(The TQCC of Oncogene is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-06-01 to 2024-06-01.)
Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer340
A risk model developed based on tumor microenvironment predicts overall survival and associates with tumor immunity of patients with lung adenocarcinoma141
Aberrant NSUN2-mediated m5C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma140
A novel hypoxic long noncoding RNA KB-1980E6.3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability134
LNC942 promoting METTL14-mediated m6A methylation in breast cancer cell proliferation and progression133
Targeting telomerase for cancer therapy125
High-metastatic cancer cells derived exosomal miR92a-3p promotes epithelial-mesenchymal transition and metastasis of low-metastatic cancer cells by regulating PTEN/Akt pathway in hepatocellular carcin125
Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations119
The functional roles of TCA cycle metabolites in cancer118
Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines112
Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity111
Multifaceted role of branched-chain amino acid metabolism in cancer102
Metabolic rewiring in the promotion of cancer metastasis: mechanisms and therapeutic implications102
Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivo99
Emerging role of bacterial extracellular vesicles in cancer95
HGF/c-MET pathway in cancer: from molecular characterization to clinical evidence94
HDAC inhibition potentiates anti-tumor activity of macrophages and enhances anti-PD-L1-mediated tumor suppression86
Hypoxic gastric cancer-derived exosomes promote progression and metastasis via MiR-301a-3p/PHD3/HIF-1α positive feedback loop83
STAT3 phosphorylation at Ser727 and Tyr705 differentially regulates the EMT–MET switch and cancer metastasis83
Receptor tyrosine kinases and cancer: oncogenic mechanisms and therapeutic approaches82
Counteracting CAR T cell dysfunction79
FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis78
Senescence as a therapeutically relevant response to CDK4/6 inhibitors77
Mutations in circulating tumor DNA predict primary resistance to systemic therapies in advanced hepatocellular carcinoma76
Hypoxic exosomal HIF-1α-stabilizing circZNF91 promotes chemoresistance of normoxic pancreatic cancer cells via enhancing glycolysis76
Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer76
The next tier of EGFR resistance mutations in lung cancer75
Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma74
RETRACTED ARTICLE: Mesenchymal stem cells-derived exosomal microRNA-139-5p restrains tumorigenesis in bladder cancer by targeting PRC172
LncRNA BCYRN1 inhibits glioma tumorigenesis by competitively binding with miR-619-5p to regulate CUEDC2 expression and the PTEN/AKT/p21 pathway71
Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy71
Loss and revival of androgen receptor signaling in advanced prostate cancer70
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy70
RETRACTED ARTICLE: MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer69
Epigenetic silencing of LncRNA LINC00261 promotes c-myc-mediated aerobic glycolysis by regulating miR-222-3p/HIPK2/ERK axis and sequestering IGF2BP167
Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors66
NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization65
CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB164
Understanding the role of integrins in breast cancer invasion, metastasis, angiogenesis, and drug resistance62
Partial EMT in head and neck cancer biology: a spectrum instead of a switch61
Turning up the heat on non-immunoreactive tumors: pyroptosis influences the tumor immune microenvironment in bladder cancer60
LncRNA SNHG11 facilitates tumor metastasis by interacting with and stabilizing HIF-1α59
Plasma exosomes from endometrial cancer patients contain LGALS3BP to promote endometrial cancer progression58
The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression57
Oncogenic functions and therapeutic targeting of EphA2 in cancer57
Nerve fibers in the tumor microenvironment in neurotropic cancer—pancreatic cancer and cholangiocarcinoma57
DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway56
The Hippo pathway oncoprotein YAP promotes melanoma cell invasion and spontaneous metastasis55
The role of MET in chemotherapy resistance55
METTL3-mediated m6A methylation of SPHK2 promotes gastric cancer progression by targeting KLF254
Is PD-L1 a consistent biomarker for anti-PD-1 therapy? The model of balstilimab in a virally-driven tumor54
