OOIR: Observatory of International Research

Papers

(The H4-Index of Oncogene is 52. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Identification of novel germline mutations in FUT7 and EXT1 linked with hereditary multiple exostoses	183
SOX10 deficiency-mediated LAMB3 upregulation determines the invasiveness of MAPKi-resistant melanoma	153
Correction: Regulation of cancer stem cell activity by thyroid hormone receptor β	149
Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells	134
Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts	133
Deciphering glioma epitranscriptome: focus on RNA modifications	129
USP5 deubiquitinates and stabilizes IMPDH2, to promote hepatocellular carcinoma progression	109
Correction: S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia	108
Correction to: Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential	105
Structure and function of MuvB complexes	104
SKAP2 suppresses inflammation-mediated tumorigenesis by regulating SHP-1 and SHP-2	102
RBMS3-loss impedes TRIM21-induced ubiquitination of ANGPT2 in an RNA-independent manner and drives sorafenib resistance in hepatocellular carcinoma	101
Correction: Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer	93
A comprehensive analysis of LMO2 pathogenic regulatory profile during T-lineage development and leukemic transformation	87
The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis	86
Correction: Targeting the HIF-1α-IGFBP2 axis therapeutically reduces IGF1-AKT signaling and blocks the growth and metastasis of relapsed anaplastic Wilms tumor	84
LIGHT enhanced bispecific antibody armed T-cells to treat immunotherapy resistant colon cancer	81
AMPK-deficiency forces metformin-challenged cancer cells to switch from carbohydrate metabolism to ketogenesis to support energy metabolism	80
SCD5-dependent inhibition of SPARC secretion hampers metastatic spreading and favors host immunity in a TNBC murine model	80
Correction: SOX18 promotes gastric cancer metastasis through transactivating MCAM and CCL7	73
Retraction Note: CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells	72
Gamma-glutamyltransferase 7 suppresses gastric cancer by cooperating with RAB7 to induce mitophagy	71
A novel amplification gene PCI domain containing 2 (PCID2) promotes colorectal cancer through directly degrading a tumor suppressor promyelocytic leukemia (PML)	70
Spatiotemporal view of malignant histogenesis and macroevolution via formation of polyploid giant cancer cells	70
Trop-2, Na+/K+ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion	69

Nup54-induced CARM1 nuclear importation promotes gastric cancer cell proliferation and tumorigenesis through transcriptional activation and methylation of Notch2	68
MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex	66
Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks	65
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer	65
MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells	63
GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation	63
Notch signaling regulates a metabolic switch through inhibiting PGC-1α and mitochondrial biogenesis in dedifferentiated liposarcoma	63
Hypoxia induces chemoresistance to proteasome inhibitors through orchestrating deSUMOylation and ubiquitination of SRC-3 in multiple myeloma	62
Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity	62
tRF-33-P4R8YP9LON4VDP inhibits gastric cancer progression via modulating STAT3 signaling pathway in an AGO2-dependent manner	61
YTHDF2 is a potential target of AML1/ETO-HIF1α loop-mediated cell proliferation in t(8;21) AML	61
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin	60
METTL3-mediated N6-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF4	59
ALDH1A3 is the switch that determines the balance of ALDH+ and CD24−CD44+ cancer stem cells, EMT-MET, and glucose metabolism in breast cancer	59
LncRNA XIST regulates breast cancer stem cells by activating proinflammatory IL-6/STAT3 signaling	58
BTLA+CD200+ B cells dictate the divergent immune landscape and immunotherapeutic resistance in metastatic vs. primary pancreatic cancer	58
Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma	58
H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth	56
Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis	56
ANKFN1 plays both protumorigenic and metastatic roles in hepatocellular carcinoma	56
Single-cell multiomics reveals a gene regulatory circuit driving leukemia cell differentiation	55
Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis	54
MASTL regulates EGFR signaling to impact pancreatic cancer progression	54
CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of β-catenin	54
Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF263	53
The protection of UCK2 protein stability by GART maintains pyrimidine salvage synthesis for HCC growth under glucose limitation	53
Crosstalk between endothelial progenitor cells and HCC through periostin/CCL2/CD36 supports formation of the pro-metastatic microenvironment in HCC	52