Biochimica et Biophysica Acta-Molecular Basis of Disease

Article	Citations
SARS-CoV-2 spike promotes inflammation and apoptosis through autophagy by ROS-suppressed PI3K/AKT/mTOR signaling	118
Diabetic fibrosis	105
VCAM-1 as a predictor biomarker in cardiovascular disease	100
Pleiotropic effects of statins: A focus on cancer	98
Oxidative stress and mitochondrial dysfunction in early-onset and late-onset preeclampsia	98
Metabolomics, physical activity, exercise and health: A review of the current evidence	84
Role and regulation of autophagy in cancer	81
FXR in liver physiology: Multiple faces to regulate liver metabolism	79
Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort study.	70
Autophagy and EMT in cancer and metastasis: Who controls whom?	65
A perspective on the role of autophagy in cancer	64
The central role of glutathione peroxidase 4 in the regulation of ferroptosis and its implications for pro-inflammatory cytokine-mediated beta-cell death	61
Iron deposition-induced ferroptosis in alveolar type II cells promotes the development of pulmonary fibrosis	61
Pregnancy and viral infections: Mechanisms of fetal damage, diagnosis and prevention of neonatal adverse outcomes from cytomegalovirus to SARS-CoV-2 and Zika virus	60
A machine learning framework to trace tumor tissue-of-origin of 13 types of cancer based on DNA somatic mutation	56
SARS-CoV-2 infection negatively affects ovarian function in ART patients	53
PPARs in liver physiology	52
NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury	49
Endoplasmic reticulum stress-mediated mitochondrial dysfunction in aged hearts	45
Orexin-A alleviates astrocytic apoptosis and inflammation via inhibiting OX1R-mediated NF-κB and MAPK signaling pathways in cerebral ischemia/reperfusion injury	44
Protective effect of gallic acid and gallic acid-loaded Eudragit-RS 100 nanoparticles on cisplatin-induced mitochondrial dysfunction and inflammation in rat kidney	44
The role of synaptic microRNAs in Alzheimer's disease	43
MOTS-c interacts synergistically with exercise intervention to regulate PGC-1α expression, attenuate insulin resistance and enhance glucose metabolism in mice via AMPK signaling pathway	43
Berberine and Emodin abrogates breast cancer growth and facilitates apoptosis through inactivation of SIK3-induced mTOR and Akt signaling pathway	42
Excessive ROS production and enhanced autophagy contribute to myocardial injury induced by branched-chain amino acids: Roles for the AMPK-ULK1 signaling pathway and α7nAChR	40

Targeted regulation of autophagy using nanoparticles: New insight into cancer therapy	39
TEAD4 promotes tumor development in patients with lung adenocarcinoma via ERK signaling pathway	39
The xenobiotic receptors PXR and CAR in liver physiology, an update	39
Prostate cancer-derived exosomes promote osteoblast differentiation and activity through phospholipase D2	38
Membrane lipids and transporter function	38
Transcriptome analysis provides new molecular signatures in sporadic Cerebral Cavernous Malformation endothelial cells	37
Long non-coding RNA LINC00511/miR-150/MMP13 axis promotes breast cancer proliferation, migration and invasion	37
Methionine restriction alleviates high-fat diet-induced obesity: Involvement of diurnal metabolism of lipids and bile acids	36
Cancer cell metabolism: Rewiring the mitochondrial hub	36
The role of the retinoid receptor, RAR/RXR heterodimer, in liver physiology	35
Placental mitochondrial dysfunction with metabolic diseases: Therapeutic approaches	35
Donepezil provides neuroprotective effects against brain injury and Alzheimer's pathology under conditions of cardiac ischemia/reperfusion injury	33
Repositioning Ivermectin for Covid-19 treatment: Molecular mechanisms of action against SARS-CoV-2 replication	33
Dynamic placenta-on-a-chip model for fetal risk assessment of nanoparticles intended to treat pregnancy-associated diseases	31
Glucose induces metabolic reprogramming in neutrophils during type 2 diabetes to form constitutive extracellular traps and decreased responsiveness to lipopolysaccharides	30
Spinal muscular atrophy: Broad disease spectrum and sex-specific phenotypes	30
Small-cell lung cancer brain metastasis: From molecular mechanisms to diagnosis and treatment	30
