OOIR: Observatory of International Research

Papers

(The TQCC of Protein and Peptide Letters is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Effects of Glutathionylation on Guanylyltransferase Activity of NS5 N-terminal Capping Domain from Dengue, Japanese Encephalitis, and Zika Viruses	62
The Sensitive Genes in Response to Various Metal Ion Stresses in the Yeast Saccharomyces cerevisiae	34
Amplification of Amyloid Protein-induced Aggregation of the Eukaryotic Ribosome	19
Structural Shifts of the Parvovirus B19 Capsid Receptor-binding Domain: A Peptide Study	16
Effective Plant-Derived Proteins and Peptides in Leukemia Treatment	15
Molecular Interactions of the Antimicrobial Peptide Tritrpticin with Mixed Nanoaggregates: A Fluorescence Spectroscopy Study	14
Heat-Shock Triggers Inverted Induction of Hypo-S-Nitrosylation and Hyper-O-GlcNAcylation	14
FOXN3 Expression Regulated by miR-299-5p Inhibiting the Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma Cells	14
HSP90-regulated CHIP/TRIM21/p21 Axis Involves in the Senescence of Osteosarcoma Cells	13
Water-soluble Moringa oleifera Seed Lectin Exhibits Monoaminergic Pathway-linked Anti-depressive-like Effects in Mice	13
Understanding Protein Functions in the Biological Context	13
Construction and Evaluation of Recombinant Chimeric Fibrillin and Elastin Fragment in Human Mesenchymal Stem Cells	12
Plasma/Serum Proteomics based on Mass Spectrometry	12
The Implication of Hypocretin in Drug Abuse and Arousal in the Brain Stem	11
Evaluation of the Anti-Liver Cancer Activity of Protein Fractions Isolated from Adenium obesum Leaf Extract	11
Effect of Adipokinetic Hormone on Learning-Memory in a Scopolamine-Induced Alzheimer's Model in Mice	11
LINC01836 Promotes Colorectal Cancer Progression and Functions as ceRNA to Target SLC17A9 by Sponging miR-1226-3p	11
An Overview of the Role of Membrane Proteins in Microbial Solvents Tolerance	11
The Application of a Recombinant Antimicrobial Peptide of Thrombocidin-1 Expressed in Pichia pastoris as a Novel Approach Against Some Oral Pathogenic Bacteria: An In Vitro Study	11
PLEKHG7 Expression: A Biomarker for Prognosis and Targeted Therapy in Diffuse Large B-cell Lymphoma	10
Unraveling the Role of Functional Amyloids and Amyloid Peptides in Disease Detection	10
Inhibition of Canonical Wnt Signaling in Renal Cell Carcinoma Bone Metastasis: An Immunohistochemical Analysis of DKK1 and LRP5 Expression	10
Current Trends and Applications of Food-derived Antihypertensive Peptides for the Management of Cardiovascular Disease	10
ZP3 Expression in Pancreatic Adenocarcinoma: Its Implications for the Prognosis and Therapy	10
Variable Surface Antigens of Plasmodium falciparum: Protein Families with Divergent Roles	9

SNHG3/miR-330-5p/HSD11B1 Alleviates Myocardial Ischemia-reperfusion Injury by Regulating the ERK/p38 Signaling Pathway	9
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study	9
A Review of Gap Junction Protein and its Potential Role in Nervous System-Related Disease	9
Comprehensive Analysis of lncRNA and mRNA Expression Profile of Macrophage RAW264.7 Stimulated by Antimicrobial Peptide BSN-37	9
Unveiling the Molecular Mechanism of Diosmetin and its Impact on Multifaceted Cellular Signaling Pathways	8
Human Serum Albumin Aggregation and its Modulation Using Nanoparticles: A Review	8
Molecular Bases of Protein Antigenicity and Determinants of Immunogenicity, Anergy, and Mitogenicity	8
Association between Higher Expression of Vav1 in Hepatocellular Carcinoma and Unfavourable Clinicopathological Features and Prognosis	8
Trypsin/α-Amylase Inhibitors from Capsicum chinense Seeds: Characterization and Antifungal Activity against Fungi of Agronomic Importance	8
