Journal of Molecular Medicine-Jmm

Article	Citations
The PER3rs772027021 SNP induces pigmentation phenotypes of dyschromatosis universalis hereditaria	80
PCDH11X mutation as a potential biomarker for immune checkpoint therapies in lung adenocarcinoma	74
Silencing of Mcl-1 overcomes resistance of melanoma cells against TRAIL-armed oncolytic adenovirus by enhancement of apoptosis	72
Mitochondrial transplantation as a possible therapeutic option for sarcopenia	66
Neurovascular abnormalities in retinopathy of prematurity and emerging therapies	62
Flotillin- 1 ameliorates experimental diabetic retinopathy by inhibiting ferroptosis in blood-retinal barrier	60
Histone modification in podocyte injury of diabetic nephropathy	57
LMO3 reprograms visceral adipocyte metabolism during obesity	53
IGFBP2 function as a novel biomarker for active lupus nephritis	53
Metabolomics reveals that chronic restraint stress alleviates carbon tetrachloride-induced hepatic fibrosis through the INSR/PI3K/AKT/AMPK pathway	45
Pathogenic effects of Leu200Pro and Arg387His VRK1 protein variants on phosphorylation targets and H4K16 acetylation in distal hereditary motor neuropathy	38
Nets, pulmonary arterial hypertension, and thrombo-inflammation	38
CircRNA CDR1AS promotes cardiac ischemia–reperfusion injury in mice by triggering cardiomyocyte autosis	35
Valproic acid modulates collagen architecture in the postoperative conjunctival scar	35
Mesenchymal stem cell–derived extracellular vesicles in periodontal bone repair	35
Genotypic analysis of a large cohort of patients with suspected atypical hemolytic uremic syndrome	34
A comprehensive review of m6 A methylation in coronary heart disease	33
Correction to: Local Wnt3a treatment restores bone regeneration in large osseous defects after surgical debridement of osteomyelitis	33
Circular RNAs: regulators of vascular smooth muscle cells in cardiovascular diseases	31
Acid-sensing ion channel 1a exacerbates renal ischemia–reperfusion injury through the NF-κB/NLRP3 inflammasome pathway	31
Sphingosine kills Mycobacteria and suppresses mycobacterial lung infections	31
CREB-H is a stress-regulator of hepcidin gene expression during early postnatal development	29
Microdevices for cancer stem cell culture as a predictive chemotherapeutic response platform	29
PAX5 aberrant expression incorporated in MIPI-SP risk scoring system exhibits additive value in mantle cell lymphoma	28
Expression of PKM2 in wound keratinocytes is coupled to angiogenesis during skin repair in vivo and in HaCaT keratinocytes in vitro	28

Synergistic effect of the sphingosine kinase inhibitor safingol in combination with 2'-nitroflavone in breast cancer	27
Leukocyte cytokine responses in adult patients with mitochondrial DNA defects	26
Inhibition of p38 MAPK decreases hyperglycemia-induced nephrin endocytosis and attenuates albuminuria	26
Possible implication of miR-142-3p in coronary microembolization induced myocardial injury via ATXN1L/HDAC3/NOL3 axis	26
Correction to: Liquid biopsies for multiple myeloma in a time of precision medicine	26
Research progress and application of liver organoids for disease modeling and regenerative therapy	25
Rare and low-frequency variants in families with otitis media	25
Retraction Note: Radiation-induced glucocorticoid receptor promotes CD44 + prostate cancer stem cell growth through activation of SGK1-Wnt/β-catenin signaling	24
Bicuspid aortic valve aortopathy is characterized by embryonic epithelial to mesenchymal transition and endothelial instability	24
Progress in diagnosis and treatment of Leber’s hereditary optic neuropathy	23
Macrophage co-culture promotes cell reprogramming and prevents ferroptosis in aging fibroblasts for neurodegeneration therapy	23
DNA origami: a tool to evaluate and harness transcription factors	22
RNA-Seq for the detection of gene fusions in solid tumors: development and validation of the JAX FusionSeq™ 2.0 assay	22
Vav2 promotes ductus arteriosus anatomic closure via the remodeling of smooth muscle cells by Rac1 activation	22
Identification of mutational signature for lung adenocarcinoma prognosis and immunotherapy prediction	21
