Inflammopharmacology

Article	Citations
The Role and Therapeutic Potential of NF-kappa-B Pathway in Severe COVID-19 Patients	219
Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer’s disease	150
Role of vitamins and minerals as immunity boosters in COVID-19	106
COVID-19 vaccines and decreased transmission of SARS-CoV-2	103
Exosome engineering in cell therapy and drug delivery	93
COVID-19 and the role of cytokines in this disease	64
The anti-inflammatory role of SSRI and SNRI in the treatment of depression: a review of human and rodent research studies	61
Real-world effectiveness of BNT162b2 mRNA vaccine: a meta-analysis of large observational studies	57
Pathogenesis and management of traumatic brain injury (TBI): role of neuroinflammation and anti-inflammatory drugs	57
Health benefits of cyanidin-3-glucoside as a potent modulator of Nrf2-mediated oxidative stress	51
High-mobility group box 1 (HMGB1) in COVID-19: extrapolation of dangerous liaisons	49
Brief review of the mRNA vaccines COVID-19	46
A retrospective study of the efficacy of JAK inhibitors or abatacept on rheumatoid arthritis-interstitial lung disease	43
COVID-19 and corticosteroids: a narrative review	43
Neuropathophysiology of coronavirus disease 2019: neuroinflammation and blood brain barrier disruption are critical pathophysiological processes that contribute to the clinical symptoms of SARS-CoV-2	43
SIRT1 pathway in Parkinson’s disease: a faraway snapshot but so close	42
Natural compounds as safe therapeutic options for ulcerative colitis	40
Melatonin and multiple sclerosis: antioxidant, anti-inflammatory and immunomodulator mechanism of action	38
The role of AMPK-dependent pathways in cellular and molecular mechanisms of metformin: a new perspective for treatment and prevention of diseases	38
Neuroprotective effect of liraglutide in an experimental mouse model of multiple sclerosis: role of AMPK/SIRT1 signaling and NLRP3 inflammasome	37
Pirfenidone and post-Covid-19 pulmonary fibrosis: invoked again for realistic goals	36
Microglia polarization in nociplastic pain: mechanisms and perspectives	35
Dapagliflozin, an SGLT2 inhibitor, ameliorates acetic acid-induced colitis in rats by targeting NFκB/AMPK/NLRP3 axis	34
Standardised pomegranate peel extract lavage prevents postoperative peritoneal adhesion by regulating TGF-β and VEGF levels	34
Colchicine effectively attenuates inflammatory biomarker high-sensitivity C-reactive protein (hs-CRP) in patients with non-ST-segment elevation myocardial infarction: a randomised, double-blind, place	34

Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases	32
Therapeutic benefits of flavonoids against neuroinflammation: a systematic review	31
A raising dawn of pentoxifylline in management of inflammatory disorders in Covid-19	30
Nerolidol: a potential approach in rheumatoid arthritis through reduction of TNF-α, IL-1β, IL-6, NF-kB, COX-2 and antioxidant effect in CFA-induced arthritic model	30
Protective effect of (+)–catechin against lipopolysaccharide-induced inflammatory response in RAW 264.7 cells through downregulation of NF-κB and p38 MAPK	27
Neuroprotective potential of isothiocyanates in an in vitro model of neuroinflammation	27
Thioredoxin-interacting protein (TXNIP) as a target for Alzheimer’s disease: flavonoids and phenols	26
Hesperetin as an anti-SARS-CoV-2 agent can inhibit COVID-19-associated cancer progression by suppressing intracellular signaling pathways	26
Boswellic acids/Boswellia serrata extract as a potential COVID-19 therapeutic agent in the elderly	26
Potential role of lipoxin in the management of COVID-19: a narrative review	25
Cardiac inflammation and fibrosis following chemo/radiation therapy: mechanisms and therapeutic agents	25
Benzodiazepines in Alzheimer’s disease: beneficial or detrimental effects	25
Exogenous stromal cell-derived factor-1 (SDF-1) suppresses the NLRP3 inflammasome and inhibits pyroptosis in synoviocytes from osteoarthritic joints via activation of the AMPK signaling pathway	24
