Journal of Internal Medicine

Article	Citations
The Mediterranean diet and health: a comprehensive overview	321
Ambient air pollution and cardiovascular diseases: An umbrella review of systematic reviews and meta‐analyses	216
Prevalence and 6‐month recovery of olfactory dysfunction: a multicentre study of 1363 COVID‐19 patients	167
Short‐term neuropsychiatric outcomes and quality of life in COVID‐19 survivors	149
Homocysteine – from disease biomarker to disease prevention	127
Immunity to SARS‐CoV‐2 induced by infection or vaccination	105
Breathing, speaking, coughing or sneezing: What drives transmission of SARS‐CoV‐2?	105
Nanotechnology for modern medicine: next step towards clinical translation	102
Advances in the Omicron variant development	101
Current treatment of non‐alcoholic fatty liver disease	99
Practical recommendations for timely, accurate diagnosis of symptomatic Alzheimer’s disease (MCI and dementia) in primary care: a review and synthesis	99
Insights into disparities observed with COVID‐19	97
How can dementia and disability be prevented in older adults: where are we today and where are we going?	87
Direct oral anticoagulant use and risk of severe COVID‐19	76
Lessons from 20 years with COX‐2 inhibitors: Importance of dose–response considerations and fair play in comparative trials	69
Association of mitochondrial DNA copy number with metabolic syndrome and type 2 diabetes in 14 176 individuals	68
Pediatric obesity—Long‐term consequences and effect of weight loss	67
Arterial stiffness in acute COVID‐19 and potential associations with clinical outcome	63
Current concepts regarding Graves’ orbitopathy	59
Deep brain stimulation for Parkinson's disease	59
Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer's disease	59
Current and emerging disease‐modulatory therapies and treatment targets for multiple sclerosis	57
Genetics of coronary artery disease in the post‐GWAS era	57
Diagnosis and management of diabetes insipidus for the internist: an update	56
Adherence to a healthy sleep pattern is associated with lower risks of all‐cause, cardiovascular and cancer‐specific mortality	56

Hypocretins (orexins): The ultimate translational neuropeptides	55
Alveolar progenitor cells and the origin of lung cancer	53
Inflammatory and fibrotic mechanisms in NAFLD—Implications for new treatment strategies	53
The role of environmental exposures and gene–environment interactions in the etiology of systemic lupus erythematous	52
Type 2 diabetes and remission: practical management guided by pathophysiology	50
Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID‐19	48
Long‐term neuropsychiatric outcomes in COVID‐19 survivors: A 1‐year longitudinal study	47
Assessment of thirty‐day readmission rate, timing, causes and predictors after hospitalization with COVID‐19	45
Hypoalbuminemia in COVID‐19: assessing the hypothesis for underlying pulmonary capillary leakage	44
Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging	44
Acute odynophagia: A new symptom of COVID‐19 during the SARS‐CoV‐2 Omicron variant wave in Sweden	44
Respiratory dysfunction three months after severe COVID‐19 is associated with gut microbiota alterations	44
The Stockholm CREAtinine Measurements (SCREAM) project: Fostering improvements in chronic kidney disease care	43
Gender‐affirming hormone therapy: An updated literature review with an eye on the future	43
Food allergy and hypersensitivity reactions in children and adults—A review	42
Review of cadmium exposure and smoking‐independent effects on atherosclerotic cardiovascular disease in the general population	42
Gastrointestinal bleeding in hospitalized COVID‐19 patients: a propensity score matched cohort study	41
Half‐year follow‐up of patients recovering from severe COVID‐19: Analysis of symptoms and their risk factors	41
Increased vulnerability to COVID‐19 in chronic kidney disease	41
Sarcoidosis: Epidemiology and clinical insights	39
Outcomes of COVID‐19‐positive acute coronary syndrome patients: A multisource electronic healthcare records study from England	39
Is obesity a manifestation of systemic racism? A ten‐point strategy for study and intervention	39
Low‐dose computed tomography lung cancer screening: Clinical evidence and implementation research	39
Remnant cholesterol predicts progression of diabetic nephropathy and retinopathy in type 1 diabetes	38