Integration of clinical characteristics and molecular signatures of the tumor microenvironment to predict the prognosis of neuroblastoma	21
Correction to: Cross‑reactive, natural IgG recognizing L. major promote parasite internalization by dendritic cells and promote protective immunity	21
The plasma exosomes from patients with primary Sjögren’s syndrome contain epithelial cell–derived proteins involved in ferroptosis	21
Targeting ferroptosis for the treatment of female reproductive system disorders	21
The role of ceRNAs in breast cancer microenvironmental regulation and therapeutic implications	21
Transcriptional changes in multiple endocrine organs from lethal cases of COVID-19	20
Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels	20
Systemic and local effect of oxidative stress on recurrent aphthous stomatitis: systematic review	20
Kielin/chordin-like protein deficiency causes cardiac aging in male mice	20
Circulating extracellular vesicles are associated with pathophysiological condition including metabolic syndrome-related dysmetabolism in children and adolescents with obesity	20
Correction to: PRMT4 drives post-ischemic angiogenesis via YB1/VEGF signaling	20
Central dopamine receptors: Radiotracers unveiling the Role of dopaminergic tone in obesity	19
Recessive ciliopathy mutations in primary endocardial fibroelastosis: a rare neonatal cardiomyopathy in a case of Alstrom syndrome	19
Predisposition to Graves’ disease and Graves’ ophthalmopathy by genetic variants of IL2RA	18
RNA sequencing reveals induction of specific renal inflammatory pathways in a rat model of malignant hypertension	18
Retraction Note: Stabilization of the histone acetyltransferase Tip60 by deubiquitinating enzyme USP7 stimulates the release of pro-inflammatory mediators in acute lung injury	18
Zinc finger and BTB domain-containing protein 20 aggravates angiotensin II-induced cardiac remodeling via the EGFR-AKT pathway	18
Therapeutic modulation of JAK-STAT, mTOR, and PPAR-γ signaling in neurological dysfunctions	17
Histone deacetylase 3 (HDAC3) as an important epigenetic regulator of kidney diseases	17
Statin therapy protects against abdominal aortic aneurysms by inducing the accumulation of regulatory T cells in ApoE−/− mice	17
Elucidation of endothelial progenitor cell dysfunction in diabetes by RNA sequencing and constructing lncRNA–miRNA–mRNA competing endogenous RNA network	17
Syncytin-1, syncytin-2 and suppressyn in human health and disease	17
Soluble angiotensin-converting enzyme levels in heart failure or acute coronary syndrome: revisiting its modulation and prognosis value	17
FoxO3 and oxidative stress: a multifaceted role in cellular adaptation	17
Exploring endothelial dysfunction in major rheumatic diseases: current trends and future directions	17
Dispensable role of Rac1 and Rac3 after cochlear hair cell specification	16
Extragustatory bitter taste receptors in head and neck health and disease	16
Genetic abnormalities in biopsy-proven, adult-onset hemolytic uremic syndrome and C3 glomerulopathy	16
Nischarin expression may have differing roles in male and female melanoma patients	16
Copper chaperone antioxidant 1: multiple roles and a potential therapeutic target	15
EVs vs. EVs: MSCs and Tregs as a source of invisible possibilities	15
Rare variants in cardiomyopathy genes predispose to cardiac injury in severe COVID-19 patients of African or Hispanic ancestry	15
Simultaneous targeting of mitochondrial Kv1.3 and lysosomal acid sphingomyelinase amplifies killing of pancreatic ductal adenocarcinoma cells in vitro and in vivo	15
Large extracellular vesicles derived from human regulatory macrophages (L-EVMreg) attenuate CD3/CD28-induced T-cell activation in vitro	15
The regulatory role of LncRNA HCG18 in various cancers	14

EV-T synergizes with AZD5582 to overcome TRAIL resistance through concomitant suppression of cFLIP, MCL-1, and IAPs in hepatocarcinoma	14
Are there foetal extracellular vesicles in maternal blood? Prospects for diagnostic biomarker discovery	14
Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells	14
