Current Opinion in Cell Biology

Article	Citations
Causes and consequences of micronuclei	134
The role of liquid–liquid phase separation in regulating enzyme activity	115
The state of the septin cytoskeleton from assembly to function	94
The extracellular matrix viscoelasticity as a regulator of cell and tissue dynamics	94
Tunneling nanotubes: Reshaping connectivity	89
Mitochondrial dynamics: Shaping and remodeling an organelle network	84
The cell pushes back: The Arp2/3 complex is a key orchestrator of cellular responses to environmental forces	74
FtsZ dynamics in bacterial division: What, how, and why?	73
Unconventional endocytic mechanisms	64
Membrane supply and remodeling during autophagosome biogenesis	63
Recent insight into intermediate filament structure	61
Caveolae: Mechanosensing and mechanotransduction devices linking membrane trafficking to mechanoadaptation	60
Tracking and interpreting long-range chromatin interactions with super-resolution live-cell imaging	56
A matter of time: Using dynamics and theory to uncover mechanisms of transcriptional bursting	56
Microtubule nucleation: The waltz between γ-tubulin ring complex and associated proteins	54
The multifaceted roles of microRNAs in differentiation	53
Simulating realistic membrane shapes	51
Jamming and arrest of cell motion in biological tissues	49
Chromatin and transcriptional regulation by reversible RNA methylation	48
Roles of PIKfyve in multiple cellular pathways	46
Progress in deciphering trophoblast cell differentiation during human placentation	46
The dazzling rise of neurofilaments: Physiological functions and roles as biomarkers	44
A single-cell view of spermatogonial stem cells	44
Aligned forces: Origins and mechanisms of cancer dissemination guided by extracellular matrix architecture	43
The Integrator complex at the crossroad of coding and noncoding RNA	40

Biomolecular condensates in membrane receptor signaling	40
On the choreography of genome folding: A grand pas de deux of cohesin and CTCF	40
Lamina-associated domains: Tethers and looseners	39
Key phases in the formation of caveolae	39
Basement membrane remodeling guides cell migration and cell morphogenesis during development	38
Intermediate filaments as effectors of differentiation	38
Microtubule self-repair	38
SMC complexes: Lifting the lid on loop extrusion	38
Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease	37
Regulating specificity in enhancer–promoter communication	36
Nuclear envelope remodelling during mitosis	35
Advanced models of human skeletal muscle differentiation, development and disease: Three-dimensional cultures, organoids and beyond	34
Building consensus in neuromesodermal research: Current advances and future biomedical perspectives	34
Interplay between membrane curvature and the actin cytoskeleton	34
Sending out molecules from the TGN	32
Neocortex expansion in development and evolution—from genes to progenitor cell biology	32
Design principles of tissue organisation: How single cells coordinate across scales	32
Cell–cell contact and signaling in the muscle stem cell niche	31
Phosphorylation-dependent regulation of messenger RNA transcription, processing and translation within biomolecular condensates	31
Decoding mechanical cues by molecular mechanotransduction	31
Nuclear fragility, blaming the blebs	31
Mechanically tuning actin filaments to modulate the action of actin-binding proteins	31
Oligodendrocyte progenitor cell fate and function in development and disease	30
Functional organization of RNA polymerase II in nuclear subcompartments	28
Molecular architecture of enhancer–promoter interaction	28
An amuse-bouche of stem cell regulation: Underlying principles and mechanisms from adult Drosophila intestinal stem cells	27
Mitotic memories of gene activity	27
Xist-mediated chromatin changes that establish silencing of an entire X chromosome in mammals	27
Control of mitosis, inflammation, and cell motility by limited leakage of lysosomes	27
Regulatory mechanisms governing chromatin organization and function	26
Asymmetric inheritance of epigenetic states in asymmetrically dividing stem cells	26
Mythical origins of the actin cytoskeleton	26
How DNA loop extrusion mediated by cohesin enables V(D)J recombination	26
New directions for the clathrin adaptor AP-1 in cell biology and human disease	26
Nuclear deformations, from signaling to perturbation and damage	25
Mechanosensing in embryogenesis	25
Epigenetic memory of cell fate commitment	25
