OOIR: Observatory of International Research

Papers

(The H4-Index of Current Medicinal Chemistry is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Corrigendum to: Update of the Preclinical Situation of Anticancer Platinum Complexes: Novel Design Strategies and Innovative Analytical Approaches	108
Challenges of Natural Anticancer and Anti-inflammatory Agents	93
Identification of Critical Genes Related to Breast Cancer with Brain Metastasis Through Bioinformatics Analysis	77
Construction and Biological Evaluation of Different Nanoshell Thickness Ni@SiO₂ Nanotubes as Good Protein Separation Carriers for Bovine Hemoglobin	58
Ferroptosis Inducers for Prostate Cancer Therapy	56
Intermittent Fasting and Fasting-mimicking Diet: Promising Strategies in Cancer Management	55
An Updated Review Deciphering Apigenin Nanostructures as Promising Therapeutic Efficiency in Human Carcinomas	54
Integrating Transcriptomic Data and Mendelian RandomizationAnalyses Reveals Potentially Novel Sepsis-related Targets	53
Multimodality Cardiac Imaging Biomarkers and Atrial Fibrillation Substrate: Are they Worthwhile?	52
Drug-Resistant Infections: A Global Challenge for the Future	51
Paneth Cells: Recent Updates on Elucidating Therapeutic Implications in Gastroenterological Disease Management	51
Potential for Novel Therapeutic Uses of Alpha Lipoic Acid	48
Long Non-coding RNA DLGAP1-AS1 and DLGAP1-AS2: Two Novel Oncogenes in Multiple Cancers	44
Commentary on the Role of Medicinal Cannabis in Healthy Aging and Neuroprotection	44
Long Non-coding RNA SNHG16 Facilitates Esophageal Cancer Cell Proliferation and Self-renewal through the microRNA-802/PTCH1 Axis	42
Chalcogenium-AZT Derivatives: A Plausible Strategy To Tackle The RT-Inhibitors-Related Oxidative Stress While Maintaining Their Anti- HIV Properties	42
Research Prospects for the Mitochondria in Glaucoma: A Bibliometric Analysis	41
Mitochondrial DNA Mutations in Colorectal Cancer Stem Cells: Implications for Tumor Dynamics and Therapeutic Strategies	41
Expression of TCEAL2 is a Novel Prognostic Biomarker and Potential Therapeutic Target in Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma	40
MEF2C is a Potential Prognostic Biomarker and is Correlated with Immune Infiltrates in Lung Adenocarcinoma	40
Analysis and Validation of Tyrosine Metabolism-related Prognostic Features for Liver Hepatocellular Carcinoma Therapy	38
Clinical Application and Synthesis Methods of Deuterated Drugs	38
New Insights into the Long Non-coding RNAs Dependent Modulation of Heart Failure and Cardiac Hypertrophy: From Molecular Function to Diagnosis and Treatment	38
Potential Therapeutic Targets for the Management of Diabetes Mellitus Type 2	38
Serine Protease 27, a Prognostic Biomarker in Pan-cancer and Associated with the Aggressive Progression of Breast Cancer	37

Exploring the Anticancer Potential of Astragalin in Triple Negative Breast Cancer Cells by Attenuating Glycolytic Pathway through AMPK/mTOR	36
Role of Flavonoids in Management of Various Biological Targets in Alzheimer’s Disease: Evidence from Preclinical to Clinical Studies	36
Activating Protein-1 (AP-1): A Promising Target for the Treatment of Fibrotic Diseases	34
ANGPTL4-the Link Binding Lipid Metabolism and Inflammation	34
Ganaxolone: First FDA-approved Medicine for the Treatment of Seizures Associated with Cyclin-dependent Kinase-like 5 Deficiency Disorder	33
Recent Advances in Lung Cancer Therapy Based on Nanomaterials: A Review	33
Intimal Macrovascular Pericytes: Their Role in Vascular Biology and Atherogenesis	32
Neuroinflammatory Human Brain Organoids Enable Comprehensive Drug Screening Studies: Fingolimod and its Analogues in Focus	32
Integrated Exploration of Pyranocoumarin Derivatives as Synergistic Inhibitors of Dual-target for Mpro and PLpro Proteins of SARS-CoV- 2 through Molecular Docking, ADMET Analysis, and Molecular Dynami	32
SGLT-2 Inhibitors: The Next-generation Treatment for Type 2 Diabetes Mellitus	32
Prediction of Prognosis and Immunotherapy Response of Gastric Cancer Based on Glutamine Metabolism-related Genes	32