Oncogene

Article	Citations
Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer	310
YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation	197
Immune-based therapies for hepatocellular carcinoma	146
PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics	133
A risk model developed based on tumor microenvironment predicts overall survival and associates with tumor immunity of patients with lung adenocarcinoma	129
LNC942 promoting METTL14-mediated m6A methylation in breast cancer cell proliferation and progression	124
Aberrant NSUN2-mediated m5C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma	121
A novel hypoxic long noncoding RNA KB-1980E6.3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability	121
Combined PARP and ATR inhibition potentiates genome instability and cell death in ATM-deficient cancer cells	115
High-metastatic cancer cells derived exosomal miR92a-3p promotes epithelial-mesenchymal transition and metastasis of low-metastatic cancer cells by regulating PTEN/Akt pathway in hepatocellular carcin	114
Targeting telomerase for cancer therapy	112
Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations	109
Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines	106
Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity	98
The functional roles of TCA cycle metabolites in cancer	96
Metabolic rewiring in the promotion of cancer metastasis: mechanisms and therapeutic implications	95
Multifaceted role of branched-chain amino acid metabolism in cancer	95
Emerging role of bacterial extracellular vesicles in cancer	86
Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivo	85
Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer	84
HGF/c-MET pathway in cancer: from molecular characterization to clinical evidence	77
Hypoxic gastric cancer-derived exosomes promote progression and metastasis via MiR-301a-3p/PHD3/HIF-1α positive feedback loop	77
Modeling clear cell renal cell carcinoma and therapeutic implications	77
Radiation resistance in head and neck squamous cell carcinoma: dire need for an appropriate sensitizer	75
HDAC inhibition potentiates anti-tumor activity of macrophages and enhances anti-PD-L1-mediated tumor suppression	75

STAT3 phosphorylation at Ser727 and Tyr705 differentially regulates the EMT–MET switch and cancer metastasis	75
Mutations in circulating tumor DNA predict primary resistance to systemic therapies in advanced hepatocellular carcinoma	75
Counteracting CAR T cell dysfunction	71
Hypoxic exosomal HIF-1α-stabilizing circZNF91 promotes chemoresistance of normoxic pancreatic cancer cells via enhancing glycolysis	71
FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis	71
Receptor tyrosine kinases and cancer: oncogenic mechanisms and therapeutic approaches	71
Senescence as a therapeutically relevant response to CDK4/6 inhibitors	69
The next tier of EGFR resistance mutations in lung cancer	67
Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy	67
Breaking through the glioblastoma micro-environment via extracellular vesicles	67
LncRNA BCYRN1 inhibits glioma tumorigenesis by competitively binding with miR-619-5p to regulate CUEDC2 expression and the PTEN/AKT/p21 pathway	67
Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer	66
RETRACTED ARTICLE: Mesenchymal stem cells-derived exosomal microRNA-139-5p restrains tumorigenesis in bladder cancer by targeting PRC1	66
RETRACTED ARTICLE: MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer	66
Epigenetic silencing of LncRNA LINC00261 promotes c-myc-mediated aerobic glycolysis by regulating miR-222-3p/HIPK2/ERK axis and sequestering IGF2BP1	65
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy	64
Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma	64
p300/CBP inhibition enhances the efficacy of programmed death-ligand 1 blockade treatment in prostate cancer	64
Loss and revival of androgen receptor signaling in advanced prostate cancer	63
Turning up the heat on non-immunoreactive tumors: pyroptosis influences the tumor immune microenvironment in bladder cancer	60
Understanding the role of integrins in breast cancer invasion, metastasis, angiogenesis, and drug resistance	60
LncRNA SNHG11 facilitates tumor metastasis by interacting with and stabilizing HIF-1α	58
Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors	58
ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity	57
NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization	55
Ubiquitination-mediated degradation of SIRT1 by SMURF2 suppresses CRC cell proliferation and tumorigenesis	53
Plasma exosomes from endometrial cancer patients contain LGALS3BP to promote endometrial cancer progression	53
