Amino Acids

Article	Citations
BamA-targeted antimicrobial peptide design for enhanced efficacy and reduced toxicity	91
Molecular binding mechanism and novel antidiabetic and anti-hypertensive bioactive peptides from fermented camel milk with anti-inflammatory activity in raw macrophages cell lines	83
Effects of maternal branched-chain amino acid and alanine supplementation on growth and biomarkers of protein metabolism in dams fed a low-protein diet and their offspring	74
Dietary L-arginine supplementation increases the hepatic expression of AMP-activated protein kinase in rats	64
Human cell receptors: potential drug targets to combat COVID-19	60
Reply to homocysteine and copper ions: is their interaction responsible for cardiovascular‑related damage?	58
Proline oxidase silencing inhibits p53-dependent apoptosis in MCF-7 breast cancer cells	57
Cortisol enhances citrulline synthesis from proline in enterocytes of suckling piglets	56
Oral anserine supplementation does not attenuate type-2 diabetes or diabetic nephropathy in BTBR ob/ob mice	54
Screening of AS101 analog, organotellurolate (IV) compound 2 for its in vitro biocompatibility, anticancer, and antibacterial activities	44
L-valine production in Corynebacterium glutamicum based on systematic metabolic engineering: progress and prospects	43
Development, validation of a GC–MS method for the simultaneous measurement of amino acids, their PTM metabolites and AGEs in human urine, and application to the bi-ethnic ASOS study with special empha	40
Antimicrobial peptidomes of Bothrops atrox and Bothrops jararacussu snake venoms	39
Carnosine and skeletal muscle dysfunction in a rodent multiple sclerosis model	39
Functional roles of polyamines and their metabolite acrolein in eukaryotic cells	34
Branched-chain amino acids regulate intracellular protein turnover in porcine mammary epithelial cells	30
Association between dietary essential amino acids intake and metabolic biomarkers: influence of obesity among Chinese children and adolescents	28
Hydroxyproline in animal metabolism, nutrition, and cell signaling	28
Acetylcholine hydrolytic activity of fibrillated β-amyloid (1–40) peptide	26
Automatic radiosynthesis and preclinical evaluation of 18F-AlF-PSMA-NF as a potential PET probe for prostate cancer imaging	25
Protein cysteine S-glycosylation: oxidative hydrolysis of protein S-glycosidic bonds in aqueous alkaline environments	25
PDZK1 improves ventricular remodeling in hypertensive rats by regulating the stability of the Mas receptor	25
Synthesis and dopamine receptor binding of dihydrexidine and SKF 38393 catecholamine-based analogues	25
Serum metabolomics study of narcolepsy type 1 based on ultra-performance liquid chromatography–tandem mass spectrometry	23
Paternal exposure to excessive methionine altered behavior and neurochemical activities in zebrafish offspring	23

Deciphering the conformational landscape of few selected aromatic noncoded amino acids (NCAAs) for applications in rational design of peptide therapeutics	23
Disruption of kynurenine pathway reveals physiological importance of tryptophan catabolism in Henosepilachna vigintioctopunctata	23
Editorial	22
A strategy can be used to analyze intracellular interaction proteomics of cell-surface receptors	22
Synthesis and biological study of new galanthamine-peptide derivatives designed for prevention and treatment of Alzheimer’s disease	21
LEAP2 has antagonized the ghrelin receptor GHSR1a since its emergence in ancient fish	21
Untargeted metabolomics analysis of plasma metabolic characteristics in patients with acne and insulin resistance	21
Gamma-gliadin specific celiac disease antibodies recognize p31-43 and p57-68 alpha gliadin peptides in deamidation related manner as a result of cross-reaction	20
Divergent synthesis of biologically active l-threo-β-hydroxyaspartates from common trans-oxazolidine dicarboxylate	20
PYCR, a key enzyme in proline metabolism, functions in tumorigenesis	20
Molecular species of oxidized phospholipids in brain differentiate between learning- and memory impaired and unimpaired aged rats	20
Determination of amino acids in human biological fluids by high-performance liquid chromatography: critical review	19
Exploring details about structure requirements based on antioxidant tripeptide derived from β-Lactoglobulin by in silico approaches	19
