Development

Article	Citations
The people behind the papers – Yanmei Tao and Zhengdong Wei	125
The AKT1-FOXO4 axis reciprocally regulates hemochorial placentation	111
Normal cell cycle progression requires negative regulation of E2F1 by Groucho during S phase and its relief at G2 phase	88
Live imaging of adult zebrafish cardiomyocyte proliferation ex vivo	84
MIG-23 is involved in sperm migration by modulating extracellular ATP levels in Ascaris suum	82
The people behind the papers – Stanley Strawbridge	79
Ccn2a-FGFR1-SHH signaling is necessary for intervertebral disc homeostasis and regeneration in adult zebrafish	78
Cdkn1c orchestrates a molecular network that regulates euploidy of male mouse germline stem cells	77
Patterning on the move: the effects of Hh morphogen source movement on signaling dynamics	71
Notch-dependent DNAcis-regulatory elements and their dose-dependent control ofC. elegansstem cell self-renewal	69
Correction: Wt1 transcription factor impairs cardiomyocyte specification and drives a phenotypic switch from myocardium to epicardium	68
Shared cis-regulatory modules control expression of the tandem paralogs midline and H15 in the follicular epithelium	67
The people behind the papers – Ya Min, Stephanie Conway and Elena Kramer	65
In preprints: retinoic acid degradation and tissue stiffness coordinate axolotl limb regeneration	64
The people behind the papers – Kelsey Brooks and Shawn Chavez	58
Harnessing developmental cues for cardiomyocyte production	57
Pten inhibition dedifferentiates long-distance axon-regenerating intrinsically photosensitive retinal ganglion cells and upregulates mitochondria-associated Dynlt1a and Lars2	57
In preprints: new insights into truncated radial glia	54
Alignment of the cell long axis by unidirectional tension acts cooperatively with Wnt signalling to establish planar cell polarity	47
The people behind the papers – Jake Turley	46
The Forest of Biologists – for biologists, for biology	45
A new cell culture resource for investigations of reptilian gene function	44
PHLPP1 regulates CFTR activity and lumen expansion through AMPK	44
Ernest Arenas (1962-2024): a legacy of advancing dopaminergic neurogenesis research	43
Destabilisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation	43

Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427	43
Nutritional control of developmental processes	42
The genetic basis of natural variation in the timing of vegetative phase change inArabidopsis thaliana	41
Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter	39
Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken	39
Biased precursor ingression underlies the center-to-pole pattern of male sex determination in mouse	38
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease	37
Approaches to benchmark and characterize in vitro human model systems	36
Drosophilaembryos spatially sort their nutrient stores to facilitate their utilization	36
Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm	36
A low-sugar diet enhancesDrosophilabody size in males and females via sex-specific mechanisms	36
The Excursion	36
Csf1rb regulates definitive hematopoiesis in zebrafish	35
The role of O-GlcNAcylation in development	33
Quantitative videomicroscopy reveals latent control of cell-pair rotations in vivo	33
hnRNPH1 establishes Sertoli–germ cell crosstalk through cooperation with PTBP1 and AR, and is essential for male fertility in mice	33
Cerebellum lineage allocation, morphogenesis and repair: impact of interplay amongst cells	33
Adhesion strength, cell packing density and cell surface buckling in pericellular matrix-mediated tissue cohesion	32
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain	32
The combined action of Esrrb and Nr5a2 is essential for murine naïve pluripotency	32
Abscisic acid biosynthesis is necessary for full auxin effects on hypocotyl elongation	32
Cadherin adhesion complexes direct cell aggregation in the epithelial transition of Wnt-induced nephron progenitor cells	32
The functional specificity of ERECTA-family receptors in Arabidopsis stomatal development is ensured by molecular chaperones in the endoplasmic reticulum	32
Zasp52 strengthens whole embryo tissue integrity through supracellular actomyosin networks	32
FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton	32
Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans	31
