Oncogene

Papers
(The TQCC of Oncogene is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Identification of novel germline mutations in FUT7 and EXT1 linked with hereditary multiple exostoses229
SOX10 deficiency-mediated LAMB3 upregulation determines the invasiveness of MAPKi-resistant melanoma193
Correction: Regulation of cancer stem cell activity by thyroid hormone receptor β155
Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts147
Correction: S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia98
Correction to: Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential97
Correction: Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer96
Correction: Targeting the HIF-1α-IGFBP2 axis therapeutically reduces IGF1-AKT signaling and blocks the growth and metastasis of relapsed anaplastic Wilms tumor95
Retraction Note: CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells90
Structure and function of MuvB complexes89
GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation88
USP5 deubiquitinates and stabilizes IMPDH2, to promote hepatocellular carcinoma progression86
Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity83
A novel amplification gene PCI domain containing 2 (PCID2) promotes colorectal cancer through directly degrading a tumor suppressor promyelocytic leukemia (PML)83
Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks82
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin75
ANKFN1 plays both protumorigenic and metastatic roles in hepatocellular carcinoma74
A comprehensive analysis of LMO2 pathogenic regulatory profile during T-lineage development and leukemic transformation71
Hypoxia induces chemoresistance to proteasome inhibitors through orchestrating deSUMOylation and ubiquitination of SRC-3 in multiple myeloma70
MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex68
Correction: DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity68
BTLA+CD200+ B cells dictate the divergent immune landscape and immunotherapeutic resistance in metastatic vs. primary pancreatic cancer68
Gamma-glutamyltransferase 7 suppresses gastric cancer by cooperating with RAB7 to induce mitophagy68
The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis68
RBMS3-loss impedes TRIM21-induced ubiquitination of ANGPT2 in an RNA-independent manner and drives sorafenib resistance in hepatocellular carcinoma67
LIGHT enhanced bispecific antibody armed T-cells to treat immunotherapy resistant colon cancer67
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer66
Retraction Note: Fermitin family member 2 promotes melanoma progression by enhancing the binding of p-α-Pix to Rac1 to activate the MAPK pathway65
Notch signaling regulates a metabolic switch through inhibiting PGC-1α and mitochondrial biogenesis in dedifferentiated liposarcoma65
Trop-2, Na+/K+ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion63
RETRACTED ARTICLE: Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma62
Vimentin intermediate filaments orchestrate DNA nonhomologous end joining repair and lipolysis after DNA damage62
Deciphering glioma epitranscriptome: focus on RNA modifications61
H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth57
Increased antiandrogen enzalutamide sensitivity via altering prostate cancer stem cell traits through modulating the androgen receptor-mediated CDR1/circCDR1-AS/miR-1290/BMP4 signaling56
METTL3-mediated N6-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF455
Spatiotemporal view of malignant histogenesis and macroevolution via formation of polyploid giant cancer cells55
LncRNA XIST regulates breast cancer stem cells by activating proinflammatory IL-6/STAT3 signaling55
Nup54-induced CARM1 nuclear importation promotes gastric cancer cell proliferation and tumorigenesis through transcriptional activation and methylation of Notch254
ALDH1A3 is the switch that determines the balance of ALDH+ and CD24−CD44+ cancer stem cells, EMT-MET, and glucose metabolism in breast cancer54
Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells54
tRF-33-P4R8YP9LON4VDP inhibits gastric cancer progression via modulating STAT3 signaling pathway in an AGO2-dependent manner53
SKAP2 suppresses inflammation-mediated tumorigenesis by regulating SHP-1 and SHP-250
Single-cell multiomics reveals a gene regulatory circuit driving leukemia cell differentiation49
Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis49
STT3A-mediated viral N-glycosylation underlies the tumor selectivity of oncolytic virus M149
SCD5-dependent inhibition of SPARC secretion hampers metastatic spreading and favors host immunity in a TNBC murine model49
Crosstalk between endothelial progenitor cells and HCC through periostin/CCL2/CD36 supports formation of the pro-metastatic microenvironment in HCC48
Alternative splicing in prostate cancer progression and therapeutic resistance48
Correction: HMGB1 correlates with angiogenesis and poor prognosis of perihilar cholangiocarcinoma via elevating VEGFR2 of vessel endothelium48
Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF26348
RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP247
Delactylase effects of SIRT1 on a positive feedback loop involving the H19-glycolysis-histone lactylation in gastric cancer47
AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors47
RB loss determines selective resistance and novel vulnerabilities in ER-positive breast cancer models47
The platelet pannexin 1-IL-1β axis orchestrates pancreatic ductal adenocarcinoma invasion and metastasis47
Correction: Editorial Expression of Concern: Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer46
Correction to: EphA2–YES1–ANXA2 pathway promotes gastric cancer progression and metastasis46
Correction: Exosomal circCARM1 from spheroids reprograms cell metabolism by regulating PFKFB2 in breast cancer46
RNA-sequencing predicts a role of androgen receptor and aldehyde dehydrogenase 1A1 in osteosarcoma lung metastases46
Correction: MZF1 mediates oncogene-induced senescence by promoting the transcription of p16INK4A46
Correction to: Ionizing radiation-induced NF-κB activation requires PARP-1 function to confer radioresistance45
Correction: MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP145
Recent insights into the causes and consequences of chromosome mis-segregation44
Editorial Expression of Concern: Role of BRCA1 in heat shock response44
CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of β-catenin44
The protection of UCK2 protein stability by GART maintains pyrimidine salvage synthesis for HCC growth under glucose limitation44
Correction to: Cervical squamous cell carcinoma-secreted exosomal miR-221-3p promotes lymphangiogenesis and lymphatic metastasis by targeting VASH144
Revealing the tumor suppressive sequence within KL1 domain of the hormone Klotho44
PABPN1-C5 axis promotes hepatocellular carcinoma progression via NF-κB activation43
The lncRNA ST18-AS1 suppresses pancreatic cancer progression by enhancing ST18 mRNA stability through anchoring FUS in the cytoplasm43
Correction: An FGFR-p53 developmental signaling axis drives salivary cancer progression43
Pancreatic ductal adenocarcinoma induces neural injury that promotes a transcriptomic and functional repair signature by peripheral neuroglia42
Transferrin receptor 1 promotes the fibroblast growth factor receptor-mediated oncogenic potential of diffused-type gastric cancer42
PRSS23-eIF4E-c-Myc axis promotes gastric tumorigenesis and progression42
Post-transcriptional control of gene expression by β-catenin: expanding the non-canonical ARMoury41
CircKDM4B suppresses breast cancer progression via the miR-675/NEDD4L axis41
The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival41
Retraction Note: Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis41
CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-inducing phenotype40
Membrane flexibility induced by BST2 contributes to radioresistance in glioblastoma40
Induction of IL6/STAT3-dependent TRAIL expression that contributes to the therapeutic efficacy of osimertinib in EGFR mutant NSCLC cells40
Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction40
ROS production by mitochondria: function or dysfunction?39
AGO4 suppresses tumor growth by modulating autophagy and apoptosis via enhancing TRIM21-mediated ubiquitination of GRP78 in a p53-independent manner39
Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis39
Tumor cell-derived ANGPTL2 promotes β-catenin-driven intestinal tumorigenesis38
Enhanced anti-cancer efficacy of arginine deaminase expressed by tumor-seeking Salmonella Gallinarum38
Tumor innervation is triggered by endoplasmic reticulum stress38
E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer38
Decitabine enhances targeting of AML cells by NY-ESO-1-specific TCR-T cells and promotes the maintenance of effector function and the memory phenotype38
Correction to: Long non-coding RNA KRT19P3 suppresses proliferation and metastasis through COPS7A-mediated NF-κB pathway in gastric cancer37
The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-Raf and MAPK signaling cascade37
Functional screening reveals HORMAD1-driven gene dependencies associated with translesion synthesis and replication stress tolerance37
Correction: PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production37
Therapeutic targeting the oncogenic driver EWSR1::FLI1 in Ewing sarcoma through inhibition of the FACT complex37
Cyclin E1 overexpression sensitizes ovarian cancer cells to WEE1 and PLK1 inhibition36
Correction: Targeting MERTK on tumour cells and macrophages: a potential intervention for sporadic and NF2-related meningioma and schwannoma tumours36
RB1 loss in castration-resistant prostate cancer confers vulnerability to LSD1 inhibition36
Engineering prostate cancer in vitro: what does it take?36
Correction: ROR1-targeting switchable CAR-T cells for cancer therapy36
Matriptase-2/NR4A3 axis switches TGF-β action toward suppression of prostate cancer cell invasion, tumor growth, and metastasis36
Correction: NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment36
