OOIR: Observatory of International Research

Papers

(The TQCC of Protein and Peptide Letters is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Effects of Glutathionylation on Guanylyltransferase Activity of NS5 N-terminal Capping Domain from Dengue, Japanese Encephalitis, and Zika Viruses	78
Amplification of Amyloid Protein-induced Aggregation of the Eukaryotic Ribosome	67
Structural Shifts of the Parvovirus B19 Capsid Receptor-binding Domain: A Peptide Study	39
FOXN3 Expression Regulated by miR-299-5p Inhibiting the Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma Cells	28
Acknowledgements to Reviewers	27
Molecular Interactions of the Antimicrobial Peptide Tritrpticin with Mixed Nanoaggregates: A Fluorescence Spectroscopy Study	26
Water-soluble Moringa oleifera Seed Lectin Exhibits Monoaminergic Pathway-linked Anti-depressive-like Effects in Mice	25
Hybrid 3D Bioprinted Scaffolds for the Delivery of Peptide Therapeutics	25
Recent Applications of Tissue-Engineered 3D Scaffolds in Oncology: Present and Future Perspectives	21
Effective Plant-Derived Proteins and Peptides in Leukemia Treatment	21
Potent Antioxidant and Antibacterial Activities of ≤3 kDa Hydrolyzed Sarcoplasmic Proteins from IPB-D1 Chicken	21
Heat-Shock Triggers Inverted Induction of Hypo-S-Nitrosylation and Hyper-O-GlcNAcylation	19
Understanding Protein Functions in the Biological Context	19
An Overview of the Role of Membrane Proteins in Microbial Solvents Tolerance	18
Corrigendum to: Reviewing the Context of Molecular Modeling to Enhance the Application of Machine Learning Technologies for Safer Bioinformatics	17
The Implication of Hypocretin in Drug Abuse and Arousal in the Brain Stem	17
HSP90-regulated CHIP/TRIM21/p21 Axis Involves in the Senescence of Osteosarcoma Cells	17
Effect of Adipokinetic Hormone on Learning-Memory in a Scopolamine-Induced Alzheimer's Model in Mice	17
LanthMS: A Computational Tool for the Structure Elucidation of Lanthipeptides from Tandem Mass Spectrometry Data	17
Plasma/Serum Proteomics based on Mass Spectrometry	16
PLEKHG7 Expression: A Biomarker for Prognosis and Targeted Therapy in Diffuse Large B-cell Lymphoma	15
SNHG3/miR-330-5p/HSD11B1 Alleviates Myocardial Ischemia-reperfusion Injury by Regulating the ERK/p38 Signaling Pathway	15
LINC01836 Promotes Colorectal Cancer Progression and Functions as ceRNA to Target SLC17A9 by Sponging miR-1226-3p	15
ZP3 Expression in Pancreatic Adenocarcinoma: Its Implications for the Prognosis and Therapy	15
Inhibition of Canonical Wnt Signaling in Renal Cell Carcinoma Bone Metastasis: An Immunohistochemical Analysis of DKK1 and LRP5 Expression	15

Unraveling the Role of Functional Amyloids and Amyloid Peptides in Disease Detection	14
A Review of Gap Junction Protein and its Potential Role in Nervous System-Related Disease	13
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study	13
Comprehensive Analysis of lncRNA and mRNA Expression Profile of Macrophage RAW264.7 Stimulated by Antimicrobial Peptide BSN-37	13
Variable Surface Antigens of Plasmodium falciparum: Protein Families with Divergent Roles	13
Molecular Bases of Protein Antigenicity and Determinants of Immunogenicity, Anergy, and Mitogenicity	12
Association between Higher Expression of Vav1 in Hepatocellular Carcinoma and Unfavourable Clinicopathological Features and Prognosis	12