Publisher’s Note: Phenolic compounds as histone deacetylase inhibitors: binding propensity and interaction insights from molecular docking and dynamics simulations	19
Global effects of RAB3GAP1 dysexpression on the proteome of mouse cortical neurons	19
Insulin stimulates β-alanine uptake in skeletal muscle cells in vitro	18
Dietary supplementation with monosodium glutamate enhances milk production by lactating sows and the growth of suckling piglets	18
An assessment of the transport mechanism and intraneuronal stability of l-carnosine	18
Oncogenic Ras expression increases cellular formate production	18
Isozymes of P5C reductase (PYCR) in human diseases: focus on cancer	17
ACP-Dnnel: anti-coronavirus peptides’ prediction based on deep neural network ensemble learning	17
Urinary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine is positively related to nitric oxide level in tissues of normotensive and hypertensive rats	17
Transcriptome analysis of l-leucine-producing Corynebacterium glutamicum under the addition of trimethylglycine	17
Greater plasma essential amino acids and lower 3-methylhistidine with higher protein intake during endurance training: a randomised control trial	17
Apoptin NLS2 homodimerization strategy for improved antibacterial activity and bio-stability	16
Tryptophan regulates bile and nitrogen metabolism in two pig gut lactobacilli species in vitro based on metabolomics study	16
An efficient synthesis of cis-4-hydroxyphosphonic and cis-4-hydroxyphosphinic analogs of pipecolic acid from cyclic enaminones	16
Antibiotics-induced dysbiosis in gut microbiota affects bumblebee health via regulating host amino acid metabolism	16
Chiral secondary amino acids, their importance, and methods of analysis	15
Metagenomics-based inference of microbial metabolism towards neuroactive amino acids and the response to antibiotics in piglet colon	15
Toward an understanding of tree frog (Hyla japonica) for predator deterrence	15
Targeting prostate cancer with docetaxel-loaded peptide 563-conjugated PEtOx-co-PEI30%-b-PCL polymeric micelle nanocarriers	15
Novel N-α-amino acid spacer-conjugated phthalimide–triazine derivatives: synthesis, antimicrobial and molecular docking studies	14
Association between the antioxidant properties of SESN proteins and anti-cancer therapies	14
Effects of taurine on vascular tone	14
The use of BCAA to decrease delayed-onset muscle soreness after a single bout of exercise: a systematic review and meta-analysis	14
Impact of probiotic Limosilactobacillus reuteri DSM 17938 on amino acid metabolism in the healthy newborn mouse	14
Homocysteine and copper ions: is their interaction responsible for cardiovascular-related damage?	13
K-aurein: A notable aurein 1.2-derived peptide that modulates Candida albicans filamentation and reduces biofilm biomass	13
Amnio acid substitution at position 298 of human glucose-6 phosphatase-α significantly impacts its stability in mammalian cells	13
Excessive dietary L-tryptophan regulated amino acids metabolism and serotonin signaling in the colon of weaning piglets with acetate-induced gut inflammation	13
Trace assay of insulin in a pharmacy drug with a paste electrode	13
Insights into the synthesis strategies of plant-derived cyclotides	12
Cystine reduces mitochondrial dysfunction in C2C12 myotubes under moderate oxidative stress induced by H2O2	12
PTPAMP: prediction tool for plant-derived antimicrobial peptides	12
Dual effects of the tryptophan-derived bacterial metabolite indole on colonic epithelial cell metabolism and physiology: comparison with its co-metabolite indoxyl sulfate	12
Research progress on the role of cationic amino acid transporter (CAT) family members in malignant tumors and immune microenvironment	12
Escherichia coli infection activates the production of IFN-α and IFN-β via the JAK1/STAT1/2 signaling pathway in lung cells	12
Effect of substituting glutamine with lysine on structural and biological properties of antimicrobial peptide Polybia-MP1	12
Purification, conformational analysis and cytotoxic activities of host-defense peptides from the Tungara frog Engystomops pustulosus (Leptodactylidae; Leiuperinae)	12

