OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
COVID-19 vaccines	223
Type I interferon in the pathogenesis of systemic lupus erythematosus	137
Tryptophan and indole metabolism in immune regulation	110
The NLRP3 inflammasome triggers sterile neuroinflammation and Alzheimer’s disease	107
The increasing prevalence of autoimmunity and autoimmune diseases: an urgent call to action for improved understanding, diagnosis, treatment, and prevention	94
Vaccine hesitancy in migrant communities: a rapid review of latest evidence	75
The role of CD4 T cells in rejection of solid tumors	65
Ebola virus disease: current vaccine solutions	61
Type I interferons and SARS-CoV-2: from cells to organisms	60
CBASS phage defense and evolution of antiviral nucleotide signaling	55
The politics of Covid-19 vaccine confidence	53
Anti-interferon-γ autoantibody-associated immunodeficiency	53
Natural killers or ILC1s? That is the question	52
A critical review of measures of childhood vaccine confidence	52
Cytokines and transcription factors in the differentiation of CD4+ T helper cell subsets and induction of tissue inflammation and autoimmunity	50
The multifaceted functions of follicular regulatory T cells	49
Viral vector vaccines	49
Detrimental activation of AhR pathway in cancer: an overview of therapeutic strategies	49
Exploring cardiac macrophage heterogeneity in the healthy and diseased myocardium	48
Sensing and clearance of apoptotic cells	47
Gut microbiome-mediated regulation of neuroinflammation	46
HLA variation and antigen presentation in COVID-19 and SARS-CoV-2 infection	46
Trained immunity: implications for vaccination	45
Innate lymphoid cells: from helper to killer	45
The innate immune system and cell death in autoinflammatory and autoimmune disease	45

Membrane cofactor protein (MCP; CD46): deficiency states and pathogen connections	44
Tuning tuft cells: new ligands and effector functions reveal tissue-specific function	44
Regulation of host physiology and immunity by microbial indole-3-aldehyde	44
The high affinity IgE receptor: a signaling update	41
Inhibitory receptor agonists: the future of autoimmune disease therapeutics?	40
Diversity and function of brain-associated macrophages	38
New insights into B cells as antigen presenting cells	38
Regulation of innate immunity by Nrf2	35
Signals governing monocyte differentiation during inflammation	34
New Treg cell-based therapies of autoimmune diseases: towards antigen-specific immune suppression	34
Interventions for vaccine hesitancy	33
Major histocompatibility complex (MHC) class I and class II proteins: impact of polymorphism on antigen presentation	33
Charcot–Leyden crystals and other protein crystals driving type 2 immunity and allergy	33
Inborn errors of STAT1 immunity	33
Mechanisms for control of skin immune function by the microbiome	33
MHC I assembly and peptide editing — chaperones, clients, and molecular plasticity in immunity	32
Mast cell tryptases in allergic inflammation and immediate hypersensitivity	32
Intrinsic and extrinsic regulation of IgE B cell responses	31
The role of enteric glia in intestinal immunity	31
There is no gene for CVID — novel monogenetic causes for primary antibody deficiency	31
Inflammasome activation and evasion by bacterial pathogens	29
Immune checkpoint receptors in autoimmunity	29
Supply and delivery of vaccines for global health	29
TACI deficiency — a complex system out of balance	29
Innate immune defenses at the maternal-fetal interface	28
Tryptophan metabolism in brain tumors — IDO and beyond	28
Inborn errors of IL-6 family cytokine responses	28
Adverse events induced by immune checkpoint inhibitors	27
T cell immunity to cytomegalovirus infection	27
Emerging roles of circular RNAs in innate immunity	27
Mycobacterial diseases in patients with inborn errors of immunity	27
Role of the NF-κB system in context-specific tuning of the inflammatory gene response	26
Therapeutic induction of tolerogenic dendritic cells via aryl hydrocarbon receptor signaling	26
Resolving adjuvant mode of action to enhance vaccine efficacy	25
Principles and practical applications of structure-based vaccine design	25
Inflammation, immunity, and antigen persistence in post-acute sequelae of SARS-CoV-2 infection	24
Modulation of the tumor micro-environment by CD8+ T cell-derived cytokines	24
Immune responses to Toxoplasma gondii	24
Immunity to EBV as revealed by immunedeficiencies	23
BAFF signaling in health and disease	23
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	22
Down syndrome and type I interferon: not so simple	22
Reflection: burden of cervical cancer in Sub-Saharan Africa and progress with HPV vaccination	22
Atypical B cells in chronic infectious diseases and systemic autoimmunity: puzzles with many missing pieces	21
New insights into human immunity from ancient genomics	19
Resistance mechanisms to checkpoint inhibitors	19
Safety switches for adoptive cell therapy	19
The double life of serotonin metabolites: in the mood for joining neuronal and immune systems	19
Autoimmunity, IgE and FcεRI-bearing cells	19
Innate immune sensing by epithelial barriers	18

Mechanisms of response and resistance to CAR T cell therapies	18
Infections in the monogenic autoimmune syndrome APECED	18
Adoptive T cell therapy of solid tumors: time to team up with immunogenic chemo/radiotherapy	18
The burgeoning role of MR1-restricted T-cells in infection, cancer and autoimmune disease	18
Manipulating antigen presentation for antigen-specific immunotherapy of autoimmune diseases	18
Epigenetic adjuvants: durable reprogramming of the innate immune system with adjuvants	18
Keeping up with the stress of antibody production: BAFF and APRIL maintain memory plasma cells	18
Cross-reactivity between microbial and tumor antigens	18
A unifying hypothesis on the central role of reactive oxygen species in bacterial pathogenesis and host defense in C. elegans	17
Control of regulatory T cell homeostasis	17
Emerging dimensions of cellular cGAS-STING signaling	17
Dynamics of MHC-I molecules in the antigen processing and presentation pathway	16
BAFF signaling in B cell metabolism	16
Application of T cell receptor (TCR) repertoire analysis for the advancement of cancer immunotherapy	16
Neuron-intrinsic immunity to viruses in mice and humans	16
Indole derivatives, microbiome and graft versus host disease	16