Matrix Biology

Article	Citations
Transmembrane and multiplexin collagens in development and pathobiology	56
Optic neuropathy associated with TGFβ dysregulation in mice with a glaucoma-causative mutation of ADAMTS10	56
Thrombospondin-1 promotes mechanical stress-mediated ligamentum flavum hypertrophy through the TGFβ1/Smad3 signaling pathway	44
Basement membrane structure and function: Relating biology to mechanics	41
ADAMTS6 cleaves the large latent TGFβ complex and increases the mechanotension of cells to activate TGFβ	41
Role of extracellular space and matrix remodeling in cardiac amyloidosis	39
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development	39
The dynamic kidney matrisome - is the circadian clock in control?	36
Beyond the matrisome: New frontiers in ECM research	35
Targeting the αVβ3/NgR2 pathway in neuroendocrine prostate cancer	35
Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing	35
Tumor and stroma COL8A1 secretion induces autocrine and paracrine progression signaling in pancreatic ductal adenocarcinoma	33
Basement membrane components define the microenvironment of aggregated fibroblasts in the skin and support their aggregation in vitro	33
Neurocan regulates axon initial segment organization and neuronal activity	32
Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior	32
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage	31
Hyperglycemic environments directly compromise intestinal epithelial barrier function in an organoid model and hyaluronan (∼35 kDa) protects via a layilin dependent mechanism	30
Editorial Board	30
Obesity impairs skeletal muscle repair through NID-1 mediated extracellular matrix remodeling by mesenchymal progenitors	30
Molecular and epigenetic ex vivo profiling of testis cancer-associated fibroblasts and their interaction with germ cell tumor cells and macrophages	28
The epidermal integrin-mediated secretome regulates the skin microenvironment during tumorigenesis and repair	27
Effects of hydrostatic pressure, osmotic pressure, and confinement on extracellular matrix associated responses in the nucleus pulposus cells ex vivo	27
Tumor-associated fibrosis impairs the response to immunotherapy	26
Temporally and spatially regulated collagen XVIII isoforms are involved in ureteric tree development via the TSP1-like domain	26
Age related changes in hyaluronan expression leads to Meibomian gland dysfunction	26

Nanoscale characterization of collagen structural responses to in situ loading in rat Achilles tendons	26
Dysfunctional latent transforming growth factor β activation after corneal injury in a classical Ehlers–Danlos model	25
High hyaluronan binding and RHAMM expression identify an invasive and metastatic subpopulation in androgen-resistant prostate cancer cells	25
Corrigendum to “Laminin-511-functionalized fibrin gel enables in-gel proliferation of human induced pluripotent stem cells” [Matrix Biology Volume 142, December 2025, Pages 21–32]	25
Retraction Notice to “RETRACTED: The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis”	25
Inhibition of the MRTF-A/SRF signaling axis alleviates vocal fold scarring	25
Editorial Board	25
Sdc4 deletion perturbs intervertebral disc matrix homeostasis and promotes early osteopenia in the aging mouse spine	24
Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo	24
The integral role of fibronectin in skeletal morphogenesis and pathogenesis	24
Hyaluronan in the pathogenesis of acute and post-acute COVID-19 infection	24
Furin-like cleavage at the C1-C2 linker region of the ⍺3 chain is not required for collagen VI assembly	24
Tissue mechanics coevolves with fibrillar matrisomes in healthy and fibrotic tissues	24
Fibroblast integrin α11β1 is a collagen assembly receptor in mechanoregulated fibrillar adhesions	24
Loss of col4a1 in zebrafish recapitulates the cerebrovascular phenotypes associated with monogenic cerebral small vessel disease	24
Peptide location fingerprinting identifies structural alterations within basement membrane components in ageing kidney	23
Global, but not chondrocyte-specific, MT1-MMP deficiency in adult mice causes inflammatory arthritis	23
Secreted ADAMTS-like 2 promotes myoblast differentiation by potentiating WNT signaling	23
Matricellular protein CCN1 promotes collagen alignment and scar integrity after myocardial infarction	23
Mitochondrial DNA mutations attenuate Bleomycin-induced dermal fibrosis by inhibiting differentiation into myofibroblasts	23
Lamellar thickness measurements in control and osteogenesis imperfecta human bone, with development of a method of automated thickness averaging to simplify quantitation	22
Different molecular weights of hyaluronan research in knee osteoarthritis: A state-of-the-art review	22
Spatial localization of collagen hydroxylated proline site variation as an ancestral trait in the breast cancer microenvironment	22
George R. Martin: Pioneering matrix biologist	21
Lumican-mediated fibroblast differentiation in skin fibrosis	21
