Cancer Gene Therapy

Papers
(The median citation count of Cancer Gene Therapy is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Reducing the risks of nuclear war—the role of health professionals116
Homeostatic cytokines tune naivety and stemness of cord blood-derived transgenic T cells93
Correction to: Identification of a five genes prognosis signature for triple-negative breast cancer using multi-omics methods and bioinformatics analysis73
Correction: UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P5370
Circ-GSK3B up-regulates GSK3B to suppress the progression of lung adenocarcinoma66
ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapy62
Adeno-associated virus-delivered alpha synuclein inhibits bladder cancer growth via the p53/p21 signaling pathway53
Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X51
Small extracellular vesicle TGF-β in cancer progression and immune evasion49
P38 kinase in gastrointestinal cancers46
Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance45
Targeting TLK2 inhibits the progression of gastric cancer by reprogramming amino acid metabolism through the mTOR/ASNS axis45
TNFRSF19 promotes endoplasmic reticulum stress-induced paraptosis via the activation of the MAPK pathway in triple-negative breast cancer cells43
Long noncoding RNA EPCART regulates translation through PI3K/AKT/mTOR pathway and PDCD4 in prostate cancer43
CircPKN2 promotes ferroptosis in bladder cancer by promoting the ubiquitination of Stearoyl-CoA Desaturase 140
Correction to: FOXO3-induced lncRNA LOC554202 contributes to hepatocellular carcinoma progression via the miR-485-5p/BSG axis34
Role of non-coding RNAs in neuroblastoma33
Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity32
PDPN contributes to constructing immunosuppressive microenvironment in IDH wildtype glioma32
Silencing of RND3/RHOE inhibits the growth of human hepatocellular carcinoma and is associated with reversible senescence31
SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells30
Viral vectors and extracellular vesicles: innate delivery systems utilized in CRISPR/Cas-mediated cancer therapy30
Self-replicating messenger RNA based cancer immunotherapy30
The target atlas for antibody-drug conjugates across solid cancers27
Oncolytic adenoviruses synergistically enhance anti-PD-L1 and anti-CTLA-4 immunotherapy by modulating the tumour microenvironment in a 4T1 orthotopic mouse model26
Pathophysiological role of ion channels and transporters in HER2-positive breast cancer26
Combination of ZEN-3694 with CDK4/6 inhibitors reverses acquired resistance to CDK4/6 inhibitors in ER-positive breast cancer26
Targeted inactivation of EWSR1 : : FLI1 gene in Ewing sarcoma via CRISPR/Cas9 driven by an Ewing-specific GGAA promoter26
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication25
Correction: Inhibition of host Ogr1 enhances effector CD8+ T-cell function by modulating acidic microenvironment25
Enhanced antitumor immune response in melanoma tumor model by anti-PD-1 small interference RNA encapsulated in nanoliposomes25
Correction to: Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c25
Single-cell atlas reveals the immunosuppressive microenvironment and Treg cells landscapes in recurrent Glioblastoma24
circXRCC5 foster gastric cancer growth and metastasis by the HNRNPC/circXRCC5/miR-655-3p/RREB1/UBA2 positive feedback loop24
Aberrant DNA methylation impacts HOX genes expression in bone marrow mesenchymal stromal cells of myelodysplastic syndromes and de novo acute myeloid leukemia24
CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages24
Evaluation of the stability and intratumoral delivery of foreign transgenes encoded by an oncolytic Foamy Virus vector23
LncRNA CALML3-AS1 modulated by m6A modification induces BTNL9 methylation to drive non-small-cell lung cancer progression22
m6A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small-cell lung cancer22
Editorial Expression of Concern: E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cells21
Editorial Expression of Concern: p73β-expressing recombinant adenovirus: a potential anticancer agent21
Exploring RNA biology in pseudomyxoma peritonei uncovers splicing dysregulation as a novel, targetable molecular vulnerability21
Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas21
