OOIR: Observatory of International Research

Papers

(The TQCC of Platelets is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-12-01 to 2024-12-01.)

Article	Citations
Platelet Rich Plasma in Orthopedic Surgical Medicine.	57
Platelet rich plasma in oral and maxillofacial surgery from the perspective of composition	38
Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity	37
The thrombopoietin receptor: revisiting the master regulator of platelet production	37
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	35
Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases	33
Neonatal platelet physiology and implications for transfusion	30
Search for SARS-CoV-2 RNA in platelets from COVID-19 patients	30
Over time relationship between platelet reactivity, myocardial injury and mortality in patients with SARS-CoV-2-associated respiratory failure	28
Efficacy and safety evaluation of avatrombopag in immune thrombocytopenia: analyses of a phase III study and long-term extension	25
Rotational thromboelastometry (ROTEM) profiling of COVID–19 patients	25
Application of Platelet Rich Fibrin in Tissue Engineering: Focus on Bone Regeneration	22
Release of α-granule contents during platelet activation	22
Platelets and viruses	22
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	20
The structure of CLEC-2: mechanisms of dimerization and higher-order clustering	20
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	18
Platelet–leukocyte interactions in the pathogenesis of viral infections	18
Bioinspired artificial platelets: past, present and future	18
Immobilized collagen prevents shedding and induces sustained GPVI clustering and signaling in platelets	17
Diagnostic and prognostic role of platelets in patients with sepsis and septic shock	17
Platelets in dengue infection: more than a numbers game	16
Structure-function relationship of the platelet glycoprotein VI (GPVI) receptor: does it matter if it is a dimer or monomer?	16
Cytosolic and mitochondrial Ca²⁺ signaling in procoagulant platelets	16
The efficacy and safety of thrombopoietin receptor agonists in patients with chronic liver disease undergoing elective procedures: a systematic review and meta-analysis	15

Alterations in platelets during SARS-CoV-2 infection	15
Platelet Function Assays for the Diagnosis of Aspirin Resistance	14
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	14
Platelet reticulated forms, size indexes and functional activity. Interactions in healthy volunteers.	14
Prevalence and natural history of variants in the ANKRD26 gene: a short review and update of reported cases	14
Severe thrombocytopenia in adults undergoing extracorporeal membrane oxygenation is predictive of thrombosis	14
Frozen and cold-stored platelets: reconsidered platelet products	14
Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B	13
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	13
Sex differences in antiplatelet therapy: state-of-the art	13
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function	13
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	13
Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets	13
Left ventricular assist device implantation causes platelet dysfunction and proinflammatory platelet-neutrophil interaction	13
EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling	13
Differential effect of clopidogrel and ticagrelor on leukocyte count in relation to patient characteristics, biomarkers and genotype: a PLATO substudy	12
Platelet-derived microparticles stimulated by anti-β ₂ GPI/β ₂ GPI complexes induce pyroptosis of endothelial cells in antiphospho	12
Signaling mechanisms of the platelet glycoprotein Ib-IX complex	12
Platelet activation by charged ligands and nanoparticles: platelet glycoprotein receptors as pattern recognition receptors	12
Antiplatelet drugs and liver fibrosis	11
Overcoming challenges in developing small molecule inhibitors for GPVI and CLEC-2	11
GPIb-IX-V and platelet clearance	11
Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and convalescent phase of COVID-19	10
Injectable platelet-rich fibrin positively regulates osteogenic differentiation of stem cells from implant hole via the ERK1/2 pathway	10
Distribution and quantification of activated platelets in platelet-rich fibrin matrices	10
The enigmatic nature of the triggering receptor expressed in myeloid cells -1 (TLT- 1)	10
Thrombocytopenia and platelet count recovery in patients with sepsis-3: a retrospective observational study	10
Higher body mass index raises immature platelet count: potential contribution to obesity-related thrombosis	10
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	10
P2X1: a unique platelet receptor with a key role in thromboinflammation	10
Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation	10
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans	10
A proprietary GMP human platelet lysate for the expansion of dermal fibroblasts for clinical applications	9
Platelet extracellular vesicles are efficient delivery vehicles of doxorubicin, an anti-cancer drug: preparation and in vitro characterization	8
The role of viscoelastic testing in assessing peri-interventional platelet function and coagulation	8
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of BMS-986141, a novel, reversible, small-molecule, PAR4 agonist in non-Japanese and Japanese healthy participants	8
Circulating microRNAs as biomarkers and mediators of platelet activation	8
Why do platelets express K⁺ channels?	8
Ionotropic glutamate receptors in platelets: opposing effects and a unifying hypothesis	8
Evolution of platelet activation parameters during septic shock in intensive care unit	8
Management of immune thrombotic thrombocytopenic purpura with caplacizumab: a Canadian, single-centre, real-world experience	8
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	8
The efficacy of platelet rich plasma on anterior cruciate ligament reconstruction: a systematic review and meta-analysis	7
The potency of selatogrel, a reversible antagonist of the P2Y12 receptor, is affected by calcium concentration	7
Platelet-leukocyte aggregate formation and inflammation in patients with pulmonary arterial hypertension and CTEPH	7
Recovery of platelet reactivity following cessation of either aspirin or ticagrelor in patients treated with dual antiplatelet therapy following percutaneous coronary intervention: a GLOBAL LEADERS su	7
Effect of leukocyte-platelet fibrin-rich wound reconstruction followed by full-thickness skin grafting in the treatment of diabetic foot Wagner grade 4 ulcer gangrene (toe area)	7
Human Platelets and Influenza Virus: Internalization and Platelet Activation	7
Is the endogenous ligand for PEAR1 a proteoglycan: clues from the sea	7
Whole blood platelet aggregation measurement by Multiplate™: potential diagnostic inaccuracy of correcting the results for the sample platelet count	7

