OOIR: Observatory of International Research

Papers

(The TQCC of Matrix Biology is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Fibroblasts: The arbiters of extracellular matrix remodeling	75
Targeting the renin-angiotensin-aldosterone system in fibrosis	73
Sox9 deletion causes severe intervertebral disc degeneration characterized by apoptosis, matrix remodeling, and compartment-specific transcriptomic changes	64
Cardiac fibroblast activation during myocardial infarction wound healing	60
Extracellular matrix-derived peptides in tissue remodeling and fibrosis	54
Single cell RNA-sequencing reveals cellular heterogeneity and trajectories of lineage specification during murine embryonic limb development	51
TonEBP-deficiency accelerates intervertebral disc degeneration underscored by matrix remodeling, cytoskeletal rearrangements, and changes in proinflammatory gene expression	46
Spatial-omics: Novel approaches to probe cell heterogeneity and extracellular matrix biology	45
Role of hypoxia in skeletal muscle fibrosis: Synergism between hypoxia and TGF-β signaling upregulates CCN2/CTGF expression specifically in muscle fibers	43
Decorin deficiency promotes epithelial-mesenchymal transition and colon cancer metastasis	40
Accumulation of versican facilitates wound healing: Implication of its initial ADAMTS-cleavage site	40
The elephant in the lung: Integrating lineage-tracing, molecular markers, and single cell sequencing data to identify distinct fibroblast populations during lung development and regeneration	38
Basement membrane ligands initiate distinct signalling networks to direct cell shape	38
Decorin regulates cartilage pericellular matrix micromechanobiology	37
Collagen XI regulates the acquisition of collagen fibril structure, organization and functional properties in tendon	37
Tendon response to matrix unloading is determined by the patho-physiological niche	35
Regulators of cardiac fibroblast cell state	35
Collagen XII mediated cellular and extracellular mechanisms regulate establishment of tendon structure and function	35
Biglycan and chondroitin sulfate play pivotal roles in bone toughness via retaining bound water in bone mineral matrix	34
A novel ADAMTS17 variant that causes Weill-Marchesani syndrome 4 alters fibrillin-1 and collagen type I deposition in the extracellular matrix	33
Fibroblast heterogeneity and its impact on extracellular matrix and immune landscape remodeling in cancer	32
Fibronectin has multifunctional roles in posterior capsular opacification (PCO)	32
Role of collagen XII in skin homeostasis and repair	31
Role of autophagy in intervertebral disc and cartilage function: implications in health and disease	30
Cancer associated fibroblast: Mediators of tumorigenesis	29

Computational model predicts paracrine and intracellular drivers of fibroblast phenotype after myocardial infarction	29
Multimerin-2 maintains vascular stability and permeability	29
Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores	28
TBK1 (TANK-binding kinase 1)-mediated regulation of autophagy in health and disease	28
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype	27
Cardiac fibroblast diversity in health and disease	27
A novel mechanism in wound healing: Laminin 332 drives MMP9/14 activity by recruiting syndecan-1 and CD44	27
Autophagy, tissue repair, and fibrosis: a delicate balance	27
T-cell regulation of fibroblasts and cardiac fibrosis	26
Connexin43 gap junction drives fascia mobilization and repair of deep skin wounds	26
Mechanisms of procollagen and HSP47 sorting during ER-to-Golgi trafficking	25
Periostin and matrix stiffness combine to regulate myofibroblast differentiation and fibronectin synthesis during palatal healing	24
Distinct extracellular–matrix remodeling events precede symptoms of inflammation	24
Progranulin/EphA2 axis: A novel oncogenic mechanism in bladder cancer	23
Schwann cells contribute to keloid formation	23
Autophagic degradation of HAS2 in endothelial cells: A novel mechanism to regulate angiogenesis	23
The C-type lectin CD93 controls endothelial cell migration via activation of the Rho family of small GTPases	23
H-Ras activation and fibroblast-induced TGF-β signaling promote laminin-332 accumulation and invasion in cutaneous squamous cell carcinoma	22
ECM-regulation of autophagy: The yin and the yang of autophagy during wound healing	21
Calponin 1 increases cancer-associated fibroblasts-mediated matrix stiffness to promote chemoresistance in gastric cancer	21
Significance of host heparanase in promoting tumor growth and metastasis	20
Heparanase promotes myeloma stemness and in vivo tumorigenesis	20
Biglycan: A regulator of hepatorenal inflammation and autophagy	20
Citrullination as a novel posttranslational modification of matrix metalloproteinases	19
Peritoneal restoration by repurposing vitamin D inhibits ovarian cancer dissemination via blockade of the TGF-β1/thrombospondin-1 axis	19
Latent-transforming growth factor beta-binding protein-2 (LTBP-2) is required for longevity but not for development of zonular fibers	19
Scavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanisms	19
Targeting cellular stress in vitro improves osteoblast homeostasis, matrix collagen content and mineralization in two murine models of osteogenesis imperfecta	18
A functional outside-in signaling network of proteoglycans and matrix molecules regulating autophagy	18
Reciprocal integrin/integrin antagonism through kindlin-2 and Rho GTPases regulates cell cohesion and collective migration	18
Atrial fibrillation and cardiac fibrosis: A review on the potential of extracellular matrix proteins as biomarkers	18
Hypomorphic zebrafish models mimic the musculoskeletal phenotype of β4GalT7-deficient Ehlers-Danlos syndrome	17
PGC1α suppresses kidney cancer progression by inhibiting collagen-induced SNAIL expression	17
Causes and consequences of DNA damage-induced autophagy	17
Asporin, an extracellular matrix protein, is a beneficial regulator of cardiac remodeling	16
Collagen denaturation in the infarcted myocardium involves temporally distinct effects of MT1-MMP-dependent proteolysis and mechanical tension	16
Autophagy: Instructions from the extracellular matrix	16
The basement membrane in the cross-roads between the lung and kidney	16
Glypican-6 stimulates intestinal elongation by simultaneously regulating Hedgehog and non-canonical Wnt signaling	16
A novel ocular function for decorin in the aqueous humor outflow	16
Microfibrillar-associated protein 4 in health and disease	15
Multi-scale models of lung fibrosis	15
Dynamics of the lens basement membrane capsule and its interaction with connective tissue-like extracapsular matrix proteins	14
Organization of the laminin polymer node	14
Cartilage oligomeric matrix protein fine-tunes disturbed flow-induced endothelial activation and atherogenesis	14
The natural antisense transcript HAS2-AS1 regulates breast cancer cells aggressiveness independently from hyaluronan metabolism	14