Current Medicinal Chemistry

Article	Citations
Corrigendum to: Update of the Preclinical Situation of Anticancer Platinum Complexes: Novel Design Strategies and Innovative Analytical Approaches	111
Challenges of Natural Anticancer and Anti-inflammatory Agents	105
Identification of Critical Genes Related to Breast Cancer with Brain Metastasis Through Bioinformatics Analysis	86
Intermittent Fasting and Fasting-mimicking Diet: Promising Strategies in Cancer Management	64
Multimodality Cardiac Imaging Biomarkers and Atrial Fibrillation Substrate: Are they Worthwhile?	60
Drug-Resistant Infections: A Global Challenge for the Future	58
Paneth Cells: Recent Updates on Elucidating Therapeutic Implications in Gastroenterological Disease Management	58
Commentary on the Role of Medicinal Cannabis in Healthy Aging and Neuroprotection	57
Chalcogenium-AZT Derivatives: A Plausible Strategy To Tackle The RT-Inhibitors-Related Oxidative Stress While Maintaining Their Anti- HIV Properties	57
Research Prospects for the Mitochondria in Glaucoma: A Bibliometric Analysis	54
MEF2C is a Potential Prognostic Biomarker and is Correlated with Immune Infiltrates in Lung Adenocarcinoma	53
Expression of TCEAL2 is a Novel Prognostic Biomarker and Potential Therapeutic Target in Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma	51
Potential Therapeutic Targets for the Management of Diabetes Mellitus Type 2	50
Development in the Inhibition of Dengue Proteases as Drug Targets	48
Statins, Allies against Antibiotic Resistance?	48
Revisiting the Role of B-RAF Kinase as a Therapeutic Target in Melanoma	46
Determination of the 95% Effective Dose of Remifentanil for Moderate Sedation During Gastroscopy in Obese Patients	42
Role of Ferroptosis in ALD: Focusing on Hepcidin and Besides Hepcidin	41
TRIP13 Activates Glycolysis to Promote Cell Stemness and Strengthen Doxorubicin Resistance of Colorectal Cancer Cells	41
Naturally Occurring Xanthones; Biological Activities, Chemical Profiles and In Silico Drug Discovery	40
Analysis and Validation of Tyrosine Metabolism-related Prognostic Features for Liver Hepatocellular Carcinoma Therapy	39
Autophagy-related ncRNAs: Regulatory Roles and Potential Therapeutic Effects in Digestive System Neoplasms	39
New Insights into the Long Non-coding RNAs Dependent Modulation of Heart Failure and Cardiac Hypertrophy: From Molecular Function to Diagnosis and Treatment	38
Recent Advances in Lung Cancer Therapy Based on Nanomaterials: A Review	35
Exploring the Anticancer Potential of Astragalin in Triple Negative Breast Cancer Cells by Attenuating Glycolytic Pathway through AMPK/mTOR	35

Intimal Macrovascular Pericytes: Their Role in Vascular Biology and Atherogenesis	34
SGLT-2 Inhibitors: The Next-generation Treatment for Type 2 Diabetes Mellitus	34
Prediction of Prognosis and Immunotherapy Response of Gastric Cancer Based on Glutamine Metabolism-related Genes	33
Design, Synthesis, and Pharmacological Characterization of Substituted Quinoxalines as NOP Receptor Ligands	33
Neuroinflammatory Human Brain Organoids Enable Comprehensive Drug Screening Studies: Fingolimod and its Analogues in Focus	33
Potential for Novel Therapeutic Uses of Alpha Lipoic Acid	33
Long Non-coding RNA DLGAP1-AS1 and DLGAP1-AS2: Two Novel Oncogenes in Multiple Cancers	32
Exploring the Possible Role of Gut Microbiota with Ischemic Stroke Subtypes: A Mendelian Randomization Study with Insights into Immune Cell Mediators	32
Resveratrol Inhibits Hepatocellular Carcinoma Progression through Regulating Exosome Secretion	31
Detection of Prostate Cancer Biomarker PCA3 by Using Aptasensors	31
ANGPTL4-the Link Binding Lipid Metabolism and Inflammation	30
The Effects of Curcumin on Brain-Derived Neurotrophic Factor Expression in Neurodegenerative Disorders	30
