OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Gastroenterology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Revisiting the relationship between thyroid function and metabolic dysfunction-associated steatotic liver disease in the era of resmetirom	187
Three-dimensional chromatin landscapes in hepatocellular carcinoma associated with hepatitis B virus	100
Managing radiation safety and protection in gastroenterology in Japan: insights from the REX-GI study	91
High-risk population of progressive hepatic fibrosis in chronic hepatitis B patients on antiviral therapy	82
Alpha-fetoprotein combined with initial tumor shape irregularity in predicting the survival of patients with advanced hepatocellular carcinoma treated with immune-checkpoint inhibitors: a retrospectiv	67
Clinical features and oncological outcomes of intestinal cancers associated with ulcerative colitis and Crohn’s disease	65
Ratio of submucosal thickness to total bowel wall thickness as a new sonographic parameter to estimate endoscopic remission of ulcerative colitis	59
Integrated analysis of tertiary lymphoid structures in relation to tumor-infiltrating lymphocytes and patient survival in pancreatic ductal adenocarcinoma	59
Risk of gastric and oesophageal adenocarcinoma following discontinuation of long-term proton-pump inhibitor therapy	58
Correlation between mismatch repair and survival of patients with gastric cancer after 5-FU-based adjuvant chemotherapy	54
Bifidobacterium bifidum CIP-01 attenuates metabolic dysfunction-associated steatotic liver disease induced by high-alcohol-producing Klebsiella pneumoniae	52
Artificial intelligence (AI) models for the ultrasonographic diagnosis of liver tumors and comparison of diagnostic accuracies between AI and human experts	51
Corynoline protects chronic pancreatitis via binding to PSMA2 and alleviating pancreatic fibrosis	46
Non-alcoholic fatty liver disease in patients with morbid obesity: the gut microbiota axis as a potential pathophysiology mechanism	45
Induction of ferroptosis by photodynamic therapy and enhancement of antitumor effect with ferroptosis inducers	40
Predictive factors for the progression of primary localized stage small-bowel follicular lymphoma	38
Reply to: Minocycline versus tetracycline in bismuth-containing quadruple therapy for Helicobacter pylori rescue treatment: a multicentre, randomized controlled trial	37
Clinicopathological features and prognosis of primary small bowel adenocarcinoma: a large multicenter analysis of the JSCCR database in Japan	35
Successful induction of human chemically induced liver progenitors with small molecules from damaged liver	33
Novel subharmonic-aided pressure estimation for identifying high-risk esophagogastric varices	33
Immunity in digestive diseases: new drugs for inflammatory bowel disease treatment—insights from Phase II and III trials	32
Induction therapy with hepatic arterial infusion chemotherapy enhances the efficacy of lenvatinib and pd1 inhibitors in treating hepatocellular carcinoma patients with portal vein tumor thrombosis	32
Associations between excessive supragastric belching and esophageal reflux factors in patients with PPI-refractory GERD in Japan	30
Clinical practice guidelines for duodenal cancer 2021	29
Clinical factors to predict changes of esophagogastric varices after sustained viral response with direct-acting antiviral therapy	29

Association between homologous recombination deficiency and time to treatment failure to platinum-based chemotherapy for pancreatic cancer by using the C-CAT database	29
Considerations for evaluating antibiotic prophylaxis in cirrhotic patients with upper gastrointestinal bleeding in real-world data	29
Hic-5 deficiency attenuates MAFLD by inhibiting neutrophils migration via the CXCL1-CXCR2 axis	28
The absence of warfarin treatment and situs inversus are associated with the occurrence of hepatocellular carcinoma after Fontan surgery	28
Correction: Fungal mycobiome dysbiosis in choledocholithiasis concurrent with cholangitis	27
Evaluation of cholecystectomy in older individuals using real-world data: a multilevel analysis based on a nationwide administrative database in Japan	26
Acknowledgements	26
Persistent body-weight change on achalasia and peroral endoscopic myotomy: a multicenter cohort study	26
