OOIR: Observatory of International Research

Papers

(The median citation count of Amino Acids is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Effects of maternal branched-chain amino acid and alanine supplementation on growth and biomarkers of protein metabolism in dams fed a low-protein diet and their offspring	107
BamA-targeted antimicrobial peptide design for enhanced efficacy and reduced toxicity	106
Branched-chain amino acids regulate intracellular protein turnover in porcine mammary epithelial cells	70
Dietary L-arginine supplementation increases the hepatic expression of AMP-activated protein kinase in rats	51
Molecular binding mechanism and novel antidiabetic and anti-hypertensive bioactive peptides from fermented camel milk with anti-inflammatory activity in raw macrophages cell lines	47
A strategy can be used to analyze intracellular interaction proteomics of cell-surface receptors	32
Screening of AS101 analog, organotellurolate (IV) compound 2 for its in vitro biocompatibility, anticancer, and antibacterial activities	32
Deciphering the conformational landscape of few selected aromatic noncoded amino acids (NCAAs) for applications in rational design of peptide therapeutics	31
Synthesis and dopamine receptor binding of dihydrexidine and SKF 38393 catecholamine-based analogues	31
PDZK1 improves ventricular remodeling in hypertensive rats by regulating the stability of the Mas receptor	26
Serum metabolomics study of narcolepsy type 1 based on ultra-performance liquid chromatography–tandem mass spectrometry	25
Acetylcholine hydrolytic activity of fibrillated β-amyloid (1–40) peptide	25
Protein cysteine S-glycosylation: oxidative hydrolysis of protein S-glycosidic bonds in aqueous alkaline environments	25
Exploring details about structure requirements based on antioxidant tripeptide derived from β-Lactoglobulin by in silico approaches	23
Editorial	21
Synthesis and biological study of new galanthamine-peptide derivatives designed for prevention and treatment of Alzheimer’s disease	20
Divergent synthesis of biologically active l-threo-β-hydroxyaspartates from common trans-oxazolidine dicarboxylate	20
Publisher’s Note: Phenolic compounds as histone deacetylase inhibitors: binding propensity and interaction insights from molecular docking and dynamics simulations	19
Untargeted metabolomics analysis of plasma metabolic characteristics in patients with acne and insulin resistance	19
Molecular species of oxidized phospholipids in brain differentiate between learning- and memory impaired and unimpaired aged rats	19
Dietary supplementation with monosodium glutamate enhances milk production by lactating sows and the growth of suckling piglets	17
Urinary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine is positively related to nitric oxide level in tissues of normotensive and hypertensive rats	17
Apoptin NLS2 homodimerization strategy for improved antibacterial activity and bio-stability	17
Greater plasma essential amino acids and lower 3-methylhistidine with higher protein intake during endurance training: a randomised control trial	17
ACP-Dnnel: anti-coronavirus peptides’ prediction based on deep neural network ensemble learning	17

Antibiotics-induced dysbiosis in gut microbiota affects bumblebee health via regulating host amino acid metabolism	16
Transcriptome analysis of l-leucine-producing Corynebacterium glutamicum under the addition of trimethylglycine	16
Effects of taurine on vascular tone	15
Novel N-α-amino acid spacer-conjugated phthalimide–triazine derivatives: synthesis, antimicrobial and molecular docking studies	15
An efficient synthesis of cis-4-hydroxyphosphonic and cis-4-hydroxyphosphinic analogs of pipecolic acid from cyclic enaminones	15
Tryptophan regulates bile and nitrogen metabolism in two pig gut lactobacilli species in vitro based on metabolomics study	15
Impact of probiotic Limosilactobacillus reuteri DSM 17938 on amino acid metabolism in the healthy newborn mouse	14
Metagenomics-based inference of microbial metabolism towards neuroactive amino acids and the response to antibiotics in piglet colon	14
Association between the antioxidant properties of SESN proteins and anti-cancer therapies	14
