Oncogene

Papers
(The TQCC of Oncogene is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Identification of novel germline mutations in FUT7 and EXT1 linked with hereditary multiple exostoses183
SOX10 deficiency-mediated LAMB3 upregulation determines the invasiveness of MAPKi-resistant melanoma153
Correction: Regulation of cancer stem cell activity by thyroid hormone receptor β149
Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells134
Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts133
Deciphering glioma epitranscriptome: focus on RNA modifications129
USP5 deubiquitinates and stabilizes IMPDH2, to promote hepatocellular carcinoma progression109
Correction: S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia108
Correction to: Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential105
Structure and function of MuvB complexes104
SKAP2 suppresses inflammation-mediated tumorigenesis by regulating SHP-1 and SHP-2102
RBMS3-loss impedes TRIM21-induced ubiquitination of ANGPT2 in an RNA-independent manner and drives sorafenib resistance in hepatocellular carcinoma101
Correction: Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer93
A comprehensive analysis of LMO2 pathogenic regulatory profile during T-lineage development and leukemic transformation87
The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis86
Correction: Targeting the HIF-1α-IGFBP2 axis therapeutically reduces IGF1-AKT signaling and blocks the growth and metastasis of relapsed anaplastic Wilms tumor84
LIGHT enhanced bispecific antibody armed T-cells to treat immunotherapy resistant colon cancer81
AMPK-deficiency forces metformin-challenged cancer cells to switch from carbohydrate metabolism to ketogenesis to support energy metabolism80
SCD5-dependent inhibition of SPARC secretion hampers metastatic spreading and favors host immunity in a TNBC murine model80
Correction: SOX18 promotes gastric cancer metastasis through transactivating MCAM and CCL773
Retraction Note: CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells72
Gamma-glutamyltransferase 7 suppresses gastric cancer by cooperating with RAB7 to induce mitophagy71
A novel amplification gene PCI domain containing 2 (PCID2) promotes colorectal cancer through directly degrading a tumor suppressor promyelocytic leukemia (PML)70
Spatiotemporal view of malignant histogenesis and macroevolution via formation of polyploid giant cancer cells70
Trop-2, Na+/K+ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion69
Nup54-induced CARM1 nuclear importation promotes gastric cancer cell proliferation and tumorigenesis through transcriptional activation and methylation of Notch268
MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex66
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer65
Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks65
GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation63
Notch signaling regulates a metabolic switch through inhibiting PGC-1α and mitochondrial biogenesis in dedifferentiated liposarcoma63
MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells63
Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity62
Hypoxia induces chemoresistance to proteasome inhibitors through orchestrating deSUMOylation and ubiquitination of SRC-3 in multiple myeloma62
tRF-33-P4R8YP9LON4VDP inhibits gastric cancer progression via modulating STAT3 signaling pathway in an AGO2-dependent manner61
YTHDF2 is a potential target of AML1/ETO-HIF1α loop-mediated cell proliferation in t(8;21) AML61
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin60
METTL3-mediated N6-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF459
ALDH1A3 is the switch that determines the balance of ALDH+ and CD24−CD44+ cancer stem cells, EMT-MET, and glucose metabolism in breast cancer59
BTLA+CD200+ B cells dictate the divergent immune landscape and immunotherapeutic resistance in metastatic vs. primary pancreatic cancer58
Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma58
LncRNA XIST regulates breast cancer stem cells by activating proinflammatory IL-6/STAT3 signaling58
Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis56
ANKFN1 plays both protumorigenic and metastatic roles in hepatocellular carcinoma56
H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth56
Single-cell multiomics reveals a gene regulatory circuit driving leukemia cell differentiation55
Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis54
MASTL regulates EGFR signaling to impact pancreatic cancer progression54
CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of β-catenin54
Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF26353
The protection of UCK2 protein stability by GART maintains pyrimidine salvage synthesis for HCC growth under glucose limitation53
Crosstalk between endothelial progenitor cells and HCC through periostin/CCL2/CD36 supports formation of the pro-metastatic microenvironment in HCC52