Trypsin/α-Amylase Inhibitors from Capsicum chinense Seeds: Characterization and Antifungal Activity against Fungi of Agronomic Importance	12
Unveiling the Molecular Mechanism of Diosmetin and its Impact on Multifaceted Cellular Signaling Pathways	12
A Review on Recent Advancement in Expression Strategies Used in Bacillus subtilis	11
Synthesis of Two Designed Hairprin Peptides on a Newly Developed 1,6-Hexanediol Diacrylate (HDODA)-Crosslinked Polystyrene Resin	11
Gelsolin Inhibits the Proliferation of Colon Cancer Cells by Enhancing the Expression of TNFR2/CASP10 as a Death Receptor Pathway	11
Binding of l-Anilino-8-Napthalenesulfonate to Free and Coformycin-Complexed Bovine Adenosine Deaminase	11
Targeting APE1: Advancements in the Diagnosis and Treatment of Tumors	11
UPBEAT1-ROS-POD-PAL System under Different Xylogenesis Scenarios in Karelian Birch (Betula pendula Roth var. carelica (Mercl.) Hämet-Ahti)	11
Neuropeptide Network of Polycystic Ovary Syndrome – A Review	10
Neuroprotective Effect of Dexmedetomidine Pretreatment on Sevoflurane- Initiated Neurotoxicity Via the Mir-204-5p/SOX4 Axis	10
Wogonin Restrains the Malignant Progression of Lung Cancer Through Modulating MMP1 and PI3K/AKT Signaling Pathway	9
P53-induced GAP-43 Upregulation in Primary Cortical Neurons of Rats	9
Guanidinium-based Integrated Peptide Dendrimers: Pioneer Nanocarrier in Cancer Therapy	9
Modified Levels of Renin Angiotensin Related Components in the Frontal Cortex and Hippocampus were Associated with Neuroinflammation and Lower Neuroprotective Effects of NGF During Acute Hepatic Encep	9
Preface	9
Cold-Induced RNA-Binding Protein and RNA-Binding Motif Protein 3: Two RNA Molecular Chaperones Closely Related to Reproductive Development and Reproductive System Diseases	9
Identifying the Role of Individual Seal IAPP Amino Acids in Inhibiting the Aggregation of Human IAPP	9
Dexmedetomidine Alleviates Brain Ischemia/Reperfusion Injury by Regulating Metastasis-associated Lung Adenocarcinoma Transcript 1/MicroRNA-140-5p/ Nuclear Factor Erythroid-derived 2-like 2 Axis	9
Knockdown of Programmed Death 1 Inhibited Progression of Papillary Thyroid Carcinoma in Mice	8
Structural and Functional Analysis of Urease Accessory Protein E from Vancomycin-Resistance Staphylococcus aureus MU50 Strain	8
Feasibility of Domain Segmentation of B19V VP1u Using Intein Technology for Structural Studies	8
Comparison of Adjuvant Effects of Montanide ISA-720 and Heat Shock Protein 27 in Increasing Immunostimulatory Properties of HIV-1 Nef-Vif Fusion Protein Construct	8
Thermodynamics of the Association of Aminoglycoside Antibiotics with Human Angiogenin	8
Screening of MMP-2 Inhibiting Phytoconstituents for the Development of Newer Pancreatic Cancer Treatment Modalities	8
Purification, Crystallization, and Preliminary X-ray Diffraction Studies on Hemoglobin from the Angora Goat (Capra Aegagrus Hircus)	8
Lessons Learnt and the Way Forward for Drug Development Against Isocitrate Lyase from Mycobacterium tuberculosis	8
Meclofenoxate Inhibits Aggregation of Alpha-synuclein in vitro	8
Preparation of IgE Antibody and Distribution of IgE+ Secretory Cells in the Palatine Tonsil of Bactrian Camel	8
Advances in Polymeric Drug Delivery Systems: From Biodegradability to Nanocarrier Technologies	7
Design of Artificial C-Peptides as Potential Anti-HIV-1 Inhibitors Based on 6-HB Formation Mechanism	7