The role of berberine in Covid-19: potential adjunct therapy	23
Evaluation of antioxidant and anti-ulcerogenic effects of Eremurus persicus (Jaub & Spach) Boiss leaf hydroalcoholic extract on ethanol-induced gastric ulcer in rats	23
Targeting of neuroinflammation by glibenclamide in Covid-19: old weapon from arsenal	23
Advancing combination treatment with glycyrrhizin and boswellic acids for hospitalized patients with moderate COVID-19 infection: a randomized clinical trial	23
Chemical characterization and anti-arthritic appraisal of Monotheca buxifolia methanolic extract in Complete Freund’s Adjuvant-induced arthritis in Wistar rats	22
Ursolic acid and SARS-CoV-2 infection: a new horizon and perspective	22
Effects of coenzyme Q10 supplementation on inflammation, angiogenesis, and oxidative stress in breast cancer patients: a systematic review and meta-analysis of randomized controlled- trials	22
Elucidating the role of hypoxia-inducible factor in rheumatoid arthritis	21
The effect of glutamine supplementation on serum levels of some inflammatory factors, oxidative stress, and appetite in COVID-19 patients: a case–control study	21
Could the fibromyalgia syndrome be triggered or enhanced by COVID-19?	21
Dapagliflozin as an autophagic enhancer via LKB1/AMPK/SIRT1 pathway in ovariectomized/d-galactose Alzheimer’s rat model	21
Kaempferol potentiates the sensitivity of pancreatic cancer cells to erlotinib via inhibition of the PI3K/AKT signaling pathway and epidermal growth factor receptor	21
Orchestrated modulation of rheumatoid arthritis via crosstalking intracellular signaling pathways	20
Immune-related adverse events (irAEs) in ankylosing spondylitis (AS) patients treated with interleukin (IL)-17 inhibitors: a systematic review and meta-analysis	20
Lipoxin A4 regulates M1/M2 macrophage polarization via FPR2–IRF pathway	20
Tetrahydrocannabinol and cannabidiol medicines for chronic pain and mental health conditions	20
A review of the biological and pharmacological activities of mesalazine or 5-aminosalicylic acid (5-ASA): an anti-ulcer and anti-oxidant drug	20
Protective effect of andrographolide against STZ induced Alzheimer’s disease in experimental rats: possible neuromodulation and Aβ(1–42) analysis	20
Indomethacin loaded dextran stearate polymeric micelles improve adjuvant-induced arthritis in rats: design and in vivo evaluation	19
Bortezomib: a proteasome inhibitor for the treatment of autoimmune diseases	19
A story of the potential effect of non-steroidal anti-inflammatory drugs (NSAIDs) in Parkinson’s disease: beneficial or detrimental effects	19
Periplaneta americana extract ameliorates dextran sulfate sodium-induced ulcerative colitis via immunoregulatory and PI3K/AKT/NF-κB signaling pathways	19
Is sitagliptin effective for SARS-CoV-2 infection: false or true prophecy?	19
Targeting intercellular adhesion molecule-1 (ICAM-1) to reduce rhinovirus-induced acute exacerbations in chronic respiratory diseases	19
Osteopontin in autoimmune disorders: current knowledge and future perspective	19
Evaluating the mucoprotective effects of glycyrrhizic acid-loaded polymeric nanoparticles in a murine model of 5-fluorouracil-induced intestinal mucositis via suppression of inflammatory mediators and	19
SARS-CoV-2 may trigger inflammasome and pyroptosis in the central nervous system: a mechanistic view of neurotropism	19
Melatonin induces apoptosis and cell cycle arrest in cervical cancer cells via inhibition of NF-κB pathway	18
Venlafaxine demonstrated anti-arthritic activity possibly through down regulation of TNF-α, IL-6, IL-1β, and COX-2	18
Management of COVID-19-induced cytokine storm by Keap1-Nrf2 system: a review	18
Rutin ameliorates malaria pathogenesis by modulating inflammatory mechanism: an in vitro and in vivo study	18
