OOIR: Observatory of International Research

Papers

(The TQCC of Matrix Biology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Autocrine IL-6 drives cell and extracellular matrix anisotropy in scar fibroblasts	44
Optic neuropathy associated with TGFβ dysregulation in mice with a glaucoma-causative mutation of ADAMTS10	43
The INSR/AKT/mTOR pathway regulates the pace of myogenesis in a syndecan-3-dependent manner	40
Versican provides the provisional matrix for uterine spiral artery dilation and fetal growth	39
Increased expression of the pathological O-glycosylated form of oncofetal fibronectin in the multidrug resistance phenotype of cancer cells	34
Thrombospondin-1 promotes mechanical stress-mediated ligamentum flavum hypertrophy through the TGFβ1/Smad3 signaling pathway	32
Editorial Board	30
Hyaluronan synthase 3 is protective after cardiac ischemia-reperfusion by preserving the T cell response	29
Collagen denaturation in the infarcted myocardium involves temporally distinct effects of MT1-MMP-dependent proteolysis and mechanical tension	29
Chemotherapy treatment induces pro-invasive changes in liver ECM composition	27
Role of autophagy in intervertebral disc and cartilage function: implications in health and disease	26
Heparanase 2 (Hpa2) attenuates tumor growth by inducing Sox2 expression	25
Circulating hyaluronic acid signature in CAP and ARDS – the role of pneumolysin in hyaluronic acid shedding	24
Peptide location fingerprinting identifies species- and tissue-conserved structural remodelling of proteins as a consequence of ageing and disease	22
The fibroblast hormone Endotrophin is a biomarker of mortality in chronic diseases	22
Site-specific glycosylation of proteoglycans: A revisited frontier in proteoglycan research	22
Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction	22
Lack of the myotendinous junction marker col22a1 results in posture and locomotion disabilities in zebrafish	22
Surveillance of nucleolar homeostasis and ribosome maturation by autophagy and the ubiquitin-proteasome system	21
O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development	20
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development	19
Tenascin-C targeting strategies in cancer	19
Delayed inhibition of collagen deposition by targeting bone morphogenetic protein 1 promotes recovery after spinal cord injury	19
Ameloblastin and its multifunctionality in amelogenesis: A review	19
ADAMTS6 cleaves the large latent TGFβ complex and increases the mechanotension of cells to activate TGFβ	19

Ubiquitin conjugating enzymes in the regulation of the autophagy-dependent degradation pathway	18
Shed syndecan-2 enhances colon cancer progression by increasing cooperative angiogenesis in the tumor microenvironment	18
Induction of heparanase 2 (Hpa2) expression by stress is mediated by ATF3	18
The basement membrane in the cross-roads between the lung and kidney	18
Connexin43 gap junction drives fascia mobilization and repair of deep skin wounds	17
Matricellular proteins in atherosclerosis development	16
LPA-induced expression of CCN2 in muscular fibro/adipogenic progenitors (FAPs): Unraveling cellular communication networks	16
Cell differentiation and matrix organization are differentially affected during bone formation in osteogenesis imperfecta zebrafish models with different genetic defects impacting collagen type I stru	16
Absence of TRIC-B from type XIV Osteogenesis Imperfecta osteoblasts alters cell adhesion and mitochondrial function – A multi-omics study	16
TGF-β induces matrisome pathological alterations and EMT in patient-derived prostate cancer tumoroids	16
Activation of skeletal muscle FAPs by LPA requires the Hippo signaling via the FAK pathway	16
Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis	16
Analysis of extracellular matrix network dynamics in cancer using the MatriNet database	15
Autophagy, tissue repair, and fibrosis: a delicate balance	15
Matrix stiffness increases energy efficiency of endothelial cells	15
Health consequences of mutant cartilage oligomeric matrix protein and its relationship to abnormal growth and joint degeneration	14
Modulating tenascin-C functions by targeting the MAtrix REgulating MOtif, “MAREMO”	14
Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma	14
Targeting cellular stress in vitro improves osteoblast homeostasis, matrix collagen content and mineralization in two murine models of osteogenesis imperfecta	14
Mammary collagen is under reproductive control with implications for breast cancer	14
Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice	13
Editorial Board	13
A CNA-35-based high-throughput fibrosis assay reveals ORAI1 as a regulator of collagen release from pancreatic stellate cells	13
Basement membranes in lung metastasis growth and progression	13
Remodeling of the extracellular matrix by serine proteases as a prerequisite for cancer initiation and progression	13
AβPP-tau-HAS1 axis trigger HAS1-related nuclear speckles and gene transcription in Alzheimer's disease	12
Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior	12
Unraveling the role of TGFβ signaling in thoracic aortic aneurysm and dissection using Fbn1 mutant mouse models	12
What does it take to be a collagen receptor?	12
Matrix stiffening facilitates the collective invasion of breast cancer through the periostin-integrin mechanotransduction pathway	12
Transglutaminase-mediated stiffening of the glomerular basement membrane mitigates pressure-induced reductions in molecular sieving coefficient by reducing compression	12
Heparanase 2 (Hpa2) attenuates the growth of pancreatic carcinoma	12
Editorial Board	12
Endothelial hyaluronan synthase 3 aggravates acute colitis in an experimental model of inflammatory bowel disease	12
The extracellular matrix differentially directs myoblast motility and differentiation in distinct forms of muscular dystrophy	12
Tissue inhibitors of metalloproteinases are proteolytic targets of matrix metalloproteinase 9	12
Beyond the matrisome: New frontiers in ECM research	12
An adapted passive model of anti-MPO dependent crescentic glomerulonephritis reveals matrix dysregulation and is amenable to modulation by CXCR4 inhibition	11
Targeting the αVβ3/NgR2 pathway in neuroendocrine prostate cancer	11
ECM-regulation of autophagy: The yin and the yang of autophagy during wound healing	11
Collagen VI deposition mediates stromal T cell trapping through inhibition of T cell motility in the prostate tumor microenvironment	11
Accumulation of versican and lack of versikine ameliorate acute colitis	11
Impact of vascular Ehlers-Danlos Syndrome-associated Gly substitutions on structure, function, and mechanics using bacterial collagen	10
Obesity impairs skeletal muscle repair through NID-1 mediated extracellular matrix remodeling by mesenchymal progenitors	10
The phosphorylation of serine55 in enamelin is essential for murine amelogenesis	10
Hyaluronan synthesis inhibition impairs antigen presentation and delays transplantation rejection	10
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage	10
Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease	10
Endothelial cell (EC)-specific CTGF/CCN2 Expression Increases EC Reprogramming and Atherosclerosis	10
Distinct extracellular–matrix remodeling events precede symptoms of inflammation	10