Oncogene

Papers
(The TQCC of Oncogene is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-03-01 to 2025-03-01.)
ArticleCitations
Retraction Note to: FOXC2 promotes colorectal cancer metastasis by directly targeting MET166
Retraction Note: Upregulation of long noncoding RNA ZEB1-AS1 promotes tumor metastasis and predicts poor prognosis in hepatocellular carcinoma159
Retraction Note: The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer128
Retraction Note: RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine127
Retraction Note: Genetic alterations of the NRP/B gene are associated with human brain tumors124
Retraction Note: CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells118
Alcohol-induced C/EBP β-driven VIRMA decreases oxidative stress and promotes pancreatic ductal adenocarcinoma growth and metastasis via the m6A/YTHDF2/SLC43A2 pathway116
Correction: p73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis105
Retraction Note: HBx/ERα complex-mediated LINC01352 downregulation promotes HBV-related hepatocellular carcinoma via the miR-135b-APC axis104
Retraction Note: Human papillomavirus type 77 E6 protein selectively inhibits p53-dependent transcription of proapoptotic genes following UV-B irradiation96
Correction: BRD4-specific PROTAC inhibits basal-like breast cancer partially through downregulating KLF5 expression94
Editorial Expression of Concern: Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma94
SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells92
METTL3-mediated N6-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF487
The Hippo-YAP signaling pathway drives CD24-mediated immune evasion in esophageal squamous cell carcinoma via macrophage phagocytosis85
Synthetic lethal combination of CHK1 and WEE1 inhibition for treatment of castration-resistant prostate cancer79
Flotillin-1 palmitoylation is essential for its stability and subsequent tumor promoting capabilities78
DHODH inhibition represents a therapeutic strategy and improves abiraterone treatment in castration-resistant prostate cancer77
TWIST1 is a critical downstream target of the HGF/MET pathway and is required for MET driven acquired resistance in oncogene driven lung cancer76
The nerve cells in gastrointestinal cancers: from molecular mechanisms to clinical intervention73
KLF5 regulates actin remodeling to enhance the metastasis of nasopharyngeal carcinoma72
miR-147b mediated suppression of DUSP8 promotes lung cancer progression72
Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma70
CRL2KLHDC3 and CRL1Fbxw7 cooperatively mediate c-Myc degradation68
ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions65
An integrated ceRNA network identifies miR-375 as an upregulated miRNA playing a tumor suppressive role in aggressive prostate cancer65
A prismatic view of the epigenetic-metabolic regulatory axis in breast cancer therapy resistance64
COL5A1 promotes triple-negative breast cancer progression by activating tumor cell-macrophage crosstalk64
Suppression of lysosome metabolism-meditated GARP/TGF-β1 complexes specifically depletes regulatory T cells to inhibit breast cancer metastasis63
Correction: Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL62
Correction: Regulation of cancer stem cell activity by thyroid hormone receptor β62
FAK-LINC01089 negative regulatory loop controls chemoresistance and progression of small cell lung cancer62
A noncanonical E3 ubiquitin ligase RNF41-mediated MYO1C stability promotes prostate cancer metastasis by inducing actin remodeling60
Synergistic effects of combined BET and FAK inhibition against Vestibular Schwannomas in NF2-related Schwannomatosis60
Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells60
Single-cell profiling reveals altered immune landscape and impaired NK cell function in gastric cancer liver metastasis59
Loss of RNA-binding protein CELF2 promotes acute leukemia development via FAT10-mTORC159
tRF-33-P4R8YP9LON4VDP inhibits gastric cancer progression via modulating STAT3 signaling pathway in an AGO2-dependent manner57
scRNA‐seq reveals the landscape of immune repertoire of PBMNCs in iMCD56
Correction: Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers56
Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks56
N6-methyladenosine modified TGFB2 triggers lipid metabolism reprogramming to confer pancreatic ductal adenocarcinoma gemcitabine resistance56
Alternative splicing of ALDOA confers tamoxifen resistance in breast cancer54
EZH2 PROTACs target EZH2- and FOXM1-associated oncogenic nodes, suppressing breast cancer cell growth54
RHNO1: at the crossroads of DNA replication stress, DNA repair, and cancer54
ALDH1A3 is the switch that determines the balance of ALDH+ and CD24−CD44+ cancer stem cells, EMT-MET, and glucose metabolism in breast cancer53
Characterisation of APOBEC3B-Mediated RNA editing in breast cancer cells reveals regulatory roles of NEAT1 and MALAT1 lncRNAs53
NSUN2 regulates Wnt signaling pathway depending on the m5C RNA modification to promote the progression of hepatocellular carcinoma53
