OOIR: Observatory of International Research

Papers

(The TQCC of Platelets is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Platelets editorial 2022: transitioning	37
Enrichment of plasma in platelets and extracellular vesicles by the counterflow to erythrocyte settling	35
Proteomics-wise, how similar are mouse and human platelets?	30
Stability and utility of flow cytometric platelet activation tests: A modality to bridge the gap between diagnostic demand and supply	27
New αIIbβ3 variants in 28 Turkish Glanzmann patients; structural hypothesis for complex activation by residues variations in I-EGF domains	25
Nebulization with alkaline hipertonic ibuprofen induces a rapid increase in platelets circulating in COVID-19 patients but not in healthy subjects	22
Arachidonic acid-induced platelet aggregation and acetylsalicylic acid treatment during pregnancy in women with recurrent miscarriage, a post hoc study	22
Thrombosis and hemorrhage in myeloproliferative neoplasms: The platelet perspective	22
Frequency and molecular basis of CD36 deficiency among platelet donors in Kunming, China	20
Trends among platelet function, arterial calcium, and vascular function measures	20
Thrombus remodelling by reversible and irreversible P2Y ₁₂ inhibitors	20
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	18
Predictive performance of different bleeding risk scores in patients with atrial fibrillation and acute coronary syndrome or undergoing percutaneous coronary intervention	18
The utility of flow cytometric platelet forward scatter as an alternative to mean platelet volume	17
Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation	17
Platelet–leukocyte interactions in the pathogenesis of viral infections	16
Contributing role of mitochondrial energy metabolism on platelet adhesion, activation and thrombus formation under blood flow conditions	16
High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients	16
Platelet activation and aggregation in different centrifugal-flow left ventricular assist devices	14
The complementary roles of VAMP-2, -3, and -7 in platelet secretion and function	14
Thrombocytopenia and platelet count recovery in patients with sepsis-3: a retrospective observational study	14
EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling	14
Prostacyclin analogues decrease platelet aggregation but have no effect on thrombin generation, fibrin clot structure, and fibrinolysis in pulmonary arterial hypertension: PAPAYA coagulation	14
The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model	14
Factors influencing platelet isolation: a prospective multicenter study from Western China	13