Induction of IL6/STAT3-dependent TRAIL expression that contributes to the therapeutic efficacy of osimertinib in EGFR mutant NSCLC cells51
Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance51
STT3A-mediated viral N-glycosylation underlies the tumor selectivity of oncolytic virus M150
ST6Gal1 targets the ectodomain of ErbB2 in a site-specific manner and regulates gastric cancer cell sensitivity to trastuzumab48
CircKDM4B suppresses breast cancer progression via the miR-675/NEDD4L axis48
Alternative splicing in prostate cancer progression and therapeutic resistance47
The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival47
RB loss determines selective resistance and novel vulnerabilities in ER-positive breast cancer models47
PRSS23-eIF4E-c-Myc axis promotes gastric tumorigenesis and progression46
The platelet pannexin 1-IL-1β axis orchestrates pancreatic ductal adenocarcinoma invasion and metastasis46
Retraction Note: Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis46
CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-inducing phenotype46
RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP245
AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors45
Correction to: EphA2–YES1–ANXA2 pathway promotes gastric cancer progression and metastasis45
Application of machine learning to large in-vitro databases to identify cancer cell characteristics: telomerase reverse transcriptase (TERT) expression45
RNA-sequencing predicts a role of androgen receptor and aldehyde dehydrogenase 1A1 in osteosarcoma lung metastases45
Pancreatic ductal adenocarcinoma induces neural injury that promotes a transcriptomic and functional repair signature by peripheral neuroglia45
Correction: MZF1 mediates oncogene-induced senescence by promoting the transcription of p16INK4A44
Correction: Exosomal circCARM1 from spheroids reprograms cell metabolism by regulating PFKFB2 in breast cancer43
Ornithine decarboxylase (ODC1) gene variant (rs2302615) is associated with gastric cancer independently of Helicobacter pylori CagA serostatus43
AGO4 suppresses tumor growth by modulating autophagy and apoptosis via enhancing TRIM21-mediated ubiquitination of GRP78 in a p53-independent manner43
Correction: Editorial Expression of Concern: Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer43
Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction43
Correction: MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP143
Editorial Expression of Concern: Role of BRCA1 in heat shock response42
Correction to: Cervical squamous cell carcinoma-secreted exosomal miR-221-3p promotes lymphangiogenesis and lymphatic metastasis by targeting VASH142
Correction to: Ionizing radiation-induced NF-κB activation requires PARP-1 function to confer radioresistance42
Recent insights into the causes and consequences of chromosome mis-segregation41
Revealing the tumor suppressive sequence within KL1 domain of the hormone Klotho41
Delactylase effects of SIRT1 on a positive feedback loop involving the H19-glycolysis-histone lactylation in gastric cancer41
Transferrin receptor 1 promotes the fibroblast growth factor receptor-mediated oncogenic potential of diffused-type gastric cancer40
FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis40
The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-Raf and MAPK signaling cascade40
ROS production by mitochondria: function or dysfunction?40
Decitabine enhances targeting of AML cells by NY-ESO-1-specific TCR-T cells and promotes the maintenance of effector function and the memory phenotype39
RB1 loss in castration-resistant prostate cancer confers vulnerability to LSD1 inhibition39
The influence of endothelial metabolic reprogramming on the tumor microenvironment39
Functional inhibition of cancer stemness-related protein DPP4 rescues tyrosine kinase inhibitor resistance in renal cell carcinoma39
Stabilization of MOF (KAT8) by USP10 promotes esophageal squamous cell carcinoma proliferation and metastasis through epigenetic activation of ANXA2/Wnt signaling39
Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma39
Inactivation of EGLN3 hydroxylase facilitates Erk3 degradation via autophagy and impedes lung cancer growth38
C4orf19 inhibits colorectal cancer cell proliferation by competitively binding to Keap1 with TRIM25 via the USP17/Elk-1/CDK6 axis38
Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis38
SIRT7: a novel molecular target for personalized cancer treatment?38
METTL3 promotes cellular senescence of colorectal cancer via modulation of CDKN2B transcription and mRNA stability37
OLFM4 deficiency delays the progression of colitis to colorectal cancer by abrogating PMN-MDSCs recruitment37
PIM1 drives lipid droplet accumulation to promote proliferation and survival in prostate cancer37
SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity37
Therapeutic targeting the oncogenic driver EWSR1::FLI1 in Ewing sarcoma through inhibition of the FACT complex37
Cell surface GRP78 and Dermcidin cooperate to regulate breast cancer cell migration through Wnt signaling37