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis52
Thymidylate synthase O-GlcNAcylation: a molecular mechanism of 5-FU sensitization in colorectal cancer52
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer52
m6A-driven NAT10 translation facilitates fatty acid metabolic rewiring to suppress ferroptosis and promote ovarian tumorigenesis through enhancing ACOT7 mRNA acetylation52
Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies51
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma50
Emergence of β1 integrin-deficient breast tumours from dormancy involves both inactivation of p53 and generation of a permissive tumour microenvironment50
PTPRZ1 dephosphorylates and stabilizes RNF26 to reduce the efficacy of TKIs and PD-1 blockade in ccRCC49
Breathing new insights into the role of mutant p53 in lung cancer48
Tumor-associated macrophages promote PD-L1 expression in tumor cells by regulating PKM2 nuclear translocation in pancreatic ductal adenocarcinoma48
Viral and cellular oncogenes promote immune evasion47
Hypoxia induced cellular and exosomal RPPH1 promotes breast cancer angiogenesis and metastasis through stabilizing the IGF2BP2/FGFR2 axis47
Correction: Regucalcin promotes dormancy of prostate cancer46
Overcoming acquired resistance to third-generation EGFR inhibitors by targeting activation of intrinsic apoptotic pathway through Mcl-1 inhibition, Bax activation, or both46
Oncogenic potential of BEST4 in colorectal cancer via activation of PI3K/Akt signaling46
Correction: Targeting the HIF-1α-IGFBP2 axis therapeutically reduces IGF1-AKT signaling and blocks the growth and metastasis of relapsed anaplastic Wilms tumor46
MAZ promotes tumor proliferation and immune evasion in lung adenocarcinoma46
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin44
Downregulation of LNMAS orchestrates partial EMT and immune escape from macrophage phagocytosis to promote lymph node metastasis of cervical cancer43
The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner43
LIGHT enhanced bispecific antibody armed T-cells to treat immunotherapy resistant colon cancer43
TRIM32 promotes radioresistance by disrupting TC45-STAT3 interaction in triple-negative breast cancer42
A micropeptide XBP1SBM encoded by lncRNA promotes angiogenesis and metastasis of TNBC via XBP1s pathway42
De novo expression of gastrokines in pancreatic precursor lesions impede the development of pancreatic cancer42
Trop-2, Na+/K+ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion42
EMT-mediated regulation of CXCL1/5 for resistance to anti-EGFR therapy in colorectal cancer42
SKAP2 suppresses inflammation-mediated tumorigenesis by regulating SHP-1 and SHP-242
p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain)41
GIPC2 interacts with Fzd7 to promote prostate cancer metastasis by activating WNT signaling41
Therapeutic targeting of BAP1/ASXL3 sub-complex in ASCL1-dependent small cell lung cancer41
USP13 promotes development and metastasis of high-grade serous ovarian carcinoma in a novel mouse model41
Discoidin Domain Receptor 2 orchestrates melanoma resistance combining phenotype switching and proliferation41
MiR-378a inhibits glucose metabolism by suppressing GLUT1 in prostate cancer41
IL-36 signalling enhances a pro-tumorigenic phenotype in colon cancer cells with cancer cell growth restricted by administration of the IL-36R antagonist41
H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth41
XAF1 destabilizes estrogen receptor α through the assembly of a BRCA1-mediated destruction complex and promotes estrogen-induced apoptosis40
CRL2KLHDC3 mediates p14ARF N-terminal ubiquitylation degradation to promote non-small cell lung carcinoma progression40
Identification of a novel Calpain-2-SRC feed-back loop as necessity for β-Catenin accumulation and signaling activation in hepatocellular carcinoma40
Molecular profiling of signet-ring-cell carcinoma (SRCC) from the stomach and colon reveals potential new therapeutic targets40
Correction: Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer40
IGF1R acts as a cancer-promoting factor in the tumor microenvironment facilitating lung metastasis implantation and progression40
Structure and function of MuvB complexes39
TFAM downregulation promotes autophagy and ESCC survival through mtDNA stress-mediated STING pathway39
CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME138
Identification of low-frequency variants of UGT1A3 associated with bladder cancer risk by next-generation sequencing38
ANKFN1 plays both protumorigenic and metastatic roles in hepatocellular carcinoma38
A comprehensive analysis of LMO2 pathogenic regulatory profile during T-lineage development and leukemic transformation38
Synthetic lethal kinases in Ras/p53 mutant squamous cell carcinoma38
MARK2 regulates chemotherapeutic responses through class IIa HDAC-YAP axis in pancreatic cancer37
ZnT7 RNAi favors RafGOFscrib−/−-induced tumor growth and invasion in Drosophila through JNK signaling pathway37