Immunological platelet transfusion refractoriness: current insights from mechanisms to therapeutics	13
What can the plasma proteome tell us about platelets (and vice versa)?	13
Comparison of predictive value of risk scores for gastrointestinal bleeding in antiplatelet therapy	13
Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients	13
Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets	13
How can we use proteomics to learn more about platelets?	13
The potential utilization of platelet-derived extracellular vesicles in clinical treatment	12
The safety and efficacy of indobufen or aspirin combined with clopidogrel in patients with acute myocardial infarction after percutaneous coronary intervention	12
Activation of AMPK in platelets promotes the production of offspring	12
Finding and following: a deep learning-based pipeline for tracking platelets during thrombus formation in vivo and ex vivo	12
Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents	12
Molecular insights on Eltrombopag: potential mitogen stimulants, angiogenesis, and therapeutic radioprotectant through TPO-R activation	11
Effects of different doses of tirofiban combined with dual antiplatelet drugs on platelet indices, vascular endothelial function, and major adverse cardiovascular events in patients with acute ST-segm	11
Real-life clinical practice in Spain in the setting of new drug availability for ITP treatment. A Delphi-based Spanish expert panel consensus	11
Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets	10
GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction	10
EloA promotes HEL polyploidization upon PMA stimulation through enhanced ERK1/2 activity	10
Frozen and cold-stored platelets: reconsidered platelet products	10
Development of an automated chemiluminescence enzyme immunoassay for the measurement of soluble C-type lectin-like receptor 2 (sCLEC-2) and molecular forms of sCLEC-2 measured in patient plasma	10
Effect of iron supplementation on platelet count in adult patients with iron deficiency anemia	10
The Total Thrombus Formation (T-TAS) platelet (PL) assay, a novel test that evaluates whole blood platelet thrombus formation under physiological conditions	10
Effects of electret coating technology on coronary stent thrombogenicity	10
Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation	9
Platelet-derived microparticles stimulated by anti-β ₂ GPI/β ₂ GPI complexes induce pyroptosis of endothelial cells in antiphospho	8
Efficacy and safety of abciximab versus tirofiban in addition to ticagrelor in STEMI patients undergoing primary percutaneous intervention	8
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	8
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro	8
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of BMS-986141, a novel, reversible, small-molecule, PAR4 agonist in non-Japanese and Japanese healthy participants	8
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	8
A platelet lipidomics signature in patients with COVID-19	8
What can we learn from senescent platelets, their transcriptomes and proteomes?	8
Efficacy of platelet transfusion in cardiac surgery	8
Neonatal platelet physiology and implications for transfusion	7
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	7
Successful mRNA SARS-Cov-2 vaccine rechallenge after a first episode of immune thrombocytopenic purpura	7
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	7
Vaccine-induced immune thrombotic thrombocytopenia in a male after Ad26.COV2.S vaccination presenting as cerebral venous sinus thrombosis	7
Rivaroxaban reduces thromboxane induced platelet aggregation - the forgotten compass arm?	7
Healthy pediatric platelets are moderately hyporeactive in comparison with adults’ platelets	7
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy	7
Cardiometabolic risk factor burden associates with an immature platelet profile	7
Injectable platelet-rich fibrin positively regulates osteogenic differentiation of stem cells from implant hole via the ERK1/2 pathway	7
Platelets and viruses	7
Crushed/chewed administration of potent P2Y₁₂ inhibitors in ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: Systematic review and meta-anal	7
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	7
Immature platelets and cardiovascular events in patients with stable coronary artery disease	7
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	7
Prospective assessment of platelet function in patients undergoing elective resection of glioblastoma multiforme	7
The prospects of microphysiological systems in modeling platelet pathophysiology in cancer	7
Splenectomy in zebrafish: a new model for immune thrombocytopenia	7

Management of immune thrombotic thrombocytopenic purpura with caplacizumab: a Canadian, single-centre, real-world experience	7
The voltage-gated K⁺ channel Kv1.3 modulates platelet motility and α₂β₁ integrin-dependent adhesion to collagen	7
Predictors of high platelet reactivity assessed by Multiple Electrode Aggregometry in healthy individuals ‒ the role of leukocyte count	6
A novel RUNX1 exon 3 - 7 deletion causing a familial platelet disorder	6
Humanized mouse models for inherited thrombocytopenia studies	6
Congenital thrombocytopenia associated with a heterozygous variant in the MEIS1 gene encoding a transcription factor essential for megakaryopoiesis	6
Chronic immune thrombocytopenia in a child with X-linked agammaglobulinemia-an uncommon phenotype	6
Age and outcomes following personalized antiplatelet therapy in chronic coronary syndrome patients: a post hoc analysis of the randomized PATH-PCI trial	6
Anti-GPVI (HY101) activates platelets in a multicolor flow cytometry panel	6
Decreased platelet miR-199a-5p level might lead to high on-clopidogrel platelet reactivity in patients with coronary artery disease	6
Scanning transmission X-ray microscopy study of subcellular granules in human platelets at the carbon K- and calcium L2,3-edges	6
Editorial: structure–function relationships of tyrosine kinase- and tyrosine phosphatase-linked receptors in platelets and megakaryocytes	6
Treatment of immune thrombocytopenia with hetrombopag olamine tablets in a Kabuki syndrome patient with new KMT2D mutations	6
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia	6
Analysis of clinical characteristics and treatment efficacy in two pediatric cases of ANKRD26 -related thrombocytopenia	6
Mutated JAK2 signal transduction in human induced pluripotent stem cell (iPSC)-derived megakaryocytes	6