An Updated Review Deciphering Apigenin Nanostructures as Promising Therapeutic Efficiency in Human Carcinomas	30
Exosomal miR-451 Inhibits Ferroptosis by Targeting the PHD3/p53 Signaling Axis to Protect against Ischemic Stroke	29
Long Non-coding RNA SNHG16 Facilitates Esophageal Cancer Cell Proliferation and Self-renewal through the microRNA-802/PTCH1 Axis	29
Ganaxolone: First FDA-approved Medicine for the Treatment of Seizures Associated with Cyclin-dependent Kinase-like 5 Deficiency Disorder	29
Mitochondrial DNA Mutations in Colorectal Cancer Stem Cells: Implications for Tumor Dynamics and Therapeutic Strategies	29
Developing Generalizable Scoring Functions for Molecular Docking: Challenges and Perspectives	29
Role of Flavonoids in Management of Various Biological Targets in Alzheimer’s Disease: Evidence from Preclinical to Clinical Studies	29
Integrated Exploration of Pyranocoumarin Derivatives as Synergistic Inhibitors of Dual-target for Mpro and PLpro Proteins of SARS-CoV- 2 through Molecular Docking, ADMET Analysis, and Molecular Dynami	29
Integrating Transcriptomic Data and Mendelian Randomization Analyses Reveals Potentially Novel Sepsis-related Targets	28
Predicting Clinical Outcomes and Immunotherapy Responses in Lung Adenocarcinoma Based on Nicotine Response Characteristics	28
Clinical Application and Synthesis Methods of Deuterated Drugs	27
Activating Protein-1 (AP-1): A Promising Target for the Treatment of Fibrotic Diseases	27
Serine Protease 27, a Prognostic Biomarker in Pan-cancer and Associated with the Aggressive Progression of Breast Cancer	27
Construction and Biological Evaluation of Different Nanoshell Thickness Ni@SiO2 Nanotubes as Good Protein Separation Carriers for Bovine Hemoglobin	27
Augmented Anti-leukemic Efficacy of Selenium-Fermented Ferulic Acid Derived from Macrotyloma uniflorum: Insights into in vitro and in vivo Models	26
Futibatinib: A Potent and Irreversible Inhibitor of Fibroblast Growth Factor Receptors for Treatment of the Bile Duct Cancer	26
Meet the Editorial Board Member	26
A Bi-directional Mendelian Randomization Study of Idiopathic Pulmonary Fibrosis and Six Diabetes-related Traits	26
Synthesis Techniques and Biomedical Applications of Cyclodextrin Metal-organic Frameworks	26
Recent Advances on PKM2 Inhibitors and Activators in Cancer Applications	26
LncRNA HYMAI Promotes Endothelial Cell Autophagy via miR-19a-3p/ ATG14 to Attenuate the Progression of Coronary Atherosclerotic Disease	26
Meet the Editorial Board Member	26
Synthesis of β-Amino Carbonyl 6-(Aminomethyl)- and 6-(Hydroxymethyl)pyrazolopyrimidines for DPP-4 Inhibition Study	26
To Elucidate the Effective Role of Small Molecule Regulated lncRNAs in the Tumour Microenvironment in Immunotherapy	25
Molecular Subtypes and Prognostic Models for Predicting Prognosis of Lung Adenocarcinoma based on MiRNA-related Genes	25
New Molecules of Importance in the Prevention and Treatment of Acne: A Systematic Patent Review (2016-2020)	25
Quantum Consciousness: A Molecular Perspective Involving Glycoprotein-Tunnelling Hypothesis (GPTH)	25
Novel Natural Inhibitors for Glioblastoma by Targeting Epidermal Growth Factor Receptor and Phosphoinositide 3-kinase	25
Biomarkers and Emerging Drug Targets in Neuropsychiatry (Part II)	25
The Effect of Gallic Acid on the Alleviation of the Chemotherapyinduced Myelosuppression	25
The Therapeutic Potential of Melatonin in Alzheimer's Disease: A Comprehensive Review	25
Construction and Evaluation of a Prognostic Model Based on Efferocytosis-related Genes for Idiopathic Pulmonary Fibrosis	24
Pre-Stage Oral Cancer Biomarker Analysis in Non-invasive Salivary Samples: A Way to Go	24