Binding of l-Anilino-8-Napthalenesulfonate to Free and Coformycin-Complexed Bovine Adenosine Deaminase	8
Protein Tyrosine Phosphatase Receptor-type Q: Structure, Activity, and Implications in Human Disease	8
Synthesis of Two Designed Hairprin Peptides on a Newly Developed 1,6-Hexanediol Diacrylate (HDODA)-Crosslinked Polystyrene Resin	7
Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta	7
Targeting APE1: Advancements in the Diagnosis and Treatment of Tumors	7
Dexmedetomidine Alleviates Brain Ischemia/Reperfusion Injury by Regulating Metastasis-associated Lung Adenocarcinoma Transcript 1/MicroRNA-140-5p/ Nuclear Factor Erythroid-derived 2-like 2 Axis	7
Improved Soluble Expression in Escherichia coli and Easily Purified Recombinant Human Bone Morphogenetic 7-2 Fusion Protein	7
Gelsolin Inhibits the Proliferation of Colon Cancer Cells by Enhancing the Expression of TNFR2/CASP10 as a Death Receptor Pathway	7
UPBEAT1-ROS-POD-PAL System under Different Xylogenesis Scenarios in Karelian Birch (Betula pendula Roth var. carelica (Mercl.) Hämet-Ahti)	7
Neuroprotective Effect of Dexmedetomidine Pretreatment on Sevoflurane- Initiated Neurotoxicity Via the Mir-204-5p/SOX4 Axis	7
Guanidinium-based Integrated Peptide Dendrimers: Pioneer Nanocarrier in Cancer Therapy	7
Neuropeptide Network of Polycystic Ovary Syndrome – A Review	7
A Review on Recent Advancement in Expression Strategies Used in Bacillus subtilis	7
Knockdown of Programmed Death 1 Inhibited Progression of Papillary Thyroid Carcinoma in Mice	6
Thermodynamics of the Association of Aminoglycoside Antibiotics with Human Angiogenin	6
Structural and Functional Analysis of Urease Accessory Protein E from Vancomycin-Resistance Staphylococcus aureus MU50 Strain	6
Cold-Induced RNA-Binding Protein and RNA-Binding Motif Protein 3: Two RNA Molecular Chaperones Closely Related to Reproductive Development and Reproductive System Diseases	6
Preface	6
Identifying the Role of Individual Seal IAPP Amino Acids in Inhibiting the Aggregation of Human IAPP	6
Lessons Learnt and the Way Forward for Drug Development Against Isocitrate Lyase from Mycobacterium tuberculosis	6
Regulatory Mechanism of lncRNA CTBP1-AS2 in Nasopharyngeal Carcinoma Cell Proliferation and Apoptosis via the miR-140-5p/BMP2 Axis	6
P53-induced GAP-43 Upregulation in Primary Cortical Neurons of Rats	6
Methods of PARP-1 Determination and its Importance in Living Organisms	6
Wogonin Restrains the Malignant Progression of Lung Cancer Through Modulating MMP1 and PI3K/AKT Signaling Pathway	6
Meclofenoxate Inhibits Aggregation of Alpha-synuclein in vitro	6
Development of a Peptide-Based Multiepitope Vaccine from the SARS-CoV-2 Spike Protein for Targeted Immune Response Against COVID-19	5
Effect of Propeptide Mutations on the Directed Evolution of Rhizomucor miehei Lipase	5
Modified Levels of Renin Angiotensin Related Components in the Frontal Cortex and Hippocampus were Associated with Neuroinflammation and Lower Neuroprotective Effects of NGF During Acute Hepatic Encep	5
Improving Acid-Base Pair Concentration in Wash/Elution Buffer Eliminates Elution Peak-Shouldering in Cation Exchange Chromatography	5
Characterization of a Novel Thermostable 7α-Hydroxysteroid Dehydrogenase	5
Expression and Purification of His-Tagged Variants of Human Hepatitis A Virus 3C Protease	5
Feasibility of Domain Segmentation of B19V VP1u Using Intein Technology for Structural Studies	5
Insights into Coronavirus Papain-like Protease Structure, Function and Inhibitors	5
Unidentified N-glycans by N-glycosidase A were Identified by Nglycosidase F under Denaturing Conditions in Plant Glycoprotein	5
Comparison of Adjuvant Effects of Montanide ISA-720 and Heat Shock Protein 27 in Increasing Immunostimulatory Properties of HIV-1 Nef-Vif Fusion Protein Construct	5
