Oncogene

Papers
(The TQCC of Oncogene is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Correction: Regulation of cancer stem cell activity by thyroid hormone receptor β271
Identification of novel germline mutations in FUT7 and EXT1 linked with hereditary multiple exostoses210
Correction: Targeting the HIF-1α-IGFBP2 axis therapeutically reduces IGF1-AKT signaling and blocks the growth and metastasis of relapsed anaplastic Wilms tumor168
Retraction Note: CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells105
Retraction Note: Fermitin family member 2 promotes melanoma progression by enhancing the binding of p-α-Pix to Rac1 to activate the MAPK pathway103
Notch signaling regulates a metabolic switch through inhibiting PGC-1α and mitochondrial biogenesis in dedifferentiated liposarcoma100
H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth97
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer95
SOX10 deficiency-mediated LAMB3 upregulation determines the invasiveness of MAPKi-resistant melanoma95
LncRNA XIST regulates breast cancer stem cells by activating proinflammatory IL-6/STAT3 signaling93
RAD51-mediated homologous recombination is a pro-tumour driver pathway93
Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells93
tRF-33-P4R8YP9LON4VDP inhibits gastric cancer progression via modulating STAT3 signaling pathway in an AGO2-dependent manner88
LIGHT enhanced bispecific antibody armed T-cells to treat immunotherapy resistant colon cancer87
Deciphering glioma epitranscriptome: focus on RNA modifications86
Vimentin intermediate filaments orchestrate DNA nonhomologous end joining repair and lipolysis after DNA damage74
Gamma-glutamyltransferase 7 suppresses gastric cancer by cooperating with RAB7 to induce mitophagy73
Increased antiandrogen enzalutamide sensitivity via altering prostate cancer stem cell traits through modulating the androgen receptor-mediated CDR1/circCDR1-AS/miR-1290/BMP4 signaling73
The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis70
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin69
BTLA+CD200+ B cells dictate the divergent immune landscape and immunotherapeutic resistance in metastatic vs. primary pancreatic cancer69
GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation68
Correction: Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer67
ANKFN1 plays both protumorigenic and metastatic roles in hepatocellular carcinoma65
Correction: DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity64
USP5 deubiquitinates and stabilizes IMPDH2, to promote hepatocellular carcinoma progression62
Structure and function of MuvB complexes61
A comprehensive analysis of LMO2 pathogenic regulatory profile during T-lineage development and leukemic transformation61
SCD5-dependent inhibition of SPARC secretion hampers metastatic spreading and favors host immunity in a TNBC murine model60
SKAP2 suppresses inflammation-mediated tumorigenesis by regulating SHP-1 and SHP-259
METTL3-mediated N6-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF458
Trop-2, Na+/K+ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion57
Hypoxia induces chemoresistance to proteasome inhibitors through orchestrating deSUMOylation and ubiquitination of SRC-3 in multiple myeloma57
RETRACTED ARTICLE: Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma57
RBMS3-loss impedes TRIM21-induced ubiquitination of ANGPT2 in an RNA-independent manner and drives sorafenib resistance in hepatocellular carcinoma56
ALDH1A3 is the switch that determines the balance of ALDH+ and CD24−CD44+ cancer stem cells, EMT-MET, and glucose metabolism in breast cancer56
Correction: S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia55
Spatiotemporal view of malignant histogenesis and macroevolution via formation of polyploid giant cancer cells54
MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex54
Correction to: Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential54
Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks54
Nup54-induced CARM1 nuclear importation promotes gastric cancer cell proliferation and tumorigenesis through transcriptional activation and methylation of Notch254