YBX1 promotes 5-Fluorouracil resistance in gastric cancer via m5C-dependent ATG9A mRNA stabilization through autophagy37
Cyclin E1 overexpression sensitizes ovarian cancer cells to WEE1 and PLK1 inhibition36
Ac4C modification of lncRNA SIMALR promotes nasopharyngeal carcinoma progression through activating eEF1A2 to facilitate ITGB4/ITGA6 translation36
The kinesin KIF20A promotes progression to castration-resistant prostate cancer through autocrine activation of the androgen receptor36
Tumor innervation is triggered by endoplasmic reticulum stress36
Phosphorylation of USP27X by PIM2 promotes glycolysis and breast cancer progression via deubiquitylation of MYC36
Functional screening reveals HORMAD1-driven gene dependencies associated with translesion synthesis and replication stress tolerance36
E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer36
Matriptase-2/NR4A3 axis switches TGF-β action toward suppression of prostate cancer cell invasion, tumor growth, and metastasis35
Correction: NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment35
Calcineurin inactivation inhibits pyruvate dehydrogenase complex activity and induces the Warburg effect35
Engineering prostate cancer in vitro: what does it take?35
Correction: Targeting MERTK on tumour cells and macrophages: a potential intervention for sporadic and NF2-related meningioma and schwannoma tumours35
Correction to: Long non-coding RNA KRT19P3 suppresses proliferation and metastasis through COPS7A-mediated NF-κB pathway in gastric cancer35
Oncogenic SNORD12B activates the AKT-mTOR-4EBP1 signaling in esophageal squamous cell carcinoma via nucleus partitioning of PP-1α35
Correction: PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production35
The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells35
Mesenchymal stromal cells confer breast cancer doxorubicin resistance by producing hyaluronan34
Tumor-mesothelium HOXA11-PDGF BB/TGF β1-miR-181a-5p-Egr1 feedforward amplifier circuity propels mesothelial fibrosis and peritoneal metastasis of gastric cancer34
MicroRNAs: circulating biomarkers for the early detection of imperceptible cancers via biosensor and machine-learning advances34
Correction: ROR1-targeting switchable CAR-T cells for cancer therapy34
OTUB1 suppresses Hippo signaling via modulating YAP protein in gastric cancer34
Tumor cell-derived ANGPTL2 promotes β-catenin-driven intestinal tumorigenesis34
Enhanced anti-cancer efficacy of arginine deaminase expressed by tumor-seeking Salmonella Gallinarum34
Identification of mutations that cooperate with defects in B cell transcription factors to initiate leukemia34
Feedback activation of EGFR/wild-type RAS signaling axis limits KRASG12D inhibitor efficacy in KRASG12D-mutated colorectal cancer34
Inactivation of kindlin-3 increases human melanoma aggressiveness through the collagen-activated tyrosine kinase receptor DDR133
Retraction Note: Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor33
The role of miR-92b-3p in notch signaling and monitoring of oral squamous cell carcinoma33
Muc16 depletion diminishes KRAS-induced tumorigenesis and metastasis by altering tumor microenvironment factors in pancreatic ductal adenocarcinoma33
The immunological role of ADAMs in the field of gastroenterological chronic inflammatory diseases and cancers: a review33
O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation33
Correction: Transactivation of human endogenous retrovirus K (HERV-K) by KSHV promotes Kaposi’s sarcoma development33
Correction: Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma33
Correction to: Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA5533
Correction: Loss-of-function mutations of SOX17 lead to YAP/TEAD activation-dependent malignant transformation in endometrial cancer33
Retraction Note: Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1α levels contribute to emergence of an aggressive phenotype in prostat32
Correction: LncRNA BCYRN1 inhibits glioma tumorigenesis by competitively binding with miR-619-5p to regulate CUEDC2 expression and the PTEN/AKT/p21 pathway32
Correction: IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma32
miR-22 promotes stem cell traits via activating Wnt/β-catenin signaling in cutaneous squamous cell carcinoma32
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations32
Editorial Expression of Concern: Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene32
Thioredoxin reductase is a major regulator of metabolism in leukemia cells32
Molecular explorations of cancer biology and therapeutics at PDB-10132
Celastrol recruits UBE3A to recognize and degrade the DNA binding domain of steroid receptors31
Shallow whole genome re-sequencing to precisely predict benefit from PARP inhibitor31
Correction to: Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation31
Single-cell landscape of undifferentiated pleomorphic sarcoma31
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer31