Targeting prostate cancer with docetaxel-loaded peptide 563-conjugated PEtOx-co-PEI30%-b-PCL polymeric micelle nanocarriers	14
Insights into the synthesis strategies of plant-derived cyclotides	13
Purification, conformational analysis and cytotoxic activities of host-defense peptides from the Tungara frog Engystomops pustulosus (Leptodactylidae; Leiuperinae)	13
Trace assay of insulin in a pharmacy drug with a paste electrode	13
β-Aminoisobutyric acid supplementation attenuated salt-sensitive hypertension in Dahl salt-sensitive rats through prevention of insufficient fumarase	13
Cystine reduces mitochondrial dysfunction in C2C12 myotubes under moderate oxidative stress induced by H2O2	13
Chiral secondary amino acids, their importance, and methods of analysis	13
Dual effects of the tryptophan-derived bacterial metabolite indole on colonic epithelial cell metabolism and physiology: comparison with its co-metabolite indoxyl sulfate	13
Amnio acid substitution at position 298 of human glucose-6 phosphatase-α significantly impacts its stability in mammalian cells	13
Excessive dietary L-tryptophan regulated amino acids metabolism and serotonin signaling in the colon of weaning piglets with acetate-induced gut inflammation	13
Serum and urinary carnosinase-1 correlate with kidney function and inflammation	12
Antineoplastic activity of plant-derived compounds mediated through inhibition of histone deacetylase: a review	12
Research progress on the role of cationic amino acid transporter (CAT) family members in malignant tumors and immune microenvironment	12
K-aurein: A notable aurein 1.2-derived peptide that modulates Candida albicans filamentation and reduces biofilm biomass	12
Acetyl group for proper protection of β-sugar-amino acids used in SPPS	12
Biochemical and in silico molecular study of caffeic acid-O-methyltransferase enzyme associated with lignin deposition in tall fescue	12
PTPAMP: prediction tool for plant-derived antimicrobial peptides	12
PepTraq: a toolbox for in silico data mining and fast sequence filtering	12
Bromelain and ficin proteolytic effects on gliadin cytotoxicity and expression of genes involved in cell-tight junctions in Caco-2 cells	12
Effect of substituting glutamine with lysine on structural and biological properties of antimicrobial peptide Polybia-MP1	12
Chromogranin A-derived peptides pancreastatin and catestatin: emerging therapeutic target for diabetes	11
In silico and in vivo neuropharmacological evaluation of two γ-amino acid isomers derived from 2,3-disubstituted benzofurans, as ligands of GluN1–GluN2A NMDA receptor	11
Polyglutamylation: biology and analysis	11
Estimation of bioactive peptide content of milk from different species using an in silico method	11
Amino acids, post-translational modifications, nitric oxide, and oxidative stress in serum and urine of long COVID and ex COVID human subjects	11
Impact of chemical modifications on the antimicrobial and hemolytic activity of helical amphipathic peptide Lasioglossin LL-III	11
Characterization of thermostable serine hydroxymethyltransferase for β-hydroxy amino acids synthesis	10
Peptide OA-VI12 restrains melanogenesis in B16 cells and C57B/6 mouse ear skin via the miR-122-5p/Mitf/Tyr axis	10
Possible role of SIRT1 and SIRT3 in post-translational modifications in human breast milk during the neonatal period	10
PepQSAR: a comprehensive data source and information platform for peptide quantitative structure–activity relationships	10
Biocidal and antibiofilm activities of arginine-based surfactants against Candida isolates	10
Common pathogenic bacteria-induced reprogramming of the host proteinogenic amino acids metabolism	10
The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression	10
Correction to: The novel inhibitors of serine proteases	10
Amino acid analysis as a method of discovering biomarkers for diagnosis of diabetes and its complications	10
Ferrihydrite synthesis in the presence of amino acids and artificial seawater	9
Methylarginine efflux in nutrient-deprived yeast mitigates disruption of nitric oxide synthesis	9
