OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Immunology is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection	354
The future of vaccination in Latin America: learning from the COVID-19 pandemic	102
Can juvenile idiopathic arthritis be cured?	101
TAP-ing into the cross-presentation secrets of dendritic cells	91
Oncogenic viruses, cancer biology, and innate immunity	84
Mechanistic insights into epigenetic contributions to psoriasis pathogenesis and their clinical implications	82
An easy pill to swallow: oral recombinant vaccines for the 21st century	70
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation	70
Principles and practical applications of structure-based vaccine design	62
Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy	61
Beyond the gastric epithelium — the paradox of Helicobacter pylori-induced immune responses	53
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity	53
Can we cure Behçet syndrome?	52
Commander-in-chief: monocytes rally the troops for defense against aspergillosis	51
B cell–targeted therapies in autoimmune skin disease: current advances and challenges	51
Neuropsychiatric lupus: a myriad of symptoms requires a myriad of models	48
Can sarcoidosis be cured?	46
Complement in antiphospholipid syndrome, time to target?	46
Some thoughts about what non-mammalian jawed vertebrates are telling us about antigen processing and peptide loading of MHC molecules	45
Necroptosis in immunity, tissue homeostasis, and cancer	41
Pharmacotherapeutic strategies to promote regulatory T cell function in autoimmunity	39
Innate antiviral immunity and immunometabolism in hepatocytes	36
Host genetics of innate immune system in infection	35
Metabolism and macrophages in the tumor microenvironment	35
Regulation of MHC class II and CD86 expression by March-I in immunity and disease	31

Nutritional modulation of antitumor immunity	30
Safety switches for adoptive cell therapy	30
Mapping and modelling human B cell maturation in the germinal centre	29
The epidermal immune microenvironment plays a central role in the pathogenesis of psoriasis	29
Mechanistic considerations linking SARS-CoV-2 infection, inflammation, and the loss of immune tolerance	28
Can we cure bullous skin diseases?	27
Immunological scars after cure of hepatitis C virus infection: Long‐HepC?	26
Patterns of bacterial viability governing noncanonical inflammasome activation	26
Editorial Board	25
Animal models of autoimmune encephalitis	25
T follicular helper cells and their impact on humoral responses during pathogen and vaccine challenge	24
Antibody glycosylation directs innate and adaptive immune collaboration	24
Game of Omes: ribosome profiling expands the MHC-I immunopeptidome	23
Bioinspired vaccines to enhance MHC class-I antigen cross-presentation	23
Harnessing IgG Fc glycosylation for clinical benefit	23
Editorial Board	23
Can we cure antiphospholipid syndrome?	23
Implication of epigenetic factors in development and recurrence of psoriasis	23
Resolving adjuvant mode of action to enhance vaccine efficacy	22
Application of T cell receptor (TCR) repertoire analysis for the advancement of cancer immunotherapy	22
Thetis cells: regulators of intestinal immune tolerance	21
Nucleic acid triggers of autoimmunity and autoinflammation	21
Outer membrane vesicle-based intranasal vaccines	21
Killing in self-defense: proapoptotic drugs to eliminate intracellular pathogens	20
Immune responses to Toxoplasma gondii	20
Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans	20
The increasing prevalence of autoimmunity and autoimmune diseases: an urgent call to action for improved understanding, diagnosis, treatment, and prevention	20
Intracellular complement in monocytes and macrophages: emerging roles	19
Neuroimmune crosstalk in the skin: a delicate balance governing inflammatory processes	19
Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity	19
Epigenetics: the link between environmental exposures and autoimmune diseases	18
Treating sarcoidosis: when less is more	18
HLA-B27 as a potential target for the cure of axial spondyloarthritis	18
cGAS-like receptor-mediated immunity: the insect perspective	17
Editorial Board	17
B cell memory of Immunoglobulin E (IgE) antibody responses in allergy	17
Rheumatoid arthritis — the role of T cells in this complex systemic autoimmune disease	17
New insights into the mechanisms regulating plasma cell survival and longevity	17
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment	16
‘Can we cure IgG4-related diseases?’	16
Mechanisms and risk factors for perinatal allergic disease	16
Tumor immune evasion through loss of MHC class-I antigen presentation	16
Can we cure lupus?	16
The role of CD4 T cells in rejection of solid tumors	16
Drivers and shapers of macrophages specification in the developing brain	16
IFNε, IFNω and IFNλ: interferons defending the mucosa	15
Autoimmunity, epitope analysis, and molecular mimicry	15
Eliciting or silencing complement activation: strategies for optimizing monoclonal antibodies functions	15
The role of epigenetic modifications in systemic autoinflammatory diseases	15
Regulation of inflammation by Interleukin-10 in the intestinal and respiratory mucosa	15

Defining the niche for stem-like CD8+ T cell formation and function	15
Regulation of type I and type III interferon induction in response to pathogen sensing	15
Red blood cell alloimmunization immunogenetic risk factor	14
TH17 cell immune adaptation	14
Immunometabolic regulation of germinal centers and its implications for aging	14
Advances and challenges in investigating B-cells via single-cell transcriptomics	14
Challenges in diagnosis of sarcoidosis	14
Publisher's Note	14
Major histocompatibility complex class II in the tumor microenvironment: functions of nonprofessional antigen-presenting cells	14
The thymoproteasome in shaping the CD8+ T-cell repertoire	14
New insights and approaches for analyses of immunopeptidomes	14
The role of epigenetics in inflammatory memory	14
PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis	14
Layers of defense: protection from respiratory viruses by epithelial-intrinsic immunity	14
Editorial overview: Tumour immunology: Engineered T cell therapy of cancer: current success and future improvements	13
Functional flexibility and plasticity in immune control of systemic Salmonella infection	13
Editorial Board	13
Inflammation induced by lipid mediators and protein from transfusion products	13
Differential signaling by type-I and type-III interferons in mucosa	13
HyperIgE in hypomorphic recombination-activating gene defects	13
T follicular helper cells in food allergy	13
Editorial overview: Special section neuroimmunology: Neuroimmune interactions in health and disease	13
The choroid plexus in inflammatory and degenerative diseases of the central nervous system	13
Curing inflammatory bowel diseases: breaking the barriers of current therapies– emerging strategies for a definitive treatment	13
Microbiota and B-1 B cell repertoire development in mice	13
Inherited human ZNF341 deficiency	13