Perspectives toward the Development of Advanced Materials Based on Bacterial Polysaccharides	24
Machine Learning-based Macrophage Signature for Predicting Prognosis and Immunotherapy Benefits in Cholangiocarcinoma	24
The Role and Molecular Mechanism of Icaritin in the Treatment of Alzheimer's Disease	23
Characterization of Tumor Microenvironment and Prognosis of Regulatory T cells-Related Subtypes	23
N-Methyl-D-Aspartate (NMDA) Receptor Antagonists and their Pharmacological Implication: A Medicinal Chemistry-oriented Perspective Outline	23

Synthesis and Antiproliferative Activity against Melanoma Cells of New Heterocyclic Hybrids Based on Pyridine and Pyrimidine Scaffolds	22
Hybrid Nanoparticles for Cancer Theranostics: A Critical Review on Design, Synthesis, and Multifunctional Capabilities	22
Microwave Induced Green Synthesis: Sustainable Technology for Efficient Development of Bioactive Pyrimidine Scaffolds	22
Bacterial Polyhydroxyalkanoates-based Therapeutics-delivery Nano-systems	22
Pathogenic Mechanisms and Therapeutic Approaches of Intestinal Flora in the Immune Microenvironment of Hepatocellular Carcinoma	22
How does the Immunological System Change during the SARS-COV-2 Attack? A Clue for the New Immunotherapy Discovery	22
The ATP-dependent Pathways and Human Diseases	22
Opioid-Free Anaesthesia Improves Anaesthesia Recovery when Compared with that of Opioid-Based Anaesthesia. Systematic Review and Meta-Analysis of Clinical Trials	22
A Comprehensive Review on the State of the Art of Breast Cancers in Italy	22
Immunotherapy of Human Melanoma: Past, Present, Future	22
CD155-TIGIT Axis as a Therapeutic Target for Cancer Immunotherapy	22
Screening of Medicinal and Edible Homology Substances for Diabetic Kidney Disease Based on GraphBAN	22
Technetium-99m Radiolabeled Carboplatin Polymeric Nanoparticles for Imaging and Treatment of Epithelial Ovarian Cancer	21
Association between Maternal Hypertension and Cleft Lip and Palate: A Mendelian Randomization Study	21
Mechanisms of the Quorum Sensing Systems of Pseudomonas aeruginosa: Host and Bacteria	21
Free Fatty Acid Receptors (FFARs): Emerging Therapeutic Targets for the Management of Diabetes Mellitus	21
Multi-Target Synergy of Coridius chinensis in Testicular Aging via Network Pharmacology-Metabolomics Integration	21
Exploring the Toxicological Impact and Mechanisms of DEHP Exposure on Prostate Cancer Through Network Toxicology and Machine Learning Algorithms	21
Crosstalk between Oxidative Stress and Inflammation Induced by Ionizing Radiation in Healthy and Cancerous Cells	21
Predicting Clinical Prognosis and Treatment Response in Glioblastoma Based on Gene Replication Stress-Related Features	20
AlphaFold3: A Transformer in Life Sciences	20
Tribute to the Late Prof. Wolfgang Voelter – A Revered World-Class Scientist	20
LncRNA XIST: A Breakthrough in Inflammation-related Diseases	20
Oxadiazole Derivatives as Anticancer and Immunomodulatory Agents: A Systematic Review	20
C-KIT Receptor Inhibition as a Promising Approach to Design Anticancer Drugs	20
Classifying Molecular Subtypes and Establishing a Prognosis Model using Oxidative Stress-related Genes for Lung Adenocarcinoma	20
Construction of a PANoptosis-related Prognostic Signature for Predicting Prognosis, Tumor Microenvironment, and Immune Response in Ovarian Cancer	20
Meet the Editorial Board Member	20
Advances in Medicinal Chemistry: From Cancer to Chronic Diseases (Part I)	20
The Metformin Immunoregulatory Actions in Tumor Suppression and Normal Tissues Protection	20
Meet the Editorial Board Member	20
Hybrid and Conjugate Drugs and their Antimicrobial, Antiparasitic, Antiamoebic, Antileishmanial, Antiprotozoal, and Antitrypanosomal Properties	20