Association of the metabolic syndrome with mortality and major adverse cardiac events: A large chronic kidney disease cohort	38
Transthyretin amyloid deposits in lumbar spinal stenosis and assessment of signs of systemic amyloidosis	37
The circadian syndrome predicts cardiovascular disease better than metabolic syndrome in Chinese adults	37
An update on polymyalgia rheumatica	36
Cardiovascular risk factors and lifestyle behaviours in relation to longevity: a Mendelian randomization study	36
Inflammatory bowel disease and psoriasis: modernizing the multidisciplinary approach	36
Cyclosporine A plus low‐dose steroid treatment in COVID‐19 improves clinical outcomes in patients with moderate to severe disease: A pilot study	35
Risk of primary liver cancer in acute hepatic porphyria patients: A matched cohort study of 1244 individuals	35
Induction of specific brain oscillations may restore neural circuits and be used for the treatment of Alzheimer's disease	35
Dilated cardiomyopathy and chronic cardiac inflammation: Pathogenesis, diagnosis and therapy	35
COVID‐19 in Latin America and the Caribbean: Two years of the pandemic	35
Abnormal thyroid function is common in takotsubo syndrome and depends on two distinct mechanisms: results of a multicentre observational study	35
The complexity of kidney disease and diagnosing it – cystatin C, selective glomerular hypofiltration syndromes and proteome regulation	34
Associations between nutritional frailty and 8‐year all‐cause mortality in older adults: The Salus in Apulia Study	34
The influence of the blood–brain barrier in the treatment of brain tumours	33
Seropositivity in blood donors and pregnant women during the first year of SARS‐CoV‐2 transmission in Stockholm, Sweden	33
Prevalence and 24‐month recovery of olfactory dysfunction in COVID‐19 patients: A multicentre prospective study	33
Systemic lupus erythematosus and cardiovascular disease	32
Humoral response to two doses of BNT162b2 vaccination in people with HIV	32
New tuberculosis vaccines: advances in clinical development and modelling	32
Antibiotics and mental health: The good, the bad and the ugly	32
Genetic and molecular architecture of familial hypercholesterolemia	32
Gene therapy for ischaemic heart disease and heart failure	32
Developmental regulation of barrier‐ and non‐barrier blood vessels in the CNS	31
Post COVID‐19 condition diagnosis: A population‐based cohort study of occurrence, associated factors, and healthcare use by severity of acute infection	31
Global guidance for the recognition, diagnosis, and management of tumor‐induced osteomalacia	31

Is systemic inflammation a missing link between periodontitis and hypertension? Results from two large population‐based surveys	30
Muscle‐strengthening activities and risk of cardiovascular disease, type 2 diabetes, cancer and mortality: A review of prospective cohort studies	30
So close, and yet so far away: The dichotomy of the specific immune response and inflammation in psoriasis and atopic dermatitis	30
Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis	29
Micronutrient deficiencies in heart failure: Mitochondrial dysfunction as a common pathophysiological mechanism?	29
Human white adipose tissue: A highly dynamic metabolic organ	29
Vitamin D, respiratory infections, and chronic disease: Review of meta‐analyses and randomized clinical trials	28
Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID‐19 convalescent plasma clinical trial	28
Hypertension genetics past, present and future applications	28
Cause of death based on systematic post‐mortem studies in patients with positive SARS‐CoV‐2 tissue PCR during the COVID‐19 pandemic	28
One‐year persistent symptoms and functional impairment in SARS‐CoV‐2 positive and negative individuals	27
Endovascular thrombectomy for acute ischemic stroke	27
The roles of free iron, heme, haemoglobin, and the scavenger proteins haemopexin and alpha‐1‐microglobulin in preeclampsia and fetal growth restriction	27
Immunogenicity of SARS‐CoV‐2 mRNA vaccine in solid organ transplant recipients	27
Ursodeoxycholic acid is associated with a reduction in SARS‐CoV‐2 infection and reduced severity of COVID‐19 in patients with cirrhosis	27
PCSK9 inhibitors for COVID‐19: an opportunity to enhance the antiviral action of interferon in patients with hypercholesterolaemia	27
