp et al.: Comments on Harkness‐Armstrong et al. (2021)	5
Blood flow restriction training attenuates changes in local muscle endurance: At odds with previous work?	5
TRPV1 blockade restores the baroreflex control of renal sympathetic nerve activity in cisplatin‐induced renal injury in rats	5
Blood flow restriction exercise during microgravity exposure in parabolic flight	5
Issue Information	5
Cardiopulmonary function in special operations forces compared to conventional infantry soldiers	5
Exertional heat stroke: nutritional considerations	5
Physiology of lived experience: Boston wrong: A series of physiological calamities at the Boston Marathon	5
One minute of light‐intensity stair‐stepping decreases postprandial glycaemia in the evening in non‐diabetic adults: A randomized controlled trial	5
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Respiratory muscle metaboreflex: Connecting the ‘dots’	5
Directional sensitivity of the cerebral pressure–flow relationship in young healthy individuals trained in endurance and resistance exercise	5
Artificial intelligence driven clustering of blood pressure profiles reveals frailty in orthostatic hypertension	5
Skin wetness perception across body sites in children and adolescents aged 7–16 years old	5
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Measuring pulmonary oxygen uptake kinetics: Contemporary perspectives	5
Race and ethnicity in physiological research: When socio‐political constructs and biology collide	5
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Pulmonary diffusing capacity to nitric oxide and carbon monoxide during exercise and in the supine position: a test–retest reliability study	5
Cell‐free DNA kinetics in response to muscle‐damaging exercise: A drop jump study	5
Effects of hyperprotein diet on anxiety, haemodynamics and morphofunctional aspects of the heart of Wistar rats	5
Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults	5
Neuroprotective effects of sinomenine and metformin in diabetic stroke: Role of NLRP3/caspase‐1 and mitophagy	5
Clinical significance and immune microenvironment association of cuproptosis‐related genes in pan‐cancer	5
Diffusion and physical constraints limit oxidative capacity, capillary supply and size of muscle fibres in mice and humans	5
Locomotor muscle dysfunction and rehabilitative exercise training in fibrotic interstitial lung disease: Where are we at and where could we go?	5
Preserved force control by the digits via minimal sparing of cortico‐spinal connectivity after stroke	5
Cardiovascular and respiratory evaluation in adenosine A2A receptor knockout mice submitted to short‐term sustained hypoxia	5
Is the blood pressure response to exercise associated with the motor unit firing patterns of the exercised muscle?	5
Water and wisdom: Hydration as a defence against dementia	5
Issue Information	5
Exercise oximetry in clinical practice: A single‐centre perspective on procedure and techniques	5
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Myths and methodologies: Assessing glycaemic control and associated regulatory mechanisms in human physiology research	5
Acute and long‐term effect of specific and non‐specific exercises in patients with chronic neck pain: A protocol for a randomized controlled trial	5
Interleukin‐15 receptor subunit alpha regulates interleukin‐15 localization and protein expression in skeletal muscle cells	5
Acute effects of insulin and insulin‐induced hypoglycaemia on carotid body chemoreceptor activity and cardiorespiratory responses in dogs	5
Durability as an index of endurance exercise performance: Methodological considerations	5
Faecal microbiome, gastrointestinal integrity, inflammation and thermoregulation in recent exertional heat illness patients and matched controls	5
Reflections on physiology and modelling	4
Immediate cortical glial alterations following spinal cord injury: Evidence from a novel in vitro model	4
Effects of repeated cryostimulation exposures on sleep quality in swimmers during an intense training period	4
EuroSCORE II: Current limitations and physiological gaps in risk stratification	4
Near‐infrared spectroscopy‐derived muscle V̇O2${\dot{V}_{{{\rm{O}}_{\rm{2}}}}}$ kinetics after moderate running exercise in healthy males: reliability and associations with parameters of aerobic fitne	4
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI	4
Insights into pathophysiology and therapeutic strategies for heat stroke: Lessons from a baboon model	4
LGD‐4033 and MK‐677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report	4
Implementation of a coagulation component into a phosphate kinetics model in haemodialysis therapy: A tool for detection of clotting problems?	4
Physical exercise intervention in glycogen storage disease IIIa: Feasibility and multisystem benefits	4
Role of proprioceptors in chronic musculoskeletal pain	4
On the challenge of assessing dynamic cerebral autoregulation	4
Blistering barnacles: Space physiology in The Adventures of Tintin	4
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Platelet‐rich plasma affects gap junctional features in myofibroblasts in vitro via vascular endothelial growth factor (VEGF)‐A/VEGF receptor	4
Science of omics: a molecular space odyssey	4
The evolution of muscle spindles	4
Intensified training augments cardiac function, but not blood volume, in male youth elite ice hockey team players	4
Issue Information	4
Protein‐based perioperative nutrition interventions for improving muscle mass and functional outcomes following orthopaedic surgery	4
When rehabilitation is not enough, how targeting metabolism can overcome the limited plasticity of skeletal muscle after traumatic injury	4
Is there reversible dimerization of albumin in blood plasma? And does it matter?	4
Physiological influences on neurovascular coupling: A systematic review of multimodal imaging approaches and recommendations for future study designs	4
The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat	4
Early chronotype with metabolic syndrome favours resting and exercise fat oxidation in relation to insulin‐stimulated non‐oxidative glucose disposal	4
Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility	4
Effects of furosemide, acetazolamide and amiloride on renal cortical and medullary tissue oxygenation in non‐anaesthetised healthy sheep	4
Exercise breaks prevent attenuation in cerebrovascular function following an acute bout of uninterrupted sitting in healthy children	4
Melanin‐concentrating hormone regulates the hypercapnic chemoreflex by acting in the lateral hypothalamic area	4
Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study	4
Size, more than oxygen need, determines the number of capillaries around a muscle fibre	4
Attenuation of muscle spindle firing with artificially increased series compliance during stretch of relaxed muscle	4
Circadian rhythm of brain‐derived neurotrophic factor in serum and plasma	4