The Role and Therapeutic Potential of Non-coding RNAs in Resistance to EGFR - TKIs Targeted Therapy for Non-small Cell Lung Cancer	19
A Prognostic Lysine Crotonylation Signature Shapes the Immune Microenvironment in Hepatocellular Carcinoma	19
Comprehensive Structural and Functional Characterization of a Seed γ-thionin as a Potent Bioactive Molecule Against Fungal Pathogens and Insect Pests	19
Organoselenium-based Azomethines as Apoptosis Inducers in Colorectal Carcinoma via P53, BAX, Caspase-3, Caspase-6, and Caspase-9 Modulations	19
Protective Role and Mechanism of Action of Garlic in Organ Ischemia-reperfusion Injury: Where do we Stand?	19
Analysis of the Mechanism Underlying Radiotherapy Resistance Caused by Oligodendroglia Cells in Glioblastoma by Applying the Single-cell RNA Sequencing Technology	18
A Molecular Dynamic Simulation, Structural Analysis, and Ex Vivo Insights into the P-glycoprotein Mediated Interactions of Dietary Polyphenols with Cyclin-dependent Kinase Inhibitors: A Potential Stra	18
TRIM65 Suppresses oxLDL-induced Endothelial Inflammation by Interaction with VCAM-1 in Atherogenesis	18
Therapeutic Strategies to Improve the Treatment of Pleural Mesothelioma	18
Integrated Bioinformatics Analysis and Machine Learning to Identify Biomarkers and Fibroblast-related Features of Idiopathic Pulmonary Fibrosis	18
FHL1 Inhibition by miR-1301-3p Promotes Uterine Corpus Endometrial Carcinoma Cell Proliferation and Migration: A Prognostic Insight	18
Ninety Years of Pentamidine: The Development and Applications of Pentamidine and its Analogs	18
Nanomedicine in Management of Cerebral Infarction and Brain Cancer: Role of Inflammation	17
Comprehensive Assessment of Overactive Bladder (OAB) Treatment: Balancing Efficacy, Side Effects, and Quality of Life	17
Regulatory Non-coding RNAs Involved in Oxidative Stress and Neuroinflammation: An Intriguing Crosstalk in Parkinson’s Disease	17
Differential Effect of 4H-Benzo[d] [1, 3]oxazines on the Proliferation of Breast Cancer Cell Lines	17
Metabolome Profiling of Malignant Ascites Identifies Candidate Metabolic Biomarkers of Hepatocellular Carcinoma	17
Performance of Green Desymmetrization Methods toward Bioactive Cephalostatin Analogues	17
Therapeutic Role of HAT Therapy in Sepsis: A Systematic Review and Meta-Analysis	17
Highly Efficient and Eco-friendly Synthesis and Bio-activities of 1,3-benzazoles as Cu (II) Chelators in Alzheimer’s Disease Therapy	17
New Insights into Cold Shock Proteins Effects in Human Cancer: Correlation with Susceptibility, Prognosis and Therapeutical Perspectives	17
Telmisartan Inhibits Non-Small Cell Lung Cancer by Inducing Ferroptosis through the NRF2/GPX4 Signaling Axis	17
Genetic and Molecular Mechanisms Linking Breast Cancer to Meningioma Risk: Roles of EXO1, BRCA2, and ESR1	17
An Updated Comprehensive Pharmacovigilance Study of Drug- Induced Breast Cancer Based on FDA Adverse Event Reporting System Data	17
Meet the Editorial Board Member	16
Comprehensive scRNA-seq Analysis and Identification of CD8_+T Cell Related Gene Markers for Predicting Prognosis and Drug Resistance of Hepatocellular Carcinoma	16
The Emerging Role of N-Acetylcysteine in Psychiatry: A Narrative Review of Available Data	16
Berberine as an Antimicrobial Agent and Gut Microbiota Modulator: Mechanisms and Therapeutic Potential	16
Clinical Evidence of Interaction between Nutraceutical Supplementation and Platinum-based Chemotherapy	16
Multi-targeted HDAC Inhibitors as Anticancer Agents: Current Status and Future Prospective	16
Sleep Disturbances Associated with Different Systems of the Body: Underlying Mechanisms Involved and Consequences	16
Research Progress of Grapefruit-derived Extracellular Vesicles in Anti-tumor Treatment	16
The Association between High-density Lipoproteins and Periodontitis	16
