Phytotherapy Research

Papers
(The median citation count of Phytotherapy Research is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Autophagy inhibition enhances anti‐pituitary adenoma effect of tetrandrine269
Curculigoside rescues hippocampal synaptic deficits elicited by PTSD through activating cAMP‐PKA signaling244
Evaluation of the effect of Lepidium meyenii Walpers in infertile patients: A randomized, double‐blind, placebo‐controlled trial147
Effects of different natural products in patients with non‐alcoholic fatty liver disease—A network meta‐analysis of randomized controlled trials134
Efficacy of frankincense‐based herbal product in urinary incontinence: A randomized, double‐blind, placebo‐ and active‐controlled clinical trial125
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Dietary plants for oral cancer prevention and therapy: A review of preclinical and clinical studies108
Morin attenuates osteoclast formation and function by suppressing the NF‐κB, MAPK and calcium signalling pathways96
Pharmacovigilance of unlicensed cannabidiol in European countries91
Safety assessment and adverse drug reaction reporting of tea tree oil (Melaleuca aetheroleum)91
Phytoncides could potentially inhibit the spike protein of SARS‐CoV‐2 variants89
Astragaloside IV Alleviates Acute Hepatic Injury by Regulating Macrophage Polarization and Pyroptosis via Activation of the AMPK/SIRT1 Signaling Pathway85
Preclinical studies of the antitumor effect of curcumin‐loaded polymeric nanocapsules: A systematic review and meta‐analysis83
Maltol mitigates cisplatin‐evoked cardiotoxicity via inhibiting the PI3K/Akt signaling pathway in rodents in vivo and in vitro83
Co‐administration of sub‐effective doses of the constituents of Crocus sativus L. crocins with those of the antipsychotics clozapine and risperidone counteract memory deficits caused by blockad82
RETRACTION: Epigallocatechin‐3‐Gallate Enhances Differentiation of Acute Promyelocytic Leukemia Cells via Inhibition of PMLRARα and HDAC182
Antiplatelet effect of ginkgo diterpene lactone meglumine injection in acute ischemic stroke: A randomized, double‐blind, placebo‐controlled clinical trial81
Licarin A, a neolignan isolated from Nectandra oppositifolia Nees & Mart. (Lauraceae), exhibited moderate preclinical efficacy against Schistosoma mansoni infection80
Xanthohumol Regulates Mitophagy in Osteosarcoma Cells via AMPKULK1FUNDC1 Signaling Pathway78
Curcumin as a therapeutic agent in cancer therapy: Focusing on its modulatory effects on circularRNAs78
Natural compounds as obesity pharmacotherapies73
The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double‐blind, controlled trial72
The effect of propolis supplementation on cardiovascular risk factors in women with rheumatoid arthritis: A double‐blind, placebo, controlled randomized clinical trial69
Schisandra B, a representative lignan from Schisandra chinensis, improves cisplatin‐induced toxicity: An in vitro study68
Bryodulcosigenin attenuates bleomycin‐induced pulmonary fibrosis via inhibiting AMPK‐mediated mesenchymal epithelial transition and oxidative stress68
Phase III randomized clinical trial of BV‐4051, an Ayurvedic polyherbal formulation in moderate SARS‐CoV‐2 infections and its impact on inflammatory biomarkers65
The influence of propolis plus Hyoscyamus niger L. against COVID‐19: A phase II, multicenter, placebo‐controlled, randomized trial62
Vegetable‐derived indole enhances the melanoma‐treating efficacy of chemotherapeutics62
Ethanol extract of Pueraria lobata improve acute myocardial infarction in rats via regulating gut microbiota and bile acid metabolism62
Phytochemicals targeting ferroptosis in cardiovascular diseases: Recent advances and therapeutic perspectives61
Anti‐Warburg effect via generation of ROS and inhibition of PKM2/β‐catenin mediates apoptosis of lambertianic acid in prostate cancer cells59
Ellagitannin Component Punicalin Ameliorates Cognitive Dysfunction, Oxidative Stress, and Neuroinflammation via the Inhibition of cGASSTING Signaling in the Brain of an Aging Mo59
Effects of gypenoside L‐containingGynostemma pentaphyllumextract on fatigue and physical performance: A double‐blind, placebo‐controlled, randomized trial57
Saponin monomers: Potential candidates for the treatment of type 2 diabetes mellitus and its complications57
Polysaccharides (pectin, mucilage, and fructan inulin) and their fermented products: A critical analysis of their biochemical, gut interactions, and biological functions as antidiabetic agents56
