Clinical and Experimental Allergy

Article	Citations
Polyethylene glycol (PEG) is a cause of anaphylaxis to the Pfizer/BioNTech mRNA COVID‐19 vaccine	173
Incidence and risk factors for persistent symptoms in adults previously hospitalized for COVID‐19	102
Effectiveness and safety of dupilumab for the treatment of severe asthma in a real‐life French multi‐centre adult cohort	77
Dupilumab suppresses type 2 inflammatory biomarkers across multiple atopic, allergic diseases	72
Expression of ACE2 in airways: Implication for COVID‐19 risk and disease management in patients with chronic inflammatory respiratory diseases	61
Clinical manifestations and impact on daily life of allergy to polyethylene glycol (PEG) in ten patients	54
Real‐world experience with mepolizumab: Does it deliver what it has promised?	53
Real‐life evaluation of mepolizumab efficacy in patients with severe eosinophilic asthma, according to atopic trait and allergic phenotype	51
Benralizumab effect on severe chronic rhinosinusitis with nasal polyps (CRSwNP): A randomized double‐blind placebo‐controlled trial	48
Omalizumab in the treatment of adult patients with mastocytosis: A systematic review	47
The use of biologics in food allergy	46
The epidemiology of eczema in children and adults in England: A population‐based study using primary care data	44
Interleukin‐17 is a potential player and treatment target in severe chronic spontaneous urticaria	42
Mechanisms of oral immunotherapy	38
Paediatric and adolescent asthma: A narrative review of telemedicine and emerging technologies for the post‐COVID‐19 era	37
Staphylococcus aureus enterotoxin B disrupts nasal epithelial barrier integrity	36
Skincare interventions in infants for preventing eczema and food allergy: A cochrane systematic review and individual participant data meta‐analysis	35
Real‐world efficacy of treatment with benralizumab, dupilumab, mepolizumab and reslizumab for severe asthma: A systematic review and meta‐analysis	32
The association between COVID‐19 and asthma: A systematic review and meta‐analysis	32
Antihistamine‐resistant chronic spontaneous urticaria remains undertreated: 2‐year data from the AWARE study	31
BSACI 2021 guideline for the management of egg allergy	31
The airway fungal microbiome in asthma	30
Digital health interventions in children with asthma	30
A randomized, placebo‐controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER)	29
APPEAL‐2: A pan‐European qualitative study to explore the burden of peanut‐allergic children, teenagers and their caregivers	29

Adverse reactions to COVID‐19 vaccines: A practical approach	27
Overlap of allergic, eosinophilic and type 2 inflammatory subtypes in moderate‐to‐severe asthma	27
Frequency of guideline‐defined cow's milk allergy symptoms in infants: Secondary analysis of EAT trial data	27
Clinical evaluation of type 2 disease status in a real‐world population of difficult to manage asthma using historic electronic healthcare records of blood eosinophil counts	27
Treatment effectiveness for Vocal Cord Dysfunction in adults and adolescents: A systematic review	27
Treating severe asthma: Targeting the IL‐5 pathway	27
Association between childhood asthma and attention deficit hyperactivity or autism spectrum disorders: A systematic review with meta‐analysis	26
The Polysorbate containing AstraZeneca COVID‐19 vaccine is tolerated by polyethylene glycol (PEG) allergic patients	26
Characterization of a 7 kDa pollen allergen belonging to the gibberellin‐regulated protein family from three Cupressaceae species	25
BSACIguideline for the set‐up of penicillin allergy de‐labelling services by non‐allergists working in a hospital setting	24
Pea (Pisum sativum) allergy in children: Pis s 1 is an immunodominant major pea allergen and presents IgE binding sites with potential diagnostic value	24
An anti‐siglec‐8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells	23
Switching between biologics in severe asthma patients. When the first choice is not proven to be the best	23
Revisiting Asian chronic rhinosinusitis in the era of type 2 biologics	23
Real‐world Omalizumab and Mepolizumab treated difficult asthma phenotypes and their clinical outcomes	22
Fungal sensitization and positive fungal culture from sputum in children with asthma are associated with reduced lung function and acute asthma attacks respectively	21