Insights into gene regulation: From regulatory genomic elements to DNA-protein and protein-protein interactions	24
The cellular and signaling dynamics of salamander limb regeneration	24
Biomolecular condensates in autophagy regulation	24
Organelle distribution in neurons: Logistics behind polarized transport	24
Mitochondrial movers and shapers: Recent insights into regulators of fission, fusion and transport	23
Circadian clock effects on cellular proliferation: Insights from theory and experiments	23
Mechanisms of signalling-memory governing progression through the eukaryotic cell cycle	23
Dealing with DNA lesions: When one cell cycle is not enough	23
Interorganelle communication and membrane shaping in the early secretory pathway	23
Mechanobiology in cortical waves and oscillations	22
From WRC to Arp2/3: Collective molecular mechanisms of branched actin network assembly	22
Cytoskeletal control of the secretory immune synapse	22
Endoplasmic reticulum composition and form: Proteins in and out	21

Variation on a theme: Evolutionary strategies for H2A.Z exchange by SWR1-type remodelers	21
From the inside out: Ion fluxes at the centre of endocytic traffic	21
Compartmentation and functions of sphingolipids	21
Regulation of biomolecular condensate dynamics by signaling	21
Advances in resolving the heterogeneity and dynamics of keratinocyte differentiation	21
Signalling dynamics, cell decisions, and homeostatic control in health and disease	21
Roads and hubs of unconventional protein secretion	21
Attach and stretch: Emerging roles for genome–lamina contacts in shaping the 3D genome	20
From observing to controlling: Inducible control of organelle dynamics and interactions	20
The vesicle cluster as a major organizer of synaptic composition in the short-term and long-term	19
Positive feedback amplification in swarming immune cell populations	19
Engineered ECM models: Opportunities to advance understanding of tumor heterogeneity	19
Mechanisms of selective G protein–coupled receptor localization and trafficking	19
Impact of the ‘tubulin economy’ on the formation and function of the microtubule cytoskeleton	19
Ligand-induced degrons for studying nuclear functions	18
Memorizing environmental signals through feedback and feedforward loops	18
Spatiotemporal regulation of switching front–rear cell polarity	18
Environmental control of lineage plasticity and stem cell memory	18
Coupling axonal mRNA transport and local translation to organelle maintenance and function	18
Mechanisms of melanocyte polarity and differentiation: What can we learn from other neuroectoderm-derived lineages?	17
The intrinsic proteostasis network of stem cells	17
Protein quality control at the Golgi	16
The DNA damage response in the chromatin context: A coordinated process	15
Seipin collaborates with the ER membrane to control the sites of lipid droplet formation	15
Myosin motors in sensory hair bundle assembly	15
Transduction of cell and matrix geometric cues by the actin cytoskeleton	15
RNA gradients: Shapers of 3D genome architecture	15
The compass to follow: Focal adhesion turnover	15
You can go your own way: SNX-BAR coat complexes direct traffic at late endosomes	15
Early mechanical selection of cell extrusion and extrusion signaling in cancer	15
Self-organized protein patterns: The MinCDE and ParABS systems	15
Mechanical regulation of cell size, fate, and behavior during asymmetric cell division	14
Principles of regeneration revealed by the planarian eye	14
Sculpting the heart: Cellular mechanisms shaping valves and trabeculae	14
Who's really in charge: Diverse follower cell behaviors in collective cell migration	14
Mechanical plasticity in collective cell migration	14
Multiscale modelling of chromatin organisation: Resolving nucleosomes at near-atomistic resolution inside genes	14
How stem cells remember their past	14
Diversity in cranial muscles: Origins and developmental programs	14
Collective behaviours in organoids	14
Electrifying rhythms in plant cells	13
Building the phagocytic cup on an actin scaffold	13
Cellularization across eukaryotes: Conserved mechanisms and novel strategies	13
Plasticity in centromere organization and kinetochore composition: Lessons from diversity	13
Evolution and diversification of mitochondrial protein import systems	13
A kinetic view of clathrin assembly and endocytic cargo sorting	13
Regulation and physiology of membrane contact sites	13