Polydatin as a therapeutic alternative for central nervous system disorders: A systematic review of animal studies54
Effects of artichoke leaf extract supplementation or artichoke juice consumption on lipid profile: A systematic review and dose–response meta‐analysis of randomized controlled trials53
Morus alba L. water extract changes gut microbiota and fecal metabolome in mice induced by high‐fat and high‐sucrose diet plus low‐dose streptozotocin50
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Upregulation of key factors of viral entry of corona‐ and influenza viruses upon TLR3‐signaling in cells from the respiratory tract and clinical treatment options by 1,8‐Cineol47
The alleviative effect of flavonol‐type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders47
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Hyperoside prevents doxorubicin‐induced cardiotoxicity by inhibiting NOXs/ROS/NLRP3 inflammasome signaling pathway46
Jatrorrhizine alleviates cytokine storm secondary lung injury via regulating CD39‐dominant purinergic braking and downstream NLRP3 inflammasome46
Mechanisms and Potential of Antitumor Therapy With Natural Products Regulating Non‐Coding RNAs45
Bavachinin selectively modulates PPAR γ and maintains bone homeostasis in Type 2 Diabetes45
Brazilian red propolis exerts a cytotoxic action against prostate cancer cells and upregulates human monocyte functions45
Exploring the therapeutic implications of natural compounds modulating apoptosis in vascular dementia45
Effect of curcumin on C‐reactive protein as a biomarker of systemic inflammation: An updated meta‐analysis of randomized controlled trials43
Costunolide protects against alcohol‐induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro43
Aromatic monophenols from cinnamon bark act as proteasome inhibitors by upregulating ER stress, suppressing FoxM1 expression, and inducing apoptosis in prostate cancer cells43
Effects of orange juice intake on cardiovascular risk factors: A systematic review and meta‐analysis of randomized controlled clinical trials42
Cardiovascular benefits of Eruca sativa mill. Defatted seed meal extract: Potential role of hydrogen sulfide42
The effects of Garcinia cambogia (hydroxycitric acid) on lipid profile: A systematic review and meta‐analysis of randomized controlled trials41
Therapeutic Potential of Chinese Herbal Medicine and Underlying Mechanism for the Treatment of Myocardial Infarction41
Mitochondrial‐targeted curcumin inhibits T‐cell activation via Nrf2 and inhibits graft‐versus‐host‐disease in a mouse model41
SH‐PRO extract alleviates benign prostatic hyperplasia via ROS‐mediated activation of PARP/caspase 3 and inhibition of FOXO3a/AR/PSA s41
Immunostimulant plant proteins: Potential candidates as vaccine adjuvants41
Substantial Effects of Carotenoids on Skin Health: A Mechanistic Perspective40
Ouratein D, a Biflavanone From Ouratea spectabilis, Alleviates Betacoronavirus Infection by Mitigating Inflammation, Lung Damage and Viral Replication40
Quercetin as a protective agent for liver diseases: A comprehensive descriptive review of the molecular mechanism39
Urolithin A alleviates acute kidney injury induced by renal ischemia reperfusion through the p62‐Keap1‐Nrf2 signaling pathway39
Asiatic acid inhibits angiogenesis and vascular permeability through the VEGF/VEGFR2 signaling pathway to inhibit the growth and metastasis of breast cancer in mice38
Nootkatone alleviates rotenone‐induced Parkinson's disease symptoms through activation of the PI3K/Akt signaling pathway38
A grape (Vitis vinifera L.) pomace water extract modulates inflammatory and immune response in SW‐480 cells and isolated mouse colon38
Curcumin–cisplatin chemotherapy: A novel strategy in promoting chemotherapy efficacy and reducing side effects38
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Trilobatin promotes angiogenesis after cerebral ischemia–reperfusion injury via SIRT7/VEGFA signaling pathway in rats38
Fangchinoline abrogates growth and survival of hepatocellular carcinoma by negative regulation of c‐met/HGF and its associated downstream signaling pathways38
Jaridon 6, a new diterpene from Rabdosia rubescens (Hemsl.) Hara, can display anti‐gastric cancer resistance by inhibiting SIRT1 and inducing autophagy37
Pharmacogenetic‐based management of depression: Role of traditional Persian medicine37
