Protein and Peptide Letters

Article	Citations
Effects of Glutathionylation on Guanylyltransferase Activity of NS5 N-terminal Capping Domain from Dengue, Japanese Encephalitis, and Zika Viruses	69
Amplification of Amyloid Protein-induced Aggregation of the Eukaryotic Ribosome	44
Structural Shifts of the Parvovirus B19 Capsid Receptor-binding Domain: A Peptide Study	38
FOXN3 Expression Regulated by miR-299-5p Inhibiting the Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma Cells	28
Understanding Protein Functions in the Biological Context	24
Acknowledgements to Reviewers	20
Heat-Shock Triggers Inverted Induction of Hypo-S-Nitrosylation and Hyper-O-GlcNAcylation	20
Molecular Interactions of the Antimicrobial Peptide Tritrpticin with Mixed Nanoaggregates: A Fluorescence Spectroscopy Study	19
Effective Plant-Derived Proteins and Peptides in Leukemia Treatment	19
Recent Applications of Tissue-Engineered 3D Scaffolds in Oncology: Present and Future Perspectives	18
Hybrid 3D Bioprinted Scaffolds for the Delivery of Peptide Therapeutics	17
Water-soluble Moringa oleifera Seed Lectin Exhibits Monoaminergic Pathway-linked Anti-depressive-like Effects in Mice	16
Potent Antioxidant and Antibacterial Activities of ≤3 kDa Hydrolyzed Sarcoplasmic Proteins from IPB-D1 Chicken	16
ZP3 Expression in Pancreatic Adenocarcinoma: Its Implications for the Prognosis and Therapy	15
Inhibition of Canonical Wnt Signaling in Renal Cell Carcinoma Bone Metastasis: An Immunohistochemical Analysis of DKK1 and LRP5 Expression	15
LINC01836 Promotes Colorectal Cancer Progression and Functions as ceRNA to Target SLC17A9 by Sponging miR-1226-3p	14
Corrigendum to: Reviewing the Context of Molecular Modeling to Enhance the Application of Machine Learning Technologies for Safer Bioinformatics	14
Plasma/Serum Proteomics based on Mass Spectrometry	14
Effect of Adipokinetic Hormone on Learning-Memory in a Scopolamine-Induced Alzheimer's Model in Mice	13
PLEKHG7 Expression: A Biomarker for Prognosis and Targeted Therapy in Diffuse Large B-cell Lymphoma	13
Current Trends and Applications of Food-derived Antihypertensive Peptides for the Management of Cardiovascular Disease	13
An Overview of the Role of Membrane Proteins in Microbial Solvents Tolerance	13
HSP90-regulated CHIP/TRIM21/p21 Axis Involves in the Senescence of Osteosarcoma Cells	13
The Implication of Hypocretin in Drug Abuse and Arousal in the Brain Stem	13
Comprehensive Analysis of lncRNA and mRNA Expression Profile of Macrophage RAW264.7 Stimulated by Antimicrobial Peptide BSN-37	12

Unraveling the Role of Functional Amyloids and Amyloid Peptides in Disease Detection	12
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study	11
Trypsin/α-Amylase Inhibitors from Capsicum chinense Seeds: Characterization and Antifungal Activity against Fungi of Agronomic Importance	11
Variable Surface Antigens of Plasmodium falciparum: Protein Families with Divergent Roles	11
Molecular Bases of Protein Antigenicity and Determinants of Immunogenicity, Anergy, and Mitogenicity	11
SNHG3/miR-330-5p/HSD11B1 Alleviates Myocardial Ischemia-reperfusion Injury by Regulating the ERK/p38 Signaling Pathway	11
A Review of Gap Junction Protein and its Potential Role in Nervous System-Related Disease	11
Protein Tyrosine Phosphatase Receptor-type Q: Structure, Activity, and Implications in Human Disease	11
