OOIR: Observatory of International Research

Papers

(The H4-Index of Cancer Gene Therapy is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Reducing the risks of nuclear war—the role of health professionals	113
Small extracellular vesicle TGF-β in cancer progression and immune evasion	104
P38 kinase in gastrointestinal cancers	92
Circ-GSK3B up-regulates GSK3B to suppress the progression of lung adenocarcinoma	88
Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X	85
Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance	77
Platelet activation: a barrier to effective antitumor immunity	67
Adeno-associated virus-delivered alpha synuclein inhibits bladder cancer growth via the p53/p21 signaling pathway	66
Correction to: Identification of a five genes prognosis signature for triple-negative breast cancer using multi-omics methods and bioinformatics analysis	62
Defining treatment-resistant brain cancer: Genetic screening to identify oncogene-driven immunomodulation and therapy resistance	57
ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapy	53
Correction to: FOXO3-induced lncRNA LOC554202 contributes to hepatocellular carcinoma progression via the miR-485-5p/BSG axis	50
Pan-cancer oncogenic properties and therapeutic potential of SF3B4	49
Ending nuclear weapons, before they end us	45
Long noncoding RNA EPCART regulates translation through PI3K/AKT/mTOR pathway and PDCD4 in prostate cancer	43
Unveiling the role of the extracellular matrix in the osteosarcoma tumor microenvironment through integrated transcriptomics and experimental validation	39
Role of non-coding RNAs in neuroblastoma	39
Targeting TLK2 inhibits the progression of gastric cancer by reprogramming amino acid metabolism through the mTOR/ASNS axis	39
Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity	38
Silencing of RND3/RHOE inhibits the growth of human hepatocellular carcinoma and is associated with reversible senescence	36
Viral vectors and extracellular vesicles: innate delivery systems utilized in CRISPR/Cas-mediated cancer therapy	36
TNFRSF19 promotes endoplasmic reticulum stress-induced paraptosis via the activation of the MAPK pathway in triple-negative breast cancer cells	33
SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells	33
PDPN contributes to constructing immunosuppressive microenvironment in IDH wildtype glioma	33
CircPKN2 promotes ferroptosis in bladder cancer by promoting the ubiquitination of Stearoyl-CoA Desaturase 1	33

Self-replicating messenger RNA based cancer immunotherapy	32
Pathophysiological role of ion channels and transporters in HER2-positive breast cancer	31
Exploring RNA biology in pseudomyxoma peritonei uncovers splicing dysregulation as a novel, targetable molecular vulnerability	28