Induction of IL6/STAT3-dependent TRAIL expression that contributes to the therapeutic efficacy of osimertinib in EGFR mutant NSCLC cells53
Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis53
Retraction Note: Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis52
The lncRNA ST18-AS1 suppresses pancreatic cancer progression by enhancing ST18 mRNA stability through anchoring FUS in the cytoplasm52
Editorial Expression of Concern: Role of BRCA1 in heat shock response52
PABPN1-C5 axis promotes hepatocellular carcinoma progression via NF-κB activation52
Correction: HMGB1 correlates with angiogenesis and poor prognosis of perihilar cholangiocarcinoma via elevating VEGFR2 of vessel endothelium51
Membrane flexibility induced by BST2 contributes to radioresistance in glioblastoma51
Correction: Exosomal circCARM1 from spheroids reprograms cell metabolism by regulating PFKFB2 in breast cancer50
Correction: MZF1 mediates oncogene-induced senescence by promoting the transcription of p16INK4A50
RNA-sequencing predicts a role of androgen receptor and aldehyde dehydrogenase 1A1 in osteosarcoma lung metastases50
RB loss determines selective resistance and novel vulnerabilities in ER-positive breast cancer models49
STT3A-mediated viral N-glycosylation underlies the tumor selectivity of oncolytic virus M148
Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF26347
Correction: MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP147
Correction: Editorial Expression of Concern: Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer47
Correction to: Ionizing radiation-induced NF-κB activation requires PARP-1 function to confer radioresistance47
Correction: An FGFR-p53 developmental signaling axis drives salivary cancer progression46
Revealing the tumor suppressive sequence within KL1 domain of the hormone Klotho46
The protection of UCK2 protein stability by GART maintains pyrimidine salvage synthesis for HCC growth under glucose limitation46
PRSS23-eIF4E-c-Myc axis promotes gastric tumorigenesis and progression46
Alternative splicing in prostate cancer progression and therapeutic resistance45
Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis45
Transferrin receptor 1 promotes the fibroblast growth factor receptor-mediated oncogenic potential of diffused-type gastric cancer45
Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction44
Single-cell multiomics reveals a gene regulatory circuit driving leukemia cell differentiation44
Correction to: Cervical squamous cell carcinoma-secreted exosomal miR-221-3p promotes lymphangiogenesis and lymphatic metastasis by targeting VASH143
RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP243
The platelet pannexin 1-IL-1β axis orchestrates pancreatic ductal adenocarcinoma invasion and metastasis43
AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors43
CircKDM4B suppresses breast cancer progression via the miR-675/NEDD4L axis42
Recent insights into the causes and consequences of chromosome mis-segregation42
CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-inducing phenotype41
Pancreatic ductal adenocarcinoma induces neural injury that promotes a transcriptomic and functional repair signature by peripheral neuroglia41
AGO4 suppresses tumor growth by modulating autophagy and apoptosis via enhancing TRIM21-mediated ubiquitination of GRP78 in a p53-independent manner41
Post-transcriptional control of gene expression by β-catenin: expanding the non-canonical ARMoury41
Extracellular vesicles of cancer cells induce FOXP3+ fibroblasts and facilitate tumor invasion via the Wnt3-β-catenin pathway41
Delactylase effects of SIRT1 on a positive feedback loop involving the H19-glycolysis-histone lactylation in gastric cancer40
Crosstalk between endothelial progenitor cells and HCC through periostin/CCL2/CD36 supports formation of the pro-metastatic microenvironment in HCC40
Correction to: EphA2–YES1–ANXA2 pathway promotes gastric cancer progression and metastasis40
BRD4 regulates PAI-1 expression in tumor-associated macrophages to drive chemoresistance in colorectal cancer39
Matriptase-2/NR4A3 axis switches TGF-β action toward suppression of prostate cancer cell invasion, tumor growth, and metastasis39
Functional screening reveals HORMAD1-driven gene dependencies associated with translesion synthesis and replication stress tolerance39