METTL3 promotes intrahepatic cholangiocarcinoma progression by regulating IFIT2 expression in an m6A-YTHDF2-dependent manner54
Pathomechanisms in schwannoma development and progression54
A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination54
Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions53
Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma53
GBP2 enhances glioblastoma invasion through Stat3/fibronectin pathway53
VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk53
The role of natural killer cell in gastrointestinal cancer: killer or helper53
CircHIF1A regulated by FUS accelerates triple-negative breast cancer progression by modulating NFIB expression and translocation52
Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis52
Role of p38 MAP kinase in cancer stem cells and metastasis52
LncRNA SLC26A4-AS1 suppresses the MRN complex-mediated DNA repair signaling and thyroid cancer metastasis by destabilizing DDX552
Deoxycholic acid modulates the progression of gallbladder cancer through N6-methyladenosine-dependent microRNA maturation51
Spatial collagen stiffening promotes collective breast cancer cell invasion by reinforcing extracellular matrix alignment51
LncRNA MIR17HG promotes colorectal cancer liver metastasis by mediating a glycolysis-associated positive feedback circuit51
COL11A1 activates cancer-associated fibroblasts by modulating TGF-β3 through the NF-κB/IGFBP2 axis in ovarian cancer cells51
circSETD3 regulates MAPRE1 through miR-615-5p and miR-1538 sponges to promote migration and invasion in nasopharyngeal carcinoma50
Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer50
MAOA promotes prostate cancer cell perineural invasion through SEMA3C/PlexinA2/NRP1–cMET signaling49
Supercharging BRD4 with NUT in carcinoma49
HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers49
Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand48
N7-methylguanosine tRNA modification promotes tumorigenesis and chemoresistance through WNT/β-catenin pathway in nasopharyngeal carcinoma48
Tumor-associated macrophages promote PD-L1 expression in tumor cells by regulating PKM2 nuclear translocation in pancreatic ductal adenocarcinoma47
Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies47
Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment46
Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer46
A highly annotated database of genes associated with platinum resistance in cancer46
The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF245
CD8+ T effector and immune checkpoint signatures predict prognosis and responsiveness to immunotherapy in bladder cancer45
Long-chain fatty acyl-CoA synthetase 1 promotes prostate cancer progression by elevation of lipogenesis and fatty acid beta-oxidation45
PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer44
Going beyond Polycomb: EZH2 functions in prostate cancer44
E3 ubiquitin ligase UBR5 promotes pancreatic cancer growth and aerobic glycolysis by downregulating FBP1 via destabilization of C/EBPα44
Clocking cancer: the circadian clock as a target in cancer therapy44
Targeting STAT3 by a small molecule suppresses pancreatic cancer progression43
The ELF3-regulated lncRNA UBE2CP3 is over-stabilized by RNA–RNA interactions and drives gastric cancer metastasis via miR-138-5p/ITGA2 axis43
ApoC1 promotes the metastasis of clear cell renal cell carcinoma via activation of STAT343
Anoikis resistant gastric cancer cells promote angiogenesis and peritoneal metastasis through C/EBPβ-mediated PDGFB autocrine and paracrine signaling43
Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling43
Core transcriptional regulatory circuitries in cancer42
Parvimonas micra promotes colorectal tumorigenesis and is associated with prognosis of colorectal cancer patients42
C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism42
Myeloid-derived suppressor cells promote lung cancer metastasis by CCL11 to activate ERK and AKT signaling and induce epithelial-mesenchymal transition in tumor cells42
Tumor-derived exosomal long noncoding RNA LINC01133, regulated by Periostin, contributes to pancreatic ductal adenocarcinoma epithelial-mesenchymal transition through the Wnt/β-catenin pathway by sile42
Cancer biology and molecular genetics of A3 adenosine receptor42
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair42
Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein42
CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer42
PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer41
Antibody-based cancer therapy41
Functional characterization of uveal melanoma oncogenes41
STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway41
MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells41
N6-methyladenosine demethyltransferase FTO-mediated autophagy in malignant development of oral squamous cell carcinoma41
Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways40
The Scribble family in cancer: twentieth anniversary40
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer40
STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts39
Genome-wide CRISPR-cas9 knockout screening identifies GRB7 as a driver for MEK inhibitor resistance in KRAS mutant colon cancer39
The role of R-spondin proteins in cancer biology39
RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing39
Therapeutic targeting of the mitochondrial one-carbon pathway: perspectives, pitfalls, and potential38
LncRNA KTN1-AS1 promotes the progression of non-small cell lung cancer via sponging of miR-130a-5p and activation of PDPK138
Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis reduces pancreatic cancer metastasis38
Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance38
Metabolic reprogramming of ovarian cancer involves ACSL1-mediated metastasis stimulation through upregulated protein myristoylation38
YAP1 overexpression contributes to the development of enzalutamide resistance by induction of cancer stemness and lipid metabolism in prostate cancer37
Malignant peripheral nerve sheath tumor: models, biology, and translation37
Tumor-derived osteopontin drives the resident fibroblast to myofibroblast differentiation through Twist1 to promote breast cancer progression37
CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model37
Lymph node metastasis-derived gastric cancer cells educate bone marrow-derived mesenchymal stem cells via YAP signaling activation by exosomal Wnt5a37
Exosomal miR-4466 from nicotine-activated neutrophils promotes tumor cell stemness and metabolism in lung cancer metastasis36
CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway36
FGF19 and FGFR4 promotes the progression of gallbladder carcinoma in an autocrine pathway dependent on GPBAR1-cAMP-EGR1 axis36
CTHRC1 promotes liver metastasis by reshaping infiltrated macrophages through physical interactions with TGF-β receptors in colorectal cancer36
Wild-type isocitrate dehydrogenase under the spotlight in glioblastoma36
How artificial intelligence might disrupt diagnostics in hematology in the near future35
The oxytocin receptor signalling system and breast cancer: a critical review35
The ER stress response mediator ERO1 triggers cancer metastasis by favoring the angiogenic switch in hypoxic conditions35
Polyploid giant cancer cells, stemness and epithelial-mesenchymal plasticity elicited by human cytomegalovirus35
A dysbiotic microbiome promotes head and neck squamous cell carcinoma35
Extracellular ATP promotes breast cancer invasion and chemoresistance via SOX9 signaling35
Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p to induce M2 macrophage polarization and promote glioma progression35
Transcription factors in colorectal cancer: molecular mechanism and therapeutic implications35
HDAC8 promotes the dissemination of breast cancer cells via AKT/GSK-3β/Snail signals35
KNSTRN promotes tumorigenesis and gemcitabine resistance by activating AKT in bladder cancer34
Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT34
CD73 induces GM-CSF/MDSC-mediated suppression of T cells to accelerate pancreatic cancer pathogenesis34
YTHDF2 is a potential target of AML1/ETO-HIF1α loop-mediated cell proliferation in t(8;21) AML34
FOXO3a-driven miRNA signatures suppresses VEGF-A/NRP1 signaling and breast cancer metastasis33
Small non-coding RNAs in human cancer: function, clinical utility, and characterization33
EphA2–YES1–ANXA2 pathway promotes gastric cancer progression and metastasis33
Molecular biological analysis of 5-FU-resistant gastric cancer organoids; KHDRBS3 contributes to the attainment of features of cancer stem cell33
Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling33
Meta-analysis of mucosal microbiota reveals universal microbial signatures and dysbiosis in gastric carcinogenesis32
Targeting mTOR signaling overcomes acquired resistance to combined BRAF and MEK inhibition in BRAF-mutant melanoma32
The HSF1/miR-135b-5p axis induces protective autophagy to promote oxaliplatin resistance through the MUL1/ULK1 pathway in colorectal cancer32
IGF1R acts as a cancer-promoting factor in the tumor microenvironment facilitating lung metastasis implantation and progression32
Tenascin C promotes cancer cell plasticity in mesenchymal glioblastoma32
