Platelets

Article	Citations
Platelet Rich Plasma in Orthopedic Surgical Medicine.	57
Technical and biological review of authorized medical devices for platelets-rich plasma preparation in the field of regenerative medicine	45
PRP in wound healing applications	43
Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity	37
Platelet rich plasma in oral and maxillofacial surgery from the perspective of composition	37
The thrombopoietin receptor: revisiting the master regulator of platelet production	37
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib	35
Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases	33
Search for SARS-CoV-2 RNA in platelets from COVID-19 patients	30
Over time relationship between platelet reactivity, myocardial injury and mortality in patients with SARS-CoV-2-associated respiratory failure	28
Neonatal platelet physiology and implications for transfusion	27
Efficacy and safety evaluation of avatrombopag in immune thrombocytopenia: analyses of a phase III study and long-term extension	25
Rotational thromboelastometry (ROTEM) profiling of COVID–19 patients	25
Platelets and viruses	22
Release of α-granule contents during platelet activation	22
Application of Platelet Rich Fibrin in Tissue Engineering: Focus on Bone Regeneration	22
Extensive characterization of the composition and functional activities of five preparations of human platelet lysates for dedicated clinical uses	21
Human platelet lysates for human cell propagation	21
The structure of CLEC-2: mechanisms of dimerization and higher-order clustering	20
The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis	20
Bioinspired artificial platelets: past, present and future	18
Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count	18
Platelet–leukocyte interactions in the pathogenesis of viral infections	18
Immobilized collagen prevents shedding and induces sustained GPVI clustering and signaling in platelets	17
Diagnostic and prognostic role of platelets in patients with sepsis and septic shock	17

Cytosolic and mitochondrial Ca2+ signaling in procoagulant platelets	16
Platelets in dengue infection: more than a numbers game	16
Structure-function relationship of the platelet glycoprotein VI (GPVI) receptor: does it matter if it is a dimer or monomer?	16
The efficacy and safety of thrombopoietin receptor agonists in patients with chronic liver disease undergoing elective procedures: a systematic review and meta-analysis	15
Alterations in platelets during SARS-CoV-2 infection	15
Zinc: an endogenous and exogenous regulator of platelet function during hemostasis and thrombosis	15
Prevalence and natural history of variants in the ANKRD26 gene: a short review and update of reported cases	14
Platelet reticulated forms, size indexes and functional activity. Interactions in healthy volunteers.	14
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration	14
Severe thrombocytopenia in adults undergoing extracorporeal membrane oxygenation is predictive of thrombosis	14
Frozen and cold-stored platelets: reconsidered platelet products	14
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function	13
EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling	13
Sex differences in antiplatelet therapy: state-of-the art	13
Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B	13
Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets	13
Left ventricular assist device implantation causes platelet dysfunction and proinflammatory platelet-neutrophil interaction	13
Signaling mechanisms of the platelet glycoprotein Ib-IX complex	12
Differential effect of clopidogrel and ticagrelor on leukocyte count in relation to patient characteristics, biomarkers and genotype: a PLATO substudy	12
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia	12
Platelet Function Assays for the Diagnosis of Aspirin Resistance	12
Platelet activation by charged ligands and nanoparticles: platelet glycoprotein receptors as pattern recognition receptors	12
Efficacy and safety of eltrombopag in Chinese patients with chronic immune thrombocytopenia: stage 2 results from a multicenter phase III study	12
Platelet-derived microparticles stimulated by anti-β 2 GPI/β 2 GPI complexes induce pyroptosis of endothelial cells in antiphospho	12
Overcoming challenges in developing small molecule inhibitors for GPVI and CLEC-2	11
GPIb-IX-V and platelet clearance	11
Antiplatelet drugs and liver fibrosis	11
Platelet-derived mitochondria transfer facilitates wound-closure by modulating ROS levels in dermal fibroblasts	11
Thrombocytopenia and platelet count recovery in patients with sepsis-3: a retrospective observational study	10
Higher body mass index raises immature platelet count: potential contribution to obesity-related thrombosis	10
