OOIR: Observatory of International Research

Papers

(The TQCC of Amino Acids is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
BamA-targeted antimicrobial peptide design for enhanced efficacy and reduced toxicity	91
Molecular binding mechanism and novel antidiabetic and anti-hypertensive bioactive peptides from fermented camel milk with anti-inflammatory activity in raw macrophages cell lines	83
Effects of maternal branched-chain amino acid and alanine supplementation on growth and biomarkers of protein metabolism in dams fed a low-protein diet and their offspring	74
Dietary L-arginine supplementation increases the hepatic expression of AMP-activated protein kinase in rats	64
Human cell receptors: potential drug targets to combat COVID-19	60
Reply to homocysteine and copper ions: is their interaction responsible for cardiovascular‑related damage?	58
Proline oxidase silencing inhibits p53-dependent apoptosis in MCF-7 breast cancer cells	57
Cortisol enhances citrulline synthesis from proline in enterocytes of suckling piglets	56
Oral anserine supplementation does not attenuate type-2 diabetes or diabetic nephropathy in BTBR ob/ob mice	54
Screening of AS101 analog, organotellurolate (IV) compound 2 for its in vitro biocompatibility, anticancer, and antibacterial activities	44
L-valine production in Corynebacterium glutamicum based on systematic metabolic engineering: progress and prospects	43
Development, validation of a GC–MS method for the simultaneous measurement of amino acids, their PTM metabolites and AGEs in human urine, and application to the bi-ethnic ASOS study with special empha	40
Antimicrobial peptidomes of Bothrops atrox and Bothrops jararacussu snake venoms	39
Carnosine and skeletal muscle dysfunction in a rodent multiple sclerosis model	39
Functional roles of polyamines and their metabolite acrolein in eukaryotic cells	34
Branched-chain amino acids regulate intracellular protein turnover in porcine mammary epithelial cells	30
Hydroxyproline in animal metabolism, nutrition, and cell signaling	28
Association between dietary essential amino acids intake and metabolic biomarkers: influence of obesity among Chinese children and adolescents	28
Acetylcholine hydrolytic activity of fibrillated β-amyloid (1–40) peptide	26
Protein cysteine S-glycosylation: oxidative hydrolysis of protein S-glycosidic bonds in aqueous alkaline environments	25
PDZK1 improves ventricular remodeling in hypertensive rats by regulating the stability of the Mas receptor	25
Synthesis and dopamine receptor binding of dihydrexidine and SKF 38393 catecholamine-based analogues	25
Automatic radiosynthesis and preclinical evaluation of 18F-AlF-PSMA-NF as a potential PET probe for prostate cancer imaging	25
Deciphering the conformational landscape of few selected aromatic noncoded amino acids (NCAAs) for applications in rational design of peptide therapeutics	23
Disruption of kynurenine pathway reveals physiological importance of tryptophan catabolism in Henosepilachna vigintioctopunctata	23