Oncogenic functions and therapeutic targeting of EphA2 in cancer	52
The role of MET in chemotherapy resistance	52
Partial EMT in head and neck cancer biology: a spectrum instead of a switch	51
METTL3-mediated m6A methylation of SPHK2 promotes gastric cancer progression by targeting KLF2	51
Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions	51
Nerve fibers in the tumor microenvironment in neurotropic cancer—pancreatic cancer and cholangiocarcinoma	50
LncRNA SLC26A4-AS1 suppresses the MRN complex-mediated DNA repair signaling and thyroid cancer metastasis by destabilizing DDX5	50
The Hippo pathway oncoprotein YAP promotes melanoma cell invasion and spontaneous metastasis	50
DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway	50
The role of natural killer cell in gastrointestinal cancer: killer or helper	50
The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression	50
Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities	49
Is PD-L1 a consistent biomarker for anti-PD-1 therapy? The model of balstilimab in a virally-driven tumor	49
A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination	49
Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma	49
TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness	48
Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand	48
circSETD3 regulates MAPRE1 through miR-615-5p and miR-1538 sponges to promote migration and invasion in nasopharyngeal carcinoma	48
CircHIF1A regulated by FUS accelerates triple-negative breast cancer progression by modulating NFIB expression and translocation	47
Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis	47
HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers	47
MAOA promotes prostate cancer cell perineural invasion through SEMA3C/PlexinA2/NRP1–cMET signaling	47
Deoxycholic acid modulates the progression of gallbladder cancer through N6-methyladenosine-dependent microRNA maturation	46

GBP2 enhances glioblastoma invasion through Stat3/fibronectin pathway	46
Pathomechanisms in schwannoma development and progression	46
CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1	45
Supercharging BRD4 with NUT in carcinoma	45
PDE4 subtypes in cancer	45
VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk	45
Spatial collagen stiffening promotes collective breast cancer cell invasion by reinforcing extracellular matrix alignment	45
LAMB3 promotes tumour progression through the AKT–FOXO3/4 axis and is transcriptionally regulated by the BRD2/acetylated ELK4 complex in colorectal cancer	45
METTL3 promotes intrahepatic cholangiocarcinoma progression by regulating IFIT2 expression in an m6A-YTHDF2-dependent manner	45
RAF kinase dimerization: implications for drug discovery and clinical outcomes	44
LncRNA MIR17HG promotes colorectal cancer liver metastasis by mediating a glycolysis-associated positive feedback circuit	44
TGF-β1 secreted by pancreatic stellate cells promotes stemness and tumourigenicity in pancreatic cancer cells through L1CAM downregulation	44
Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer	43
Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment	42
C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism	41
Targeting STAT3 by a small molecule suppresses pancreatic cancer progression	41
ApoC1 promotes the metastasis of clear cell renal cell carcinoma via activation of STAT3	41
Role of p38 MAP kinase in cancer stem cells and metastasis	41
Tumor-derived exosomal long noncoding RNA LINC01133, regulated by Periostin, contributes to pancreatic ductal adenocarcinoma epithelial-mesenchymal transition through the Wnt/β-catenin pathway by sile	41
Tumor-associated macrophages promote PD-L1 expression in tumor cells by regulating PKM2 nuclear translocation in pancreatic ductal adenocarcinoma	41
N7-methylguanosine tRNA modification promotes tumorigenesis and chemoresistance through WNT/β-catenin pathway in nasopharyngeal carcinoma	41
STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway	41
Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer	41
Loss of the nuclear Wnt pathway effector TCF7L2 promotes migration and invasion of human colorectal cancer cells	40
Identification of novel methylation markers in HPV-associated oropharyngeal cancer: genome-wide discovery, tissue verification and validation testing in ctDNA	40
The Scribble family in cancer: twentieth anniversary	40
COL11A1 activates cancer-associated fibroblasts by modulating TGF-β3 through the NF-κB/IGFBP2 axis in ovarian cancer cells	40
Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein	40