Binding of l-Anilino-8-Napthalenesulfonate to Free and Coformycin-Complexed Bovine Adenosine Deaminase	10
Association between Higher Expression of Vav1 in Hepatocellular Carcinoma and Unfavourable Clinicopathological Features and Prognosis	10
Synthesis of Two Designed Hairprin Peptides on a Newly Developed 1,6-Hexanediol Diacrylate (HDODA)-Crosslinked Polystyrene Resin	10
Unveiling the Molecular Mechanism of Diosmetin and its Impact on Multifaceted Cellular Signaling Pathways	10
Gelsolin Inhibits the Proliferation of Colon Cancer Cells by Enhancing the Expression of TNFR2/CASP10 as a Death Receptor Pathway	9
Neuroprotective Effect of Dexmedetomidine Pretreatment on Sevoflurane- Initiated Neurotoxicity Via the Mir-204-5p/SOX4 Axis	9
Targeting APE1: Advancements in the Diagnosis and Treatment of Tumors	9
Guanidinium-based Integrated Peptide Dendrimers: Pioneer Nanocarrier in Cancer Therapy	9
Improved Soluble Expression in Escherichia coli and Easily Purified Recombinant Human Bone Morphogenetic 7-2 Fusion Protein	9
A Review on Recent Advancement in Expression Strategies Used in Bacillus subtilis	9
UPBEAT1-ROS-POD-PAL System under Different Xylogenesis Scenarios in Karelian Birch (Betula pendula Roth var. carelica (Mercl.) Hämet-Ahti)	9
Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta	9
Preface	8
Dexmedetomidine Alleviates Brain Ischemia/Reperfusion Injury by Regulating Metastasis-associated Lung Adenocarcinoma Transcript 1/MicroRNA-140-5p/ Nuclear Factor Erythroid-derived 2-like 2 Axis	8
Neuropeptide Network of Polycystic Ovary Syndrome – A Review	8
Structural and Functional Analysis of Urease Accessory Protein E from Vancomycin-Resistance Staphylococcus aureus MU50 Strain	7
Screening of MMP-2 Inhibiting Phytoconstituents for the Development of Newer Pancreatic Cancer Treatment Modalities	7
Methods of PARP-1 Determination and its Importance in Living Organisms	7
Insights into Coronavirus Papain-like Protease Structure, Function and Inhibitors	7
Meclofenoxate Inhibits Aggregation of Alpha-synuclein in vitro	7
Thermodynamics of the Association of Aminoglycoside Antibiotics with Human Angiogenin	7
Wogonin Restrains the Malignant Progression of Lung Cancer Through Modulating MMP1 and PI3K/AKT Signaling Pathway	7
Cold-Induced RNA-Binding Protein and RNA-Binding Motif Protein 3: Two RNA Molecular Chaperones Closely Related to Reproductive Development and Reproductive System Diseases	7
Lessons Learnt and the Way Forward for Drug Development Against Isocitrate Lyase from Mycobacterium tuberculosis	7
Preparation of IgE Antibody and Distribution of IgE+ Secretory Cells in the Palatine Tonsil of Bactrian Camel	7
Identifying the Role of Individual Seal IAPP Amino Acids in Inhibiting the Aggregation of Human IAPP	7
Regulatory Mechanism of lncRNA CTBP1-AS2 in Nasopharyngeal Carcinoma Cell Proliferation and Apoptosis via the miR-140-5p/BMP2 Axis	7
Knockdown of Programmed Death 1 Inhibited Progression of Papillary Thyroid Carcinoma in Mice	7
Modified Levels of Renin Angiotensin Related Components in the Frontal Cortex and Hippocampus were Associated with Neuroinflammation and Lower Neuroprotective Effects of NGF During Acute Hepatic Encep	7
P53-induced GAP-43 Upregulation in Primary Cortical Neurons of Rats	7
Interaction of the Seed Lectin from Parkia Platycephala (Mimosoideae) with Carbohydrates and Complex Glycans	6