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Traditional medicinal plants in the treatment of gastrointestinal parasites in humans: A systematic review and meta‐analysis of clinical and experimental evidence36
Phytocompounds and COVID‐19: Two years of knowledge36
Peiminine regulates bone‐fat balance by canonical Wnt/β‐catenin pathway in an ovariectomized rat model35
Neuroinflammation inhibition and neuroprotective effects of purpurin, a potential anti‐AD compound, screened via network proximity and gene enrichment analyses35
Resistant starch from black rice, Oryza sativaL. var. ameliorates renal inflammation, fibrosis and injury in insulin resistant rats35
Ginkgo Flavone Aglycone Ameliorates Atherosclerosis via Inhibiting Endothelial Pyroptosis by Activating the Nrf2 Pathway35
Chemical constituents, biological activities and anti‐rheumatoid arthritic properties of four citrus essential oils35
Effect of walnut consumption on markers of endothelial function in adults: A systematic review and meta‐analysis of randomized controlled trials35
Pharmacologic activities of phytosteroids in inflammatory diseases: Mechanism of action and therapeutic potentials34
Natural products targeting macroautophagy signaling in hepatocellular carcinoma therapy: Recent evidence and perspectives34
Trifolirhizin reduces osteoclast formation and prevents inflammatory osteolysis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signaling pathways and ROS34
Exploiting new strategies in combating head and neck carcinoma: A comprehensive review on phytochemical approaches passing through PI3K/Akt/mTOR signaling pathway33
Withanolides: Promising candidates for cancer therapy33
Astragaloside IV ameliorates radiation‐induced nerve cell damage by activating the BDNF/TrkB signaling pathway33
Rosa Damascena mill for treating adults' anxiety, depression, and stress: A systematic review and dose–response meta‐analysis of randomized controlled trials33
Columbianadin Ameliorates Myocardial Injury by Inhibiting Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in AMI Mice and Hypoxic H9c2 Cells33
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Effects of ginseng consumption on the biomarkers of oxidative stress: A systematic review and meta‐analysis32
Therapeutic considerations of bioactive compounds in Alzheimer's disease and Parkinson's disease: Dissecting the molecular pathways32
Pterostilbene Exhibits Broad‐Spectrum Antiviral Activity by Targeting the Enterovirus Capsid, Inactivating Viral Particles, Blocking Viral Binding, and Protecting Mice From Lethal EVA32
Antitumor effect of luteolin proven by patient‐derived organoids of gastric cancer32
Helichrysum stoechas (L.) Moench reduces body weight gain and modulates mood disorders via inhibition of silent information regulator 1 (SIRT1) by arzanol32
Formononetin attenuates cigarette smoke‐induced COPD in mice by suppressing inflammation, endoplasmic reticulum stress, and apoptosis in bronchial epithelial cells via AhR/C32
Gut microbiota, bile acids, and nature compounds31
A randomized, double‐blind, placebo‐controlled study of Cistanche tubulosa and Ginkgo biloba extracts for the improvement of cognitive function in middle‐aged and elderly people31
Curcumin supplementation as a complementary and alternative medicine for COVID‐19 patients31
Formononetin Induces Ferroptosis in Activated Hepatic Stellate Cells to Attenuate Liver Fibrosis by Targeting NADPH Oxidase 431
The effects of lycopene supplementation on insulin‐like growth factor‐1 and insulin‐like growth factor binding proteins: A systematic review of randomized controlled trials31
Current clinical developments in curcumin‐based therapeutics for cancer and chronic diseases31
Lotusine ameliorates propionic acid‐induced autism spectrum disorder‐like behavior in mice by activating D1 dopamine receptor in medial prefrontal cortex31
Effects of Dietary Polyphenols on Vasculogenic Erectile Dysfunction: A Systematic Review of Pre‐Clinical Studies31
Efficacy of herbal treatments for functional dyspepsia: A systematic review and meta‐analysis of randomized clinical trials31
Efficacy of Extracts of Oleogum Resin of Boswellia in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta‐Analysis30
miRNA, phytometabolites and disease: Connecting the dots30
Acetylshikonin Derived From Arnebia euchroma (Royle) Johnst Kills Multidrug‐Resistant Gram‐Positive Pathogens In Vitro and In Vivo30
