International Journal of Clinical Pharmacology and Therapeutics

Article	Citations
Search for nutritional and inflammatory marker ratios to predict neutropenia in FEC therapy for breast cancer: A retrospective observational study	12
A decision tree model for predicting high mono-N-desethylamiodarone concentrations and reducing tissue toxicity in patients with low-dose amiodarone therapy: A multicentral retrospective cohort study	10
Activated charcoal helps in the diagnosis of dabigatran overdose: A case study	10
Integrative treatment of the motor neuron disease amyotrophic lateral sclerosis, efficacy of pharmacotherapy, traditional Chinese medicine and importance of respiratory support, life-style, and gastro	9
Potential drug-drug interactions in a multi-center study of death cases of COVID-19: The significance of appropriate drug choice	8
Post-marketing safety concerns with montelukast: A pharmacovigilance study based on the FDA adverse event reporting system	8
Rare systemic skin hyperpigmentation associated with osimertinib: A case report	8
Association between ABCB1 C3435T polymorphism and antiepileptic drug resistance in epilepsy: An updated meta-analysis based on 62 studies	7
Research progress in targeted therapies for gastric cancer	7
Effects of iguratimod in the treatment of palindromic rheumatism: Case report	7
Cabotegravir pharmacokinetics in Asians with and without HIV	7
Adverse reaction profile of sulfasalazine and its persistence in chronic therapy of rheumatoid arthritis and spondyloarthritis: A multicentric observational study	7
A cross-sectional study on the potential drug-drug interaction risk of COVID-19 patients in hospital	7
Retrospective evaluation of medical information for predicting tazobactam/piperacillin-induced liver injury	6
Methylobacterium infection-induced peritonitis in a patient with renal insufficiency: A case report and literature review	6
Adverse event profiles of drugs used for treatment of juvenile idiopathic arthritis according to spontaneous reporting system database	6
Sodium-glucose cotransporter-2 inhibitor treatment has differential effects on the incidence of various malignancies: Evidence from a spontaneous adverse reaction database	6
Interferon α-induced lupus-like reaction in a mycosis fungoides patient: A case report	6
Cost-utility analysis of pembrolizumab versus nivolumab in the treatment of metastatic colorectal cancer from the perspective of the healthcare payer	6
Severe drug-induced immune hemolytic anemia due to cefmetazole: A case report	5
Personalized management of acenocoumarol dosage using eGFR: Analysis of INR data in a cohort of 204 patients	5
Deprescribing proton pump inhibitors: A study in hospitalized patients in Slovenia	5
Network pharmacology analysis and clinical efficacy of the traditional Chinese medicine Bu-Shen-Jian-Pi. Part 2: Modulation of hypoxia, redox status, and mitochondrial protection in a neuroblastoma ce	5
Factors affecting outcome in hospitalized patients treated according to recommendations from clinical pharmacologists	5
The Enhanced Games with doping permitted and Hulk Hogan	5

Pegylated-interferon alpha (PEG-IFNα)-induced interstitial lung disease in a patient with chronic hepatitis B: A case report and literature review	5
Components in Prunus mume and their targets in the alleviation of severe depression identified using network pharmacology analysis	5
Potentiation of paclitaxel-induced apoptosis in a non-small cell lung cancer model using the traditional Chinese drug huaier: Network pharmacology analysis, experimental verification, and clinical imp	5
Drug-drug interaction between remdesivir and immunosuppressant agents in a kidney transplant recipient	5
Self-reported urinary urgency in association with vitamin D and psychiatric symptoms among patients with musculoskeletal pain	5
Pharmacokinetics, safety, and bioequivalence of apixaban tablets in healthy Chinese subjects under fasting and fed conditions	5
Sub-therapeutic trimethoprim and sulfamethoxazole plasma concentrations during continuous venovenous hemofiltration in a patient with COVID-19 and pulmonary Pneumocystis jirovecii co-infection: A case	4
Evaluation of the risk factors for the failure of a single prophylactic dose of anticholinergic drugs for irinotecan-induced cholinergic symptoms	4
