OOIR: Observatory of International Research

Papers

(The TQCC of International Journal of Clinical Pharmacology and Therapeutics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Search for nutritional and inflammatory marker ratios to predict neutropenia in FEC therapy for breast cancer: A retrospective observational study	16
Activated charcoal helps in the diagnosis of dabigatran overdose: A case study	14
Post-marketing safety concerns with montelukast: A pharmacovigilance study based on the FDA adverse event reporting system	11
Cabotegravir pharmacokinetics in Asians with and without HIV	10
Integrative treatment of the motor neuron disease amyotrophic lateral sclerosis, efficacy of pharmacotherapy, traditional Chinese medicine and importance of respiratory support, life-style, and gastro	10
Adverse reaction profile of sulfasalazine and its persistence in chronic therapy of rheumatoid arthritis and spondyloarthritis: A multicentric observational study	9
A cross-sectional study on the potential drug-drug interaction risk of COVID-19 patients in hospital	9
Rare systemic skin hyperpigmentation associated with osimertinib: A case report	9
Potential drug-drug interactions in a multi-center study of death cases of COVID-19: The significance of appropriate drug choice	9
Cardiac arrest in an adolescent following an overdose of antidepressants comprising sertraline, quetiapine fumarate, and lamotrigine: Case report	8
Effects of iguratimod in the treatment of palindromic rheumatism: Case report	8
A decision tree model for predicting high mono-N-desethylamiodarone concentrations and reducing tissue toxicity in patients with low-dose amiodarone therapy: A multicentral retrospective cohort study	8
Inflammatory cytokines, autoantibodies and salivary gland function in Sjögren’s syndrome: Effects of T. wilfordii as Hook F medical wine and tripterygium glycosides tablets	8
Research progress in targeted therapies for gastric cancer	8
Potentiation of paclitaxel-induced apoptosis in a non-small cell lung cancer model using the traditional Chinese drug huaier: Network pharmacology analysis, experimental verification, and clinical imp	7
Cost-utility analysis of pembrolizumab versus nivolumab in the treatment of metastatic colorectal cancer from the perspective of the healthcare payer	7
Network pharmacology analysis and clinical efficacy of the traditional Chinese medicine Bu-Shen-Jian-Pi. Part 2: Modulation of hypoxia, redox status, and mitochondrial protection in a neuroblastoma ce	7
Adverse event profiles of drugs used for treatment of juvenile idiopathic arthritis according to spontaneous reporting system database	7
The Enhanced Games with doping permitted and Hulk Hogan	6
Personalized management of acenocoumarol dosage using eGFR: Analysis of INR data in a cohort of 204 patients	6
Pegylated-interferon alpha (PEG-IFNα)-induced interstitial lung disease in a patient with chronic hepatitis B: A case report and literature review	5
Pharmacokinetics, safety, and bioequivalence of apixaban tablets in healthy Chinese subjects under fasting and fed conditions	5
Activated charcoal can be used to aid the diagnosis of an overdose of dabigatran etexilate	5
Factors affecting outcome in hospitalized patients treated according to recommendations from clinical pharmacologists	5
Retrospective evaluation of medical information for predicting tazobactam/piperacillin-induced liver injury	5

Deprescribing proton pump inhibitors: A study in hospitalized patients in Slovenia	5
Drug-drug interaction between remdesivir and immunosuppressant agents in a kidney transplant recipient	5
Self-reported urinary urgency in association with vitamin D and psychiatric symptoms among patients with musculoskeletal pain	5
Sodium-glucose cotransporter-2 inhibitor treatment has differential effects on the incidence of various malignancies: Evidence from a spontaneous adverse reaction database	5
Methylobacterium infection-induced peritonitis in a patient with renal insufficiency: A case report and literature review	5
High-dose ulinastatin reduces postoperative bleeding and provides platelet-protective effects in patients undergoing heart valve replacement surgery	4
Elevation of serum creatine kinase induced by anti-thyroid drugs: Two case reports and a literature review	4
Components in Prunus mume and their targets in the alleviation of severe depression identified using network pharmacology analysis	4