Zinc ions activate AKT and promote prostate cancer cell proliferation via disrupting AKT intramolecular interaction31
Phosphorylation of FOXK2 at Thr13 and Ser30 by PDK2 sustains glycolysis through a positive feedback manner in ovarian cancer31
A proof of concept for targeting the PrPC - Amyloid β peptide interaction in basal prostate cancer and mesenchymal colon cancer31
Lysine metabolism is a novel metabolic tumor suppressor pathway in breast cancer31
Correction: The ELF3-regulated lncRNA UBE2CP3 is over-stabilized by RNA–RNA interactions and drives gastric cancer metastasis via miR-138-5p/ITGA2 axis31
ARHGAP–RhoA signaling provokes homotypic adhesion-triggered cell death of metastasized diffuse-type gastric cancer31
Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy30
Targeting SLP2-mediated lipid metabolism reprograming restricts proliferation and metastasis of hepatocellular carcinoma and promotes sensitivity to Lenvatinib30
HJURP is recruited to double-strand break sites and facilitates DNA repair by promoting chromatin reorganization30
sEV-mediated intercellular transformation from MGAT4AHigh to MGAT4ALow tumor cells via the HOTAIRM1/miR-196b-5p axis promotes apoptosis resistance in CTCL30
circIPO7 dissociates caprin-1 from ribosomes and inhibits gastric cancer cell proliferation by suppressing EGFR and mTOR30
Correction: Combination strategies with PARP inhibitors in BRCA-mutated triple-negative breast cancer: overcoming resistance mechanisms30
Clustering single-cell RNA sequencing data via iterative smoothing and self-supervised discriminative embedding30
Selective inhibition of CDK9 in triple negative breast cancer30
HOTAIR/Sp1/miR-199a critically regulates cancer stemness and malignant progression of cutaneous squamous cell carcinoma30
LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination30
PPP2R1A mutations cause ATR inhibitor sensitivity in ovarian clear cell carcinoma29
The strategy and clinical relevance of in vitro models of MAP resistance in osteosarcoma: a systematic review29
CircVPS8 promotes the malignant phenotype and inhibits ferroptosis of glioma stem cells by acting as a scaffold for MKRN1, SOX15 and HNF4A29
Long non-coding RNA-MIR181A1HG acts as an oncogene and contributes to invasion and metastasis in gastric cancer29
PPDPF promotes lung adenocarcinoma progression via inhibiting apoptosis and NK cell-mediated cytotoxicity through STAT329
Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 129
AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer29
CBX3 accelerates the malignant progression of glioblastoma multiforme by stabilizing EGFR expression29
Chemerin enhances mesenchymal features of glioblastoma by establishing autocrine and paracrine networks in a CMKLR1-dependent manner29
The multifaceted role of EGLN family prolyl hydroxylases in cancer: going beyond HIF regulation29
Engineered targeting OIP5 sensitizes bladder cancer to chemotherapy resistance via TRIP12-PPP1CB-YBX1 axis29
The proteomic characterization of the peritumor microenvironment in human hepatocellular carcinoma29
Retraction Note: Aurora-A is a determinant of tamoxifen sensitivity through phosphorylation of ERα in breast cancer28
GSTO1 aggravates EGFR-TKIs resistance and tumor metastasis via deglutathionylation of NPM1 in lung adenocarcinoma28
Retraction Note: E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage28
Critical requirement of SOS1 RAS-GEF function for mitochondrial dynamics, metabolism, and redox homeostasis28
Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells28
WTAP-mediated m6A methylation of PHF19 facilitates cell cycle progression by remodeling the accessible chromatin landscape in t(8;21) AML28
Loss of deubiquitylase USP2 triggers development of glioblastoma via TGF-β signaling28
Alcohol-driven metabolic reprogramming promotes development of RORγt-deficient thymic lymphoma28
Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers28
Irreversible JNK blockade overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer28
JAK2/ULK1 axis promotes cervical cancer progression by autophagy induction and SRPK1 phosphorylation28
Neuropilin-2 promotes lineage plasticity and progression to neuroendocrine prostate cancer28
Correction: Enhanced YB1/EphA2 axis signaling promotes acquired resistance to sunitinib and metastatic potential in renal cell carcinoma28
Editorial Expression of Concern: Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4–miR-18a pathway in cervical cancer28
Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGFβ signaling28
RETRACTED ARTICLE: Targeting HIF-1α/NOTCH1 pathway eliminates CD44+ cancer stem-like cell phenotypes, malignancy, and resistance to therapy in head and neck squamous cell carcinoma28
PP2A-B55: substrates and regulators in the control of cellular functions27
The landscape and biological relevance of aberrant alternative splicing events in esophageal squamous cell carcinoma27
