Current Opinion in Cell Biology

Article	Citations
The ATG conjugation systems in autophagy	262
Pay attention to membrane tension: Mechanobiology of the cell surface	114
Loop extrusion: theory meets single-molecule experiments	112
Novel roles of phosphoinositides in signaling, lipid transport, and disease	112
New insights into the regulation of apoptosis, necroptosis, and pyroptosis by receptor interacting protein kinase 1 and caspase-8	104
Receptor tyrosine kinase activation: From the ligand perspective	103
Caveolae: Formation, dynamics, and function	99
Causes and consequences of micronuclei	97
Advances in elucidating the function of leucine-rich repeat protein kinase-2 in normal cells and Parkinson's disease	92
The role of liquid–liquid phase separation in regulating enzyme activity	90
The role of the cell nucleus in mechanotransduction	81
The state of the septin cytoskeleton from assembly to function	80
The extracellular matrix viscoelasticity as a regulator of cell and tissue dynamics	78
Mechanics of the cellular actin cortex: From signalling to shape change	75
Fluid-like chromatin: Toward understanding the real chromatin organization present in the cell	73
Mitochondrial dynamics: Shaping and remodeling an organelle network	70
The cell pushes back: The Arp2/3 complex is a key orchestrator of cellular responses to environmental forces	66
Autophagosomes are formed at a distinct cellular structure	65
Tunneling nanotubes: Reshaping connectivity	64
New perspectives on integrin-dependent adhesions	64
Unconventional endocytic mechanisms	57
Macropinocytosis: Insights from immunology and cancer	56
FtsZ dynamics in bacterial division: What, how, and why?	55
Membrane supply and remodeling during autophagosome biogenesis	54
Caveolae: Mechanosensing and mechanotransduction devices linking membrane trafficking to mechanoadaptation	50

Advances in understanding molecular regulation of innate immune memory	49
Recent insight into intermediate filament structure	49
Mechanistic advances in axon pathfinding	49
Protein quality control in the endoplasmic reticulum	48
Recognising the signals for endosomal trafficking	48
Clathrin-independent endocytosis, retrograde trafficking, and cell polarity	46
Tracking and interpreting long-range chromatin interactions with super-resolution live-cell imaging	46
Three-dimensional chromatin in disease: What holds us together and what drives us apart?	45
Simulating realistic membrane shapes	44
Microtubule nucleation: The waltz between γ-tubulin ring complex and associated proteins	44
Chromatin and transcriptional regulation by reversible RNA methylation	43
Pluripotent stem cell models of early mammalian development	43
The multifaceted roles of microRNAs in differentiation	42
Epithelial-to-mesenchymal transition and different migration strategies as viewed from the neural crest	42
A mechanical perspective on phagocytic cup formation	42
Endosomal microdomains: Formation and function	41
Live-cell imaging in the era of too many microscopes	41
Dissecting the signaling pathways involved in the function of sperm flagellum	40
Inter-organelle lipid transfer: a channel model for Vps13 and chorein-N motif proteins	40
Jamming and arrest of cell motion in biological tissues	39
Karyopherins and condensates	39
Insulin stimulated GLUT4 translocation – Size is not everything!	39
Nuclear hubs built on RNAs and clustered organization of the genome	38
Xist drives spatial compartmentalization of DNA and protein to orchestrate initiation and maintenance of X inactivation	38
Filament formation by metabolic enzymes—A new twist on regulation	38
Reign in the membrane: How common lipids govern mitochondrial function	37
Progress in deciphering trophoblast cell differentiation during human placentation	37
A matter of time: Using dynamics and theory to uncover mechanisms of transcriptional bursting	36
A single-cell view of spermatogonial stem cells	36
Key phases in the formation of caveolae	36
Aligned forces: Origins and mechanisms of cancer dissemination guided by extracellular matrix architecture	35
Lamina-associated domains: Tethers and looseners	34
The dazzling rise of neurofilaments: Physiological functions and roles as biomarkers	34
Not all cancers are created equal: Tissue specificity in cancer genes and pathways	34
