Journal of Molecular Medicine-Jmm

Article	Citations
Pathogenic effects of Leu200Pro and Arg387His VRK1 protein variants on phosphorylation targets and H4K16 acetylation in distal hereditary motor neuropathy	133
Flotillin- 1 ameliorates experimental diabetic retinopathy by inhibiting ferroptosis in blood-retinal barrier	72
The PER3rs772027021 SNP induces pigmentation phenotypes of dyschromatosis universalis hereditaria	66
Anti-myeloma activity of the CXCR4 antagonist WZ811	65
IGFBP2 function as a novel biomarker for active lupus nephritis	61
PCDH11X mutation as a potential biomarker for immune checkpoint therapies in lung adenocarcinoma	54
Clinical utility of cerebrospinal fluid interleukin-10 in central nervous system lymphoma: a molecular neuropathology-informed diagnostic meta-analysis	52
Mitochondrial transplantation as a possible therapeutic option for sarcopenia	50
Histone modification in podocyte injury of diabetic nephropathy	44
Metabolomics reveals that chronic restraint stress alleviates carbon tetrachloride-induced hepatic fibrosis through the INSR/PI3K/AKT/AMPK pathway	40
Relationship between CXCR4 and GNG4 in the Brain and Chronic Stress-Induced Atherosclerosis	38
Synergistic effect of the sphingosine kinase inhibitor safingol in combination with 2'-nitroflavone in breast cancer	36
Microdevices for cancer stem cell culture as a predictive chemotherapeutic response platform	35
PAX5 aberrant expression incorporated in MIPI-SP risk scoring system exhibits additive value in mantle cell lymphoma	33
Rewriting the vascular script: epigenetic modifiers as scribes of metabolic reprogramming in pulmonary hypertension	33
CREB-H is a stress-regulator of hepcidin gene expression during early postnatal development	32
Sphingosine kills Mycobacteria and suppresses mycobacterial lung infections	30
CircRNA CDR1AS promotes cardiac ischemia–reperfusion injury in mice by triggering cardiomyocyte autosis	30
A comprehensive review of m6 A methylation in coronary heart disease	29
Mesenchymal stem cell–derived extracellular vesicles in periodontal bone repair	28
Genotypic analysis of a large cohort of patients with suspected atypical hemolytic uremic syndrome	28
Alcohol induces sorafenib resistance in hepatocellular carcinoma: A translational study	28
Acid-sensing ion channel 1a exacerbates renal ischemia–reperfusion injury through the NF-κB/NLRP3 inflammasome pathway	26
Fibrin as the mediator of tumor cell interaction with platelets	26
Macrophage co-culture promotes cell reprogramming and prevents ferroptosis in aging fibroblasts for neurodegeneration therapy	25

Expression of PKM2 in wound keratinocytes is coupled to angiogenesis during skin repair in vivo and in HaCaT keratinocytes in vitro	25
KAT2A affects the inflammatory progression of lupus nephritis through multilevel regulation of cGAS	25
Research progress and application of liver organoids for disease modeling and regenerative therapy	25
Vav2 promotes ductus arteriosus anatomic closure via the remodeling of smooth muscle cells by Rac1 activation	24
Progress in diagnosis and treatment of Leber’s hereditary optic neuropathy	24
SUV39H1 regulates progression of pediatric diffuse high-grade gliomas through modulation of β-catenin/TCF4 levels	24
The plasma exosomes from patients with primary Sjögren’s syndrome contain epithelial cell–derived proteins involved in ferroptosis	24
Correction to: Liquid biopsies for multiple myeloma in a time of precision medicine	24
Rare and low-frequency variants in families with otitis media	23
The role of ceRNAs in breast cancer microenvironmental regulation and therapeutic implications	23
Targeting ferroptosis for the treatment of female reproductive system disorders	23
Bicuspid aortic valve aortopathy is characterized by embryonic epithelial to mesenchymal transition and endothelial instability	23
The critical role of LRG1 in pathological fibrosis	23
Tyrosine hydroxylase as a therapeutic target: insights from adrenergic nerve and TNBC cell interactions	23
Identification of mutational signature for lung adenocarcinoma prognosis and immunotherapy prediction	22
DNA origami: a tool to evaluate and harness transcription factors	22