Biased signaling in naturally occurring mutations of G protein-coupled receptors associated with diverse human diseases	29
Fostering mesenchymal stem cell therapy to halt cytokine storm in COVID-19	29
New drug targets for hypertension: A literature review	29
Mitochondrial dysfunction in the fetoplacental unit in gestational diabetes mellitus	29
TRIM15 promotes the invasion and metastasis of pancreatic cancer cells by mediating APOA1 ubiquitination and degradation	28
Emerging functions of the nuclear receptor LRH-1 in liver physiology and pathology	28
Amyloid aggregates exert cell toxicity causing irreversible damages in the endoplasmic reticulum	27
Nuclear receptors in liver fibrosis	27
Oxidative stress-induced apoptosis and autophagy: Balancing the contrary forces in spermatogenesis	27
Exosomes, autophagy and ER stress pathways in human diseases: Cross-regulation and therapeutic approaches	27
NLRP3 inflammasome activation in alveolar epithelial cells promotes myofibroblast differentiation of lung-resident mesenchymal stem cells during pulmonary fibrogenesis	27
Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of TBK1 to facilitate mitophagy	27
Comparison of bovine serum albumin glycation by ribose and fructose in vitro and in vivo	26
Beyond cells: The extracellular circulating 20S proteasomes	26
P-cadherin induces anoikis-resistance of matrix-detached breast cancer cells by promoting pentose phosphate pathway and decreasing oxidative stress	26
IL-22 ameliorated cardiomyocyte apoptosis in cardiac ischemia/reperfusion injury by blocking mitochondrial membrane potential decrease, inhibiting ROS and cytochrome C	26
d-2-Hydroxyglutarate is an anti-inflammatory immunometabolite that accumulates in macrophages after TLR4 activation	25
GPR65 (TDAG8) inhibits intestinal inflammation and colitis-associated colorectal cancer development in experimental mouse models	25
Amyloid-β induced membrane damage instigates tunneling nanotube-like conduits by p21-activated kinase dependent actin remodulation	25
SIRT6 controls hepatic lipogenesis by suppressing LXR, ChREBP, and SREBP1	25
Evolutionary artificial intelligence based peptide discoveries for effective Covid-19 therapeutics	24
Molecular investigation of glycated insulin-induced insulin resistance via insulin signaling and AGE-RAGE axis	24
Physical exercise and seizure activity	24
Elevated levels of MicroRNA-455-3p in the cerebrospinal fluid of Alzheimer's patients: A potential biomarker for Alzheimer's disease	24
SIRT1 and SIRT6: The role in aging-related diseases	23
HDAC6 inhibitor accelerates wound healing by inhibiting tubulin mediated IL-1β secretion in diabetic mice	23
Pentacyclic triterpene oleanolic acid protects against cardiac aging through regulation of mitophagy and mitochondrial integrity	23
Kallistatin/Serpina3c inhibits cardiac fibrosis after myocardial infarction by regulating glycolysis via Nr4a1 activation	23
Mechanisms and repair strategies for white matter degeneration in CNS injury and diseases	22
Human alveolar macrophages do not rely on glucose metabolism upon activation by lipopolysaccharide	22
Liver X receptors and liver physiology	22
Aquaporins and (in)fertility: More than just water transport	22
Circulating cell-free mitochondrial DNA levels correlate with body mass index and age	22

Phosphorylated tau targeted small-molecule PROTACs for the treatment of Alzheimer's disease and tauopathies	22
Ablation of FUNDC1-dependent mitophagy renders myocardium resistant to paraquat-induced ferroptosis and contractile dysfunction	21
Mitochondrial calcium handling and heart disease in diabetes mellitus	21
HIV in pregnancy: Mother-to-child transmission, pharmacotherapy, and toxicity	21
CXCL12 derived from CD248-expressing cancer-associated fibroblasts mediates M2-polarized macrophages to promote nonsmall cell lung cancer progression	21
Cardiac hypertrophy drives PGC-1α suppression associated with enhanced O-glycosylation	21
Long non-coding RNAs orchestrate various molecular and cellular processes by modulating epithelial-mesenchymal transition in head and neck squamous cell carcinoma	21
Three dimensions of autophagy in regulating tumor growth: cell survival/death, cell proliferation, and tumor dormancy	20
TRIM-NHL as RNA Binding Ubiquitin E3 Ligase (RBUL): Implication in development and disease pathogenesis	20
