OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Mechanistic insights into epigenetic contributions to psoriasis pathogenesis and their clinical implications	302
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	99
TAP-ing into the cross-presentation secrets of dendritic cells	95
An easy pill to swallow: oral recombinant vaccines for the 21st century	87
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	78
The future of vaccination in Latin America: learning from the COVID-19 pandemic	74
Can juvenile idiopathic arthritis be cured?	70
Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy	68
Principles and practical applications of structure-based vaccine design	62
Oncogenic viruses, cancer biology, and innate immunity	58
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	53
Pharmacotherapeutic strategies to promote regulatory T cell function in autoimmunity	51
Can sarcoidosis be cured?	49
Neuropsychiatric lupus: a myriad of symptoms requires a myriad of models	49
Complement in antiphospholipid syndrome, time to target?	49
Can we cure Behçet syndrome?	48
Nutritional modulation of antitumor immunity	45
Some thoughts about what non-mammalian jawed vertebrates are telling us about antigen processing and peptide loading of MHC molecules	44
Beyond the gastric epithelium — the paradox of Helicobacter pylori-induced immune responses	43
Necroptosis in immunity, tissue homeostasis, and cancer	42
Regulation of MHC class II and CD86 expression by March-I in immunity and disease	40
Innate antiviral immunity and immunometabolism in hepatocytes	34
Host genetics of innate immune system in infection	33
Commander-in-chief: monocytes rally the troops for defense against aspergillosis	30
Metabolism and macrophages in the tumor microenvironment	30

B cell–targeted therapies in autoimmune skin disease: current advances and challenges	29
Mapping and modelling human B cell maturation in the germinal centre	28
Safety switches for adoptive cell therapy	28
Implication of epigenetic factors in development and recurrence of psoriasis	28
Antibody glycosylation directs innate and adaptive immune collaboration	27
Mechanistic considerations linking SARS-CoV-2 infection, inflammation, and the loss of immune tolerance	27
T follicular helper cells and their impact on humoral responses during pathogen and vaccine challenge	27
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?	25
Signals governing monocyte differentiation during inflammation	24
Patterns of bacterial viability governing noncanonical inflammasome activation	24
Animal models of autoimmune encephalitis	24
Bioinspired vaccines to enhance MHC class-I antigen cross-presentation	24
Harnessing IgG Fc glycosylation for clinical benefit	23
Can we cure antiphospholipid syndrome?	23
Editorial Board	23
Can we cure bullous skin diseases?	23
Nucleic acid triggers of autoimmunity and autoinflammation	22
Application of T cell receptor (TCR) repertoire analysis for the advancement of cancer immunotherapy	22
Resolving adjuvant mode of action to enhance vaccine efficacy	21
Game of Omes: ribosome profiling expands the MHC-I immunopeptidome	21
Thetis cells: regulators of intestinal immune tolerance	20
Outer membrane vesicle-based intranasal vaccines	20
Immune responses to Toxoplasma gondii	20
The increasing prevalence of autoimmunity and autoimmune diseases: an urgent call to action for improved understanding, diagnosis, treatment, and prevention	19
Killing in self-defense: proapoptotic drugs to eliminate intracellular pathogens	18
B cell memory of Immunoglobulin E (IgE) antibody responses in allergy	18
New insights into the mechanisms regulating plasma cell survival and longevity	18
Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans	18
HLA-B27 as a potential target for the cure of axial spondyloarthritis	18
cGAS-like receptor-mediated immunity: the insect perspective	17
Neuroimmune crosstalk in the skin: a delicate balance governing inflammatory processes	17
Editorial Board	17
Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity	17
Epigenetics: the link between environmental exposures and autoimmune diseases	17
Intracellular complement in monocytes and macrophages: emerging roles	17
Mechanisms and risk factors for perinatal allergic disease	16
Rheumatoid arthritis — the role of T cells in this complex systemic autoimmune disease	16
Can we cure lupus?	15
Tumor immune evasion through loss of MHC class-I antigen presentation	15
Drivers and shapers of macrophages specification in the developing brain	15
The role of CD4 T cells in rejection of solid tumors	15
Regulation of type I and type III interferon induction in response to pathogen sensing	15
Innate control of adaptive immunity and adaptive instruction of innate immunity: bi-directional flow of information	15
‘Can we cure IgG4-related diseases?’	15
TH17 cell immune adaptation	14
IFNε, IFNω and IFNλ: interferons defending the mucosa	14
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment	14
Advances and challenges in investigating B-cells via single-cell transcriptomics	14
Immunometabolic regulation of germinal centers and its implications for aging	14
Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa	14

The role of epigenetic modifications in systemic autoinflammatory diseases	14
Eliciting or silencing complement activation: strategies for optimizing monoclonal antibodies functions	14
Differential signaling by type-I and type-III interferons in mucosa	13
Editorial overview: Communities in immune cell signaling	13
The role of epigenetics in inflammatory memory	13
Publisher's Note	13
The choroid plexus in inflammatory and degenerative diseases of the central nervous system	13
Functional flexibility and plasticity in immune control of systemic Salmonella infection	13
Red blood cell alloimmunization immunogenetic risk factor	13
New insights and approaches for analyses of immunopeptidomes	13
Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	13
The thymoproteasome in shaping the CD8+ T-cell repertoire	13
HyperIgE in hypomorphic recombination-activating gene defects	13
Defining the niche for stem-like CD8+ T cell formation and function	13
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	13
Editorial overview: Tumour immunology: Engineered T cell therapy of cancer: current success and future improvements	12
Microbiota and B-1 B cell repertoire development in mice	12
The role of intestinal bacteria in promoting tolerance to food	12
Inflammasomes and their role in PANoptosomes	12
Curing inflammatory bowel diseases: breaking the barriers of current therapies– emerging strategies for a definitive treatment	12
From metabolomics to transfusion-associated immunomodulation	12
Editorial Board	12
Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease	12
Inherited human ZNF341 deficiency	12
T follicular helper cells in food allergy	12
Molecular insights into metabolite antigen recognition by mucosal-associated invariant T cells	12
Harnessing microglia-based cell therapies for the treatment of neurodegenerative diseases	12
Inflammation induced by lipid mediators and protein from transfusion products	12