OOIR: Observatory of International Research

Papers

(The H4-Index of Current Medicinal Chemistry is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and other Drugs for the Treatment of the New Coronavir	212
Metal-Organic Framework (MOF)-Based Drug Delivery	148
Aptamer-Based Targeted Drug Delivery Systems: Current Potential and Challenges	122
Recent Research on Flavonoids and their Biomedical Applications	119
Zeolitic Imidazolate Frameworks (ZIF-8) for Biomedical Applications: A Review	118
Antimicrobial Capacity of Plant Polyphenols against Gram-positive Bacteria: A Comprehensive Review	103
Bioactive Secondary Metabolites from Endophytic Fungi	98
Osteoporosis: Mechanism, Molecular Target and Current Status on Drug Development	96
Comprehensive Review on Graphene Oxide for Use in Drug Delivery System	85
Recent Progress in Histone Deacetylase Inhibitors as Anticancer Agents	80
The Role of Zinc and Copper in Insulin Resistance and Diabetes Mellitus	75
Acyclovir in the Treatment of Herpes Viruses – A Review	72
Natural Polymer-based Stimuli-responsive Hydrogels	71
The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications	69
Antiviral Activities of Human Host Defense Peptides	67
A Review: The Anti-inflammatory, Anticancer and Antibacterial Properties of Four Kinds of Licorice Flavonoids Isolated from Licorice	59
Ferroptosis: A Novel Mechanism of Artemisinin and its Derivatives in Cancer Therapy	59
A Systematic Review on Anti-diabetic Properties of Chalcones	57
The Application of Hydrogels Based on Natural Polymers for Tissue Engineering	56
The Role of Matrix Gla Protein (MGP) in Vascular Calcification	54
The “Big Five” Phytochemicals Targeting Cancer Stem Cells: Curcumin, EGCG, Sulforaphane, Resveratrol and Genistein	54
Targeting n-3 Polyunsaturated Fatty Acids in Non-Alcoholic Fatty Liver Disease	52
The Role of Tumor Associated Macrophages (TAMs) in Cancer Progression, Chemoresistance, Angiogenesis and Metastasis - Current Status	50
Natural Polymers Based Hydrogels for Cell Culture Applications	48
B7-H3 Immune Checkpoint Protein in Human Cancer	47

Cyclosporine A: Chemistry and Toxicity – A Review	45
Exosomes and Lung Cancer: Roles in Pathophysiology, Diagnosis and Therapeutic Applications	45
Advances in Pharmacological Activities and Mechanisms of Glycyrrhizic Acid	45
Anti-Coronavirus Vaccines: Past Investigations on SARS-CoV-1 and MERS-CoV, the Approved Vaccines from BioNTech/Pfizer, Moderna, Oxford/AstraZeneca and others under Development Against SARSCoV- 2 Infec	44
Anti-tumor Effects of Curcuminoids in Glioblastoma Multiforme: An Updated Literature Review	44
FTY720 (Fingolimod) Ameliorates Brain Injury through Multiple Mechanisms and is a Strong Candidate for Stroke Treatment	44
Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints	44
Role of Pro-inflammatory Cytokines in Regulation of Skeletal Muscle Metabolism: A Systematic Review	43
Inflammation as the Common Biological Link Between Depression and Cardiovascular Diseases: Can Carnosine Exert a Protective Role?	43
Natural COX-2 Inhibitors as Promising Anti-inflammatory Agents: An Update	43
A Comprehensive Review on Oxysterols and Related Diseases	42
Recent Progress of Benzimidazole Hybrids for Anticancer Potential	41
Deep Learning in Drug Target Interaction Prediction: Current and Future Perspectives	41
Central Regulatory Role of Cytokines in Periodontitis and Targeting Options	40
Terpenes, Phenylpropanoids, Sulfur and Other Essential Oil Constituents as Inhibitors of Cholinesterases	39