Drug Delivery Systems based on Microneedles for Dermatological Diseases and Aesthetic Enhancement	16
Retinal Degeneration: Molecular Mechanisms and Therapeutic Strategies	16
Synthesis, Characterization, Anti-Proliferative Activity, Cell Cycle Analysis, and Annexin V-FITC Apoptosis Study of New Thiazole Derivatives	16
Benzoxazine: A Privileged Scaffold in Medicinal Chemistry	16
Identification and Experimental Validation of PLAC8 as a Biomarker for Follicular Lymphoma	16
Protective Roles and Therapeutic Effects of Gallic Acid in the Treatment of Cardiovascular Diseases: Current Trends and Future Directions	16
Apolipoprotein A-1 as a Potential Biomarker for Solid Tumors: A Systematic Review and Meta-Analysis	16
Oxymatrine Synergizes with 5-fluorouracil to Inhibit the Proliferation of A549 Cells by Targeting APE1	16
Celiac Disease Enzyme Therapy: Why Is There Still No Approved Drug?	16
The Effect of Probiotics on Oxidized LDL Levels: A Systematic Review and Meta-Analysis of Clinical Trials	15
Renal Effects of Empagliflozin in Patients with Type 2 Diabetes Mellitus	15
WITHDRAWN: Evaluation of Circadian Rhythm-related Genes for Prognosis Modeling and Immune Characterization in Thyroid Cancer	15
A Systematic Review and Meta-Analysis on the Effect of Flavonoids on Insulin-like Growth Factor and Insulin-like Growth Factor Binding Protein and Incidence of Breast Cancer	15
Neutrophil/Lymphocyte, Platelet/Lymphocyte, and Monocyte/Lymphocyte Ratios in Mood Disorders	15
Does Eta Protein Differentiate Rheumatoid Arthritis from Psoriatic Arthritis?	15

Meet the Country Editor	15
C-Reactive Protein Velocity in Patients with ST-elevation Myocardial Infarction: Rethinking a Traditional Biomarker	15
Advances in the Discovery of Novel Inhaled PI3Kδ Inhibitors for the Treatment of Asthma	15
Significance of Aneuploidy in Predicting Prognosis and Treatment Response of Uveal Melanoma	15
Melatonin: Novel Insights in the Treatment of Neurodegenerative Diseases	15
3D-QSAR Studies on High-affinity Phosphodiestera	15
Advancements in CDK-based Dual-target Inhibitors for Cancer Therapy	15
Meet the Editorial Board Member	15
Potential Mechanisms of COVID-19 Related Nervous System Damage and Effects on Female Fertility	15
Mechanism Exploration of Astaxanthin in the Treatment of Adriamycin-induced Cardiotoxicity based on Network Pharmacology and Experimental Validation	15
Melatonin in Reproductive Medicine: A Promising Therapeutic Target?	15
Mapping the Multifaceted Roles of ZNF280A: Insights into Prognosis, Immunity, and Function Across Pan-Cancer	15
An Advanced Network Pharmacology Study Reveals the Multi-Pathway and Multi-Gene Regulatory Mechanism of Jinbai Heat-clearing Prescription in HPV-induced Cervical Cancer via Molecular Docking and Micro	15
Recent Advances in Protein Folding Pathway Prediction through Computational Methods	14
Mycobacterial Targets for Thiourea Derivatives: Opportunities for Virtual Screening in Tuberculosis Drug Discovery	14
Surgical Advancements, Immunotherapy, Targeted and Conventional Therapies, Biopsy, Colposcopy, and Pap Smear Integration in the Management of Cervical Cancer	14
Mitochondrial Dysfunction in MASLD: Unveiling Mechanisms and Optimizing Therapeutic Strategies	14
Novel Small Molecule Inhibitors of Cyclin-dependent Kinases as Anticancer Agents	14
Side Effects of Alzheimer's Disease Treatment	14
Metformin Protects Human Insulin from Fructosylation: An In Vitro Biochemical Study	14
Medical Artificial Intelligence: Opportunities and Challenges In Infectious Disease Management	14
Anti-inflammatory Drug Combination Therapy for Atherosclerosis: Colchicine and Fenofibrate	14
Structure-Based Identification of Natural Product-Derived BCL-2 Inhibitors as Potential Therapeutics for Hepatocellular Carcinoma	14