KLF2 regulates neutrophil migration by modulating CXCR1 and CXCR2 in asthma	20
Targeting the tumor microenvironment: Potential strategy for cancer therapeutics	20
Prevotella copri ameliorates cholestasis and liver fibrosis in primary sclerosing cholangitis by enhancing the FXR signalling pathway	20
Mutations in cis that affect mRNA synthesis, processing and translation	20
Epigenetic regulation of autophagy in gastrointestinal cancers	20
The interaction between brain and liver regulates lipid metabolism in the TBI pathology	20
The circadian nuclear receptor RORα negatively regulates cerebral ischemia–reperfusion injury and mediates the neuroprotective effects of melatonin	19
Nuclear factor of activated T-cells (NFAT) regulation of IL-1β-induced retinal vascular inflammation	19
GYY4137 ameliorates sepsis-induced cardiomyopathy via NLRP3 pathway	19
Metabolomic-based clinical studies and murine models for acute pancreatitis disease: A review	19
Targeting dynamin-related protein-1 as a potential therapeutic approach for mitochondrial dysfunction in Alzheimer's disease	19
Identification of novel candidate genes in heterotaxy syndrome patients with congenital heart diseases by whole exome sequencing	19
Kidney and plasma metabolomics provide insights into the molecular mechanisms of urate nephropathy in a mouse model of hyperuricemia	19
Otto Warburg: The journey towards the seminal discovery of tumor cell bioenergetic reprogramming	19
The role of autophagy in the metabolism and differentiation of stem cells	19
Mitochondrial function, dynamics and quality control in the pathophysiology of HFpEF	18
The LMTK-family of kinases: Emerging important players in cell physiology and pathogenesis	18
Targeting lactate production and efflux in prostate cancer	18
Novel epigenetic therapeutic strategies and targets in cancer	18
Resolvin-D1 attenuation of angiotensin II-induced cardiac inflammation in mice is associated with prevention of cardiac remodeling and hypertension	18
Sodium current abnormalities and deregulation of Wnt/β-catenin signaling in iPSC-derived cardiomyocytes generated from patient with arrhythmogenic cardiomyopathy harboring compound genetic variants in	18
A high salt diet induces tubular damage associated with a pro-inflammatory and pro-fibrotic response in a hypertension-independent manner	18
COVID-19 in pregnancy: What we know from the first year of the pandemic	18
The molecular mosaic of regulated cell death in the cardiovascular system	18
Metformin induced lactic acidosis impaired response of cancer cells towards paclitaxel and doxorubicin: Role of monocarboxylate transporter	18
Regulation of autophagy by bile acids and in cholestasis - CholestoPHAGY or CholeSTOPagy	18
Targeting Nrf2 for ferroptosis-based therapy: Implications for overcoming ferroptosis evasion and therapy resistance in cancer	17
Novel molecular markers of cardiovascular disease risk in type 2 diabetes mellitus	17
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin	17
βB2 W151R mutant is prone to degradation, aggregation and exposes the hydrophobic side chains in the fourth Greek Key motif	17
Translocase of the outer mitochondrial membrane complex subunit 20 (TOMM20) facilitates cancer aggressiveness and therapeutic resistance in chondrosarcoma	17
The risk of COVID-19 for pregnant women: Evidences of molecular alterations associated with preeclampsia in SARS-CoV-2 infection	17
Extracellular HMGB1 augments macrophage inflammation by facilitating the endosomal accumulation of ALD-DNA via TLR2/4-mediated endocytosis	17
Activation of CD44-Lipoprotein lipase axis in breast cancer stem cells promotes tumorigenesis	17
Blood-based DNA methylation signatures in cancer: A systematic review	17
PAX9 reactivation by inhibiting DNA methyltransferase triggers antitumor effect in oral squamous cell carcinoma	17
Exogenous ketone ester administration attenuates systemic inflammation and reduces organ damage in a lipopolysaccharide model of sepsis	16
Vesicular ATP release from hepatocytes plays a role in the progression of nonalcoholic steatohepatitis	16
Nrf2 signaling in diabetic nephropathy, cardiomyopathy and neuropathy: Therapeutic targeting, challenges and future prospective	16
Therapeutic potential of melatonin in colorectal cancer: Focus on lipid metabolism and gut microbiota	16