An exploratory double‐blind, randomized, placebo‐controlled study to assess the efficacy of CitruSlim on body composition and lipid parameters in obese individuals30
Is the mushroom Meripilus giganteus a potential cancer chemopreventive agent?30
Tetrandrine Alleviates Pulmonary Fibrosis by Modulating Lung Microbiota‐Derived Metabolism and Ameliorating Alveolar Epithelial Cell Senescence30
Therapeutic effect of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. leaves on ischemic stroke via the microbiota–gut–brain axis30
Natural products in suppressing glioma progression: A focus on the role of microRNAs30
Curcumin and nano‐curcumin applications in psychiatric disorders29
The effect of saffron (Crocus sativus L.) on glycemia, lipid profile, and antioxidant status in patients with type‐2 diabetes mellitus: A randomized placebo‐controlled trial29
Effect of sumac powder on clinical symptoms, hyperandrogenism, inflammation, blood glucose, lipid profiles in women with polycystic ovary syndrome: A double‐blind randomized clinical trial29
What is the influence of cinnamon supplementation on liver enzymes? A systematic review and meta‐analysis of randomized controlled trials29
Hypoglycemic Effect of Ginsenoside Compound K Mediated by N‐Acetylserotonin Derived From Gut Microbiota29
Artemether Ameliorates Non‐Alcoholic Steatohepatitis by Restraining Cross‐Talk Between Lipotoxicity‐Induced Hepatic Hepatocytes and Macrophages29
Anthocyanin oligomers stimulate browning in 3T3‐L1 white adipocytes via activation of the β3‐adrenergic receptor and ERK signaling pathway29
Effects of resveratrol on female reproduction: A review29
The efficacy of curcumin supplementation on serum total antioxidant capacity, malondialdehyde, and disease activity in women with rheumatoid arthritis: A randomized, double‐blind, placebo‐controlled c28
The effects of flavonoids in experimental sepsis: A systematic review and meta‐analysis28
Cornuside, by regulating the AGEs‐RAGE‐IκBα‐ERK1/2 signaling pathway, ameliorates cognitive impairment associated with brain aging28
Increasing brain glucose uptake by Gypenoside LXXV ameliorates cognitive deficits in a mouse model of diabetic Alzheimer's disease28
Phytosomes as a New Frontier and Emerging Nanotechnology Platform for Phytopharmaceuticals: Therapeutic and Clinical Applications28
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Magnolol alleviates pulmonary fibrosis inchronic obstructive pulmonary disease by targeting transient receptor potential vanilloid 4‐ankyrin repeat domain28
Xanthotoxin (8‐methoxypsoralen): A review of its chemistry, pharmacology, pharmacokinetics, and toxicity28
Systematic Review and Network Meta‐Analysis of the Effects of Plant Extracts on Cognitive Function and Quality of Life in Stroke Patients27
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Combination of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos improves cardiac function of diabetic cardiomyopathy mice by regulating the unfolded protein response signaling pathway27
Sinigrin Selectively Mitigates the Acute‐Cardiac Inflammatory Response Through an AMPK‐Dependent Mechanism27
Zeylenone synergizes with cisplatin in osteosarcoma by enhancing DNA damage, apoptosis, and necrosis via the Hsp90/AKT/GSK3β and Fanconi anaemia pathway27
Effects of Sumac Supplementation on Lipid Profile: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials26
Protective effects of 4‐geranyloxy‐2,6‐dihydroxybenzophenonel on DSS‐induced ulcerative colitis in mice via regulation of cAMP/PKA/CREB and NF‐κB26
Taxifolin‐mediated Nrf2 activation ameliorates oxidative stress and apoptosis for the treatment of glucocorticoid‐induced osteonecrosis of the femoral head26
Ursolic acid inhibits the activation of smoothened‐independent non‐canonical hedgehog pathway in colorectal cancer by suppressing AKT signaling cascade26
Phytochemicals mediated modulation of microRNAs and long non‐coding RNAs in cancer prevention and therapy26
Germacrone alleviates breast cancer‐associated osteolysis by inhibiting osteoclastogenesis via inhibition of MAPK/NF‐κB signaling pathways26
Perilla seed oil improves bone health by inhibiting bone resorption in healthy Japanese adults: A 12‐month, randomized, double‐blind, placebo‐controlled trial26
Unlocking the Therapeutic Potential of Autophagy Modulation by Natural Products in Tackling Non‐Alcoholic Fatty Liver Disease26
Tanshinone IIA improves contextual fear‐ and anxiety‐like behaviors in mice via the CREB/BDNF/TrkB signaling pathway26