Microtubule self-repair	34
Biomolecular condensates in membrane receptor signaling	33
The Integrator complex at the crossroad of coding and noncoding RNA	33
Roles of PIKfyve in multiple cellular pathways	32
Endoplasmic reticulum–plasma membrane contacts: Principals of phosphoinositide and calcium signaling	31
Intermediate filaments as effectors of differentiation	31
On the choreography of genome folding: A grand pas de deux of cohesin and CTCF	31
CHMPions of repair: Emerging perspectives on sensing and repairing the nuclear envelope barrier	31
Regulation of nuclear actin dynamics in development and disease	30
Computational approaches from polymer physics to investigate chromatin folding	30
Regulating specificity in enhancer–promoter communication	30
ESCRT puts its thumb on the nanoscale: Fixing tiny holes in endolysosomes	29
Liquid-like interactions in heterochromatin: Implications for mechanism and regulation	29
Mechanobiology of neural development	29
Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease	29
Phosphorylation-dependent regulation of messenger RNA transcription, processing and translation within biomolecular condensates	29

How to maintain the genome in nuclear space	29
SMC complexes: Lifting the lid on loop extrusion	29
Ubiquitin-mediated regulation of sterol homeostasis	29
Neocortex expansion in development and evolution—from genes to progenitor cell biology	28
Design principles of tissue organisation: How single cells coordinate across scales	28
Interplay between membrane curvature and the actin cytoskeleton	28
Basement membrane remodeling guides cell migration and cell morphogenesis during development	28
Nuclear envelope remodelling during mitosis	28
Decoding mechanical cues by molecular mechanotransduction	28
Advanced models of human skeletal muscle differentiation, development and disease: Three-dimensional cultures, organoids and beyond	27
Organoid models for mammary gland dynamics and breast cancer	27
Cyclic dinucleotides at the forefront of innate immunity	27
Building consensus in neuromesodermal research: Current advances and future biomedical perspectives	27
Regulatory mechanisms governing chromatin organization and function	26
Lights, cytoskeleton, action: Optogenetic control of cell dynamics	26
Extensive GTPase crosstalk regulates Golgi trafficking and maturation	26
The emergence of genome architecture and zygotic genome activation	26
Mythical origins of the actin cytoskeleton	25
Clathrin’s life beyond 40: Connecting biochemistry with physiology and disease	25
Mechanically tuning actin filaments to modulate the action of actin-binding proteins	25
An amuse-bouche of stem cell regulation: Underlying principles and mechanisms from adult Drosophila intestinal stem cells	24
Oligodendrocyte progenitor cell fate and function in development and disease	24
The multifunctional nature of mitochondrial contact site proteins	24
How DNA loop extrusion mediated by cohesin enables V(D)J recombination	24
"The nuclear envelope, a meiotic jack-of-all-trades"	24
Control of mitosis, inflammation, and cell motility by limited leakage of lysosomes	24
Sending out molecules from the TGN	24
Higher-order assemblies in innate immune and inflammatory signaling: A general principle in cell biology	23
Dealing with DNA lesions: When one cell cycle is not enough	23
Intermediate filaments against actomyosin: the david and goliath of cell migration	23
Cell–cell contact and signaling in the muscle stem cell niche	23
Using optogenetics to tackle systems-level questions of multicellular morphogenesis	22
Nuclear fragility, blaming the blebs	22
Organelle distribution in neurons: Logistics behind polarized transport	22
Nuclear mechanotransduction in stem cells	21
Mitotic memories of gene activity	21
Circadian clock effects on cellular proliferation: Insights from theory and experiments	21
Advances into understanding metabolites as signaling molecules in cancer progression	21
Xist-mediated chromatin changes that establish silencing of an entire X chromosome in mammals	21
Nuclear deformations, from signaling to perturbation and damage	21
Biomolecular condensates in autophagy regulation	20
Functional organization of RNA polymerase II in nuclear subcompartments	20
Mechanisms of signalling-memory governing progression through the eukaryotic cell cycle	20