Testosterone acts through the membrane protein GPRC6A to cause cardiac edema in zebrafish embryos	31
The impact of cell size on morphogen gradient precision	31
SOX2 transcription factor binding and function	31
PBAF chromatin remodeler complexes that mediate meiotic transitions in mouse	31
HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples	31
In preprints: shaping the developing human brain	30
The extra-embryonic area opaca plays a role in positioning the primitive streak of the early chick embryo	30
Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects	30
Modeling mammalian spermatogonial differentiation and meiotic initiationin vitro	30
A lissencephaly-associated BAIAP2 variant causes defects in neuronal migration during brain development	30
Wnt7b expressed by hypertrophic chondrocytes is a stimulatory factor for endochondral ossification that is regulated by Smad4 activity	30
Insights into the role of immune cells in development and regeneration	30
The insulator BEAF32 controls the spatial-temporal expression profile of the telomeric retrotransposon TART in the Drosophila germline	30
Ribosome biogenesis and function in development and disease	30
Transitions in development – an interview with Peng Du	29
TIE1-dependent lymphatic vascular remodeling is mediated by its second tyrosine kinase domain	29
The people behind the papers – Yongjun Yin and David Ornitz	29
Microgel culture and spatial identity mapping elucidate the signalling requirements for primate epiblast and amnion formation	29
Transitions in development – an interview with Thibaut Brunet	29
In preprints: new insights into root stem cells and their diversity	29
In preprints: shrinking boundary cells reveal fluid flux in organogenesis	28
Multi-view confocal microscopy enables multiple organ and whole organism live-imaging	28
Intrinsic positional memory guides target-specific axon regeneration in the zebrafish vagus nerve	28
An interview with Scott Fraser	28

The people behind the papers – Julia Grzymkowski and Nanette Nascone-Yoder	28
Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure	27
Sequential and additive expression of miR-9 precursors control timing of neurogenesis	27
Destabilization of mRNAs enhances competence to initiate meiosis in mouse spermatogenic cells	27
PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes	27
Transitions in development – an interview with Antonio Scialdone	27
The H2Bub1-deposition complex is required for human and mouse cardiogenesis	27
Single-cell reconstruction with spatial context of migrating neural crest cells and their microenvironments during vertebrate head and neck formation	27
Krüppel-like factor gene function in the ctenophore Mnemiopsis leidyi assessed by CRISPR/Cas9-mediated genome editing	27
PFN4 is required for manchette development and acrosome biogenesis during mouse spermiogenesis	27
Supracellular actomyosin assemblies: master coordinators of development	26
rasa1-related arteriovenous malformation is driven by aberrant venous signalling	26
mBeRFP: a versatile fluorescent tool to enhance multichannel live imaging and its applications	26
Real-time monitoring of an endogenous Fgf8a gradient attests to its role as a morphogen during zebrafish gastrulation	26
Prostate organogenesis	26
Parallels between oncogene-driven cardiac hyperplasia and heart regeneration in zebrafish	26
Maf family transcription factors are required for nutrient uptake in the mouse neonatal gut	25
Single-cell genomics revolutionizes plant development studies across scales	25
The ERM-1 membrane-binding domain directs erm-1 mRNA localization to the plasma membrane in the C. elegans embryo	25
New wave theory	24
The chromatin source-sink hypothesis: a shared mode of chromatin-mediated regulations	24
Signalling pathway crosstalk stimulated by L-proline drives mouse embryonic stem cells to primitive-ectoderm-like cells	24
Single-cell transcriptomics identifies new blood cell populations in Drosophila released at the onset of metamorphosis	24
The Blimp-1 transcription factor acts in non-neuronal cells to regulate terminal differentiation of the Drosophila eye	24
Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development	24
Anatomy and development of the pectoral fin vascular network in the zebrafish	23
Celsr1 suppresses Wnt5a-mediated chemoattraction to prevent incorrect rostral migration of facial branchiomotor neurons	23
