OOIR: Observatory of International Research

Papers

(The H4-Index of Phytotherapy Research is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Autophagy inhibition enhances anti‐pituitary adenoma effect of tetrandrine	269
Curculigoside rescues hippocampal synaptic deficits elicited by PTSD through activating cAMP‐PKA signaling	244
Evaluation of the effect of Lepidium meyenii Walpers in infertile patients: A randomized, double‐blind, placebo‐controlled trial	147
Effects of different natural products in patients with non‐alcoholic fatty liver disease—A network meta‐analysis of randomized controlled trials	134
Efficacy of frankincense‐based herbal product in urinary incontinence: A randomized, double‐blind, placebo‐ and active‐controlled clinical trial	125
Cover Image	109
Dietary plants for oral cancer prevention and therapy: A review of preclinical and clinical studies	108
Morin attenuates osteoclast formation and function by suppressing the NF‐κB, MAPK and calcium signalling pathways	96
Pharmacovigilance of unlicensed cannabidiol in European countries	91
Safety assessment and adverse drug reaction reporting of tea tree oil (Melaleuca aetheroleum)	91
Phytoncides could potentially inhibit the spike protein of SARS‐CoV‐2 variants	89
Astragaloside IV Alleviates Acute Hepatic Injury by Regulating Macrophage Polarization and Pyroptosis via Activation of the AMPK/SIRT1 Signaling Pathway	85
Preclinical studies of the antitumor effect of curcumin‐loaded polymeric nanocapsules: A systematic review and meta‐analysis	83
Maltol mitigates cisplatin‐evoked cardiotoxicity via inhibiting the PI3K/Akt signaling pathway in rodents in vivo and in vitro	83
Co‐administration of sub‐effective doses of the constituents of Crocus sativus L. crocins with those of the antipsychotics clozapine and risperidone counteract memory deficits caused by blockad	82
RETRACTION: Epigallocatechin‐3‐Gallate Enhances Differentiation of Acute Promyelocytic Leukemia Cells via Inhibition of PML‐RARα and HDAC1	82
Antiplatelet effect of ginkgo diterpene lactone meglumine injection in acute ischemic stroke: A randomized, double‐blind, placebo‐controlled clinical trial	81
Licarin A, a neolignan isolated from Nectandra oppositifolia Nees & Mart. (Lauraceae), exhibited moderate preclinical efficacy against Schistosoma mansoni infection	80
Xanthohumol Regulates Mitophagy in Osteosarcoma Cells via AMPK‐ULK1‐FUNDC1 Signaling Pathway	78
Curcumin as a therapeutic agent in cancer therapy: Focusing on its modulatory effects on circularRNAs	78
Natural compounds as obesity pharmacotherapies	73
The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double‐blind, controlled trial	72
The effect of propolis supplementation on cardiovascular risk factors in women with rheumatoid arthritis: A double‐blind, placebo, controlled randomized clinical trial	69
Schisandra B, a representative lignan from Schisandra chinensis, improves cisplatin‐induced toxicity: An in vitro study	68
Bryodulcosigenin attenuates bleomycin‐induced pulmonary fibrosis via inhibiting AMPK‐mediated mesenchymal epithelial transition and oxidative stress	68

Phase III randomized clinical trial of BV‐4051, an Ayurvedic polyherbal formulation in moderate SARS‐CoV‐2 infections and its impact on inflammatory biomarkers	65
The influence of propolis plus Hyoscyamus niger L. against COVID‐19: A phase II, multicenter, placebo‐controlled, randomized trial	62
Vegetable‐derived indole enhances the melanoma‐treating efficacy of chemotherapeutics	62
Ethanol extract of Pueraria lobata improve acute myocardial infarction in rats via regulating gut microbiota and bile acid metabolism	62
Phytochemicals targeting ferroptosis in cardiovascular diseases: Recent advances and therapeutic perspectives	61
Anti‐Warburg effect via generation of ROS and inhibition of PKM2/β‐catenin mediates apoptosis of lambertianic acid in prostate cancer cells	59
Ellagitannin Component Punicalin Ameliorates Cognitive Dysfunction, Oxidative Stress, and Neuroinflammation via the Inhibition of cGAS‐STING Signaling in the Brain of an Aging Mo	59
Effects of gypenoside L‐containingGynostemma pentaphyllumextract on fatigue and physical performance: A double‐blind, placebo‐controlled, randomized trial	57
Saponin monomers: Potential candidates for the treatment of type 2 diabetes mellitus and its complications	57
Polysaccharides (pectin, mucilage, and fructan inulin) and their fermented products: A critical analysis of their biochemical, gut interactions, and biological functions as antidiabetic agents	56
Polydatin as a therapeutic alternative for central nervous system disorders: A systematic review of animal studies	54
Effects of artichoke leaf extract supplementation or artichoke juice consumption on lipid profile: A systematic review and dose–response meta‐analysis of randomized controlled trials	53
Morus alba L. water extract changes gut microbiota and fecal metabolome in mice induced by high‐fat and high‐sucrose diet plus low‐dose streptozotocin	50
	48
Upregulation of key factors of viral entry of corona‐ and influenza viruses upon TLR3‐signaling in cells from the respiratory tract and clinical treatment options by 1,8‐Cineol	47
The alleviative effect of flavonol‐type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders	47
	47
Hyperoside prevents doxorubicin‐induced cardiotoxicity by inhibiting NOXs/ROS/NLRP3 inflammasome signaling pathway	46
Jatrorrhizine alleviates cytokine storm secondary lung injury via regulating CD39‐dominant purinergic braking and downstream NLRP3 inflammasome	46
Mechanisms and Potential of Antitumor Therapy With Natural Products Regulating Non‐Coding RNAs	45
Bavachinin selectively modulates PPAR γ and maintains bone homeostasis in Type 2 Diabetes	45
Brazilian red propolis exerts a cytotoxic action against prostate cancer cells and upregulates human monocyte functions	45
Exploring the therapeutic implications of natural compounds modulating apoptosis in vascular dementia	45