Regulation of nutrient transporters by metabolic and environmental stresses	20
Insights into gene regulation: From regulatory genomic elements to DNA-protein and protein-protein interactions	19
Asymmetric inheritance of epigenetic states in asymmetrically dividing stem cells	19
Forced to communicate: Integration of mechanical and biochemical signaling in morphogenesis	19
Epigenetic memory of cell fate commitment	18
From the inside out: Ion fluxes at the centre of endocytic traffic	18
Mechanosensing in embryogenesis	18
New directions for the clathrin adaptor AP-1 in cell biology and human disease	18
Positive feedback amplification in swarming immune cell populations	17
Mechanobiology of leader–follower dynamics in epithelial cell migration	17
The vesicle cluster as a major organizer of synaptic composition in the short-term and long-term	17
Cytoskeletal control of the secretory immune synapse	17
Advances in resolving the heterogeneity and dynamics of keratinocyte differentiation	17
From observing to controlling: Inducible control of organelle dynamics and interactions	17
Endocytic membrane trafficking in the control of centrosome function	17
Molecular architecture of enhancer–promoter interaction	17
Endoplasmic reticulum composition and form: Proteins in and out	17
Structural basis for GPCR signaling by small polar versus large lipid metabolites—discovery of non-metabolite ligands	17
Compartmentation and functions of sphingolipids	17
Environmental control of lineage plasticity and stem cell memory	16
Memorizing environmental signals through feedback and feedforward loops	16
Engineered ECM models: Opportunities to advance understanding of tumor heterogeneity	16
Variation on a theme: Evolutionary strategies for H2A.Z exchange by SWR1-type remodelers	16
Attach and stretch: Emerging roles for genome–lamina contacts in shaping the 3D genome	16
The cellular and signaling dynamics of salamander limb regeneration	16
From WRC to Arp2/3: Collective molecular mechanisms of branched actin network assembly	16
Early mechanical selection of cell extrusion and extrusion signaling in cancer	15
The intrinsic proteostasis network of stem cells	15
Roads and hubs of unconventional protein secretion	15
Mechanobiology in cortical waves and oscillations	15
Mechanisms of melanocyte polarity and differentiation: What can we learn from other neuroectoderm-derived lineages?	14
Mitochondrial movers and shapers: Recent insights into regulators of fission, fusion and transport	14
Signalling dynamics, cell decisions, and homeostatic control in health and disease	14
Mechanical plasticity in collective cell migration	13
Regulation of biomolecular condensate dynamics by signaling	13
Mechanisms of selective G protein–coupled receptor localization and trafficking	13
Interorganelle communication and membrane shaping in the early secretory pathway	13

Recent advances in the use of genetically encodable optical tools to elicit and monitor signaling events	13
Dissecting intercellular signaling with mass spectrometry–based proteomics	13
Spatiotemporal regulation of switching front–rear cell polarity	13
Diversity in cranial muscles: Origins and developmental programs	12
Cytoskeletal form and function in mammalian oocytes and zygotes	12
Coupling axonal mRNA transport and local translation to organelle maintenance and function	12
Collective behaviours in organoids	12
Self-organized protein patterns: The MinCDE and ParABS systems	12
Impact of the ‘tubulin economy’ on the formation and function of the microtubule cytoskeleton	12
Organogenesis in vitro	12
Transduction of cell and matrix geometric cues by the actin cytoskeleton	12
Seipin collaborates with the ER membrane to control the sites of lipid droplet formation	11
Imaging transcription elongation dynamics by new technologies unveils the organization of initiation and elongation in transcription factories	11
Ligand-induced degrons for studying nuclear functions	11
Biophysical forces in membrane bending and traffic	11
Principles of regeneration revealed by the planarian eye	11
Value of models for membrane budding	11
RNA gradients: Shapers of 3D genome architecture	11
Electrifying rhythms in plant cells	11
Protein quality control at the Golgi	11