Transcription associated cyclin-dependent kinases as therapeutic targets for prostate cancer37
The role of miR-200b/c in balancing EMT and proliferation revealed by an activity reporter37
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma37
Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic37
In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun36
Gamma-glutamyltransferase 7 suppresses gastric cancer by cooperating with RAB7 to induce mitophagy36
SCD5-dependent inhibition of SPARC secretion hampers metastatic spreading and favors host immunity in a TNBC murine model36
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer36
EZH2 regulates a SETDB1/ΔNp63α axis via RUNX3 to drive a cancer stem cell phenotype in squamous cell carcinoma35
The roles of intratumour heterogeneity in the biology and treatment of pancreatic ductal adenocarcinoma35
Transcriptional regulation by MYC: an emerging new model35
Correction: The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress35
Linear ubiquitination of PTEN impairs its function to promote prostate cancer progression35
Identification of novel germline mutations in FUT7 and EXT1 linked with hereditary multiple exostoses35
The age of adult pilocytic astrocytoma cells35
Epiregulin confers EGFR-TKI resistance via EGFR/ErbB2 heterodimer in non-small cell lung cancer35
Regulator of calcineurin 1 gene isoform 4 in pancreatic ductal adenocarcinoma regulates the progression of tumor cells34
CRISPR screens identify a novel combination treatment targeting BCL-XL and WNT signaling for KRAS/BRAF-mutated colorectal cancers34
Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand34
Regulatory chromatin rewiring promotes metabolic switching during adaptation to oncogenic receptor tyrosine kinase inhibition34
Tumor resistance to radiotherapy is triggered by an ATM/TAK1-dependent-increased expression of the cellular prion protein34
Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR–ERBB2 pathway34
CXCR4 and CXCR7 signaling promotes tumor progression and obesity-associated epithelial-mesenchymal transition in prostate cancer cells34
Hypoxia induces chemoresistance to proteasome inhibitors through orchestrating deSUMOylation and ubiquitination of SRC-3 in multiple myeloma33
The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer33
Correction: LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation33
CPSF4 regulates circRNA formation and microRNA mediated gene silencing in hepatocellular carcinoma33
Aberrant CREB1 activation in prostate cancer disrupts normal prostate luminal cell differentiation33
The role of polyamines in gastric cancer33
Correction: SOX18 promotes gastric cancer metastasis through transactivating MCAM and CCL733
MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner33
Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity33
The extracellular-regulated protein kinase 5 (ERK5) enhances metastatic burden in triple-negative breast cancer through focal adhesion protein kinase (FAK)-mediated regulation of cell adhesion33
Oncogenic long intervening noncoding RNA Linc00284 promotes c-Met expression by sponging miR-27a in colorectal cancer33
YTHDF2 is a potential target of AML1/ETO-HIF1α loop-mediated cell proliferation in t(8;21) AML32
WAPL induces cervical intraepithelial neoplasia modulated with estrogen signaling without HPV E6/E732
αSMA+ fibroblasts suppress Lgr5+ cancer stem cells and restrain colorectal cancer progression32
NK and NKT cells have distinct properties and functions in cancer32
A micropeptide JunBP regulated by TGF-β promotes hepatocellular carcinoma metastasis32
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma32
A synergistic partnership between IL-33/ST2 and Wnt pathway through Bcl-xL drives gastric cancer stemness and metastasis32
Vaccinia-related kinase 2 drives pancreatic cancer progression by protecting Plk1 from Chfr-mediated degradation31
The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma31
Novel inhibition of AKR1C3 and androgen receptor axis by PTUPB synergizes enzalutamide treatment in advanced prostate cancer31
Long non-coding RNA TILR constitutively represses TP53 and apoptosis in lung cancer31
Monitoring the 5′UTR landscape reveals isoform switches to drive translational efficiencies in cancer31
MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells31
ST6GAL1 inhibits metastasis of hepatocellular carcinoma via modulating sialylation of MCAM on cell surface31
The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers31
Altered gut microbiome composition by appendectomy contributes to colorectal cancer30
NF-κB-activated SPRY4-IT1 promotes cancer cell metastasis by downregulating TCEB1 mRNA via Staufen1-mediated mRNA decay30
N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing30
Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells30
Genetic modifiers regulating DNA replication and double-strand break repair are associated with differences in mammary tumors in mouse models of Li-Fraumeni syndrome30