Nicotinamide riboside alleviates sepsis-induced acute kidney injury by suppressing ferroptosis	21
Correction to: PRMT4 drives post-ischemic angiogenesis via YB1/VEGF signaling	21
Integration of clinical characteristics and molecular signatures of the tumor microenvironment to predict the prognosis of neuroblastoma	20
Whole genome DNA methylation profiles define Meniere’s disease subclusters	20
Kielin/chordin-like protein deficiency causes cardiac aging in male mice	20
Transcriptional changes in multiple endocrine organs from lethal cases of COVID-19	19
Elucidation of endothelial progenitor cell dysfunction in diabetes by RNA sequencing and constructing lncRNA–miRNA–mRNA competing endogenous RNA network	19
A bioactive soluble recombinant mouse LIGHT promotes effective tumor immune cell infiltration delaying tumor growth	19
Central dopamine receptors: Radiotracers unveiling the Role of dopaminergic tone in obesity	19
Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels	19
FoxO3 and oxidative stress: a multifaceted role in cellular adaptation	18
Therapeutic modulation of JAK-STAT, mTOR, and PPAR-γ signaling in neurological dysfunctions	18
Systemic and local effect of oxidative stress on recurrent aphthous stomatitis: systematic review	18
4-Hydroxychalcone alleviated Angiotensin II-induced atrial fibrillation via immunoproteasome-IKK-NF-κB signaling pathway modulation	18
Exploring endothelial dysfunction in major rheumatic diseases: current trends and future directions	17
DAPL1 is activated by Np63 and GRα and regulates lipid metabolism	17
Rare variants in cardiomyopathy genes predispose to cardiac injury in severe COVID-19 patients of African or Hispanic ancestry	17
Dispensable role of Rac1 and Rac3 after cochlear hair cell specification	17
Circulating extracellular vesicles are associated with pathophysiological condition including metabolic syndrome-related dysmetabolism in children and adolescents with obesity	17
Large extracellular vesicles derived from human regulatory macrophages (L-EVMreg) attenuate CD3/CD28-induced T-cell activation in vitro	17
cGAS-STING signaling pathway in MASLD and liver fibrosis	17
Syncytin-1, syncytin-2 and suppressyn in human health and disease	17
POFUT1 as a cancer biomarker: insights into its oncogenic mechanisms and clinical relevance	17
Unproductive alternative splicing of ATM exon 7: mapping of critical regulatory elements and identification of 34 spliceogenic variants	17
Copper chaperone antioxidant 1: multiple roles and a potential therapeutic target	16
Extragustatory bitter taste receptors in head and neck health and disease	16
Nischarin expression may have differing roles in male and female melanoma patients	16
ApoA5-CIDEC axis regulates hepatic lipid metabolism, inflammation, and fibrosis in MASLD	16
Simultaneous targeting of mitochondrial Kv1.3 and lysosomal acid sphingomyelinase amplifies killing of pancreatic ductal adenocarcinoma cells in vitro and in vivo	16
Targeted metabolomics reveals tricarboxylic acid cycle-related metabolites serve as predictive biomarkers for trastuzumab resistance in human epidermal growth factor receptor 2-positive breast cancer	16
EVs vs. EVs: MSCs and Tregs as a source of invisible possibilities	16
DSPE-PEG2000-methotrexate nanoparticles encapsulating phenobarbital sodium kill cancer cells by inducing pyroptosis	15
Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells	15
Are there foetal extracellular vesicles in maternal blood? Prospects for diagnostic biomarker discovery	15

Live-cell imaging reveals decreased cAMP in a PFE-associated c.1050-3C>G PTH1R cell model	15
Lipidomic insights on abdominal aortic aneurysm and peripheral arterial disease	15
Longitudinal analysis in Mecp2-het female mice reveals atypical nociceptive behaviours	15
Oleanolic acid modulates neuronal regeneration through KLF5-mediated FGF13 mRNA degradation to alleviate Alzheimer’s disease-like cognitive dysfunction	14
Abnormal protein SUMOylation in liver disease: novel target for therapy	14
Exosomal miR-21-5p derived from endometrial stromal cells promotes angiogenesis by targeting TIMP3 in ovarian endometrial cysts	14