Purification, Crystallization, and Preliminary X-ray Diffraction Studies on Hemoglobin from the Angora Goat (Capra Aegagrus Hircus)	5
Screening of MMP-2 Inhibiting Phytoconstituents for the Development of Newer Pancreatic Cancer Treatment Modalities	5
Preparation of IgE Antibody and Distribution of IgE+ Secretory Cells in the Palatine Tonsil of Bactrian Camel	5
Design, Synthesis and DNA-Binding Activities of GCN4 Peptide Dimer Studied by Circular Dichroism Spectroscopy	4
Proteomic Analysis of the Colistin-resistant E. coli Clinical Isolate: Explorations of the Resistome	4
MicroRNA-605-3p Inhibited the Growth and Chemoresistance of Osteosarcoma Cells via Negatively Modulating RAF1	4

Optimizing Sleep in Athletes: The Potential of α-Lactalbumin in Nutrition Intervention	4
Cyclopeptide-based Anti-liver Cancer Agents: A Mini-review	4
In Silico Analysis of Natural Plant-Derived Cyclotides with Antifungal Activity against Pathogenic Fungi	4
Anticancer and Antimicrobial Evaluations on Alternative Reading Frame (ARF) Peptides and their Derivatives	4
Interaction of the Seed Lectin from Parkia Platycephala (Mimosoideae) with Carbohydrates and Complex Glycans	4
Participation of CWINV and SUS Genes in Sucrose Utilization in the Disruption of Cambium Derivatives Differentiation of Silver Birch	4
Antimicrobial Peptides: An Overview of their Structure, Function and Mechanism of Action	4
Design of Artificial C-Peptides as Potential Anti-HIV-1 Inhibitors Based on 6-HB Formation Mechanism	4
Combining Network Pharmacology, Molecular Docking and Preliminary Experiments to Explore the Mechanism of Action of FZKA Formula on Non-small Cell Lung Cancer	4
Some Minor Characteristics of Spectrophotometric Determination of Antioxidant System and Phenolic Metabolism Enzyme Activity in Wood Plant Tissues of Pinus sylvestris L.	4
Expression, Purification, and Evaluation of Antibody Responses and Antibody-Immunogen Complex Simulation of a Designed Multi-Epitope Vaccine against SARS-COV-2	4
Analysis of the Interaction of UBE2Q1 with B4GALT1 and P53: Experimental and Molecular Modeling Study	4
Production of Soluble Murine TRAILs in Escherichia coli with Zn²⁺ Supplementation	4
A Functional Human Glycogen Debranching Enzyme Encoded by a Synthetic Gene: Its Implications for Glycogen Storage Disease Type III Management	4
Preface	4
Precision Enzyme: Targeted Drug Discovery in Neurodegenerative Disorders	4
The Agonistic Activity of the Human Epidermal Growth Factor is Reduced by the D46G Substitution	4
The LL-37 Antimicrobial Peptide as a Treatment for Systematic Infection of Acinetobacter baumannii in a Mouse Model	4
Disruption of Staphylococcus aureus Biofilms with Purified Moringa oleifera Leaf Extract Protein	4
Concentration-mediated Folding and Unfolding of Collagen Triple Helix	4
Unlocking the Keratinolytic Potential of Brevibacillus agri Derived Keratinase: A Molecular Characterization Study	4
Estrogen Sulfotransferase SULT1E1 Expression Levels and Regulated Factors in Malignant Tumours	4
Proteomic Analysis of Glucose-Induced Cardiac Myoblasts and the Potential Role of mir-92b-5p in Regulating Sarcomere Proteins Under a Hyperglycemic Environment	4
Process Development for the Production and Purification of PEGylated RhG-CSF Expressed in Escherichia coli	4
Structural Analysis Revealed the Interaction of Cardenolides from Calotropis procera with Na+/K+ ATPases from Herbivores	4
The Roles of Ciliary Neurotrophic Factor - from Neuronutrition to Energy Metabolism	4
Natural Amphibian-Derived Host Defense Peptides: Peptide Immunomodulators with Potential Therapeutic Value	4
Applications of CRISPR Cas-9 in Ovarian Cancer Research	4