Applications of CRISPR Cas-9 in Ovarian Cancer Research	6
Feasibility of Domain Segmentation of B19V VP1u Using Intein Technology for Structural Studies	6
Development of a Peptide-Based Multiepitope Vaccine from the SARS-CoV-2 Spike Protein for Targeted Immune Response Against COVID-19	6
Design of Artificial C-Peptides as Potential Anti-HIV-1 Inhibitors Based on 6-HB Formation Mechanism	6
Antimicrobial Peptides: An Overview of their Structure, Function and Mechanism of Action	6
Combining Network Pharmacology, Molecular Docking and Preliminary Experiments to Explore the Mechanism of Action of FZKA Formula on Non-small Cell Lung Cancer	6
Unidentified N-glycans by N-glycosidase A were Identified by Nglycosidase F under Denaturing Conditions in Plant Glycoprotein	6
Characterization of a Novel Thermostable 7α-Hydroxysteroid Dehydrogenase	6
Comparison of Adjuvant Effects of Montanide ISA-720 and Heat Shock Protein 27 in Increasing Immunostimulatory Properties of HIV-1 Nef-Vif Fusion Protein Construct	6
The Agonistic Activity of the Human Epidermal Growth Factor is Reduced by the D46G Substitution	6
Proteomic Analysis of Glucose-Induced Cardiac Myoblasts and the Potential Role of mir-92b-5p in Regulating Sarcomere Proteins Under a Hyperglycemic Environment	6

The LL-37 Antimicrobial Peptide as a Treatment for Systematic Infection of Acinetobacter baumannii in a Mouse Model	6
Purification, Crystallization, and Preliminary X-ray Diffraction Studies on Hemoglobin from the Angora Goat (Capra Aegagrus Hircus)	6
A Functional Human Glycogen Debranching Enzyme Encoded by a Synthetic Gene: Its Implications for Glycogen Storage Disease Type III Management	6
Expression and Purification of His-Tagged Variants of Human Hepatitis A Virus 3C Protease	6
Design, Synthesis and DNA-Binding Activities of GCN4 Peptide Dimer Studied by Circular Dichroism Spectroscopy	5
Design, Expression, and Purification of a Fusion Enzyme Containing Terminal Deoxynucleotidyl Transferase from B. bovis and DNA-Binding Proteins from E. coli	5
Circ_0008768 Suppresses the Pancreatic Cancer Progression via miR-330- 3p/PTEN Axis	5
Estrogen Sulfotransferase SULT1E1 Expression Levels and Regulated Factors in Malignant Tumours	5
Disruption of Staphylococcus aureus Biofilms with Purified Moringa oleifera Leaf Extract Protein	5
The Roles of Ciliary Neurotrophic Factor - from Neuronutrition to Energy Metabolism	5
Proteome-Wide Acetylome Profiling Suggests Extensive Aspirin-Driven Remodeling of Networks Relevant to THP-1 Macrophage Differentiation	5
Natural Amphibian-Derived Host Defense Peptides: Peptide Immunomodulators with Potential Therapeutic Value	5
Unlocking the Keratinolytic Potential of Brevibacillus agri Derived Keratinase: A Molecular Characterization Study	5
Exploring the Potential Long-term Impact of SARS-CoV-2 on Protein Misfolding and Amyloid-related Conditions	5
Analysis of the Interaction of UBE2Q1 with B4GALT1 and P53: Experimental and Molecular Modeling Study	5
Biocompatible Excipients from Microalgae: Advancing Protein and Peptide Therapeutics through Sustainable Formulation Strategies	5
Some Minor Characteristics of Spectrophotometric Determination of Antioxidant System and Phenolic Metabolism Enzyme Activity in Wood Plant Tissues of Pinus sylvestris L.	5
Advances in Polymeric Drug Delivery Systems: From Biodegradability to Nanocarrier Technologies	5