Postural orthostatic tachycardia syndrome is associated with significant employment and economic loss	26
The potential of DNA methylation as a biomarker for obesity and smoking	26
Genetic characteristics predict response to venetoclax plus hypomethylating agents in relapsed or refractory acute myeloid leukemia	25
Prevalence and severity of coronary artery disease linked to prognosis in psoriasis and psoriatic arthritis patients: a multi‐centre cohort study	25
Changes in eicosapentaenoic acid and docosahexaenoic acid and risk of cardiovascular events and atrial fibrillation: A secondary analysis of the OMEMI trial	25
The endocannabinoid system – current implications for drug development	24
BMI is positively associated with accelerated epigenetic aging in twin pairs discordant for body mass index	24
Central nervous system zoning: How brain barriers establish subdivisions for CNS immune privilege and immune surveillance	24
Shared decision‐making interventions: An overview and a meta‐analysis of their impact on vaccine uptake	24
Can we cure diabetic kidney disease? Present and future perspectives from a nephrologist's point of view	23
Aerobic exercise training and neurocognitive function in cognitively normal older adults: A one‐year randomized controlled trial	23
Promotion of vascular integrity in sepsis through modulation of bioactive adrenomedullin and dipeptidyl peptidase 3	22
Reported muscle symptoms during statin treatment amongst Italian dyslipidaemic patients in the real‐life setting: the PROSISA Study	22
Does exercise prevent major non‐communicable diseases and premature mortality? A critical review based on results from randomized controlled trials	22
Gut microbiome and amyotrophic lateral sclerosis: A systematic review of current evidence	22
Osteoarthritis, part of life or a curable disease? A bird's‐eye view	22
Predictive models for clinical decision making: Deep dives in practical machine learning	21
Post‐Covid‐19‐vaccination adverse events and healthcare utilization among individuals with or without previous SARS‐CoV‐2 infection	21
Long‐term corticosteroid use, adrenal insufficiency and the need for steroid‐sparing treatment in adult severe asthma	21
Lipoprotein(a) and SARS‐CoV‐2 infections: Susceptibility to infections, ischemic heart disease and thromboembolic events	21
Increased fracture risk after discontinuation of anti‐osteoporosis medications among hip fracture patients: A population‐based cohort study	21
Incidence and survival of haemophagocytic lymphohistiocytosis: A population‐based cohort study from England	21
Iron deficiency screening is a key issue in chronic inflammatory diseases: A call to action	21
Critical COVID‐19 is associated with distinct leukocyte phenotypes and transcriptome patterns	21
ACE inhibitors, angiotensin receptor blockers and endothelial injury in COVID‐19	21
Cognitive dysfunction in post‐COVID‐19 condition: Mechanisms, management, and rehabilitation	20
Malmö POTS symptom score: Assessing symptom burden in postural orthostatic tachycardia syndrome	20
Implementation of precision medicine in healthcare—A European perspective	20
Cannabidiol‐associated hepatotoxicity: A systematic review and meta‐analysis	19
Telehealth mitigates COPD disease progression compared to standard of care: a randomized controlled crossover trial	19
Discrepancies between actual weight, weight perception and weight loss intention amongst persons with NAFLD	19
Impact of the post‐COVID‐19 condition on health care after the first disease wave in Lombardy	19
Peripheral lymphocyte count defines the clinical phenotypes and prognosis in patients with anti‐MDA5‐positive dermatomyositis	19
Twenty‐five years of biologicals in IBD: What´s all the hype about?	19
Low anti‐SARS‐CoV‐2 S antibody levels predict increased mortality and dissemination of viral components in the blood of critical COVID‐19 patients	18
The impact of a tailored mindfulness‐based program for resident physicians on distress and the quality of care: A randomised controlled trial	18
Evaluation of SARS‐CoV‐2 antibody levels on hospital admission as a correlate of protection against mortality	18
Technological readiness and implementation of genomic‐driven precision medicine for complex diseases	18
Treating hypothyroidism is not always easy: When to treat subclinical hypothyroidism, TSH goals in the elderly, and alternatives to levothyroxine monotherapy	17
