Development

Article	Citations
The people behind the papers – Ya Min, Stephanie Conway and Elena Kramer	111
Harnessing developmental cues for cardiomyocyte production	102
Zasp52 strengthens whole embryo tissue integrity through supracellular actomyosin networks	95
Abscisic acid biosynthesis is necessary for full auxin effects on hypocotyl elongation	90
Alignment of the cell long axis by unidirectional tension acts cooperatively with Wnt signalling to establish planar cell polarity	77
MIG-23 is involved in sperm migration by modulating extracellular ATP levels in Ascaris suum	73
The Forest of Biologists – for biologists, for biology	70
Local protein synthesis of neuronal MT1-MMP for agrin-induced presynaptic development	69
Patterning on the move: the effects of Hh morphogen source movement on signaling dynamics	68
A low-sugar diet enhancesDrosophilabody size in males and females via sex-specific mechanisms	67
Csf1rb regulates definitive hematopoiesis in zebrafish	66
The people behind the papers – Jake Turley	64
The Excursion	60
Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken	59
The AKT1-FOXO4 axis reciprocally regulates hemochorial placentation	57
Ernest Arenas (1962-2024): a legacy of advancing dopaminergic neurogenesis research	57
hnRNPH1 establishes Sertoli–germ cell crosstalk through cooperation with PTBP1 and AR, and is essential for male fertility in mice	57
Defective mesothelium and limited physical space are drivers of dysregulated lung development in a genetic model of congenital diaphragmatic hernia	54
The functional specificity of ERECTA-family receptors in Arabidopsis stomatal development is ensured by molecular chaperones in the endoplasmic reticulum	52
Normal cell cycle progression requires negative regulation of E2F1 by Groucho during S phase and its relief at G2 phase	51
Biased precursor ingression underlies the center-to-pole pattern of male sex determination in mouse	51
The people behind the papers – Kelsey Brooks and Shawn Chavez	50
Correction: Wt1 transcription factor impairs cardiomyocyte specification and drives a phenotypic switch from myocardium to epicardium	49
In preprints: new insights into truncated radial glia	48
PHLPP1 regulates CFTR activity and lumen expansion through AMPK	42

Cdkn1c orchestrates a molecular network that regulates euploidy of male mouse germline stem cells	41
Cadherin adhesion complexes direct cell aggregation in the epithelial transition of Wnt-induced nephron progenitor cells	40
HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples	40
Shared cis-regulatory modules control expression of the tandem paralogs midline and H15 in the follicular epithelium	39
Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427	38
Destabilisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation	38
Approaches to benchmark and characterize in vitro human model systems	37
Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm	37
Testosterone acts through the membrane protein GPRC6A to cause cardiac edema in zebrafish embryos	35
Ccn2a-FGFR1-SHH signaling is necessary for intervertebral disc homeostasis and regeneration in adult zebrafish	35
Drosophilaembryos spatially sort their nutrient stores to facilitate their utilization	35
Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter	35
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease	35
FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton	35
The role of O-GlcNAcylation in development	34
A new cell culture resource for investigations of reptilian gene function	34
Live imaging of adult zebrafish cardiomyocyte proliferation ex vivo	33
Notch-dependent DNAcis-regulatory elements and their dose-dependent control ofC. elegansstem cell self-renewal	32
Quantitative videomicroscopy reveals latent control of cell-pair rotations in vivo	31
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain	31
The genetic basis of natural variation in the timing of vegetative phase change inArabidopsis thaliana	31
The combined action of Esrrb and Nr5a2 is essential for murine naïve pluripotency	31
Cerebellum lineage allocation, morphogenesis and repair: impact of interplay amongst cells	30
Pten inhibition dedifferentiates long-distance axon-regenerating intrinsically photosensitive retinal ganglion cells and upregulates mitochondria-associated Dynlt1a and Lars2	30
Nutritional control of developmental processes	30
The people behind the papers – Julia Grzymkowski and Nanette Nascone-Yoder	29