Precision Enzyme: Targeted Drug Discovery in Neurodegenerative Disorders	5
Cyclopeptide-based Anti-liver Cancer Agents: A Mini-review	5
Optimizing Sleep in Athletes: The Potential of α-Lactalbumin in Nutrition Intervention	5
Biochemical Aspects of the Spiral Grain Formation in Scots Pine (Pinus Sylvestris L.) Wood. Some Differences and Similarities with Biochemical Indicators of Abnormal Xylogenesis in Karelian Birch (Bet	5
Expression, Purification, and Evaluation of Antibody Responses and Antibody-Immunogen Complex Simulation of a Designed Multi-Epitope Vaccine against SARS-COV-2	5
MicroRNA-605-3p Inhibited the Growth and Chemoresistance of Osteosarcoma Cells via Negatively Modulating RAF1	5
Production of Soluble Murine TRAILs in Escherichia coli with Zn2+ Supplementation	5
Concentration-mediated Folding and Unfolding of Collagen Triple Helix	5
In Silico Analysis of Natural Plant-Derived Cyclotides with Antifungal Activity against Pathogenic Fungi	5
Participation of CWINV and SUS Genes in Sucrose Utilization in the Disruption of Cambium Derivatives Differentiation of Silver Birch	5
Targeting Autoimmunity in Myasthenia Gravis: From Conventional to Novel Therapeutic Approaches	4
Structure of Cadmiull}-Substituted Phospholipase A2 from Agkistrodon halys Pallas at 2.8A Resolution	4
Corrigendum to: Investigation of the Expression and Regulation of SCG5 in the Context of the Chromogranin-Secretogranin Family in Malignant Tumors	4
F18 Promiscuous Epitope of Acr1 Protein of Mycobacterium tuberculosis Induces the Secretion of IL-10 and Tregs but Not IL-6	4
Structural Properties of Rat Intestinal Fatty Acid-Binding Protein with its Dynamics: Insights into Intrinsic Disorder	4
First Display of Haloalkane Dehalogenase LinB on the Surface of Bacillus subtilis Spore	4
Antimicrobial Activity of a Defensin-Rich Fraction from Capsicum chinense Fruits: Insights for Biotechnological Applications against Fungal Infections	4
The Role of TGFBR3 in the Development of Lung Cancer	4
Study on the Analgesic Activity of Peptide from Conus achates	4
Circ_0006789 Promotes the Progression of Hepatocellular Carcinoma Cells via Modulating miR-1324 and SOX12	4
Synthesis, Anticancer Activity, Docking Calculations and Hydrolytic Stability Studies of Bioconjugates of Monofluorenated Analogue of BIM- 23052	4
Effect of Bromelain on Chronic Unpredictable Stress-induced Behavioral, Biochemical, and Monoamine Changes in Wistar Albino Rat Model of Depression	4
Hsa_circ_0000437 Inhibits the Development of Endometrial Carcinoma through miR-626/CDKN1B Axis	4
The Function and Modification of Human Defensin 5	4
Exploring the Cell Wall and Secretory Proteins of Mycobacterium leprae as Biomarkers	4
Antioxidant Responses are Crucial for Defense against Misfolded Human Z-Type α1-Antitrypsin	4
Plant-derived Cyclotides in Immunomodulation and their Therapeutic Potential	4
The Features of Shared Genes among Transcriptomes Probed in Atopic Dermatitis, Psoriasis, and Inflammatory Acne: S100A9 Selection as the Target Gene	4
Recombinant Proteins: Evolution to their Therapeutic Potential	4
SGSM2 in Uveal Melanoma: Implications for Survival, Immune Infiltration, and Drug Sensitivity	3
Zika Virus NS2B-NS3 Protease: Quantum Chemical Properties Insights into Designing Inhibitory Peptides	3
Role of Fibrinogen in Type-2 Diabetes Mellitus with Diabetic Neuropathy and its Preliminary Mechanism	3