Repetitive nasal allergen challenge in allergic rhinitis: Priming and Th2‐type inflammation but no evidence of remodelling	21
Allergen labelling: Current practice and improvement from a communication perspective	20
Quercus ilex pollen allergen, Que i 1, responsible for pollen food allergy syndrome caused by fruits in Spanish allergic patients	20
Peanut allergy impact on productivity and quality of life (PAPRIQUA): Caregiver‐reported psychosocial impact of peanut allergy on children	20
Mast cell activation tests by flow cytometry: A new diagnostic asset?	19
Poor understanding of allergen labelling by allergic and non‐allergic consumers	19
MRGPRX2 activation in mast cells by neuromuscular blocking agents and other agonists: Modulation by sugammadex	19
Sex‐specific associations of asthma acquisition with changes in DNA methylation during adolescence	19
Trends in use of specialized formula for managing cow's milk allergy in young children	19
Personalized prediction of daily eczema severity scores using a mechanistic machine learning model	19
Asthma and fixed airflow obstruction: Long‐term trajectories suggest distinct endotypes	19
Anaphylaxis Refractory to intramuscular adrenaline during in‐hospital food challenges: A case series and proposed management	19
Tree pollen exposure is associated with reduced lung function in children	18
Neutrophilic asthma features increased airway classical monocytes	18
Efficacy and safety of hydrolyzed formulas for cow's milk allergy management: A systematic review of randomized controlled trials	18
Sputum microRNA‐screening reveals Prostaglandin EP3 receptor as selective target in allergen‐specific immunotherapy	18
Role of autophagy in regulating interleukin‐10 and the responses to corticosteroids and statins in asthma	18
Effectiveness of benralizumab in severe eosinophilic asthma: Distinct sub‐phenotypes of response identified by cluster analysis	18
Fruit, vegetable and dietary antioxidant intake in school age, respiratory health up to young adulthood	17
BSACIguideline for the diagnosis and management of pollen food syndrome in theUK	17
Immune‐microbiota interaction in Finnish and Russian Karelia young people with high and low allergy prevalence	17
Fungal sensitization and its relationship to mepolizumab response in patients with severe eosinophilic asthma	16
Vitamin A deficiency exacerbates extrinsic atopic dermatitis development by potentiating type 2 helper T cell‐type inflammation and mast cell activation	16
GSTO1‐1 is an upstream suppressor of M2 macrophage skewing and HIF‐1α‐induced eosinophilic airway inflammation	16
Sensitization to peanut, egg or pets is associated with skin barrier dysfunction in children with atopic dermatitis	16
Human β‐defensin‐2 suppresses key features of asthma in murine models of allergic airways disease	16
Investigating the causal relationship between allergic disease and mental health	16
Benralizumab strongly reduces blood basophils in severe eosinophilic asthma	16
Matching‐adjusted comparison of oral corticosteroid reduction in asthma: Systematic review of biologics	16
Regulation of oral antigen delivery early in life: Implications for oral tolerance and food allergy	16
Gene signatures from scRNA‐seq accurately quantify mast cells in biopsies in asthma	16
The effect of water hardness on atopic eczema, skin barrier function: A systematic review, meta‐analysis	15
Bidirectional association between alopecia areata and atopic dermatitis: A population‐based cohort study in Taiwan	15
A qualitative and quantitative comparison of IgE antibody profiles with two multiplex platforms for component‐resolved diagnostics in allergic patients	15

Molecular approaches to allergen‐specific immunotherapy: Are we so far from clinical implementation?	15
Assessment of adherence to corticosteroids in asthma by drug monitoring or fractional exhaled nitric oxide: A literature review	15
The effects of increasing fruit and vegetable intake in children with asthma: A randomized controlled trial	15
Transcriptomics of biopsies identifies novel genes and pathways linked to neutrophilic inflammation in severe asthma	15
Decrease in CD38+ TH2A cell frequencies following immunotherapy with house dust mite tablet correlates with humoral responses	15
Patterns and trends in eczema management in UK primary care (2009–2018): A population‐based cohort study	15
