OOIR: Observatory of International Research

Papers

(The median citation count of Prostaglandins Leukotrienes and Essential Fatty Acids is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Blood omega-3 fatty acids and death from COVID-19: A pilot study	82
Influence of the nutritional status and oxidative stress in the desaturation and elongation of n-3 and n-6 polyunsaturated fatty acids: Impact on non-alcoholic fatty liver disease	50
Linoleic acid and the regulation of glucose homeostasis: A review of the evidence	43
Polyunsaturated fatty acid biosynthesis pathway and genetics. implications for interindividual variability in prothrombotic, inflammatory conditions such as COVID-19✰,✰✰,★,★★	43
Dose- and time-dependent increase in circulating anti-inflammatory and pro-resolving lipid mediators following eicosapentaenoic acid supplementation in patients with major depressive disorder and chro	41
Omega-3 and omega-6 fatty acids have distinct effects on endothelial fatty acid content and nitric oxide bioavailability	35
Association between 19 dietary fatty acids intake and rheumatoid arthritis: Results of a nationwide survey	27
Red blood cell fatty acid patterns from 7 countries: Focus on the Omega-3 index	25
Exploring the role of LC-PUFA metabolism in pregnancy complications	24
PUFA, genotypes and risk for cardiovascular disease	23
The effects of omega-3 fatty acids in type 2 diabetes: A systematic review and meta-analysis	23
Palmitoleic acid ameliorates palmitic acid-induced proinflammation in J774A.1 macrophages via TLR4-dependent and TNF-α-independent signallings	22
Altered tissue specialized pro-resolving mediators in chronic rhinosinusitis	21
A biological rationale for the disparate effects of omega-3 fatty acids on cardiovascular disease outcomes	20
The effect of a 6-month ketogenic medium-chain triglyceride supplement on plasma cardiometabolic and inflammatory markers in mild cognitive impairment.	19
Associations between red blood cells fatty acids, desaturases indices and metabolism of platelet activating factor in healthy volunteers	19
ISSFAL statement number 7 – Omega-3 fatty acids during pregnancy to reduce preterm birth	17
n-3 polyunsaturated fatty acids in the regulation of adipose tissue browning and thermogenesis in obesity: Potential relationship with gut microbiota	14
Long chain omega-3 fatty acids and their oxidized metabolites are associated with reduced prostate tumor growth	14
Analysis of major fatty acids from matched plasma and serum samples reveals highly comparable absolute and relative levels	14
Lipids in the origin of intracellular detail and speciation in the Cambrian epoch and the significance of the last double bond of docosahexaenoic acid in cell signaling	13
Regional similarities and differences in mature human milk fatty acids in Chinese population: A systematic review	13
Dietary supplementation with docosahexaenoic acid rich fish oil increases circulating levels of testosterone in overweight and obese men	13
The association between a Fatty Acid Binding Protein 1 (FABP1) gene polymorphism and serum lipid abnormalities in the MASHAD cohort study	12
Effect of one year krill oil supplementation on depressive symptoms and self-esteem of Dutch adolescents: A randomized controlled trial	12

Gestational diabetes mellitus decreased umbilical cord blood polyunsaturated fatty acids: a meta-analysis of observational studies	12
Effect of n-3 polyunsaturated fatty acid supplementation on muscle mass and function with aging: A meta-analysis of randomized controlled trials✰	11
Long-term docosahexaenoic acid (DHA) supplementation in cystic fibrosis patients: a randomized, multi-center, double-blind, placebo-controlled trial	10
Resolvin D1 reduces inflammation in co-cultures of primary human macrophages and adipocytes by triggering macrophages	10
Impact of the Mediterranean Dietary pattern on n-3 fatty acid tissue levels–A systematic review.	10
Effects of long-chain omega-3 polyunsaturated fatty acids on reducing anxiety and/or depression in adults; A systematic review and meta-analysis of randomised controlled trials	10
Differences in erythrocyte phospholipid membrane long-chain polyunsaturated fatty acids and the prevalence of fatty acid desaturase genotype among African Americans and European Americans	10