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming	10
P2X1: a unique platelet receptor with a key role in thromboinflammation	10
Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation	10
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans	10
Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and convalescent phase of COVID-19	10
Injectable platelet-rich fibrin positively regulates osteogenic differentiation of stem cells from implant hole via the ERK1/2 pathway	10
Distribution and quantification of activated platelets in platelet-rich fibrin matrices	10
The enigmatic nature of the triggering receptor expressed in myeloid cells -1 (TLT- 1)	10
A proprietary GMP human platelet lysate for the expansion of dermal fibroblasts for clinical applications	9
Evolution of platelet activation parameters during septic shock in intensive care unit	8
Why do platelets express K+ channels?	8
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of BMS-986141, a novel, reversible, small-molecule, PAR4 agonist in non-Japanese and Japanese healthy participants	8
Association between platelet counts and morbidity and mortality after endovascular repair for type B aortic dissection	8
Management of immune thrombotic thrombocytopenic purpura with caplacizumab: a Canadian, single-centre, real-world experience	8
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology	8
Platelet extracellular vesicles are efficient delivery vehicles of doxorubicin, an anti-cancer drug: preparation and in vitro characterization	8
The role of viscoelastic testing in assessing peri-interventional platelet function and coagulation	8
Ionotropic glutamate receptors in platelets: opposing effects and a unifying hypothesis	8
Complement activation negatively affects the platelet response to thrombopoietin receptor agonists in patients with immune thrombocytopenia: a prospective cohort study	7
Platelet-leukocyte aggregate formation and inflammation in patients with pulmonary arterial hypertension and CTEPH	7

Recovery of platelet reactivity following cessation of either aspirin or ticagrelor in patients treated with dual antiplatelet therapy following percutaneous coronary intervention: a GLOBAL LEADERS su	7
Platelets: bridging thrombosis and inflammation	7
Platelet activation and aggregation in different centrifugal-flow left ventricular assist devices	7
Relationship between Hepatitis B virus infection and platelet production and dysfunction	7
Whole blood platelet aggregation measurement by Multiplate™: potential diagnostic inaccuracy of correcting the results for the sample platelet count	7
The potency of selatogrel, a reversible antagonist of the P2Y12 receptor, is affected by calcium concentration	7
Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes	7
Pathogen inactivation of platelets for transfusion	7
Mean platelet volume: a prognostic marker in heart failure with preserved ejection fraction	7
Human Platelets and Influenza Virus: Internalization and Platelet Activation	7
Enrichment of plasma in platelets and extracellular vesicles by the counterflow to erythrocyte settling	7
Refractory immune thrombocytopenia successfully treated with bortezomib in a child with 22q11.2 deletion syndrome, complicated by Evans syndrome and hypogammaglobulinemia	7
Circulating microRNAs as biomarkers and mediators of platelet activation	7
New presentations and exacerbations of immune thrombocytopenia after coronavirus disease 2019 vaccinations: the Taiwan experience	7
Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study	7
Reply to “Peripheral versus central venous blood sampling does not influence the assessment of platelet activation in cirrhosis”	7
Helicobacter pylori protein that binds to and activates platelet specifically reacts with sera of H. pylori-associated chronic immune thrombocytopenia	7
Is the endogenous ligand for PEAR1 a proteoglycan: clues from the sea	7
Effect of leukocyte-platelet fibrin-rich wound reconstruction followed by full-thickness skin grafting in the treatment of diabetic foot Wagner grade 4 ulcer gangrene (toe area)	7
The efficacy of platelet rich plasma on anterior cruciate ligament reconstruction: a systematic review and meta-analysis	7
“Tailored” antiplatelet bridging therapy with cangrelor: moving toward personalized medicine	6
Immature platelets in COVID-19	6
Fatal cerebral hemorrhage in a patient with thrombotic thrombocytopenic purpura with a normal platelet count during treatment with caplacizumab	6
Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength	6
Flow cytometry identifies an early stage of platelet apoptosis produced by agonists of the P2X1 and P2X7 receptors	6