Current Applications and Benefits of Polymeric Nanocarriers for the Management of Skin Disorders	14
Synthesis of Bis-thiazoles Tethered 1,4-Dihydropyridine and Pyridine Linkers via Simple Oxidation and their Molecular Docking as VEGFR -TK Inhibitors	14
Chemical Synthesis and Enzymatic Modification of Mangostins: A Comprehensive Review on Structural Modifications for Drug Discovery	14
Mendelian Randomization Analyses Indicate a Causal Association Between Sodium-Glucose Cotransporter-1 Inhibition and Mitochondrial Function	14
Interdisciplinary Frontiers in Medicinal Chemistry: Nanomedicine, Photodynamic Therapy, and Computational Drug Design	14
Astaxanthin as an Anticancer Agent against Breast Cancer: An In Vivo and In Vitro Investigation	14
LNX1-AS2 as a Key Prognostic and Immunotherapy Response Biomarker for Lung Adenocarcinoma	14
Enlightening the Mechanism of Ferroptosis in Epileptic Heart	14
Research Advances in the Structural Characterization and Biological Activity Assessment of Neocryptotanshinone	14
Gold Nanoparticles in Triple-Negative Breast Cancer Therapeutics	13
Clinical Significance of RBM15 in Gastric Cancer: A Multi-Database Validation	13
Defective Mitophagy Impairs Response to Inflammatory Activation of Macrophage-Like Cells	13
An In Vitro Laboratory Exploration Revealed the Antitumor Effects of Melittin on Osteosarcoma Cells	13
Application of Nanomedicine in Tumor Targeting Inflammatory Pathway	13
Cinnamaldehyde for the Treatment of Microbial Infections: Evidence Obtained from Experimental Models	13
Statins and Portal Hypertension: A Systematic Review and Meta-analysis of Randomized Controlled Trials	13
Vincristine in Cancer Therapy: Mechanisms, Efficacy, and Future Perspectives	13
Exploring the Potential of Nuciferine in Diabetes Management via PTGS2 Pathway Targeting by Network Analysis and In Silico Modeling Approach	13
AI: A New Solution for Old Issues of Carotid Atherosclerotic Plaque	13
Meet the Editorial Board Member	13
Repurposing Small-molecule Inhibitors against Bunyaviruses: Advances, Mechanisms, and Therapeutic Prospects	13
Natural Plant Materials as a Source of Neuroprotective Peptides	13
Acute Post-Streptococcal Glomerulonephritis in Children: A Comprehensive Review	13
Cardiac Organoids: A 3D Technology for Disease Modeling and Drug Screening	13
Research Progress on Antiviral Activity of Heparin	13
iACVP-MR: Accurate Identification of Anti-coronavirus Peptide based on Multiple Features Information and Recurrent Neural Network	13
TLR2 Activation as a Marker of Severe COVID-19 and a Potential Therapeutic Target	12
FOXN3-AS1: A Candidate Prognostic Marker and Epigenetic Target with Immunotherapeutic Implications in Acute Myeloid Leukemia	12
The Function of Autophagy in the Initiation, and Development of Breast Cancer	12
Research Progress of Microneedles in Vaccine Delivery	12
Selenium-containing Peptides and their Biological Applications	12
A Novel Acidic Polysaccharide from Inonotus obliquus (IOP-1) Suppresses Growth and Induces Apoptosis in Non-Small Cell Lung Cancer both In Vitro and In Vivo	12
Immunogenic Cell Death-relevant Molecular Patterns, Prognostic Genes, and Implications for Immunotherapy in Ovarian Cancer	12
Aptamers and New Bioreceptors for the Electrochemical Detection of Biomarkers Expressed in Hepatocellular Carcinoma	12
The Role of Antioxidants in Child Eye Health with a Focus on Myopia	12
Reactive Oxygen Species-Responsive Drug Delivery Systems: A New Approach in Nanomedicine	12
Developing a RiskScore Model based on Angiogenesis-related lncRNAs for Colon Adenocarcinoma Prognostic Prediction	12
Advances and Prospects of Ultrasound Targeted Drug Delivery Systems Using Biomaterial-modified Micro/Nanobubbles for Tumor Therapy	12