The aromatase inhibitor letrozole restores FADS2 function in ER+ MCF7 human breast cancer cells	9
Circulating polyunsaturated fatty acids, pressure pain thresholds, and nociplastic pain conditions	9
Acute injection of a DHA triglyceride emulsion after hypoxic-ischemic brain injury in mice increases both DHA and EPA levels in blood and brain✰	9
Plasma and rectal mucosal oxylipin levels during aspirin and eicosapentaenoic acid treatment in the seAFOod polyp prevention trial	9
Regulation of the cytochrome P450 epoxyeicosanoid pathway is associated with distinct histologic features in pediatric non-alcoholic fatty liver disease	9
Validation of an abbreviated food frequency questionnaire for estimating DHA intake of pregnant women in the United States	9
Genetic and environmental influences on serum oxylipins, endocannabinoids, bile acids and steroids	9
Addition of EP2 agonists to an FP agonist additively and synergistically modulates adipogenesis and the physical properties of 3D 3T3-L1 sphenoids	8
Prostaglandin and prostamide concentrations in amniotic fluid of women with spontaneous labor at term with and without clinical chorioamnionitis	8
The endocannabinoids anandamide and 2-arachidonoylglycerol modulate the expression of angiogenic factors on HTR8/SVneo placental cells	8
The role of peripheral fatty acids as biomarkers for Alzheimer's disease and brain inflammation	8
Associations of umbilical cord fatty acid profiles and desaturase enzyme indices with birth weight for gestational age in Japanese infants	8
Long-chain Omega-3 fatty acids supplementation and cognitive performance throughout adulthood: A 6-month randomized controlled trial.	8
Regulative effect of maternal serum fatty acid-binding protein 4 on insulin resistance and the development of gestational diabetes mellitus	8
Feeding regulation by oleoylethanolamide synthesized from dietary oleic acid	8
Levels of eicosanoids in nasal secretions associated with nasal polyp severity in chronic rhinosinusitis	8
Over-the-counter fish oil supplementation and pro-resolving and pro-inflammatory lipid mediators in rheumatoid arthritis	8
Lipid mediator profiles of burn wound healing: Acellular cod fish skin grafts promote the formation of EPA and DHA derived lipid mediators following seven days of treatment	7
Profiling the expression of fatty acid-binding proteins and fatty acid transporters in mouse microglia and assessing their role in docosahexaenoic acid-d5 uptake	7
The major endocannabinoid anandamide (AEA) induces apoptosis of human granulosa cells	7
Comparison of human and rodent cell models to study myocardial lipid-induced insulin resistance	7
Omega-3 index is directly associated with a healthy red blood cell distribution width	7
The omega-3 index is inversely associated with the neutrophil-lymphocyte ratio in adults’	7
A high sucrose diet modifies brain oxylipins in a sex-dependent manner	7
In pregnancy, maternal HDL is specifically enriched in, and carries the highest proportion of, DHA in plasma	7
Omega-3 index and type 2 diabetes: Systematic review and meta-analysis	7
Harmonizing blood DHA levels in pregnancy studies: An interlaboratory investigation	7
Rationale and design of a randomized controlled trial examining the effects of marine- and plant-sourced omega-3 fatty acid supplements on octadecanoid profiles and inflammation in females with obesit	6
N-3 Polyunsaturated fatty acid ethyl esters decrease the invasion, but not the proliferation, of human colorectal cancer cells via a PI3K-dependent mechanism in vitro	6
Plasma oxylipin levels associated with preterm birth in preterm labor✰	6
Stable analogs of 13‑hydroxy-9,10-trans-epoxy-(11E)-octadecenoate (13,9-HEL), an oxidized derivative of linoleic acid implicated in the epidermal skin barrier	6
Non-esterified fatty acids as biomarkers of diet and glucose homeostasis in pregnancy: The impact of fatty acid reporting methods	6
Increases in plasma n-3 tetracosapentaenoic acid and tetracosahexaenoic acid following 12 weeks of EPA, but not DHA, supplementation in women and men	6
Inhalation of nebulized omega-3 fatty acids mitigate LPS-induced acute lung inflammation in rats: Implications for treatment of COPD and COVID-19	6