Retraction Note: Overexpressed transient receptor potential vanilloid 1 (TRPV1) in lung adenocarcinoma harbours a new opportunity for therapeutic targeting20
BETA prime: a first-in-man phase 1 study of AdAPT-001, an armed oncolytic adenovirus for solid tumors20
CF33-hNIS-antiPDL1 virus primes pancreatic ductal adenocarcinoma for enhanced anti-PD-L1 therapy19
Suppression of FOXO1 activity by SIRT1-mediated deacetylation weakening the intratumoral androgen autocrine function in glioblastoma19
AAV-mediated combination gene therapy of inducible Caspase 9 and miR-199a-5p is therapeutic in hepatocellular carcinoma19
A conditionally replicative adenovirus vector containing the synNotch receptor gene for the treatment of muscle-invasive bladder cancer19
Manipulating the tumour immune microenvironment by N6-methyladenosine RNA modification19
EZH1/2 as targets for cancer therapy18
Diving into the dark kinome: lessons learned from LMTK318
LOXL1-AS1 inhibits JAK2 ubiquitination and promotes cholangiocarcinoma progression through JAK2/STAT3 signaling17
m6A-modified circABCC4 promotes stemness and metastasis of prostate cancer by recruiting IGF2BP2 to increase stability of CCAR117
Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway17
Circular RNA RHBDD1 regulates tumorigenicity and ferroptosis in colorectal cancer by mediating the ELAVL1/SCD mRNA interaction16
Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function16
CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process16
Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway16
Tumor-derived ARHGAP35 mutations enhance the Gα13-Rho signaling axis in human endometrial cancer15
METTL3 promotes the malignancy of non-small cell lung cancer by N6-methyladenosine modifying SFRP215
Extracellular vesicles released by glioma cells are decorated by Annexin A2 allowing for cellular uptake via heparan sulfate15
RETRACTED ARTICLE: Overexpressed transient receptor potential vanilloid 1 (TRPV1) in lung adenocarcinoma harbours a new opportunity for therapeutic targeting15
Reversible downregulation of MYC in a spheroid model of metastatic epithelial ovarian cancer14
IER3: exploring its dual function as an oncogene and tumor suppressor14
Biodistribution and toxicity evaluation of oncolytic adenovirus Adf35(OGN) in Syrian hamster and mouse14
Hidden patterns of gene expression provide prognostic insight for colorectal cancer14
Chimeric Ad5/35 oncolytic adenovirus overcome preexisting neutralizing antibodies and enhance tumor targeting efficiency14
A guardian turned rogue: TP53 promoter translocations rewire stress responses to oncogenic effectors in osteosarcoma14
Downregulation of TMEM220 promotes tumor progression in Hepatocellular Carcinoma14
ECT2 promotes malignant phenotypes through the activation of the AKT/mTOR pathway and cisplatin resistance in cervical cancer14
p53-regulated lncRNAs in cancers: from proliferation and metastasis to therapy14
Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice13
WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer13
Correction to: Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression13
CRISPR-Cas gene knockouts to optimize engineered T cells for cancer immunotherapy13
SPP1+ TAM subpopulations in tumor microenvironment promote intravasation and metastasis of head and neck squamous cell carcinoma13
Glimmers of hope for targeting oncogenic KRAS-G12D13
CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR13
SOCS3 inhibiting JAK-STAT pathway enhances oncolytic adenovirus efficacy by potentiating viral replication and T-cell activation13
METTL3-mediated N6-methyladenosine modification of DUSP5 mRNA promotes gallbladder-cancer progression13
Utilizing nullomers in cell-free RNA for early cancer detection13
MiR-181c sensitizes ovarian cancer cells to paclitaxel by targeting GRP78 through the PI3K/Akt pathway13
Tumor suppressor immune gene therapy to reverse immunotherapy resistance13
Blocking tri-methylguanosine synthase 1 (TGS1) stops anchorage-independent growth of canine sarcomas13
Intraperitoneal administration of adeno-associated virus encoding microRNA-29b for the treatment of peritoneal metastasis13
Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia13
Therapeutic potential of synthetic microRNA mimics based on the miR-15/107 consensus sequence13
Challenges and progress toward tumor-targeted therapy by systemic delivery of polymer-complexed oncolytic adenoviruses13
NrCAM secreted by endometrial stromal cells enhances the progestin sensitivity of endometrial cancer cells through epigenetic modulation of PRB13
HIF-1α/IL-8 axis in hypoxic macrophages promotes esophageal cancer progression by enhancing PD-L1 expression13
Global characterization of megakaryocytes in bone marrow, peripheral blood, and cord blood by single-cell RNA sequencing12
RevCAR-expressing immune effector cells for targeting of Fn14-positive glioblastoma12
An alternative fully human anti-BCMA CAR-T shows response for relapsed or refractory multiple myeloma with anti-BCMA CAR-T exposures previously12
HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer12
Integrating system biology and intratumor gene therapy by trans-complementing the appropriate co-stimulatory molecule as payload in oncolytic herpes virus12
Centromere protein F promotes progression of hepatocellular carcinoma through ERK and cell cycle-associated pathways12
TSPAN1 inhibits metastasis of nasopharyngeal carcinoma via suppressing NF-kB signaling12
Correction: Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway12
MBD1 protects replication fork stability by recruiting PARP1 and controlling transcription-replication conflicts12
The long-term effectiveness and mechanism of oncolytic virotherapy combined with anti-PD-L1 antibody in colorectal cancer patient12
Gastrointestinal infections and gastrointestinal haemorrhage are underestimated but serious adverse events in chimeric antigen receptor T-cell recipients: A real-world study12
STAT5a and SH2B3 novel mutations display malignancy roles in a triple-negative primary myelofibrosis patient12
DRAIC promotes growth of breast cancer by sponging miR-432-5p to upregulate SLBP12
Correction to: Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway12
Detection of (pre)cancerous colorectal lesions in Lynch syndrome patients by microsatellite instability liquid biopsy12
FOXM1 promotes neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor progression in a NUF2-dependent manner12
Somatic copy number alteration predicts clinical benefit of lung adenocarcinoma patients treated with cytokine-induced killer plus chemotherapy11
Identification of lineage-specific epigenetic regulators FOXA1 and GRHL2 through chromatin accessibility profiling in breast cancer cell lines11
Clonal dynamics limits detection of selection in tumour xenograft CRISPR/Cas9 screens11
RETRACTED ARTICLE: Long non-coding RNA DIO3OS binds to microRNA-130b to restore radiosensitivity in esophageal squamous cell carcinoma by upregulating PAX911
Long noncoding RNA LINC00173 induces radioresistance in nasopharyngeal carcinoma via inhibiting CHK2/P53 pathway11
A novel intranasal peptide vaccine inhibits non-small cell lung cancer with KRAS mutation11
A critical ETV4/Twist1/Vimentin axis in Ha-RAS-induced aggressive breast cancer11
Cabozantinib promotes erythroid differentiation in K562 erythroleukemia cells through global changes in gene expression and JNK activation11
GLIPR1 promotes proliferation, metastasis and 5-fluorouracil resistance in hepatocellular carcinoma by activating the PI3K/PDK1/ROCK1 pathway11
Correction: microRNA-let-7e in serum-derived exosomes inhibits the metastasis of non-small-cell lung cancer in a SUV39H2/LSD1/CDH1-dependent manner11
Estrogen receptor status heterogeneity in breast cancer tumor: role in response to endocrine treatment11
Regional infusion of a class C TLR9 agonist enhances liver tumor microenvironment reprogramming and MDSC reduction to improve responsiveness to systemic checkpoint inhibition11
Microbiota in tumors: new factor influencing cancer development10
Olfactomedin 4 produces dysplasia but suppresses metastasis of colon cancer10
Anti-angiogenesis and anti-immunosuppression gene therapy through targeting COUP-TFII in an in situ glioblastoma mouse model10
Systems analysis identifies endothelin 1 axis blockade for enhancing the anti-tumor effect of multikinase inhibitor10
Redefining bioactive small molecules from microbial metabolites as revolutionary anticancer agents10
Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells10
Correction: Hedyotis diffusae Herba-Andrographis Herba inhibits the cellular proliferation of nasopharyngeal carcinoma and triggers DNA damage through activation of p53 and p2110
Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent m10
