OOIR: Observatory of International Research

Papers

(The TQCC of Blood Coagulation & Fibrinolysis is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
4-Factor prothrombin complex concentrates and factor VIII inhibitor bypass activity use in cardiac surgery	50
Significant difference between coagulation parameters and clinicopathological characteristics in breast cancer	17
Patients with severe coronavirus disease 2019 have high frequency of factor 5 Leiden and prothrombin gene mutations	16
Homozygous MTHFR C677T carriers develop idiopathic portal vein thrombosis 20 years earlier than wild type	13
Characterization of zebrafish coagulation cofactors Fviii and Fv mutants and modeling hemophilia A and factor V deficiency	13
Concurrent congenital hemophilia B and acquired hemophilia A: a unique case report	13
Thromboprophylaxis with argatroban in critically ill patients with sepsis: a review	10
Protein S Erlangen: a novel PROS1 gene mutation associated with quantitative protein S deficiency	10
Genotypes and phenotypes characterization of 17 Iranian patients with inherited factor X deficiency: identification of a novel mutation: Leu487Phe	9
Phenotypic variation in severe hemophilia A is related to endogenous thrombin potential and plasma levels of factor VII	9
Reversal of factor Xa inhibitors associated intracranial haemorrhage at a tertiary medical centre	9
Characterization of antibody clones that bind exclusively to insoluble fibrin	9
Harmonizing factor assay-related testing performed in a large laboratory network	9
Interleukin-10 levels and the risk of thromboembolism according to COMPASS-Cancer associated thrombosis score in breast cancer patients prior to undergoing doxorubicin-based chemotherapy	8
Prenatal diagnosis for hemophilia A (intron 22 inversion) reveals a rare association with Klinefelter syndrome with diagnostic difficulties in molecular interpretation	7
Tissue factor-dependent coagulation activation in intracranial neoplasms: a comparative study	7
Congenital factor V deficiency in Taiwan: identification of a novel variant p.Tyr1813∗ and two variants specific to East Asians	7
Venous thromboembolism in pediatric inflammatory bowel disease: an 11-year population-based nested case–control study in Canada	7
Lupus anticoagulant activity and thrombosis post COVID-19 vaccination	7
Quantifying time from last dose: do direct oral anticoagulant assays correlate with patient's reported last dose	6
Clinical and economic implications of false-positive heparin-induced thrombocytopenia immunoassays: utility of the 4T score	6
Efficacy and relative safety of caplacizumab in immune-mediated thrombotic thrombocytopenic purpura: a systematic review and meta-analysis	6
Effect of hyperbilirubinemia and phototherapy on apoptotic microparticle levels in neonates	6
Increased contact activated endogenous thrombin potential in pregnant women with preeclampsia	6
Bleeding risk in hemophilia A and B carriers: comparison of factor levels determined using chronometric and chromogenic assays	6

Poisoning by butylated hydroxytoluene quinone methide acting as a superwarfarin: first reported case in humans	6
Combination of aspirin and rosuvastatin for reduction of venous thromboembolism in severely injured patients: a double-blind, placebo-controlled, pragmatic randomized phase II clinical trial (The STAT	5
Limited sampling strategies for individualized BAX 855 prophylaxis in severe hemophilia A: in silico evaluation	5
Evaluation of the impact of changes in the autopsy rate on mortality trend of pulmonary embolism, Finland, 1996–2017	5
Real-world comparative effectiveness of dalteparin and enoxaparin for venous thromboembolism prophylaxis	5
A rare case of essential thrombocythemia with pseudo-hyperkalemia	5
Performance evaluation of the Sysmex CN-6000-automated coagulation analyzers for routine coagulation tests	5
The link between high factor VIII to protein C ratio values and poor liver function after major hepatectomy	5
Fibrinogen Aα gene genotyping in patients with inherited afibrinogenemia deficiency; a novel mutation in Iranian afibrinogenemia patients	5
A mild deficiency of ADAMTS13 is associated with severity in COVID-19: comparison of the coagulation profile in critically and noncritically ill patients	4