A polygenic risk score for asthma in a large racially diverse population	15
Randomized controlled trial of triple versus dual inhaler therapy on small airways in smoking asthmatics	15
Relationship of sputum mast cells with clinical and inflammatory characteristics of asthma	15
Efficacy of transdermal immunotherapy with biodegradable microneedle patches in a murine asthma model	15
Association between biomarkers and house dust mite sublingual immunotherapy in allergic asthma	14
Peptide allergen‐specific immunotherapy for allergic airway diseases—State of the art	14
Cow’s milk allergy prevention and treatment by heat‐treated whey—A study in Brown Norway rats	14
Triggers of breathlessness in inducible laryngeal obstruction and asthma	14
Obesity influences the outcomes of anti‐IgE (omalizumab) therapy of asthma	14
Hypotheses to explain the associations between asthma and the consequences of COVID‐19 infection	14
Omalizumab in chronic inducible urticaria: A real‐life study of efficacy, safety, predictors of treatment outcome and time to response	14
Pharmacokinetics of adrenaline autoinjectors	14
A virtual management approach to infant egg allergy developed in response to pandemic‐imposed restrictions	14
@IT2020: An innovative algorithm for allergen immunotherapy prescription in seasonal allergic rhinitis	14
Micronutritional supplementation with a holoBLG‐based FSMP (food for special medical purposes)‐lozenge alleviates allergic symptoms in BALB/c mice: Imitating the protective farm effect	14
Caesarean delivery and the risk of atopic dermatitis in children	14
Innate IFN‐lambda responses to dsRNA in the human infant airway epithelium and clinical regulatory factors during viral respiratory infections in early life	13
The Asian wasp Vespa velutina nigrithorax: Entomological and allergological characteristics	13
Evidence for causal associations between prenatal and postnatal antibiotic exposure and asthma in children, England	13
Outdoor pollen‐related changes in lung function and markers of airway inflammation: A systematic review and meta‐analysis	13
Impaired small airway function in non‐asthmatic chronic rhinosinusitis with nasal polyps	13
Lipid transfer protein allergy: A review of current controversies	12
Tryptase release does not discriminate between IgE‐ and MRGPRX2‐mediated activation in human mast cells	12
An algorithm for safe de‐labelling of antibiotic allergy in adult hospital in‐patients	12
Trends in eczema prevalence in children and adolescents: A Global Asthma Network Phase I Study	12
INEXAS: A Phase 2 Randomized Trial of On‐demand Inhaled Interferon Beta‐1a in Severe Asthmatics	12
The evolving landscape of biologic therapies for atopic dermatitis: Present and future perspective	12
Clinical and immunological data from chronic urticaria onset after mRNA SARS‐CoV‐2 vaccines	12
Detection of specific IgE against linear epitopes from Gal d 1 has additional value in diagnosing hen’s egg allergy in adults	12
Intralymphatic immunotherapy with one or two allergens renders similar clinical response in patients with allergic rhinitis due to birch and grass pollen	12
Possible association between early formula and reduced risk of cow’s milk allergy: The Japan Environment and Children’s Study	12
Allergenicity at component level of sub‐pollen particles from different sources obtained by osmolar shock: A molecular approach to thunderstorm‐related asthma outbreaks	12
Multimorbidity in asthma, association with allergy, inflammatory markers and symptom burden, results from the Swedish GA2LEN study	12
Alpha‐gal syndrome: An emerging cause of food and drug allergy	12
Cyclophilin – A novel cross‐reactive determinant in peanut	11
Eosinophilic esophagitis: Immune mechanisms and therapeutic targets	11
Airway gene expression identifies subtypes of type 2 inflammation in severe asthma	11
Prevalence and early‐life risk factors for tree nut sensitization and allergy in young adults	11
Ocular surface disease is common in moderate‐to‐severe atopic dermatitis patients	11
Burden of allergic disease among ethnic minority groups in high‐income countries	11
Pharmacogenetics of inhaled corticosteroids and exacerbation risk in adults with asthma	11
Identification, characterization and epitope mapping of proteins encoded by putative allergenic napin genes from Brassica rapa	11
Diagnosis of Ibuprofen allergy through oral challenge	11