VitelloTag: a tool for high-throughput cargo delivery into oocytes	23
The people behind the papers – Alfahdah Alsudayri and Lihua Ye	23
The Hox code responsible for the patterning of the anterior vertebrae in zebrafish	23
Cell-type-specific interacting proteins collaborate to regulate the timing of Cyclin B protein expression in male meiotic prophase	23
Keeping up with the Node	22
Oxygen-sensing mechanisms in development and tissue repair	22
The people behind the papers – Alyshia Scholl, Yihong Liu and Geraldine Seydoux	22
A transit-amplifying progenitor with biphasic behavior contributes to epidermal renewal	22
A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body	22
Advancing stem cell technologies for conservation of wildlife biodiversity	22
In preprints: an evo-devo approach integrates multicellular shape diversity and active surface mechanics	22
An in vivo CRISPR screen in chick embryos reveals a role for MLLT3 in specification of neural cells from the caudal epiblast	22
The people behind the papers – Vahid Zadmajid and Daniel Gorelick	22
Cell division angle predicts the level of tissue mechanics that tune the amount of cerebellar folding	22
Single-cell organogenesis captures complex breast tissue formation in 3D	21
Cell-cell communication through FGF4 generates and maintains robust proportions of differentiated cell types in embryonic stem cells	21
Traip controls mushroom body size by suppressing mitotic defects	21
The MEK-ERK signaling pathway promotes maintenance of cardiac chamber identity	21
TOR signalling mediates the collective movement of Border cells in Drosophila oogenesis	21
Pathway to Independence – an interview with Toshimichi Yamada	21
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology	21
Disruption of placental ACKR3 impairs growth and hematopoietic development of offspring	21
Microglia refine developing retinal astrocytic and vascular networks through the complement C3/C3aR axis	21
The people behind the papers – Emily Bulger and Benoit Bruneau	21
Caenorhabditis elegans LET-381 and DMD-4 control development of the mesodermal HMC endothelial cell	21
GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism	21
The people behind the papers – Keiji Itoh and Sergei Sokol	21
The people behind the papers – Bénédicte Marie Lefèvre and Michael Lang	21
Contribution of vasculature to stem integrity in Arabidopsis thaliana	21
Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle	21
Dynamic de novo adipose tissue development during metamorphosis in Drosophila melanogaster	21
Hemocytes are essential for Drosophila melanogaster post-embryonic development, independent of control of the microbiota	21
Hindbrain boundaries as niches of neural progenitor and stem cells regulated by the extracellular matrix proteoglycan chondroitin sulphate	21
Loss of perinuclear theca ACTRT1 causes acrosome detachment and severe male subfertility in mice	20
Pleiotropy of autism-associated chromatin regulators	20
Correction: Transcriptional dynamics during karyogamy in rice zygotes	20
Confinement promotes nematic alignment of spindle-shaped cells during Drosophila embryogenesis	20
In preprints: the extracellular matrix influences primordial germ cell behavior	20
The people behind the papers – Juan Yang and Xuanmao Chen	20
Tubb4b is required for multi-ciliogenesis in the mouse	20
A comparative analysis of TonEBP conditional knockout mouse models reveals inter-dependency between compartments of the intervertebral disc	20
Transitions in development – an interview with Daniel Ríos Barrera	20
Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways	20
E93 is indispensable for reproduction in ametabolous and hemimetabolous insects	20
Conserved roles of ETT and ARF4 in gynoecium development in Brassicaceae with distinct fruit shapes	20
Normal Table of Xenopus development: a new graphical resource	20
Development's 2023 Outstanding Paper Prize	20
Unlocking the potential of SY-stem cells	20
Interaction of Gαi2 with EB1 controls microtubule dynamics and Rac1 activity in Xenopus neural crest cell migration	20
FOXP4 differentially controls cold-induced beige adipocyte differentiation and thermogenesis	20
Elevated numbers of infiltrating eosinophils accelerate the progression of Duchenne muscular dystrophy pathology in mdx mice	20
Cranium growth, patterning and homeostasis	20