Cold stored platelets in the management of bleeding: is it about bioenergetics?	6
Innate immune TLR7 signaling mediates platelet activation and platelet-leukocyte aggregate formation in murine bacterial sepsis	6
Exacerbation of immune thrombocytopenia following initial and booster vaccination with Pfizer-BioNTech COVID-19 vaccine	6
Hemostasis-on-a-chip / incorporating the endothelium in microfluidic models of bleeding	6
Platelets after burn injury – hemostasis and beyond	6
Comparison of the effects of platelet concentrates produced by high and low-speed centrifugation protocols on the healing of critical-size defects in rat calvaria: a microtomographic and histomorphome	6
Intravenous abciximab as a rescue therapy for immediate reocclusion after successful mechanical thrombectomy in acute ischemic stroke patients	6
Platelet glycogenolysis is important for energy production and function	6
Eltrombopag modulates the phenotypic evolution and potential immunomodulatory roles of monocytes/macrophages in immune thrombocytopenia	6
Effect of avatrombopag in the management of severe and refractory chemotherapy-induced thrombocytopenia (CIT) in patients with solid tumors	6
Irradiation of platelets in transfusion medicine: risk and benefit judgments	6
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy	6
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro	5
Does hsa-miR-223-3p from platelet-derived extracellular vesicles regulate tissue factor expression in monocytic cells?	5
Mapping densely packed αIIbβ3 receptors in murine blood platelets with expansion microscopy	5
Method article: anin vitroblood flow model to advance the study of platelet adhesion utilizing a damaged endothelium	5
Peripheral versus central venous blood sampling does not influence the assessment of platelet activation in cirrhosis	5
Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study	5
Successful mRNA SARS-Cov-2 vaccine rechallenge after a first episode of immune thrombocytopenic purpura	5
Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients	5
Effects of leukocyte-rich platelet-rich plasma and leukocyte-poor platelet-rich plasma on the healing of bone-tendon interface of rotator cuff in a mice model	5
The effect of platelet-rich plasma injection on chronic Achilles tendinopathy and acute Achilles tendon rupture	5
Effects of platelet-rich fibrin produced by three centrifugation protocols on bone neoformation in defects created in rat calvaria	5
Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure	5
The utility of platelet activation biomarkers in thrombotic microangiopathies	5
Efficacy of platelet transfusion in cardiac surgery	5
A platelet lipidomics signature in patients with COVID-19	5
Current challenges in platelet transfusion	5
Profile of reticulated platelets in the early, subacute and late phases after transient ischemic attack or ischemic stroke	5
Effects of remote ischemic preconditioning on platelet activation and reactivity in patients undergoing cardiac surgery using cardiopulmonary bypass: a randomized controlled trial	5
Additional efficacy analysis of avatrombopag phase III data for the treatment of adults with immune thrombocytopenia	5
Healthy pediatric platelets are moderately hyporeactive in comparison with adults’ platelets	5
What can we learn from senescent platelets, their transcriptomes and proteomes?	5
Pre-operative platelet reactivity is a strong, independent predictor of bleeding complications after branched endovascular thoracoabdominal aortic aneurysm repair	4
A novel RUNX1 exon 3 - 7 deletion causing a familial platelet disorder	4
Immature platelets and cardiovascular events in patients with stable coronary artery disease	4
Platelet surface GPIbα, activated GPIIb-IIIa, and P-selectin levels in adult veno-arterial extracorporeal membrane oxygenation patients	4
Platelet parameters and risk of hypertension disorders of pregnancy: a propensity score adjusted analysis	4
The effect of short-term cryopreservation on the properties and functionality of platelet-rich plasma	4
Platelet response to aspirin in UK and Irish pregnancy cohorts: a genome-wide approach	4
European Delphi panel to build consensus on tapering and discontinuing thrombopoietin receptor agonists in immune thrombocytopenia	4
Mind the gap: connexins and pannexins in platelet function	4
ADP-induced platelet reactivity and bleeding events in patients with acute myocardial infarction complicated by cardiogenic shock	4
Effects of platelets activated by different agonists on fibrin formation and thrombin generation	4
Effects of electret coating technology on coronary stent thrombogenicity	4
The Total Thrombus Formation (T-TAS) platelet (PL) assay, a novel test that evaluates whole blood platelet thrombus formation under physiological conditions	4