Early‐life predictors and risk factors of peanut allergy, and its association with asthma in later‐life: Population‐based birth cohort study	11
How do biologicals and other novel therapies effect clinically used biomarkers in severe asthma?	11
Exogenous factors in the pathogenesis of atopic dermatitis: Irritants and cutaneous infections	11
COVID‐19 as a trigger of acute attacks in people with hereditary angioedema	11
Efficacy of inhaled salbutamol with and without prednisolone for first acute rhinovirus‐induced wheezing episode	11
A hybrid of two major Blomia tropicalis allergens as an allergy vaccine candidate	11
National Survey of United Kingdom Paediatric Allergy Services	11
Mepolizumab decreases tissue eosinophils while increasing type‐2 cytokines in eosinophilic chronic rhinosinusitis	10
Simplified AIT for allergy to several tree pollens—Arguments from the immune outcome analyses following treatment with SQ tree SLIT‐tablet	10
Characterization of anaphylaxis reveals different metabolic changes depending on severity and triggers	10
Information needs of patients considering oral immunotherapy for food allergy	10
Asthma did not increase in‐hospital COVID‐19‐related mortality in a tertiary UK hospital	10
Identifying key priorities for research to protect the consumer with food hypersensitivity: A UK Food Standards Agency Priority Setting Exercise	10
High proportion of inflammatory CD62Llow eosinophils in blood and nasal polyps of severe asthma patients	10
Circulating Ara h 6 as a marker of peanut protein absorption in tolerant and allergic humans following ingestion of peanut‐containing foods	10
Inhibition of cow’s milk allergy development in mice by oral delivery of β‐lactoglobulin‐derived peptides loaded PLGA nanoparticles is associated with systemic whey‐specific immune silencing	10
Second‐hand smoke and NFE2L2 genotype interaction increases paediatric asthma risk and severity	10
Peanuts in the air ‐ clinical and experimental studies	10
Effect of Acinetobacter lwoffii on the modulation of macrophage activation and asthmatic inflammation	10
Null association between serum 25‐hydroxyvitamin D levels with allergic rhinitis, allergic sensitization and non‐allergic rhinitis: A Mendelian randomization study	10
Respiratory health in professional cleaners: Symptoms, lung function, and risk factors	10
Allergic diseases in India – Prevalence, risk factors and current challenges	10
Detection and management of milk allergy: Delphi consensus study	10
Practical management of suspected hypersensitivity reactions to anti‐tuberculosis drugs	10
Advanced glycation end product intake during pregnancy and offspring allergy outcomes: A Prospective cohort study	10
Population prevalence of allergic bronchopulmonary aspergillosis in asthma: An epidemiological study of 43,261 participants from North India	10
Atopic dermatitis trajectories to age 8 years in the GUSTO cohort	10
IgE‐mediated allergy to polyethylene glycol (PEG) as a cause of anaphylaxis to mRNA COVID‐19 vaccines	10
Substance P‐induced lung inflammation in mice is mast cell dependent	10
'Diagnosing food protein‐induced enterocolitis syndrome'	10
Genetic impact of CDHR3 on the adult onset of asthma and COPD	9

Efficacy of an oral CRTH2 antagonist (AZD1981) in the treatment of chronic rhinosinusitis with nasal polyps in adults: A randomized controlled clinical trial	9
Altered immune cell profiles and impaired CD4 T‐cell activation in single and multi‐food allergic adolescents	9
The impact of childhood asthma on academic performance: A matched population‐based cohort study	9
Increased IL‐6 and Potential IL‐6 trans‐signalling in the airways after an allergen challenge	9
ImmunoCAP ISAC in food allergy diagnosis: a systematic review of diagnostic test accuracy	9
Palforzia for peanut allergy: Panacea or predicament	9
Allergic disease prevalence in school children in Bengaluru, India: A cross‐sectional survey	9
The relationship between human coronaviruses, asthma and allergy—An unresolved dilemma	9
Immunotherapy with Vespula venom for Vespa velutina nigrithorax anaphylaxis: Preliminary clinical and immunological results	9
Whole blood transcriptional variations between responders and non‐responders in asthma patients receiving omalizumab	9
Mast cell activation test: A new asset in the investigation of the chlorhexidine cross‐sensitization profile	9