CTGF regulates cell proliferation, migration, and glucose metabolism through activation of FAK signaling in triple-negative breast cancer32
POU1F1 transcription factor induces metabolic reprogramming and breast cancer progression via LDHA regulation32
N6-methyladenosine demethylase ALKBH5 suppresses malignancy of esophageal cancer by regulating microRNA biogenesis and RAI1 expression32
NK and NKT cells have distinct properties and functions in cancer32
Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis32
Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer32
POLE, POLD1, and NTHL1: the last but not the least hereditary cancer-predisposing genes32
Comprehensive characterisation of intronic mis-splicing mutations in human cancers32
SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer32
LINC00467 is up-regulated by TDG-mediated acetylation in non-small cell lung cancer and promotes tumor progression31
DNA methylome profiling of circulating tumor cells in lung cancer at single base-pair resolution31
SIX4 promotes hepatocellular carcinoma metastasis through upregulating YAP1 and c-MET31
Oroxylin A reverses hypoxia-induced cisplatin resistance through inhibiting HIF-1α mediated XPC transcription31
Aberrant activation of super enhancer and choline metabolism drive antiandrogen therapy resistance in prostate cancer30
Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice30
MCU-dependent negative sorting of miR-4488 to extracellular vesicles enhances angiogenesis and promotes breast cancer metastatic colonization30
Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges30
LncRNA GAL promotes colorectal cancer liver metastasis through stabilizing GLUT130
Deubiquitinase OTUB2 exacerbates the progression of colorectal cancer by promoting PKM2 activity and glycolysis30
Dexamethasone enhances the lung metastasis of breast cancer via a PI3K-SGK1-CTGF pathway30
p53 partial loss-of-function mutations sensitize to chemotherapy30
Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p5330
Pharmacologic conversion of cancer-associated fibroblasts from a protumor phenotype to an antitumor phenotype improves the sensitivity of pancreatic cancer to chemotherapeutics30
The m6A reading protein YTHDF3 potentiates tumorigenicity of cancer stem-like cells in ocular melanoma through facilitating CTNNB1 translation30
FGF18–FGFR2 signaling triggers the activation of c-Jun–YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential30
Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer29
M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression29
Functional genomics identifies new synergistic therapies for retinoblastoma29
MicroRNA determinants of neuroendocrine differentiation in metastatic castration-resistant prostate cancer29
Oncogenic Smurf1 promotes PTEN wild-type glioblastoma growth by mediating PTEN ubiquitylation29
The POU2F1-ALDOA axis promotes the proliferation and chemoresistance of colon cancer cells by enhancing glycolysis and the pentose phosphate pathway activity29
MYEOV increases HES1 expression and promotes pancreatic cancer progression by enhancing SOX9 transactivity29
Melatonin interrupts osteoclast functioning and suppresses tumor-secreted RANKL expression: implications for bone metastases29
NSD2 promotes tumor angiogenesis through methylating and activating STAT3 protein29
O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation29
Oct4 confers stemness and radioresistance to head and neck squamous cell carcinoma by regulating the homologous recombination factors PSMC3IP and RAD54L29
Androgen receptor promotes renal cell carcinoma (RCC) vasculogenic mimicry (VM) via altering TWIST1 nonsense-mediated decay through lncRNA-TANAR29
ST6Gal1 targets the ectodomain of ErbB2 in a site-specific manner and regulates gastric cancer cell sensitivity to trastuzumab29
The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer29
O-GlcNAc modified-TIP60/KAT5 is required for PCK1 deficiency-induced HCC metastasis28
EGFR activity addiction facilitates anti-ERBB based combination treatment of squamous bladder cancer28
Spontaneous and inherited TP53 genetic alterations28
Plectin is a regulator of prostate cancer growth and metastasis28
αSMA+ fibroblasts suppress Lgr5+ cancer stem cells and restrain colorectal cancer progression28
HuR up-regulates cell surface PD-L1 via stabilizing CMTM6 transcript in cancer28
Endogenous toxic metabolites and implications in cancer therapy28
Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF428
NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration28
Src: coordinating metabolism in cancer28
