Cancer Gene Therapy

Article	Citations
Reducing the risks of nuclear war—the role of health professionals	113
Small extracellular vesicle TGF-β in cancer progression and immune evasion	104
P38 kinase in gastrointestinal cancers	92
Circ-GSK3B up-regulates GSK3B to suppress the progression of lung adenocarcinoma	88
Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X	85
Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance	77
Platelet activation: a barrier to effective antitumor immunity	67
Adeno-associated virus-delivered alpha synuclein inhibits bladder cancer growth via the p53/p21 signaling pathway	66
Correction to: Identification of a five genes prognosis signature for triple-negative breast cancer using multi-omics methods and bioinformatics analysis	62
Defining treatment-resistant brain cancer: Genetic screening to identify oncogene-driven immunomodulation and therapy resistance	57
ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapy	53
Correction to: FOXO3-induced lncRNA LOC554202 contributes to hepatocellular carcinoma progression via the miR-485-5p/BSG axis	50
Pan-cancer oncogenic properties and therapeutic potential of SF3B4	49
Ending nuclear weapons, before they end us	45
Long noncoding RNA EPCART regulates translation through PI3K/AKT/mTOR pathway and PDCD4 in prostate cancer	43
Targeting TLK2 inhibits the progression of gastric cancer by reprogramming amino acid metabolism through the mTOR/ASNS axis	39
Unveiling the role of the extracellular matrix in the osteosarcoma tumor microenvironment through integrated transcriptomics and experimental validation	39
Role of non-coding RNAs in neuroblastoma	39
Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity	38
Silencing of RND3/RHOE inhibits the growth of human hepatocellular carcinoma and is associated with reversible senescence	36
Viral vectors and extracellular vesicles: innate delivery systems utilized in CRISPR/Cas-mediated cancer therapy	36
PDPN contributes to constructing immunosuppressive microenvironment in IDH wildtype glioma	33
CircPKN2 promotes ferroptosis in bladder cancer by promoting the ubiquitination of Stearoyl-CoA Desaturase 1	33
TNFRSF19 promotes endoplasmic reticulum stress-induced paraptosis via the activation of the MAPK pathway in triple-negative breast cancer cells	33
SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells	33

Self-replicating messenger RNA based cancer immunotherapy	32
Pathophysiological role of ion channels and transporters in HER2-positive breast cancer	31
Exploring RNA biology in pseudomyxoma peritonei uncovers splicing dysregulation as a novel, targetable molecular vulnerability	28
circXRCC5 foster gastric cancer growth and metastasis by the HNRNPC/circXRCC5/miR-655-3p/RREB1/UBA2 positive feedback loop	27
Correction to: Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c	27
Bacillus Calmette-Guerin induces CD8+ T cell infiltration and suppresses tumor progression in microsatellite stable colorectal cancer by downregulating ARID1A	27
CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages	27
LncRNA CALML3-AS1 modulated by m6A modification induces BTNL9 methylation to drive non-small-cell lung cancer progression	26
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication	26
Real-world outcomes of Adjuvant De Gramont versus Xelox chemotherapy in reSected gasTric cancER: a propensity score-matched analysis (ASTER study)	25
Targeted inactivation of EWSR1 : : FLI1 gene in Ewing sarcoma via CRISPR/Cas9 driven by an Ewing-specific GGAA promoter	25
Single-cell atlas reveals the immunosuppressive microenvironment and Treg cells landscapes in recurrent Glioblastoma	25
The target atlas for antibody-drug conjugates across solid cancers	24
BCL-xL dependency in chromophobe renal cell carcinoma	24
Evaluation of the stability and intratumoral delivery of foreign transgenes encoded by an oncolytic Foamy Virus vector	24
Aberrant DNA methylation impacts HOX genes expression in bone marrow mesenchymal stromal cells of myelodysplastic syndromes and de novo acute myeloid leukemia	23
m6A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small-cell lung cancer	23
Editorial Expression of Concern: p73β-expressing recombinant adenovirus: a potential anticancer agent	22
Editorial Expression of Concern: E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cells	22