Epigenetic methylation in Eosinophilic Esophagitis: Molecular ageing and novel biomarkers for treatment response	9
Ethnicity‐based differences in the incident risk of allergic diseases and autoimmune disorders: A UK‐based retrospective cohort study of 4.4 million participants	9
Clonal mast cell disorders and hereditary α‐tryptasemia as risk factors for anaphylaxis	9
Intradermal Phleum pratense allergoid immunotherapy. Double‐blind, randomized, placebo‐controlled trial	9
Targeting the interleukin‐7 receptor alpha by an anti‐CD127 monoclonal antibody improves allergic airway inflammation in mice	9
Diagnostic performance of serial serum total tryptase measurement to differentiate positive from negative allergy testing among patients with suspected perioperative hypersensitivity	9
Type 2 immunity‐driven diseases: Towards a multidisciplinary approach	9
Heterogeneity of the pharmacologic treatment of allergic rhinitis in Europe based on MIDAS and OTCims platforms	8
Nasal administration of a probiotic assemblage in allergic rhinitis: A randomised placebo‐controlled crossover trial	8
Automatic market research of mobile health apps for the self‐management of allergic rhinitis	8
RAPP‐children: A new tool for assessing quality of life in patients with asthma and rhinitis	8
Microbiome and mycobiome interaction in house dust mites and impact on airway cells	8
A cost‐analysis of outpatient paediatric penicillin allergy de‐labelling using telemedicine	8
Airway Elastin is increased in severe asthma and relates to proximal wall area: histological and computed tomography findings from the U‐BIOPRED severe asthma study	8
Measurement of German cockroach allergens and their isoforms in allergen extracts with mass spectrometry	8
Childhood asthma: Novel endotyping by cytokines, validated through sensitization profiles and clinical characteristics	8
Suitability of low‐dose, open food challenge data to supplement double‐blind, placebo‐controlled data in generation of food allergen threshold dose distributions	8
Involvement of the epidermal growth factor receptor in IL‐13–mediated corticosteroid‐resistant airway inflammation	8
Krebs von den Lungen‐6 (KL‐6) is a pathophysiological biomarker of early‐stage acute hypersensitivity pneumonitis among pigeon fanciers	8
Sex‐specific developmental trajectories of eczema from infancy to age 26 years: A birth cohort study	8
Biomarkers for predicting response to aspirin therapy in aspirin‐exacerbated respiratory disease	8
Impact of COVID‐19 pandemic on quality of life for children and adolescents with food allergy	8
Occupational respiratory allergy to lettuce in lettuce farmers	8
Randomized controlled pilot trial with ion‐exchange water softeners to prevent eczema (SOFTER trial)	8
Hypersensitivity may be involved in severe COVID‐19	8
Protective role of Galectin‐7 for skin barrier impairment in atopic dermatitis	8
Allergenic characterization of Bomb m 4, a 30‐kDa Bombyx mori lipoprotein 6 from silkworm pupa	8
House dust endotoxin, asthma and allergic sensitization through childhood into adolescence	8
Effects of dupilumab treatment on patch test reactions: A retrospective evaluation	8
Vesp v 5 and glycosylated Vesp v 1 are relevant allergens in Vespa velutina nigrithorax anaphylaxis	8
The impact of prenatal dog keeping on infant gut microbiota development	8
Management of IgE‐mediated food allergy in the 21st century	8
Fish collagen as a potential indicator of severe allergic reactions among patients with fish allergies	7
Allergy societies and the formula industry	7
Reliability of the breathing pattern assessment tool for in‐person or remote assessment in people with asthma	7
Allergic bronchopulmonary aspergillosis in India	7
Delayed symptoms and orthostatic intolerance following peanut challenge	7
Airway autoimmunity, asthma exacerbations, and response to biologics	7
Milk allergy guidelines for infants in England promote over‐diagnosis: A cross‐sectional survey	7
Trajectories of early‐onset rhinitis in the Singapore GUSTO mother‐offspring cohort	7
Non–heat inactivated autologous serum increases accuracy of in vitro CFSE lymphocyte proliferation test (LPT) for nickel	7
Protein and carbohydrate content of infant formula purchased in the United States	7
Asia Pacific perspectives on the second year of the COVID‐19 pandemic: A follow‐up survey	7