Amino acids-targeted metabolomics reveals novel diagnostic biomarkers for ulcerative colitis and Crohn’s disease	9
Age-associated polyamines in peripheral blood cells and plasma in 20 to 70 years of age subjects	9
Alkali salts of amino acids as alkaline additives for neutralization of acidic corrosion inhibitors	9
Effects and underlying mechanisms of L-arginine on spontaneous muscle contraction of rat colon	9

The biological interactions between kynurenine and AhR in melanocytes: in vitro studies	9
Optimizing the synthesis of dimeric peptides: influence of the reaction medium and effects that modulate kinetics and reaction yield	9
Cross-sectional relationships between general and central adiposity and plasma amino acids in Chinese adults	9
Characterization of a polyclonal antibody that is highly selective for the d-isoAsp-25 variant of mammalian histone H2B	9
CSC01 shows promise as a potential inhibitor of the oncogenic G13D mutant of KRAS: an in silico approach	9
Taurine protects R28 cells from hypoxia/re-oxygenation-induced damage via regulation of mitochondrial energy metabolism	9
Mining proteomics data to extract post-translational modifications associated with gastric cancer	9
Oxidation of amino acids, glucose, and fatty acids as metabolic fuels in enterocytes of developing pigs	9
Evaluation of oilseed proteins as precursors of antimicrobial peptides using bioinformatics method	8
The effects of incorporation of the counterparts and mimics of l-lysine on the antimicrobial activity, hemolytic activity, cytotoxicity and tryptic stability of antimicrobial peptide polybia-MPII	8
Dietary amino acids and intestinal microbiota	8
Mouse skin peptidomic analysis of the hemorrhage induced by a snake venom metalloprotease	8
Photochemical synthesis of pink silver and its use for monitoring peptide nitration via surface enhanced Raman spectroscopy (SERS)	8
Taurine protects dopaminergic neurons in paraquat-induced Parkinson’s disease mouse model through PI3K/Akt signaling pathways	8
Metabolomic profiling of amino acids study reveals a distinct diagnostic model for diabetic kidney disease	8
Serum branched amino acids and the risk of all-cause mortality: a meta-analysis and systematic review	8
Sodium pyruvate improves the plasma amino acid profile in rats with l-arginine-induced acute pancreatitis	7
A mutation in the S6 segment of the KvAP channel changes the secondary structure and alters ion channel activity in a lipid bilayer membrane	7
Structural characterisation and pH-dependent preference of pyrrole cross-link isoforms from reactions of oxoenal with cysteine and lysine side chains as model systems	7
PyProtif: a PyMol plugin to retrieve and visualize protein motifs for structural studies	7
Identification of bacterial lipo-amino acids: origin of regenerated fatty acid carboxylate from dissociation of lipo-glutamate anion	7
ATGPred-FL: sequence-based prediction of autophagy proteins with feature representation learning	7
Effects of sulphur amino acids on the size and structure of microbial communities of aerobic granular sludge bioreactors	7
ImitateDB: A database for domain and motif mimicry incorporating host and pathogen protein interactions	7
PepAnalyzer: predicting peptide properties using its sequence	7
Methylmalonic acid induces inflammatory response and redox homeostasis disruption in C6 astroglial cells: potential glioprotective roles of melatonin and resveratrol	7
In silico identification of novel ACE and DPP-IV inhibitory peptides derived from buffalo milk proteins and evaluation of their inhibitory mechanisms	7
The potential roles of amino acids and their major derivatives in the management of multiple sclerosis	7
Cul5 mediates taurine-stimulated mTOR mRNA expression and proliferation of mouse mammary epithelial cells	7
Investigating molecular interactions between human transferrin and resveratrol through a unified experimental and computational approach: Role of natural compounds in Alzheimer’s disease therapeutics	6
Chiral resolution of plasma amino acids reveals enantiomer-selective associations with organ functions	6
Antimicrobial peptide-loaded decellularized placental sponge as an excellent antibacterial skin substitute against XDR clinical isolates	6
