OOIR: Observatory of International Research

Papers

(The TQCC of Platelets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Platelet Rich Plasma in Orthopedic Surgical Medicine.	57
Technical and biological review of authorized medical devices for platelets-rich plasma preparation in the field of regenerative medicine	45
PRP in wound healing applications	43
Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity	37
Platelet rich plasma in oral and maxillofacial surgery from the perspective of composition	37
The thrombopoietin receptor: revisiting the master regulator of platelet production	37
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	35
Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases	33
Search for SARS-CoV-2 RNA in platelets from COVID-19 patients	30
Over time relationship between platelet reactivity, myocardial injury and mortality in patients with SARS-CoV-2-associated respiratory failure	28
Neonatal platelet physiology and implications for transfusion	27
Efficacy and safety evaluation of avatrombopag in immune thrombocytopenia: analyses of a phase III study and long-term extension	25
Rotational thromboelastometry (ROTEM) profiling of COVID–19 patients	25
Platelets and viruses	22
Release of α-granule contents during platelet activation	22
Application of Platelet Rich Fibrin in Tissue Engineering: Focus on Bone Regeneration	22
Extensive characterization of the composition and functional activities of five preparations of human platelet lysates for dedicated clinical uses	21
Human platelet lysates for human cell propagation	21
The structure of CLEC-2: mechanisms of dimerization and higher-order clustering	20
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	20
Bioinspired artificial platelets: past, present and future	18
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	18
Platelet–leukocyte interactions in the pathogenesis of viral infections	18
Immobilized collagen prevents shedding and induces sustained GPVI clustering and signaling in platelets	17
Diagnostic and prognostic role of platelets in patients with sepsis and septic shock	17

Structure-function relationship of the platelet glycoprotein VI (GPVI) receptor: does it matter if it is a dimer or monomer?	16
Cytosolic and mitochondrial Ca²⁺ signaling in procoagulant platelets	16
Platelets in dengue infection: more than a numbers game	16
Zinc: an endogenous and exogenous regulator of platelet function during hemostasis and thrombosis	15
The efficacy and safety of thrombopoietin receptor agonists in patients with chronic liver disease undergoing elective procedures: a systematic review and meta-analysis	15
Alterations in platelets during SARS-CoV-2 infection	15
Prevalence and natural history of variants in the ANKRD26 gene: a short review and update of reported cases	14
Platelet reticulated forms, size indexes and functional activity. Interactions in healthy volunteers.	14
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	14
Severe thrombocytopenia in adults undergoing extracorporeal membrane oxygenation is predictive of thrombosis	14
Frozen and cold-stored platelets: reconsidered platelet products	14
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function	13
EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling	13
Sex differences in antiplatelet therapy: state-of-the art	13
Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B	13
Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets	13
Left ventricular assist device implantation causes platelet dysfunction and proinflammatory platelet-neutrophil interaction	13
Signaling mechanisms of the platelet glycoprotein Ib-IX complex	12
Differential effect of clopidogrel and ticagrelor on leukocyte count in relation to patient characteristics, biomarkers and genotype: a PLATO substudy	12
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	12
Platelet Function Assays for the Diagnosis of Aspirin Resistance	12
Platelet activation by charged ligands and nanoparticles: platelet glycoprotein receptors as pattern recognition receptors	12
Efficacy and safety of eltrombopag in Chinese patients with chronic immune thrombocytopenia: stage 2 results from a multicenter phase III study	12
Platelet-derived microparticles stimulated by anti-β ₂ GPI/β ₂ GPI complexes induce pyroptosis of endothelial cells in antiphospho	12
Overcoming challenges in developing small molecule inhibitors for GPVI and CLEC-2	11
GPIb-IX-V and platelet clearance	11
Antiplatelet drugs and liver fibrosis	11
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	11
Distribution and quantification of activated platelets in platelet-rich fibrin matrices	10
The enigmatic nature of the triggering receptor expressed in myeloid cells -1 (TLT- 1)	10
Thrombocytopenia and platelet count recovery in patients with sepsis-3: a retrospective observational study	10
Higher body mass index raises immature platelet count: potential contribution to obesity-related thrombosis	10
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	10
P2X1: a unique platelet receptor with a key role in thromboinflammation	10
Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation	10
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans	10
Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and convalescent phase of COVID-19	10
Injectable platelet-rich fibrin positively regulates osteogenic differentiation of stem cells from implant hole via the ERK1/2 pathway	10
A proprietary GMP human platelet lysate for the expansion of dermal fibroblasts for clinical applications	9
Evolution of platelet activation parameters during septic shock in intensive care unit	8
Why do platelets express K⁺ channels?	8
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of BMS-986141, a novel, reversible, small-molecule, PAR4 agonist in non-Japanese and Japanese healthy participants	8
Association between platelet counts and morbidity and mortality after endovascular repair for type B aortic dissection	8
Management of immune thrombotic thrombocytopenic purpura with caplacizumab: a Canadian, single-centre, real-world experience	8
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	8
Platelet extracellular vesicles are efficient delivery vehicles of doxorubicin, an anti-cancer drug: preparation and in vitro characterization	8
The role of viscoelastic testing in assessing peri-interventional platelet function and coagulation	8
Ionotropic glutamate receptors in platelets: opposing effects and a unifying hypothesis	8
Complement activation negatively affects the platelet response to thrombopoietin receptor agonists in patients with immune thrombocytopenia: a prospective cohort study	7
Platelet-leukocyte aggregate formation and inflammation in patients with pulmonary arterial hypertension and CTEPH	7

Recovery of platelet reactivity following cessation of either aspirin or ticagrelor in patients treated with dual antiplatelet therapy following percutaneous coronary intervention: a GLOBAL LEADERS su	7
Platelets: bridging thrombosis and inflammation	7
Refractory immune thrombocytopenia successfully treated with bortezomib in a child with 22q11.2 deletion syndrome, complicated by Evans syndrome and hypogammaglobulinemia	7
Platelet activation and aggregation in different centrifugal-flow left ventricular assist devices	7
Circulating microRNAs as biomarkers and mediators of platelet activation	7
Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes	7
Pathogen inactivation of platelets for transfusion	7
Mean platelet volume: a prognostic marker in heart failure with preserved ejection fraction	7
Human Platelets and Influenza Virus: Internalization and Platelet Activation	7
Effect of leukocyte-platelet fibrin-rich wound reconstruction followed by full-thickness skin grafting in the treatment of diabetic foot Wagner grade 4 ulcer gangrene (toe area)	7
Enrichment of plasma in platelets and extracellular vesicles by the counterflow to erythrocyte settling	7
The efficacy of platelet rich plasma on anterior cruciate ligament reconstruction: a systematic review and meta-analysis	7
New presentations and exacerbations of immune thrombocytopenia after coronavirus disease 2019 vaccinations: the Taiwan experience	7
Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study	7
Reply to “Peripheral versus central venous blood sampling does not influence the assessment of platelet activation in cirrhosis”	7
Helicobacter pylori protein that binds to and activates platelet specifically reacts with sera of H. pylori-associated chronic immune thrombocytopenia	7
Relationship between Hepatitis B virus infection and platelet production and dysfunction	7
Is the endogenous ligand for PEAR1 a proteoglycan: clues from the sea	7
Whole blood platelet aggregation measurement by Multiplate™: potential diagnostic inaccuracy of correcting the results for the sample platelet count	7
The potency of selatogrel, a reversible antagonist of the P2Y12 receptor, is affected by calcium concentration	7