Platelets

Article	Citations
Comparison of predictive value of risk scores for gastrointestinal bleeding in antiplatelet therapy	52
Contributing role of mitochondrial energy metabolism on platelet adhesion, activation and thrombus formation under blood flow conditions	44
High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients	33
Prostacyclin analogues decrease platelet aggregation but have no effect on thrombin generation, fibrin clot structure, and fibrinolysis in pulmonary arterial hypertension: PAPAYA coagulation	32
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	27
Predictive performance of different bleeding risk scores in patients with atrial fibrillation and acute coronary syndrome or undergoing percutaneous coronary intervention	26
Platelet-derived microparticles stimulated by anti-β 2 GPI/β 2 GPI complexes induce pyroptosis of endothelial cells in antiphospho	25
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	23
Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents	22
Trends among platelet function, arterial calcium, and vascular function measures	21
Development of an automated chemiluminescence enzyme immunoassay for the measurement of soluble C-type lectin-like receptor 2 (sCLEC-2) and molecular forms of sCLEC-2 measured in patient plasma	21
Sex-specific relationship between blood selenium levels and platelet count in a large cohort representative of the United States population	20
How can we use proteomics to learn more about platelets?	20
The natural anticoagulant protein S; hemostatic functions and deficiency	20
Clinical features and treatment effect of HIV-associated immune thrombocytopenia—single center Ten-Years data summary	19
Increased circulating platelet-derived extracellular vesicles in severe COVID-19 disease	18
Chronic immune thrombocytopenia in a child with X-linked agammaglobulinemia-an uncommon phenotype	17
Platelets and open access – a new era dawns	17
Bioinspired artificial platelets: past, present and future	17
Pro106Leu MPL mutation is associated with thrombocytosis and a low risk of thrombosis, splenomegaly and marrow fibrosis	16
Dual antiplatelet therapy is associated with high α-tubulin acetylation in circulating platelets from coronary artery disease patients	16
Crushed/chewed administration of potent P2Y12 inhibitors in ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: Systematic review and meta-anal	16
Effects of exercise on platelet reactivity after myocardial infarction: a randomized clinical trial	15
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function	15
Pre-operative platelet reactivity is a strong, independent predictor of bleeding complications after branched endovascular thoracoabdominal aortic aneurysm repair	15

Potential mechanisms involved on how systemic IgG antibodies specific to vascular endothelial growth factor (VEGF) and induced by active immunotherapy decrease platelet derived free-VEGF	14
Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study	14
Extracellular thiol isomerase ERp5 regulates integrin αIIbβ3 activation by inhibition of fibrinogen binding	14
Significance of mild thrombocytopenia in maintenance hemodialysis patients; a retrospective cohort study	14
European Delphi panel to build consensus on tapering and discontinuing thrombopoietin receptor agonists in immune thrombocytopenia	14
Association between megakaryocyte abnormalities on bone marrow smear and response to thrombopoietin receptor agonists in adult patients with primary immune thrombocytopenia	14
Pathogen inactivation of platelets for transfusion	13
Variation in activation marker expression within the platelet population – a new parameter for evaluation of platelet flow cytometry data	13
Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets	12
Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets	12
Platelet response to aspirin in UK and Irish pregnancy cohorts: a genome-wide approach	12
Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation	12
Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength	12
Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure	12
Potential and limitations of PKA/ PKG inhibitors for platelet studies	11
Ion channels and ion homeostasis in the platelet and megakaryocyte	11
Recent advances in microfluidic technology of arterial thrombosis investigations	10
The efficacy of platelet rich plasma on anterior cruciate ligament reconstruction: a systematic review and meta-analysis	10
Inflammation modifies the platelet reactivity among thrombocytopenia patients undergoing percutaneous coronary intervention	10
Circulating microRNAs as biomarkers and mediators of platelet activation	10
Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes	10
In memory of Dr. Susan S. Smyth, MD/Ph.D.	9
A splice mutation in RASGRP2 gene in the patient with recurrent epistaxis and nasal vascular malformation	9
Evolution of platelet activation parameters during septic shock in intensive care unit	9
Neurosurgical bleeding in platelet storage pool disorder: a case report	9
Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets	9
Association of thromboxane generation with the bleeding events in aspirin users	9
Platelets in dengue infection: more than a numbers game	9
Impact of thrombocytopenia-associated c.-118C>T and c.-140C>G ANKRD26 5’UTR variants in three-generational pedigree	9
Role of platelet count in a murine stasis model of deep vein thrombosis	8
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro	8
Thrombosis and hemorrhage in myeloproliferative neoplasms: The platelet perspective	8
miR-28-5p targeted Rap1b attenuates splenic inflammation infiltration in immune thrombocytopenia	8
Higher body mass index raises immature platelet count: potential contribution to obesity-related thrombosis	8