Cell-type deconvolution analysis identifies cancer-associated myofibroblast component as a poor prognostic factor in multiple cancer types28
Recent advances in preclinical models for lung squamous cell carcinoma28
CCL11 exacerbates colitis and inflammation-associated colon tumorigenesis28
S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK128
Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene27
The loss of SHMT2 mediates 5-fluorouracil chemoresistance in colorectal cancer by upregulating autophagy27
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma27
Melanoma stem cell maintenance and chemo-resistance are mediated by CD133 signal to PI3K-dependent pathways27
microRNA-93-5p promotes hepatocellular carcinoma progression via a microRNA-93-5p/MAP3K2/c-Jun positive feedback circuit27
A detailed characterization of stepwise activation of the androgen receptor variant 7 in prostate cancer cells27
BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors27
Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS27
Radiation-induced YAP activation confers glioma radioresistance via promoting FGF2 transcription and DNA damage repair27
STING protects breast cancer cells from intrinsic and genotoxic-induced DNA instability via a non-canonical, cell-autonomous pathway27
Epigenetic modification and a role for the E3 ligase RNF40 in cancer development and metastasis26
Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer26
Epiregulin confers EGFR-TKI resistance via EGFR/ErbB2 heterodimer in non-small cell lung cancer26
PP2A-B55: substrates and regulators in the control of cellular functions26
LIMK1 promotes peritoneal metastasis of gastric cancer and is a therapeutic target26
AR-induced long non-coding RNA LINC01503 facilitates proliferation and metastasis via the SFPQ-FOSL1 axis in nasopharyngeal carcinoma26
Going circular: history, present, and future of circRNAs in cancer26
OGT regulated O-GlcNAcylation promotes papillary thyroid cancer malignancy via activating YAP26
Modulation of DNA double-strand break repair as a strategy to improve precise genome editing26
Glioblastoma-associated microglia-derived exosomal circKIF18A promotes angiogenesis by targeting FOXC226
Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC26
CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of β-catenin26
miR-151a-3p-rich small extracellular vesicles derived from gastric cancer accelerate liver metastasis via initiating a hepatic stemness-enhancing niche26
KIAA1429 is a potential prognostic marker in colorectal cancer by promoting the proliferation via downregulating WEE1 expression in an m6A-independent manner26
PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinoma26
Mutant APC promotes tumor immune evasion via PD-L1 in colorectal cancer25
FBP1 regulates proliferation, metastasis, and chemoresistance by participating in C-MYC/STAT3 signaling axis in ovarian cancer25
Positive feedback regulation of lncRNA PVT1 and HIF2α contributes to clear cell renal cell carcinoma tumorigenesis and metastasis25
Exome sequencing identifies ARID2 as a novel tumor suppressor in early-onset sporadic rectal cancer25
Mutant collagen COL11A1 enhances cancerous invasion25
Applicability of liquid biopsies to represent the mutational profile of tumor tissue from different cancer entities25
Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis25
IMPAD1 and KDELR2 drive invasion and metastasis by enhancing Golgi-mediated secretion25
SOX9 is a critical regulator of TSPAN8-mediated metastasis in pancreatic cancer25
SRT1720 inhibits the growth of bladder cancer in organoids and murine models through the SIRT1-HIF axis25
Glioblastoma heterogeneity at single cell resolution25
CircKDM4B suppresses breast cancer progression via the miR-675/NEDD4L axis25
N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing25
miR-21a in exosomes from Lewis lung carcinoma cells accelerates tumor growth through targeting PDCD4 to enhance expansion of myeloid-derived suppressor cells25
The proprotein convertase furin in cancer: more than an oncogene25
The chromosome 21 kinase DYRK1A: emerging roles in cancer biology and potential as a therapeutic target25
G9a controls pluripotent-like identity and tumor-initiating function in human colorectal cancer25
Inactivation of EGLN3 hydroxylase facilitates Erk3 degradation via autophagy and impedes lung cancer growth25
YTHDF2 promotes multiple myeloma cell proliferation via STAT5A/MAP2K2/p-ERK axis25
C1GALT1 high expression is associated with poor survival of patients with pancreatic ductal adenocarcinoma and promotes cell invasiveness through integrin αv25
Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic25