OOIR: Observatory of International Research

Papers

(The H4-Index of European Journal of Pharmaceutics and Biopharmaceutics is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Editorial Board	125
Authors’ reply to comments on “Improved photostability, solubility, hygroscopic stability and antimicrobial activity of fleroxacin by synthesis of fleroxacin-D-tartaric acid pharmaceutical salt”	124
Comparison of barrier properties of outer blood-retinal barrier models – Human stem cell-based models as a novel tool for ocular drug discovery	116
A comparative study of gellan gum and xanthan gum versus commercial vehicles as pharmaceutical thickening agents in oral suspensions	116
Design and optimization of metformin-loaded solid lipid nanoparticles for neuroprotective effects in a rat model of diffuse traumatic brain injury: A biochemical, behavioral, and histological study	98
Double-layer dissolving microneedles for delivery of mesenchymal stem cell Secretome: Formulation, characterisation and skin irritation study	92
Editorial Board	86
Editorial Board	75
Long-term exposure in high viscous microenvironment facilitates acquired drug resistance of colon cancer cells to doxorubicin	68
Microneedle-based two-step transdermal delivery of Langerhans cell-targeting immunoliposomes induces a Th1-biased immune response	58
Unravelling the polysorbate 20 composition: A fusion of UPLC-MS analysis and stochastic modelling	57
Corrigendum to “Extracellular vesicles delivered rapamycin to improve the tumor microenvironment and enhance hepatocellular carcinoma immunotherapy” [Eur. J. Pharm. Biopharm. 211 (2025) 114714]	55
Towards a population pharmacokinetic/pharmacodynamic model of anti-VEGF therapy in patients with age-related macular degeneration	51
Viscosity increase/gelation of therapeutic IgG monoclonal antibodies induced by Zn2+: One possible root cause of clogging of staked-in-needle prefilled syringes	49
Less is more: Self-amplifying mRNA becomes self-killing upon dose escalation in immune-competent retinal cells	48
Simplified choice of suitable excipients within biologics formulation design using protein-protein interaction- and water activity-maps	47
Strain- and species-specific immune responses to human adipose stem cell-derived extracellular vesicles: A comparative pharmacological evaluation in mice and human PBMCs	46
Rationalisation of the purification process for a phage active pharmaceutical ingredient	45
Paradoxical cell targeting of calreticulin-empowered, protein-only nanoparticles	44
COSMO models for the pharmaceutical development of parenteral drug formulations	44
Liquid crystal phase formation and non-Newtonian behavior of oligonucleotide formulations	43
Mechanisms of polysorbate 80 oxidation: Acetate and Fe(III) mediated near UV and visible light degradation enhanced by free fatty acids	42
In-situ sequential crystallization of fenofibrate and tristearin – Understanding the distribution of API in particles and stability of solid lipid microparticles from the perspective of crystallizatio	42
Topical liquid formulation of bacteriophages for metered-dose spray delivery	40
Porous hydroxyapatite carrier enables localized and sustained delivery of honokiol for glioma treatment	39

Homogeneity and mechanical properties of orodispersible films loaded with pellets	38
Impact of post approval quantitative changes in excipient composition on nitrosamine formation: De-risking strategy	38
Impact of various factors on the kinetics of non-enzymatic fragmentation of a monoclonal antibody	38
Harnessing dicarboxylate-based salts for enhancing the performance of amorphous solid dispersions: The case of olanzapine	38
Physiologically based biopharmaceutics modeling of regional and colon absorption in humans	36
Editorial Board	36
Question-based review for pharmaceutical development: An enhanced quality approach	36
Nose-to-Brain delivery of genistein-loaded peppermint lipid nanocapsules for neuroprotection against Alzheimer’s Disease: Formulation, Characterization, pharmacokinetic and Pharmacodynamic studies	36
Stearic acid-capped mesoporous silica microparticles as novel needle-like-structured drug delivery carriers	35
Effect of the combination of ion-pairs strategies and permeation enhancers on iguratimod transdermal patch against rheumatoid arthritis	35
Release profiles prediction of diclofenac sodium patches using Raman mapping technique	35