The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-α-inhibitor regulate crosslinking of the hyaluronan matrix	21
RIPK3-MLKL signaling activates mitochondrial CaMKII and drives intrarenal extracellular matrix production during CKD	21
Liver-derived, circulating plasma fibronectin regulates trabecular bone mass and bone formation in adult male mice and its levels in sera associates with bone density in aging men	21
Mysteries of the collagen triple helix	21
An integrin α3β1-CSTF3 signaling axis regulates alternative polyadenylation of Mmp9 mRNA	21
35kDa hyaluronan ameliorates ethanol driven loss of anti-microbial defense and intestinal barrier integrity in a TLR4-dependent manner	20
Chemotherapy treatment induces pro-invasive changes in liver ECM composition	20
Editorial Board	20
The INSR/AKT/mTOR pathway regulates the pace of myogenesis in a syndecan-3-dependent manner	20
Tonic repression of collagen I by the bradykinin receptor 2 in skin fibroblasts	20
Amelogenin proteolysis orchestrates functional amyloid pathways in enamel development	19
Remodeling of the extracellular matrix by serine proteases as a prerequisite for cancer initiation and progression	19
Collagen IV biosynthesis: Intracellular choreography of post-translational modifications	19
Toward a rational therapeutic for elastin related disease: Key considerations for elastin based regenerative medicine strategies	19
Lack of the myotendinous junction marker col22a1 results in posture and locomotion disabilities in zebrafish	19
LPA-induced expression of CCN2 in muscular fibro/adipogenic progenitors (FAPs): Unraveling cellular communication networks	19
Editorial Board	19
FAM20C and FAM20A in normal and ectopic mineralization: A focus on oro-renal syndromes	18
Editorial Board	18
Collagen VI deposition mediates stromal T cell trapping through inhibition of T cell motility in the prostate tumor microenvironment	18
Extracellular matrix integrity regulates GABAergic plasticity in the hippocampus	18
What does it take to be a collagen receptor?	18
Mechanical control of breast cancer malignancy by promotion of mevalonate pathway enzyme synthesis	18
Scleraxis and collagen I expression increase following pilot isometric loading experiments in a rodent model of patellar tendinopathy	18
Mechanistic interrogation of mutation-independent disease modulators of RDEB identifies the small leucine-rich proteoglycan PRELP as a TGF-β antagonist and inhibitor of fibrosis	18

Biomechanical and compositional basement membrane defects due to a Col4a1 mutation affect cardiac morphology and function	18
An interview with Valerie Horsley	17
Human intestinal myofibroblasts deposited collagen VI enhances adhesiveness for T cells – A novel mechanism for maintenance of intestinal inflammation	17
Role of syndecan-4 in angiogenesis and vasculogenic mimicry in triple negative breast cancer cells	17
S100A4 a classical DAMP as a therapeutic target in fibrosis	16
C-terminally clustered UGDH hypomorphic variants reveal subtle mechanisms of cellular and developmental disruption	16
Conditional expression of endorepellin in the tumor vasculature attenuates breast cancer growth, angiogenesis and hyaluronan deposition	16
Circulating collagen type I fragments as specific biomarkers of cardiovascular outcome risk: Where are the opportunities?	16
Structural insights on perlecan and Schwartz–Jampel syndrome	16
IGF-II regulates lysyl oxidase propeptide and mediates its effects in part via basic helix-loop-helix E40	16
Fiber alignment in 3D collagen networks as a biophysical marker for cell contractility	16
SIRT4 protects against intestinal fibrosis by facilitating GLS1 degradation	16
Stiffness-responsive feedback autoregulation of DDR1 expression is mediated by a DDR1-YAP/TAZ axis	15
Fibrolamellar carcinomas–growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides	15
Controlled extracellular proteolysis of thrombospondins	15
Mmp14 is required for matrisome homeostasis and circadian rhythm in fibroblasts	15
En route towards a personalized medicine approach: Innovative therapeutic modalities for connective tissue disorders	14
Editorial Board	14
Editorial Board	14
Matrix bound nanovesicles: A great promise for TERM in less than a decade of research	14
CD45+/ Col I+ Fibrocytes: Major source of collagen in the fibrotic lung, but not in passaged fibroblast cultures	14
Cancer-associated fibroblasts promote proliferation, angiogenesis, metastasis and immunosuppression in gastric cancer	14
Involvement of lysophosphatidic acid-LPA1-YAP signaling in healthy and pathological FAPs migration	14
Loss of BTK ameliorates the pathological cardiac fibrosis and dysfunction	14
Collagen VI ablation in zebrafish causes neuromuscular defects during developmental and adult stages	14
Health consequences of mutant cartilage oligomeric matrix protein and its relationship to abnormal growth and joint degeneration	13
Cell differentiation and matrix organization are differentially affected during bone formation in osteogenesis imperfecta zebrafish models with different genetic defects impacting collagen type I stru	13