SIRT7: a novel molecular target for personalized cancer treatment?36
YBX1 promotes 5-Fluorouracil resistance in gastric cancer via m5C-dependent ATG9A mRNA stabilization through autophagy35
C4orf19 inhibits colorectal cancer cell proliferation by competitively binding to Keap1 with TRIM25 via the USP17/Elk-1/CDK6 axis35
Calcineurin inactivation inhibits pyruvate dehydrogenase complex activity and induces the Warburg effect35
Ac4C modification of lncRNA SIMALR promotes nasopharyngeal carcinoma progression through activating eEF1A2 to facilitate ITGB4/ITGA6 translation35
Muc16 depletion diminishes KRAS-induced tumorigenesis and metastasis by altering tumor microenvironment factors in pancreatic ductal adenocarcinoma35
BRD4 regulates PAI-1 expression in tumor-associated macrophages to drive chemoresistance in colorectal cancer35
The influence of endothelial metabolic reprogramming on the tumor microenvironment34
Stabilization of MOF (KAT8) by USP10 promotes esophageal squamous cell carcinoma proliferation and metastasis through epigenetic activation of ANXA2/Wnt signaling34
Feedback activation of EGFR/wild-type RAS signaling axis limits KRASG12D inhibitor efficacy in KRASG12D-mutated colorectal cancer34
Inactivation of EGLN3 hydroxylase facilitates Erk3 degradation via autophagy and impedes lung cancer growth34
Phosphorylation of USP27X by PIM2 promotes glycolysis and breast cancer progression via deubiquitylation of MYC34
OLFM4 deficiency delays the progression of colitis to colorectal cancer by abrogating PMN-MDSCs recruitment34
Correction: Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E34
METTL3 promotes cellular senescence of colorectal cancer via modulation of CDKN2B transcription and mRNA stability33
SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity33
PIM1 drives lipid droplet accumulation to promote proliferation and survival in prostate cancer33
Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis33
Decoding the adaptive survival mechanisms of breast cancer dormancy33
Mesenchymal stromal cells confer breast cancer doxorubicin resistance by producing hyaluronan33
OTUB1 suppresses Hippo signaling via modulating YAP protein in gastric cancer33
The kinesin KIF20A promotes progression to castration-resistant prostate cancer through autocrine activation of the androgen receptor33
Identification of mutations that cooperate with defects in B cell transcription factors to initiate leukemia33
MicroRNAs: circulating biomarkers for the early detection of imperceptible cancers via biosensor and machine-learning advances32
Tumor-mesothelium HOXA11-PDGF BB/TGF β1-miR-181a-5p-Egr1 feedforward amplifier circuity propels mesothelial fibrosis and peritoneal metastasis of gastric cancer32
Correction to: Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA5532
Correction: Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma32
Retraction Note: Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor31
Correction: IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma31
Correction: Transactivation of human endogenous retrovirus K (HERV-K) by KSHV promotes Kaposi’s sarcoma development31
Retraction Note: Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1α levels contribute to emergence of an aggressive phenotype in prostat31
Lysine metabolism is a novel metabolic tumor suppressor pathway in breast cancer31
Correction: Loss-of-function mutations of SOX17 lead to YAP/TEAD activation-dependent malignant transformation in endometrial cancer31
Correction: The ELF3-regulated lncRNA UBE2CP3 is over-stabilized by RNA–RNA interactions and drives gastric cancer metastasis via miR-138-5p/ITGA2 axis31
Molecular explorations of cancer biology and therapeutics at PDB-10131
Phosphorylation of FOXK2 at Thr13 and Ser30 by PDK2 sustains glycolysis through a positive feedback manner in ovarian cancer30
Shallow whole genome re-sequencing to precisely predict benefit from PARP inhibitor30
Zinc ions activate AKT and promote prostate cancer cell proliferation via disrupting AKT intramolecular interaction30
Celastrol recruits UBE3A to recognize and degrade the DNA binding domain of steroid receptors30
Single-cell landscape of undifferentiated pleomorphic sarcoma30
Correction to: Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation30
Editorial Expression of Concern: Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress29
ARHGAP–RhoA signaling provokes homotypic adhesion-triggered cell death of metastasized diffuse-type gastric cancer29
circIPO7 dissociates caprin-1 from ribosomes and inhibits gastric cancer cell proliferation by suppressing EGFR and mTOR29
The role of miR-92b-3p in notch signaling and monitoring of oral squamous cell carcinoma29
HJURP is recruited to double-strand break sites and facilitates DNA repair by promoting chromatin reorganization29
CircVPS8 promotes the malignant phenotype and inhibits ferroptosis of glioma stem cells by acting as a scaffold for MKRN1, SOX15 and HNF4A29