Nuclear factor IX promotes endometriosis progression through transcriptional activation of tetraspanin-2	14
The regulatory role of LncRNA HCG18 in various cancers	14
Targeting EphA2: a promising strategy to overcome chemoresistance and drug resistance in cancer	14
Recent advances in the molecular mechanisms of low-intensity pulsed ultrasound against inflammation	14
Metformin sensitizes endometriosis to medroxyprogesterone acetate treatment through MIG-6 mediated signaling	14
Two-trace two-dimensional correlation spectra (2T2D-COS) analysis using FTIR spectra to monitor the immune response by COVID-19	14
VSMC-specific TRPC1 deletion attenuates angiotensin II-induced hypertension and cardiovascular remodeling	14
Loss-of-function mutation in DDX53 associated with hereditary spastic paraplegia-like disorder	13
Vasoactive intestinal peptide advances chondrogenesis and modulates pathogenic mediators in human osteoarthritis	13
Role of PANoptosis in intestinal diseases and its therapeutic implications	13
Exploring the role of tRNA-derived small RNAs (tsRNAs) in disease: implications for HIF-1 pathway modulation	13
Protective role of M3 muscarinic acetylcholine receptor in indomethacin-induced small intestinal injury	13
Identification of STAT3 and MYC as critical ferroptosis-related biomarkers in septic cardiomyopathy: a bioinformatics and experimental study	13
Nintedanib reduces severity of post-traumatic joint contracture by modulating fibrosis and inflammation	13
Suppression of PGE2/EP2 signaling alleviates Hirschsprung disease by upregulating p38 mitogen-activated protein kinase activity	13
SIRT1 regulates CaOx crystal-induced exacerbation of renal mitochondrial dysfunction and fibrosis through PPAR-α in aged mice	13
Melatonin protects liver and periodontal tissues from inflammation exacerbated by metabolic syndrome–periodontitis association	13
Altered expression of Sialyl Lewis X in experimental models of Parkinson’s disease	12
Correction to: Diacerein improves liver fibrosis, steatosis, and atherosclerosis in ApoE knockout mice	12
Dilated cardiomyopathy in patients with PRDM16 haploinsufficiency	12
Acyloxyacyl hydrolase deficiency induces chronic inflammation and bone loss in male mice	12
Loss of CAA interruption and intergenerational CAG instability in Chinese patients with Huntington’s disease	12
Metformin improves cognitive dysfunction through SIRT1/NLRP3 pathway–mediated neuroinflammation in db/db mice	12
The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration	12
Acid sphingomyelinase expression is associated with survival in resectable pancreatic ductal adenocarcinoma	12
Regulation of innate lymphoid cell by microbial metabolites	12
SMARCC1 promotes M2 macrophage polarization and reduces ferroptosis in lung cancer by activating FLOT1 transcription	12
Protective mechanisms of loquat leaf extract and ursolic acid against diabetic pro-inflammation	12
The role of the immunosuppressive PD-1/PD-L1 checkpoint pathway in the aging process and age-related diseases	11
Hypoxia drives estrogen receptor β-mediated cell growth via transcription activation in non-small cell lung cancer	11
Mitochondria targeted esculetin administration improves insulin resistance and hyperglycemia-induced atherosclerosis in db/db mice	11
Etiopathogenesis of medication-related osteonecrosis of the jaws: a review	11
The promising arsenal of ferroptosis inducers in bladder cancer	11
The oncogenic role of EIF4A3/CDC20 axis in the endometrial cancer	11
Non-coding RNAs regulating mitochondrial function in cardiovascular diseases	11
Correction to: Downregulation of microRNA-193a-3p is involved in invertebral disc degeneration by targeting MMP14	11
Correction to: Traumatic brain injury-induced downregulation of Nrf2 activates inflammatory response and apoptotic cell death	10
Peroxiredoxins in erythrocytes: far beyond the antioxidant role	10
TIPE2: a novel regulatory factor for cardiovascular-related diseases	10
NLRC3 attenuates osteoclastogenesis by limiting TNFα+ Th17 cell response in osteoporosis	10
Correction to: Antioxidative effects of polypyrimidine tract-binding protein-associated splicing factor against pathological retinal angiogenesis through promotion of mitochondrial function	10