Mass cytometry of platelet-rich plasma: a new approach to analyze platelet surface expression and reactivity	4
Rapid isolation of mature murine primary megakaryocytes by size exclusion via filtration	4
Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP	4
Feasibility of a mean platelet volume standard: an international council for standardization in hematology (ICSH) inter-laboratory study	4
Aquaporins in platelet function	4
Successful treatment of acquired amegakaryocytic thrombocytopenia with eltrombopag and immunosuppressant	4
Efficacy and safety of abciximab versus tirofiban in addition to ticagrelor in STEMI patients undergoing primary percutaneous intervention	4
Effect of iron supplementation on platelet count in adult patients with iron deficiency anemia	4
Contributing role of mitochondrial energy metabolism on platelet adhesion, activation and thrombus formation under blood flow conditions	4

High fragmentation in platelet concentrates impacts the activation, procoagulant, and aggregatory capacity of platelets	4
Potential biomarkers for inherited thrombocytopenia 2 identified by plasma proteomics	4
Romiplostim for PARP inhibitor-induced thrombocytopenia in solid tumor malignancies	4
Combining human platelet proteomes and transcriptomes: possibilities and challenges	4
Significance of mild thrombocytopenia in maintenance hemodialysis patients; a retrospective cohort study	3
Thrombocytopathy vs Platelet hyper-reactivity in COVID-19: diverse pathologies, disease outcomes and therapeutic implications	3
What can we learn from the platelet lipidome?	3
Analysis of clinical characteristics and treatment efficacy in two pediatric cases of ANKRD26 -related thrombocytopenia	3
Post-cardiac surgery thrombotic thrombocytopenic purpura: presence of anti-ADAMTS13 autoantibodies at preoperative baseline	3
Thrombus remodelling by reversible and irreversible P2Y 12 inhibitors	3
Clopidogrel versus ticagrelor in East Asian patients aged 75 years or older with acute coronary syndrome: observations from the GF-APT registry	3
The state of the art and future of PRP therapy	3
TSST-1 protein exerts indirect effect on platelet activation and apoptosis	3
Pathogenic mechanisms contributing to thrombocytopenia in patients with systemic lupus erythematosus	3
Endothelial transmigration of platelets depends on soluble factors released by activated endothelial cells and monocytes	3
Evaluating stored platelet shape change using imaging flow cytometry	3
α-Synuclein is the major platelet isoform but is dispensable for activation, secretion, and thrombosis	3
Platelet-derived extracellular vesicles play an important role in platelet transfusion therapy	3
Clinical features and treatment effect of HIV-associated immune thrombocytopenia—single center Ten-Years data summary	3
GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction	3
Glycan-Lectin interactions between platelets and tumor cells drive hematogenous metastasis	3
New αIIbβ3 variants in 28 Turkish Glanzmann patients; structural hypothesis for complex activation by residues variations in I-EGF domains	3
Correlation of CLEC1B haplotypes with plasma levels of soluble CLEC-2 in healthy individuals	3
Laser-triggered intelligent drug delivery and anti-cancer photodynamic therapy using platelets as the vehicle	3
Not-high before-treatment platelet reactivity in patients with STEMI: prevalence, clinical characteristics, response to therapy and outcomes	3
EDI(torial): equality, diversity, and inclusion and platelets - 2021	3
F11R/JAM-A: why do platelets express a molecule which is also present in tight junctions?	3
Building platelet phenotypes: Diaphanous-related formin 1 (DIAPH1)-related disorder	3
An optimized agonist peptide of protease-activated receptor 4 and its use in a validated platelet-aggregation assay	3
Prospective assessment of platelet function in patients undergoing elective resection of glioblastoma multiforme	3
Increased circulating platelet-derived extracellular vesicles in severe COVID-19 disease	3
How can we use proteomics to learn more about platelets?	3
A novel frameshiftGP1BBmutation causes autosomal dominant macrothrombocytopenia with decreased vWF receptor expression but normal platelet aggregation	3
The utility of flow cytometric platelet forward scatter as an alternative to mean platelet volume	3
Hiding in plain sight – platelets, the silent carriers of HIV-1	3
Actin polymerization regulates glycoprotein Ibα shedding	3
Positive correlations between plasma BPI level and MPO-DNA and S100A8/A9 in myocardial infarction	3
Severe thrombocytopenia and intracranial hemorrhage in a newborn with Noonan syndrome and neonatal alloimmune thrombocytopenia	3