Therapeutic targeting of the tryptophan-kynurenine-aryl hydrocarbon receptor pathway with apigenin in MED12-mutant leiomyoma cells10
Editorial Expression of Concern: Herpes simplex virus thymidine kinase/ganciclovir–induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells10
Retraction Note: microRNA-133a exerts tumor suppressive role in oral squamous cell carcinoma through the Notch signaling pathway via downregulation of CTBP210
Lipid-related FABP5 activation of tumor-associated monocytes fosters immune privilege via PD-L1 expression on Treg cells in hepatocellular carcinoma10
m6A-modified circFOXK2 targets GLUT1 to accelerate oral squamous cell carcinoma aerobic glycolysis10
GAS5 attenuates the malignant progression of glioma stem-like cells by promoting E-cadherin10
Anti-leukemia effects of omipalisib in acute myeloid leukemia: inhibition of PI3K/AKT/mTOR signaling and suppression of mitochondrial biogenesis10
LncRNA MAGI2-AS3 inhibits tumor progression and angiogenesis by regulating ACY1 via interacting with transcription factor HEY1 in clear cell renal cell carcinoma9
Correction: Synergistic tumor inhibition of colon cancer cells by nitazoxanide and obeticholic acid, a farnesoid X receptor ligand9
GTF2E2 downregulated by miR-340-5p inhibits the malignant progression of glioblastoma9
CILP is a potential pan-cancer marker: combined silico study and in vitro analyses9
Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C9
Correction to: ERCC6L that is up-regulated in high grade of renal cell carcinoma enhances cell viability in vitro and promotes tumor growth in vivo potentially through modulating MAPK signalling pathw9
Cleavage and polyadenylation machinery as a novel targetable vulnerability for human cancer9
Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion9
IGH repertoire analysis at scale: deciphering the complexity of B cell infiltration and migration in esophageal squamous cell carcinoma9
Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy9
Suicide gene strategies applied in ovarian cancer studies9
Identification of a novel prognostic ADME-related signature associated with tumor immunity for aiding therapy in head and neck squamous cell carcinoma9
Atypical phosphatase DUSP11 inhibition promotes nc886 expression and potentiates gemcitabine-mediated cell death through NF-kB modulation9
Retraction Note: circ_001504 promotes the development of renal cell carcinoma by sponging microRNA-149 to increase NUCB29
Unveiling mitochondrial and ribosomal gene deregulation and tumor microenvironment dynamics in acute myeloid leukemia9
Mitochondrial Fus1/Tusc2 and cellular Ca2+ homeostasis: tumor suppressor, anti-inflammatory and anti-aging implications8
3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis8
Dicer deletion in hepatocytes promotes macrophages M1 polarization through dysregulated miR-192-3p/IGF2 in non-alcoholic steatohepatitis and hepatocellular carcinoma8
Improving the cytotoxic response of tumor-infiltrating lymphocytes towards advanced stage ovarian cancer with an oncolytic adenovirus expressing a human vIL-2 cytokine8
ERRα coordinates actin and focal adhesion dynamics8
Has_circ_ASH1L acts as a sponge for miR-1254 to promote the malignant progression of cervical cancer by targeting CD368
Decellularized normal and cancer tissues as tools for cancer research8
Fatty acid β-oxidation promotes breast cancer stemness and metastasis via the miRNA-328-3p-CPT1A pathway8
FBXO22 promotes HCC angiogenesis and metastasis via RPS5/AKT/HIF-1α/VEGF-A signaling axis8
Membrane linked RNA glycosylation as new trend to envision epi-transcriptome epoch8
Cancer-derived exosomal miR-375 targets DIP2C and promotes osteoblastic metastasis and prostate cancer progression by regulating the Wnt signaling pathway7
Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT7
Description and optimization of a multiplex bead-based flow cytometry method (MBFCM) to characterize extracellular vesicles in serum samples from patients with hematological malignancies7
Targeting CREB-binding protein (CBP) abrogates colorectal cancer stemness through epigenetic regulation of C-MYC7
Exploring metabolic reprogramming in esophageal cancer: the role of key enzymes in glucose, amino acid, and nucleotide pathways and targeted therapies7
Hsa_circ_0013561 promotes epithelial-mesenchymal transition and tumor progression by regulating ANXA2 via miR-23b-3p in ovarian cancer7