Correction to: Matrix metalloproteinase‑7 induces E‑cadherin cleavage in acid‑exposed primary human pharyngeal epithelial cells via the ROS/ERK/c‑Jun pathway	14
Exosomal miR-21-5p derived from endometrial stromal cells promotes angiogenesis by targeting TIMP3 in ovarian endometrial cysts	13
Abnormal protein SUMOylation in liver disease: novel target for therapy	13
Recent advances in the molecular mechanisms of low-intensity pulsed ultrasound against inflammation	13
The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration	13
Targeting EphA2: a promising strategy to overcome chemoresistance and drug resistance in cancer	13
Retinal tissue develops an inflammatory reaction to tobacco smoke and electronic cigarette vapor in mice	13
DSPE-PEG2000-methotrexate nanoparticles encapsulating phenobarbital sodium kill cancer cells by inducing pyroptosis	13
Acid sphingomyelinase expression is associated with survival in resectable pancreatic ductal adenocarcinoma	13
VSMC-specific TRPC1 deletion attenuates angiotensin II-induced hypertension and cardiovascular remodeling	13
Lipidomic insights on abdominal aortic aneurysm and peripheral arterial disease	13
The vasculature niches required for hematopoiesis	13
Two-trace two-dimensional correlation spectra (2T2D-COS) analysis using FTIR spectra to monitor the immune response by COVID-19	13
Loss-of-function mutation in DDX53 associated with hereditary spastic paraplegia-like disorder	12
Correction to: The recurrent missense mutation p.(Arg367Trp) in YARS1 causes a distinct neurodevelopmental phenotype	12
JAK2 regulates paclitaxel resistance in triple negative breast cancers	12
Protective role of M3 muscarinic acetylcholine receptor in indomethacin-induced small intestinal injury	12
Suppression of PGE2/EP2 signaling alleviates Hirschsprung disease by upregulating p38 mitogen-activated protein kinase activity	12
Loss of CAA interruption and intergenerational CAG instability in Chinese patients with Huntington’s disease	12
Identification of STAT3 and MYC as critical ferroptosis-related biomarkers in septic cardiomyopathy: a bioinformatics and experimental study	12
Protective mechanisms of loquat leaf extract and ursolic acid against diabetic pro-inflammation	12
The oncogenic role of EIF4A3/CDC20 axis in the endometrial cancer	11
Acyloxyacyl hydrolase deficiency induces chronic inflammation and bone loss in male mice	11
Exploring the role of tRNA-derived small RNAs (tsRNAs) in disease: implications for HIF-1 pathway modulation	11
Long noncoding RNA HAR1A regulates oral cancer progression through the alpha-kinase 1, bromodomain 7, and myosin IIA axis	10
Altered expression of Sialyl Lewis X in experimental models of Parkinson’s disease	10
Correction to: Downregulation of microRNA-193a-3p is involved in invertebral disc degeneration by targeting MMP14	10
The role of the immunosuppressive PD-1/PD-L1 checkpoint pathway in the aging process and age-related diseases	10
Regulation of innate lymphoid cell by microbial metabolites	10
Metformin improves cognitive dysfunction through SIRT1/NLRP3 pathway–mediated neuroinflammation in db/db mice	10
ASK1 is a novel molecular target for preventing aminoglycoside-induced hair cell death	10
Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations	10
Regulation of wound healing and fibrosis by galectins	10
Etiopathogenesis of medication-related osteonecrosis of the jaws: a review	10
Endocrine resistance in breast cancer: from molecular mechanisms to therapeutic strategies	10
SMARCC1 promotes M2 macrophage polarization and reduces ferroptosis in lung cancer by activating FLOT1 transcription	10
Dual roles of UPRer and UPRmt in neurodegenerative diseases	9
Pkhd1cyli/cyli mice have altered renal Pkhd1 mRNA processing and hormonally sensitive liver disease	9
The FOXO family of transcription factors: key molecular players in gastric cancer	9
Peroxiredoxins in erythrocytes: far beyond the antioxidant role	9
New CRISPR/Cas9-based Fgfr2C361Y/+ mouse model of Crouzon syndrome exhibits skull and behavioral abnormalities	9