Insufficient SIRT1 in macrophages promotes oxidative stress and inflammation during scarring	10
Periostin secreted by cancer-associated fibroblasts promotes cancer progression and drug resistance in non-small cell lung cancer	10
Inverse correlation between plasma pyrophosphate hydrolysis and early growth of abdominal aortic aneurysm: a pilot study	10
2,8-Dihydroxyadenine disrupts epithelial integrity and alters kidney cell phenotype in vitro	10
Pkhd1cyli/cyli mice have altered renal Pkhd1 mRNA processing and hormonally sensitive liver disease	10
The mechanism of the JNK signaling pathway in drug addiction	10
New CRISPR/Cas9-based Fgfr2C361Y/+ mouse model of Crouzon syndrome exhibits skull and behavioral abnormalities	10
ATF3 in atherosclerosis: a controversial transcription factor	9
New insights into macrophage subsets in atherosclerosis	9
Kinase regulation of miRNA networks in cardiometabolic disease: emerging pathways to precision therapy	9
Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers	9
SOST gene suppression stimulates osteocyte Wnt/β-catenin signaling to prevent bone resorption and attenuates particle-induced osteolysis	9
Neuroanatomical characterization of the cell adhesion molecule IgSF9b reveals localization to inhibitory and excitatory synapses in the mouse limbic system	9
Astragaloside IV inhibits the progression of hypertensive heart disease via the RXRA/PPARG/SIRT3 axis	9
Traumatic brain injury-induced disruption of the circadian clock	9
The role of ferroptosis in renal cell carcinoma: molecular mechanisms and therapeutic implications	9
Dual roles of UPRer and UPRmt in neurodegenerative diseases	9
Fibrotic microRNAs in the suppression of HSC activation and ECM deposition to facilitate the regression of hepatic fibrosis in zebrafish	9
Role of endosomal RANKL–LGR4 signaling during osteoclast differentiation	9
TFR2 p.A75V mutation aggravates liver iron overload in alcoholic liver disease via ERK pathway	9
Zinc-binding protein metallothionein 3 protects vascular smooth muscle cells from ferroptosis via blocking lysosomal degradation of GPX4	9
Umbelliferone alleviates impaired wound healing and skin barrier dysfunction in high glucose-exposed dermal fibroblasts and diabetic skins	9
A novel RBBP8(p.E281*) germline mutation is a predisposing mutation in familial hereditary cancer syndrome	9
Hereditary non-spherocytic hemolytic anemia with GPI mutations successfully treated with allogeneic hematopoietic stem cell transplantation: a first report of two cases	8
New insights into the mechanisms and therapeutic strategies of chondrocyte autophagy in osteoarthritis	8
Spinal fluid antibody profile against bacteria demonstrates intrathecal antibody production in demyelinating diseases	8
ATF4 in proximal tubules modulates kidney function and modifies the metabolome	8
Histone H3K9 methyltransferase SETDB1 overexpression correlates with pediatric high-grade gliomas progression and prognosis	8
Leucine-rich α-2 glycoprotein 1 is associated with increased mortality risk in patients with peripheral artery disease	8
Physiological and pathological effects of phase separation in the central nervous system	8
The multifaceted roles of MCAM in development, homeostasis, pathological conditions, and cancer	8
Discoidin, CUB and LCCL domain containing 2 modulates angiogenesis by inhibiting VEGF receptor 2 endocytosis in endothelial cells	8
NO/iNOS axis impact on glioma stem cells and temozolomide resistance	8

Retraction Note: Antioxidative effects of polypyrimidine tract-binding protein-associated splicing factor against pathological retinal angiogenesis through promotion of mitochondrial function	8
Emerging therapeutic targets in systemic sclerosis	7
Underlying mechanisms of epithelial splicing regulatory proteins in cancer progression	7
Identifying survival of pan-cancer patients under immunotherapy using genomic mutation signature with large sample cohorts	7
Constitutive expression of the deubiquitinating enzyme CYLD does not affect microglia phenotype or function in homeostasis and neuroinflammation	7