Statin therapy upregulates arachidonic acid status via enhanced endogenous synthesis in patients with plaque psoriasis	6
Palmitic acid methyl ester inhibits cardiac arrest-induced neuroinflammation and mitochondrial dysfunction	6
Effect of omega-3 lcpufa supplementation on maternal fatty acid and oxylipin concentrations during pregnancy	6
Endogenous ω-3 fatty acids in Fat-1 mice attenuated depression-like behaviors, spatial memory impairment and relevant changes induced by olfactory bulbectomy	6
Beneficial effect of long-chain n-3 polyunsaturated fatty acid supplementation on tuberculosis in mice	6
Development of a novel database to review and assess the clinical effects of EPA and DHA omega-3 fatty acids	6
Supplemental dietary oils rich in oleic acid or linoleic acid attenuate egg yolk and tissue n-3 polyunsaturated fatty acid contents in laying hens co-fed oils enriched in either stearidonic acid or α-	6
Effects of uric acid on oxidative and nitrosative stress and other related parameters in SH-SY5Y human neuroblastoma cells.	6
Effect of omega-3 fatty acid supplementation on telomere length and telomerase activity: A systematic review of clinical trials	5

The effects of perioperative dexamethasone on eicosanoids and mediators of inflammation resolution: A sub-study of the PADDAG trial	5
Low LXA4, RvD1 and RvE1 levels may be an indicator of the development of hypertension	5
Omega-3 polyunsaturated fatty acid intake and plasma fatty acids of school going Indian children - a cross-sectional study	5
Soluble epoxide hydrolase as a therapeutic target for obesity-induced disorders: roles of gut barrier function involved	5
Assessment of polyunsaturated fatty acids: A self-report and biomarker assessment with a racially and ethnically diverse sample of women	5
Effect of parenteral lipid emulsion on preterm infant PUFAs and their downstream metabolites	5
Baseline red blood cell and breast milk DHA levels affect responses to standard dose of DHA in lactating women on a controlled feeding diet	5
Fatty acid metabolism is involved in both retinal physiology and the pathology of retinal vascular diseases	5
Translating n-3 polyunsaturated fatty acid status from whole blood to plasma and red blood cells during pregnancy	5
Omega 6 polyunsaturated fatty acids in red blood cell membrane are associated with xerostomia and taste loss in patients with breast cancer	5
Prostaglandins as potential targets for the treatment of polycystic kidney disease	5
Plasma omega-3 is not associated with appendicular muscle mass index in young and middle-aged individuals: Results from NHANES 2011-2012	5
Blood fatty acid analysis reveals similar n-3 fatty acid composition in non-pregnant and pregnant women and their neonates in an Israeli pilot study	4
Evidence of multiple hepatic mechanisms to mobilize docosahexaenoic acid into dam plasma during pregnancy in chow-fed sprague dawley rats	4
Influence of ω3 fatty acids on maternal behavior and brain oxytocin in the murine perinatal period	4
Aspirin and omega-3 fatty acid status interact in the prevention of cardiovascular diseases in Framingham Heart Study	4
Effect of fasting status and other pre-analytical variables on quantitation of long-chain fatty acids in red blood cells	4
Higher omega-3 index is associated with more rapid heart rate recovery in healthy men and women	4
Alterations in hepatic fatty acids reveal depletion of total polyunsaturated fatty acids following irinotecan plus 5-fluorouracil treatment in an animal model of colorectal cancer	4
Higher n-3 polyunsaturated fatty acid status during early pregnancy is associated with lower risk for depression at 12 months postpartum: The NuPED study	4
Association of placental fatty acid desaturase 2 (FADS2) methylation with maternal fatty acid levels in women with preeclampsia	4
Prostaglandin F2α in vitro can affect basic inflammatory parameters of mesenchymal stem cells and slight modulating some of their immunomodulatory properties	4
Effect of dietary n-3 polyunsaturated fatty acids on the composition of cecal microbiome of Lohmann hens	4
Polyunsaturated fatty acids as predictors of future suicide attempt	4
Utility of a 7- question online screener for DHA intake	4
The biological actions of prostanoids in adipose tissue in physiological and pathophysiological conditions	3