Evaluation of the risk factors for the failure of a single prophylactic dose of anticholinergic drugs for irinotecan-induced cholinergic symptoms	4
Bioequivalence study of two formulations of afatinib dimaleate tablets in healthy subjects under fasting conditions: A randomized, open-label, single-dose, crossover trial	4
Acute arsenic poisoning from realgar water: Case series from Guilin, China	4
Bleeding events associated with recombinant human soluble thrombomodulin, classified according to renal function, in sepsis-induced disseminated intravascular coagulation	4
Sub-therapeutic trimethoprim and sulfamethoxazole plasma concentrations during continuous venovenous hemofiltration in a patient with COVID-19 and pulmonary Pneumocystis jirovecii co-infection: A case	4
Aplastic anemia associated with osimertinib: Analysis of the FDA adverse event reporting system	4
Imipenem cilastatin sodium-associated thrombocytopenia in an older patient: A case report and literature review	4
The vancomycin dosage calculator: Prediction superiority and validation in a comparison of four algorithms using retrospective data from non-critical patients aged 18 to 59 years	4
Degree of serum LDL cholesterol reduction by simvastatin and ezetimibe is dependent on baseline LDL cholesterol concentration but not on baseline values and changes in cholesterol synthesis and absorp	4
Prediction of anti-epileptic drug response of patients based on peripheral blood RNA profiles and machine learning	4
Metformin alone and in combination with sitagliptin induces depression and impairs quality of life in type 2 diabetes mellitus patients: An observational study	4
Pharmacokinetic evaluation and relative bioavailability pilot study of fidaxomicin in healthy Chinese subjects: An open, randomized, single-dose, cross-over study	4
Simultaneous determination of cefmetazole and cefaclor in urine from pediatric patients with urinary tract infections using a newly developed high-performance liquid chromatography assay method	4
Pharmacokinetics and bioequivalence of tofacitinib 5 mg in healthy Korean male subjects	3
Pharmacokinetics and pharmacodynamics of amiodarone in patients with hypertriglyceridemia: Two case reports	3
Randomized, open-label, crossover trial comparing the pharmacokinetic profile of a novel oral aspirin solution and a chewed aspirin tablet	3
Severe autoimmune hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency as a complication of nivolumab treatment: A case report	3
Intrathecal drug-infusion system for treating pain in advanced cancer: New research in patient management	3
Is compressed colchicine tablet superior to other colchicine preparations in patients with familial Mediterranean fever?	3
Topics in focus 2025 The International Journal of Clinical Pharmacology and Therapeutics	3
Warfarin pharmacokinetics and pharmacodynamics are not affected by concomitant administration of the long-acting GLP-1 receptor agonist polyethylene glycol loxenatide	3
Semaglutide-induced transient intestinal ischemia: A case report	3
Pharmacokinetic and bioequivalence of lenalidomide in multiple myeloma patients	3
Network target theory and network pharmacology: Next generation drug research in medicine using AI models	3
Risks of malignant lymphoma in rheumatoid arthritis patients receiving methotrexate-alone and in combination therapy compared with the general population: A study based on a Japanese medical claims da	3
Clinical effects of atomizing inhalation of antibiotics on germ clearance rate and adverse reactions in respiratory infectious diseases: A meta-analysis	3
Treatment of severe psoriasis in a hospice care patient using secukinumab, an inhibitor of interleukin-17A expression: Treatment response and changes in quality of life	3
Severe genital cutaneous toxicity with sunitinib	3
Novel intravenous human IVIG in patients with secondary immunodeficiency: Interim analysis of a multicenter, prospective, non-interventional study	3
Analysis of risk factors for hypoglycemia in patients with gastrointestinal bleeding induced by somatostatin for injection and establishment of the prediction model	3
Analgesia with reduced incidence of adverse reactions using flurbiprofen axetil in combination with half standard-dose opioids in primary total knee arthroplasty	3
Adenosine-2A agonists: Positioning as functional contrast agents in diagnostic cardiology	2