Genome‐wide search for genes affecting the age at diagnosis of type 1 diabetes	17
Clinical features of patients who had two COVID‐19 episodes: a European multicentre case series	17
The role of extracellular histones in COVID‐19	17
RNAi therapy with givosiran significantly reduces attack rates in acute intermittent porphyria	17
Calcitonin gene‐related peptide (CGRP) is a key molecule released in acute migraine attacks—Successful translation of basic science to clinical practice	17
Antibody‐dependent neutralizing capacity of the SARS‐CoV‐2 vaccine BNT162b2 with and without previous COVID‐19 priming	17
Vitamin D and COVID‐19—Revisited	17
Hospital at home for acute medical illness: The 21st century acute medical unit for a changing population	16
Cerebrotendinous xanthomatosis without neurological involvement	16
Neuroimaging phenotypes of CSF1R‐related leukoencephalopathy: Systematic review, meta‐analysis, and imaging recommendations	16
4D flow MRI hemodynamic biomarkers for cerebrovascular diseases	16
Lung perfusion disturbances in nonhospitalized post‐COVID with dyspnea—A magnetic resonance imaging feasibility study	16
Blood metabolite profiles linking dietary patterns with health—Toward precision nutrition	16
The pathogenesis of microthrombi in COVID‐19 cannot be controlled by DOAC: NETosis should be the target	16
Homocysteine elevation in givosiran treatment: Suggested ALAS1 siRNA effect on cystathionine beta‐synthase	16
Growth hormone deficiency in adults with hypopituitarism—What are the risks and can they be eliminated by therapy?	16
Low antispike antibody levels correlate with poor outcomes in COVID‐19 breakthrough hospitalizations	16
A follow‐up survey of patients with acquired angioedema due to C1‐inhibitor deficiency	16
Real‐world evidence for the effectiveness of vitamin D supplementation in reduction of total and cause‐specific mortality	16
Reduction of protein‐bound uraemic toxins in plasma of chronic renal failure patients: A systematic review	16
Primary Sjögren's syndrome: Longitudinal real‐world, observational data on health‐related quality of life	16
Precision medicine in complex diseases—Molecular subgrouping for improved prediction and treatment stratification	16
Acrodermatitis chronica atrophicans: clinical and microbiological characteristics of a cohort of 693 Slovenian patients	15
Respiratory and systemic monocytes, dendritic cells, and myeloid‐derived suppressor cells in COVID‐19: Implications for disease severity	15
Tenosynovial complications identify TTR cardiac amyloidosis among patients with hypertrophic cardiomyopathy phenotype	15

Estimated salt intake and risk of atrial fibrillation in a prospective community‐based cohort	15
Classic heat stroke in a desert climate: A systematic review of 2632 cases	15
Microbiological etiology in prosthetic valve endocarditis: A nationwide registry study	15
Risk factors for anti‐drug antibody formation to infliximab: Secondary analyses of a randomised controlled trial	15
The novel collagen matrikine, endotrophin, is associated with mortality and cardiovascular events in patients with atherosclerosis	14
Application of precision medicine in clinical routine in haematology—Challenges and opportunities	14
Antimicrobial therapy during cancer treatment: Beyond antibacterial effects	14
Does diet influence aging? Evidence from animal studies	14
The clinical and molecular cardiometabolic fingerprint of an exploratory psoriatic arthritis cohort is associated with the disease activity and differentially modulated by methotrexate and apremilast	14
Associations of plasma TMAO and its precursors with stroke risk in the general population: A nested case‐control study	14
Tobacco smoking confers risk for severe COVID‐19 unexplainable by pulmonary imaging	14
Effectiveness of REGEN‐COV antibody cocktail against the B.1.617.2 (delta) variant of SARS‐CoV‐2: A cohort study	14
Fasting intervention and its clinical effects on the human host and microbiome	14
Aging biomarkers: Potential mediators of association between long‐term ozone exposure and risk of atherosclerosis	14
Network meta‐analysis of medical therapy efficacy in more than 90,000 patients with heart failure and reduced ejection fraction	14
Tuberculosis in patients with systemic lupus erythematosus–a 37‐year longitudinal survey‐based study	14