Current status and trends in ERCP and post-ERCP pancreatitis in Japan: a nationwide observational study	25
A study for every second day administration of vonoprazan for maintenance treatment of erosive GERD (ESD von GERD): a multicenter randomized cross-over study	25
Anxiety and behavioral changes in Japanese patients with inflammatory bowel disease due to COVID-19 pandemic: a national survey	25
Optimising carotegrast methyl use in ulcerative colitis: patient profiling, predictive biomarkers, and timing of efficacy evaluation (ASPECT study)	24
Body mass index and survival among patients with advanced biliary tract cancer: a single-institutional study with nationwide data-based validation	24
Expert consensus on vaccination in patients with inflammatory bowel disease in Japan	23
Trends of hepatitis B virus genotype distribution in chronic hepatitis B patients in Japan	23
What is the appropriate method of pathological specimen collection for cholangiocarcinoma detection in primary sclerosing cholangitis?	23
Alcohol-associated liver disease increases the risk of muscle loss and mortality in patients with cirrhosis	23
Nationwide cohort study identifies clinical outcomes of angioectasia in patients with acute hematochezia	22
Is it necessary for endoscopic surveillance for achalasia patients?	22
Treatment escalation and de-escalation decisions in Crohn’s disease: Delphi consensus recommendations from Japan, 2021	22
Proton pump inhibitor use and risk of pneumonia: a self-controlled case series study	21
Ursodeoxycholic acid for the prevention of gallstones and subsequent cholecystectomy after bariatric surgery: a meta-analysis of randomized controlled trials	21
Targeting autophagy as a therapeutic strategy against pancreatic cancer	20
Real-world efficacy and safety of glecaprevir/pibrentasvir in Japanese adolescents with chronic hepatitis C: a prospective multicenter study	20
Circulating miR-485-3p as a biomarker for VEGF-associated therapeutic response to atezolizumab plus bevacizumab in hepatocellular carcinoma	20
Clinicopathological features and prognosis of metastatic tumors in the small bowel: a large multicenter analysis of the JSCCR database in Japan	19
Utility of artificial intelligence with deep learning of hematoxylin and eosin-stained whole slide images to predict lymph node metastasis in T1 colorectal cancer using endoscopically resected specime	19
Discrepancies in reported gastrointestinal symptoms in Japanese hospitalized patients with COVID-19	19
Reply to “Considerations for evaluating antibiotic prophylaxis in cirrhotic patients with upper gastrointestinal bleeding in real-world data”	19
Gastric cancer and genomics: review of literature	18
VPS45 promotes the progression of hepatocellular carcinoma by recycling β1 integrin to the cell membrane via the endocytic pathway	18
“Pathologist-independent” strategy for T1 colorectal cancer after endoscopic resection	18
Interim analysis of a multicenter registry study of COVID-19 patients with inflammatory bowel disease in Japan (J-COSMOS)	18
Clinical trajectory of intraductal papillary mucinous neoplasms progressing to pancreatic carcinomas during long-term surveillance: a prospective series of 100 carcinoma cases	18
RTP4 silencing provokes tumor-intrinsic resistance to immune checkpoint blockade in colorectal cancer	18
Reply to “promising modality for severe ulcerative colitis: infliximab and plant-based diet as first-line (IPF) therapy”	17
Characteristics, outcomes, and risk factors of surgery for acute lower gastrointestinal bleeding: nationwide cohort study of 10,342 hematochezia cases	17
Cancer pathways in serrated polyposis syndrome: is conventional more crucial than serrated?	17
Identification of novel plasma proteins as promising noninvasive biomarker for early diagnosis and surveillance of pancreatic ductal adenocarcinoma	16
Molecular imaging of gastrointestinal stromal tumor using anti-c-KIT antibody and its fragments	16
The epidemiology of rare types of hepatobiliary and pancreatic cancer from national cancer registry	16
Correction: Partial splenic embolization combined with endoscopic therapies and vasoconstrictive drugs reduces rebleeding in cirrhosis patients with acute variceal bleeding and hypersplenism: a multic	16
Quantitative measurements of M2BPGi depend on liver fibrosis and inflammation	16