Non-homologous dsODN increases the mutagenic effects of CRISPR-Cas9 to disrupt oncogene E7 in HPV positive cells7
Correction: PARD6A promotes lung adenocarcinoma cell proliferation and invasion through Serpina37
Retraction Note: Targeting KDM1B-dependent miR-215-AR-AGR2-axis promotes sensitivity to enzalutamide-resistant prostate cancer7
Inhibition of host Ogr1 enhances effector CD8+ T-cell function by modulating acidic microenvironment7
Recent advances in the role of circRNA in cisplatin resistance in tumors7
Caveolin-1 knockout mitigates breast cancer metastasis to the lungs via integrin α3 dysregulation in 4T1-induced syngeneic breast cancer model7
SMARCB1-driven EGFR-GLI1 epigenetic alterations in lung cancer progression and therapy are differentially modulated by MEOX2 and GLI-17
CCR3 blockage elicits polyploidization associated with the signatures of epithelial-mesenchymal transition in carcinoma cell lines7
SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front7
CXCR4 and anti-BCMA CAR co-modified natural killer cells suppress multiple myeloma progression in a xenograft mouse model7
Reductive cell death: the other side of the coin7
ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner7
Pigment epithelium-derived factor, an anti-VEGF factor, delays ovarian cancer progression by alleviating polarization of tumor-associated macrophages7
Sunitinib and Axitinib increase secretion and glycolytic activity of small extracellular vesicles in renal cell carcinoma7
Cancer-associated fibroblast exosomes promote prostate cancer metastasis through miR-500a-3p/FBXW7/HSF1 axis under hypoxic microenvironment6
SIX3 function in cancer: progression and comprehensive analysis6
Correction: Silencing of long non-coding RNA LINC01270 inhibits esophageal cancer progression and enhances chemosensitivity to 5-fluorouracil by mediating GSTP1methylation6
Immuno-regulatory malignant B cells contribute to Chronic Lymphocytic Leukemia progression6
Intrinsic S phase checkpoint enforced by an antiproliferative oncosuppressor cytokine6
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma6
Inhibition of myeloid PD-L1 suppresses osteoclastogenesis and cancer bone metastasis6
TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence6
BAIAP2L2 promotes the malignancy of hepatocellular carcinoma via GABPB1-mediated reactive oxygen species imbalance6
Alternative splicing events in tumor immune infiltration in renal clear cell carcinomas6
Therapeutic efficacy of the novel SHP2 degrader SHP2-D26, alone or in combination, against lung cancer is associated with modulation of p70S6K/S6, Bim and Mcl-16
Respective roles of Pik3ca mutations and cyproterone acetate impregnation in mouse meningioma tumorigenesis6
Therapeutic applications of local injection of hsa-miR-634 into canine spontaneous malignant melanoma tumors6
UGT1A7 altered HER2-positive breast cancer response to trastuzumab by affecting epithelial-to-mesenchymal transition: A potential biomarker to identify patients resistant to trastuzumab treatment6
Baicalein inhibits cell proliferation and induces apoptosis in brain glioma cells by downregulating the LGR4-EGFR pathway6
Identification of an immune gene-associated prognostic signature in patients with bladder cancer6
Targeting GNAQ/11 through PKC inhibition in uveal melanoma6
NF-κB-activated oncogene inhibition strategy for cancer gene therapy6
YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma6
Retraction Note: Upregulating microRNA-498 inhibits gastric cancer proliferation invasion and chemoresistance through inverse interaction of Bmi16
Role of MARK2 in the nervous system and cancer6
Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness6
Research progress and application of single-cell sequencing in head and neck malignant tumors6
The splicing factor SF3B1 confers ferroptosis resistance and promotes lung adenocarcinoma progression via upregulation of SLC7A116
Correction to: Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells6
Oncolytic HSV1 targets different growth phases of breast cancer leptomeningeal metastases6
Blocked metabotropic glutamate receptor 5 enhances chemosensitivity in hepatocellular carcinoma and attenuates chemotoxicity in the normal liver by regulating DNA damage6
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells6
Next generation self-replicating RNA vectors for vaccines and immunotherapies6