Activated charcoal can be used to aid the diagnosis of an overdose of dabigatran etexilate	4
COVID-19 pandemic management using the 14-day projected incidence	4
High-dose ulinastatin reduces postoperative bleeding and provides platelet-protective effects in patients undergoing heart valve replacement surgery	4
Degree of serum LDL cholesterol reduction by simvastatin and ezetimibe is dependent on baseline LDL cholesterol concentration but not on baseline values and changes in cholesterol synthesis and absorp	4
Aplastic anemia associated with osimertinib: Analysis of the FDA adverse event reporting system	4
Metformin alone and in combination with sitagliptin induces depression and impairs quality of life in type 2 diabetes mellitus patients: An observational study	4
Bleeding events associated with recombinant human soluble thrombomodulin, classified according to renal function, in sepsis-induced disseminated intravascular coagulation	4
Elevation of serum creatine kinase induced by anti-thyroid drugs: Two case reports and a literature review	4
Bioequivalence study of two formulations of afatinib dimaleate tablets in healthy subjects under fasting conditions: A randomized, open-label, single-dose, crossover trial	3
Comparative efficacy and safety of topiroxostat at different dosages in hyperuricemic patients with or without gout: A network meta-analysis of randomized controlled trials	3
Pharmacokinetic evaluation and relative bioavailability pilot study of fidaxomicin in healthy Chinese subjects: An open, randomized, single-dose, cross-over study	3
Warfarin pharmacokinetics and pharmacodynamics are not affected by concomitant administration of the long-acting GLP-1 receptor agonist polyethylene glycol loxenatide	3
Severe autoimmune hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency as a complication of nivolumab treatment: A case report	3
Hypersensitivity reaction to high-dose methotrexate and methotrexate-induced acral erythema in a child with acute lymphoblastic leukemia	3
Simultaneous determination of cefmetazole and cefaclor in urine from pediatric patients with urinary tract infections using a newly developed high-performance liquid chromatography assay method	3
Securing a diagnosis in patients presenting with suspected paracetamol (acetaminophen) poisoning: A retrospective cohort study	3
Prediction of anti-epileptic drug response of patients based on peripheral blood RNA profiles and machine learning	3
Randomized, open-label, crossover trial comparing the pharmacokinetic profile of a novel oral aspirin solution and a chewed aspirin tablet	3
Semaglutide-induced transient intestinal ischemia: A case report	3
Treatment of severe psoriasis in a hospice care patient using secukinumab, an inhibitor of interleukin-17A expression: Treatment response and changes in quality of life	3
Pharmacokinetics and pharmacodynamics of amiodarone in patients with hypertriglyceridemia: Two case reports	3
The vancomycin dosage calculator: Prediction superiority and validation in a comparison of four algorithms using retrospective data from non-critical patients aged 18 to 59 years	3
Imipenem cilastatin sodium-associated thrombocytopenia in an older patient: A case report and literature review	3
Severe genital cutaneous toxicity with sunitinib	3
Intrathecal drug-infusion system for treating pain in advanced cancer: New research in patient management	3
Pharmacokinetic and bioequivalence of lenalidomide in multiple myeloma patients	3
Clinical effects of atomizing inhalation of antibiotics on germ clearance rate and adverse reactions in respiratory infectious diseases: A meta-analysis	3
Early acute kidney injury after tacrolimus administration in heart transplant recipients receiving basiliximab induction therapy	2
A pharmacokinetic analysis of amisulpride in adult Chinese patients with schizophrenia: Impact of creatinine clearance	2
Successful management of tumor necrosis factor-alpha inhibitor-induced Sweet syndrome in a patient with ulcerative colitis: A case report	2
Acute myeloid leukemia after 10 years of azathioprine treatment for Crohn’s disease	2
Exogenous insulin antibody syndrome in type 2 diabetes with diabetic ketoacidosis: A case report and literature review	2
Analysis of risk factors for hypoglycemia in patients with gastrointestinal bleeding induced by somatostatin for injection and establishment of the prediction model	2