The ELF3-regulated lncRNA UBE2CP3 is over-stabilized by RNA–RNA interactions and drives gastric cancer metastasis via miR-138-5p/ITGA2 axis	40
PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer	40
CD8+ T effector and immune checkpoint signatures predict prognosis and responsiveness to immunotherapy in bladder cancer	40
A highly annotated database of genes associated with platinum resistance in cancer	39
Clocking cancer: the circadian clock as a target in cancer therapy	39
Core transcriptional regulatory circuitries in cancer	39
Going beyond Polycomb: EZH2 functions in prostate cancer	39
PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer	39
MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells	39
E3 ubiquitin ligase UBR5 promotes pancreatic cancer growth and aerobic glycolysis by downregulating FBP1 via destabilization of C/EBPα	39
Antibody-based cancer therapy	39
Functional characterization of uveal melanoma oncogenes	39
The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2	39
Anoikis resistant gastric cancer cells promote angiogenesis and peritoneal metastasis through C/EBPβ-mediated PDGFB autocrine and paracrine signaling	39
Cancer biology and molecular genetics of A3 adenosine receptor	38
The nuclear oncoprotein Fra-1: a transcription factor knocking on therapeutic applications’ door	38
Long-chain fatty acyl-CoA synthetase 1 promotes prostate cancer progression by elevation of lipogenesis and fatty acid beta-oxidation	38
Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling	38
Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling	37
LncRNA KTN1-AS1 promotes the progression of non-small cell lung cancer via sponging of miR-130a-5p and activation of PDPK1	37
STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts	37
Myeloid-derived suppressor cells promote lung cancer metastasis by CCL11 to activate ERK and AKT signaling and induce epithelial-mesenchymal transition in tumor cells	37
The β-catenin/TCF-4-LINC01278-miR-1258-Smad2/3 axis promotes hepatocellular carcinoma metastasis	37
Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis reduces pancreatic cancer metastasis	36
CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer	36
N6-methyladenosine demethyltransferase FTO-mediated autophagy in malignant development of oral squamous cell carcinoma	36
Parvimonas micra promotes colorectal tumorigenesis and is associated with prognosis of colorectal cancer patients	36
Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies	36
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair	36
Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways	36
Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity	35
The role of R-spondin proteins in cancer biology	35
Genome-wide CRISPR-cas9 knockout screening identifies GRB7 as a driver for MEK inhibitor resistance in KRAS mutant colon cancer	35
Alterations of T-cell-mediated immunity in acute myeloid leukemia	35
Therapeutic targeting of the mitochondrial one-carbon pathway: perspectives, pitfalls, and potential	35
FGF19 and FGFR4 promotes the progression of gallbladder carcinoma in an autocrine pathway dependent on GPBAR1-cAMP-EGR1 axis	35
Lipogenic signalling modulates prostate cancer cell adhesion and migration via modification of Rho GTPases	34
Metabolic reprogramming of ovarian cancer involves ACSL1-mediated metastasis stimulation through upregulated protein myristoylation	34
YAP1 overexpression contributes to the development of enzalutamide resistance by induction of cancer stemness and lipid metabolism in prostate cancer	34
Lymph node metastasis-derived gastric cancer cells educate bone marrow-derived mesenchymal stem cells via YAP signaling activation by exosomal Wnt5a	34
Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance	34
Phosphorylation of BCKDK of BCAA catabolism at Y246 by Src promotes metastasis of colorectal cancer	34
The oxytocin receptor signalling system and breast cancer: a critical review	34
Gastric cancer: genome damaged by bugs	34
Long noncoding RNA CMPK2 promotes colorectal cancer progression by activating the FUBP3–c-Myc axis	33
HDAC8 promotes the dissemination of breast cancer cells via AKT/GSK-3β/Snail signals	33
Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT	33
RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing	33
CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model	33
Tenascin C promotes cancer cell plasticity in mesenchymal glioblastoma	32
How artificial intelligence might disrupt diagnostics in hematology in the near future	32
Targeting mTOR signaling overcomes acquired resistance to combined BRAF and MEK inhibition in BRAF-mutant melanoma	32