Antimicrobial Peptides: An Overview of their Structure, Function and Mechanism of Action	7
Characterization of a Novel Thermostable 7α-Hydroxysteroid Dehydrogenase	7
Proteome-Wide Acetylome Profiling Suggests Extensive Aspirin-Driven Remodeling of Networks Relevant to THP-1 Macrophage Differentiation	7
Proteomic Analysis of Glucose-Induced Cardiac Myoblasts and the Potential Role of mir-92b-5p in Regulating Sarcomere Proteins Under a Hyperglycemic Environment	7
Expression and Purification of His-Tagged Variants of Human Hepatitis A Virus 3C Protease	7
Development of a Peptide-Based Multiepitope Vaccine from the SARS-CoV-2 Spike Protein for Targeted Immune Response Against COVID-19	7
The LL-37 Antimicrobial Peptide as a Treatment for Systematic Infection of Acinetobacter baumannii in a Mouse Model	7
Combining Network Pharmacology, Molecular Docking and Preliminary Experiments to Explore the Mechanism of Action of FZKA Formula on Non-small Cell Lung Cancer	7
In Silico Analysis of Natural Plant-Derived Cyclotides with Antifungal Activity against Pathogenic Fungi	7
Interaction of the Seed Lectin from Parkia Platycephala (Mimosoideae) with Carbohydrates and Complex Glycans	7
A Functional Human Glycogen Debranching Enzyme Encoded by a Synthetic Gene: Its Implications for Glycogen Storage Disease Type III Management	7
Applications of CRISPR Cas-9 in Ovarian Cancer Research	7
The Agonistic Activity of the Human Epidermal Growth Factor is Reduced by the D46G Substitution	7

Natural Amphibian-Derived Host Defense Peptides: Peptide Immunomodulators with Potential Therapeutic Value	7
Design, Synthesis and DNA-Binding Activities of GCN4 Peptide Dimer Studied by Circular Dichroism Spectroscopy	6
Concentration-mediated Folding and Unfolding of Collagen Triple Helix	6
Precision Enzyme: Targeted Drug Discovery in Neurodegenerative Disorders	6
Cyclopeptide-based Anti-liver Cancer Agents: A Mini-review	6
Optimizing Sleep in Athletes: The Potential of α-Lactalbumin in Nutrition Intervention	6
Analysis of the Interaction of UBE2Q1 with B4GALT1 and P53: Experimental and Molecular Modeling Study	6
The Roles of Ciliary Neurotrophic Factor - from Neuronutrition to Energy Metabolism	6
Disruption of Staphylococcus aureus Biofilms with Purified Moringa oleifera Leaf Extract Protein	6
Unlocking the Keratinolytic Potential of Brevibacillus agri Derived Keratinase: A Molecular Characterization Study	6
Exploring the Potential Long-term Impact of SARS-CoV-2 on Protein Misfolding and Amyloid-related Conditions	6
Expression, Purification, and Evaluation of Antibody Responses and Antibody-Immunogen Complex Simulation of a Designed Multi-Epitope Vaccine against SARS-COV-2	6
Participation of CWINV and SUS Genes in Sucrose Utilization in the Disruption of Cambium Derivatives Differentiation of Silver Birch	6
Some Minor Characteristics of Spectrophotometric Determination of Antioxidant System and Phenolic Metabolism Enzyme Activity in Wood Plant Tissues of Pinus sylvestris L.	6
Production of Soluble Murine TRAILs in Escherichia coli with Zn²⁺ Supplementation	6
Estrogen Sulfotransferase SULT1E1 Expression Levels and Regulated Factors in Malignant Tumours	6
MicroRNA-605-3p Inhibited the Growth and Chemoresistance of Osteosarcoma Cells via Negatively Modulating RAF1	6
Biocompatible Excipients from Microalgae: Advancing Protein and Peptide Therapeutics through Sustainable Formulation Strategies	6