Effects of adjuvant berberine therapy on acute ischemic stroke: A meta‐analysis25
Isoliquiritigenin Exhibits Anti‐Inflammatory Responses in Acute Lung Injury by Covalently Binding to the Myeloid Differentiation Protein‐2 Domain25
Curcumin suppressed the proliferation and apoptosis of HPV‐positive cervical cancer cells by directly targeting the E6 protein25
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Salidroside improves blood–brain barrier integrity and cognitive function in hypobaric hypoxia mice by inhibiting microglia activation through GSK3β25
A review on phytoestrogens: Current status and future direction25
Total flavonoids of Rhizoma drynariae promote angiogenesis and osteogenesis in bone defects25
Potential use of curcumin against methicillin‐resistant Staphylococcus infection25
Wogonin and its analogs for the prevention and treatment of cancer: A systematic review25
Total glucosides of white paeony capsule alleviate articular cartilage degeneration and aberrant subchondral bone remodeling in knee osteoarthritis25
Potato protease inhibitor II prevents obesity by inducing browning of white adipose tissue in mice via β3 adrenergic receptor signaling pathway25
The potential health benefits of aloin from genus Aloe25
Effectiveness of Curcuma longa extract versus placebo for the treatment of knee osteoarthritis: A systematic review and meta‐analysis of randomized controlled trials24
Medicinal herbs consumption in relation to cardiometabolic indices and coronary artery stenosis in participants undergoing coronary angiography: A cross‐sectional study24
Molecular dynamics simulation and in vitro evaluation of herb–drug interactions involving dietary polyphenols and CDK inhibitors in breast cancer chemotherapy24
The 6‐month effect of whole soy and purified isoflavones daidzein on thyroid functionA double‐blind, randomized, placebo controlled trial among Chinese equol‐producing po24
Curdione inhibits ferroptosis in isoprenaline‐induced myocardial infarction via regulating Keap1/Trx1/GPX4 signaling pathway24
Pomegranate polyphenol punicalagin improves learning memory deficits, redox homeostasis, and neuroinflammation in aging mice24
The role of natural products as PCSK9 modulators: A review24
Beneficial effects of Ginkgo biloba leaf extract on inflammatory markers: A systematic review and meta‐analysis of the clinical trials24
Pomegranate effects on the health aspects of women during peri‐ and postmenopause: A systematic review and meta‐analysis23
Integrated Microbiome and Metabolomic to Explore the Mechanism of Coptisine in Alleviating Ulcerative Colitis23
Tussilagone ameliorates high‐fat diet‐induced hepatic steatosis by enhancing energy metabolism and antioxidant activity23
Poncirus trifoliata Extract and Its Active Coumarins Alleviate Dexamethasone‐Induced Skeletal Muscle Atrophy by Regulating Protein Synthesis, Mitochondrial Biogenesis, and Gut Microb23
Effects of licorice root supplementation on liver enzymes, hepatic steatosis, metabolic and oxidative stress parameters in women with nonalcoholic fatty liver disease: A randomized double‐blind clinic22
Resveratrol and endoplasmic reticulum stress: A review of the potential protective mechanisms of the polyphenol22
Ameliorative effect ofLuffa cylindricafruits onCaenorhabditis elegansand cellular models of Alzheimer's disease‐related pathology via autophagy induction22
Pharmacodynamics of Aloe vera and acemannan in therapeutic applications for skin, digestion, and immunomodulation22
Licochalcone A inhibits MAS‐related GPR family member X2‐induced pseudo‐allergic reaction by suppressing nuclear migration of nuclear factor‐κB22
Effects of sea buckthorn (Hippophae rhamnoides L.) on factors related to metabolic syndrome: A systematic review and meta‐analysis of randomized controlled trial22
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Naringin protects against inflammation and apoptosis induced by intestinal ischemia–reperfusion injury through deactivation of cGAS‐STING signaling pathway22
Paeoniflorin‐6′‐O‐benzene sulfonate protected the intestinal epithelial barrier by restoring the inhibitory effect of GRK2 and β‐arrestin 2 on ERK1/2‐NF‐κB22
Molecular updates on berberine in liver diseases: Bench to bedside22
Trilobolide‐6‐O‐isobutyrate suppresses hepatocellular carcinoma tumorigenesis through inhibition of IL‐6/STAT3 signaling pathway22
Therapeutic effect of curcumin in gastrointestinal cancers: A comprehensive review22
