OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
The future of vaccination in Latin America: learning from the COVID-19 pandemic	269
Revisiting the role of MRGPRX2 on hypersensitivity reactions to neuromuscular blocking drugs	193
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	150
An easy pill to swallow: oral recombinant vaccines for the 21st century	84
Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy	84
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	75
Oncogenic viruses, cancer biology, and innate immunity	72
TAP-ing into the cross-presentation secrets of dendritic cells	67
Mycobacterial diseases in patients with inborn errors of immunity	65
COVID-19 vaccines	63
A critical review of measures of childhood vaccine confidence	62
Principles and practical applications of structure-based vaccine design	60
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	58
Ebola virus disease: current vaccine solutions	58
Necroptosis in immunity, tissue homeostasis, and cancer	57
Increasing hepatitis B vaccination coverage of healthcare workers — global lessons for South Africa	57
Beyond the gastric epithelium — the paradox of Helicobacter pylori-induced immune responses	57
Some thoughts about what non-mammalian jawed vertebrates are telling us about antigen processing and peptide loading of MHC molecules	56
Host genetics of innate immune system in infection	51
Innate antiviral immunity and immunometabolism in hepatocytes	50
Commander-in-chief: monocytes rally the troops for defense against aspergillosis	46
Safety switches for adoptive cell therapy	46
Immunological lessons from genome-wide association studies of infections	45
Nutritional modulation of antitumor immunity	44
Regulation of MHC class II and CD86 expression by March-I in immunity and disease	44

Metabolism and macrophages in the tumor microenvironment	43
Bioinspired vaccines to enhance MHC class-I antigen cross-presentation	42
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?	40
Human MALT1 deficiency and predisposition to infections	39
T follicular helper cells and their impact on humoral responses during pathogen and vaccine challenge	38
Conformational sensing of major histocompatibility complex (MHC) class I molecules by immune receptors and intracellular assembly factors	38
Mapping and modelling human B cell maturation in the germinal centre	38
Signals governing monocyte differentiation during inflammation	37
Patterns of bacterial viability governing noncanonical inflammasome activation	36
Antibody glycosylation directs innate and adaptive immune collaboration	36
Monogenic autoimmunity and infectious diseases: the double-edged sword of immune dysregulation	36
Editorial overview: Recent advances in research of IgE-mediated and IgE-independent allergies, an overview	35
Editorial Board	35
Bidirectional sensory neuron–immune interactions: a new vision in the understanding of allergic inflammation	35
Application of T cell receptor (TCR) repertoire analysis for the advancement of cancer immunotherapy	34
Game of Omes: ribosome profiling expands the MHC-I immunopeptidome	34
Nucleic acid triggers of autoimmunity and autoinflammation	34
Resolving adjuvant mode of action to enhance vaccine efficacy	34
Harnessing IgG Fc glycosylation for clinical benefit	34
The increasing prevalence of autoimmunity and autoimmune diseases: an urgent call to action for improved understanding, diagnosis, treatment, and prevention	33
The politics of Covid-19 vaccine confidence	32
Outer membrane vesicle-based intranasal vaccines	29
Editorial Board	29
Immune responses to Toxoplasma gondii	29
New insights into the mechanisms regulating plasma cell survival and longevity	28
Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans	27
Killing in self-defense: proapoptotic drugs to eliminate intracellular pathogens	27
Neuroimmune crosstalk in the skin: a delicate balance governing inflammatory processes	25
Inborn errors of autophagy and infectious diseases	25
B cell memory of Immunoglobulin E (IgE) antibody responses in allergy	25
cGAS-like receptor-mediated immunity: the insect perspective	24
Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity	24
Regulation of type I and type III interferon induction in response to pathogen sensing	23
The role of CD4 T cells in rejection of solid tumors	23
Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa	22
Mechanisms and risk factors for perinatal allergic disease	22
Tryptophan metabolism in brain tumors — IDO and beyond	22
Innate control of adaptive immunity and adaptive instruction of innate immunity: bi-directional flow of information	22
Publisher's Note	21
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment	21
ICOSL in host defense at epithelial barriers: lessons from ICOSLG deficiency	21
Advances and challenges in investigating B-cells via single-cell transcriptomics	21
IFNε, IFNω and IFNλ: interferons defending the mucosa	21
Tumor immune evasion through loss of MHC class-I antigen presentation	21
Immunometabolic regulation of germinal centers and its implications for aging	21
TH17 cell immune adaptation	21
Intrinsic and extrinsic regulation of IgE B cell responses	20
New insights and approaches for analyses of immunopeptidomes	20
Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	20
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	19

Editorial overview: BAFF family ligands and receptors – a license to live	19
Defining the niche for stem-like CD8+ T cell formation and function	19
Monogenic susceptibility to live viral vaccines	18
HyperIgE in hypomorphic recombination-activating gene defects	18
Functional flexibility and plasticity in immune control of systemic Salmonella infection	18
Infections in the monogenic autoimmune syndrome APECED	18
The thymoproteasome in shaping the CD8+ T-cell repertoire	18
Editorial overview: Communities in immune cell signaling	17
Differential signaling by type-I and type-III interferons in mucosa	17
Editorial overview: Tumour immunology: Engineered T cell therapy of cancer: current success and future improvements	16
Membrane cofactor protein (MCP; CD46): deficiency states and pathogen connections	16
Inherited human ZNF341 deficiency	16
Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease	16
Mast cell tryptases in allergic inflammation and immediate hypersensitivity	16
Immunity to EBV as revealed by immunedeficiencies	16
Innate immune sensing by epithelial barriers	15
Microbiota and B-1 B cell repertoire development in mice	15
T follicular helper cells in food allergy	15
Human inborn errors of immunity to oncogenic viruses	15
Editorial Board	15
Harnessing dendritic cell diversity in cancer immunotherapy	15
Inflammasomes and their role in PANoptosomes	15
Editorial Board	15