Effect of blood product transfusion on the prognosis of patients undergoing hepatectomy for hepatocellular carcinoma: a propensity score matching analysis	15
Standard versus delayed initiation of S-1 adjuvant chemotherapy after surgery for pancreatic cancer: a secondary analysis of a nationwide cohort by the Japan Pancreas Society	15
Impact of ursodeoxycholic acid treatment on Fontan-associated liver disease	15
Frequency of lymph node metastasis according to tumor location in clinical T1 early gastric cancer: supplementary analysis of the Japan Clinical Oncology Group study (JCOG0912)	15
Current status of primary liver cancer and decompensated cirrhosis in Japan: launch of a nationwide registry for advanced liver diseases (REAL)	15
Nationwide estimates of patient numbers and prevalence rates of ulcerative colitis and Crohn’s disease in Japan in 2023	15
AI-assisted diagnosis of Helicobacter pylori infection: strengths, limitations, and future directions	14

Risk of gastric and oesophageal adenocarcinomas following discontinuation of long-term proton-pump inhibitor therapy	14
The role of stromal BMP/CXCL12 signaling axis in serrated polyp development	14
Correction: Urinary dipeptidase 1 and trefoil factor 1 are promising biomarkers for early diagnosis of colorectal cancer	14
The external validation of Dallas Steatosis Index among Asian population: a useful tool for metabolic dysfunction-associated steatotic liver disease identification and prevention	14
Correction to: Composite detection rate as an upper gastrointestinal endoscopy quality measure correlating with detection of neoplasia	14
Validation of novel scoring systems for acute decompensated cirrhosis identifies PBC as an independent poor prognostic factor: a single-center Japanese cohort study	13
Development of a novel oncolytic adenovirus controlled by CDX2 promoter for esophageal adenocarcinoma therapy	13
Clinical outcome after cessation of nucleos(t)ide analog treatment in chronic hepatitis B patients who achieved HBsAg seroclearance	13
Adjuvant immune checkpoint inhibitors associated with higher recurrence-free survival in postoperative hepatocellular carcinoma (PREVENT): a prospective, multicentric cohort study	13
Post-marketing surveillance of tofacitinib in patients with ulcerative colitis in Japan: a final report of safety and effectiveness data	13
Prevalence of colonoscopy in Japan using a large-scale health claims data compared to esophagogastroduodenoscopy	13
Efficacy of endoscopic ultrasound-guided tissue acquisition for solid pancreatic lesions 20 mm or less in diameter suspected as neuroendocrine tumors or requiring differentiation	13
Renal manifestations in inflammatory bowel disease: a systematic review	13
Efficacy, tolerability, and safety of oral sulfate tablet versus 2 L-polyethylene glycol/ascorbate for bowel preparation in older patients: prospective, multicenter, investigator single-blinded, rando	13
Serum zinc levels as predictors of covert hepatic encephalopathy in patients with liver cirrhosis	13
A review on the current status and definitions of activity indices in inflammatory bowel disease: how to use indices for precise evaluation	13
Novel scale for evaluating the therapeutic efficacy of per-oral endoscopic myotomy in achalasia	13
Clinical development of a blood biomarker using apolipoprotein-A2 isoforms for early detection of pancreatic cancer	12
Acute kidney injury development is associated with mortality in Japanese patients with cirrhosis: impact of amino acid imbalance	12
Definitive-dose adjuvant radiotherapy following endoscopic submucosal dissection for superficial esophageal cancer	12
The biochemical pattern defines MASLD phenotypes linked to distinct histology and prognosis	12
Publisher Correction: Anti-integrin αvβ6 antibody as a biomarker for diagnosing ulcerative colitis: a nationwide multicenter validation study	12
Treatment strategy after noncurative endoscopic resection for early gastric cancers in patients aged ≥ 85 years: a multicenter retrospective study in a highly aged area of Japan	12
Correction: Nrf2/ASPM axis regulated vasculogenic mimicry formation in hepatocellular carcinoma under hypoxia	12
Nrf2/ASPM axis regulated vasculogenic mimicry formation in hepatocellular carcinoma under hypoxia	12
Characteristics of colorectal neuroendocrine tumors in patients prospectively enrolled in a Japanese multicenter study: a first report from the C-NET STUDY	12
