OOIR: Observatory of International Research

Papers

(The H4-Index of European Journal of Pharmaceutics and Biopharmaceutics is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Editorial Board	144
Authors’ reply to comments on “Improved photostability, solubility, hygroscopic stability and antimicrobial activity of fleroxacin by synthesis of fleroxacin-D-tartaric acid pharmaceutical salt”	141
Editorial Board	126
Editorial Board	123
Long-term exposure in high viscous microenvironment facilitates acquired drug resistance of colon cancer cells to doxorubicin	108
Unravelling the polysorbate 20 composition: A fusion of UPLC-MS analysis and stochastic modelling	97
Corrigendum to “Extracellular vesicles delivered rapamycin to improve the tumor microenvironment and enhance hepatocellular carcinoma immunotherapy” [Eur. J. Pharm. Biopharm. 211 (2025) 114714]	90
Towards a population pharmacokinetic/pharmacodynamic model of anti-VEGF therapy in patients with age-related macular degeneration	79
Viscosity increase/gelation of therapeutic IgG monoclonal antibodies induced by Zn2+: One possible root cause of clogging of staked-in-needle prefilled syringes	74
Paradoxical cell targeting of calreticulin-empowered, protein-only nanoparticles	65
COSMO models for the pharmaceutical development of parenteral drug formulations	63
In-situ sequential crystallization of fenofibrate and tristearin – Understanding the distribution of API in particles and stability of solid lipid microparticles from the perspective of crystallizatio	52
Liquid crystal phase formation and non-Newtonian behavior of oligonucleotide formulations	52
Porous hydroxyapatite carrier enables localized and sustained delivery of honokiol for glioma treatment	50
Mechanisms of polysorbate 80 oxidation: Acetate and Fe(III) mediated near UV and visible light degradation enhanced by free fatty acids	48
Impact of various factors on the kinetics of non-enzymatic fragmentation of a monoclonal antibody	47
Topical liquid formulation of bacteriophages for metered-dose spray delivery	47
A comparative study of gellan gum and xanthan gum versus commercial vehicles as pharmaceutical thickening agents in oral suspensions	47
Impact of post approval quantitative changes in excipient composition on nitrosamine formation: De-risking strategy	46
Homogeneity and mechanical properties of orodispersible films loaded with pellets	44
Strain- and species-specific immune responses to human adipose stem cell-derived extracellular vesicles: A comparative pharmacological evaluation in mice and human PBMCs	44
Harnessing dicarboxylate-based salts for enhancing the performance of amorphous solid dispersions: The case of olanzapine	43
Microneedle-based two-step transdermal delivery of Langerhans cell-targeting immunoliposomes induces a Th1-biased immune response	42
Rationalisation of the purification process for a phage active pharmaceutical ingredient	41
Design and optimization of metformin-loaded solid lipid nanoparticles for neuroprotective effects in a rat model of diffuse traumatic brain injury: A biochemical, behavioral, and histological study	41

Double-layer dissolving microneedles for delivery of mesenchymal stem cell Secretome: Formulation, characterisation and skin irritation study	40
Question-based review for pharmaceutical development: An enhanced quality approach	40
Less is more: Self-amplifying mRNA becomes self-killing upon dose escalation in immune-competent retinal cells	39
Comparison of barrier properties of outer blood-retinal barrier models – Human stem cell-based models as a novel tool for ocular drug discovery	39
Physiologically based biopharmaceutics modeling of regional and colon absorption in humans	38
Effect of the combination of ion-pairs strategies and permeation enhancers on iguratimod transdermal patch against rheumatoid arthritis	37
Nose-to-Brain delivery of genistein-loaded peppermint lipid nanocapsules for neuroprotection against Alzheimer’s Disease: Formulation, Characterization, pharmacokinetic and Pharmacodynamic studies	37
Release profiles prediction of diclofenac sodium patches using Raman mapping technique	37
Editorial Board	37
Formulation strategies to provide oxygen-release to contrast local hypoxia for transplanted islets	36
Metal complex lipid-based nanoparticles deliver metabolism-regulating lomitapide to overcome CTC immune evasion via activating STING pathway	35