Tumor cell-derived ANGPTL2 promotes β-catenin-driven intestinal tumorigenesis39
OLFM4 deficiency delays the progression of colitis to colorectal cancer by abrogating PMN-MDSCs recruitment39
ROS production by mitochondria: function or dysfunction?39
Correction: NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment38
Correction: PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production38
Correction to: Long non-coding RNA KRT19P3 suppresses proliferation and metastasis through COPS7A-mediated NF-κB pathway in gastric cancer38
PIM1 drives lipid droplet accumulation to promote proliferation and survival in prostate cancer37
Ac4C modification of lncRNA SIMALR promotes nasopharyngeal carcinoma progression through activating eEF1A2 to facilitate ITGB4/ITGA6 translation37
Decitabine enhances targeting of AML cells by NY-ESO-1-specific TCR-T cells and promotes the maintenance of effector function and the memory phenotype37
E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer37
The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-Raf and MAPK signaling cascade37
SIRT7: a novel molecular target for personalized cancer treatment?37
SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity37
Correction: ROR1-targeting switchable CAR-T cells for cancer therapy36
Tumor-mesothelium HOXA11-PDGF BB/TGF β1-miR-181a-5p-Egr1 feedforward amplifier circuity propels mesothelial fibrosis and peritoneal metastasis of gastric cancer36
Cyclin E1 overexpression sensitizes ovarian cancer cells to WEE1 and PLK1 inhibition36
Correction: Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E36
Correction: Targeting MERTK on tumour cells and macrophages: a potential intervention for sporadic and NF2-related meningioma and schwannoma tumours36
The kinesin KIF20A promotes progression to castration-resistant prostate cancer through autocrine activation of the androgen receptor35
C4orf19 inhibits colorectal cancer cell proliferation by competitively binding to Keap1 with TRIM25 via the USP17/Elk-1/CDK6 axis35
Phosphorylation of USP27X by PIM2 promotes glycolysis and breast cancer progression via deubiquitylation of MYC35
Mesenchymal stromal cells confer breast cancer doxorubicin resistance by producing hyaluronan35
METTL3 promotes cellular senescence of colorectal cancer via modulation of CDKN2B transcription and mRNA stability35
Muc16 depletion diminishes KRAS-induced tumorigenesis and metastasis by altering tumor microenvironment factors in pancreatic ductal adenocarcinoma35
Inactivation of EGLN3 hydroxylase facilitates Erk3 degradation via autophagy and impedes lung cancer growth34
Decoding the adaptive survival mechanisms of breast cancer dormancy34
RB1 loss in castration-resistant prostate cancer confers vulnerability to LSD1 inhibition34
Tumor innervation is triggered by endoplasmic reticulum stress34
Stabilization of MOF (KAT8) by USP10 promotes esophageal squamous cell carcinoma proliferation and metastasis through epigenetic activation of ANXA2/Wnt signaling34
Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis34
Engineering prostate cancer in vitro: what does it take?34
Therapeutic targeting the oncogenic driver EWSR1::FLI1 in Ewing sarcoma through inhibition of the FACT complex34
Enhanced anti-cancer efficacy of arginine deaminase expressed by tumor-seeking Salmonella Gallinarum33
YBX1 promotes 5-Fluorouracil resistance in gastric cancer via m5C-dependent ATG9A mRNA stabilization through autophagy33
The influence of endothelial metabolic reprogramming on the tumor microenvironment33
MicroRNAs: circulating biomarkers for the early detection of imperceptible cancers via biosensor and machine-learning advances33
Feedback activation of EGFR/wild-type RAS signaling axis limits KRASG12D inhibitor efficacy in KRASG12D-mutated colorectal cancer33
OTUB1 suppresses Hippo signaling via modulating YAP protein in gastric cancer33
Correction to: Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA5532
A multi-faceted discovery strategy identifies functional antibodies binding to cysteine-rich domain 1 of hDKK1 for cancer immunotherapy via Wnt non-canonical pathway32