Editorial Expression of Concern: Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene29
Correction: Combination strategies with PARP inhibitors in BRCA-mutated triple-negative breast cancer: overcoming resistance mechanisms29
A multi-faceted discovery strategy identifies functional antibodies binding to cysteine-rich domain 1 of hDKK1 for cancer immunotherapy via Wnt non-canonical pathway29
sEV-mediated intercellular transformation from MGAT4AHigh to MGAT4ALow tumor cells via the HOTAIRM1/miR-196b-5p axis promotes apoptosis resistance in CTCL29
Targeting SLP2-mediated lipid metabolism reprograming restricts proliferation and metastasis of hepatocellular carcinoma and promotes sensitivity to Lenvatinib28
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations28
KDM1A-driven RNF81 downregulation promotes gastric cancer progression via KLF4 destabilization28
CBX3 accelerates the malignant progression of glioblastoma multiforme by stabilizing EGFR expression28
Long non-coding RNA-MIR181A1HG acts as an oncogene and contributes to invasion and metastasis in gastric cancer28
PPDPF promotes lung adenocarcinoma progression via inhibiting apoptosis and NK cell-mediated cytotoxicity through STAT328
The proteomic characterization of the peritumor microenvironment in human hepatocellular carcinoma28
O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation28
Clustering single-cell RNA sequencing data via iterative smoothing and self-supervised discriminative embedding28
The immunological role of ADAMs in the field of gastroenterological chronic inflammatory diseases and cancers: a review28
The multifaceted role of EGLN family prolyl hydroxylases in cancer: going beyond HIF regulation28
Chemerin enhances mesenchymal features of glioblastoma by establishing autocrine and paracrine networks in a CMKLR1-dependent manner28
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer28
Inactivation of kindlin-3 increases human melanoma aggressiveness through the collagen-activated tyrosine kinase receptor DDR127
The strategy and clinical relevance of in vitro models of MAP resistance in osteosarcoma: a systematic review27
Engineered targeting OIP5 sensitizes bladder cancer to chemotherapy resistance via TRIP12-PPP1CB-YBX1 axis27
HOTAIR/Sp1/miR-199a critically regulates cancer stemness and malignant progression of cutaneous squamous cell carcinoma27
A proof of concept for targeting the PrPC - Amyloid β peptide interaction in basal prostate cancer and mesenchymal colon cancer27
LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination27
AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer27
PPP2R1A mutations cause ATR inhibitor sensitivity in ovarian clear cell carcinoma27
Selective inhibition of CDK9 in triple negative breast cancer27
Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 127
Leveraging RAS-mSIN1 interaction to selectively inhibit mTORC2 employing competitive RAS binding peptide: implications in breast cancer metastasis27
Alcohol-driven metabolic reprogramming promotes development of RORγt-deficient thymic lymphoma26
Retraction Note: E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage26
Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation26
Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGFβ signaling26
Correction: Enhanced YB1/EphA2 axis signaling promotes acquired resistance to sunitinib and metastatic potential in renal cell carcinoma26
Editorial Expression of Concern: Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4–miR-18a pathway in cervical cancer26
PP2A-B55: substrates and regulators in the control of cellular functions26
Ubiquitin and ubiquitin-like proteins in HPV-driven carcinogenesis26
Retraction Note: Aurora-A is a determinant of tamoxifen sensitivity through phosphorylation of ERα in breast cancer26
JAK2/ULK1 axis promotes cervical cancer progression by autophagy induction and SRPK1 phosphorylation26
TTPAL promotes gastric tumorigenesis by directly targeting NNMT to activate PI3K/AKT signaling26
ScRNA-seq of gastric cancer tissues reveals differences in the immune microenvironment of primary tumors and metastases25
GNAO1 overexpression promotes neural differentiation of glioma stem-like cells and reduces tumorigenicity through TRIM21/CREB/HES1 axis25
A novel lncRNA MTAR1 promotes cancer development through IGF2BPs mediated post-transcriptional regulation of c-MYC25
Importin-alpha transports Norrin to the nucleus to promote proliferation and Notch signaling in glioblastoma stem cells25
Neuropilin-2 promotes lineage plasticity and progression to neuroendocrine prostate cancer25
RETRACTED ARTICLE: Targeting HIF-1α/NOTCH1 pathway eliminates CD44+ cancer stem-like cell phenotypes, malignancy, and resistance to therapy in head and neck squamous cell carcinoma25
VprBP/DCAF1 regulates p53 function and stability through site-specific phosphorylation25
RNF126-mediated ubiquitination of FSP1 affects its subcellular localization and ferroptosis25
Loss of deubiquitylase USP2 triggers development of glioblastoma via TGF-β signaling25