What can we learn from senescent platelets, their transcriptomes and proteomes?	8
Cardiometabolic risk factor burden associates with an immature platelet profile	8
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy	8
Factors influencing platelet isolation: a prospective multicenter study from Western China	8
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	8
EloA promotes HEL polyploidization upon PMA stimulation through enhanced ERK1/2 activity	8
Efficacy and safety of two rituximab biosimilars for treating immune thrombocytopenia: a reference-product matched study	7
Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets	7
Congenital thrombocytopenia associated with a heterozygous variant in the MEIS1 gene encoding a transcription factor essential for megakaryopoiesis	7
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	7
Thrombocytopathy vs Platelet hyper-reactivity in COVID-19: diverse pathologies, disease outcomes and therapeutic implications	7
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	7
The safety and efficacy of indobufen or aspirin combined with clopidogrel in patients with acute myocardial infarction after percutaneous coronary intervention	7
Multiple myeloma and its treatment contribute to increased platelet reactivity	7
Age and outcomes following personalized antiplatelet therapy in chronic coronary syndrome patients: a post hoc analysis of the randomized PATH-PCI trial	7
Q94 is not a selective modulator of proteinase-activated receptor 1 (PAR1) in platelets	7

Frozen and cold-stored platelets: reconsidered platelet products	7
Editorial: structure–function relationships of tyrosine kinase- and tyrosine phosphatase-linked receptors in platelets and megakaryocytes	7
Additional efficacy analysis of avatrombopag phase III data for the treatment of adults with immune thrombocytopenia	7
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	7
Evaluating stored platelet shape change using imaging flow cytometry	7
Association between endometriosis, infertility and autoimmune antiplatelet glycoprotein VI antibodies in two patients	6
Platelet counts in HFE p.C282Y/p.C282Y and wt/wt post-screening clinical evaluation participants	6
Positive correlations between plasma BPI level and MPO-DNA and S100A8/A9 in myocardial infarction	6
Effect of avatrombopag in the management of severe and refractory chemotherapy-induced thrombocytopenia (CIT) in patients with solid tumors	6
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans	6
Feasibility of platelet marker analysis in ischemic stroke patients and their association with one-year outcome. A pilot project within a subsample of the Stroke Induced Cardiac Failure in Mice and Me	6
Romiplostim for PARP inhibitor-induced thrombocytopenia in solid tumor malignancies	6
Alterations in platelets during SARS-CoV-2 infection	6
Cryopreservation affects platelet macromolecular composition over time after thawing and differently impacts on cancer cells behavior in vitro	6
Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP	6
Alantolactone induces platelet apoptosis by activating the Akt pathway	6
Platelet index on admission as a predictor of bacteremia in acute cholangitis: a 7-year retrospective observational study	6
A novel, quantitative clot retraction assay to evaluate platelet function	6
Appraising non-linear association between pre-diagnostic platelet counts and cancer survival outcomes: observational and genetic analysis	6
Correlations among different platelet aggregation pathways in a group of healthy volunteers	5
Antiplatelet effects of the CEACAM1-derived peptide QDTT	5
Introduction of direct-acting antiviral agents alters frequencies of anti-GPIIb/IIIa antibody-producing B cells in chronic hepatitis C patients with thrombocytopenia	5
An oligogenic case of severe neonatal thrombocytopenia and a purportedly benign variant in GFI1B requiring reinterpretation	5
Exacerbation of immune thrombocytopenia following initial and booster vaccination with Pfizer-BioNTech COVID-19 vaccine	5
Platelet parameters for distinguishing between inherited macrothrombocytopenia and acquired thrombocytopenia: a retrospective case–control study	5
How can platelet proteomics best be used to interrogate disease?	5
Platelet extracellular vesicles are efficient delivery vehicles of doxorubicin, an anti-cancer drug: preparation and in vitro characterization	5
Regulation of lipid metabolism: a new strategy for platelet storage	5
Role of the NO-GC/cGMP signaling pathway in platelet biomechanics	5
Whole blood platelet aggregation measurement by Multiplate™: potential diagnostic inaccuracy of correcting the results for the sample platelet count	5
Genetic background of thrombocytosis in mice mimicking hereditary thrombocytosis in humans	5
Current challenges in platelet transfusion	5
Correction	5
From reticulated platelets to immature platelet fraction: structure, function, and clinical applications	5
Differential effect of clopidogrel and ticagrelor on leukocyte count in relation to patient characteristics, biomarkers and genotype: a PLATO substudy	5
Optimizing the therapeutic window of sirolimus by monitoring blood concentration for the treatment of immune thrombocytopenia	5
The complementary roles of VAMP-2, -3, and -7 in platelet secretion and function	5
Mass cytometry of platelet-rich plasma: a new approach to analyze platelet surface expression and reactivity	5
Inhibition of platelet-activating factor (PAF)-induced platelet aggregation by fatty acids from human saliva	5
Mapping densely packed αIIbβ3 receptors in murine blood platelets with expansion microscopy	5
Rapid isolation of mature murine primary megakaryocytes by size exclusion via filtration	5
Platelet-HIV: interactions and their implications	5
Effect of iron supplementation on platelet count in adult patients with iron deficiency anemia	5