Retraction Note: Overexpressed transient receptor potential vanilloid 1 (TRPV1) in lung adenocarcinoma harbours a new opportunity for therapeutic targeting	21
Manipulating the tumour immune microenvironment by N6-methyladenosine RNA modification	21
Suppression of FOXO1 activity by SIRT1-mediated deacetylation weakening the intratumoral androgen autocrine function in glioblastoma	20
A conditionally replicative adenovirus vector containing the synNotch receptor gene for the treatment of muscle-invasive bladder cancer	20
SMAD4-armed oncolytic adenovirus therapy potentiates the chemotherapy effects in NSCLC through suppression of the Wnt/β-catenin pathway	20
Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas	20
NRF2-SOX4 complex regulates PSPH in hepatocellular carcinoma and modulates M2 macrophage differentiation	20
m6A-modified circABCC4 promotes stemness and metastasis of prostate cancer by recruiting IGF2BP2 to increase stability of CCAR1	19
AAV-mediated combination gene therapy of inducible Caspase 9 and miR-199a-5p is therapeutic in hepatocellular carcinoma	19
Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway	19
LOXL1-AS1 inhibits JAK2 ubiquitination and promotes cholangiocarcinoma progression through JAK2/STAT3 signaling	19
Circular RNA RHBDD1 regulates tumorigenicity and ferroptosis in colorectal cancer by mediating the ELAVL1/SCD mRNA interaction	18
Biodistribution and toxicity evaluation of oncolytic adenovirus Adf35(OGN) in Syrian hamster and mouse	18
EZH1/2 as targets for cancer therapy	18
Diving into the dark kinome: lessons learned from LMTK3	18
CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process	18
BETA prime: a first-in-man phase 1 study of AdAPT-001, an armed oncolytic adenovirus for solid tumors	18
Tumor-derived ARHGAP35 mutations enhance the Gα13-Rho signaling axis in human endometrial cancer	17
A guardian turned rogue: TP53 promoter translocations rewire stress responses to oncogenic effectors in osteosarcoma	17
Glimmers of hope for targeting oncogenic KRAS-G12D	17
Hidden patterns of gene expression provide prognostic insight for colorectal cancer	17
IER3: exploring its dual function as an oncogene and tumor suppressor	17
p53-regulated lncRNAs in cancers: from proliferation and metastasis to therapy	17
Reversible downregulation of MYC in a spheroid model of metastatic epithelial ovarian cancer	17
RETRACTED ARTICLE: Overexpressed transient receptor potential vanilloid 1 (TRPV1) in lung adenocarcinoma harbours a new opportunity for therapeutic targeting	17
Intraperitoneal administration of adeno-associated virus encoding microRNA-29b for the treatment of peritoneal metastasis	17
Chimeric Ad5/35 oncolytic adenovirus overcome preexisting neutralizing antibodies and enhance tumor targeting efficiency	16
Blocking tri-methylguanosine synthase 1 (TGS1) stops anchorage-independent growth of canine sarcomas	16
Structural regulation of PLK1 activity: implications for cell cycle function and drug discovery	16
HIF-1α/IL-8 axis in hypoxic macrophages promotes esophageal cancer progression by enhancing PD-L1 expression	16
Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function	16

Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia	16
Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway	16
Extracellular vesicles released by glioma cells are decorated by Annexin A2 allowing for cellular uptake via heparan sulfate	16
METTL3 promotes the malignancy of non-small cell lung cancer by N6-methyladenosine modifying SFRP2	16
ECT2 promotes malignant phenotypes through the activation of the AKT/mTOR pathway and cisplatin resistance in cervical cancer	16
Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice	15
WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer	15
METTL3-mediated N6-methyladenosine modification of DUSP5 mRNA promotes gallbladder-cancer progression	15
NrCAM secreted by endometrial stromal cells enhances the progestin sensitivity of endometrial cancer cells through epigenetic modulation of PRB	15
CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR	15
CRISPR-Cas gene knockouts to optimize engineered T cells for cancer immunotherapy	15
Challenges and progress toward tumor-targeted therapy by systemic delivery of polymer-complexed oncolytic adenoviruses	15
Utilizing nullomers in cell-free RNA for early cancer detection	15
