OOIR: Observatory of International Research

Papers

(The H4-Index of European Journal of Pharmaceutics and Biopharmaceutics is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Comparison of barrier properties of outer blood-retinal barrier models – Human stem cell-based models as a novel tool for ocular drug discovery	133
Impact of various factors on the kinetics of non-enzymatic fragmentation of a monoclonal antibody	109
Editorial Board	84
Simplified choice of suitable excipients within biologics formulation design using protein-protein interaction- and water activity-maps	82
Authors’ reply to comments on “Improved photostability, solubility, hygroscopic stability and antimicrobial activity of fleroxacin by synthesis of fleroxacin-D-tartaric acid pharmaceutical salt”	78
In-situ sequential crystallization of fenofibrate and tristearin – Understanding the distribution of API in particles and stability of solid lipid microparticles from the perspective of crystallizatio	76
Topical liquid formulation of bacteriophages for metered-dose spray delivery	76
Rationalisation of the purification process for a phage active pharmaceutical ingredient	72
Paradoxical cell targeting of calreticulin-empowered, protein-only nanoparticles	70
Liquid crystal phase formation and non-Newtonian behavior of oligonucleotide formulations	69
COSMO models for the pharmaceutical development of parenteral drug formulations	67
Exploiting a Rose Bengal-bearing, oxygen-producing nanoparticle for SDT and associated immune-mediated therapeutic effects in the treatment of pancreatic cancer	66
Editorial Board	64
Editorial Board	61
Editorial Board	59
Viscosity increase/gelation of therapeutic IgG monoclonal antibodies induced by Zn2+: One possible root cause of clogging of staked-in-needle prefilled syringes	58
Microneedle-based two-step transdermal delivery of Langerhans cell-targeting immunoliposomes induces a Th1-biased immune response	56
A comparative study of gellan gum and xanthan gum versus commercial vehicles as pharmaceutical thickening agents in oral suspensions	56
Key factors governing the reconstitution time of high concentration lyophilized protein formulations	55
Design, development and in-vitro/in-vivo evaluation of intranasally delivered Rivastigmine and N-Acetyl Cysteine loaded bifunctional niosomes for applications in combinative treatment of Alzheimer’s d	52
Porous hydroxyapatite carrier enables localized and sustained delivery of honokiol for glioma treatment	52
Homogeneity and mechanical properties of orodispersible films loaded with pellets	52
Physiologically based biopharmaceutics modeling of regional and colon absorption in humans	51
Less is more: Self-amplifying mRNA becomes self-killing upon dose escalation in immune-competent retinal cells	51
Double-layer dissolving microneedles for delivery of mesenchymal stem cell Secretome: Formulation, characterisation and skin irritation study	48

Towards a population pharmacokinetic/pharmacodynamic model of anti-VEGF therapy in patients with age-related macular degeneration	47
Question-based review for pharmaceutical development: An enhanced quality approach	46
Design and optimization of metformin-loaded solid lipid nanoparticles for neuroprotective effects in a rat model of diffuse traumatic brain injury: A biochemical, behavioral, and histological study	45
Palmitic acid-modified human serum albumin paclitaxel nanoparticles targeting tumor and macrophages against breast cancer	44
In vitro behavior of dronedarone hydrochloride loaded pellets using vacuum impregnation technique	42
Comparing freeze drying and spray drying of interleukins using model protein CXCL8 and its variants	40
A review of paediatric injectable drug delivery to inform the study of product acceptability – An introduction	39
Photo-induced site-specific oxidative fragmentation of IgG1 mediated by iron(III)-containing histidine buffer: Mechanistic studies and excipient effects	37
Tacrolimus and paclitaxel co-loaded O/O ointment without surfactant: Synergistic combinations for the treatment of psoriasis	37
Exosome-loaded hydrogels: A new cell-free therapeutic approach for skin regeneration	36
Development of an immunosuppressed orthotopic hepatocellular carcinoma rat model for the evaluation of chemo- and radioembolization therapies	35
Co-axial electrosprayed RAD001-loaded polycaprolactone/polyvinyl alcohol core–shell particles for treating pediatric brain tumours	35