Identification of disease-relevant modulators of the SHH pathway in the developing brain	29
The extra-embryonic area opaca plays a role in positioning the primitive streak of the early chick embryo	29
The impact of cell size on morphogen gradient precision	29
Transitions in development – an interview with Peng Du	29
PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes	29
Real-time monitoring of an endogenous Fgf8a gradient attests to its role as a morphogen during zebrafish gastrulation	29
SOX2 transcription factor binding and function	29
Transitions in development – an interview with Thibaut Brunet	29
PFN4 is required for manchette development and acrosome biogenesis during mouse spermiogenesis	29
PBAF chromatin remodeler complexes that mediate meiotic transitions in mouse	29
Prostate organogenesis	28
The H2Bub1-deposition complex is required for human and mouse cardiogenesis	28
Maf family transcription factors are required for nutrient uptake in the mouse neonatal gut	27
Microgel culture and spatial identity mapping elucidate the signalling requirements for primate epiblast and amnion formation	27
The people behind the papers – Yongjun Yin and David Ornitz	27
The insulator BEAF32 controls the spatial-temporal expression profile of the telomeric retrotransposon TART in the Drosophila germline	27
Parallels between oncogene-driven cardiac hyperplasia and heart regeneration in zebrafish	27
In preprints: shrinking boundary cells reveal fluid flux in organogenesis	27
Modeling mammalian spermatogonial differentiation and meiotic initiationin vitro	27
An interview with Scott Fraser	26
Sequential and additive expression of miR-9 precursors control timing of neurogenesis	26
In preprints: new insights into root stem cells and their diversity	26
The Blimp-1 transcription factor acts in non-neuronal cells to regulate terminal differentiation of the Drosophila eye	26
In preprints: shaping the developing human brain	26

Transitions in development – an interview with Antonio Scialdone	26
mBeRFP: a versatile fluorescent tool to enhance multichannel live imaging and its applications	26
Multi-view confocal microscopy enables multiple organ and whole organism live-imaging	26
Single-cell reconstruction with spatial context of migrating neural crest cells and their microenvironments during vertebrate head and neck formation	26
A lissencephaly-associated BAIAP2 variant causes defects in neuronal migration during brain development	26
Wnt7b expressed by hypertrophic chondrocytes is a stimulatory factor for endochondral ossification that is regulated by Smad4 activity	26
Insights into the role of immune cells in development and regeneration	25
rasa1-related arteriovenous malformation is driven by aberrant venous signalling	25
Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development	25
Krüppel-like factor gene function in the ctenophore Mnemiopsis leidyi assessed by CRISPR/Cas9-mediated genome editing	25
The ERM-1 membrane-binding domain directs erm-1 mRNA localization to the plasma membrane in the C. elegans embryo	25
Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure	25
Single-cell genomics revolutionizes plant development studies across scales	25
Ribosome biogenesis and function in development and disease	25
Destabilization of mRNAs enhances competence to initiate meiosis in mouse spermatogenic cells	25
New wave theory	24
Hemocytes are essential for Drosophila melanogaster post-embryonic development, independent of control of the microbiota	24
Signalling pathway crosstalk stimulated by L-proline drives mouse embryonic stem cells to primitive-ectoderm-like cells	24
Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects	24
The people behind the papers – Vahid Zadmajid and Daniel Gorelick	24
Contribution of vasculature to stem integrity in Arabidopsis thaliana	24
Intrinsic positional memory guides target-specific axon regeneration in the zebrafish vagus nerve	24
The chromatin source-sink hypothesis: a shared mode of chromatin-mediated regulations	24
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology	24
The people behind the papers – Alyshia Scholl, Yihong Liu and Geraldine Seydoux	23
A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body	23
Advancing stem cell technologies for conservation of wildlife biodiversity	23
Traip controls mushroom body size by suppressing mitotic defects	23
Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle	23
Anatomy and development of the pectoral fin vascular network in the zebrafish	23
Pleiotropy of autism-associated chromatin regulators	23
The people behind the papers – Alfahdah Alsudayri and Lihua Ye	22
Celsr1 suppresses Wnt5a-mediated chemoattraction to prevent incorrect rostral migration of facial branchiomotor neurons	22
An in vivo CRISPR screen in chick embryos reveals a role for MLLT3 in specification of neural cells from the caudal epiblast	22
FGF signaling acts on different levels of mesoderm development within Spiralia	22
Microglia refine developing retinal astrocytic and vascular networks through the complement C3/C3aR axis	22
The people behind the papers – Emily Bulger and Benoit Bruneau	22
Keeping up with the Node	22
Srsf3 mediates alternative RNA splicing downstream of PDGFRα signaling in the facial mesenchyme	22
Oxygen-sensing mechanisms in development and tissue repair	21
Stable establishment of organ polarity occurs several plastochrons before primordium outgrowth in Arabidopsis	21
Single-cell transcriptomics identifies new blood cell populations in Drosophila released at the onset of metamorphosis	21
Hydrostatic mechanical stress regulates growth and maturation of the atrioventricular valve	21
GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism	21
The MEK-ERK signaling pathway promotes maintenance of cardiac chamber identity	21
Hindbrain boundaries as niches of neural progenitor and stem cells regulated by the extracellular matrix proteoglycan chondroitin sulphate	21
Cell division angle predicts the level of tissue mechanics that tune the amount of cerebellar folding	21
Dynamic de novo adipose tissue development during metamorphosis in Drosophila melanogaster	20
Normal Table of Xenopus development: a new graphical resource	20
Transitions in development – an interview with Salah Elias	20
Disruption of placental ACKR3 impairs growth and hematopoietic development of offspring	20
A transit-amplifying progenitor with biphasic behavior contributes to epidermal renewal	20
The Hox code responsible for the patterning of the anterior vertebrae in zebrafish	20
VitelloTag: a tool for high-throughput cargo delivery into oocytes	20
Transitions in development – an interview with Daniel Ríos Barrera	20
The histone demethylase PHF8 regulates astrocyte differentiation and function	20
Cell-cell communication through FGF4 generates and maintains robust proportions of differentiated cell types in embryonic stem cells	20
Cell-type-specific interacting proteins collaborate to regulate the timing of Cyclin B protein expression in male meiotic prophase	20
Correction: Zebrafish dazl regulates cystogenesis and germline stem cell specification during the primordial germ cell to germline stem cell transition	20
Unlocking the potential of SY-stem cells	19
Cranium growth, patterning and homeostasis	19
Epha1 is a cell-surface marker for the neuromesodermal competent population	19
Single-minded 2 is required for left-right asymmetric stomach morphogenesis	19
Tubb4b is required for multi-ciliogenesis in the mouse	19
The people behind the papers – Juan Yang and Xuanmao Chen	19
Transitions in development – an interview with Kara McKinley	19
Quantitative live imaging of floral organ initiation and floral meristem termination in Aquilegia	19
Excess dietary sugar impairs Drosophila adult stem cells via elevated reactive oxygen species-induced JNK signaling	19
Drosophila CTP synthase regulates collective cell migration by controlling the polarized endocytic cycle	19
FOXP4 differentially controls cold-induced beige adipocyte differentiation and thermogenesis	19
Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons	19
Tissue-specific RNA-seq defines genes governing male tail tip morphogenesis in C. elegans	19
The people behind the papers – Dennis de Bakker, Mara Bouwman and Jeroen Bakkers	19
Development's 2023 Outstanding Paper Prize	19
Elevated numbers of infiltrating eosinophils accelerate the progression of Duchenne muscular dystrophy pathology in mdx mice	19
The dynamics of tubulogenesis in development and disease	18
Different temporal requirements for tartan and wingless in the formation of contractile interfaces at compartmental boundaries	18
The brain on time: links between development and neurodegeneration	18
An inducible germ cell ablation chicken model for high-grade germline chimeras	18
FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice	18

Direct force measurement and loading on developing tissues in intact avian embryos	18
Msl3 promotes germline stem cell differentiation in female Drosophila	18
Pathway to Independence – an interview with Clémentine Villeneuve	18
Direct repression of Nanog and Oct4 by OTX2 modulates the contribution of epiblast-derived cells to germline and somatic lineage	18
Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion	18
In preprints: lifetime changes in leaf shape	18
Conserved roles of ETT and ARF4 in gynoecium development in Brassicaceae with distinct fruit shapes	18
E93 is indispensable for reproduction in ametabolous and hemimetabolous insects	18
Wnt9 directs zebrafish heart tube assembly via a combination of canonical and non-canonical pathway signaling	18
Correction: Transcriptional dynamics during karyogamy in rice zygotes	18
Confinement promotes nematic alignment of spindle-shaped cells during Drosophila embryogenesis	18
Transitions in development – an interview with Evgeny Kvon	18
Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways	18
A comparative analysis of TonEBP conditional knockout mouse models reveals inter-dependency between compartments of the intervertebral disc	18
Lineage-based scaling of germline intercellular bridges during oogenesis	18
Loss of perinuclear theca ACTRT1 causes acrosome detachment and severe male subfertility in mice	18
Compensation of gene dosage on the mammalian X	17
osr1couples intermediate mesoderm cell fate with temporal dynamics of vessel progenitor cell differentiation	17
New year, new developments: a look back and a look ahead	17
Mammalian DNA methylome dynamics: mechanisms, functions and new frontiers	17
Suppression of YAP safeguards human naïve pluripotency	17
Pivotal role of STIP in ovule pattern formation and female germline development in Arabidopsis thaliana	17
In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary	17
Multiple cis-regulatory elements control prox1a expression in distinct lymphatic vascular beds	17
Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip1	17
LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation	17
Pathway to Independence – an interview with Marcella Birtele	17
Reduction of cortical parvalbumin-expressing GABAergic interneurons in a rodent hyperoxia model of preterm birth brain injury with deficits in social behavior and cognition	17
Duplicated antagonistic EPF peptides optimize grass stomatal initiation	17
Interaction of Gαi2 with EB1 controls microtubule dynamics and Rac1 activity in Xenopus neural crest cell migration	17
BET activity plays an essential role in control of stem cell attributes in Xenopus	17
regeneration factors expressed on myeloid expression in macrophage-like cells is required for tail regeneration in Xenopus laevis tadpoles	16
A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals	16
Dissecting pleiotropic functions of the wheat Green Revolution gene Rht-B1b in plant morphogenesis and yield formation	16
Motor neurons in the tunicate caudal central nervous system reveal homology to the vertebrate spinal cord	16
De novo PAM generation to reach initially inaccessible target sites for base editing	16
Gibberellin and miRNA156-targeted SlSBP genes synergistically regulate tomato floral meristem determinacy and ovary patterning	16
The exocyst complex regulates C. elegans germline stem cell proliferation by controlling membrane Notch levels	16
PUF-8, a C. elegans ortholog of the RNA-binding proteins PUM1 and PUM2, is required for robustness of the cell death fate	16
A renaissance for developmental biology driven by new in vitro platforms	16
Orb-dependent polyadenylation contributes to PLP expression and centrosome scaffold assembly	16
Environmental and molecular control of tissue-specific ionocyte differentiation in zebrafish	16
Control of fate specification within the dorsal head of Drosophila melanogaster	16
Exploring the principles of embryonic mammary gland branching morphogenesis	16
The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance	16
Expanding the evo-devo toolkit: generation of 3D mammary tissue from diverse mammals	16
An ancient testis-specific IQ motif-containing H gene regulates specific transcript isoform expression during spermatogenesis	16
Transplanted human intestinal organoids: a resource for modeling human intestinal development	16