SOCS3 inhibiting JAK-STAT pathway enhances oncolytic adenovirus efficacy by potentiating viral replication and T-cell activation	15
SPP1+ TAM subpopulations in tumor microenvironment promote intravasation and metastasis of head and neck squamous cell carcinoma	15
Therapeutic potential of synthetic microRNA mimics based on the miR-15/107 consensus sequence	15
MBD1 protects replication fork stability by recruiting PARP1 and controlling transcription-replication conflicts	14
Correction to: Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway	14
Gastrointestinal infections and gastrointestinal haemorrhage are underestimated but serious adverse events in chimeric antigen receptor T-cell recipients: A real-world study	14
HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer	14
RevCAR-expressing immune effector cells for targeting of Fn14-positive glioblastoma	14
STAT5a and SH2B3 novel mutations display malignancy roles in a triple-negative primary myelofibrosis patient	14
Correction to: Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression	14
FOXM1 promotes neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor progression in a NUF2-dependent manner	14
Correction: Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway	14
Long noncoding RNA LINC00173 induces radioresistance in nasopharyngeal carcinoma via inhibiting CHK2/P53 pathway	13
TSPAN1 inhibits metastasis of nasopharyngeal carcinoma via suppressing NF-kB signaling	13
An alternative fully human anti-BCMA CAR-T shows response for relapsed or refractory multiple myeloma with anti-BCMA CAR-T exposures previously	13
GPR107: A key driver of breast cancer invasion and metastasis through collagen IV modulation	13
GLIPR1 promotes proliferation, metastasis and 5-fluorouracil resistance in hepatocellular carcinoma by activating the PI3K/PDK1/ROCK1 pathway	13
Identification of lineage-specific epigenetic regulators FOXA1 and GRHL2 through chromatin accessibility profiling in breast cancer cell lines	13
The long-term effectiveness and mechanism of oncolytic virotherapy combined with anti-PD-L1 antibody in colorectal cancer patient	13
Detection of (pre)cancerous colorectal lesions in Lynch syndrome patients by microsatellite instability liquid biopsy	13
Centromere protein F promotes progression of hepatocellular carcinoma through ERK and cell cycle-associated pathways	13
Global characterization of megakaryocytes in bone marrow, peripheral blood, and cord blood by single-cell RNA sequencing	13
MALNC: a new mutant NPM1/IDH2R140 and PML-RARA-associated lncRNA with impact on AML cell proliferation, maturation and drug response	13
Integrating system biology and intratumor gene therapy by trans-complementing the appropriate co-stimulatory molecule as payload in oncolytic herpes virus	13
Somatic copy number alteration predicts clinical benefit of lung adenocarcinoma patients treated with cytokine-induced killer plus chemotherapy	12
Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer	12
Clonal dynamics limits detection of selection in tumour xenograft CRISPR/Cas9 screens	12
Regional infusion of a class C TLR9 agonist enhances liver tumor microenvironment reprogramming and MDSC reduction to improve responsiveness to systemic checkpoint inhibition	12
Correction: microRNA-let-7e in serum-derived exosomes inhibits the metastasis of non-small-cell lung cancer in a SUV39H2/LSD1/CDH1-dependent manner	12
Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against non-small cell lung cancer	12
Estrogen receptor status heterogeneity in breast cancer tumor: role in response to endocrine treatment	12
A critical ETV4/Twist1/Vimentin axis in Ha-RAS-induced aggressive breast cancer	12
Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells	12
Activating NRF2E79Q mutation alters the differentiation of human non-small cell lung cancer	12
Engineered L-asparaginase variants with enhanced therapeutic properties to improve treatment of childhood acute lymphatic leukemia	11
Correction: Hedyotis diffusae Herba-Andrographis Herba inhibits the cellular proliferation of nasopharyngeal carcinoma and triggers DNA damage through activation of p53 and p21	11
Integrated multidimensional bioinformatics analysis of the molecular mechanisms of ulcerative colitis-associated colorectal cancer and MMP1 as a potential therapeutic target	11