Correction to: Antioxidative effects of polypyrimidine tract-binding protein-associated splicing factor against pathological retinal angiogenesis through promotion of mitochondrial function	9
Evaluation of EpCAM-specific exosomal lncRNAs as potential diagnostic biomarkers for lung cancer using droplet digital PCR	9
Umbelliferone alleviates impaired wound healing and skin barrier dysfunction in high glucose-exposed dermal fibroblasts and diabetic skins	9
SOST gene suppression stimulates osteocyte Wnt/β-catenin signaling to prevent bone resorption and attenuates particle-induced osteolysis	9
Mitochondria targeted esculetin administration improves insulin resistance and hyperglycemia-induced atherosclerosis in db/db mice	9
Hypoxia drives estrogen receptor β-mediated cell growth via transcription activation in non-small cell lung cancer	9
Correction to: Traumatic brain injury-induced downregulation of Nrf2 activates inflammatory response and apoptotic cell death	9
Insufficient SIRT1 in macrophages promotes oxidative stress and inflammation during scarring	9
ATF3 in atherosclerosis: a controversial transcription factor	9
Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers	9
NLRC3 attenuates osteoclastogenesis by limiting TNFα+ Th17 cell response in osteoporosis	9
Periostin secreted by cancer-associated fibroblasts promotes cancer progression and drug resistance in non-small cell lung cancer	9
Selective blood-nerve barrier leakiness with claudin-1 and vessel-associated macrophage loss in diabetic polyneuropathy	8
A novel RBBP8(p.E281*) germline mutation is a predisposing mutation in familial hereditary cancer syndrome	8
Epigenetic mechanisms regulate sex-specific bias in disease manifestations	8
Role of endosomal RANKL–LGR4 signaling during osteoclast differentiation	8
Identifying survival of pan-cancer patients under immunotherapy using genomic mutation signature with large sample cohorts	8
Expression and function of Smad7 in autoimmune and inflammatory diseases	8
LKB1-PTEN axis controls Th1 and Th17 cell differentiation via regulating mTORC1	8
New insights into macrophage subsets in atherosclerosis	8
Traumatic brain injury-induced disruption of the circadian clock	8
Emerging therapeutic targets in systemic sclerosis	8
PTEN-induced kinase 1 deficiency alters albumin permeability and insulin signaling in podocytes	8
Non-coding RNAs regulating mitochondrial function in cardiovascular diseases	8
New insights into the mechanisms and therapeutic strategies of chondrocyte autophagy in osteoarthritis	8
Ataluren suppresses a premature termination codon in an MPS I-H mouse	8
Physiological and pathological effects of phase separation in the central nervous system	8
Lipid accumulation and novel insight into vascular smooth muscle cells in atherosclerosis	8
High glucose: an emerging association between diabetes mellitus and cancer progression	7
WNT2B high‑expressed fibroblasts induce the fibrosis of IBD by promoting NK cells secreting IL-33	7
Genetically determined blood lead is associated with reduced renal function amongst individuals with type 2 diabetes mellitus: insight from Mendelian Randomisation	7
Sphingolipids: drivers of cardiac fibrosis and atrial fibrillation	7
Histone H3K9 methyltransferase SETDB1 overexpression correlates with pediatric high-grade gliomas progression and prognosis	7
Regulation of endothelial progenitor cell functions during hyperglycemia: new therapeutic targets in diabetic wound healing	7
Mediator kinase inhibition drives myometrial stem cell differentiation and the uterine fibroid phenotype through super-enhancer reprogramming	7
Lipid metabolism, inflammation, and foam cell formation in health and metabolic disorders: targeting mTORC1	7

Underlying mechanisms of epithelial splicing regulatory proteins in cancer progression	7
The scaffold-dependent function of RIPK1 in experimental non-alcoholic steatohepatitis	7
Hereditary non-spherocytic hemolytic anemia with GPI mutations successfully treated with allogeneic hematopoietic stem cell transplantation: a first report of two cases	7
Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective	7