Performance evaluation of PLT-H (hybrid-channel platelet) under various interferences and application studies for platelet transfusion decisions	4
Decreased platelet miR-199a-5p level might lead to high on-clopidogrel platelet reactivity in patients with coronary artery disease	4
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	4
A case of acquired transient bleeding diathesis associated with acquired platelet storage pool deficiency and defective thromboxane A2 production	4
The role of viscoelastic testing in assessing peri-interventional platelet function and coagulation	4
Vaccine-induced immune thrombotic thrombocytopenia in a male after Ad26.COV2.S vaccination presenting as cerebral venous sinus thrombosis	4
The potential utilization of platelet-derived extracellular vesicles in clinical treatment	4
Nebulization with alkaline hipertonic ibuprofen induces a rapid increase in platelets circulating in COVID-19 patients but not in healthy subjects	4
Immunological platelet transfusion refractoriness: current insights from mechanisms to therapeutics	4
Alterations in platelet activity and endothelial glycocalyx biomarkers by treatment with an angiotensin converting enzyme inhibitor or an alpha-1 adrenoceptor antagonist in patients with hypertension:	4
Platelet-derived extracellular vesicles play an important role in platelet transfusion therapy	4
F11R/JAM-A: why do platelets express a molecule which is also present in tight junctions?	4
Efficacy and safety of high dose recombinant human thrombopoietin in the treatment of immune thrombocytopenia	4
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia	4
Scanning transmission X-ray microscopy study of subcellular granules in human platelets at the carbon K- and calcium L2,3-edges	4
GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction	4
Frequency and molecular basis of CD36 deficiency among platelet donors in Kunming, China	4
Successful treatment of acquired amegakaryocytic thrombocytopenia with eltrombopag and immunosuppressant	4
A case-control study of bleeding risk in children with 22q11.2 deletion syndrome undergoing cardiac surgery	4
Anti-GPIb/IX autoantibodies are associated with poor response to dexamethasone combined with rituximab therapy in primary immune thrombocytopenia patients	4
Murine models of glycoprotein Ib-IX	4
Platelet rich fibrin as a bioactive matrix with proosteogenic and proangiogenic properties on human healthy primary cells in vitro	4
C-type lectin-like receptor-2 (CLEC-2) is a key regulator of kappa-carrageenan-induced tail thrombosis model in mice	4
Neonatal platelet physiology and implications for transfusion	4
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	4
The CalDAG-GEFI/Rap1/αIIbβ3 axis minimally contributes to accelerated platelet clearance in mice with constitutive store-operated calcium entry	3
Determining the optimal storage time and temperature for performing platelet function assays and global hemostasis assays	3
Immune-induced thrombocytopenia by pembrolizumab: case report and review of literature	3
Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation	3
Thrombus remodelling by reversible and irreversible P2Y 12 inhibitors	3
Efficacy of platelet transfusion in cardiac surgery	3
Relationship between thrombocytopenia and prognosis in children with septic shock: a retrospective cohort study	3
Signaling mechanisms of the platelet glycoprotein Ib-IX complex	3
Potential biomarkers for inherited thrombocytopenia 2 identified by plasma proteomics	3
New presentations and exacerbations of immune thrombocytopenia after coronavirus disease 2019 vaccinations: the Taiwan experience	3
Bleeding and mortality risk in patients implanted with mechanical prosthetic heart valves with and without thrombocytopenia. Insights from the nationwide PLECTRUM registry	3
Storage of plasma-derived exosomes: evaluation of anticoagulant use and preserving temperatures	3

“Tailored” antiplatelet bridging therapy with cangrelor: moving toward personalized medicine	3
Effect of aspirin dosage on oxidative stress and platelet reactivity in patients undergoing coronary artery bypass grafting (APRICOT): randomized controlled trial	3
Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients	3
Glycan-Lectin interactions between platelets and tumor cells drive hematogenous metastasis	3
Eltrombopag modulates the phenotypic evolution and potential immunomodulatory roles of monocytes/macrophages in immune thrombocytopenia	3
Assessment of whole blood platelet aggregation in patients with cirrhosis: challenges and opportunities	3
Exploring the morphine-platelet activity association in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention	3
Fatal cerebral hemorrhage in a patient with thrombotic thrombocytopenic purpura with a normal platelet count during treatment with caplacizumab	3
Platelet activation by charged ligands and nanoparticles: platelet glycoprotein receptors as pattern recognition receptors	3
Recent advances on GPIb-IX-V complex	3
High fragmentation in platelet concentrates impacts the activation, procoagulant, and aggregatory capacity of platelets	3
Immature platelets and cardiovascular events in patients with stable coronary artery disease	3
The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model	3
The efficacy of platelet rich plasma on women with poor ovarian response: a systematic review and meta-analysis	3
Transcriptomic and functional characterization of megakaryocytic-derived platelet-like particles: impaired aggregation and prominent anti-tumor effects	3
Method article: anin vitroblood flow model to advance the study of platelet adhesion utilizing a damaged endothelium	3
Light transmission aggregometry for platelet function testing: position paper on current recommendations and French proposals for accreditation	3