GAS5 attenuates the malignant progression of glioma stem-like cells by promoting E-cadherin	11
m6A-modified circFOXK2 targets GLUT1 to accelerate oral squamous cell carcinoma aerobic glycolysis	11
A novel intranasal peptide vaccine inhibits non-small cell lung cancer with KRAS mutation	11
Retraction Note: microRNA-133a exerts tumor suppressive role in oral squamous cell carcinoma through the Notch signaling pathway via downregulation of CTBP2	11
Microbiota in tumors: new factor influencing cancer development	11
Anti-angiogenesis and anti-immunosuppression gene therapy through targeting COUP-TFII in an in situ glioblastoma mouse model	11
Anti-leukemia effects of omipalisib in acute myeloid leukemia: inhibition of PI3K/AKT/mTOR signaling and suppression of mitochondrial biogenesis	11
Lipid-related FABP5 activation of tumor-associated monocytes fosters immune privilege via PD-L1 expression on Treg cells in hepatocellular carcinoma	11
Editorial Expression of Concern: Herpes simplex virus thymidine kinase/ganciclovir–induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells	11
Olfactomedin 4 produces dysplasia but suppresses metastasis of colon cancer	11
Suicide gene strategies applied in ovarian cancer studies	11
Therapeutic targeting of the tryptophan-kynurenine-aryl hydrocarbon receptor pathway with apigenin in MED12-mutant leiomyoma cells	11
Oleuropein regulates ubiquitination-mediated Mcl-1 turnover and exhibits antitumor activity	10
Redefining bioactive small molecules from microbial metabolites as revolutionary anticancer agents	10
Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy	10
RUNX1A isoform is overexpressed in acute myeloid leukemia and is associated with FLT3 internal tandem duplications	10
Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion	10
New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene	10
Correction to: ERCC6L that is up-regulated in high grade of renal cell carcinoma enhances cell viability in vitro and promotes tumor growth in vivo potentially through modulating MAPK signalling pathw	10
The dual role of GPX4 in breast cancer: mechanisms of therapeutic resistance and potential for novel targeted therapies	10
Atypical phosphatase DUSP11 inhibition promotes nc886 expression and potentiates gemcitabine-mediated cell death through NF-kB modulation	10
ERRα coordinates actin and focal adhesion dynamics	10
GTF2E2 downregulated by miR-340-5p inhibits the malignant progression of glioblastoma	10
Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent m	10
Identification of a novel prognostic ADME-related signature associated with tumor immunity for aiding therapy in head and neck squamous cell carcinoma	10
Cleavage and polyadenylation machinery as a novel targetable vulnerability for human cancer	10
Long non-coding RNAs and signaling networks in non-small cell lung cancer: mechanistic insights into tumor pathogenesis	10
Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C	9
Improving the cytotoxic response of tumor-infiltrating lymphocytes towards advanced stage ovarian cancer with an oncolytic adenovirus expressing a human vIL-2 cytokine	9
Unveiling mitochondrial and ribosomal gene deregulation and tumor microenvironment dynamics in acute myeloid leukemia	9

Pigment epithelium-derived factor, an anti-VEGF factor, delays ovarian cancer progression by alleviating polarization of tumor-associated macrophages	9
Retraction Note: Targeting KDM1B-dependent miR-215-AR-AGR2-axis promotes sensitivity to enzalutamide-resistant prostate cancer	9
Decellularized normal and cancer tissues as tools for cancer research	9
Retraction Note: circ_001504 promotes the development of renal cell carcinoma by sponging microRNA-149 to increase NUCB2	9
3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis	9
Has_circ_ASH1L acts as a sponge for miR-1254 to promote the malignant progression of cervical cancer by targeting CD36	9
LncSNHGs: new targets in osteosarcoma	9
Dicer deletion in hepatocytes promotes macrophages M1 polarization through dysregulated miR-192-3p/IGF2 in non-alcoholic steatohepatitis and hepatocellular carcinoma	9
Cancer-derived exosomal miR-375 targets DIP2C and promotes osteoblastic metastasis and prostate cancer progression by regulating the Wnt signaling pathway	9
Hsa_circ_0013561 promotes epithelial-mesenchymal transition and tumor progression by regulating ANXA2 via miR-23b-3p in ovarian cancer	9