Maslinic Acid Ameliorates DSS‐Induced Experimental Colitis by Suppressing Th Cell‐Mediated Inflammation via AICD Induction22
The therapeutic effects of berberine against different diseases: A review on the involvement of the endoplasmic reticulum stress22
Pretreatment with Notoginsenoside R1 attenuates high‐altitude hypoxia‐induced cardiac injury via activation of the ERK1/2‐P90RSK‐Bad signaling pathway in rats22
Corosolic acid ameliorates non‐alcoholic steatohepatitis induced by high‐fat diet and carbon tetrachloride by regulating TGF‐β1/Smad2, NF‐κB, and AMPK signaling pathwa22
Plant‐derived virulence arresting drugs as novel antimicrobial agents: Discovery, perspective, and challenges in clinical use22
Cancer metabolism control by natural products: Pyruvate kinase M2 targeting therapeutics22
A comprehensive review of antitumor properties of Angelica species and their antitumor‐responsible constituents and the underlying molecular mechanisms involved in tumor inhibition21
Anticancer and chemopreventive potential of Morinda citrifolia L. bioactive compounds: A comprehensive update21
A Marine‐Derived Small Molecule Inhibits Prostate Cancer Growth by Promoting Endoplasmic Reticulum Stress Induced Apoptosis and Autophagy21
Advances in Research on Marine Natural Products for Modulating the Inflammatory Microenvironment21
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Hepatoprotective effect of dietary pterostilbene against high‐fat‐diet‐induced lipid accumulation exacerbated by chronic jet lag via SIRT1 and SIRT3 activation21
Antcin A, a phytosterol regulates SARS‐CoV‐2 spike protein‐mediated metabolic alteration in THP‐1 cells explored by the 1H‐NMR‐based metabolomics approach21
Cannabidiol tempers alcohol intake and neuroendocrine and behavioural correlates in alcohol binge drinking  adolescent rats. Focus on calcitonin gene‐related peptide's brain levels21
Thymol inTrachyspermum ammiseed extract exhibits neuroprotection, learning, and memory enhancement in scopolamine‐induced Alzheimer's disease mouse model21
Yerba mate (Ilex paraguariensis A. St.‐Hil.) for new therapeutic and nutraceutical interventions: A review of patents issued in the last 20 years (2000–2020)21
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Gastrodia elata Blume water extract modulates neurotransmitters and alters the gut microbiota in a mild social defeat stress‐induced depression mouse model21
Green tea extract ameliorates macrophage‐driven emphysematous lesions in chronic obstructive pulmonary disease induced by cigarette smoke condensate21
The therapeutic potential of typical plant‐derived compounds for the management of metabolic disorders21
Honokiol inhibits epithelial–mesenchymal transition and hepatic fibrosis via activation of Ecadherin/GSK3β/JNK and inhibition of AKT/ERK/p38/β‐catenin/21
The pharmacological effects of Berberine and its therapeutic potential in different diseases: Role of the phosphatidylinositol 3‐kinase/AKT signaling pathway21
Moringa oleiferaLam. as a potential plant for alleviation of the metabolic syndrome—A narrative review based on in vivo and clinical studies21
Eleutheroside B‐loaded poly (lactic‐co‐glycolic acid) nanoparticles protect against renal fibrosis via Smad3‐dependent mechanism21
Potential mechanism of oral baicalin treating psoriasis via suppressing Wnt signaling pathway and inhibiting Th17/IL‐17 axis by activating PPARγ21
Asiaticoside ameliorates DSS‐induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology20
Role of herbal medicine for prevention and treatment of migraine20
Myricetin reverses epithelial–endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR120
Salvianolic acid B alleviates autoimmunity in Treg‐deficient mice via inhibiting IL2‐STAT5 signaling20
An extensive review on phytochemistry and pharmacological activities of Indian medicinal plantCelastrus paniculatusWilld20
Agrimoniin is a dual inhibitor of AKT and ERK pathways that inhibit pancreatic cancer cell proliferation20
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Comparing the activity of propolis‐loaded nanoparticles or hydroethanolic extract on cytokine production by peripheral blood mononuclear cells20
A Comprehensive Review of Biologically Active Natural Products on Human Papillomavirus (HPV) at a Glance20
Identification of Cannabidiolic and Cannabigerolic Acids as MTDL AChE, BuChE, and BACE‐1 Inhibitors Against Alzheimer's Disease by In Silico, In Vitro, and In Vivo Stu20
