OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	331
Can juvenile idiopathic arthritis be cured?	99
The future of vaccination in Latin America: learning from the COVID-19 pandemic	99
Mechanistic insights into epigenetic contributions to psoriasis pathogenesis and their clinical implications	89
An easy pill to swallow: oral recombinant vaccines for the 21st century	81
TAP-ing into the cross-presentation secrets of dendritic cells	77
Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy	70
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	69
Principles and practical applications of structure-based vaccine design	62
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	60
Oncogenic viruses, cancer biology, and innate immunity	53
Beyond the gastric epithelium — the paradox of Helicobacter pylori-induced immune responses	52
The epidermal immune microenvironment plays a central role in the pathogenesis of psoriasis	51
Can we cure Behçet syndrome?	51
Can sarcoidosis be cured?	50
Neuropsychiatric lupus: a myriad of symptoms requires a myriad of models	50
Innate antiviral immunity and immunometabolism in hepatocytes	47
Complement in antiphospholipid syndrome, time to target?	45
Commander-in-chief: monocytes rally the troops for defense against aspergillosis	44
Host genetics of innate immune system in infection	42
B cell–targeted therapies in autoimmune skin disease: current advances and challenges	41
Some thoughts about what non-mammalian jawed vertebrates are telling us about antigen processing and peptide loading of MHC molecules	37
Necroptosis in immunity, tissue homeostasis, and cancer	35
Nutritional modulation of antitumor immunity	31
Safety switches for adoptive cell therapy	31

Pharmacotherapeutic strategies to promote regulatory T cell function in autoimmunity	30
Metabolism and macrophages in the tumor microenvironment	30
Regulation of MHC class II and CD86 expression by March-I in immunity and disease	30
Mapping and modelling human B cell maturation in the germinal centre	29
Mechanistic considerations linking SARS-CoV-2 infection, inflammation, and the loss of immune tolerance	29
Patterns of bacterial viability governing noncanonical inflammasome activation	28
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?	28
Editorial Board	26
Can we cure bullous skin diseases?	26
Antibody glycosylation directs innate and adaptive immune collaboration	25
T follicular helper cells and their impact on humoral responses during pathogen and vaccine challenge	25
Animal models of autoimmune encephalitis	24
Implication of epigenetic factors in development and recurrence of psoriasis	24
Game of Omes: ribosome profiling expands the MHC-I immunopeptidome	23
Resolving adjuvant mode of action to enhance vaccine efficacy	23
Signals governing monocyte differentiation during inflammation	23
Nucleic acid triggers of autoimmunity and autoinflammation	23
Bioinspired vaccines to enhance MHC class-I antigen cross-presentation	23
Can we cure antiphospholipid syndrome?	22
Editorial Board	22
Harnessing IgG Fc glycosylation for clinical benefit	22
Outer membrane vesicle-based intranasal vaccines	21
Thetis cells: regulators of intestinal immune tolerance	21
Immune responses to Toxoplasma gondii	21
Killing in self-defense: proapoptotic drugs to eliminate intracellular pathogens	20
Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans	20
The increasing prevalence of autoimmunity and autoimmune diseases: an urgent call to action for improved understanding, diagnosis, treatment, and prevention	20
Application of T cell receptor (TCR) repertoire analysis for the advancement of cancer immunotherapy	20
Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity	19
Neuroimmune crosstalk in the skin: a delicate balance governing inflammatory processes	18
Intracellular complement in monocytes and macrophages: emerging roles	18
B cell memory of Immunoglobulin E (IgE) antibody responses in allergy	17
Epigenetics: the link between environmental exposures and autoimmune diseases	17
cGAS-like receptor-mediated immunity: the insect perspective	17
New insights into the mechanisms regulating plasma cell survival and longevity	17
HLA-B27 as a potential target for the cure of axial spondyloarthritis	17
Editorial Board	17
Treating sarcoidosis: when less is more	17
Rheumatoid arthritis — the role of T cells in this complex systemic autoimmune disease	17
Can we cure lupus?	16
Regulation of type I and type III interferon induction in response to pathogen sensing	16
Drivers and shapers of macrophages specification in the developing brain	16
Innate control of adaptive immunity and adaptive instruction of innate immunity: bi-directional flow of information	16
‘Can we cure IgG4-related diseases?’	16
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment	16
Mechanisms and risk factors for perinatal allergic disease	15
The role of epigenetic modifications in systemic autoinflammatory diseases	15
The role of CD4 T cells in rejection of solid tumors	15
Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa	15
Tumor immune evasion through loss of MHC class-I antigen presentation	15

Immunometabolic regulation of germinal centers and its implications for aging	15
Red blood cell alloimmunization immunogenetic risk factor	14
Defining the niche for stem-like CD8+ T cell formation and function	14
IFNε, IFNω and IFNλ: interferons defending the mucosa	14
Advances and challenges in investigating B-cells via single-cell transcriptomics	14
Autoimmunity, epitope analysis, and molecular mimicry	14
New insights and approaches for analyses of immunopeptidomes	14
Eliciting or silencing complement activation: strategies for optimizing monoclonal antibodies functions	14
Publisher's Note	14
Challenges in diagnosis of sarcoidosis	14
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	13
Editorial overview: Communities in immune cell signaling	13
Curing inflammatory bowel diseases: breaking the barriers of current therapies– emerging strategies for a definitive treatment	13
TH17 cell immune adaptation	13
The thymoproteasome in shaping the CD8+ T-cell repertoire	13
HyperIgE in hypomorphic recombination-activating gene defects	13
Functional flexibility and plasticity in immune control of systemic Salmonella infection	13
The role of epigenetics in inflammatory memory	13
Differential signaling by type-I and type-III interferons in mucosa	13
Layers of defense: protection from respiratory viruses by epithelial-intrinsic immunity	13
Editorial overview: Tumour immunology: Engineered T cell therapy of cancer: current success and future improvements	13
Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	13
The choroid plexus in inflammatory and degenerative diseases of the central nervous system	13
T follicular helper cells in food allergy	13
Inherited human ZNF341 deficiency	13
From metabolomics to transfusion-associated immunomodulation	12
Editorial Board	12
Microbiota and B-1 B cell repertoire development in mice	12
Microevolution of Pseudomonas aeruginosa in the airways of people with cystic fibrosis	12
Harnessing dendritic cell diversity in cancer immunotherapy	12
Human inborn errors of type I interferon–independent intrinsic immunity in nonleukocytic cells	12
Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease	12
Inflammation induced by lipid mediators and protein from transfusion products	12