β-Aminoisobutyric acid supplementation attenuated salt-sensitive hypertension in Dahl salt-sensitive rats through prevention of insufficient fumarase	11
Structure, biochemistry, and gene expression patterns of the proline biosynthetic enzyme pyrroline-5-carboxylate reductase (PYCR), an emerging cancer therapy target	11
Bromelain and ficin proteolytic effects on gliadin cytotoxicity and expression of genes involved in cell-tight junctions in Caco-2 cells	11
Measurement of S-glutathionylated proteins by HPLC	11
Impact of chemical modifications on the antimicrobial and hemolytic activity of helical amphipathic peptide Lasioglossin LL-III	11
PepTraq: a toolbox for in silico data mining and fast sequence filtering	11
Acetyl group for proper protection of β-sugar-amino acids used in SPPS	11
Biochemical and in silico molecular study of caffeic acid-O-methyltransferase enzyme associated with lignin deposition in tall fescue	11
Sulbactam improves binding property and uptake capacity of glutamate transporter-1 and decreases glutamate concentration in the CA1 region of hippocampus of global brain ischemic rats	10
Proline metabolism in cancer	10
Identification of a peptide that crosses the blood-cerebrospinal fluid barrier by phage display technology	10
Amino acids, post-translational modifications, nitric oxide, and oxidative stress in serum and urine of long COVID and ex COVID human subjects	10
Polyglutamylation: biology and analysis	10
Characterization of thermostable serine hydroxymethyltransferase for β-hydroxy amino acids synthesis	10
Proline metabolism and redox; maintaining a balance in health and disease	10
Serum and urinary carnosinase-1 correlate with kidney function and inflammation	10
Estimation of bioactive peptide content of milk from different species using an in silico method	10
PepQSAR: a comprehensive data source and information platform for peptide quantitative structure–activity relationships	10
In silico and in vivo neuropharmacological evaluation of two γ-amino acid isomers derived from 2,3-disubstituted benzofurans, as ligands of GluN1–GluN2A NMDA receptor	10
Antineoplastic activity of plant-derived compounds mediated through inhibition of histone deacetylase: a review	10
The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression	9
The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review	9
Alkali salts of amino acids as alkaline additives for neutralization of acidic corrosion inhibitors	9
Lyophilization and homogenization of biological samples improves reproducibility and reduces standard deviation in molecular biology techniques	9
Peptide OA-VI12 restrains melanogenesis in B16 cells and C57B/6 mouse ear skin via the miR-122-5p/Mitf/Tyr axis	9
Biocidal and antibiofilm activities of arginine-based surfactants against Candida isolates	9
Possible role of SIRT1 and SIRT3 in post-translational modifications in human breast milk during the neonatal period	9
Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyelination in mice—a behavioral and immunohistochemical study	9
Common pathogenic bacteria-induced reprogramming of the host proteinogenic amino acids metabolism	9
The serum amino acid profile in COVID-19	9
Chromogranin A-derived peptides pancreastatin and catestatin: emerging therapeutic target for diabetes	9
Correction to: The novel inhibitors of serine proteases	9
Amino acid analysis as a method of discovering biomarkers for diagnosis of diabetes and its complications	9
Ferrihydrite synthesis in the presence of amino acids and artificial seawater	9
Characterization of a polyclonal antibody that is highly selective for the d-isoAsp-25 variant of mammalian histone H2B	8
Free threonine in human breast milk is related to infant intestinal microbiota composition	8
Oxidation of amino acids, glucose, and fatty acids as metabolic fuels in enterocytes of developing pigs	8
Taurine protects R28 cells from hypoxia/re-oxygenation-induced damage via regulation of mitochondrial energy metabolism	8
Age-associated polyamines in peripheral blood cells and plasma in 20 to 70 years of age subjects	8
Taurine protects dopaminergic neurons in paraquat-induced Parkinson’s disease mouse model through PI3K/Akt signaling pathways	8
Effects and underlying mechanisms of L-arginine on spontaneous muscle contraction of rat colon	8
