OOIR: Observatory of International Research

Papers

(The TQCC of Platelets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)

Article	Citations
Immunothrombosis and thromboinflammation in host defense and disease	93
A proof of evidence supporting abnormal immunothrombosis in severe COVID-19: naked megakaryocyte nuclei increase in the bone marrow and lungs of critically ill patients	52
Platelet Rich Plasma in Orthopedic Surgical Medicine.	50
PRP in wound healing applications	40
Technical and biological review of authorized medical devices for platelets-rich plasma preparation in the field of regenerative medicine	40
Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity	38
Platelet rich plasma in oral and maxillofacial surgery from the perspective of composition	34
The thrombopoietin receptor: revisiting the master regulator of platelet production	32
Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases	32
Cerebral venous sinus thrombosis associated with spontaneous heparin-induced thrombocytopenia syndrome after total knee arthroplasty	30
Search for SARS-CoV-2 RNA in platelets from COVID-19 patients	30
Over time relationship between platelet reactivity, myocardial injury and mortality in patients with SARS-CoV-2-associated respiratory failure	28
Rotational thromboelastometry (ROTEM) profiling of COVID–19 patients	25
Neonatal platelet physiology and implications for transfusion	25
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	25
Platelet-rich plasma promotes bone formation, restrains adipogenesis and accelerates vascularization to relieve steroids-induced osteonecrosis of the femoral head	24
Efficacy and safety evaluation of avatrombopag in immune thrombocytopenia: analyses of a phase III study and long-term extension	24
Isolation of murine bone marrow by centrifugation or flushing for the analysis of hematopoietic cells – a comparative study	23
Risk of major adverse cardiovascular events of CYP2C19 loss-of-function genotype guided prasugrel/ticagrelor vs clopidogrel therapy for acute coronary syndrome patients undergoing percutaneous	22
Application of Platelet Rich Fibrin in Tissue Engineering: Focus on Bone Regeneration	21
Platelets and viruses	21
The structure of CLEC-2: mechanisms of dimerization and higher-order clustering	20
Extensive characterization of the composition and functional activities of five preparations of human platelet lysates for dedicated clinical uses	18
Human platelet lysates for human cell propagation	18
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	18

Platelet–leukocyte interactions in the pathogenesis of viral infections	17
Bioinspired artificial platelets: past, present and future	17
Platelets and renal failure in the SARS-CoV-2 syndrome	17
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	16
Immobilized collagen prevents shedding and induces sustained GPVI clustering and signaling in platelets	16
Platelets in dengue infection: more than a numbers game	15
Structure-function relationship of the platelet glycoprotein VI (GPVI) receptor: does it matter if it is a dimer or monomer?	15
The efficacy and safety of thrombopoietin receptor agonists in patients with chronic liver disease undergoing elective procedures: a systematic review and meta-analysis	14
Alterations in platelets during SARS-CoV-2 infection	14
Cytosolic and mitochondrial Ca²⁺ signaling in procoagulant platelets	14
EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling	14
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function	13
Zinc: an endogenous and exogenous regulator of platelet function during hemostasis and thrombosis	13
Release of α-granule contents during platelet activation	13
Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B	13
Frozen and cold-stored platelets: reconsidered platelet products	13
Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets	13
Prevalence and natural history of variants in the ANKRD26 gene: a short review and update of reported cases	13
Platelet reticulated forms, size indexes and functional activity. Interactions in healthy volunteers.	13
Diagnostic and prognostic role of platelets in patients with sepsis and septic shock	12
Left ventricular assist device implantation causes platelet dysfunction and proinflammatory platelet-neutrophil interaction	12
Efficacy and safety of eltrombopag in Chinese patients with chronic immune thrombocytopenia: stage 2 results from a multicenter phase III study	12
Platelet count and function in umbilical cord blood versus peripheral blood in term neonates	12
Platelet Function Assays for the Diagnosis of Aspirin Resistance	12
Severe thrombocytopenia in adults undergoing extracorporeal membrane oxygenation is predictive of thrombosis	12
Antiplatelet drugs and liver fibrosis	11
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	11
Overcoming challenges in developing small molecule inhibitors for GPVI and CLEC-2	11
Platelet-derived microparticles stimulated by anti-β ₂ GPI/β ₂ GPI complexes induce pyroptosis of endothelial cells in antiphospho	11
Platelet activation by charged ligands and nanoparticles: platelet glycoprotein receptors as pattern recognition receptors	11
GPIb-IX-V and platelet clearance	10
Injectable platelet-rich fibrin positively regulates osteogenic differentiation of stem cells from implant hole via the ERK1/2 pathway	10
Differential effect of clopidogrel and ticagrelor on leukocyte count in relation to patient characteristics, biomarkers and genotype: a PLATO substudy	10
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans	10
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	10
Sex differences in antiplatelet therapy: state-of-the art	10
P2X1: a unique platelet receptor with a key role in thromboinflammation	10
Thrombocytopenia and platelet count recovery in patients with sepsis-3: a retrospective observational study	10
High-efficiency unassisted transfection of platelets with naked double-stranded miRNAs modulates signal-activated translation and platelet function	9
Investigation of fibrinogen in early bleeding of patients with newly diagnosed acute promyelocytic leukemia	9
The enigmatic nature of the triggering receptor expressed in myeloid cells -1 (TLT- 1)	9
Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation	9
Higher body mass index raises immature platelet count: potential contribution to obesity-related thrombosis	9
Distribution and quantification of activated platelets in platelet-rich fibrin matrices	9
Immature platelet indices alongside procalcitonin for sensitive and specific identification of bacteremia in the intensive care unit	9
Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and convalescent phase of COVID-19	9
Signaling mechanisms of the platelet glycoprotein Ib-IX complex	9
A proprietary GMP human platelet lysate for the expansion of dermal fibroblasts for clinical applications	9
Selective inhibition of thromboinflammation in COVID-19 by Btk inhibitors	9
High extracellular phosphate increases platelet polyphosphate content	9