Correction: Loss-of-function mutations of SOX17 lead to YAP/TEAD activation-dependent malignant transformation in endometrial cancer32
Retraction Note: Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor32
Correction: Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma32
Correction: IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma31
Lysine metabolism is a novel metabolic tumor suppressor pathway in breast cancer31
CBX3 accelerates the malignant progression of glioblastoma multiforme by stabilizing EGFR expression31
Correction to: Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation31
Retraction Note: Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1α levels contribute to emergence of an aggressive phenotype in prostat31
Shallow whole genome re-sequencing to precisely predict benefit from PARP inhibitor31
Correction: Combination strategies with PARP inhibitors in BRCA-mutated triple-negative breast cancer: overcoming resistance mechanisms31
Molecular explorations of cancer biology and therapeutics at PDB-10131
Correction: The ELF3-regulated lncRNA UBE2CP3 is over-stabilized by RNA–RNA interactions and drives gastric cancer metastasis via miR-138-5p/ITGA2 axis31
Editorial Expression of Concern: Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress31
Editorial Expression of Concern: Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene30
Targeting SLP2-mediated lipid metabolism reprograming restricts proliferation and metastasis of hepatocellular carcinoma and promotes sensitivity to Lenvatinib30
ARHGAP–RhoA signaling provokes homotypic adhesion-triggered cell death of metastasized diffuse-type gastric cancer30
Leveraging RAS-mSIN1 interaction to selectively inhibit mTORC2 employing competitive RAS binding peptide: implications in breast cancer metastasis30
Correction: Transactivation of human endogenous retrovirus K (HERV-K) by KSHV promotes Kaposi’s sarcoma development30
HJURP is recruited to double-strand break sites and facilitates DNA repair by promoting chromatin reorganization30
Celastrol recruits UBE3A to recognize and degrade the DNA binding domain of steroid receptors30
Phosphorylation of FOXK2 at Thr13 and Ser30 by PDK2 sustains glycolysis through a positive feedback manner in ovarian cancer29
The role of miR-92b-3p in notch signaling and monitoring of oral squamous cell carcinoma29
The immunological role of ADAMs in the field of gastroenterological chronic inflammatory diseases and cancers: a review29
Clustering single-cell RNA sequencing data via iterative smoothing and self-supervised discriminative embedding29
Long non-coding RNA-MIR181A1HG acts as an oncogene and contributes to invasion and metastasis in gastric cancer29
sEV-mediated intercellular transformation from MGAT4AHigh to MGAT4ALow tumor cells via the HOTAIRM1/miR-196b-5p axis promotes apoptosis resistance in CTCL29
The strategy and clinical relevance of in vitro models of MAP resistance in osteosarcoma: a systematic review29
Inactivation of kindlin-3 increases human melanoma aggressiveness through the collagen-activated tyrosine kinase receptor DDR129
A proof of concept for targeting the PrPC - Amyloid β peptide interaction in basal prostate cancer and mesenchymal colon cancer29
circIPO7 dissociates caprin-1 from ribosomes and inhibits gastric cancer cell proliferation by suppressing EGFR and mTOR29
Chemerin enhances mesenchymal features of glioblastoma by establishing autocrine and paracrine networks in a CMKLR1-dependent manner28
Selective inhibition of CDK9 in triple negative breast cancer28
Comprehensive single-cell analysis reveals mast cells’ roles in cancer immunity28
AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer28
PPDPF promotes lung adenocarcinoma progression via inhibiting apoptosis and NK cell-mediated cytotoxicity through STAT328
Single-cell landscape of undifferentiated pleomorphic sarcoma28
KDM1A-driven RNF81 downregulation promotes gastric cancer progression via KLF4 destabilization28
Zinc ions activate AKT and promote prostate cancer cell proliferation via disrupting AKT intramolecular interaction28
CircVPS8 promotes the malignant phenotype and inhibits ferroptosis of glioma stem cells by acting as a scaffold for MKRN1, SOX15 and HNF4A28
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer27