The pleiotropic nature of NONO, a master regulator of essential biological pathways in cancers5
Histone 3 lysine 9 acetylation-specific reprogramming regulates esophageal squamous cell carcinoma progression and metastasis5
c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis5
Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell malignancy5
Retraction Note: Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway5
Therapeutic activity of retroviral replicating vector-mediated gene therapy in combination with anti-PD-1 antibody in a murine pancreatic cancer model5
Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer5
Emerging roles of prohibitins in cancer: an update5
HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma5
SPRTN is involved in hepatocellular carcinoma development through the ER stress response5
Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification5
The role of LncRNA-MANCR induced by HIF-1α drive the malignant progression of pancreatic cancer by targeting miRNA-494/SIRT1 signaling axis under hypoxic conditions5
β3-adrenergic receptor on tumor-infiltrating lymphocytes sustains IFN-γ-dependent PD-L1 expression and impairs anti-tumor immunity in neuroblastoma5
LINC00665 activating Wnt3a/β-catenin signaling by bond with YBX1 promotes gastric cancer proliferation and metastasis5
Heparanase interacting BCLAF1 to promote the development and drug resistance of ICC through the PERK/eIF2α pathway5
The effects of intracellular and exosomal ncRNAs on cancer progression5
miR-451a was selectively sorted into exosomes and promoted the progression of esophageal squamous cell carcinoma through CAB395
LncRNA SNHG5 promotes the proliferation and cancer stem cell-like properties of HCC by regulating UPF1 and Wnt-signaling pathway5
Reovirus mutant jin-3 exhibits lytic and immune-stimulatory effects in preclinical human prostate cancer models5
Tumor-promoting properties of karyopherin β1 in melanoma by stabilizing Ras-GTPase-activating protein SH3 domain-binding protein 15
Transcription factor YY1 mediates self-renewal of glioblastoma stem cells through regulation of the SENP1/METTL3/MYC axis5
Small molecule-induced epigenomic reprogramming of APL blasts leading to antiviral-like response and c-MYC downregulation5
FCH domain only 1 (FCHo1), a potential new biomarker for lung cancer5
High CAR intensity of expression confers enhanced antitumor effect against lymphoma without functional exhaustion5
Genetic trajectory and clonal evolution of multiple primary lung cancer with lymph node metastasis5
The function of brother of the regulator of imprinted sites in cancer development5
Correction: SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front4
ALKBH5-mediated m6A regulates the alternative splicing events of SRSF10 in ovarian cancer4
Correction: H3.3-G34W in giant cell tumor of bone functionally aligns with the exon choice repressor hnRNPA1L24
Inhibition of orthotopic castration-resistant prostate cancer growth and metastasis in mice by JC VLPs carrying a suicide gene driven by the PSA promoter4
Retraction Note: BET inhibitor I-BET151 sensitizes GBM cells to temozolomide via PUMA induction4
LncRNA LINC00649 recruits TAF15 and enhances MAPK6 expression to promote the development of lung squamous cell carcinoma via activating MAPK signaling pathway4
Deciphering the role of post-translational modifications in fanconi anemia proteins and their influence on tumorigenesis4
Understanding, diagnosing, and treating pancreatic cancer from the perspective of telomeres and telomerase4
Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma4
Mesenchymal stem cells as therapeutic vehicles for glioma4
GRIN2A mutation is a novel indicator of stratifying beneficiaries of immune checkpoint inhibitors in multiple cancers4
The LIN28B/TGF-β/TGFBI feedback loop promotes cell migration and tumour initiation potential in cholangiocarcinoma4
Switching anti-EGFR antibody re-sensitizes head and neck cancer patient following acquired resistance to cetuximab4
Dickkopf-1 (DKK1) drives growth and metastases in castration-resistant prostate cancer4
The antitumor peptide M1-20 induced the degradation of CDK1 through CUL4-DDB1-DCAF1-involved ubiquitination4
Regulation of tumor metabolism by post translational modifications on metabolic enzymes4
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