Identification of a novel eighteen-gene signature of recurrent metastasis neuroblastoma	7
Constitutive expression of the deubiquitinating enzyme CYLD does not affect microglia phenotype or function in homeostasis and neuroinflammation	7
Retraction Note: Antioxidative effects of polypyrimidine tract-binding protein-associated splicing factor against pathological retinal angiogenesis through promotion of mitochondrial function	7
Upregulation of glycolytic enzyme PFKFB3 by deubiquitinase OTUD4 promotes cardiac fibrosis post myocardial infarction	6
The role of immunosuppressive myofibroblasts in the aging process and age-related diseases	6
The role of the individual TOM subunits in the association of PINK1 with depolarized mitochondria	6
MiR-30c-1-3p targets matrix metalloproteinase 9 involved in the rupture of abdominal aortic aneurysms	6
TFEB: a double-edged sword for tumor metastasis	6
Purinergic signaling elements are correlated with coagulation players in peripheral blood and leukocyte samples from COVID-19 patients	6
Soluble LDL-receptor is induced by TNF-α and inhibits hepatocytic clearance of LDL-cholesterol	6
Hepatic microtubule destabilization facilitates liver fibrosis in the mouse model of Wilson disease	6
Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome	6
Eucalyptol induces osteoblast differentiation through ERK phosphorylation in vitro and in vivo	6
Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight	6
Current knowledge of bone-derived factor osteocalcin: its role in the management and treatment of diabetes mellitus, osteoporosis, osteopetrosis and inflammatory joint diseases	6
Mechanistic complement of autosomal dominant polycystic kidney disease: the role of aquaporins	6
MicroRNAs role in telomere length maintenance and telomerase activity in tumor cells	6
β-Adrenergic blockade attenuates adverse adipose tissue responses after burn	6
ABCB1 in dermatology: roles in skin diseases and their treatment	6
Kat7 accelerates osteoarthritis disease progression through the TLR4/NF-κB signaling pathway	6
Mechanism of efferocytosis in atherosclerosis	6
Non-invasive biomarkers prognostic of decompensation events in NASH cirrhosis: a systematic literature review	6
Molecular mechanisms of thalidomide effectiveness on COVID-19 patients explained: ACE2 is a new ΔNp63α target gene	6
Synthetic polypeptide crotamine: characterization as a myotoxin and as a target of combinatorial peptides	6
The multiple functions of PrPC in physiological, cancer, and neurodegenerative contexts	6
Longitudinal study on immunologic, lipoproteomic, and inflammatory responses indicates the safety of sequential COVID-19 vaccination	6
Systematic and quantitative analysis of stop codon readthrough in Rett syndrome nonsense mutations	6
GSK-3α aggravates inflammation, metabolic derangement, and cardiac injury post-ischemia/reperfusion	6
Evaluation of circulating glypican 4 as a novel biomarker in disease – A comprehensive review	6
Multiple sclerosis is linked to MAPKERK overactivity in microglia	6
Recent updates on targeting the molecular mediators of NAFLD	6
Nicotinamide riboside kinase-2 regulates metabolic adaptation in the ischemic heart	6
Extracellular matrix remodeling in animal models of anthracycline-induced cardiomyopathy: a meta-analysis	5
The interplay of DAMPs, TLR4, and proinflammatory cytokines in pulmonary fibrosis	5
Correction to: Arginine derivatives in atrial fibrillation progression phenotypes	5
Correction to: ASK1 is a novel molecular target for preventing aminoglycoside‑induced hair cell death	5
Correction to: White and brown adipose tissue functionality is impaired by fine particulate matter (PM2.5) exposure	5
Predictive value of common genetic variants in idiopathic pulmonary fibrosis survival	5
Correction to: LncRNA GATA3‑AS1 promoted invasion and migration in human endometrial carcinoma by regulating the miR‑361/ARRB2 axis	5
Progranulin, a moderator of estrogen/estrogen receptor α binding, regulates bone homeostasis through PERK/p-eIF2 signaling pathway	5
SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?	5
How calorie restriction slows aging: an epigenetic perspective	5