Tissue-specific RNA-seq defines genes governing male tail tip morphogenesis in C. elegans	20

In preprints: lifetime changes in leaf shape	20
Pathway to Independence – an interview with Clémentine Villeneuve	19
Multiple cis-regulatory elements control prox1a expression in distinct lymphatic vascular beds	19
Epha1 is a cell-surface marker for the neuromesodermal competent population	19
In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary	19
Correction: Zebrafish dazl regulates cystogenesis and germline stem cell specification during the primordial germ cell to germline stem cell transition	19
Lineage-based scaling of germline intercellular bridges during oogenesis	19
Wnt9 directs zebrafish heart tube assembly via a combination of canonical and non-canonical pathway signaling	19
The people behind the papers – Dennis de Bakker, Mara Bouwman and Jeroen Bakkers	19
Transitions in development – an interview with Kara McKinley	19
Transitions in development – an interview with Salah Elias	19
The dynamics of tubulogenesis in development and disease	18
Quantitative live imaging of floral organ initiation and floral meristem termination in Aquilegia	18
Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons	18
The people behind the papers – Danielle Spitzer and Iswar Hariharan	18
Transitions in development – an interview with Evgeny Kvon	18
BET activity plays an essential role in control of stem cell attributes in Xenopus	18
Single-minded 2 is required for left-right asymmetric stomach morphogenesis	18
Different temporal requirements for tartan and wingless in the formation of contractile interfaces at compartmental boundaries	18
Reduction of cortical parvalbumin-expressing GABAergic interneurons in a rodent hyperoxia model of preterm birth brain injury with deficits in social behavior and cognition	18
Excess dietary sugar impairs Drosophila adult stem cells via elevated reactive oxygen species-induced JNK signaling	18
Drosophila CTP synthase regulates collective cell migration by controlling the polarized endocytic cycle	18
Generative model for the first cell fate bifurcation in mammalian development	18
An inducible germ cell ablation chicken model for high-grade germline chimeras	18
Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion	18
An ancient testis-specific IQ motif-containing H gene regulates specific transcript isoform expression during spermatogenesis	17
FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice	17
Notch signaling in neurogenesis	17
Pathway to Independence – an interview with Marcella Birtele	17
A renaissance for developmental biology driven by new in vitro platforms	17
NHR-23 activity is necessary for C. elegans developmental progression and apical extracellular matrix structure and function	17
De novo PAM generation to reach initially inaccessible target sites for base editing	17
Compensation of gene dosage on the mammalian X	17
Mammalian DNA methylome dynamics: mechanisms, functions and new frontiers	17
Direct force measurement and loading on developing tissues in intact avian embryos	17
The brain on time: links between development and neurodegeneration	17
The miR156 juvenility factor and PLETHORA 2 form a regulatory network and influence timing of meristem growth and lateral root emergence	17
Orb-dependent polyadenylation contributes to PLP expression and centrosome scaffold assembly	17
The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance	17
Msl3 promotes germline stem cell differentiation in female Drosophila	17
LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation	17
Suppression of YAP safeguards human naïve pluripotency	17
The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis	17
PUF-8, a C. elegans ortholog of the RNA-binding proteins PUM1 and PUM2, is required for robustness of the cell death fate	17
regeneration factors expressed on myeloid expression in macrophage-like cells is required for tail regeneration in Xenopus laevis tadpoles	17
PLETHORA transcription factors promote early embryo development through induction of meristematic potential	16
Sculpting with stem cells: how models of embryo development take shape	16
Cyclical endometrial repair and regeneration	16
The cellular function of ROP GTPase prenylation is important for multicellularity in the moss Physcomitrium patens	16