Diagnostic performance of 18F‐FDG‐PET/CT in inflammation of unknown origin: A clinical series of 317 patients	13
Is mapping the BCG vaccine‐induced immune responses the key to improving the efficacy against tuberculosis?	13
Mechanistic insights into the primary and secondary alterations of renal ion and water transport in the distal nephron	13
Chronic rhinosinusitis is associated with prolonged SARS‐CoV‐2 RNA shedding in upper respiratory tract samples: A case‐control study	13
Randomized clinical trial of BCG vaccine in patients with convalescent COVID‐19: Clinical evolution, adverse events, and humoral immune response	13
Complications following novel therapies for non‐small cell lung cancer	13
Renal function in patients with significant tricuspid regurgitation: pathophysiological mechanisms and prognostic implications	12
Precision cancer medicine: Concepts, current practice, and future developments	12
Bacterial meningitis: Aetiology, risk factors, disease trends and severe sequelae during 50 years in Sweden	12
Liver damage promotes pro‐inflammatory T‐cell responses against apolipoprotein B‐100	12
Appropriate care for the elderly in the ICU	12
Hyperglycaemia‐associated Caspase‐3 predicts diabetes and coronary artery disease events	12
Glucagon‐like peptide‐1: Are its roles as endogenous hormone and therapeutic wizard congruent?	12
Microbiota restoration for recurrent Clostridioides difficile: Getting one step closer every day!	12
Risk of fractures and postfracture mortality in 3980 people with primary biliary cholangitis: A population‐based cohort study	12
The development of preprints during the COVID‐19 pandemic	12
Perspectives on improving blood pressure control to reduce the clinical and economic burden of hypertension	12
Risk for hepatic and extra‐hepatic outcomes in nonalcoholic fatty liver disease	12
Patterns of repeated diagnostic testing for COVID‐19 in relation to patient characteristics and outcomes	12
Tocilizumab in COVID‐19 interstitial pneumonia	11
Diabetic diarrhoea: A study on gastrointestinal motility, pH levels and autonomic function	11
Factors influencing the immune response over 15 months after SARS‐CoV‐2 infection: A longitudinal population‐wide study in the Faroe Islands	11
Diverging trends for onset of acute myocardial infarction, heart failure, stroke and mortality in young males: role of changes in obesity and fitness	11
Myocardial infarction in diffuse large B‐cell lymphoma patients – a population‐based matched cohort study	11
Preconception origins of asthma, allergies and lung function: The influence of previous generations on the respiratory health of our children	11
Soat2 ties cholesterol metabolism to β‐oxidation and glucose tolerance in male mice	11
Towards precision medicine in lymphoid malignancies	11
Neutrophil count predicts clinical outcome in hospitalized COVID‐19 patients: Results from the NOR‐Solidarity trial	11
Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases	11
Inflammatory bowel disease in Hermansky–Pudlak syndrome: a retrospective single‐centre cohort study	10
Increased circulating phenylacetylglutamine concentration elevates the predictive value of cardiovascular event risk in heart failure patients	10
Broadening risk factor or disease definition as a driver for overdiagnosis: A narrative review	10
Acute hepatic porphyria and maternal health: Clinical and biochemical follow‐up of 44 pregnancies	10
The HDL mimetic CER‐001 remodels plasma lipoproteins and reduces kidney lipid deposits in inherited lecithin:cholesterol acyltransferase deficiency	10
Targeting the FGF19–FGFR4 pathway for cholestatic, metabolic, and cancerous diseases	10
Good old BCG – what a century‐old vaccine can contribute to modern medicine	10
Effects of PNPLA3 I148M on hepatic lipid and very‐low‐density lipoprotein metabolism in humans	10
Connecting the epigenome, metabolome and proteome for a deeper understanding of disease	10
Apolipoprotein C‐III predicts cardiovascular events and mortality in individuals with type 1 diabetes and albuminuria	10
On the relationship between BCG coverage and national COVID‐19 outcome: could ‘heterologous’ herd immunity explain why some countries are better off?	10
Neurobiology of eating behavior, nutrition, and health	10
MAFLD definition underestimates the risk to develop HCC in genetically predisposed patients	10