Effect of differently coated silver nanoparticles on hemostasis	9
Whole blood flow cytometry protocol for the assessment of platelet phenotype, function, and cellular interactions	8
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	8
Optimized tool for evaluation of platelet function measured by impedance aggregometry	8
Factor Xa and thrombin induce endothelial progenitor cell activation. The effect of direct oral anticoagulants	8
Evolution of platelet activation parameters during septic shock in intensive care unit	8
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	8
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	8
Association of lipoprotein(a) with platelet aggregation and thrombogenicity in patients undergoing percutaneous coronary intervention	8
Management of immune thrombotic thrombocytopenic purpura with caplacizumab: a Canadian, single-centre, real-world experience	8
Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape	8
Whole blood platelet aggregation measurement by Multiplate™: potential diagnostic inaccuracy of correcting the results for the sample platelet count	7
New presentations and exacerbations of immune thrombocytopenia after coronavirus disease 2019 vaccinations: the Taiwan experience	7
Reply to “Peripheral versus central venous blood sampling does not influence the assessment of platelet activation in cirrhosis”	7
Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study	7
Human Platelets and Influenza Virus: Internalization and Platelet Activation	7
Enrichment of plasma in platelets and extracellular vesicles by the counterflow to erythrocyte settling	7
Statins potentiate the antibacterial effect of platelets on Staphylococcus aureus	7
Refractory immune thrombocytopenia successfully treated with bortezomib in a child with 22q11.2 deletion syndrome, complicated by Evans syndrome and hypogammaglobulinemia	7
The potency of selatogrel, a reversible antagonist of the P2Y12 receptor, is affected by calcium concentration	7
Pathogen inactivation of platelets for transfusion	7
Helicobacter pylori protein that binds to and activates platelet specifically reacts with sera of H. pylori-associated chronic immune thrombocytopenia	7
Platelets: bridging thrombosis and inflammation	7
Relationship between Hepatitis B virus infection and platelet production and dysfunction	7
Prognostic significance of thrombocytosis in lung cancer: a systematic review and meta-analysis	7
Association between platelet counts and morbidity and mortality after endovascular repair for type B aortic dissection	7
Recovery of platelet reactivity following cessation of either aspirin or ticagrelor in patients treated with dual antiplatelet therapy following percutaneous coronary intervention: a GLOBAL LEADERS su	7
Why do platelets express K⁺ channels?	7
Platelet activation and aggregation in different centrifugal-flow left ventricular assist devices	7
Novel antiplatelet strategies targeting VWF and GPIb	7