Assessment of clinical characteristics and treatment outcomes of pediatric patients with intracardiac thrombosis: a single-center experience	4
Endothelium-biomarkers for postthrombotic syndrome: a case–control study	4
Very low-dose recombinant Factor VIIa administration for cardiac surgical bleeding reduces red blood cell transfusions and renal risk: a matched cohort study	4
Use of fibrin monomer and D-Dimer in assessing overt and nonovert disseminated intravascular coagulation	4
Naive haemophilia mice displayed different pattern of cytokine profiles of cytokine profiles changes might be associated with subclinical bleeding	4
New approaches to the genetic study of bleeding diathesis in our center: from sanger to next-generation sequencing	4
New treatments for primary immune thrombocytopenia	4
Eltrombopag treatment for severe immune thrombocytopenia during pregnancy: a case report	4
Anticoagulation management post-transjugular intrahepatic portosystemic shunt in portal hypertension associated with myeloproliferative neoplasms	4
Identification of two novel mutations in three children with congenital factor VII deficiency	4
Thrombogenicity markers for early diagnosis and prognosis in COVID-19: a change from the current paradigm?	4
Two heterozygous mutations associated with type I protein C deficiency in two Chinese independent families	4
Optimizing factor VIII dosing in obese individuals with haemophilia A	4
Expression and methylation status of vascular endothelial growth factor and thrombospondin-1 genes in congenital factor XIII-deficient patients with intracranial hemorrhage	3
Protein S contributes to the paradoxical increase in thrombin generation by low-dose dabigatran in the presence of thrombomodulin	3
Diagnosis of Immunoglobulin G4-related disease in a child with ligneous conjunctivitis: a novel mutation in plasminogen gene and plasminogen activator inhibitor-1 polymorphism	3
Identification of a recurrent missense mutation in the FGA gene likely causing a congenital fibrinogen disorder	3
New developments in the diagnosis of primary immune thrombocytopenia	3
The interplay between hypovitaminosis D and the immune dysfunction in the arteriovenous thrombotic complications of the sever coronavirus disease 2019 (COVID-19) infection	3
A little heparin goes a long way: effect of therapeutic levels of unfractionated heparin on the heparin-induced thrombocytopenia-platelet factor 4 ELISA antibody assay	3
Subcutaneous injection of mRNA vaccines against severe acute respiratory syndrome coronavirus 2: an option for severe bleeding disorders or anticoagulated patients?	3
Comparison of bleeding and ischemic events with apixaban vs. rivaroxaban in triple antithrombotic therapy regimens	3
Coexpression of factor VIII and factor von Willebrand variants in a woman with heavy menstrual bleeding	3
A multicenter, observational study to evaluate hemostasis following recombinant activated FVII treatment in patients in Japan with congenital factor VII deficiency	3
Efficacy of extended microthrombolysis in an elderly lady with purpura fulminans	3
Incidence of factor XII deficiency in critically ill patients with a prolonged activated partial thromboplastin time: a prospective observational study	3
Rotational thromboelastometry for diagnosis of fibrinolysis induced by urokinase in an in-vitro model	3
Direct oral anticoagulants in patients with antiphospholipid syndrome: a retrospective study in a real-life patient cohort	3
Improved prevention of bleeding episodes with emicizumab in 3 patients with concomitant hemophilia A and von Willebrand disease	3
Multiple thrombotic sources and embolic events at arterial sites in a patient with protein-C deficiency	3
Efficacy of emicizumab therapy in two adult patients with type 3 von Willebrand disease	3
A refugee child with multiple patterned ecchymoses: a diagnostic dilemma between nonaccidental injury and primary hemostatic defect	3
The predictive role of platelet count for bleeding in patients with hepatitis B virus and hepatitis C virus infection	3
Never too soon to be thinking about heparin-induced thrombocytopenia! A case report of early onset heparin-induced thrombocytopenia	3
