Platelets

Article	Citations
Association between platelet parameters and mortality in coronavirus disease 2019: Retrospective cohort study	196
Prediction of severe illness due to COVID-19 based on an analysis of initial Fibrinogen to Albumin Ratio and Platelet count	109
Immunothrombosis and thromboinflammation in host defense and disease	82
Hemostatic laboratory derangements in COVID-19 with a focus on platelet count	61
Platelet functions and activities as potential hematologic parameters related to Coronavirus Disease 2019 (Covid-19)	60
A proof of evidence supporting abnormal immunothrombosis in severe COVID-19: naked megakaryocyte nuclei increase in the bone marrow and lungs of critically ill patients	50
Platelet Rich Plasma in Orthopedic Surgical Medicine.	40
Histological comparison of Platelet rich fibrin clots prepared by fixed-angle versus horizontal centrifugation	36
PRP in wound healing applications	34
Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity	33
A rationale for blocking thromboinflammation in COVID-19 with Btk inhibitors	33
Technical and biological review of authorized medical devices for platelets-rich plasma preparation in the field of regenerative medicine	32
Cerebral venous sinus thrombosis associated with spontaneous heparin-induced thrombocytopenia syndrome after total knee arthroplasty	30
Platelet rich plasma in oral and maxillofacial surgery from the perspective of composition	29
Role of platelets and megakaryocytes in adaptive immunity	28
Search for SARS-CoV-2 RNA in platelets from COVID-19 patients	28
Thrombus heterogeneity in ischemic stroke	28
In vivo evaluation of the biocompatibility and biodegradation of a new denatured plasma membrane combined with liquid PRF (Alb-PRF)	28
Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases	27
Over time relationship between platelet reactivity, myocardial injury and mortality in patients with SARS-CoV-2-associated respiratory failure	26
Rotational thromboelastometry (ROTEM) profiling of COVID–19 patients	24
The thrombopoietin receptor: revisiting the master regulator of platelet production	23
Thrombopoietin receptor agonists for the treatment of primary immune thrombocytopenia: a meta-analysis and systematic review	22
Efficacy and safety evaluation of avatrombopag in immune thrombocytopenia: analyses of a phase III study and long-term extension	21
Neonatal platelet physiology and implications for transfusion	21

Platelets and viruses	20
Risk of major adverse cardiovascular events of CYP2C19 loss-of-function genotype guided prasugrel/ticagrelor vs clopidogrel therapy for acute coronary syndrome patients undergoing percutaneous	20
Isolation of murine bone marrow by centrifugation or flushing for the analysis of hematopoietic cells – a comparative study	19
Platelet removal by single-step centrifugation	19
Platelet-rich plasma promotes bone formation, restrains adipogenesis and accelerates vascularization to relieve steroids-induced osteonecrosis of the femoral head	19
The structure of CLEC-2: mechanisms of dimerization and higher-order clustering	18
Application of Platelet Rich Fibrin in Tissue Engineering: Focus on Bone Regeneration	18
Human platelet lysates for human cell propagation	17
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	17
MicroRNA-126 is a regulator of platelet-supported thrombin generation	17
Extensive characterization of the composition and functional activities of five preparations of human platelet lysates for dedicated clinical uses	17
Platelets and renal failure in the SARS-CoV-2 syndrome	16
Mouse laser injury models: variations on a theme	16
Lymphatic blood filling in CLEC-2-deficient mouse models	16
Platelet–leukocyte interactions in the pathogenesis of viral infections	16
Novel antiplatelet targets in the treatment of acute coronary syndromes	16
Zinc regulates reactive oxygen species generation in platelets	16
Transient appearance of EDTA dependent pseudothrombocytopenia in a patient with 2019 novel coronavirus pneumonia	15
Bioinspired artificial platelets: past, present and future	15
Immobilized collagen prevents shedding and induces sustained GPVI clustering and signaling in platelets	15
Use of electron microscopy to study platelets and thrombi	14
An adaptable analysis workflow for characterization of platelet spreading and morphology	14
Changes in megakaryopoiesis over ontogeny and their implications in health and disease	13
Structure-function relationship of the platelet glycoprotein VI (GPVI) receptor: does it matter if it is a dimer or monomer?	13
Cytosolic and mitochondrial Ca2+ signaling in procoagulant platelets	13
The efficacy and safety of thrombopoietin receptor agonists in patients with chronic liver disease undergoing elective procedures: a systematic review and meta-analysis	13