CSC01 shows promise as a potential inhibitor of the oncogenic G13D mutant of KRAS: an in silico approach	8
Metabolomic profiling of amino acids study reveals a distinct diagnostic model for diabetic kidney disease	8
Cross-sectional relationships between general and central adiposity and plasma amino acids in Chinese adults	8
Optimizing the synthesis of dimeric peptides: influence of the reaction medium and effects that modulate kinetics and reaction yield	8
Serum branched amino acids and the risk of all-cause mortality: a meta-analysis and systematic review	8
Methylarginine efflux in nutrient-deprived yeast mitigates disruption of nitric oxide synthesis	8
The biological interactions between kynurenine and AhR in melanocytes: in vitro studies	8
Dietary amino acids and intestinal microbiota	8
Mining proteomics data to extract post-translational modifications associated with gastric cancer	8
Amino acids-targeted metabolomics reveals novel diagnostic biomarkers for ulcerative colitis and Crohn’s disease	8
Evaluation of oilseed proteins as precursors of antimicrobial peptides using bioinformatics method	8
Mouse skin peptidomic analysis of the hemorrhage induced by a snake venom metalloprotease	7
ImitateDB: A database for domain and motif mimicry incorporating host and pathogen protein interactions	7
Methylmalonic acid induces inflammatory response and redox homeostasis disruption in C6 astroglial cells: potential glioprotective roles of melatonin and resveratrol	7
Identification of bacterial lipo-amino acids: origin of regenerated fatty acid carboxylate from dissociation of lipo-glutamate anion	7
Photochemical synthesis of pink silver and its use for monitoring peptide nitration via surface enhanced Raman spectroscopy (SERS)	7
PyProtif: a PyMol plugin to retrieve and visualize protein motifs for structural studies	7
The effects of incorporation of the counterparts and mimics of l-lysine on the antimicrobial activity, hemolytic activity, cytotoxicity and tryptic stability of antimicrobial peptide polybia-MPII	7
Cul5 mediates taurine-stimulated mTOR mRNA expression and proliferation of mouse mammary epithelial cells	7
PepAnalyzer: predicting peptide properties using its sequence	7
Structural characterisation and pH-dependent preference of pyrrole cross-link isoforms from reactions of oxoenal with cysteine and lysine side chains as model systems	7
The potential roles of amino acids and their major derivatives in the management of multiple sclerosis	7
In silico identification of novel ACE and DPP-IV inhibitory peptides derived from buffalo milk proteins and evaluation of their inhibitory mechanisms	7
A mutation in the S6 segment of the KvAP channel changes the secondary structure and alters ion channel activity in a lipid bilayer membrane	7
Effects of sulphur amino acids on the size and structure of microbial communities of aerobic granular sludge bioreactors	7
Influence of the Dabcyl group on the cellular uptake of cationic peptides: short oligoarginines as efficient cell-penetrating peptides	7
Sodium pyruvate improves the plasma amino acid profile in rats with l-arginine-induced acute pancreatitis	6
Chiral resolution of plasma amino acids reveals enantiomer-selective associations with organ functions	6
Racemization-free synthesis of Nα-2-thiophenoyl-phenylalanine-2-morpholinoanilide enantiomers and their antimycobacterial activity	6
Investigating molecular interactions between human transferrin and resveratrol through a unified experimental and computational approach: Role of natural compounds in Alzheimer’s disease therapeutics	6
Far-UV circular dichroism signatures indicate fluorophore labeling induced conformational changes of penetratin	6
Impact of essential amino acid intake, resistance exercise, and aging on the concentration of Achilles peritendinous amino acids and procollagen Iα1 in humans	6
Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity	6
Synthesis and screening for anticancer activity of two novel telluro-amino acids: 1,3-Tellurazolidine-4-carboxylic acid and tellurohomocystine	6
Effect of AMPK activation and glucose availability on myotube LAT1 expression and BCAA utilization	6
A mix of functional amino acids and grape polyphenols promotes the growth of piglets, modulates the gut microbiota in vivo and regulates epithelial homeostasis in intestinal organoids	6