Gsα deficiency in macrophages promotes tumor progression via the MAPK signaling pathway	7
Sphingolipids: drivers of cardiac fibrosis and atrial fibrillation	7
Adipose-derived mesenchymal stem cells for the prevention of capsular contracture	7
Molecular determinants of thromboinflammatory activation in inflammatory bowel disease	7
WNT2B high‑expressed fibroblasts induce the fibrosis of IBD by promoting NK cells secreting IL-33	7
MicroRNAs role in telomere length maintenance and telomerase activity in tumor cells	7
Oral supplementation of melatonin attenuates the onset of alcohol-related liver disease	7
Soluble LDL-receptor is induced by TNF-α and inhibits hepatocytic clearance of LDL-cholesterol	6
Identification of a novel eighteen-gene signature of recurrent metastasis neuroblastoma	6
Kat7 accelerates osteoarthritis disease progression through the TLR4/NF-κB signaling pathway	6
Integrative multimodal transcriptomics identifies a cancer-associated fibroblast membrane signature for predicting prognosis and therapeutic response in pancreatic ductal adenocarcinoma	6
Nicotinamide riboside kinase-2 regulates metabolic adaptation in the ischemic heart	6
Systematic and quantitative analysis of stop codon readthrough in Rett syndrome nonsense mutations	6
Ferroptosis and iron metabolism drive fibroblast activation in silicosis: insights from a novel 3D lung matrix model	6
Molecular regulation of PGC-1α: from protein-protein interactions and post-translational modifications to pharmacological modulation	6
Mechanism of efferocytosis in atherosclerosis	6
Non-invasive biomarkers prognostic of decompensation events in NASH cirrhosis: a systematic literature review	6
Evaluation of circulating glypican 4 as a novel biomarker in disease – A comprehensive review	6
Mediator kinase inhibition drives myometrial stem cell differentiation and the uterine fibroid phenotype through super-enhancer reprogramming	6
CD24, NFIL3, FN1, and KLRK1 signature predicts melanoma immunotherapy response and survival	6
Eucalyptol induces osteoblast differentiation through ERK phosphorylation in vitro and in vivo	6
Longitudinal study on immunologic, lipoproteomic, and inflammatory responses indicates the safety of sequential COVID-19 vaccination	6
TFEB: a double-edged sword for tumor metastasis	6
Mechanistic complement of autosomal dominant polycystic kidney disease: the role of aquaporins	6
Measuring Neural Factor X Pathway Activity in Rodent Glioma Cell Culture and Brain Slices	6
Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome	6
A novel peptide-compound conjugate alleviates endotoxin-induced inflammation via NF-κB/MAPK modulation	6
Upregulation of glycolytic enzyme PFKFB3 by deubiquitinase OTUD4 promotes cardiac fibrosis post myocardial infarction	6
Molecular mechanisms of thalidomide effectiveness on COVID-19 patients explained: ACE2 is a new ΔNp63α target gene	6
Exercise and CD8+ T cells: mechanisms of immune modulation in antitumor responses	6
Recent updates on targeting the molecular mediators of NAFLD	6
Current knowledge of bone-derived factor osteocalcin: its role in the management and treatment of diabetes mellitus, osteoporosis, osteopetrosis and inflammatory joint diseases	6
Application of mesenchymal stem cells in ferroptosis-related diseases	6
The multiple functions of PrPC in physiological, cancer, and neurodegenerative contexts	6
The role of immunosuppressive myofibroblasts in the aging process and age-related diseases	6
FATP1-mediated fatty acid uptake in renal tubular cells as a countermeasure for hypothermia	5
Aging- and alcohol-associated spatial transcriptomic signature in mouse acute pancreatitis reveals heterogeneity of inflammation and potential pathogenic factors	5
Impact of HOMER2 frameshift extension variant on auditory function and development	5
Correction to: MiR‑30c‑1‑3p targets matrix metalloproteinase 9 involved in the rupture of abdominal aortic aneurysms	5
Cardiovascular dysfunction and altered lysosomal signaling in a murine model of acid sphingomyelinase deficiency	5
Clinical significance of mutational variants in beta and alpha genes in patients with hemoglobinopathies from two large Greek centers: a complex interplay between genotype and phenotype	5