Mitochondrial Fus1/Tusc2 and cellular Ca2+ homeostasis: tumor suppressor, anti-inflammatory and anti-aging implications	9
CILP is a potential pan-cancer marker: combined silico study and in vitro analyses	9
Predicting colorectal cancer risk in FAP patients using patient-specific organoids	9
Membrane linked RNA glycosylation as new trend to envision epi-transcriptome epoch	9
IGH repertoire analysis at scale: deciphering the complexity of B cell infiltration and migration in esophageal squamous cell carcinoma	9
FBXO22 promotes HCC angiogenesis and metastasis via RPS5/AKT/HIF-1α/VEGF-A signaling axis	9
Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT	9
Characterization of tertiary lymphoid structure identifies competitive binding of CD40 and STING with TRAF2 driving IRF4-mediated B cell activation in esophageal squamous cell carcinoma	9
Abemaciclib impairs glioblastoma sphere formation by targeting the GSK3β-mediated transcriptional regulation of CD44 and TCF7L2	9
Correction: PARD6A promotes lung adenocarcinoma cell proliferation and invasion through Serpina3	8
Reductive cell death: the other side of the coin	8
APOE deficiency triggers anti-tumour activity of macrophages in liver cancer	8
BAIAP2L2 promotes the malignancy of hepatocellular carcinoma via GABPB1-mediated reactive oxygen species imbalance	8
SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front	8
Targeting CREB-binding protein (CBP) abrogates colorectal cancer stemness through epigenetic regulation of C-MYC	8
DR1 activates histone gene expression to maintain pancreatic cancer cell survival through the ATAC complex	8
Targeting MTPN sensitizes pancreatic cancer of wild-type BRCA1/2 to Cisplatin-based chemotherapy	8
Exploring metabolic reprogramming in esophageal cancer: the role of key enzymes in glucose, amino acid, and nucleotide pathways and targeted therapies	8
Correction: Silencing of long non-coding RNA LINC01270 inhibits esophageal cancer progression and enhances chemosensitivity to 5-fluorouracil by mediating GSTP1methylation	8
METTL3 facilitates colorectal cancer growth through altering the abundance of intestinal Akkermansia muciniphila	8
CCR3 blockage elicits polyploidization associated with the signatures of epithelial-mesenchymal transition in carcinoma cell lines	8
SMARCB1-driven EGFR-GLI1 epigenetic alterations in lung cancer progression and therapy are differentially modulated by MEOX2 and GLI-1	8
Therapeutic applications of local injection of hsa-miR-634 into canine spontaneous malignant melanoma tumors	8
Respective roles of Pik3ca mutations and cyproterone acetate impregnation in mouse meningioma tumorigenesis	8
Recent advances in the role of circRNA in cisplatin resistance in tumors	8
Description and optimization of a multiplex bead-based flow cytometry method (MBFCM) to characterize extracellular vesicles in serum samples from patients with hematological malignancies	8
Cancer-associated fibroblast exosomes promote prostate cancer metastasis through miR-500a-3p/FBXW7/HSF1 axis under hypoxic microenvironment	7
Therapeutic efficacy of the novel SHP2 degrader SHP2-D26, alone or in combination, against lung cancer is associated with modulation of p70S6K/S6, Bim and Mcl-1	7
Alternative splicing events in tumor immune infiltration in renal clear cell carcinomas	7
YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma	7
Caveolin-1 knockout mitigates breast cancer metastasis to the lungs via integrin α3 dysregulation in 4T1-induced syngeneic breast cancer model	7
Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification	7
Intrinsic S phase checkpoint enforced by an antiproliferative oncosuppressor cytokine	7
Inhibition of myeloid PD-L1 suppresses osteoclastogenesis and cancer bone metastasis	7
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells	7
The splicing factor SF3B1 confers ferroptosis resistance and promotes lung adenocarcinoma progression via upregulation of SLC7A11	7
Bacterial nanoparticles as a potent and safe alternative to BCG for bladder cancer immunotherapy	7
Role of MARK2 in the nervous system and cancer	7
Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness	7
ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner	7
Blocked metabotropic glutamate receptor 5 enhances chemosensitivity in hepatocellular carcinoma and attenuates chemotoxicity in the normal liver by regulating DNA damage	7