Appearance of tuft cells during prostate cancer progression25
A novel integrated approach to predicting cancer immunotherapy efficacy25
PELO facilitates PLK1-induced the ubiquitination and degradation of Smad4 and promotes the progression of prostate cancer25
Single-cell RNA-seq recognized the initiator of epithelial ovarian cancer recurrence25
Of travelling homeoproteins and medulloblastomas25
GSTO1 aggravates EGFR-TKIs resistance and tumor metastasis via deglutathionylation of NPM1 in lung adenocarcinoma25
Integrative metabolomic characterization identifies plasma metabolomic signature in the diagnosis of papillary thyroid cancer24
Pan-RAS inhibitors and polo-like kinase 1: promising targets in colorectal cancer24
Correction: Repression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma24
M6A-mediated-upregulation of lncRNA BLACAT3 promotes bladder cancer angiogenesis and hematogenous metastasis through YBX3 nuclear shuttling and enhancing NCF2 transcription24
CD73 induces GM-CSF/MDSC-mediated suppression of T cells to accelerate pancreatic cancer pathogenesis24
Correction: TSPAN6 is a suppressor of Ras-driven cancer24
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma24
Origin and Evolution of RAS Membrane Targeting24
The role of α-klotho in human cancer: molecular and clinical aspects24
WTAP-mediated m6A methylation of PHF19 facilitates cell cycle progression by remodeling the accessible chromatin landscape in t(8;21) AML24
Correction: Alpelisib and fulvestrant in PIK3CA-mutated hormone receptor-positive HER2-negative advanced breast cancer included in the French early access program24
NeuroD1 drives a KAT2A-FDFT1 signaling axis to promote cholesterol biosynthesis and hepatocellular carcinoma progression via histone H3K27 acetylation24
Retraction Note: MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer24
Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers24
Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 624
Protein disulfide isomerase-enriched extracellular vesicles from bladder cancer cells support tumor survival and malignant transformation in the bladder24
Repurposed pizotifen malate targeting NRF2 exhibits anti-tumor activity through inducing ferroptosis in esophageal squamous cell carcinoma24
DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth24
Correction: Novel targeted mtLivin nanoparticles treatment for disseminated diffuse large B-cell lymphoma24
SMARCE1 promotes neuroblastoma tumorigenesis through assisting MYCN-mediated transcriptional activation24
UBXN2A suppresses the Rictor-mTORC2 signaling pathway, an established tumorigenic pathway in human colorectal cancer23
Circulating extracellular vesicles protein expression for early prediction of platinum-resistance in high-grade serous ovarian cancer23
Exosomal circSPIRE1 mediates glycosylation of E-cadherin to suppress metastasis of renal cell carcinoma23
Correction: Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca2+/PI3K/AKT pathway23
GDP-mannose 4,6-dehydratase is a key driver of MYCN-amplified neuroblastoma core fucosylation and tumorigenesis23
p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs23
Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer23
HMGB1/SET/HAT1 complex-mediated SASH1 repression drives glycolysis and metastasis in lung adenocarcinoma23
Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment23
The E3 ligase COP1 promotes ERα signaling and suppresses EMT in breast cancer23
BCL-2 isoform β promotes angiogenesis by TRiC-mediated upregulation of VEGF-A in lymphoma23
Subsets of cancer cells expressing CX3CR1 are endowed with metastasis-initiating properties and resistance to chemotherapy23
Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer23
Cancer-associated fibroblasts promote EGFR-TKI resistance via the CTHRC1/glycolysis/H3K18la positive feedback loop23
Epigenetics behind tumor immunology: a mini review23
Amyloid-like p53 as prognostic biomarker in serous ovarian cancer—a study of the OVCAD consortium23
EphA2 regulates vascular permeability and prostate cancer metastasis via modulation of cell junction protein phosphorylation23
Fulvestrant and everolimus efficacy after CDK4/6 inhibitor: a prospective study with circulating tumor DNA analysis22
Correction: Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL22
Correction: CEACAM1 impedes thyroid cancer growth but promotes invasiveness: a putative mechanism for early metastases22
IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma22
TWIST1 is a critical downstream target of the HGF/MET pathway and is required for MET driven acquired resistance in oncogene driven lung cancer22
Correction: CUL4B promotes gastric cancer invasion and metastasis-involvement of upregulation of HER222
TMIGD1: Emerging functions of a tumor supressor and adhesion receptor22
Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies22
Targeting RBM39 suppresses tumor growth and sensitizes osteosarcoma cells to cisplatin22
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