Serum metabolomics study of narcolepsy type 1 based on ultra-performance liquid chromatography–tandem mass spectrometry	23
Paternal exposure to excessive methionine altered behavior and neurochemical activities in zebrafish offspring	23
Editorial	22
A strategy can be used to analyze intracellular interaction proteomics of cell-surface receptors	22
Synthesis and biological study of new galanthamine-peptide derivatives designed for prevention and treatment of Alzheimer’s disease	21
LEAP2 has antagonized the ghrelin receptor GHSR1a since its emergence in ancient fish	21
Untargeted metabolomics analysis of plasma metabolic characteristics in patients with acne and insulin resistance	21
Gamma-gliadin specific celiac disease antibodies recognize p31-43 and p57-68 alpha gliadin peptides in deamidation related manner as a result of cross-reaction	20
Divergent synthesis of biologically active l-threo-β-hydroxyaspartates from common trans-oxazolidine dicarboxylate	20
PYCR, a key enzyme in proline metabolism, functions in tumorigenesis	20
Molecular species of oxidized phospholipids in brain differentiate between learning- and memory impaired and unimpaired aged rats	20
Determination of amino acids in human biological fluids by high-performance liquid chromatography: critical review	19
Exploring details about structure requirements based on antioxidant tripeptide derived from β-Lactoglobulin by in silico approaches	19
Publisher’s Note: Phenolic compounds as histone deacetylase inhibitors: binding propensity and interaction insights from molecular docking and dynamics simulations	19
Global effects of RAB3GAP1 dysexpression on the proteome of mouse cortical neurons	19
Insulin stimulates β-alanine uptake in skeletal muscle cells in vitro	18
Dietary supplementation with monosodium glutamate enhances milk production by lactating sows and the growth of suckling piglets	18
An assessment of the transport mechanism and intraneuronal stability of l-carnosine	18
Oncogenic Ras expression increases cellular formate production	18
Isozymes of P5C reductase (PYCR) in human diseases: focus on cancer	17
ACP-Dnnel: anti-coronavirus peptides’ prediction based on deep neural network ensemble learning	17
Urinary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine is positively related to nitric oxide level in tissues of normotensive and hypertensive rats	17
Transcriptome analysis of l-leucine-producing Corynebacterium glutamicum under the addition of trimethylglycine	17
Greater plasma essential amino acids and lower 3-methylhistidine with higher protein intake during endurance training: a randomised control trial	17
An efficient synthesis of cis-4-hydroxyphosphonic and cis-4-hydroxyphosphinic analogs of pipecolic acid from cyclic enaminones	16
Antibiotics-induced dysbiosis in gut microbiota affects bumblebee health via regulating host amino acid metabolism	16
Apoptin NLS2 homodimerization strategy for improved antibacterial activity and bio-stability	16
Tryptophan regulates bile and nitrogen metabolism in two pig gut lactobacilli species in vitro based on metabolomics study	16
Metagenomics-based inference of microbial metabolism towards neuroactive amino acids and the response to antibiotics in piglet colon	15
Toward an understanding of tree frog (Hyla japonica) for predator deterrence	15
Targeting prostate cancer with docetaxel-loaded peptide 563-conjugated PEtOx-co-PEI30%-b-PCL polymeric micelle nanocarriers	15
Chiral secondary amino acids, their importance, and methods of analysis	15
Association between the antioxidant properties of SESN proteins and anti-cancer therapies	14
Effects of taurine on vascular tone	14
The use of BCAA to decrease delayed-onset muscle soreness after a single bout of exercise: a systematic review and meta-analysis	14
Impact of probiotic Limosilactobacillus reuteri DSM 17938 on amino acid metabolism in the healthy newborn mouse	14
Novel N-α-amino acid spacer-conjugated phthalimide–triazine derivatives: synthesis, antimicrobial and molecular docking studies	14
Homocysteine and copper ions: is their interaction responsible for cardiovascular-related damage?	13
K-aurein: A notable aurein 1.2-derived peptide that modulates Candida albicans filamentation and reduces biofilm biomass	13
Amnio acid substitution at position 298 of human glucose-6 phosphatase-α significantly impacts its stability in mammalian cells	13
Excessive dietary L-tryptophan regulated amino acids metabolism and serotonin signaling in the colon of weaning piglets with acetate-induced gut inflammation	13
Trace assay of insulin in a pharmacy drug with a paste electrode	13
Insights into the synthesis strategies of plant-derived cyclotides	12
Cystine reduces mitochondrial dysfunction in C2C12 myotubes under moderate oxidative stress induced by H2O2	12
PTPAMP: prediction tool for plant-derived antimicrobial peptides	12
Dual effects of the tryptophan-derived bacterial metabolite indole on colonic epithelial cell metabolism and physiology: comparison with its co-metabolite indoxyl sulfate	12
Research progress on the role of cationic amino acid transporter (CAT) family members in malignant tumors and immune microenvironment	12
Escherichia coli infection activates the production of IFN-α and IFN-β via the JAK1/STAT1/2 signaling pathway in lung cells	12
Effect of substituting glutamine with lysine on structural and biological properties of antimicrobial peptide Polybia-MP1	12
Purification, conformational analysis and cytotoxic activities of host-defense peptides from the Tungara frog Engystomops pustulosus (Leptodactylidae; Leiuperinae)	12

Structure, biochemistry, and gene expression patterns of the proline biosynthetic enzyme pyrroline-5-carboxylate reductase (PYCR), an emerging cancer therapy target	11
Bromelain and ficin proteolytic effects on gliadin cytotoxicity and expression of genes involved in cell-tight junctions in Caco-2 cells	11
Measurement of S-glutathionylated proteins by HPLC	11
Impact of chemical modifications on the antimicrobial and hemolytic activity of helical amphipathic peptide Lasioglossin LL-III	11
PepTraq: a toolbox for in silico data mining and fast sequence filtering	11
Acetyl group for proper protection of β-sugar-amino acids used in SPPS	11
Biochemical and in silico molecular study of caffeic acid-O-methyltransferase enzyme associated with lignin deposition in tall fescue	11
β-Aminoisobutyric acid supplementation attenuated salt-sensitive hypertension in Dahl salt-sensitive rats through prevention of insufficient fumarase	11
Serum and urinary carnosinase-1 correlate with kidney function and inflammation	10
Estimation of bioactive peptide content of milk from different species using an in silico method	10
Characterization of thermostable serine hydroxymethyltransferase for β-hydroxy amino acids synthesis	10
Proline metabolism and redox; maintaining a balance in health and disease	10
In silico and in vivo neuropharmacological evaluation of two γ-amino acid isomers derived from 2,3-disubstituted benzofurans, as ligands of GluN1–GluN2A NMDA receptor	10
Antineoplastic activity of plant-derived compounds mediated through inhibition of histone deacetylase: a review	10
PepQSAR: a comprehensive data source and information platform for peptide quantitative structure–activity relationships	10
Identification of a peptide that crosses the blood-cerebrospinal fluid barrier by phage display technology	10
Amino acids, post-translational modifications, nitric oxide, and oxidative stress in serum and urine of long COVID and ex COVID human subjects	10
Polyglutamylation: biology and analysis	10
Sulbactam improves binding property and uptake capacity of glutamate transporter-1 and decreases glutamate concentration in the CA1 region of hippocampus of global brain ischemic rats	10
Proline metabolism in cancer	10