Network pharmacology and bioinformatics analysis of the multi-target immune-inflammatory mechanisms of Shengma Gegen decoction in chronic urticaria	2
Ocular myasthenia gravis-like symptoms associated with erenumab: Case report	2
Pegylated liposomal doxorubicin-induced hand-foot syndrome in a patient with breast cancer: Case report and FAERS database analysis	2
Comparison of the acid suppression effects between low-dose esomeprazole and famotidine in healthy subjects	2
Effect of inhaled corticosteroid with oral montelukast and levocetirizine in asthma: A population-based study	2
Early acute kidney injury after tacrolimus administration in heart transplant recipients receiving basiliximab induction therapy	2
Evaluation of the comparative pharmacokinetic properties of a new orally disintegrating tablet of tegoprazan in healthy Korean subjects	2
Beneficial effects of dexmedetomidine with sevoflurane inhalation in abdominal surgery: Quality of anesthesia, intestinal flora, and serum pain mediators	2
Sodium-glucose cotransporter 2 (SGLT2) inhibitors, as potential (off-label) anti-obesity agents and effects on cardiovascular risk: A systematic review and meta-analysis	2
Neonatal pain score after use of paracetamol: Is there a relationship with serum trough concentration at steady state in preterm and term neonates?	2

Epithelial-mesenchymal transition biomarkers in patients with acute exacerbation of COPD are indicative of disease severity, disease progression, and risk of readmission	2
Impact of extracorporeal membrane oxygenation on antituberculosis drug concentrations: A case study and pharmaceutical care strategies	2
Subcutaneous infliximab CT-P13 without intravenous induction in psoriatic arthritis: A case report and pharmacokinetic considerations	2
Adverse reactions of PD-1/PD-L1 inhibitors in cancer: FAERS database analysis and protocols to mitigate immune-related events in elderly patients and when using pembrolizumab and atezolizumab	2
Acute myeloid leukemia after 10 years of azathioprine treatment for Crohn’s disease	2
Changes in the intestinal microbiota of patients with Parkinson’s disease and their clinical significance	2
Clinical Handbook of Psychotropic Drugs for Children and Adolescents (5th Edition)	2
A rare case of septic shock caused by Serratia marcescens in an immunocompetent male adolescent. Comment on: DOI: 10.5414/CP204652 by Mughrab et al.	2
Treatment of delayed fracture healing with Bushen Tiansui decoction: Analysis of active agents and targets using bioinformatics and network pharmacology analysis	2
Exogenous insulin antibody syndrome in type 2 diabetes with diabetic ketoacidosis: A case report and literature review	2
Bisphosphonates in combination with alendronate sodium increase bone mineral density and modulate IL-6, TNF-α, and IGF-1 in patients with osteoporosis	2
Pharmocracy via MCC to de-prescribing: The attempted ascent and descent of Everest	2
Methotrexate and folic acid supplementation in rheumatoid arthritis: A Japanese claims database and 538,985 patients from April 2015 to November 2020	2
Hemoglobin A1c levels in patients with type 2 diabetes mellitus receiving oral semaglutide with versus without proton pump inhibitors: An exploratory study	2
Longevity – via traditional Chinese medicine and macrobiotics to AI-driven network pharmacology and clinical pharmacology	2
Fondaparinux to treat cerebral venous sinus thrombosis complicated by heparin-induced thrombocytopenia during puerperium: A case report and literature review	2
Latent class analysis of patients’ background factors affecting the risk of specific adverse drug reactions to dipeptidyl peptidase 4 inhibitors	2
Evaluating real-world data in COVID-19 antigen and PCR testing	2
Prevalence of therapeutic drug monitoring and adherence to imatinib in chronic myeloid leukemia in Japan	2
A pharmacokinetic analysis of amisulpride in adult Chinese patients with schizophrenia: Impact of creatinine clearance	2
Can a β-glucan-containing orthomolecular agent (Saccharomyces sp.) containing metabolic cofactors attenuate cytokine activation and alleviate hypoxia in COVID-19 patients?	2
The triple neuromodulatory–immunomodulatory axis	2
Differentiation of bone marrow mesenchymal stem cells modulated by Bushen Tian Sui decoction via the TGF-β1-Smad2/3 signaling pathway: In vitro evidence and potential clinical application in delayed f	2