Dual role of WNT5A in promoting endothelial differentiation of glioma stem cells and angiogenesis of glioma derived endothelial cells30
PCNA regulates primary metabolism by scaffolding metabolic enzymes30
Whole-transcriptome and proteome analyses identify key differentially expressed mRNAs, miRNAs, lncRNAs and circRNAs associated with HCC30
Combination of chemotherapy with BRAF inhibitors results in effective eradication of malignant melanoma by preventing ATM-dependent DNA repair30
Spatiotemporal view of malignant histogenesis and macroevolution via formation of polyploid giant cancer cells30
Correction to: SFRP2 induces a mesenchymal subtype transition by suppression of SOX2 in glioblastoma29
The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis29
Serine-arginine protein kinase 1 (SRPK1) promotes EGFR-TKI resistance by enhancing GSK3β Ser9 autophosphorylation independent of its kinase activity in non-small-cell lung cancer29
Applicability of liquid biopsies to represent the mutational profile of tumor tissue from different cancer entities29
DNAJA1 promotes cancer metastasis through interaction with mutant p5329
LIMK2 promotes melanoma tumor growth and metastasis through G3BP1-ESM1 pathway-mediated apoptosis inhibition29
Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice29
EWI2 and its relatives in Tetraspanin-enriched membrane domains regulate malignancy29
LncRNA XIST regulates breast cancer stem cells by activating proinflammatory IL-6/STAT3 signaling29
TRIM59 is suppressed by androgen receptor and acts to promote lineage plasticity and treatment-induced neuroendocrine differentiation in prostate cancer29
KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer28
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer28
SOX10 deficiency-mediated LAMB3 upregulation determines the invasiveness of MAPKi-resistant melanoma28
AMPK-deficiency forces metformin-challenged cancer cells to switch from carbohydrate metabolism to ketogenesis to support energy metabolism28
New perspectives for targeting therapy in ALK-positive human cancers28
Correction to: A combination of novel NSC small molecule inhibitor along with doxorubicin inhibits proliferation of triple-negative breast cancer through metabolic reprogramming28
Fermitin family member 2 promotes melanoma progression by enhancing the binding of p-α-Pix to Rac1 to activate the MAPK pathway28
PSMD14 stabilizes estrogen signaling and facilitates breast cancer progression via deubiquitinating ERα28
RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status28
EZH2-Myc driven glioblastoma elicited by cytomegalovirus infection of human astrocytes28
Novel thrombospondin-1 transcript exhibits distinctive expression and activity in thyroid tumorigenesis28
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation28
TMIGD1: Emerging functions of a tumor supressor and adhesion receptor28
ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma28
Glioma immunotherapy enhancement and CD8-specific sialic acid cleavage by isocitrate dehydrogenase (IDH)-128
NUDT22 promotes cancer growth through pyrimidine salvage28
Deciphering glioma epitranscriptome: focus on RNA modifications27
RNA binding protein RBMS3 is a common EMT effector that modulates triple-negative breast cancer progression via stabilizing PRRX1 mRNA27
A novel amplification gene PCI domain containing 2 (PCID2) promotes colorectal cancer through directly degrading a tumor suppressor promyelocytic leukemia (PML)27
PGC-1α promotes colorectal carcinoma metastasis through regulating ABCA1 transcription27
Notch signaling regulates a metabolic switch through inhibiting PGC-1α and mitochondrial biogenesis in dedifferentiated liposarcoma27
MCPIP1 inhibits Wnt/β-catenin signaling pathway activity and modulates epithelial-mesenchymal transition during clear cell renal cell carcinoma progression by targeting miRNAs27
SMAD4 is critical in suppression of BRAF-V600E serrated tumorigenesis27
IER2-induced senescence drives melanoma invasion through osteopontin27
RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B227
Pathologists’ first opinions on barriers and facilitators of computational pathology adoption in oncological pathology: an international study27
YAP governs cellular adaptation to perturbation of glutamine metabolism by regulating ATF4-mediated stress response26
Retraction Note: YAP1-induced MALAT1 promotes epithelial–mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer26
miR-151a-3p-rich small extracellular vesicles derived from gastric cancer accelerate liver metastasis via initiating a hepatic stemness-enhancing niche26
FANCA deficiency promotes leukaemic progression by allowing the emergence of cells carrying oncogenic driver mutations26
MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex26
Lineage-restricted neoplasia driven by Myc defaults to small cell lung cancer when combined with loss of p53 and Rb in the airway epithelium26
Brg1 controls stemness and metastasis of pancreatic cancer through regulating hypoxia pathway26