The miR156 juvenility factor and PLETHORA 2 form a regulatory network and influence timing of meristem growth and lateral root emergence	16
IL7Rα, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells	16
Cre recombinase microinjection for single-cell tracing and localised gene targeting	16
The cellular function of ROP GTPase prenylation is important for multicellularity in the moss Physcomitrium patens	16
An end-to-end pipeline based on open source deep learning tools for reliable analysis of complex 3D images of ovaries	16
PLETHORA transcription factors promote early embryo development through induction of meristematic potential	15
NHR-23 activity is necessary for C. elegans developmental progression and apical extracellular matrix structure and function	15
A constitutively expressed fluorescent ubiquitination-based cell-cycle indicator (FUCCI) in axolotls for studying tissue regeneration	15
The people behind the papers – Masaki Kinoshita, Toshihiro Kobayashi, Hiroshi Nagashima, Ramiro Alberio and Austin Smith	15
Transitions in development – an interview with Amy Shyer and Alan Rodrigues	15
Induced regeneration of articular cartilage – identification of a dormant regeneration program for a non-regenerative tissue	15
H4K20me3 marks distal intergenic and repetitive regions in human mature spermatozoa	15
Sculpting with stem cells: how models of embryo development take shape	15
The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis	15
Enhancer RNAs step forward: new insights into enhancer function	15
Cyclical endometrial repair and regeneration	15
The people behind the papers – Masahito Irie, Fumitoshi Ishino and Tomoko Kaneko-Ishino	15
Y box-binding protein 1 regulates zebrafish folliculogenesis partly through p21-mediated control of follicle cell proliferation	15
An elastic proteinaceous envelope encapsulates the early Arabidopsis embryo	15
Immune cell-stem cell interactions in regeneration and repair: who's calling the shots?	15
Adipose triglyceride lipase promotes prostaglandin-dependent actin remodeling by regulating substrate release from lipid droplets	15
Evolution of the regulation of developmental gene expression in blind Mexican cavefish	15
Development of the mammalian main olfactory bulb	15
A high-sugar diet, but not obesity, reduces female fertility in Drosophila melanogaster	15
The class VIII myosin ATM1 is required for root apical meristem function	15
A method for stabilising the XX karyotype in female mESC cultures	15
Live imaging of retinotectal mapping reveals topographic map dynamics and a previously undescribed role for Contactin 2 in map sharpening	15
Correction: A single-plasmid approach for genome editing coupled with long-term lineage analysis in chick embryos	15
Intercellular contact and cargo transfer between Müller glia and to microglia precede apoptotic cell clearance in the developing retina	14
Human developmental biology – a global perspective	14
Progression of the pluripotent epiblast depends upon the NMD factor UPF2	14
Human stem cell models to study placode development, function and pathology	14
Gut microbiota regulate maturation and mitochondrial function of the nutrient-sensing enteroendocrine cell	14
Female meiosis II and pronuclear fusion require the microtubule transport factor Bicaudal D	14
TAF4b transcription networks regulating early oocyte differentiation	14
Differential proliferation regulates multi-tissue morphogenesis during embryonic axial extension: integrating viscous modeling and experimental approaches	14
Defining the Hoxb8 cell lineage during murine definitive hematopoiesis	14
Thymic epithelial organoids mediate T-cell development	14
The people behind the papers – Wendy Duan and Meghan Riddell	14
The Nasonia pair-rule gene regulatory network retains its function over 300 million years of evolution	14
Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes	14
Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF	14
Collective signalling drives rapid jumping between cell states	14
A Rad50-null mutation in mouse germ cells causes reduced DSB formation, abnormal DSB end resection and complete loss of germ cells	14
The matrix glycoprotein Papilin maintains the haematopoietic progenitor pool in Drosophila lymph glands	14
Adaxial-abaxial bipolar leaf genes encode a putative cytokinin receptor and HD-Zip III, and control the formation of ectopic shoot meristems in rice	14
Cell state transitions: catch them if you can	14