OOIR: Observatory of International Research

Papers

(The H4-Index of Oncogene is 52. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
A risk model developed based on tumor microenvironment predicts overall survival and associates with tumor immunity of patients with lung adenocarcinoma	151
A novel hypoxic long noncoding RNA KB-1980E6.3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability	144
The functional roles of TCA cycle metabolites in cancer	138
Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations	131
Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines	125
Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity	118
Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivo	110
HGF/c-MET pathway in cancer: from molecular characterization to clinical evidence	105
HDAC inhibition potentiates anti-tumor activity of macrophages and enhances anti-PD-L1-mediated tumor suppression	98
CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1	96
Receptor tyrosine kinases and cancer: oncogenic mechanisms and therapeutic approaches	96
FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis	91
Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma	90
STAT3 phosphorylation at Ser727 and Tyr705 differentially regulates the EMT–MET switch and cancer metastasis	88
Counteracting CAR T cell dysfunction	87
Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer	83
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy	82
Hypoxic exosomal HIF-1α-stabilizing circZNF91 promotes chemoresistance of normoxic pancreatic cancer cells via enhancing glycolysis	81
Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy	79
Loss and revival of androgen receptor signaling in advanced prostate cancer	78
NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization	76
Understanding the role of integrins in breast cancer invasion, metastasis, angiogenesis, and drug resistance	73
RETRACTED ARTICLE: MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer	71
Oncogenic functions and therapeutic targeting of EphA2 in cancer	70
Plasma exosomes from endometrial cancer patients contain LGALS3BP to promote endometrial cancer progression	68

Partial EMT in head and neck cancer biology: a spectrum instead of a switch	68
ROS production by mitochondria: function or dysfunction?	68
Is PD-L1 a consistent biomarker for anti-PD-1 therapy? The model of balstilimab in a virally-driven tumor	66
Spatial collagen stiffening promotes collective breast cancer cell invasion by reinforcing extracellular matrix alignment	66
N7-methylguanosine tRNA modification promotes tumorigenesis and chemoresistance through WNT/β-catenin pathway in nasopharyngeal carcinoma	66
The role of MET in chemotherapy resistance	62
Role of p38 MAP kinase in cancer stem cells and metastasis	62
Turning up the heat on non-immunoreactive tumors: pyroptosis influences the tumor immune microenvironment in bladder cancer	62
Nerve fibers in the tumor microenvironment in neurotropic cancer—pancreatic cancer and cholangiocarcinoma	61
LncRNA MIR17HG promotes colorectal cancer liver metastasis by mediating a glycolysis-associated positive feedback circuit	60
A highly annotated database of genes associated with platinum resistance in cancer	60
DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway	60
Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions	59
A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination	59
VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk	59
METTL3-mediated m6A methylation of SPHK2 promotes gastric cancer progression by targeting KLF2	58
METTL3 promotes intrahepatic cholangiocarcinoma progression by regulating IFIT2 expression in an m6A-YTHDF2-dependent manner	58
The role of natural killer cell in gastrointestinal cancer: killer or helper	57
CircHIF1A regulated by FUS accelerates triple-negative breast cancer progression by modulating NFIB expression and translocation	56
Parvimonas micra promotes colorectal tumorigenesis and is associated with prognosis of colorectal cancer patients	56
MAOA promotes prostate cancer cell perineural invasion through SEMA3C/PlexinA2/NRP1–cMET signaling	56
The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2	54
Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand	54
CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer	53
COL11A1 activates cancer-associated fibroblasts by modulating TGF-β3 through the NF-κB/IGFBP2 axis in ovarian cancer cells	53
CD8+ T effector and immune checkpoint signatures predict prognosis and responsiveness to immunotherapy in bladder cancer	53
Supercharging BRD4 with NUT in carcinoma	53