Complement activation negatively affects the platelet response to thrombopoietin receptor agonists in patients with immune thrombocytopenia: a prospective cohort study	7
New presentations and exacerbations of immune thrombocytopenia after coronavirus disease 2019 vaccinations: the Taiwan experience	7
Pathogen inactivation of platelets for transfusion	7
Mean platelet volume: a prognostic marker in heart failure with preserved ejection fraction	7
Platelets: bridging thrombosis and inflammation	7
Platelet activation and aggregation in different centrifugal-flow left ventricular assist devices	7
Relationship between Hepatitis B virus infection and platelet production and dysfunction	7
Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes	7
Effect of avatrombopag in the management of severe and refractory chemotherapy-induced thrombocytopenia (CIT) in patients with solid tumors	7
Reply to “Peripheral versus central venous blood sampling does not influence the assessment of platelet activation in cirrhosis”	7
Helicobacter pylori protein that binds to and activates platelet specifically reacts with sera of H. pylori-associated chronic immune thrombocytopenia	7
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy	7
Enrichment of plasma in platelets and extracellular vesicles by the counterflow to erythrocyte settling	7
Refractory immune thrombocytopenia successfully treated with bortezomib in a child with 22q11.2 deletion syndrome, complicated by Evans syndrome and hypogammaglobulinemia	7
“Tailored” antiplatelet bridging therapy with cangrelor: moving toward personalized medicine	6
Eltrombopag modulates the phenotypic evolution and potential immunomodulatory roles of monocytes/macrophages in immune thrombocytopenia	6
Hemostasis-on-a-chip / incorporating the endothelium in microfluidic models of bleeding	6
^{Irradiation of platelets in transfusion medicine: risk and benefit judgments}	6
Intravenous abciximab as a rescue therapy for immediate reocclusion after successful mechanical thrombectomy in acute ischemic stroke patients	6
Platelet glycogenolysis is important for energy production and function	6
Immature platelets in COVID-19	6
Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength	6
Flow cytometry identifies an early stage of platelet apoptosis produced by agonists of the P2X1 and P2X7 receptors	6
Innate immune TLR7 signaling mediates platelet activation and platelet-leukocyte aggregate formation in murine bacterial sepsis	6
Exacerbation of immune thrombocytopenia following initial and booster vaccination with Pfizer-BioNTech COVID-19 vaccine	6
Fatal cerebral hemorrhage in a patient with thrombotic thrombocytopenic purpura with a normal platelet count during treatment with caplacizumab	6
Platelets after burn injury – hemostasis and beyond	6
Comparison of the effects of platelet concentrates produced by high and low-speed centrifugation protocols on the healing of critical-size defects in rat calvaria: a microtomographic and histomorphome	6
Cold stored platelets in the management of bleeding: is it about bioenergetics?	6