Association of gynecomastia with antidiabetic medications in older adults: Data mining from different national pharmacovigilance databases	2
Pegylated liposomal doxorubicin-induced hand-foot syndrome in a patient with breast cancer: Case report and FAERS database analysis	2
Bisphosphonates in combination with alendronate sodium increase bone mineral density and modulate IL-6, TNF-α, and IGF-1 in patients with osteoporosis	2
Topics in focus 2025 The International Journal of Clinical Pharmacology and Therapeutics	2
Favipiravir pharmacokinetics in COVID-19 patients with moderate to severe kidney dysfunction: Lessons learned	2
Effects of reduced edoxaban administration on bleeding risk and D-dimer levels in patients wearing elastic stockings after total hip arthroplasty: A retrospective cohort study	2
Subcutaneous infliximab CT-P13 without intravenous induction in psoriatic arthritis: A case report and pharmacokinetic considerations	2
Evaluating real-world data in COVID-19 antigen and PCR testing	2
Clinical Handbook of Psychotropic Drugs for Children and Adolescents (5th Edition)	2

Neonatal pain score after use of paracetamol: Is there a relationship with serum trough concentration at steady state in preterm and term neonates?	2
Differentiation of bone marrow mesenchymal stem cells modulated by Bushen Tian Sui decoction via the TGF-β1-Smad2/3 signaling pathway: In vitro evidence and potential clinical application in delayed f	2
Prevalence of therapeutic drug monitoring and adherence to imatinib in chronic myeloid leukemia in Japan	2
Changes in the intestinal microbiota of patients with Parkinson’s disease and their clinical significance	2
Analgesia with reduced incidence of adverse reactions using flurbiprofen axetil in combination with half standard-dose opioids in primary total knee arthroplasty	2
Is compressed colchicine tablet superior to other colchicine preparations in patients with familial Mediterranean fever?	2
Sodium-glucose cotransporter 2 (SGLT2) inhibitors, as potential (off-label) anti-obesity agents and effects on cardiovascular risk: A systematic review and meta-analysis	2
Pharmacokinetics and bioequivalence of tofacitinib 5 mg in healthy Korean male subjects	2
Epithelial-mesenchymal transition biomarkers in patients with acute exacerbation of COPD are indicative of disease severity, disease progression, and risk of readmission	2
Network pharmacology analysis and molecular docking using the Chinese herbal agent WYHX formula (according to Yan Dexin): Management of coronary artery disease	2
Comparative efficacy and safety of dotinurad, febuxostat, and benzbromarone in hyperuricemic patients with or without gout: A network meta-analysis of randomized controlled trials	2
Treatment of delayed fracture healing with Bushen Tiansui decoction: Analysis of active agents and targets using bioinformatics and network pharmacology analysis	2
A randomized, double-blind, three-arm, parallel group, single-dose phase I study to evaluate the pharmacokinetic similarity between SB12 (a proposed eculizumab biosimilar) and eculizumab (Soliris) in	2
Ocular myasthenia gravis-like symptoms associated with erenumab: Case report	2
Can a β-glucan-containing orthomolecular agent (Saccharomyces sp.) containing metabolic cofactors attenuate cytokine activation and alleviate hypoxia in COVID-19 patients?	2
Adverse reactions of PD-1/PD-L1 inhibitors in cancer: FEARS database analysis and protocols to mitigate immune-related events in elderly patients and when using pembrolizumab and atezolizumab	2
Inotersen and severe thrombocytopenia: 2 case reports and review	2
Risks of malignant lymphoma in rheumatoid arthritis patients receiving methotrexate-alone and in combination therapy compared with the general population: A study based on a Japanese medical claims da	2
Evaluation of the comparative pharmacokinetic properties of a new orally disintegrating tablet of tegoprazan in healthy Korean subjects	2
Network target theory and network pharmacology: Next generation drug research in medicine using AI models	2
A rare case of septic shock caused by Serratia marcescens in an immunocompetent male adolescent. Comment on: DOI: 10.5414/CP204652 by Mughrab et al.	2