How many steps a day to reduce the risk of all‐cause mortality? A dose–response meta‐analysis	10
Diet strategies for promoting healthy aging and longevity: An epidemiological perspective	10
Small fiber neuropathy in hypermobile Ehlers Danlos syndrome/hypermobility spectrum disorder	10
Excessive daytime sleepiness, morning tiredness and major adverse cardiovascular events in patients with chronic coronary syndrome	10
Time‐dependent lipid profile inversely associates with mortality in hemodialysis patients – independent of inflammation/malnutrition	10
Post‐acute cognitive and mental health outcomes amongst COVID‐19 survivors: early findings and a call for further investigation	10
Pseudoxanthoma elasticum overlaps hereditary spastic paraplegia type 56	10
Increased mortality of patients with alcohol‐related liver diseases during the COVID‐19 pandemic in the United States	9
Risk factors for impaired respiratory function post COVID‐19: A prospective cohort study of nonhospitalized and hospitalized patients	9
Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2‐cohort study	9
Effective prognostic and clinical risk stratification in COVID‐19 using multimodality biomarkers	9
Cardiorespiratory dysautonomia in post‐COVID‐19 condition: Manifestations, mechanisms and management	9
Vitamin D–binding protein, total, “nonbioavailable,” bioavailable, and free 25‐hydroxyvitamin D, and mortality in a large population‐based cohort of older adults	9
The association between plasma metabolites and future risk of all‐cause mortality	9
Pancreatic incidentalomas: Investigation and management	9
Efficacy and safety of thrombolytic therapy for portal venous system thrombosis: A systematic review and meta‐analysis	9
PCSK9 inhibition with alirocumab decreases plasma lipoprotein(a) concentration by a dual mechanism of action in statin‐treated patients with very high apolipoprotein(a) concentration	9
Risk of venous and arterial thromboembolism in patients with giant cell arteritis and/or polymyalgia rheumatica: A Veterans Health Administration population‐based study in the United States	9
Targeting stem cells in myelodysplastic syndromes and acute myeloid leukemia	9
Ultradian hydrocortisone replacement alters neuronal processing, emotional ambiguity, affect and fatigue in adrenal insufficiency: The PULSES trial	9
Adherence to a Mediterranean lifestyle improves metabolic status in coronary heart disease patients: A prospective analysis from the CORDIOPREV study	9
Working in value‐discrepant environments inhibits clinicians’ ability to provide compassion and reduces well‐being: A cross‐sectional study	9
Scoring of medial arterial calcification predicts cardiovascular events and mortality after kidney transplantation	9
Angiopoietin‐2 and angiopoietin‐like 4 protein provide prognostic information in patients with suspected acute coronary syndrome	9
Cholestatic liver injury in COVID‐19 is a rare and distinct entity and is associated with increased mortality	9
Blood group A epitopes do not facilitate entry of SARS‐CoV‐2	9
Risk of fractures and subsequent mortality in non‐alcoholic fatty liver disease: A nationwide population‐based cohort study	9
Efficacy and safety of intravenous bevacizumab on severe bleeding associated with hemorrhagic hereditary telangiectasia: A national, randomized multicenter trial	9
Acute myeloid leukaemia in patients we judge as being older and/or unfit	9
LDL cholesterol level as a risk factor for retinopathy and nephropathy in children and adults with type 1 diabetes mellitus: A nationwide cohort study	9
Large‐scale screening studies for atrial fibrillation – is it worth the effort?	9
Dual versus single long‐acting bronchodilator use could raise acute coronary syndrome risk by over 50%: A population‐based nested case–control study	8
Bowel ischemia as onset of COVID‐19 in otherwise asymptomatic patients with persistently negative swab	8
The risk of renal comorbidities in celiac disease patients depends on the phenotype of celiac disease	8
Novel precision medicine approaches and treatment strategies in hematological malignancies	8
Clinical use of lefamulin: A first‐in‐class semisynthetic pleuromutilin antibiotic	8
The red blood cell as a mediator of endothelial dysfunction in patients with familial hypercholesterolemia and dyslipidemia	8