Antimicrobial peptide-loaded decellularized placental sponge as an excellent antibacterial skin substitute against XDR clinical isolates	6
Allyl isothiocyanate inhibits invasion and angiogenesis in breast cancer via EGFR-mediated JAK-1/STAT-3 signaling pathway	6
Hypertension alters the function and expression profile of the peptide cotransporters PEPT1 and PEPT2 in the rodent renal proximal tubule	6

Postprandial amino acid availability after intake of intact or hydrolyzed meat protein in a mixed meal in healthy elderly subjects: a randomized, single blind crossover trial	6
The effect of insulin resistance on extracellular BCAA accumulation and SLC25A44 expression in a myotube model of skeletal muscle insulin resistance	6
Dietary leucine requirement of fingerling Channa punctatus (Bloch) based on growth, feed conversion and leucine retention efficiency, hematological parameters, antioxidant and intestinal enzyme activi	6
L-leucine stimulation of glucose uptake and utilization involves modulation of glucose – lipid metabolic switch and improved bioenergetic homeostasis in isolated rat psoas muscle ex vivo	6
ATGPred-FL: sequence-based prediction of autophagy proteins with feature representation learning	6
Effect of lipopeptide extracted from Bacillus licheniformis on the expression of bap and luxI genes in multi-drug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa	6
Current status of PTMs structural databases: applications, limitations and prospects	6
Correction to: The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression	6
Embryonic exposure to acetyl-L-carnitine protects against valproic acid-induced cardiac malformation in zebrafish model	5
Meta-proteomic analysis of the Shandrin mammoth by EVA technology and high-resolution mass spectrometry: what is its gut microbiota telling us?	5
A two-step ensemble learning for predicting protein hot spot residues from whole protein sequence	5
Decreased fasting serum glucogenic amino acids with a higher compared to normal protein diet during energy restriction in women: a randomized controlled trial	5
Authentication of three main commercial Pheretima based on amino acids analysis	5
Characterization of d-amino acids in colostral, transitional, and mature preterm human milk	5
Amino acid metabolism as a therapeutic target in cancer: a review	5
Meta-proteomic analysis of two mammoth’s trunks by EVA technology and high-resolution mass spectrometry for an indirect picture of their habitat and the characterization of the collagen type I, alpha-	5
Serum albumin acted as an effective carrier to improve the stability of bioactive flavonoid	5
Influence of amino acid and N-terminal protection residue structures on peptide p-nitroanilide adsorption on polystyrene-based support	5
Dietary l-arginine supplementation of tilapia (Oreochromis niloticus) alters the microbial population and activates intestinal fatty acid oxidation	5
Involvement of the fecal amino acid profile in a clinical and anthropometric study of Mexican patients with insulin resistance and type 2 diabetes mellitus	5
Predicted novel hypertrehalosaemic peptides of cockroaches are verified by mass spectrometry	5
Development of peptide-based biosensors for detecting cross-linking and deamidation activities of transglutaminases	5
Interaction of exercise training with taurine attenuates infarct size and cardiac dysfunction via Akt–Foxo3a–Caspase-8 signaling pathway	5
Carnosine alleviates kidney tubular epithelial injury by targeting NRF2 mediated ferroptosis in diabetic nephropathy	5
Alarin alleviated cardiac fibrosis via attenuating oxidative stress in heart failure rats	5
l-Arginine is a feasible supplement to heal chronic anal fissure via reducing internal anal sphincter pressure: a randomized clinical trial study	5
Cross species review of the physiological role of d-serine in translationally relevant behaviors	5
Semi-rational design of L-amino acid deaminase for production of pyruvate and d-alanine by Escherichia coli whole-cell biocatalyst	5
Characterization of a novel + 70 Da modification in rhGM-CSF expressed in E. coli using chemical assays in combination with mass spectrometry	5
HPLC method with post-column derivatization for the analysis of endogenous histidine in human saliva validated using the total-error concept	5