Airway hyperresponsiveness, remodeling and inflammation in infants with wheeze	7
Pharmacological suppression of the kallikrein kinin system with KVD900: An orally available plasma kallikrein inhibitor for the on‐demand treatment of hereditary angioedema	7
Effect of monoclonal antibody drug therapy on mucosal biomarkers in airway disease: A systematic review	7
Parent‐specific effects on risk of developing allergic sensitization and asthma in childhood	7
Achieving equitable management of allergic disorders and primary immunodeficiency in a Black, Asian and Minority Ethnic population	7
Hexamerin‐like protein 2, a cricket allergen involved in occupational and food allergy	7
Validation study of a new chemiluminescent singleplex IgE assay in a set of Italian allergic rhinitis patients	7
Increased epithelial galectin‐13 expression associates with eosinophilic airway inflammation in asthma	7
Bacterial lysate add‐on therapy to reduce exacerbations in severe asthma: A double‐blind placebo‐controlled trial	7
Basophil activation test for Staphylococcus aureus enterotoxins in severe asthmatic patients	6
Test‐guided dietary management of eczema in children: A randomized controlled feasibility trial (TEST)	6
Efficacy of tezepelumab in patients with evidence of severe allergic asthma: Results from the phase 3 NAVIGATOR study	6
Parental socioeconomic status and asthma in children: Using a population‐based cohort and family design	6
Rectal bleeding and cow’s milk protein‐induced allergic proctocolitis: A prospective study	6
Risk factors associated with rhinitis, allergic conjunctivitis and eczema among schoolchildren in Uganda	6
Elicitors and phenotypes of adult patients with proven IgE‐mediated food allergy and non‐immune‐mediated food hypersensitivity to food additives	6
Limosilactobacillus reuteri DSM‐17938 for preventing cough in adults with mild allergic asthma: A double‐blind randomized placebo‐controlled cross‐over study	6
Inhalation challenge test using pigeon eggs for chronic hypersensitivity pneumonitis	6
Smoking and snuff use in pregnancy and the risk of asthma and wheeze in pre–schoolchildren—A population‐based register study	6
Environmental exposure of Der p 23 in household dust samples	6
GRAded oral challenge for Drug allergy Evaluation—Delabelling described through families' voices	6
Bet v 1 triggers antiviral‐type immune signalling in birch‐pollen‐allergic individuals	6
Paediatric asthma and non‐allergic comorbidities: A review of current risk and proposed mechanisms	6
Clinical and immunological evaluation of cat‐allergic asthmatics living with or without a cat	6
Oscillometry bronchodilator response in adult moderate to severe eosinophilic asthma patients: A prospective cohort study	6
ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta‐analysis	6
A new house dust mite–driven and mast cell–activated model of asthma in the guinea pig	6
Individuals with IgE antibodies to α‐Gal and CCD show specific IgG subclass responses different from subjects non‐sensitized to oligosaccharides	6
Feasibility of an online CBT group intervention for parents of children with food allergy	6
COVID‐19 vaccines and anaphylaxis—evaluation with skin prick testing, basophil activation test and Immunoglobulin E	6
From trained immunity in allergy to trained immunity‐based allergen vaccines	6
Selective inhibition of prostaglandin D2 biosynthesis in human mast cells to overcome need for multiple receptor antagonists: Biochemical consequences	6
DNA methylation down‐regulates integrin β4 expression in asthmatic airway epithelial cells	6
As‐needed anti‐inflammatory reliever therapy for asthma management: evidence and practical considerations	6
Microbiota associations with inflammatory pathways in asthma	6
Allergen extract‐ and component‐based diagnostics in children of the ALLIANCE asthma cohort	6
CD154 (CD40L): A novel aid to document nonimmediate hypersensitivity to amoxicillin or amoxicillin clavulanic acid	6
A novel gain‐of‐function mutation in STAT5B is associated with treatment‐resistant severe atopic dermatitis	6
Delayed reaction in alpha‐gal allergy is reflected in serum levels after ingestion of pork kidney, and absorption is dependent on food processing	6
Diagnostic accuracy of Ara h 2 for detecting peanut allergy in children	6
Loss of smell in patients with aspirin‐exacerbated respiratory disease impacts mental health and quality of life	6