OOIR: Observatory of International Research

Papers

(The TQCC of Matrix Biology is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Transmembrane and multiplexin collagens in development and pathobiology	60
Thrombospondin-1 promotes mechanical stress-mediated ligamentum flavum hypertrophy through the TGFβ1/Smad3 signaling pathway	58
ADAMTS6 cleaves the large latent TGFβ complex and increases the mechanotension of cells to activate TGFβ	45
Role of extracellular space and matrix remodeling in cardiac amyloidosis	43
Optic neuropathy associated with TGFβ dysregulation in mice with a glaucoma-causative mutation of ADAMTS10	43
Basement membrane structure and function: Relating biology to mechanics	40
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development	39
Beyond the matrisome: New frontiers in ECM research	37
Hyperglycemic environments directly compromise intestinal epithelial barrier function in an organoid model and hyaluronan (∼35 kDa) protects via a layilin dependent mechanism	36
Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior	36
Editorial Board	36
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage	33
Tumor and stroma COL8A1 secretion induces autocrine and paracrine progression signaling in pancreatic ductal adenocarcinoma	33
Neurocan regulates axon initial segment organization and neuronal activity	33
The dynamic kidney matrisome - is the circadian clock in control?	32
Obesity impairs skeletal muscle repair through NID-1 mediated extracellular matrix remodeling by mesenchymal progenitors	31
Basement membrane components define the microenvironment of aggregated fibroblasts in the skin and support their aggregation in vitro	30
Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing	28
Targeting the αVβ3/NgR2 pathway in neuroendocrine prostate cancer	28
Effects of hydrostatic pressure, osmotic pressure, and confinement on extracellular matrix associated responses in the nucleus pulposus cells ex vivo	27
Molecular and epigenetic ex vivo profiling of testis cancer-associated fibroblasts and their interaction with germ cell tumor cells and macrophages	27
Nanoscale characterization of collagen structural responses to in situ loading in rat Achilles tendons	27
Age related changes in hyaluronan expression leads to Meibomian gland dysfunction	26
Temporally and spatially regulated collagen XVIII isoforms are involved in ureteric tree development via the TSP1-like domain	26
Fibroblast integrin α11β1 is a collagen assembly receptor in mechanoregulated fibrillar adhesions	25

High hyaluronan binding and RHAMM expression identify an invasive and metastatic subpopulation in androgen-resistant prostate cancer cells	25
The epidermal integrin-mediated secretome regulates the skin microenvironment during tumorigenesis and repair	25
Corrigendum to “Laminin-511-functionalized fibrin gel enables in-gel proliferation of human induced pluripotent stem cells” [Matrix Biology Volume 142, December 2025, Pages 21–32]	25
Retraction Notice to “RETRACTED: The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis”	25
Dysfunctional latent transforming growth factor β activation after corneal injury in a classical Ehlers–Danlos model	25
Editorial Board	25
Tumor-associated fibrosis impairs the response to immunotherapy	25
Mitochondrial DNA mutations attenuate Bleomycin-induced dermal fibrosis by inhibiting differentiation into myofibroblasts	24
Loss of col4a1 in zebrafish recapitulates the cerebrovascular phenotypes associated with monogenic cerebral small vessel disease	24
Global, but not chondrocyte-specific, MT1-MMP deficiency in adult mice causes inflammatory arthritis	24
Hyaluronan in the pathogenesis of acute and post-acute COVID-19 infection	24
Inhibition of the MRTF-A/SRF signaling axis alleviates vocal fold scarring	24
Different molecular weights of hyaluronan research in knee osteoarthritis: A state-of-the-art review	23
Spatial localization of collagen hydroxylated proline site variation as an ancestral trait in the breast cancer microenvironment	23
The integral role of fibronectin in skeletal morphogenesis and pathogenesis	23
Peptide location fingerprinting identifies structural alterations within basement membrane components in ageing kidney	23
Tissue mechanics coevolves with fibrillar matrisomes in healthy and fibrotic tissues	23
Secreted ADAMTS-like 2 promotes myoblast differentiation by potentiating WNT signaling	23
Furin-like cleavage at the C1-C2 linker region of the ⍺3 chain is not required for collagen VI assembly	23
Matricellular protein CCN1 promotes collagen alignment and scar integrity after myocardial infarction	22
Lamellar thickness measurements in control and osteogenesis imperfecta human bone, with development of a method of automated thickness averaging to simplify quantitation	22
Sdc4 deletion perturbs intervertebral disc matrix homeostasis and promotes early osteopenia in the aging mouse spine	22
Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo	22
Liver-derived, circulating plasma fibronectin regulates trabecular bone mass and bone formation in adult male mice and its levels in sera associates with bone density in aging men	21
Mysteries of the collagen triple helix	21
George R. Martin: Pioneering matrix biologist	21
35kDa hyaluronan ameliorates ethanol driven loss of anti-microbial defense and intestinal barrier integrity in a TLR4-dependent manner	21
Lumican-mediated fibroblast differentiation in skin fibrosis	21
An integrin α3β1-CSTF3 signaling axis regulates alternative polyadenylation of Mmp9 mRNA	21
RIPK3-MLKL signaling activates mitochondrial CaMKII and drives intrarenal extracellular matrix production during CKD	20
The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-α-inhibitor regulate crosslinking of the hyaluronan matrix	20
Tonic repression of collagen I by the bradykinin receptor 2 in skin fibroblasts	20
Loss of type III collagen has limited effect on tendon healing in young adult mice	20
Editorial Board	19
Amelogenin proteolysis orchestrates functional amyloid pathways in enamel development	19
Chemotherapy treatment induces pro-invasive changes in liver ECM composition	19
Toward a rational therapeutic for elastin related disease: Key considerations for elastin based regenerative medicine strategies	19
The INSR/AKT/mTOR pathway regulates the pace of myogenesis in a syndecan-3-dependent manner	19
Collagen IV biosynthesis: Intracellular choreography of post-translational modifications	19
FAM20C and FAM20A in normal and ectopic mineralization: A focus on oro-renal syndromes	18
Remodeling of the extracellular matrix by serine proteases as a prerequisite for cancer initiation and progression	18
Editorial Board	18
LPA-induced expression of CCN2 in muscular fibro/adipogenic progenitors (FAPs): Unraveling cellular communication networks	18
Hypoxia and ascorbic acid: two interconnected microenvironmental factors driving collagen biosynthesis	18
Editorial Board	18
Mechanistic interrogation of mutation-independent disease modulators of RDEB identifies the small leucine-rich proteoglycan PRELP as a TGF-β antagonist and inhibitor of fibrosis	17
Role of syndecan-4 in angiogenesis and vasculogenic mimicry in triple negative breast cancer cells	17
What does it take to be a collagen receptor?	17
Collagen VI deposition mediates stromal T cell trapping through inhibition of T cell motility in the prostate tumor microenvironment	17
Mechanical control of breast cancer malignancy by promotion of mevalonate pathway enzyme synthesis	17

Extracellular matrix integrity regulates GABAergic plasticity in the hippocampus	16
Biomechanical and compositional basement membrane defects due to a Col4a1 mutation affect cardiac morphology and function	16
Heparan sulfate buffers the bone resorptive activity of Cathepsin K in bone homeostasis	16