Icariin, a phytoestrogen, exerts rapid estrogenic actions through crosstalk of estrogen receptors in osteoblasts20
Aqueous extract ofCeratonia siliquaL. leaves elicits antioxidant, anti‐inflammatory, andAChEinhibiting effects in amyloid‐β42‐induced cognitive deficit mice: Role ofα7‐nAChR19
Proteomic and metabolomic approaches elucidate the molecular mechanism of emodin against neuropathic pain through modulating the gamma‐aminobutyric acid (GABA)‐ergic pathway and PI3K19
Quercetin as a cancer chemopreventive or chemotherapeutic agent: Where we stand19
Alpinetin alleviates osteoporosis by promoting osteogenic differentiation in BMSCs by triggering autophagy via PKA/mTOR/ULK1 signaling19
The effects of Capsicum annuum supplementation on lipid profiles in adults with metabolic syndrome and related disorders: A systematic review and meta‐analysis of randomized controlled trials19
Fisetin attenuates doxorubicin‐induced cardiotoxicity by inhibiting the insulin‐like growth factor II receptor apoptotic pathway through estrogen receptor‐α/‐β activation19
Curcumin: A Potential Detoxifier Against Chemical and Natural Toxicants19
Neurological recovery and neurogenesis by curcumin sustained‐release system cross‐linked with an acellular spinal cord scaffold in rat spinal cord injury: TargetingNLRP3inflammasome pathway19
Ginger polysaccharide promotes myeloid‐derived suppressor cell apoptosis by regulating lipid metabolism19
Kaempferol's potential effects againstSARS‐CoV‐2 andCOVID‐19‐associated cancer progression and chemo‐resistance19
Triptolide promotes the apoptosis and attenuates the inflammation of fibroblast‐like synoviocytes in rheumatoid arthritis by down‐regulating lncRNA ENST0000061928219
Effect of rosemary leaf powder with weight loss diet on lipid profile, glycemic status, and liver enzymes in patients with nonalcoholic fatty liver disease: A randomized, double‐blind clinical trial19
Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway19
Contribution of traditional Chinese medicine combined with conventional western medicine treatment for the novel coronavirus disease (COVID‐19), current evidence with systematic review and 19
Current therapeutic targets and multifaceted physiological impacts of caffeine18
Tenuifolin ameliorates chronic restraint stress‐induced cognitive impairment in C57BL/6J mice18
Targeting autophagy and neuroinflammation pathways with plant‐derived natural compounds as potential antidepressant agents18
The effect of saffron supplementation on glycemic parameters: An overview of systematic reviews18
A critical review on clinical evidence of the efficacy of lavender in sleep disorders18
A randomized, double‐blind, placebo‐controlled, clinical trial to evaluate the benefits of Nigella sativa seeds oil in reducing cardiovascular risks in hyperten18
Curcumin and its anti‐colorectal cancer potential: From mechanisms of action to autophagy18
Crosstalk between traditional Chinese medicine‐derived polysaccharides and the gut microbiota: A new perspective to understand traditional Chinese medicine18
Quercetin and its derivates as antiviral potentials: A comprehensive review18
Propolis as an adjunctive therapy for treatment of uncomplicated cystitis in women: A randomized double‐blind placebo‐controlled trial18
Hesperidin reduces systolic blood pressure in diabetic patients and has no effect on blood pressure in healthy individuals: A systematic review and meta‐analysis18
Anti‐inflammatory effect of dictamnine on allergic rhinitis via suppression of the LYN kinase‐mediated molecular signaling pathway during mast cell activation18
Cryptotanshinone alleviates radiation‐induced lung fibrosis via modulation of gut microbiota and bile acid metabolism18
In vitro characterization of iridoid and phenylethanoid glycosides from Cistanche phelypaea for nutraceutical and pharmacological applications18
Juglone promotes antitumor activity against prostate cancer via suppressing glycolysis and oxidative phosphorylation18
Traditional Chinese medicine for gastric cancer: An evidence mapping17
Echinocystic acid prevents obesity and fatty liver via interacting withFABP117
Anthraquinone laxatives use and colorectal cancer: A systematic review and meta‐analysis of observational studies17
Therapeutic and prophylactic effect of flavonoids inpost‐COVID‐19 therapy17
Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15‐lipoxygenase17
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