Latent class analysis of patients’ background factors affecting the risk of specific adverse drug reactions to dipeptidyl peptidase 4 inhibitors	2
Longevity – via traditional Chinese medicine and macrobiotics to AI-driven network pharmacology and clinical pharmacology	2
Demographic and clinical characteristics of primary care patients vaccinated against COVID-19 in spring 2021	2
Comparison of the acid suppression effects between low-dose esomeprazole and famotidine in healthy subjects	2
The association between alphablockers in the treatment of benign prostatic hyperplasia and heart failure: A nationwide population-based cohort study in South Korea	2
Comparative bioavailability study with two sodium valproate tablet formulations administered under fasting conditions in healthy subjects	1
Network pharmacology analysis and clinical efficacy of the traditional Chinese medicine Bu-Shen-Jian-Pi. Part 1: Biogenic components and identification of targets and signaling pathways in amyotrophic	1
Determination of antimicrobial resistance pattern among post-operative orthopedic implant patients in a tertiary care hospital: A retrospective study	1
Monitoring of blood levels in patients administered CYP3A4 inhibitor during the maintenance phase of venetoclax administration	1
Comparison and evaluation of safety, pharmacokinetics, and pharmacodynamics of two regadenoson injections in healthy Chinese subjects	1
Primary hypertension in German children and adolescents: Low treatment rates and dominance of ACE inhibitors in an analysis of 7,482 cases for the period 2005 to 2023	1
Immune-mediated hepatitis caused by toripalimab: A case report	1
Alleviation of renal ischemia-reperfusion injury by quercetin, kaempferol, and luteolin in Shiwei Hezi pill (SHP): Network pharmacology and molecular docking analysis of a traditional Tibetan herbal a	1
Evaluation of the representativeness of the German Oncology Dynamics dataset	1
Biogenics and mitochondrial activation/protection: A therapy for hypoxic states in chronic disease?	1
Bioequivalence of tamsulosin 0.4 mg film-coated sustained-release tablet formulations in healthy subjects under fasting conditions	1
Pharmacokinetics and bioequivalence of two methylprednisolone tablet formulations in healthy Chinese subjects under fasting and fed conditions	1
Comparison of vancomycin area under the curve calculated based on Bayesian approach versus equation-based approach	1
Evidence that testosterone gel does not increase the risk of cardiovascular disease: A Mendelian randomization study of 337,159 European users	1
Application of low-dose etomidate combined with oxycodone and midazolam in endoscopic injection sclerotherapy	1
Membrane P-glycoprotein expression in lymphocytes from adult patients with refractory glomerulonephritis	1
Population pharmacokinetics of tofacitinib in patients with active ankylosing spondylitis	1
An HPLC-MS/MS method for determination of sulbactam in human plasma and its pharmacokinetic application in critically ill patients with augmented renal clearance	1
Serum potassium is a critical risk factor for cardiac arrhythmias in acute heart failure patients treated with levosimendan: A retrospective study in a cohort of 250 patients	1
Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials	1
Platelet count and dose, but not comorbidities, predict severe neutropenia in cabazitaxel-treated prostate cancer patients: A retrospective observational study	1
Piperacillin/tazobactam-induced reversible pancytopenia in a pregnant patient: A case report	1
Porcine antilymphocyte globulin versus rabbit antithymocyte globulin for intensive immunosuppressive therapy of acquired aplastic anemia: A meta-analysis and systematic review	1
Does methotrexate use increase the risk of dementia in patients with rheumatoid arthritis?	1
Brain surgeons, the Kaplan-Meier curve, and metastases blockade	1
Comparison of vasopressin-first weaning versus norepinephrine-first weaning in critically ill patients	1
Phase IV safety evaluation of voclosporin in lupus nephritis patients using the FAERS database for a 42-month period (2021 – 2024)	1
Medical diagnostic acumen and artificial intelligence	1
Inverse association between DPP-4 inhibitor use and fracture in older adults: A disproportionality analysis of the FAERS and JADER	1