Resolution of cardiac surgical bleeding with the combination of 4-factor prothrombin complex concentrate and fresh frozen plasma following lack of response to fresh frozen plasma alone in a patient wi	3
Characteristics of factor V and protein C based on results from Korean testing centers	2
True vs. false immune-mediated thrombotic thrombocytopenic purpura exacerbations: a clinical case in the caplacizumab era	2
Dysfibrinogenemia: discrepant results following infusion of purified fibrinogen	2
Joint deficiency of coagulation factors VII and IX: a case report	2
A study of fibrinolytic system components in donor groups depending on various titers of circulating anti-SARS-CoV-2 IgG in the bloodstream	2

Characterization of thrombophilia-related plasmas evaluated by anticoagulants-mediated thrombin and plasmin generation assays	2
Pulmonary vein stump thrombosis after lung resection for lung cancer: clinical features and outcome	2
Compound heterozygous mutations (p.L68R∗37 and p.T241N) lead to abnormal protein levels and structures in hereditary FVII deficiency	2
A founder effect in hemophilia A patients from Russian Ural region with a new p.(His634Arg) variant in F8 gene	2
Severe bleeding diathesis as onset of light-chain amyloidosis: combined excessive fibrinolysis and acquired von Willebrand disease in a young patient	2
Addressing the haemophilia healthcare crisis amidst Taliban rule: a call to action	2
Hemophilia in the south of Tunisia	2
Severe thrombocytopenia associated to bevacizumab in a patient with scleroderma, gastrointestinal angiodysplasias and refractory gastrointestinal bleeding	2
Clot waveform analysis in acute promyelocytic leukemia	2
Lupus anticoagulant hypoprothrombinemia syndrome with multiple and high-titer antiphospholipid antibodies strongly interfered with coagulation assays	2
Real-world clinical outcomes with fostamatinib for the treatment of refractory chronic immune thrombocytopenia: a single-center experience	2
The effect of tranexamic acid on myocardial injury in cardiac surgical patients: a systematic review and meta-analysis	2
Reversal of life-threatening bleeding with protamine sulfate in a patient with plasma cell leukemia	2
Uvaol alleviates oxidative stress induced human umbilical vein endothelial cell injury by suppressing mitogen-activated protein kinase signaling pathway	2
New under the sun: ClotPro's ECA-test detects hyperfibrinolysis in a higher number of patients, more frequently and 9 min earlier	2
Screening hemostatic defects in Saudi University students with unexplained menorrhagia: a diagnosis, which could be missed	2
Self-limited thrombotic thrombocytopenic purpura	2
Comment on: coagulopathy following Crotaline snakebites in northeast Florida	2
Utility of the international society on thrombosis and hemostasis-bleeding assessment tool in the diagnosis of patients who suspected of platelet function disorders	2
Double jeopardy, glomangiopericytoma and Glanzmann thrombasthenia resulting in recurrent epistaxis: a case report	2
Diagnosis and treatment of coagulopathy using thromboelastography with platelet mapping is associated with decreased risk of pulmonary failure in COVID-19 patients	2
Identification of HLA alleles involved in immune thrombotic thrombocytopenic purpura patients from Turkey	2
Analysis of heparin-induced thrombocytopenia diagnostic and management strategies in individuals with inconclusive antibody optical densities	2
Clinical study reveals the efficacy of sirolimus in treating primary immune thrombocytopenia: findings from a single-center study	2
Inferior Vena Cava agenesis presenting as deep vein thrombosis in an eight year-old girl	2
Avatrombopag increased platelet count in a patient with chronic immune thrombocytopenia refractory to multiple lines of treatment	2
Clot waveform analysis in hemophilia carriers	2
Obesity and physical exercise in hemophilia	2
Pharmacokinetics, efficacy and safety of a novel fibrinogen concentrate in pediatric patients with congenital afibrinogenemia	2
The most common disease-causing mutation of factor XIII deficiency is corrected by CRISPR/CAS9 gene editing system	2