Intracerebroventricular injection taurine changes free amino acid concentrations in the brain and plasma in chicks	5
Dietary L-arginine supplementation during days 14–25 of gestation enhances aquaporin expression in the placentae and endometria of gestating gilts	4
Crystalline structures of l-cysteine and l-cystine: a combined theoretical and experimental characterization	4
An in vitro assay of the effect of lysine oxidation end-product, α-aminoadipic acid, on the redox status and gene expression in probiotic Lactobacillus reuteri PL503	4
Post-translational formation of hypusine in eIF5A: implications in human neurodevelopment	4
Fibroblast growth factor 9 attenuates sepsis-induced fulminant hepatitis in mice	4
Biochemistry of plants N–heterocyclic non-protein amino acids	4
Comparison of homocitrulline and carbamylated albumin as biomarkers of carbamylation reactions in hemodialyzed patients	4
Emerging effects of tryptophan pathway metabolites and intestinal microbiota on metabolism and intestinal function	4
Electrostatically induced pKa shifts in oligopeptides: the upshot of neighboring side chains	4
Sex-related differences in plasma amino acids of patients with ST-elevation myocardial infarction and glycine as risk marker of acute heart failure with preserved ejection fraction	4
The renoprotective effects of taurine against diabetic nephropathy via the p38 MAPK and TGF-β/Smad2/3 signaling pathways	4
Specific and sensitive GC–MS analysis of hypusine, Nε-(4-amino-2-hydroxybutyl)lysine, a biomarker of hypusinated eukaryotic initiation factor eIF5A, and its application to the bi-ethnic ASOS study	4
Detection of impurities in dietary supplements containing l-tryptophan	4
Apoptosis-mediated anticancer activity in prostate cancer cells of a chestnut honey (Castanea sativa L.) quinoline–pyrrolidine gamma-lactam alkaloid	4
Simultaneous determination of l-tryptophan impurities in meat products	4
Amino acid-stimulated insulin secretion: a path forward in type 2 diabetes	4
Effects of sex and estrous cycle on the brain and plasma arginine metabolic profile in rats	4
Stereoselective synthesis of S-norvaline and related amino acids through a common intermediate	4
Interorgan amino acid interchange in propionic acidemia: the missing key to understanding its physiopathology	4
Early vascular ageing phenotypes and urinary targeted metabolomics in children and young adults: the ExAMIN Youth SA and African-PREDICT studies	4
Membrane interactions of Ocellatins. Where do antimicrobial gaps stem from?	4
Effects of l-ascorbic acid (C6H8O6: Vit-C) on collagen amino acids: DFT study	4
Promotion of rs3746804 (p. L267P) polymorphism to intracellular SLC52A3a trafficking and riboflavin transportation in esophageal cancer cells	4
Plasma free amino acid profiles are associated with serum high molecular weight adiponectin levels in Japanese medical check-up population without type 2 diabetes mellitus	4
Serum amino acid profiles in patients with myasthenia gravis	4
The role of SHMT2 in modulating lipid metabolism in hepatocytes via glycine-mediated mTOR activation	4
Molecular insight into the affinity, specificity and cross-reactivity of systematic hepatocellular carcinoma RALT interaction profile with human receptor tyrosine kinases	4
A novel antibacterial approach of Cecropin-B peptide loaded on chitosan nanoparticles against MDR Klebsiella pneumoniae isolates	4
Using the dual isotope method to assess cecal amino acid absorption of goat whey protein in rats, a pilot study	4
Furanonyl amino acid derivatives as hemostatic drugs: design, synthesis and hemostasis performance	4
GABAergic circuits of the basolateral amygdala and generation of anxiety after traumatic brain injury	4
Multiple sclerosis and myelin basic protein: insights into protein disorder and disease	4
Free amino acid contents of selected Ethiopian plant and fungi species: a search for alternative natural free amino acid sources for cosmeceutical applications	4
Potential of milk-derived bioactive peptides as antidiabetic, antihypertensive, and xanthine oxidase inhibitors: a comprehensive bibliometric analysis and updated review	4
d-Amino acid recognition of tripeptides studied by ultraviolet photodissociation spectroscopy of hydrogen-bonded clusters	4