PPP2R1A mutations cause ATR inhibitor sensitivity in ovarian clear cell carcinoma27
LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination27
The proteomic characterization of the peritumor microenvironment in human hepatocellular carcinoma27
The multifaceted role of EGLN family prolyl hydroxylases in cancer: going beyond HIF regulation27
Retraction Note: E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage27
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations27
O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation27
Retraction Note: Aurora-A is a determinant of tamoxifen sensitivity through phosphorylation of ERα in breast cancer27
A novel lncRNA MTAR1 promotes cancer development through IGF2BPs mediated post-transcriptional regulation of c-MYC26
Importin-alpha transports Norrin to the nucleus to promote proliferation and Notch signaling in glioblastoma stem cells26
Engineered targeting OIP5 sensitizes bladder cancer to chemotherapy resistance via TRIP12-PPP1CB-YBX1 axis26
JAK2/ULK1 axis promotes cervical cancer progression by autophagy induction and SRPK1 phosphorylation26
Correction: Enhanced YB1/EphA2 axis signaling promotes acquired resistance to sunitinib and metastatic potential in renal cell carcinoma26
WTAP-mediated m6A methylation of PHF19 facilitates cell cycle progression by remodeling the accessible chromatin landscape in t(8;21) AML26
Ubiquitin and ubiquitin-like proteins in HPV-driven carcinogenesis26
Correction: Repression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma26
A novel integrated approach to predicting cancer immunotherapy efficacy26
Editorial Expression of Concern: Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4–miR-18a pathway in cervical cancer26
Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers26
Appearance of tuft cells during prostate cancer progression26
Origin and Evolution of RAS Membrane Targeting26
GNAO1 overexpression promotes neural differentiation of glioma stem-like cells and reduces tumorigenicity through TRIM21/CREB/HES1 axis26
Protein disulfide isomerase-enriched extracellular vesicles from bladder cancer cells support tumor survival and malignant transformation in the bladder26
Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 625
VprBP/DCAF1 regulates p53 function and stability through site-specific phosphorylation25
Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 125
Integrative metabolomic characterization identifies plasma metabolomic signature in the diagnosis of papillary thyroid cancer25
Targeting SREBP-dependent lipogenesis potentiates the anti-tumor activity of docetaxel by increasing membrane permeability and intracellular drug accumulation25
DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth25
M6A-mediated-upregulation of lncRNA BLACAT3 promotes bladder cancer angiogenesis and hematogenous metastasis through YBX3 nuclear shuttling and enhancing NCF2 transcription25
Loss of deubiquitylase USP2 triggers development of glioblastoma via TGF-β signaling25
Of travelling homeoproteins and medulloblastomas25
Pan-RAS inhibitors and polo-like kinase 1: promising targets in colorectal cancer25
RNF126-mediated ubiquitination of FSP1 affects its subcellular localization and ferroptosis24
NeuroD1 drives a KAT2A-FDFT1 signaling axis to promote cholesterol biosynthesis and hepatocellular carcinoma progression via histone H3K27 acetylation24
Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGFβ signaling24
Correction: Novel targeted mtLivin nanoparticles treatment for disseminated diffuse large B-cell lymphoma24
Single-cell RNA-seq recognized the initiator of epithelial ovarian cancer recurrence24
Correction: Alpelisib and fulvestrant in PIK3CA-mutated hormone receptor-positive HER2-negative advanced breast cancer included in the French early access program24
Neuropilin-2 promotes lineage plasticity and progression to neuroendocrine prostate cancer24
PELO facilitates PLK1-induced the ubiquitination and degradation of Smad4 and promotes the progression of prostate cancer24
The role of α-klotho in human cancer: molecular and clinical aspects24
Alcohol-driven metabolic reprogramming promotes development of RORγt-deficient thymic lymphoma24