Deletion of the gene encoding prostamide/prostaglandin F synthase reveals an important role in regulating intraocular pressure	3
SPM pathway marker analysis of the brains of obese mice in the absence and presence of eicosapentaenoic acid ethyl esters	3
Maternal vitamin D deficiency reduces docosahexaenoic acid, placental growth factor and peroxisome proliferator activated receptor gamma levels in the pup brain in a rat model of preeclampsia	3
An open-label, multicenter, phase 2 study of a food enriched with docosahexaenoic acid in adults with sickle cell disease	3
Oxylipin status, before and after LC n-3 PUFA supplementation, has little relationship with skeletal muscle biology in older adults at risk of sarcopenia	3
Specialized pro-resolvin mediators induce cell growth and improve wound repair in intestinal epithelial Caco-2 cell cultures	3
Body surface area-based omega-3 fatty acids supplementation strongly correlates to blood concentrations in children.	3
Non-esterified erythrocyte linoleic acid, arachidonic acid, and subjective sleep outcomes	3
Effect of omega-6 linoleic acid on neurobehavioral development in Caenorhabditis elegans	3
Polymorphisms rs2745557 in PTGS2 and rs2075797 in PTGER2 are associated with the risk of chronic obstructive pulmonary disease development in a Tunisian cohort	3
The prohibitin complex regulates macrophage fatty acid composition, plasma membrane packing, and lipid raft-mediated inflammatory signaling	3
Virtual non-compliance with Omega-3 treatment results in null effects: The RANGER study	3
Secondary data analysis investigating effects of marine omega-3 fatty acids on circulating levels of leptin and adiponectin in older adults	3
A rapid method for the screening of fatty acids in lipids in plasma or serum without prior extraction	2
Neurodevelopment, nutrition and genetics. A contemporary retrospective on neurocognitive health on the occasion of the 100th anniversary of the National Institute of Nutrition, Hyderabad, India	2
Breastmilk PUFA strongly associated with maternal dietary intake but not anthropometric parameters and breastmilk carotenoids	2
The effect of α-linolenic acid enrichment in perinatal diets in preventing high fat diet-induced SCD1 increased activity and lipid disarray in adult offspring of low density lipoprotein receptor knock	2
New β-ketophosphonates for the synthesis of prostaglandin analogues. 1. Phosphonates with a bicyclo[3.3.0]octene scaffold spaced by a methylene group from the β-ketone	2
Lipopolysaccharide stimulates bovine endometrium explants through toll‑like receptor 4 signaling and PGE2 synthesis	2
Relationship between the combination of polyunsaturated fatty acids intake and psychological distress during pregnancy: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study	2
Dietary omega-3 fatty acid deficiency from pre-pregnancy to lactation affects expression of genes involved in hippocampal neurogenesis of the offspring	2
Placental F4-Neuroprostanes and F2-Isoprostanes are altered in gestational diabetes mellitus and maternal obesity	2
Fish oil supplementation enhances colon recovery after experimental colitis	2
Radiosynthesis of 20-[18F]fluoroarachidonic acid for PET-MR imaging: Biological evaluation in ApoE4-TR mice	2
Hemodialysis and biotransformation of erythrocyte epoxy fatty acids in peripheral tissue	2
Plasma fatty acid responses to a calorie-restricted, DASH-style diet with lean beef	2
Dietary fat content and adipose triglyceride lipase and hormone-sensitive lipase gene expressions in adults’ subcutaneous and visceral fat tissues	2
Effect of a pescetarian and vegan diet on fatty acid composition in blood and spermatozoa in young healthy men	2
The influence of DHA supplementation during pregnancy on language development across childhood: Follow-up of a randomised controlled trial	2
Enteral supplementation with arachidonic and docosahexaenoic acid and pulmonary outcome in extremely preterm infants	2
Profiling of lipid mediators in atherosclerotic carotid plaques from type 2 diabetic and non-diabetic patients.	2
Association between maternal obesity, essential fatty acids and biomarkers of fetal liver function	2
Plasma fatty acid abnormality in Sudanese drug-resistant epileptic patients	2