Pulmonary fibrosis insights and therapy targets from disease models and administration of the lipophilic diterpene, sodium tanshinone IIA sulfonate: Review and meta-analysis	1
Evidence that anticoagulant use decreases in-hospital deaths in patients with new-onset atrial fibrillation	1
Factors associated with thrombocytopenia in patients treated with pegfilgrastim	1
H1 antihistamine-induced adverse events and time to onset: A retrospective analysis using the Japanese Adverse Drug Event Report Database	1
Trazodone-induced parkinsonism: A case report	1
Nocebo responses in randomized controlled trials of COVID-19 vaccines	1
Risk factors for infliximab-induced infusion reactions based on a retrospective study of medical information	1
Atovaquone-induced thrombocytopenia: A case report	1
Association between first-step analgesic use and cancer in patients with diabetes	1
High expression of EFNA3 in adrenocortical carcinoma and its association with prognosis	1
Effect of infusion time of intravenous acetaminophen on blood pressure in the intensive care unit	1
Neurodegenerative protection with Orgaheal medium-chain triglycerides oil: Evidence from cell cultures, enzyme inhibition studies, and measurement of antioxidant and lipid-lowering properties	1
Effect of extracorporeal anticoagulation with nafamostat mesilate and continuous renal replacement therapy on sepsis complicated with acute kidney injury	1
Association between trough plasma voriconazole concentration and adverse drug reactions in elderly patients	1
Lemborexant add-on further improves the effect of galantamine on sleepwake disorder in Alzheimer’s disease	1
Low albumin combined with low-molecular-weight heparin as risk factors for liver injury using azvudine: Evidence from an analysis of COVID-19 patients in a national prospective pharmacovigilance datab	1
Renoprotective effects of dulaglutide, a GLP-1 agonist, involving regulation of epithelial-mesenchymal transition in patients with type 2 diabetes and diabetic kidney disease	1
Efficacy of antacids for cisplatin-induced gastrointestinal symptoms in the treatment of lung cancer	1
Analysis of neutropenia as a predictive factor of the efficacy of trifluridine-tipiracil treatment	1
Network pharmacology and experimental analysis of Yudantong decoction, a multi-immunomodulator for the treatment of intractable cholestatic liver disease: Identification of active agents, molecular ta	1
Clinical and research implications of uricase knockout and renal injury	1
Palatability evaluation of orally disintegrating tablets using a visual analog scale in clinical trials	1
Risk factors for severe neutropenia in patients with cytomegalovirus infection treated with ganciclovir: A retrospective observational study	1
Augmented renal clearance in neurosurgical patients receiving vancomycin: Limited prognostic value for the duration of hospitalization, treatment course, fever, and changes in the CSF test and CRP	1
Mechanistic bottom-up estimation of passive drug absorption from the gastrointestinal tract: Comparison among primary cultured human intestinal cells, Caco-2 cells, artificial membrane, and animal sca	1

A case of a geriatric patient with thrombocytopenia after partial recovery from COVID-19	1
Evaluation of polypharmacy among chronic kidney disease patients in Egypt: A cross-sectional study	1
Can non-renal clearance and/or bioavailability of drugs be assessed reliably in renal impairment studies with oral drug administration?	1
A crossover study to evaluate the pharmacokinetics and bioequivalence of hydroxychloroquine tablets in healthy Chinese subjects	1
Efficacy and safety of antiplatelet therapy in COVID-19: Insights from a meta-analysis of randomized controlled trials	1
Predictors for non-attainment of meropenem target concentrations when treating infections in critically ill patients	1
Chronic myeloid leukemia in an ulcerative colitis patient receiving azathioprine: A case report	1
Prediction of hyperkalemia occurrence in patients using co-trimoxazole: Clinical adjustment of a Markov model	1
Advantages of an abdominal anticoagulant subcutaneous injection procedure based on a personal digital assistant and positioning card system: A clinical trial with a historical control cohort	1
Decongestants, proton pump inhibitors, and systemic antibiotics are associated with an increased occurrence of dysbiosis	1