Sequence Analysis and Biochemical Characteristics of Two Non-specific Lipid Transfer Proteins from Tartary Buckwheat Seeds	3
Corrigendum to: Neuropeptide Network of Polycystic Ovary Syndrome – A Review	3
Characterization of a Novel Protease Inhibitor from the Edible MushroomAgaricus bisporus	3
Essential Role of Non-Conserved α4-His 178 in Stabilizing the α4-α5 Hairpin and Biotoxicity of the Cry4Aa Mosquitocidal Protein	3
Expression and Functional Characterization of a Novel NAD(H)- dependent 3α-HSDH	3
Acknowledgement to Reviewers	3
Role of BLACAT1 in IL-1β-Induced Human Articular Chondrocyte Apoptosis and Extracellular Matrix Degradation via the miR-149-5p/ HMGCR Axis	3
Peptide Extract from Apricot Kernels Mitigates Damage in Human Aortic Endothelial Cells Induced by Polystyrene Microplastics through the Inhibition of the NLRP3 Signaling Pathway	3
Bioactive Peptides: Production Strategies, Biological Activities, and Emerging Therapeutic Applications	3
Amphibian-Derived Antimicrobial Peptides: Essential Components of Innate Immunity and Potential Leads for New Antibiotic Development	3
Tribute to Prof. Ben M. Dunn: A Remarkable Biochemist and Editor-in-Chief of Protein & Peptide Letters and Current Protein & Peptide Science	3
Molecular Machinery of the Triad Holin, Endolysin, and Spanin: Key Players Orchestrating Bacteriophage-Induced Cell Lysis and their Therapeutic Applications	3
Purification and Partial Characterization of 5-Oxo-L-Prolinase from Pig Kidney	3
Protein Engineering, a Robust Tool to Engineer Novel Functions in Protein	3
Expression, Purification, and Preliminary Characterization of Putative Protein Tyrosine Phosphatase Oca1	3
The Multifunction of TRIM26: From Immune Regulation to Oncology	3
Recombinant Expression of L-methioninase from Brevibacterium linens and Evaluation of its Anticarcinogenic Properties against MiaPaCa-2 Cells	3
Interleukin 6 Antagonists in Severe COVID-19 Disease: Cardiovascular and Respiratory Outcomes	3
Advances in Research on Protein Arginine Methyltransferase 2: Functions and Diseases	3
miR-584-5p Regulates MSMO1 to Modulate the AKT/PI3K Pathway and Inhibit Breast Cancer Progression	3
Self-Assembled KLD-12/SDF-1 Polypeptide Promotes Differentiation and Migration of BMSCs via the Wnt/β-catenin Signaling Pathways	3
Polyvinyl Alcohol can Stabilize FITC Conjugated Recombinant Annexin V for Apoptotic Cells Detection	3
Protein and Peptide Therapeutics: Stability Challenges, Regulatory Demands, and Innovative Formulation Solutions for Enhanced Clinical Effectiveness	3
A Review on the Potential Role of Humanin Peptide and its Analogs in the Regulation of Autophagy Pathways for Therapeutic Application in Metabolic Disorders	3
Unveiling the Potential Role of Hesperetin and Emodin as a Combination Therapy to Inhibit the Pancreatic Cancer Progression against the C-Met Gene	3
A Mini-review on Potentials Proteins/Peptides Applied for Serodiagnosis of Human Monkeypox Infection and Future Trends	3
Manganese-independent Reverse Transcriptase Activity of Tth DNA Polymerase with Two Amino Acid Substitutions	3
Physiological and Pathological Roles of NTSR2 in Several Organs and Diseases (Review)	3
Heterologous Expression and Function of Cholesterol Oxidase: A Review	2
Characterization of Heat-labile Uracil-DNA Glycosylase from Oncorhynchus mykiss and its Application for Carry-over Contamination Control in RT-qPCR	2