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	12
Alterations in platelets during SARS-CoV-2 infection	12
EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling	12
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	12
Efficacy and safety of eltrombopag in Chinese patients with chronic immune thrombocytopenia: stage 2 results from a multicenter phase III study	12
Antiplatelet drugs and liver fibrosis	11
Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets	11
Left ventricular assist device implantation causes platelet dysfunction and proinflammatory platelet-neutrophil interaction	11
Frozen and cold-stored platelets: reconsidered platelet products	11
Platelet activation by charged ligands and nanoparticles: platelet glycoprotein receptors as pattern recognition receptors	11
Platelet-rich plasma loaded with antibiotics as an affiliated treatment for infected bone defect by combining wound healing property and antibacterial activity	11
Harmonizing light transmission aggregometry in the Netherlands by implementation of the SSC-ISTH guideline	11
Platelet count and function in umbilical cord blood versus peripheral blood in term neonates	11
Platelet reticulated forms, size indexes and functional activity. Interactions in healthy volunteers.	11
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	11
Studies on platelet rich plasma - new editorial policy for “Platelets”	11
Diagnostic and prognostic role of platelets in patients with sepsis and septic shock	10
Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B	10
In vitro-derived platelets: the challenges we will have to face to assess quality and safety	10
Release of α-granule contents during platelet activation	10
ABCG5 and ABCG8 gene variations associated with sitosterolemia and platelet dysfunction	10
Thrombocytopenia and platelet count recovery in patients with sepsis-3: a retrospective observational study	10
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function	10
Impact of high on-treatment platelet reactivity after angioplasty in patients with peripheral arterial disease	10

Platelet-derived microparticles stimulated by anti-β 2 GPI/β 2 GPI complexes induce pyroptosis of endothelial cells in antiphospho	10
Overcoming challenges in developing small molecule inhibitors for GPVI and CLEC-2	9
Immature platelet indices alongside procalcitonin for sensitive and specific identification of bacteremia in the intensive care unit	9
Selective inhibition of thromboinflammation in COVID-19 by Btk inhibitors	9
Platelet Function Assays for the Diagnosis of Aspirin Resistance	9
Severe thrombocytopenia in adults undergoing extracorporeal membrane oxygenation is predictive of thrombosis	9
Mechanisms of platelet release: in vivo studies and in vitro modeling	9
High extracellular phosphate increases platelet polyphosphate content	9
Differential effect of clopidogrel and ticagrelor on leukocyte count in relation to patient characteristics, biomarkers and genotype: a PLATO substudy	9
A proprietary GMP human platelet lysate for the expansion of dermal fibroblasts for clinical applications	9
Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and convalescent phase of COVID-19	9
Zinc: an endogenous and exogenous regulator of platelet function during hemostasis and thrombosis	9
Higher body mass index raises immature platelet count: potential contribution to obesity-related thrombosis	9
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	8
Platelets in dengue infection: more than a numbers game	8
High-efficiency unassisted transfection of platelets with naked double-stranded miRNAs modulates signal-activated translation and platelet function	8
The enigmatic nature of the triggering receptor expressed in myeloid cells -1 (TLT- 1)	8
Factor Xa and thrombin induce endothelial progenitor cell activation. The effect of direct oral anticoagulants	8
The efficacy and safety of CYP2C19 genotype-guided antiplatelet therapy compared with conventional antiplatelet therapy in patients with acute coronary syndrome or undergoing percutaneous coronary int	8
Prevalence and natural history of variants in the ANKRD26 gene: a short review and update of reported cases	8
Effect of differently coated silver nanoparticles on hemostasis	8
Whole blood flow cytometry protocol for the assessment of platelet phenotype, function, and cellular interactions	8
Investigation of fibrinogen in early bleeding of patients with newly diagnosed acute promyelocytic leukemia	8
Refractory immune thrombocytopenia successfully treated with bortezomib in a child with 22q11.2 deletion syndrome, complicated by Evans syndrome and hypogammaglobulinemia	7
Prognostic significance of thrombocytosis in lung cancer: a systematic review and meta-analysis	7