Diapocynin neuroprotective effects in 3-nitropropionic acid Huntington’s disease model in rats: emphasis on Sirt1/Nrf2 signaling pathway	18
Pterostilbene improves CFA-induced arthritis and peripheral neuropathy through modulation of oxidative stress, inflammatory cytokines and neurotransmitters in Wistar rats	17
Advancement of nanomedicines in chronic inflammatory disorders	17
Novel anti-arthritic mechanisms of trans-cinnamaldehyde against complete Freund’s adjuvant-induced arthritis in mice: involvement of NF-кB/TNF-α and IL-6/IL-23/ IL-17 pathways in the immuno-inflammato	17
Preclinical evidence for quercetin against inflammatory bowel disease: a meta-analysis and systematic review	17
The wound healing effect of botanicals and pure natural substances used in in vivo models	16

Pharmacological evaluation of anti-arthritic potential of terpinen-4-ol using in vitro and in vivo assays	16
Selenium, selenoprotein P, and oxidative stress levels in SARS-CoV-2 patients during illness and recovery	16
Review of natural compounds for potential psoriasis treatment	16
Metformin ameliorates the status epilepticus- induced hippocampal pathology through possible mTOR modulation	16
Molecular and pathobiological involvement of fetuin-A in the pathogenesis of NAFLD	16
Anti-inflammatory potential of Empagliflozin	16
Phytochemical profiling, in vitro and in vivo anti-inflammatory, analgesic and antipyretic potential of Sesuvium sesuvioides (Fenzl) Verdc. (Aizoaceae)	16
Antioxidants: an approach for restricting oxidative stress induced neurodegeneration in Alzheimer’s disease	16
COPD lung studies of Nrf2 expression and the effects of Nrf2 activators	16
The potential therapeutic effect of statins in multiple sclerosis: beneficial or detrimental effects	15
Role of the NRG1/ErbB4 and PI3K/AKT/mTOR signaling pathways in the anti-psychotic effects of aripiprazole and sertindole in ketamine-induced schizophrenia-like behaviors in rats	15
Modulation of KIF17/NR2B crosstalk by tozasertib attenuates inflammatory pain in rats	15
Maltol ameliorates intervertebral disc degeneration through inhibiting PI3K/AKT/NF-κB pathway and regulating NLRP3 inflammasome-mediated pyroptosis	15
Phenols and terpenoids: natural products as inhibitors of NLRP3 inflammasome in cardiovascular diseases	15
Minocycline attenuates cholinergic dysfunction and neuro-inflammation-mediated cognitive impairment in scopolamine-induced Alzheimer’s rat model	15
What is really ‘Long COVID’?	15
The NLRP3 inflammasome: role in the pathobiology of chronic pain	15
Long-term use of metformin and Alzheimer’s disease: beneficial or detrimental effects	15
Omicron variant evolution on vaccines and monoclonal antibodies	14
Miconia albicans and Curcuma longa herbal medicines positively modulate joint pain, function and inflammation in patients with osteoarthritis: a clinical study	14
In vitro biological potential of the essential oil of some aromatic species used in Iranian traditional medicine	14
Exploring the role of Aquaporins (AQPs) in LPS induced systemic inflammation and the ameliorative effect of Garcinia in male Wistar rat	14
Immunomodulatory effects of umbilical mesenchymal stem cell-derived exosomes on CD4+ T cells in patients with primary Sjögren's syndrome	14
Cellular mechanisms and molecular pathways linking bitter taste receptor signalling to cardiac inflammation, oxidative stress, arrhythmia and contractile dysfunction in heart diseases	14
Nuciferine attenuates lipopolysaccharide-stimulated inflammatory responses by inhibiting p38 MAPK/ATF2 signaling pathways	14
Biosynthesis of gold nanoparticles for the treatment of osteoarthritis alone or in combination with Diacerein® in a rat model	13
Dimethyl fumarate attenuates 2-VO-induced vascular dementia via activating the Nrf2 signaling pathway in rats	13
Cancer vs. SARS-CoV-2 induced inflammation, overlapping functions, and pharmacological targeting	13
Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic	13