Targeting EFEMP1 enhances chondrogenesis and inhibits hypertrophic differentiation in a spontaneous osteoarthritis mouse model	5
β-Adrenergic blockade attenuates adverse adipose tissue responses after burn	5
The crosstalk between ubiquitination and endocrine therapy	5
Predictive value of common genetic variants in idiopathic pulmonary fibrosis survival	5
High mobility group motif proteins’ role in fibrosis, inflammation, and vascular injury in systemic sclerosis	5
GSK-3α aggravates inflammation, metabolic derangement, and cardiac injury post-ischemia/reperfusion	5
The TLR/MyD88 signalling cascade in inflammation and gastric cancer: the immune regulatory network of Helicobacter pylori	5
Hepatic microtubule destabilization facilitates liver fibrosis in the mouse model of Wilson disease	5
Glis3 as a critical regulator of Pit1-lineages and renal functions	5
The role of lncRNA in the differentiation of adipose-derived stem cells: from functions to mechanism	5
Correction to: LncRNA GATA3‑AS1 promoted invasion and migration in human endometrial carcinoma by regulating the miR‑361/ARRB2 axis	5
Transcriptome profiling of human dermal MDPL fibroblasts reveals a characteristic molecular signature providing insights into pathogenic mechanisms	4
Mechanistic study of optic atrophy 1 in ischemia-reperfusion disease	4
Correction to: Evaluation of EpCAM-specific exosomal lncRNAs as potential diagnostic biomarkers for lung cancer using droplet digital PCR	4
Celastrol-loaded biomimetic nanodrug ameliorates APAP-induced liver injury through modulating macrophage polarization	4
Patient-specific effects of metformin on the hepatic metabolism in adolescents with metabolic dysfunction-associated steatotic liver disease (MASLD)	4
Role of the pioneer transcription factor GATA2 in health and disease	4
TRAP1 modulates mitochondrial biogenesis via PGC-1α/TFAM signalling pathway in colorectal cancer cells	4
NLRP7 participates in the human subcortical maternal complex and its variants cause female infertility characterized by early embryo arrest	4
Macrophage activation contributes to diabetic retinopathy	4
Blocking prokineticin receptors attenuates synovitis and joint destruction in collagen-induced arthritis	4
Genetic deficiency of CCL5 exhibits the phenotypes of HFpEF and aggravates apoptotic cardiomyopathy in HFD-induced diabetic mice	4
CD155 promotes the advancement of hepatocellular carcinoma by suppressing the p53-mediated ferroptosis via interacting with CD96	4
Transcriptional repression of lncRNA and miRNA subsets mediated by LRF during erythropoiesis	4
Oral pyrophosphate protects Abcc6-/- mice against vascular calcification induced by chronic kidney disease	4
Prosaposin in CNS health and disease, metabolic stress and exercise adaptation	4
SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?	4
Liensinine can improve vascular remodeling in hypertension through the ferroptosis-related TLR4 inflammatory pathway	4
Oxidative stress, mitochondrial dysfunction, and ferroptosis in the placenta of gestational diabetes mellitus	4
Role of non-coding RNA in immune microenvironment and anticancer therapy of gastric cancer	4
MEK inhibitor cobimetinib increases calreticulin and induces immune modulation in TNBC	4
Preclinical evaluation of [11C]CHDI-009R for quantification of mutant huntingtin aggregates	4
Exploiting the therapeutic potential of contracting skeletal muscle-released extracellular vesicles in cancer: Current insights and future directions	4
Blockade of aryl hydrocarbon receptor restricts omeprazole-induced chronic kidney disease	4
Elevation of hsa-miR-7-5p level mediated by CtBP1-p300-AP1 complex targets ATXN1 to trigger NF-κB-dependent inflammation response	4
How calorie restriction slows aging: an epigenetic perspective	4
Effects of different amosite preparations on macrophages, lung damages, and autoimmunity	4
Beyond the target: implications of Wnt pathway inhibitors on bone health	4
Correction to: Myeloid‑specific deletion of chitinase‑3‑like 1 protein ameliorates murine diet‑induced steatohepatitis progression	4