Current status of PTMs structural databases: applications, limitations and prospects	6
Correction to: The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression	6
Synthesis and screening for anticancer activity of two novel telluro-amino acids: 1,3-Tellurazolidine-4-carboxylic acid and tellurohomocystine	6
Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity	6
Effect of AMPK activation and glucose availability on myotube LAT1 expression and BCAA utilization	6
Allyl isothiocyanate inhibits invasion and angiogenesis in breast cancer via EGFR-mediated JAK-1/STAT-3 signaling pathway	6
Hypertension alters the function and expression profile of the peptide cotransporters PEPT1 and PEPT2 in the rodent renal proximal tubule	6
Impact of essential amino acid intake, resistance exercise, and aging on the concentration of Achilles peritendinous amino acids and procollagen Iα1 in humans	6
Effect of lipopeptide extracted from Bacillus licheniformis on the expression of bap and luxI genes in multi-drug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa	6
Dietary leucine requirement of fingerling Channa punctatus (Bloch) based on growth, feed conversion and leucine retention efficiency, hematological parameters, antioxidant and intestinal enzyme activi	6
The effect of insulin resistance on extracellular BCAA accumulation and SLC25A44 expression in a myotube model of skeletal muscle insulin resistance	6
Far-UV circular dichroism signatures indicate fluorophore labeling induced conformational changes of penetratin	6
Interaction of exercise training with taurine attenuates infarct size and cardiac dysfunction via Akt–Foxo3a–Caspase-8 signaling pathway	6
Detection of impurities in dietary supplements containing l-tryptophan	5
Cross species review of the physiological role of d-serine in translationally relevant behaviors	5
The role of SHMT2 in modulating lipid metabolism in hepatocytes via glycine-mediated mTOR activation	5
Involvement of the fecal amino acid profile in a clinical and anthropometric study of Mexican patients with insulin resistance and type 2 diabetes mellitus	5
Predicted novel hypertrehalosaemic peptides of cockroaches are verified by mass spectrometry	5
Embryonic exposure to acetyl-L-carnitine protects against valproic acid-induced cardiac malformation in zebrafish model	5
Influence of amino acid and N-terminal protection residue structures on peptide p-nitroanilide adsorption on polystyrene-based support	5
Effects of l-ascorbic acid (C6H8O6: Vit-C) on collagen amino acids: DFT study	5
Serum amino acid profiles in patients with myasthenia gravis	5
Simultaneous determination of l-tryptophan impurities in meat products	5
Carnosine alleviates kidney tubular epithelial injury by targeting NRF2 mediated ferroptosis in diabetic nephropathy	5
Intracerebroventricular injection taurine changes free amino acid concentrations in the brain and plasma in chicks	5
l-Arginine is a feasible supplement to heal chronic anal fissure via reducing internal anal sphincter pressure: a randomized clinical trial study	5
Characterization of d-amino acids in colostral, transitional, and mature preterm human milk	5
Multiple sclerosis and myelin basic protein: insights into protein disorder and disease	5
Crystalline structures of l-cysteine and l-cystine: a combined theoretical and experimental characterization	5
A novel antibacterial approach of Cecropin-B peptide loaded on chitosan nanoparticles against MDR Klebsiella pneumoniae isolates	5
Meta-proteomic analysis of two mammoth’s trunks by EVA technology and high-resolution mass spectrometry for an indirect picture of their habitat and the characterization of the collagen type I, alpha-	5
HPLC method with post-column derivatization for the analysis of endogenous histidine in human saliva validated using the total-error concept	5
A two-step ensemble learning for predicting protein hot spot residues from whole protein sequence	5
Serum albumin acted as an effective carrier to improve the stability of bioactive flavonoid	5
Development of peptide-based biosensors for detecting cross-linking and deamidation activities of transglutaminases	5