Live-cell imaging in the deep learning era	13
The machinery of vesicle fusion	12
Intracellular niche switching as host subversion strategy of bacterial pathogens	12
Organogenesis in vitro	12
Cellular mechanosignaling for sensing and transducing matrix rigidity	12
Integrating cellular dimensions with cell differentiation during early development	12
Cytoskeletal form and function in mammalian oocytes and zygotes	12
Imaging transcription elongation dynamics by new technologies unveils the organization of initiation and elongation in transcription factories	12
Value of models for membrane budding	12
PI4KA and PIKfyve: Essential phosphoinositide signaling enzymes involved in myriad human diseases	11
Nucleocytoplasmic partitioning as a mechanism to regulate Arabidopsis signaling events	11
ER and Golgi trafficking in axons, dendrites, and glial processes	11
Insights into the role of the membranes in Rab GTPase regulation	11
Single nucleosome tracking to study chromatin plasticity	11
Cell memory of epithelial-mesenchymal plasticity in cancer	11
Don't forget to be picky – selective autophagy of protein aggregates in neurodegenerative diseases	11
Physiological and regulatory convergence between osmotic and nutrient stress responses in microbes	11
Phosphatidylserine transport in cell life and death	11
Emerging mechanisms and dynamics of three-dimensional genome organisation at zygotic genome activation	11
The (social) lives, deaths, and biophysical phases of lipid droplets	10
Biomolecular condensates in epithelial junctions	10
Signaling oscillations: Molecular mechanisms and functional roles	10
Encoding and decoding NF-κB nuclear dynamics	10
Sperm chromatin structure: Insights from in vitro to in situ experiments	10
The unique biomechanics of intermediate filaments – From single filaments to cells and tissues	10
Endosome biogenesis is controlled by ER and the cytoskeleton at tripartite junctions	9
Mnemons and the memorization of past signaling events	9
Cell competition controls differentiation in mouse embryos and stem cells	9
Development of a multiciliated cell	9
New insights into tuft cell formation: Implications for structure–function relationships	9
Intravital microscopy to illuminate cell state plasticity during metastasis	9
Stand by me: Fibroblasts regulation of the intestinal epithelium during development and homeostasis	9
Find your coat: Using correlative light and electron microscopy to study intracellular protein coats	9

Versatile roles for histones in early development	9
Roles for microtubules in the proliferative and differentiated cells of stratified epithelia	9
Under pressure: Stem cell–niche interactions coordinate tissue adaptation to inflammation	9
Cadherins and the cortex: A matter of time?	8
Biophysics of endocytic vesicle formation: A focus on liquid–liquid phase separation	8
New insights into the OSBP‒VAP cycle	8
Notch-mediated cellular interactions between vascular cells	8
Mechanosignalling pathways that regulate endothelial barrier function	8
Interplay between caspase, Yes-associated protein, and mechanics: A possible switch between life and death?	8
Fidelity of organellar protein targeting	8
Regulatory events controlling ER-phagy	8
Going your own way: Self-guidance mechanisms in cell migration	8
The redox-responsive roles of intermediate filaments in cellular stress detection, integration and mitigation	8
Protein self-assembly: A new frontier in cell signaling	8
Quantifying and visualising the nuances of cellular dynamics in vivo using intravital imaging	8
Mechanisms of cell specification and differentiation in vertebrate cranial sensory systems	8
Shaping up: Recent advances in the study of plant calcium channels	8
How do disordered head domains assist in the assembly of intermediate filaments?	8
Manipulation of epithelial cell architecture by the bacterial pathogens Listeria and Shigella	7
Emerging cell biological functions of phosphatidylinositol 5 phosphate 4 kinase	7
Beyond SAHF: An integrative view of chromatin compartmentalization during senescence	7
How to wrinkle a cell: Emerging mechanisms of microridge morphogenesis	7
Microglial ‘fat shaming’ in development and disease	7
Stretching the limits of extracellular signal-related kinase (ERK) signaling — Cell mechanosensing to ERK activation	7
Mining cell–cell signaling in single-cell transcriptomics atlases	7
Actin nucleoskeleton in embryonic development and cellular differentiation	7
