OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	471
Oncogenic viruses, cancer biology, and innate immunity	121
The future of vaccination in Latin America: learning from the COVID-19 pandemic	115
An easy pill to swallow: oral recombinant vaccines for the 21st century	93
Can we cure primary biliary cholangitis?	88
Can juvenile idiopathic arthritis be cured?	66
TAP-ing into the cross-presentation secrets of dendritic cells	65
Mechanistic insights into epigenetic contributions to psoriasis pathogenesis and their clinical implications	62
T cells in Sjögren’s disease: update on their role in salivary gland pathogenesis and treatment	60
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	60
Principles and practical applications of structure-based vaccine design	59
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	57
Neuropsychiatric lupus: a myriad of symptoms requires a myriad of models	56
Nutritional modulation of antitumor immunity	56
The epidermal immune microenvironment plays a central role in the pathogenesis of psoriasis	51
Pharmacotherapeutic strategies to promote regulatory T cell function in autoimmunity	46
Commander-in-chief: monocytes rally the troops for defense against aspergillosis	43
B cell–targeted therapies in autoimmune skin disease: current advances and challenges	37
Can we cure Behçet syndrome?	36
Innate antiviral immunity and immunometabolism in hepatocytes	34
Complement in antiphospholipid syndrome, time to target?	34
Necroptosis in immunity, tissue homeostasis, and cancer	34
A critical look at observational studies	33
Reconsidering the immunological aspects of solid-phase assays for antiphospholipid antibodies detection	33
Can sarcoidosis be cured?	32

Mapping the synovial immune ecosystem in rheumatoid arthritis: cellular cartography and pathotype-guided immune restoration	32
Some thoughts about what non-mammalian jawed vertebrates are telling us about antigen processing and peptide loading of MHC molecules	32
Regulation of MHC class II and CD86 expression by March-I in immunity and disease	31
Metabolism and macrophages in the tumor microenvironment	30
Noncanonical ion channel signaling in neurovascular barrier regulation and immune cell trafficking	29
Mapping and modelling human B cell maturation in the germinal centre	29
Can we cure bullous skin diseases?	28
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?	28
Patterns of bacterial viability governing noncanonical inflammasome activation	28
The power of genetics in decoding Sjögren’s disease: current status and future development	28
Editorial Board	28
Mechanistic considerations linking SARS-CoV-2 infection, inflammation, and the loss of immune tolerance	27
Animal models of autoimmune encephalitis	26
Implication of epigenetic factors in development and recurrence of psoriasis	26
Bioinspired vaccines to enhance MHC class-I antigen cross-presentation	25
Editorial Board	24
Nucleic acid triggers of autoimmunity and autoinflammation	23
Harnessing IgG Fc glycosylation for clinical benefit	23
Use of synthetic data, a novel paradigm for immunopathology	23
Game of Omes: ribosome profiling expands the MHC-I immunopeptidome	23
Thetis cells: regulators of intestinal immune tolerance	22
Outer membrane vesicle-based intranasal vaccines	22
Can we cure antiphospholipid syndrome?	22
Resolving adjuvant mode of action to enhance vaccine efficacy	22
HLA-B27 as a potential target for the cure of axial spondyloarthritis	21
Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans	21
Killing in self-defense: proapoptotic drugs to eliminate intracellular pathogens	21
Immune responses to Toxoplasma gondii	21
Epigenetics: the link between environmental exposures and autoimmune diseases	21
The increasing prevalence of autoimmunity and autoimmune diseases: an urgent call to action for improved understanding, diagnosis, treatment, and prevention	21
Rheumatoid arthritis — the role of T cells in this complex systemic autoimmune disease	20
New insights into the mechanisms regulating plasma cell survival and longevity	20
Treating sarcoidosis: when less is more	20
Editorial Board	20
Won’t you be my neighbor? Control of the immune response by stromal and immune cell microenvironments within the lymph node	20
A throwback on 25 years in pannexin research	19
Intracellular complement in monocytes and macrophages: emerging roles	19
Neuroimmune crosstalk in the skin: a delicate balance governing inflammatory processes	19
B cell memory of Immunoglobulin E (IgE) antibody responses in allergy	19
Targeting synovial fibroblast KCa1.1 channels in rheumatoid arthritis	18
Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity	18
Mechanisms and risk factors for perinatal allergic disease	18
Clinical trials and new therapies in Sjögren’s disease	18
Can we cure lupus?	18
New autoantibodies in Sjögren's disease	18
‘Can we cure IgG4-related diseases?’	17
Immune dyshomeostasis in lifestyle-associated diseases: a new paradigm for personalized medicine and prevention	17
Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa	17
Metabolomic signaling in sarcoidosis pathogenesis	17
Multiple sclerosis: a disease or a syndrome?	17

Drivers and shapers of macrophages specification in the developing brain	16
A critical look at animal and cellular models in autoinflammatory diseases	16
Immunometabolic regulation of germinal centers and its implications for aging	16
Tumor immune evasion through loss of MHC class-I antigen presentation	16
Regulation of type I and type III interferon induction in response to pathogen sensing	16
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment	16
Why we need to maintain a critical view on big data and artificial intelligence predictions	15
Eliciting or silencing complement activation: strategies for optimizing monoclonal antibodies functions	15
Advances and challenges in investigating B-cells via single-cell transcriptomics	15
Challenges in diagnosis of sarcoidosis	15
Red blood cell alloimmunization immunogenetic risk factor	15
The role of epigenetics in inflammatory memory	15
New insights and approaches for analyses of immunopeptidomes	14
The role of epigenetic modifications in systemic autoinflammatory diseases	14
Autoimmunity, epitope analysis, and molecular mimicry	14
Composite and pragmatic measures in psoriatic arthritis: bridging trials and clinical feasibility	14
Ocular sarcoidosis: from clinical signs to targeted interventions	14
IFNε, IFNω and IFNλ: interferons defending the mucosa	13
TH17 cell immune adaptation	13
Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	13
Defining the niche for stem-like CD8+ T cell formation and function	13
HyperIgE in hypomorphic recombination-activating gene defects	12
Differential signaling by type-I and type-III interferons in mucosa	12
Addressing unmet needs in rheumatoid arthritis: the challenge of translating multi-omics into precision therapies	12
The thymoproteasome in shaping the CD8+ T-cell repertoire	12
Functional flexibility and plasticity in immune control of systemic Salmonella infection	12
Curing inflammatory bowel diseases: breaking the barriers of current therapies– emerging strategies for a definitive treatment	12
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	12
Layers of defense: protection from respiratory viruses by epithelial-intrinsic immunity	12
Inherited human ZNF341 deficiency	12
The choroid plexus in inflammatory and degenerative diseases of the central nervous system	12
Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease	11
From metabolomics to transfusion-associated immunomodulation	11
Molecular insights into metabolite antigen recognition by mucosal-associated invariant T cells	11
Inflammation induced by lipid mediators and protein from transfusion products	11
Human inborn errors of type I interferon–independent intrinsic immunity in nonleukocytic cells	11
Editorial Board	11
A liver–mitochondria–immune axis in Parkinson’s disease: emerging perspectives on a hepatic origin for mitochondrial autoimmunity as a driver of Parkinson’s disease	11
Harnessing dendritic cell diversity in cancer immunotherapy	11
Local complement inhibition by selective precision-targeted therapies	11
T follicular helper cells in food allergy	11