Recovery of platelet reactivity following cessation of either aspirin or ticagrelor in patients treated with dual antiplatelet therapy following percutaneous coronary intervention: a GLOBAL LEADERS su	7
Pathogen inactivation of platelets for transfusion	7
Platelets: bridging thrombosis and inflammation	7
Enrichment of plasma in platelets and extracellular vesicles by the counterflow to erythrocyte settling	7
Statins potentiate the antibacterial effect of platelets on Staphylococcus aureus	7
The potency of selatogrel, a reversible antagonist of the P2Y12 receptor, is affected by calcium concentration	7
Association of lipoprotein(a) with platelet aggregation and thrombogenicity in patients undergoing percutaneous coronary intervention	7
GPIb-IX-V and platelet clearance	7
Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study	7
P2X1: a unique platelet receptor with a key role in thromboinflammation	7
Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape	7
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	7
Evolution of platelet activation parameters during septic shock in intensive care unit	7
New presentations and exacerbations of immune thrombocytopenia after coronavirus disease 2019 vaccinations: the Taiwan experience	7
The Influence of Prostaglandin E1 and Use of Inhibitor Percentage on the Correlation between the Multiplate and VerifyNow in Patients on Dual Antiplatelet Therapy	7
Injectable platelet-rich fibrin positively regulates osteogenic differentiation of stem cells from implant hole via the ERK1/2 pathway	7
The basement membrane protein nidogen-1 supports platelet adhesion and activation	7
Optimized tool for evaluation of platelet function measured by impedance aggregometry	7
FLNA variants associated with disorders of platelet number or function	6
Ticagrelor versus clopidogrel for prevention of subclinical stent thrombosis detected by optical coherence tomography in patients with drug-eluting stent implantation—a multicenter and randomized stud	6
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans	6
The role of viscoelastic testing in assessing peri-interventional platelet function and coagulation	6
Why do platelets express K+ channels?	6
Novel antiplatelet strategies targeting VWF and GPIb	6
Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation	6
Exacerbation of immune thrombocytopenia following initial and booster vaccination with Pfizer-BioNTech COVID-19 vaccine	6
Reply to “Peripheral versus central venous blood sampling does not influence the assessment of platelet activation in cirrhosis”	6
Helicobacter pylori protein that binds to and activates platelet specifically reacts with sera of H. pylori-associated chronic immune thrombocytopenia	6
Human Platelets and Influenza Virus: Internalization and Platelet Activation	6
A new player in the game: platelet-derived extracellular vesicles in dengue hemorrhagic fever	6
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	6
Signaling mechanisms of the platelet glycoprotein Ib-IX complex	6
Circulating microRNAs as biomarkers and mediators of platelet activation	6
Distribution and quantification of activated platelets in platelet-rich fibrin matrices	6
Comparison of antiplatelet antibody profiles between hepatitis C virus-associated immune thrombocytopenia and primary immune thrombocytopenia	6
Platelet activation and aggregation in different centrifugal-flow left ventricular assist devices	6
Sex differences in antiplatelet therapy: state-of-the art	5
Marginal band microtubules are acetylated by αTAT1	5
Reference values for thrombin dynamics in platelet rich plasma	5
Improvement of platelet in thrombocytopenic HCV patients after treatment with direct-acting antiviral agents and its relation to outcome	5
PTGS1 gene variations associated with bleeding and platelet dysfunction	5
Is the endogenous ligand for PEAR1 a proteoglycan: clues from the sea	5
Innate immune TLR7 signaling mediates platelet activation and platelet-leukocyte aggregate formation in murine bacterial sepsis	5
Catastrophic antiphospholipid syndrome refractory to high-dose intravenous immunoglobulin responsive to therapeutic plasma exchange	5
Method article: anin vitroblood flow model to advance the study of platelet adhesion utilizing a damaged endothelium	5
Peripheral versus central venous blood sampling does not influence the assessment of platelet activation in cirrhosis	5
Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength	5
Association between platelet counts and morbidity and mortality after endovascular repair for type B aortic dissection	5
Flow cytometry identifies an early stage of platelet apoptosis produced by agonists of the P2X1 and P2X7 receptors	5