RNF126-mediated ubiquitination of FSP1 affects its subcellular localization and ferroptosis27
VprBP/DCAF1 regulates p53 function and stability through site-specific phosphorylation27
CD73 induces GM-CSF/MDSC-mediated suppression of T cells to accelerate pancreatic cancer pathogenesis27
ScRNA-seq of gastric cancer tissues reveals differences in the immune microenvironment of primary tumors and metastases27
Origin and Evolution of RAS Membrane Targeting27
Integrative metabolomic characterization identifies plasma metabolomic signature in the diagnosis of papillary thyroid cancer27
Ubiquitin and ubiquitin-like proteins in HPV-driven carcinogenesis27
Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 627
The role of α-klotho in human cancer: molecular and clinical aspects27
Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation26
PELO facilitates PLK1-induced the ubiquitination and degradation of Smad4 and promotes the progression of prostate cancer26
Protein disulfide isomerase-enriched extracellular vesicles from bladder cancer cells support tumor survival and malignant transformation in the bladder26
DCision-making in tumors governs T cell anti-tumor immunity26
Repurposed pizotifen malate targeting NRF2 exhibits anti-tumor activity through inducing ferroptosis in esophageal squamous cell carcinoma26
TTPAL promotes gastric tumorigenesis by directly targeting NNMT to activate PI3K/AKT signaling26
GNAO1 overexpression promotes neural differentiation of glioma stem-like cells and reduces tumorigenicity through TRIM21/CREB/HES1 axis26
Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge26
How artificial intelligence might disrupt diagnostics in hematology in the near future26
DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth26
A novel lncRNA MTAR1 promotes cancer development through IGF2BPs mediated post-transcriptional regulation of c-MYC26
Single-cell RNA-seq recognized the initiator of epithelial ovarian cancer recurrence26
Appearance of tuft cells during prostate cancer progression26
A novel integrated approach to predicting cancer immunotherapy efficacy26
M6A-mediated-upregulation of lncRNA BLACAT3 promotes bladder cancer angiogenesis and hematogenous metastasis through YBX3 nuclear shuttling and enhancing NCF2 transcription26
FOXM1 is required for small cell lung cancer tumorigenesis and associated with poor clinical prognosis26
Retraction Note: MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer25
GDP-mannose 4,6-dehydratase is a key driver of MYCN-amplified neuroblastoma core fucosylation and tumorigenesis25
Amyloid-like p53 as prognostic biomarker in serous ovarian cancer—a study of the OVCAD consortium25
HMGB1/SET/HAT1 complex-mediated SASH1 repression drives glycolysis and metastasis in lung adenocarcinoma25
Correction: Alpelisib and fulvestrant in PIK3CA-mutated hormone receptor-positive HER2-negative advanced breast cancer included in the French early access program25
Epigenetics behind tumor immunology: a mini review25
Correction: Novel targeted mtLivin nanoparticles treatment for disseminated diffuse large B-cell lymphoma25
Targeting RBM39 suppresses tumor growth and sensitizes osteosarcoma cells to cisplatin25
SMARCE1 promotes neuroblastoma tumorigenesis through assisting MYCN-mediated transcriptional activation25
p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs25
Fulvestrant and everolimus efficacy after CDK4/6 inhibitor: a prospective study with circulating tumor DNA analysis25
Correction: TSPAN6 is a suppressor of Ras-driven cancer25
Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer25
Enhancer rewiring in tumors: an opportunity for therapeutic intervention25
Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer24
IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma24
Cancer-associated fibroblasts promote EGFR-TKI resistance via the CTHRC1/glycolysis/H3K18la positive feedback loop24
RUVBL1 promotes enzalutamide resistance of prostate tumors through the PLXNA1-CRAF-MAPK pathway24
Nuclear translocation of Gasdermin D sensitizes colorectal cancer to chemotherapy in a pyroptosis-independent manner24
JMJD6 in tumor-associated macrophage regulates macrophage polarization and cancer progression via STAT3/IL-10 axis24
β-Catenin-CCL2 feedback loop mediates crosstalk between cancer cells and macrophages that regulates breast cancer stem cells24
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma24
Exosomal circSPIRE1 mediates glycosylation of E-cadherin to suppress metastasis of renal cell carcinoma24
Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment24
Spatial collagen stiffening promotes collective breast cancer cell invasion by reinforcing extracellular matrix alignment24
Subsets of cancer cells expressing CX3CR1 are endowed with metastasis-initiating properties and resistance to chemotherapy24
M7G modification of FTH1 and pri-miR-26a regulates ferroptosis and chemotherapy resistance in osteosarcoma24
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