The TLR/MyD88 signalling cascade in inflammation and gastric cancer: the immune regulatory network of Helicobacter pylori	5
Endothelial glycocalyx degradation in multisystem inflammatory syndrome in children related to COVID-19	5
Aging- and alcohol-associated spatial transcriptomic signature in mouse acute pancreatitis reveals heterogeneity of inflammation and potential pathogenic factors	5
Correction to: Translation of curative therapy concepts with T cell and cytokine antibody combinations for type 1 diabetes reversal in the IDDM rat	5
The crosstalk between ubiquitination and endocrine therapy	5
Correction to: MiR‑30c‑1‑3p targets matrix metalloproteinase 9 involved in the rupture of abdominal aortic aneurysms	5
Role of the pioneer transcription factor GATA2 in health and disease	5
Functional roles of E3 ubiquitin ligases in prostate cancer	5
Ziprasidone suppresses pancreatic adenocarcinoma cell proliferation by targeting GOT1 to trigger glutamine metabolism reprogramming	5
FATP1-mediated fatty acid uptake in renal tubular cells as a countermeasure for hypothermia	5
Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation	5
Anti-fibrotic effects of pharmacologic FGF-2: a review of recent literature	5
Cardiovascular dysfunction and altered lysosomal signaling in a murine model of acid sphingomyelinase deficiency	5
The role of lncRNA in the differentiation of adipose-derived stem cells: from functions to mechanism	5
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology	5
Clinical significance of mutational variants in beta and alpha genes in patients with hemoglobinopathies from two large Greek centers: a complex interplay between genotype and phenotype	5
CD155 promotes the advancement of hepatocellular carcinoma by suppressing the p53-mediated ferroptosis via interacting with CD96	4
Emerging technologies in regenerative medicine: The future of wound care and therapy	4
CARMA1 is required for Notch1-induced NF-κB activation in SIL-TAL1-negative T cell acute lymphoblastic leukemia	4
Matrix metalloproteinase-7 induces E-cadherin cleavage in acid-exposed primary human pharyngeal epithelial cells via the ROS/ERK/c-Jun pathway	4
Blockade of aryl hydrocarbon receptor restricts omeprazole-induced chronic kidney disease	4
Early reduction of SARS-CoV-2-replication in bronchial epithelium by kinin B2 receptor antagonism	4
Celastrol-loaded biomimetic nanodrug ameliorates APAP-induced liver injury through modulating macrophage polarization	4
Correction to: Myeloid‑specific deletion of chitinase‑3‑like 1 protein ameliorates murine diet‑induced steatohepatitis progression	4
Abnormally accumulated GM2 ganglioside contributes to skeletal deformity in Tay-Sachs mice	4
Correction to: Evaluation of EpCAM-specific exosomal lncRNAs as potential diagnostic biomarkers for lung cancer using droplet digital PCR	4
Blocking prokineticin receptors attenuates synovitis and joint destruction in collagen-induced arthritis	4
Elevation of hsa-miR-7-5p level mediated by CtBP1-p300-AP1 complex targets ATXN1 to trigger NF-κB-dependent inflammation response	4
NLRP7 participates in the human subcortical maternal complex and its variants cause female infertility characterized by early embryo arrest	4
Role of non-coding RNA in immune microenvironment and anticancer therapy of gastric cancer	4
Mechanistic study of optic atrophy 1 in ischemia-reperfusion disease	4
Effects of different amosite preparations on macrophages, lung damages, and autoimmunity	4
Macrophage activation contributes to diabetic retinopathy	4
TRAP1 modulates mitochondrial biogenesis via PGC-1α/TFAM signalling pathway in colorectal cancer cells	4
Exploiting the therapeutic potential of contracting skeletal muscle-released extracellular vesicles in cancer: Current insights and future directions	4
Transcriptional repression of lncRNA and miRNA subsets mediated by LRF during erythropoiesis	4
Oral pyrophosphate protects Abcc6-/- mice against vascular calcification induced by chronic kidney disease	4
A comprehensive review on phytochemicals for fatty liver: are they potential adjuvants?	4