ATPase copper transporting beta contributes to cisplatin resistance as a regulatory factor of extracellular vesicles in head and neck squamous cell carcinoma	7
Research progress and application of single-cell sequencing in head and neck malignant tumors	7
Correction to: Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells	7
UGT1A7 altered HER2-positive breast cancer response to trastuzumab by affecting epithelial-to-mesenchymal transition: A potential biomarker to identify patients resistant to trastuzumab treatment	7
Using RNA-seq for detecting MRD in multiple myeloma: high sensitivity and prognostic value	7
Next generation self-replicating RNA vectors for vaccines and immunotherapies	7
SIX3 function in cancer: progression and comprehensive analysis	7
Immuno-regulatory malignant B cells contribute to Chronic Lymphocytic Leukemia progression	7
Baicalein inhibits cell proliferation and induces apoptosis in brain glioma cells by downregulating the LGR4-EGFR pathway	7
NF-κB-activated oncogene inhibition strategy for cancer gene therapy	7
Oncolytic HSV1 targets different growth phases of breast cancer leptomeningeal metastases	7
Identification of an immune gene-associated prognostic signature in patients with bladder cancer	7
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma	7
Long non-coding RNA PRSS23-AS1 as ceRNA promotes breast cancer progression by regulating EMT via miR-3176 /YBX1 axis	7
LncRNA SNHG5 promotes the proliferation and cancer stem cell-like properties of HCC by regulating UPF1 and Wnt-signaling pathway	6
Retraction Note: Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C4	6
TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence	6
Disulfidptosis in cancer: from redox stress to therapeutic strategy	6
Histone 3 lysine 9 acetylation-specific reprogramming regulates esophageal squamous cell carcinoma progression and metastasis	6
Retraction Note: Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway	6
Phosphoglycerate mutase 1 promotes breast cancer progression through inducing immunosuppressive M2 macrophages	6
Patient-derived tumor models: a suitable tool for preclinical studies on esophageal cancer	6
Genetic trajectory and clonal evolution of multiple primary lung cancer with lymph node metastasis	6
Emerging roles of prohibitins in cancer: an update	6
HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma	6
Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell malignancy	6
Tumor-promoting properties of karyopherin β1 in melanoma by stabilizing Ras-GTPase-activating protein SH3 domain-binding protein 1	6
Targeting GNAQ/11 through PKC inhibition in uveal melanoma	6
Transcription factor YY1 mediates self-renewal of glioblastoma stem cells through regulation of the SENP1/METTL3/MYC axis	6
The pleiotropic nature of NONO, a master regulator of essential biological pathways in cancers	6
Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer	6
Promoting the therapeutic potential of interleukin-7 (IL-7) by expression in viral vectors	6
Overcoming biophysical barriers with innovative therapeutic delivery approaches	6
SPRTN is involved in hepatocellular carcinoma development through the ER stress response	6
β3-adrenergic receptor on tumor-infiltrating lymphocytes sustains IFN-γ-dependent PD-L1 expression and impairs anti-tumor immunity in neuroblastoma	6
LINC00665 activating Wnt3a/β-catenin signaling by bond with YBX1 promotes gastric cancer proliferation and metastasis	6
The role of LncRNA-MANCR induced by HIF-1α drive the malignant progression of pancreatic cancer by targeting miRNA-494/SIRT1 signaling axis under hypoxic conditions	6
c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis	6
miR-451a was selectively sorted into exosomes and promoted the progression of esophageal squamous cell carcinoma through CAB39	6
The effects of intracellular and exosomal ncRNAs on cancer progression	6
CEACAM6 facilitates gastric cancer progression through upregulating SLC27A2	6
High CAR intensity of expression confers enhanced antitumor effect against lymphoma without functional exhaustion	6
Therapeutic activity of retroviral replicating vector-mediated gene therapy in combination with anti-PD-1 antibody in a murine pancreatic cancer model	6
Novel treatment paradigms for metastatic uveal melanoma	5