Reviewing the Context of Molecular Modeling to Enhance the Application of Machine Learning Technologies for Safer Bioinformatics	2
Brain Related Gut Peptides – A Review	2
Investigating In silico and In vitro Therapeutic Potential of Diosmetin as the Anti-Parkinson Agent	2
MicroRNA3650 Promotes Gastric Cancer Proliferation and Migration through the PTEN/PI3K-AKT-mTOR and Hippo Pathways	2
Margatoxin Peptide: Preparation and the Potential Use for Biological Applications in Cancer and Neurological Disorders	2
Exploring Potential Biomarkers of Early Thymoma based on Serum Proteomics	2
The Present State and Impact of AI-Driven Computational Tools for Predicting Plant Protein Structures	2
Comparing the Soluble Form of Recombinant Human Insulin-like Growth Factor-1 (rhIGF-1) in Escherichia coli Using Thioredoxin as Fused and Co-expressed Protein	2
Prokaryotic Expression and Affinity Purification of DDX3 Protein	2
Cell-Free Expression of HPV16 Minor Capsid Protein L2 and Its Interaction with S100A10	2
CircPSMC3 Inhibits Colorectal Cancer Cell Growth and Migration by Controlling miR-31-5p/YAP/β-Catenin	2
Evaluation of the Cardioprotective Potential of Syzygium aromaticum in High-Glucose and Trimethylamine-N-Oxide-Induced In-Vitro Diabetic Cardiomyopathy	2
STAM-binding Protein-like 1 Promotes Growth and Migration of Colorectal Cancer by NF-κB Pathway	2
Understanding the Molecular Basis for Enhanced Glutenase Activity of Actinidin using Structural Bioinformatics	2
Antiviral Peptides Derived from Plants: Their Designs and Functions	2
Ultrasonication Induced Alterations in Physicochemical and Functional Properties of Myosin	2
A Conserved Tryptophan (Trp10) at the Hydrophobic Core Modulates the Stability and Inhibitory Activity of Potato I Type Inhibitors	2
Evaluation of Cytotoxicity and Antimicrobial Activity of Experimental Composites Containing Chitosan-Silver Oxide Particles Against Two Main Pathogenic Bacteria in Periodontal Disease	2
Long Non-coding RNA LINC00473 Promotes Breast Cancer Progression via miR-424-5p/CCNE1 Pathway	2
The GA-Hecate Peptide inhibits the ZIKV Replicative Cycle in Different Steps and can Inhibit the Flavivirus NS2B-NS3 Protease after Cell Infection	2
miR-490-3p Alleviates Cardiomyocyte Injury via Targeting FOXO1	2
Corrigendum to: A Preliminary Study on the Antibacterial Activity of the Secretion of the Levantine Water Frog, Pelophylax bedriagae (Camerano, 1882) (Anura:Ranidae)	2
The Interaction between miRNAs and 14-3-3ζ Protein in Different Diseases	2
Calcium and Sodium-mediated Dynamic Assembly of Intermediate Filament-like Protein FilP	2
Challenges and Solutions in the Recombinant Expression of Membrane Proteins	2
Investigations on the Biological Activity of Allium sativum Agglutinin (ASA) Isolated from Garlic	2
Recent Advances in Bioactive Peptides as Functional Food for Health Promotions and Medicinal Applications	2
FN1 Promotes Thyroid Carcinoma Cell Proliferation and Metastasis by Activating the NF-Κb Pathway	2
Production and Functional Characterization of a Novel Mannanase from Alteromonadaceae Bacterium Bs31	2
Enhancing Tissue Factor Production: The Role of N-Glycosylation and ERAD Pathway Modulation	2
Carboxyl Terminus of HOATZ is Intrinsically Disordered and Interacts with Heat Shock Protein A Families	2
Pharmacokinetics of Novel Oral Cyclic Peptide	2