Tumor-derived osteopontin drives the resident fibroblast to myofibroblast differentiation through Twist1 to promote breast cancer progression	32
The proprotein convertase furin is a pro-oncogenic driver in KRAS and BRAF driven colorectal cancer	32
Hexosamine pathway inhibition overcomes pancreatic cancer resistance to gemcitabine through unfolded protein response and EGFR-Akt pathway modulation	32
KNSTRN promotes tumorigenesis and gemcitabine resistance by activating AKT in bladder cancer	32
Transcription factors in colorectal cancer: molecular mechanism and therapeutic implications	32
FOXO3a-driven miRNA signatures suppresses VEGF-A/NRP1 signaling and breast cancer metastasis	32
SP1-activated long noncoding RNA lncRNA GCMA functions as a competing endogenous RNA to promote tumor metastasis by sponging miR-124 and miR-34a in gastric cancer	32
POLE, POLD1, and NTHL1: the last but not the least hereditary cancer-predisposing genes	32
Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis	31
A dysbiotic microbiome promotes head and neck squamous cell carcinoma	31
CTHRC1 promotes liver metastasis by reshaping infiltrated macrophages through physical interactions with TGF-β receptors in colorectal cancer	31
Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling	31
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer	31
ZNF750 represses breast cancer invasion via epigenetic control of prometastatic genes	31
Polyploid giant cancer cells, stemness and epithelial-mesenchymal plasticity elicited by human cytomegalovirus	30
AMOTL1 enhances YAP1 stability and promotes YAP1-driven gastric oncogenesis	30
LINC00467 is up-regulated by TDG-mediated acetylation in non-small cell lung cancer and promotes tumor progression	30
SIX4 promotes hepatocellular carcinoma metastasis through upregulating YAP1 and c-MET	30
N6-methyladenosine demethylase ALKBH5 suppresses malignancy of esophageal cancer by regulating microRNA biogenesis and RAI1 expression	30
CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway	30
Exosomal miR-4466 from nicotine-activated neutrophils promotes tumor cell stemness and metabolism in lung cancer metastasis	30
Extracellular ATP promotes breast cancer invasion and chemoresistance via SOX9 signaling	30
The ER stress response mediator ERO1 triggers cancer metastasis by favoring the angiogenic switch in hypoxic conditions	30
RETRACTED ARTICLE: HBx/ERα complex-mediated LINC01352 downregulation promotes HBV-related hepatocellular carcinoma via the miR-135b-APC axis	29
Oroxylin A reverses hypoxia-induced cisplatin resistance through inhibiting HIF-1α mediated XPC transcription	29
NK and NKT cells have distinct properties and functions in cancer	29
Molecular biological analysis of 5-FU-resistant gastric cancer organoids; KHDRBS3 contributes to the attainment of features of cancer stem cell	29
Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice	29
POU1F1 transcription factor induces metabolic reprogramming and breast cancer progression via LDHA regulation	29
Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges	29
SOX4 activates CXCL12 in hepatocellular carcinoma cells to modulate endothelial cell migration and angiogenesis in vivo	29
Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians	29
CTGF regulates cell proliferation, migration, and glucose metabolism through activation of FAK signaling in triple-negative breast cancer	29
EphA2–YES1–ANXA2 pathway promotes gastric cancer progression and metastasis	29
Small non-coding RNAs in human cancer: function, clinical utility, and characterization	29
SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer	29
YTHDF2 is a potential target of AML1/ETO-HIF1α loop-mediated cell proliferation in t(8;21) AML	29
SIRT7 activates p53 by enhancing PCAF-mediated MDM2 degradation to arrest the cell cycle	28
Spontaneous and inherited TP53 genetic alterations	28
Wild-type isocitrate dehydrogenase under the spotlight in glioblastoma	28
Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p53	28
CD73 induces GM-CSF/MDSC-mediated suppression of T cells to accelerate pancreatic cancer pathogenesis	28
EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair	28
The HSF1/miR-135b-5p axis induces protective autophagy to promote oxaliplatin resistance through the MUL1/ULK1 pathway in colorectal cancer	28
Oncogenic Smurf1 promotes PTEN wild-type glioblastoma growth by mediating PTEN ubiquitylation	28
EGFR activity addiction facilitates anti-ERBB based combination treatment of squamous bladder cancer	28
NSD2 promotes tumor angiogenesis through methylating and activating STAT3 protein	28
NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration	28
Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer	27
Oct4 confers stemness and radioresistance to head and neck squamous cell carcinoma by regulating the homologous recombination factors PSMC3IP and RAD54L	27
Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer	27
LncRNA GAL promotes colorectal cancer liver metastasis through stabilizing GLUT1	27
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma	27
Radiation-induced YAP activation confers glioma radioresistance via promoting FGF2 transcription and DNA damage repair	27
The m6A reading protein YTHDF3 potentiates tumorigenicity of cancer stem-like cells in ocular melanoma through facilitating CTNNB1 translation	27
Aberrant activation of super enhancer and choline metabolism drive antiandrogen therapy resistance in prostate cancer	27
αSMA+ fibroblasts suppress Lgr5+ cancer stem cells and restrain colorectal cancer progression	27
Cell-type deconvolution analysis identifies cancer-associated myofibroblast component as a poor prognostic factor in multiple cancer types	27
M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression	27
The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer	27
DNA methylome profiling of circulating tumor cells in lung cancer at single base-pair resolution	27
p53 partial loss-of-function mutations sensitize to chemotherapy	26
Dexamethasone enhances the lung metastasis of breast cancer via a PI3K-SGK1-CTGF pathway	26
S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK1	26
microRNA-93-5p promotes hepatocellular carcinoma progression via a microRNA-93-5p/MAP3K2/c-Jun positive feedback circuit	26
Single-cell EMT-related transcriptional analysis revealed intra-cluster heterogeneity of tumor cell clusters in epithelial ovarian cancer ascites	26
Functional genomics identifies new synergistic therapies for retinoblastoma	26
ST6Gal1 targets the ectodomain of ErbB2 in a site-specific manner and regulates gastric cancer cell sensitivity to trastuzumab	26
Comprehensive characterisation of intronic mis-splicing mutations in human cancers	26
Pharmacologic conversion of cancer-associated fibroblasts from a protumor phenotype to an antitumor phenotype improves the sensitivity of pancreatic cancer to chemotherapeutics	26
HuR up-regulates cell surface PD-L1 via stabilizing CMTM6 transcript in cancer	26
MCU-dependent negative sorting of miR-4488 to extracellular vesicles enhances angiogenesis and promotes breast cancer metastatic colonization	26
FGF18–FGFR2 signaling triggers the activation of c-Jun–YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential	26
MicroRNA determinants of neuroendocrine differentiation in metastatic castration-resistant prostate cancer	26
BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors	26
O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation	26
Modulation of DNA double-strand break repair as a strategy to improve precise genome editing	26
Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer	25
MYEOV increases HES1 expression and promotes pancreatic cancer progression by enhancing SOX9 transactivity	25
Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF4	25
Epiregulin confers EGFR-TKI resistance via EGFR/ErbB2 heterodimer in non-small cell lung cancer	25
Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS	25
Recent advances in preclinical models for lung squamous cell carcinoma	25
Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC	25
Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene	25
Positive feedback regulation of lncRNA PVT1 and HIF2α contributes to clear cell renal cell carcinoma tumorigenesis and metastasis	25
IGF1R acts as a cancer-promoting factor in the tumor microenvironment facilitating lung metastasis implantation and progression	25
Plectin is a regulator of prostate cancer growth and metastasis	24
A detailed characterization of stepwise activation of the androgen receptor variant 7 in prostate cancer cells	24
The CUL4B-miR-372/373-PIK3CA-AKT axis regulates metastasis in bladder cancer	24
STING protects breast cancer cells from intrinsic and genotoxic-induced DNA instability via a non-canonical, cell-autonomous pathway	24
Melatonin interrupts osteoclast functioning and suppresses tumor-secreted RANKL expression: implications for bone metastases	24
CBX7 binds the E-box to inhibit TWIST-1 function and inhibit tumorigenicity and metastatic potential	24
Exome sequencing identifies ARID2 as a novel tumor suppressor in early-onset sporadic rectal cancer	24
Malignant peripheral nerve sheath tumor: models, biology, and translation	24