Editorial Board	13
AβPP-tau-HAS1 axis trigger HAS1-related nuclear speckles and gene transcription in Alzheimer's disease	13
Impact of vascular Ehlers-Danlos Syndrome-associated Gly substitutions on structure, function, and mechanics using bacterial collagen	13
Analysis of extracellular matrix network dynamics in cancer using the MatriNet database	13
Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction	13
Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease	13
The phosphorylation of serine55 in enamelin is essential for murine amelogenesis	13
Matrix stiffness increases energy efficiency of endothelial cells	13
Site-specific glycosylation of proteoglycans: A revisited frontier in proteoglycan research	13
Myeloid deficiency of heparan sulfate 6-O-endosulfatases impairs bone marrow hematopoiesis	13
Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2	13
Arylsulfatase I is a novel lysosomal chondroitin endosulfatase regulating endochondral ossification	13
Corrigendum to “Fibrolamellar carcinomas–growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides” [Matrix Biology 121(August 2023), 194–216]	12
Drosophila Col4a1 Glycine mutations highlight allelic heterogeneity and mechanistic pleiotropy	12
The life cycle of type IV collagen	12
Novel insights into the role of Discoidin domain receptor 2 (DDR2) in cancer progression: a new avenue of therapeutic intervention	12
Suppression of OGN in lung myofibroblasts attenuates pulmonary fibrosis by inhibiting integrin αv-mediated TGF-β/Smad pathway activation	12
Tissue-specific collagen hydroxylation at GEP/GDP triplets mediated by P4HA2	12
A role for decorin in improving motor deficits after traumatic brain injury	12
Integrins and integrin-driven secretory pathways as multi-dimensional regulators of tumor-associated macrophage recruitment and reprogramming in tumor microenvironment	11
Zebrafish col4a1 loss-of-function models mirror key neurovascular and ocular features of COL4A1/A2 syndrome and enable human variants assessment in vivo	11
Collagen diversity in human skin: Aging, wound healing, and disorders	11
Fibronectin isoforms promote postnatal skeletal development	11
Editorial Board	11
Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair	11
Editorial Board	11
Editorial Board	11
Asporin, an extracellular matrix protein, is a beneficial regulator of cardiac remodeling	11
Using load to improve tendon/ligament tissue engineering and develop novel treatments for tendinopathy	11
Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets	11
Mutant MESD links cellular stress to type I collagen aggregation in osteogenesis imperfecta type XX	11
Peritoneal restoration by repurposing vitamin D inhibits ovarian cancer dissemination via blockade of the TGF-β1/thrombospondin-1 axis	11
Calponin 1 increases cancer-associated fibroblasts-mediated matrix stiffness to promote chemoresistance in gastric cancer	11
Emilin2 fosters vascular stability by promoting pericyte recruitment	11
A lysyl oxidase-responsive collagen peptide illuminates collagen remodeling in wound healing	10
Decoding the MMP14 integrin link: Key player in the secretome landscape	10
Heparanase 2 (Hpa2) attenuates the growth of human sarcoma	10
Dual transgene amelioration of Lama2-null muscular dystrophy	10
Laminin-511-functionalized fibrin gel enables in-gel proliferation of human induced pluripotent stem cells	10
The endocytic receptor uPARAP is a regulator of extracellular thrombospondin-1	10
Dual role of enhancer of zeste homolog 2 in the regulation of ultraviolet radiation-induced matrix metalloproteinase-1 and type I procollagen expression in human dermal fibroblasts	10
Editorial Board	10
Metabolic control of collagen synthesis	10
Editorial Board	9
Cytokine Conversations: Fibroblasts Shape Macrophage Identity to Enhance Collagen Clearance	9
Versican provides the provisional matrix for uterine spiral artery dilation and fetal growth	9
Alterations in the microenvironment of junctional epidermolysis bullosa keratinocytes: A gene expression study	9
The gelatinases, matrix metalloproteinases 2 and 9, play individual roles in skeleton development	9
Hedgehog signaling orchestrates cartilage-to-bone transition independently of Smoothened	9
Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice	8
Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma	8
Basement membranes in lung metastasis growth and progression	8
Laminin γ1 chain is essential for the cardiorespiratory and muscular systems	8

TGF-β induces matrisome pathological alterations and EMT in patient-derived prostate cancer tumoroids	8
Increased expression of the pathological O-glycosylated form of oncofetal fibronectin in the multidrug resistance phenotype of cancer cells	8
Hyaluronan synthase 3 is protective after cardiac ischemia-reperfusion by preserving the T cell response	8
Activation of skeletal muscle FAPs by LPA requires the Hippo signaling via the FAK pathway	8