The nature of the root clock at single cell resolution: Principles of communication and similarities with plant and animal pulsatile and circadian mechanisms	7
Signal integration in forward and reverse neutrophil migration: Fundamentals and emerging mechanisms	7
Moving beyond disease to function: Physiological roles for polyglutamine-rich sequences in cell decisions	7
Computational modeling of membrane trafficking processes: From large molecular assemblies to chemical specificity	6
Building and breaking mechanical bridges between the nucleus and cytoskeleton: Regulation of LINC complex assembly and disassembly	6
The dynamic nuclear envelope: resilience in health and dysfunction in disease	6
Methods for mapping 3D-chromosome architecture around nucleoli	6
Microtubule control of migration: Coordination in confinement	6
Extracellular matrix dynamics: A key regulator of cell migration across length-scales and systems	6
Novel roles for cooperating collagen receptor families in fibrotic niches	6
Plasmalemmal interface for calcium signaling in osteoclast differentiation	6
Migration cues interpretation by clathrin-coated structures	6
Dynamic links between mechanical forces and metabolism shape the tumor milieu	6
Breaking the barrier: In vitro models to study choroid plexus development	6
Deciphering the chromatin organization and dynamics for muscle stem cell function	6
Early steps in the birth of four membrane-bound organelles—Peroxisomes, lipid droplets, lipoproteins, and autophagosomes	6
Roles of ESCRT-III polymers in cell division across the tree of life	6
Receptors, enzymes and self-attraction as autocrine generators and amplifiers of chemotaxis and cell steering	6
Lipid nanodomains and receptor signaling: From actin-based organization to membrane mechanics	6
Diversification of chromatin organization in eukaryotes	5
The many faces of the bouquet centrosome MTOC in meiosis and germ cell development	5
Forced back into shape: Mechanics of epithelial wound repair	5
Exploring membrane mechanics: The role of membrane-cortex attachment in cell dynamics	5
Autoinhibition and activation of kinesin-1 and their involvement in amyotrophic lateral sclerosis	5
Myosins and membrane trafficking in intestinal brush border assembly	5
Mechanotransduction: Forcing a change in metabolism	5
The Sky's the LEMit: New insights into nuclear structure regulation of transcription factor activity	5
Jagged-mediated development and disease: Mechanistic insights and therapeutic implications for Alagille syndrome	5
Growth across scales: Dynamic signaling impacts tissue size and shape	5
Growing thin — How bulk lipid transport drives expansion of the autophagosome membrane but not of its lumen	5
The reversibility of cellular mechano-activation	5
Macromolecular crowding: Sensing without a sensor	5
Genome folding and refolding in differentiation and cellular senescence	5
Lamins: The backbone of the nucleocytoskeleton interface	4
Molecular and cellular constraints on vesicle traffic evolution	4
Creative processes during vertebrate organ morphogenesis: Biophysical self-organization at the supracellular scale	4
Sperm-specific proteins: new implications for diagnostic development and cancer immunotherapy	4
Building the brush border, one microvillus at a time	4
Reading oscillatory instructions: How cells achieve time-dependent responses to oscillating transcription factors	4
Techniques for and challenges in reconstructing 3D genome structures from 2D chromosome conformation capture data	4
Highly conserved, but highly specific: Somatic cell–cell fusion in filamentous fungi	4
Genome organization: Tag it, move it, place it	4
Disturbed endothelial cell signaling in tumor progression and therapy resistance	4
Cell cycle control by cell-matrix interactions	4
Dynamic asymmetry and why chromatin defies simple physical definitions	4
Protein control of membrane and organelle dynamics: Insights from the divergent eukaryote Toxoplasma gondii	4
The molecular architecture of the ciliary transition zones	4
The role of cellular active stresses in shaping the zebrafish body axis	4
The principles of cellular geometry scaling	4
Mechanical regulation of the Notch signaling pathway	4
The ubiquitous nanocluster: A molecular scale organizing principle that governs cellular information flow	4
Intermediate, but not average: The unusual lives of the nuclear lamin proteins	4
Cytoskeletal symmetry breaking in animal cells	4
“Gearing” up for dynamin-catalyzed membrane fission	4