Epithelial to Mesenchymal Transition as a Therapeutic Target for MicroRNAs in Triple Negative Breast Cancer	12
Nutraceuticals in the Treatment of Inflammatory Bowel Disease: How the Panorama has Changed in the Last Decade?	12
Maximizing ISRIB Potential Requires Addressing Specificity, Long-term Safety, and Disease-specific Considerations	12
Is Oxidized Low-Density Lipoprotein a Principal Actor in Atherogenesis?	12
miR-26a is a Key Therapeutic Target with Enormous Potential in the Diagnosis and Prognosis of Human Disease	12
Current Overview on the Potency of Natural Products for Modulating Myeloid-derived Suppressor Cells Dependent Cold Tumors	12
Exploring the Multitarget Therapeutic Potential of Mangostin Derivatives	12
Neuroprotective Potential of Curcuminoids in Modulating Alzheimer’s Disease via Multiple Signaling Pathways	12
Recent Trends in Rationally Designed Molecules as Kinase Inhibitors	12
Mitochondrial Translocation of P66Shc Aggravates Cisplatin-induced AKI by Promoting Ferroptosis	12
Exploring Natural Analgesics for Chronic Pain Management: Cannabinoids and other Phytoconstituents	12
A Promising Druggable Target for Translational Therapy of Ovarian Cancer: A Molecular Profiling of Therapeutic Innovations, Extracellular Vesicle Acquired Resistance, and Signaling Pathways	12
In Vivo Safety Assessment of AZT-derived Organochalcogen Compounds with Promising Antiviral Effects against SARS-Cov-2	12
Electrochemical Aptasensing for Lifestyle and Chronic Disease Management	12
Computational Analysis and in vitro Validation of the Anti-Prostate Cancer Activity of Sesamin from Sesamum indicum	11
Autophagy Inhibition and Sensitization to Cisplatin in Esophageal Cancer Stem-like Cells via All-trans Retinoic Acid-induced miR-30a	11
Research Progress in the Clinical Treatment of Familial Hypercholesterolemia	11
An Immune Cell Activation Signature for Non - Small Cell Lung Cancer Revealed Tumor Microenvironment Heterogeneity and the Role of RORA in Regulating ZNF490/NDUFA12 Axis	11
SGLT2 Inhibitors and Kidney Diseases: A Clinical Perspective	11
Therapeutic and Diagnostic Agents based on Bioactive Endogenous and Exogenous Coordination Compounds	11
Innate Immunity Disorders in Non-Infectious Inflammatory Diseases	11
Ancient Wheat as Promising Nutraceuticals for the Prevention of Chronic and Degenerative Diseases	11
Identification of Key Genes and Signaling Pathways in Entrectinibresistant Non-small Cell Lung Cancer Using Bioinformatic Analysis and Experimental Verification	11
Urinary miRNAs and Prostate Cancer: Is there a Crossover Point Eventually, and where should we Head?	11
Plasma Proteins Mediate the Causal Effect of Diet on the Development of Osteoporosis: A Mendelian Randomization Study	11
Design, Synthesis, Docking Studies, and Biological Activity of Novel Analogs of Cyclophosphamide as Potential Anticancer Agents	11
Development of Neuroprotective Agents for the Treatment of Alzheimer's Disease using Conjugates of Serotonin with Sesquiterpene Lactones	11
Natural Phenolic Compounds with Antithrombotic and Antiplatelet Effects: A Drug-likeness Approach	11
Nanomedicine for Cancer	11
LncRNA-associated ceRNA Network Revealing the Potential Regulatory Roles of Ferroptosis and Immune Infiltration in Osteosarcoma as well as Construction of the Prognostic Model	11
PROTACs Targeting Molecular Targets in Triple-Negative Breast Cancer	11
Azole Homodimers as Promising Antifungal Agents: Synthesis, Biological Activity Evaluation and Molecular Modeling	11
Role of Fyn Kinase Inhibitors in Switching Neuroinflammatory Pathways	11
NADPH Oxidase: A Potential Therapeutic Target to Reduce Primary Sclerosis Cholangitis Following Liver Transplantation	11