Role of Myeloid-derived suppressor cell (MDSC) in autoimmunity and its potential as a therapeutic target	13
New insights into geraniol’s antihemolytic, anti-inflammatory, antioxidant, and anticoagulant potentials using a combined biological and in silico screening strategy	13
Quercetin-loaded chitosan nanoparticles ameliorate adjuvant-induced arthritis in rats by regulating anti-oxidant enzymes and downregulating pro- and inflammatory cytokines	13
Methotrexate and theaflavin-3, 3′-digallate synergistically restore the balance between apoptosis and autophagy in synovial fibroblast of RA: an ex vivo approach with cultured human RA FLS	13
Escin suppresses immune cell infiltration and selectively modulates Nrf2/HO-1, TNF-α/JNK, and IL-22/STAT3 signaling pathways in concanavalin A-induced autoimmune hepatitis in mice	13
Beneficial effects of secretome derived from mesenchymal stem cells with stigmasterol to negate IL-1β-induced inflammation in-vitro using rat chondrocytes—OA management	13
Neuroprotective effect of tangeretin against chromium-induced acute brain injury in rats: targeting Nrf2 signaling pathway, inflammatory mediators, and apoptosis	13
Donepezil attenuates injury following ischaemic stroke by stimulation of neurogenesis, angiogenesis, and inhibition of inflammation and apoptosis	13
Amelioration of oxidative stress, cholinergic dysfunction, and neuroinflammation in scopolamine-induced amnesic rats fed with pomegranate seed	12
Active components from Lagotis brachystachya maintain uric acid homeostasis by inhibiting renal TLR4-NLRP3 signaling in hyperuricemic mice	12
Myeloid-derived suppressor cells (MDSCs) in brain cancer: challenges and therapeutic strategies	12
Lycopene: a therapeutic strategy against coronavirus disease 19 (COVID- 19)	12
Statins block mammalian target of rapamycin pathway: a possible novel therapeutic strategy for inflammatory, malignant and neurodegenerative diseases	12
Cell-free probiotic supernatant (CFS) treatment alleviates indomethacin-induced enterocolopathy in BALB/c mice by down-modulating inflammatory response and oxidative stress: potential alternative targ	12
The effect of Nigella sativa (black seed) on biomarkers of inflammation and oxidative stress: an updated systematic review and meta-analysis of randomized controlled trials	12
The role of adenosine receptor ligands on inflammatory pain: possible modulation of TRPV1 receptor function	12
Anti-inflammatory mechanisms of eucalyptol rich Eucalyptus globulus essential oil alone and in combination with flurbiprofen	12
Diosmetin, a novel transient receptor potential vanilloid 1 antagonist, alleviates the UVB radiation-induced skin inflammation in mice	12
The effects of apigenin administration on the inhibition of inflammatory responses and oxidative stress in the lung injury models: a systematic review and meta-analysis of preclinical evidence	12
The risk of mortality in patients with COVID-19 with pre-diagnosis use of NSAIDs: a meta-analysis	12
Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin	11
Brain insulin resistance linked Alzheimer’s and Parkinson’s disease pathology: An undying implication of epigenetic and autophagy modulation	11
Berberis lycium fruit extract and its phytoconstituents berberine and rutin mitigate collagen–CFA-induced arthritis (CIA) via improving GSK3β/STAT/Akt/MAPKs/NF-κB signaling axis mediated oxi-inflammat	11
Protective effects of curcumin and Ginkgo biloba extract combination on a new model of Alzheimer’s disease	11
The effects of berberine on inflammatory markers in Chinese patients with metabolic syndrome and related disorders: a meta‑analysis of randomized controlled trials	11
The effects of pomegranate consumption on inflammatory and oxidative stress biomarkers in adults: a systematic review and meta-analysis	11
Deubiquitylating enzymes: potential target in autoimmune diseases	11
Role of intracellular signaling pathways and their inhibitors in the treatment of inflammation	11