ZNF545 loss promotes ribosome biogenesis and protein translation to initiate colorectal tumorigenesis in mice26
C/ebpα represses the oncogenic Runx3–Myc axis in p53-deficient osteosarcoma development26
Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity26
Nup54-induced CARM1 nuclear importation promotes gastric cancer cell proliferation and tumorigenesis through transcriptional activation and methylation of Notch226
Commonalities and differences in the mutational signature and somatic driver mutation landscape across solid and hollow viscus organs26
CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer26
Activation of invasion by oncogenic reprogramming of cholesterol metabolism via increased NPC1 expression and macropinocytosis26
Liprins in oncogenic signaling and cancer cell adhesion26
Polyploidy, EZH2 upregulation, and transformation in cytomegalovirus-infected human ovarian epithelial cells26
The role of R-spondin proteins in cancer biology26
TRAIP suppresses bladder cancer progression by catalyzing K48-linked polyubiquitination of MYC25
VPS35 promotes gastric cancer progression through integrin/FAK/SRC signalling-mediated IL-6/STAT3 pathway activation in a YAP-dependent manner25
FBXO28 suppresses liver cancer invasion and metastasis by promoting PKA-dependent SNAI2 degradation25
PRAME induces genomic instability in uveal melanoma25
DLGAP5 triggers proliferation and metastasis of bladder cancer by stabilizing E2F1 via USP1125
Alleviating hypoxia to improve cancer immunotherapy25
TKT-PARP1 axis induces radioresistance by promoting DNA double-strand break repair in hepatocellular carcinoma25
MYC directly transactivates CR2/CD21, the receptor of the Epstein–Barr virus, enhancing the viral infection of Burkitt lymphoma cells25
Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts25
GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation25
Glucocorticoid treatment influences prostate cancer cell growth and the tumor microenvironment via altered glucocorticoid receptor signaling in prostate fibroblasts25
USP11 potentiates HGF/AKT signaling and drives metastasis in hepatocellular carcinoma25
ERK hyperactivation serves as a unified mechanism of escape in intrinsic and acquired CDK4/6 inhibitor resistance in acral lentiginous melanoma25
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production25
The cytotoxicity of γδT cells in non-small cell lung cancer mediated via coordination of the BCL-2 and AKT pathways25
The urothelial gene regulatory network: understanding biology to improve bladder cancer management25
NRF2 has a splicing regulatory function involving the survival of motor neuron (SMN) in non-small cell lung cancer25
Blocking LBH expression causes replication stress and sensitizes triple-negative breast cancer cells to ATR inhibitor treatment24
IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma24
NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment24
Correction to: Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential24
Correction: LncFZD6 initiates Wnt/β-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation24
Correction to: p14ARF inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway24
Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL24
Alpelisib and fulvestrant in PIK3CA-mutated hormone receptor-positive HER2-negative advanced breast cancer included in the French early access program24
Overcoming resistance to programmed cell death protein 1 (PD-1) blockade with allogeneic invariant natural killer T-cells (iNKT)24
Regulation of Src tumor activity by its N-terminal intrinsically disordered region24
Correction: Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer24
Correction to: NF-κB mediates radio-sensitization by the PARP-1 inhibitor, AG-01469924
Correction: Activation of ErbB-2 via a hierarchical interaction between ErbB-2 and type I insulin-like growth factor receptor in mammary tumor cells24
MZF1 mediates oncogene-induced senescence by promoting the transcription of p16INK4A24
SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling24
BTLA+CD200+ B cells dictate the divergent immune landscape and immunotherapeutic resistance in metastatic vs. primary pancreatic cancer24
Safety and efficacy of prophylactic and therapeutic vaccine based on live-attenuated Listeria monocytogenes in hepatobiliary cancers24
Correction: Nuclear translocation of IGF-1R via p150Glued and an importin-β/RanBP2-dependent pathway in cancer cells24
Correction: CEACAM1 impedes thyroid cancer growth but promotes invasiveness: a putative mechanism for early metastases24
Correction: CUL4B promotes gastric cancer invasion and metastasis-involvement of upregulation of HER224
Regulation of cancer stem cell activity by thyroid hormone receptor β24
PTEN-regulated PI3K-p110 and AKT isoform plasticity controls metastatic prostate cancer progression24
A SNAI2-PEAK1-INHBA stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting subpopulations of tumor cells positive for antiapoptotic and stress signaling 23
0.051074028015137