A constitutively expressed fluorescent ubiquitination-based cell-cycle indicator (FUCCI) in axolotls for studying tissue regeneration	16
Control of fate specification within the dorsal head of Drosophila melanogaster	16
The cell-adhesion molecule Echinoid promotes tissue survival and separately restricts tissue overgrowth	16
The people behind the papers – Justina Stark, Ivo Sbalzarini and Michael Brand	16
Exploring the principles of embryonic mammary gland branching morphogenesis	16
Building and rebuilding complex tissues: strategic visions from a research-led workshop	16
Astrocyte-intrinsic and -extrinsic Fat1 activities regulate astrocyte development and angiogenesis in the retina	16
Enhancer RNAs step forward: new insights into enhancer function	16
An end-to-end pipeline based on open source deep learning tools for reliable analysis of complex 3D images of ovaries	16
Dissecting pleiotropic functions of the wheat Green Revolution gene Rht-B1b in plant morphogenesis and yield formation	16
IL7Rα, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells	16
Pivotal role of STIP in ovule pattern formation and female germline development in Arabidopsis thaliana	16
A high-sugar diet, but not obesity, reduces female fertility in Drosophila melanogaster	16
Evolution of the regulation of developmental gene expression in blind Mexican cavefish	16
A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals	16
Expanding the evo-devo toolkit: generation of 3D mammary tissue from diverse mammals	16
Adaxial-abaxial bipolar leaf genes encode a putative cytokinin receptor and HD-Zip III, and control the formation of ectopic shoot meristems in rice	16
Prrx1b restricts fibrosis and promotes Nrg1-dependent cardiomyocyte proliferation during zebrafish heart regeneration	16
Induced regeneration of articular cartilage – identification of a dormant regeneration program for a non-regenerative tissue	16
Transplanted human intestinal organoids: a resource for modeling human intestinal development	16
Gibberellin and miRNA156-targeted SlSBP genes synergistically regulate tomato floral meristem determinacy and ovary patterning	16
Environmental and molecular control of tissue-specific ionocyte differentiation in zebrafish	16
Motor neurons in the tunicate caudal central nervous system reveal homology to the vertebrate spinal cord	16
New year, new developments: a look back and a look ahead	16
Adipose triglyceride lipase promotes prostaglandin-dependent actin remodeling by regulating substrate release from lipid droplets	16
Cre recombinase microinjection for single-cell tracing and localised gene targeting	16
Development of the mammalian main olfactory bulb	16
Defining the Hoxb8 cell lineage during murine definitive hematopoiesis	16
The people behind the papers – Wendy Duan and Meghan Riddell	15
Constructive Critics: Development's approach to peer review	15
Intercellular contact and cargo transfer between Müller glia and to microglia precede apoptotic cell clearance in the developing retina	15
Female meiosis II and pronuclear fusion require the microtubule transport factor Bicaudal D	15
Human developmental biology – a global perspective	15
TAF4b transcription networks regulating early oocyte differentiation	15
Human stem cell models to study placode development, function and pathology	15
Retrovirus-derived RTL5 and RTL6 genes are novel constituents of the innate immune system in the eutherian brain	15
Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes	15
Rac1 and Nectin3 are essential for planar cell polarity-directed axon guidance in the peripheral auditory system	15
The people behind the papers – Jonas Malkmus, Rushikesh Sheth and Rolf Zeller	15
Live imaging of retinotectal mapping reveals topographic map dynamics and a previously undescribed role for Contactin 2 in map sharpening	15
Development's 2024 outstanding paper prize	15
Mechanical stress combines with planar polarised patterning during metaphase to orient embryonic epithelial cell divisions	15
Temporally and regionally distinct morphogenetic processes govern zebrafish caudal fin blood vessel network expansion	15
The matrix glycoprotein Papilin maintains the haematopoietic progenitor pool in Drosophila lymph glands	15
Heterologous expression of a lycophyte protein enhances angiosperm seedling vigor	15
The fetal lineage is susceptible to Zika virus infection within days of fertilization	15