Shedding light on vitamin D: the shared mechanistic and pathophysiological role between hypovitaminosis D and COVID-19 risk factors and complications	11
Neuroprotective effects of roflumilast against quinolinic acid-induced rat model of Huntington’s disease through inhibition of NF-κB mediated neuroinflammatory markers and activation of cAMP/CREB/BDNF	11
Clinical efficacy of melatonin as adjunctive therapy to non-surgical treatment of periodontitis: a systematic review and meta-analysis	11
Osteoarthritis complications and the recent therapeutic approaches	11
Tumor necrosis factor alpha (TNF-α) blockage reduces acute inflammation and delayed wound healing in oral ulcer of rats	11
In vitro and in vivo assessment of the anti-inflammatory activity of olive leaf extract in rats	11
A review on curcumin colon-targeted oral drug delivery systems for the treatment of inflammatory bowel disease	11
Early response to JAK inhibitors on central sensitization and pain catastrophizing in patients with active rheumatoid arthritis	11
The effects of vitamin C on respiratory, allergic and immunological diseases: an experimental and clinical-based review	11
Anti-inflammatory and antioxidant properties of Alternanthera brasiliana improve cutaneous wound healing in rats	11
Oral administration of essential oil from Psidium glaziovianum Kiaersk leaves alleviates pain and inflammation in mice	10
Neuromodulatory effect of vardenafil on aluminium chloride/d-galactose induced Alzheimer’s disease in rats: emphasis on amyloid-beta, p-tau, PI3K/Akt/p53 pathway, endoplasmic reticulum stress, and cel	10
Long noncoding RNA intersectin 1-2 gradually declines during adalimumab treatment, and its reduction correlates with treatment efficacy in patients with ankylosing spondylitis	10
Fatigue, sleepiness and sleep quality are SARS-CoV-2 variant independent in patients with long COVID symptoms	10
The anti-angiogenesis mechanism of Geniposide on rheumatoid arthritis is related to the regulation of PTEN	10
Spermine protects aluminium chloride and iron-induced neurotoxicity in rat model of Alzheimer's disease via attenuation of tau phosphorylation, Amyloid-β (1–42) and NF-κB pathway	10
A pilot safety, tolerability and pharmacokinetic study of an oro-buccal administered cannabidiol-dominant anti-inflammatory formulation in healthy individuals: a randomized placebo-controlled single-b	10
Current jakinibs for the treatment of rheumatoid arthritis: a systematic review	10
Development and evaluation emulgel for effective management of the imiquimod-induced psoriasis	10
A cellular and molecular biology-based update for ivermectin against COVID-19: is it effective or non-effective?	10
Sarcococca saligna extract attenuates formaldehyde-induced arthritis in Wistar rats via modulation of pro-inflammatory and inflammatory biomarkers	10
NSAIDs and Kelleni’s protocol as potential early COVID-19 treatment game changer: could it be the final countdown?	10
Comparison of individual and combination treatments with naproxen, prednisolone and hydroxychloroquine to treat Complete Freund’s Adjuvant induced arthritis	10

Ibuprofen, other NSAIDs and COVID-19: a narrative review	10
Nebivolol elicits a neuroprotective effect in the cuprizone model of multiple sclerosis in mice: emphasis on M1/M2 polarization and inhibition of NLRP3 inflammasome activation	10
Anti-rheumatic activity of pseudoephedrine (a substituted phenethylamine) in complete Freund’s adjuvant-induced arthritic rats by down regulating IL-1β, IL-6 and TNF-α as well as upregulating IL-4 and	10
COVID-19 and nutriceutical therapies, especially using zinc to supplement antimicrobials	10
A randomized controlled trial assessing the safety and efficacy of palmitoylethanolamide for treating diabetic-related peripheral neuropathic pain	10
Cassia absus-mediated upregulation of IL-4, IL-10 and downregulation of IL-1β, IL-6, TNF- α, NF-κB, IFN-γ in CFA-induced arthritis model	10