Correction: TSPAN6 is a suppressor of Ras-driven cancer24
ScRNA-seq of gastric cancer tissues reveals differences in the immune microenvironment of primary tumors and metastases24
GSTO1 aggravates EGFR-TKIs resistance and tumor metastasis via deglutathionylation of NPM1 in lung adenocarcinoma24
RETRACTED ARTICLE: Targeting HIF-1α/NOTCH1 pathway eliminates CD44+ cancer stem-like cell phenotypes, malignancy, and resistance to therapy in head and neck squamous cell carcinoma24
Repurposed pizotifen malate targeting NRF2 exhibits anti-tumor activity through inducing ferroptosis in esophageal squamous cell carcinoma24
CD73 induces GM-CSF/MDSC-mediated suppression of T cells to accelerate pancreatic cancer pathogenesis24
Retraction Note: MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer24
Amyloid-like p53 as prognostic biomarker in serous ovarian cancer—a study of the OVCAD consortium23
Fulvestrant and everolimus efficacy after CDK4/6 inhibitor: a prospective study with circulating tumor DNA analysis23
Correction: Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca2+/PI3K/AKT pathway23
ECD, a novel androgen receptor target promotes prostate cancer tumorigenesis by regulating glycolysis23
Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer23
BCL-2 isoform β promotes angiogenesis by TRiC-mediated upregulation of VEGF-A in lymphoma23
Editorial Expression of Concern: RING finger-dependent ubiquitination by PRAJA is dependent on TGF-ß and potentially defines the functional status of the tumor suppressor ELF23
EphA2 regulates vascular permeability and prostate cancer metastasis via modulation of cell junction protein phosphorylation23
Cancer-associated fibroblasts promote EGFR-TKI resistance via the CTHRC1/glycolysis/H3K18la positive feedback loop23
Epigenetics behind tumor immunology: a mini review23
HMGB1/SET/HAT1 complex-mediated SASH1 repression drives glycolysis and metastasis in lung adenocarcinoma23
M7G modification of FTH1 and pri-miR-26a regulates ferroptosis and chemotherapy resistance in osteosarcoma23
p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs23
Persistent organic pollutants promote aggressiveness in prostate cancer22
GDP-mannose 4,6-dehydratase is a key driver of MYCN-amplified neuroblastoma core fucosylation and tumorigenesis22
Exosomal circSPIRE1 mediates glycosylation of E-cadherin to suppress metastasis of renal cell carcinoma22
JMJD6 in tumor-associated macrophage regulates macrophage polarization and cancer progression via STAT3/IL-10 axis22
RUVBL1 promotes enzalutamide resistance of prostate tumors through the PLXNA1-CRAF-MAPK pathway22
Nuclear translocation of Gasdermin D sensitizes colorectal cancer to chemotherapy in a pyroptosis-independent manner22
Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer22
UBXN2A suppresses the Rictor-mTORC2 signaling pathway, an established tumorigenic pathway in human colorectal cancer22
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma22
SMARCE1 promotes neuroblastoma tumorigenesis through assisting MYCN-mediated transcriptional activation22
GPER-mediated stabilization of HIF-1α contributes to upregulated aerobic glycolysis in tamoxifen-resistant cells22
Subsets of cancer cells expressing CX3CR1 are endowed with metastasis-initiating properties and resistance to chemotherapy22
Targeting RBM39 suppresses tumor growth and sensitizes osteosarcoma cells to cisplatin22
CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin22
Circulating extracellular vesicles protein expression for early prediction of platinum-resistance in high-grade serous ovarian cancer22
Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment22
Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis21
Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies21
DLGAP5 triggers proliferation and metastasis of bladder cancer by stabilizing E2F1 via USP1121
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma21
LIMK2 promotes centrosome clustering and cancer progression by activating MST4-mediated phosphorylation of NPM121
NRF2 has a splicing regulatory function involving the survival of motor neuron (SMN) in non-small cell lung cancer21
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