Antiplatelet activity of astaxanthin in control- and high cholesterol-fed rats mediated by down-regulation of P2Y12, inhibition of NF-κB, and increasing intracellular levels of cAMP	5
Potential contrasting effects of platelets on the migration and invasion of sarcomas versus carcinomas	5
A handshake between platelets and neutrophils might fuel deep vein thrombosis	5
Relationship between Hepatitis B virus infection and platelet production and dysfunction	5
Whole blood platelet aggregation measurement by Multiplate™: potential diagnostic inaccuracy of correcting the results for the sample platelet count	5
Fatal cerebral hemorrhage in a patient with thrombotic thrombocytopenic purpura with a normal platelet count during treatment with caplacizumab	5

Platelet-leukocyte aggregate formation and inflammation in patients with pulmonary arterial hypertension and CTEPH	5
Effect of avatrombopag in the management of severe and refractory chemotherapy-induced thrombocytopenia (CIT) in patients with solid tumors	5
Influence of diagnosis of venous thromboembolism on immature platelets, absolute platelet count and platelet aggregation over time	5
Irradiation of platelets in transfusion medicine: risk and benefit judgments	5
Successful mRNA SARS-Cov-2 vaccine rechallenge after a first episode of immune thrombocytopenic purpura	5
Efficacy of platelet transfusion in cardiac surgery	5
Effects of leukocyte-rich platelet-rich plasma and leukocyte-poor platelet-rich plasma on the healing of bone-tendon interface of rotator cuff in a mice model	5
Platelet count and disease – editorial policy	5
Complement activation negatively affects the platelet response to thrombopoietin receptor agonists in patients with immune thrombocytopenia: a prospective cohort study	5
The effect of platelet-rich plasma injection on chronic Achilles tendinopathy and acute Achilles tendon rupture	5
ADP-induced platelet reactivity and bleeding events in patients with acute myocardial infarction complicated by cardiogenic shock	4
Management of immune thrombotic thrombocytopenic purpura with caplacizumab: a Canadian, single-centre, real-world experience	4
Use of rotational thromboelastometry for a global screening of coagulation profile in patients of myeloproliferative neoplasms	4
Comparison of the effects of platelet concentrates produced by high and low-speed centrifugation protocols on the healing of critical-size defects in rat calvaria: a microtomographic and histomorphome	4
Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients	4
“Tailored” antiplatelet bridging therapy with cangrelor: moving toward personalized medicine	4
A new case with Hermansky-Pudlak syndrome type 9, a rare cause of syndromic albinism with severe defect of platelets dense bodies	4
Potential biomarkers for inherited thrombocytopenia 2 identified by plasma proteomics	4
Profile of reticulated platelets in the early, subacute and late phases after transient ischemic attack or ischemic stroke	4
Effects of remote ischemic preconditioning on platelet activation and reactivity in patients undergoing cardiac surgery using cardiopulmonary bypass: a randomized controlled trial	4
Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study	4
Mind the gap: connexins and pannexins in platelet function	4
ETV6-related thrombocytopenia and platelet dysfunction	4
Platelet glycogenolysis is important for energy production and function	4
The utility of platelet activation biomarkers in thrombotic microangiopathies	4
Benefit-risk profile of extended dual antiplatelet therapy beyond 1 year in patients with high risk of ischemic or bleeding events after PCI	4
Platelet parameters and risk of hypertension disorders of pregnancy: a propensity score adjusted analysis	4
The Total Thrombus Formation (T-TAS) platelet (PL) assay, a novel test that evaluates whole blood platelet thrombus formation under physiological conditions	4
Treatment of immune thrombocytopenia (ITP) secondary to malignancy: a systematic review	4
Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes	4
Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure	4
Pre-operative platelet reactivity is a strong, independent predictor of bleeding complications after branched endovascular thoracoabdominal aortic aneurysm repair	4
Aquaporins in platelet function	4
A novel RUNX1 exon 3 - 7 deletion causing a familial platelet disorder	4
Current challenges in platelet transfusion	4
Effect of iron supplementation on platelet count in adult patients with iron deficiency anemia	4
Immature platelets in COVID-19	4
Ionotropic glutamate receptors in platelets: opposing effects and a unifying hypothesis	4
The efficacy of platelet rich plasma on anterior cruciate ligament reconstruction: a systematic review and meta-analysis	4