Black Seed (Nigella sativa): A Favourable Alternative Therapy for Inflammatory and Immune System Disorders	9
Protective effect of methyl gallate on murine antigen-induced arthritis by inhibiting inflammatory process and bone erosion	9
Role of triggering receptor expressed on myeloid cells-1 (TREM-1) in COVID-19 and other viral pneumonias: a systematic review and meta-analysis of clinical studies	9
The effect of ramatroban on cytokine and thrombotic storms in Covid-19	9
Inhibition of STAT3 phosphorylation by colchicine regulates NLRP3 activation to alleviate sepsis-induced acute lung injury	9
Modulation of autophagy, apoptosis and oxidative stress: a clue for repurposing metformin in photoaging	9
Novel acetamide derivatives of 2-aminobenzimidazole prevent inflammatory arthritis in rats via suppression of pro-inflammatory mediators	9
Phenolic acids-rich fraction from Ficus drupacea leaves for the prevention and treatment of ethanol-induced gastric mucosal injury in rats	9
Effects of hydro-ethanolic extract of leaves of Maesa lanceolata (Mursinaceae) on acetic acid-induced ulcerative colitis in rats	9
Anti-inflammatory and anti-COVID-19 effect of a novel polyherbal formulation (Imusil) via modulating oxidative stress, inflammatory mediators and cytokine storm	9
Aromatic-turmerone ameliorates DSS-induced ulcerative colitis via modulating gut microbiota in mice	9
Silymarin constrains diacetyl-prompted oxidative stress and neuroinflammation in rats: involvements of Dyn/GDNF and MAPK signaling pathway	9
Association between metabolic associated fatty liver disease and osteoarthritis using data from the Korean national health and nutrition examination survey (KNHANES)	9
The key role of Calpain in COVID-19 as a therapeutic strategy	9
A novel pharmacological mechanism of anti-cancer drugs that induce pyroptosis	9
Repurposing monoamine oxidase inhibitors (MAOI) for the treatment of rheumatoid arthritis possibly through modulating reactive oxidative stress mediated inflammatory cytokines	9
Diosmin nanocrystal gel alleviates imiquimod-induced psoriasis in rats via modulating TLR7,8/NF-κB/micro RNA-31, AKT/mTOR/P70S6K milieu, and Tregs/Th17 balance	9
Anti-inflammatory and antioxidant activities of Gymnema Sylvestre extract rescue acute respiratory distress syndrome in rats via modulating the NF-κB/MAPK pathway	9
Recent updates on immunological, pharmacological, and alternative approaches to combat COVID-19	9
Curcumin and n-acetylcysteine cocrystal produced with supercritical solvent: characterization, solubility, and preclinical evaluation of antinociceptive and anti-inflammatory activities	9
A brief, highly selective history of acute phase proteins as indicators of infection, inflammation and injury	9
Acteoside isolated from Colebrookea oppositifolia attenuates I/R brain injury in Wistar rats via modulation of HIF-1α, NF-κB, and VEGF pathways	9
Dexmedetomidine alleviates acute lung injury by promoting Tregs differentiation via activation of AMPK/SIRT1 pathway	9
Role of neopterin as an inflammatory biomarker in congestive heart failure with insights on effect of drug therapies on its level	9
Effect of statins on the plasma/serum levels of inflammatory markers in patients with cardiovascular disease; a systematic review and meta-analysis of randomized clinical trials	9
Short-term celecoxib (celebrex) adjuvant therapy: a clinical trial study on COVID-19 patients	9
Therapeutic potential of natural products in inflammation: underlying molecular mechanisms, clinical outcomes, technological advances, and future perspectives	9
Inflawell® improves neutrophil-to-lymphocyte ratio and shortens hospitalization in patients with moderate COVID-19, in a randomized double-blind placebo-controlled clinical trial	8
Impact of curcumin on p38 MAPK: therapeutic implications	8
The association between neutrophil-to-lymphocyte ratio and disease activity in rheumatoid arthritis	8