Acknowledgements	12
Anti-integrin αvβ6 antibody as a biomarker for diagnosing ulcerative colitis: a nationwide multicenter validation study	11
Serum IL-6 concentration is a useful biomarker to predict the efficacy of atezolizumab plus bevacizumab in patients with hepatocellular carcinoma	11
Correction to: Epigenetic regulation of pancreatic adenocarcinoma in the era of cancer immunotherapy	11
Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-pathway	11
The antiferroptotic effect of indigo on ulcerative colitis	11
Pro- and anti-inflammatory roles of interleukin (IL)-33, IL-36, and IL-38 in inflammatory bowel disease	11
Anti-integrin αvβ6 autoantibodies in patients with primary sclerosing cholangitis	11
Urinary dipeptidase 1 and trefoil factor 1 are promising biomarkers for early diagnosis of colorectal cancer	11
Current status of type 1 (IgG4-related) autoimmune pancreatitis	11
Proposal of discontinuation criteria of atezolizumab plus bevacizumab after curative conversion therapy for unresectable early-to-intermediate-stage hepatocellular carcinoma: a multicenter proof-of-co	11
Response to letter to the editor regarding: “Alcohol-associated liver disease increases the risk of muscle reduction and mortality in patients with cirrhosis”	11
Estimating cancer risk in immune-mediated inflammatory diseases exposed to varying doses of tumour necrosis factor inhibitors	11
Metabolic dysfunction-associated steatotic liver disease affects the development of hepatocellular carcinoma after sustained virologic response in chronic hepatitis C patients	11
Reply to “Discrepancies in reported gastrointestinal symptoms in Japanese hospitalized patients with COVID-19”	10
Posttreatment serum CXCL10 level stratifies survival in compensated and decompensated cirrhotic patients due to chronic hepatitis C virus infection after direct-acting antiviral therapy	10
Letter to "The potential of an artificial intelligence for diagnosing MRI images in rectal cancer: multicenter collaborative trial"	10
FGFR2 fusions assessed by NGS, FISH, and immunohistochemistry in intrahepatic cholangiocarcinoma	10
The impact of the COVID-19 pandemic on the diagnosis, stage, and treatment of esophagogastric cancer	10
Activating KRAS and GNAS mutations in heterotopic submucosal glands of the stomach	10
Publisher Correction: CRAFITY score as a predictive marker for refractoriness to atezolizumab plus bevacizumab therapy in hepatocellular carcinoma: a multicenter retrospective study	9
Cost–utility analysis of treatment strategies for chronic constipation in Japan	9
Acknowledgements	9
Cost-effectiveness analysis of nivolumab plus chemotherapy vs chemotherapy for patients with unresectable advanced or metastatic HER2-negative gastric or gastroesophageal junction or esophageal adenoc	9
Predictors of lymph node metastases, recurrence, and survival in patients with pedunculated-type T1 colorectal cancer	9
Correction to: Clinical guidelines for primary sclerosing cholangitis 2017	9
Single-cell transcriptomics reveals hypoxia-driven iCAF_PLAU is associated with stemness and immunosuppression in anorectal malignant melanoma	9
Change in systemic steroid use and surgery rate in patients with inflammatory bowel disease: a Japanese real-world database analysis	9
Growing evidence on the highly sensitive iTACT assay of hepatitis B core-related antigen for predicting hepatitis B virus reactivation	9
Optimal direct oral anticoagulant for upper gastrointestinal endoscopic submucosal dissection	9
Development of a capsule endoscopy scoring system for the early diagnosis of small bowel Crohn’s disease	9
Serum FGF19 combined with GGT and other biomarkers predicted native liver survival following Kasai portoenterostomy in early biliary atresia	9
Global, regional, and national burden of liver cancer due to non-alcoholic steatohepatitis, 1990–2019: a decomposition and age–period–cohort analysis	9
Association of ulcerative colitis symptom severity and proctocolectomy with multidimensional patient-reported outcomes: a cross-sectional study	9
Clarifying diagnostic scope and future perspectives in AI-assisted diagnosis of Helicobacter pylori infection	9
Posttreatment liver function, but not baseline liver function stratifies patient survival after direct-acting antiviral treatment in decompensated cirrhosis with hepatitis C virus	9