Platelet count and risk of major bleeding in venous thromboembolism	4
Mean platelet volume: a prognostic marker in heart failure with preserved ejection fraction	4
Hemostasis-on-a-chip / incorporating the endothelium in microfluidic models of bleeding	4
Pro-apoptotic properties and mitochondrial functionality in platelet-like-particles generated from low Aspirin-incubated Meg-01 cells	4
High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on αIIbβ3 and platelet secretion	3
Effects of electret coating technology on coronary stent thrombogenicity	3
Whole blood dynamic platelet aggregation counting and 1-year clinical outcomes in patients with coronary heart diseases treated with clopidogrel	3
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	3
Effect of leukocyte-platelet fibrin-rich wound reconstruction followed by full-thickness skin grafting in the treatment of diabetic foot Wagner grade 4 ulcer gangrene (toe area)	3
Reversible cross-tolerance to platelet-activating factor signaling by bacterial toxins	3
Rapid isolation of mature murine primary megakaryocytes by size exclusion via filtration	3
Not-high before-treatment platelet reactivity in patients with STEMI: prevalence, clinical characteristics, response to therapy and outcomes	3
Hiding in plain sight – platelets, the silent carriers of HIV-1	3
Risk stratification and outcomes of intracranial hemorrhage in patients with immune thrombocytopenia under 60 years of age	3
Effect of platelet inhibitors on thrombus burden in patients with acute pulmonary embolism	3
Feasibility of a mean platelet volume standard: an international council for standardization in hematology (ICSH) inter-laboratory study	3
An optimized agonist peptide of protease-activated receptor 4 and its use in a validated platelet-aggregation assay	3
Effects of platelets activated by different agonists on fibrin formation and thrombin generation	3
Acquired platelet defect associated with gabapentin treatment: a case-report	3
Determination of fibrin clot growth and spatial thrombin propagation in the presence of different types of phospholipid surfaces	3
Efficacy and safety of abciximab versus tirofiban in addition to ticagrelor in STEMI patients undergoing primary percutaneous intervention	3
Intravital imaging of megakaryocytes	3
Platelet surface GPIbα, activated GPIIb-IIIa, and P-selectin levels in adult veno-arterial extracorporeal membrane oxygenation patients	3
Does hsa-miR-223-3p from platelet-derived extracellular vesicles regulate tissue factor expression in monocytic cells?	3
Thrombus remodelling by reversible and irreversible P2Y 12 inhibitors	3
Correlation of CLEC1B haplotypes with plasma levels of soluble CLEC-2 in healthy individuals	3
Sex differences in platelet reactivity in patients with myocardial infarction treated with triple antiplatelet therapy - results from assessing platelet activity in coronary heart disease (APACHE)	3
Romiplostim for PARP inhibitor-induced thrombocytopenia in solid tumor malignancies	3
Severe thrombocytopenia and intracranial hemorrhage in a newborn with Noonan syndrome and neonatal alloimmune thrombocytopenia	3
Platelets get gutted by PAG	3
Platelets after burn injury – hemostasis and beyond	3
Evening aspirin intake results in higher levels of platelet inhibition and a reduction in reticulated platelets - a window of opportunity for patients with cardiovascular disease?	3
Successful treatment of acquired amegakaryocytic thrombocytopenia with eltrombopag and immunosuppressant	3
Healthy pediatric platelets are moderately hyporeactive in comparison with adults’ platelets	3
Eltrombopag modulates the phenotypic evolution and potential immunomodulatory roles of monocytes/macrophages in immune thrombocytopenia	3
What can we learn from senescent platelets, their transcriptomes and proteomes?	3
A novel frameshiftGP1BBmutation causes autosomal dominant macrothrombocytopenia with decreased vWF receptor expression but normal platelet aggregation	3
Absence of bleeding upon dual antiplatelet therapy in a patient with a immune GPVI deficiency	3
Actin polymerization regulates glycoprotein Ibα shedding	3
Mapping densely packed αIIbβ3 receptors in murine blood platelets with expansion microscopy	3
Inflammatory state does not affect the antiplatelet efficacy of potent P2Y12 inhibitors in ACS	3
EDI(torial): equality, diversity, and inclusion and platelets - 2021	3
Revisiting the management of chronic ITP; a randomized controlled clinical trial	3
Evaluating stored platelet shape change using imaging flow cytometry	3
Building platelet phenotypes: Diaphanous-related formin 1 (DIAPH1)-related disorder	3
Thrombocytopathy vs Platelet hyper-reactivity in COVID-19: diverse pathologies, disease outcomes and therapeutic implications	3