Exploration of molecular mechanisms responsible for anti-inflammatory and anti-angiogenic attributes of methanolic extract of Viola betonicifolia	8
Long-COVID syndrome: physical–mental interplay in the spotlight	8
Cholinergic anti-inflammatory pathway and connective tissue diseases	8
The positive effect of pregnancy in rheumatoid arthritis and the use of medications for the management of rheumatoid arthritis during pregnancy	8
Beneficial role of Pistacia lentiscus aqueous extract in experimental colitis: anti-inflammatory and potential therapeutic effects	8
Synovial mesenchymal stem cell-derived exosomal microRNA-320c facilitates cartilage damage repair by targeting ADAM19-dependent Wnt signalling in osteoarthritis rats	8
Liquiritigenin, isoliquiritigenin rich extract of glycyrrhiza glabra roots attenuates inflammation in macrophages and collagen-induced arthritis in rats	8
The effects of phytochemicals and herbal bio-active compounds on tumour necrosis factor-α in overweight and obese individuals: a clinical review	8
Emerging concepts and directed therapeutics for the management of asthma: regulating the regulators	8
Dysregulation of immunity in COVID-19 and SLE	8
The crosstalk among TLR2, TLR4 and pathogenic pathways; a treasure trove for treatment of diabetic neuropathy	8
Beneficial effect of dimethyl fumarate on experimental autoimmune uveitis is dependent of pro-inflammatory markers immunomodulation	8
Polystichum braunii ameliorates airway inflammation by attenuation of inflammatory and oxidative stress biomarkers, and pulmonary edema by elevation of aquaporins in ovalbumin-induced allergic asthmat	8
Infliximab prevents systemic bone loss and suppresses tendon inflammation in a collagen-induced arthritis rat model	8
PI3K/AKT signaling activation by roflumilast ameliorates rotenone-induced Parkinson’s disease in rats	8
Pharmaco-immunomodulatory interventions for averting cytokine storm-linked disease severity in SARS-CoV-2 infection	8
Nutritional deficiencies that may predispose to long COVID	8
Colony-stimulating factor 1 receptor signaling in the central nervous system and the potential of its pharmacological inhibitors to halt the progression of neurological disorders	8
Recombinant human erythropoietin and interferon-β-1b protect against 3-nitropropionic acid-induced neurotoxicity in rats: possible role of JAK/STAT signaling pathway	8
Ameliorative effect of montelukast against STZ induced diabetic nephropathy: targeting HMGB1, TLR4, NF-κB, NLRP3 inflammasome, and autophagy pathways	8
Anti-inflammatory activity of palmitoylethanolamide ameliorates osteoarthritis induced by monosodium iodoacetate in Sprague–Dawley rats	7
Targeting inflammation and redox perturbations by lisinopril mitigates Freund’s adjuvant-induced arthritis in rats: role of JAK-2/STAT-3/RANKL axis, MMPs, and VEGF	7
Oxycodone–paracetamol tablet exhibits increased analgesic efficacy for acute postoperative pain, higher satisfaction and comparable safety profiles compared with celecoxib in patients underwent arthro	7
Metformin improves depressive-like behavior in experimental Parkinson’s disease by inducing autophagy in the substantia nigra and hippocampus	7
Regulation of Nrf2 and NF-κB activities may contribute to the anti-inflammatory mechanism of xylopic acid	7
Anti-inflammatory potential of cannabidiol (CBD) on combination of caecal slurry, LPS, and E. coli-induced systemic inflammatory response syndrome (SIRS) in Sprague Dawley Rats	7
Curcumin alleviates lipopolysaccharides-induced inflammation and apoptosis in vascular smooth muscle cells via inhibition of the NF-κB and JNK signaling pathways	7
The impact of SARS-CoV-2 treatment on the cardiovascular system: an updated review	7
Melatonin ameliorates lung cell inflammation and apoptosis caused by Klebsiella pneumoniae via AMP-activated protein kinase	7
Nirmatrelvir–remdesivir association for non-hospitalized adults with COVID-19, point of view	7