Mechanical regulation of cell size, fate, and behavior during asymmetric cell division	10
From gut to glutes: The critical role of niche signals in the maintenance and renewal of adult stem cells	10
Cell memory of epithelial-mesenchymal plasticity in cancer	10
How stem cells remember their past	10
Advances in defining signaling networks for the establishment of neuronal polarity	10
Integrating cellular dimensions with cell differentiation during early development	9
Multiscale modelling of chromatin organisation: Resolving nucleosomes at near-atomistic resolution inside genes	9
Mnemons and the memorization of past signaling events	9
Biomolecular condensates in epithelial junctions	9
The compass to follow: Focal adhesion turnover	9
Nucleocytoplasmic partitioning as a mechanism to regulate Arabidopsis signaling events	9
Emerging mechanisms and dynamics of three-dimensional genome organisation at zygotic genome activation	9
Intravital microscopy to illuminate cell state plasticity during metastasis	9
Single nucleosome tracking to study chromatin plasticity	9
Evolution and diversification of mitochondrial protein import systems	9
Emergent properties of mitotic chromosomes	9
Find your coat: Using correlative light and electron microscopy to study intracellular protein coats	9
Multiscale morphogenesis of the mouse blastocyst by actomyosin contractility	9
Regulation and physiology of membrane contact sites	9
A kinetic view of clathrin assembly and endocytic cargo sorting	8
Building the phagocytic cup on an actin scaffold	8
Development of a multiciliated cell	8
“Make way”: Pathogen exploitation of membrane traffic	8
Evolving methodologies and concepts in 4D nucleome research	8
Cadherins and the cortex: A matter of time?	8
Under pressure: Stem cell–niche interactions coordinate tissue adaptation to inflammation	8
Don't forget to be picky – selective autophagy of protein aggregates in neurodegenerative diseases	8
New insights into tuft cell formation: Implications for structure–function relationships	8
Unconventional roles for membrane traffic proteins in response to muscle membrane stress	8
Interplay between caspase, Yes-associated protein, and mechanics: A possible switch between life and death?	8
Cellularization across eukaryotes: Conserved mechanisms and novel strategies	8
Signaling oscillations: Molecular mechanisms and functional roles	7
Roles for microtubules in the proliferative and differentiated cells of stratified epithelia	7
Stand by me: Fibroblasts regulation of the intestinal epithelium during development and homeostasis	7
Moving beyond disease to function: Physiological roles for polyglutamine-rich sequences in cell decisions	7
Physiological and regulatory convergence between osmotic and nutrient stress responses in microbes	7
Mechanisms of cell specification and differentiation in vertebrate cranial sensory systems	7
Plasticity in centromere organization and kinetochore composition: Lessons from diversity	7
Intracellular niche switching as host subversion strategy of bacterial pathogens	7
ER and Golgi trafficking in axons, dendrites, and glial processes	7
Going your own way: Self-guidance mechanisms in cell migration	7
Versatile roles for histones in early development	7
Encoding and decoding NF-κB nuclear dynamics	7
Quantifying and visualising the nuances of cellular dynamics in vivo using intravital imaging	7
Cellular mechanosignaling for sensing and transducing matrix rigidity	7
Shaping up: Recent advances in the study of plant calcium channels	6
Mechanosignalling pathways that regulate endothelial barrier function	6
Myosin motors in sensory hair bundle assembly	6
You can go your own way: SNX-BAR coat complexes direct traffic at late endosomes	6
The nature of the root clock at single cell resolution: Principles of communication and similarities with plant and animal pulsatile and circadian mechanisms	6
Signal integration in forward and reverse neutrophil migration: Fundamentals and emerging mechanisms	6
Sculpting the heart: Cellular mechanisms shaping valves and trabeculae	6
Biophysics of endocytic vesicle formation: A focus on liquid–liquid phase separation	6
Cell competition controls differentiation in mouse embryos and stem cells	6
Protein self-assembly: A new frontier in cell signaling	6
Fidelity of organellar protein targeting	6