HPLC–ESI–QTOF–MS/MS profiling and therapeutic effects of Schinus terebinthifolius and Schinus molle fruits: investigation of their antioxidant, antidiabetic, anti-inflammatory and antinociceptive prop	7
Ellagic acid protects type II collagen induced arthritis in rat via diminution of IKB phosphorylation and suppression IKB-NF-kB complex activation: in vivo and in silico study	7
Clinical efficacy and safety of melatonin supplementation in multiple sclerosis: a systematic review	7
Diabetes as one of the long-term COVID-19 complications: from the potential reason of more diabetic patients’ susceptibility to COVID-19 to the possible caution of future global diabetes tsunami	7
Multisystem inflammatory syndrome in children (MIS-C): Implications for long COVID	7
Immunogenicity and safety of the CoronaVac and BNT162b2 Covid-19 vaccine in patients with inflammatory rheumatic diseases and healthy adults: comparison of different vaccines	7
Evaluation serum levels of Insulin Growth Factor-1 (IGF-1) and its association with clinical parameters in severe COVID-19	7
A perspective study of the possible impact of obeticholic acid against SARS-CoV-2 infection	7
The modulatory effects of alkaloid extracts of Cannabis sativa, Datura stramonium, Nicotiana tabacum and male Carica papaya on neurotransmitter, neurotrophic and neuroinflammatory systems linked to an	7
Taxifolin blocks monosodium urate crystal-induced gouty inflammation by regulating phagocytosis and autophagy	7
Efficiency and safety: comparison between preoperative analgesia and postoperative analgesia using non-steroidal anti-inflammatory drugs in patients receiving arthroscopic knee surgery in a multicente	7
Long COVID and possible preventive options	7
Immune Response Gene-1 [IRG1]/itaconate protect against multi-organ injury via inhibiting gasdermin D-mediated pyroptosis and inflammatory response	7
Psoriatic arthritis: review of potential biomarkers predicting response to TNF inhibitors	6
Plasma angiotensin peptides as biomarkers of rheumatoid arthritis are correlated with anti-ACE2 auto-antibodies level and disease intensity	6
MicroRNAs-mediated regulation pathways in rheumatic diseases	6
Bioactive fraction from Plumeria obtusa L. attenuates LPS-induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF-MS and molecular docking	6
Emerging trends in combination strategies with phototherapy in advanced psoriasis management	6
Ouabain inhibits p38 activation in mice neutrophils	6
Gastroprotective and anti-Helicobacter pylori potentials of essential oils from the oleoresins of Araucaria bidwillii and Araucaria heterophylla	6
A new prenylated benzoquinone from Cyathocalyx pruniferus abrogates LPS-induced inflammatory responses associated with PGE2, COX-2 and cytokines biosynthesis in human plasma	6
Association between chemosensory dysfunctions and inflammatory biomarkers in patients with SARS-CoV-2 infection: a systematic review and meta-analysis	6
Citral protects against LPS-induced endometritis by inhibiting ferroptosis through activating Nrf2 signaling pathway	6
Pollen and bee bread expressed highest anti-inflammatory activities among bee products in chronic inflammation: an experimental study with cotton pellet granuloma in rats	6
Pterostilbene reduces the progression of atopic dermatitis via modulating inflammatory and oxidative stress biomarkers in mice	6
The emerging coloprotective effect of sildenafil against ulcerative colitis in rats via exerting counterbalance between NF-κB signaling and Nrf-2/HO-1 pathway	6
Umbelliferon: a review of its pharmacology, toxicity and pharmacokinetics	6
Green-lipped (greenshell™) mussel (Perna canaliculus) extract supplementation in treatment of osteoarthritis: a systematic review	6
The effect of statin therapy in combination with ezetimibe on circulating C-reactive protein levels: a systematic review and meta-analysis of randomized controlled trials	6