Hexahydrocurcumin ameliorates hypertensive and vascular remodeling in L-NAME-induced rats	16
Human amyloid beta and α-synuclein co-expression in neurons impair behavior and recapitulate features for Lewy body dementia in Caenorhabditis elegans	16
Cinnamic acid nanoparticles modulate redox signal and inflammatory response in gamma irradiated rats suffering from acute pancreatitis	16
BRAF paradox breakers PLX8394, PLX7904 are more effective against BRAFV600Ε CRC cells compared with the BRAF inhibitor PLX4720 and shown by detailed pathway analysis	16
Increase in PPARγ inhibitory phosphorylation by Fetuin—A through the activation of Ras-MEK-ERK pathway causes insulin resistance	16
Rapid diagnosis of malignant pleural mesothelioma and its discrimination from lung cancer and benign exudative effusions using blood serum	16
Inter-individual variation in CYP2A6 activity and chronic obstructive pulmonary disease in smokers: Perspectives for an early predictive marker	16
Inhibition of macrophage-derived foam cells by Adipsin attenuates progression of atherosclerosis	16
DNMT3A facilitates colorectal cancer progression via regulating DAB2IP mediated MEK/ERK activation	16
α-lipoic acid ameliorates inflammation state and oxidative stress by reducing the content of bioactive lipid derivatives in the left ventricle of rats fed a high-fat diet	16
Biological insights in the pathogenesis of hypermobile Ehlers-Danlos syndrome from proteome profiling of patients' dermal myofibroblasts	16
Harnessing the therapeutic potential of antibodies targeting connexin hemichannels	16
Pregnane X receptor (PXR) protects against cisplatin-induced acute kidney injury in mice	16
The spike protein of SARS-CoV-2 induces heme oxygenase-1: Pathophysiologic implications	16
BMAL1 modulates smooth muscle cells phenotypic switch towards fibroblast-like cells and stabilizes atherosclerotic plaques by upregulating YAP1	16
SIRT1 attenuates neuroinflammation by deacetylating HSPA4 in a mouse model of Parkinson's disease	16
c-Abl activates RIPK3 signaling in Gaucher disease	16
The heterogeneity of fibrosis and angiogenesis in endometriosis revealed by single-cell RNA-sequencing	15
Dysregulated autophagy: A key player in the pathophysiology of type 2 diabetes and its complications	15
Plasmacytoid dendritic cells promote the pathogenesis of Sjögren's syndrome	15
Homozygous missense mutation in UQCRC2 associated with severe encephalomyopathy, mitochondrial complex III assembly defect and activation of mitochondrial protein quality control	15
Molecular and pro-inflammatory aspects of COVID-19: The impact on cardiometabolic health	15
Cross-disease analysis of depression, ataxia and dystonia highlights a role for synaptic plasticity and the cerebellum in the pathophysiology of these comorbid diseases	15
S-adenosyl-L-methionine (SAMe) halts the autoimmune response in patients with primary biliary cholangitis (PBC) via antioxidant and S-glutathionylation processes in cholangiocytes	15
The zonula occludens protein family regulates the hepatic barrier system in the murine liver	15
Chemopreventive effects of vitamin D3 and its analogue, paricalcitol, in combination with 5-fluorouracil against colorectal cancer: The role of calcium signalling molecules	15
Connexins as therapeutic targets in neurological and neuropsychiatric disorders	15
A systematic review of post-translational modifications in the mitochondrial permeability transition pore complex associated with cardiac diseases	15
Inhibition of mitochondrial fission protects podocytes from albumin-induced cell damage in diabetic kidney disease	15
Identification of cell-to-cell interactions by ligand-receptor pairs in human fetal heart	14
Role of AKR1B10 and AKR1B8 in the pathogenesis of non-alcoholic steatohepatitis (NASH) in mouse	14

Intranasal insulin improves the structure–function of the brain mitochondrial ATP–sensitive Ca2+ activated potassium channel and respiratory chain activities under diabetic conditions	14
Deciphering the key mechanisms leading to alteration of lipid metabolism in Drosophila model of Huntington's disease	14
ISG15 attenuates post-translational modifications of mitofusins and congression of damaged mitochondria in Ataxia Telangiectasia cells	14
Age–related and atherosclerosis–related erythropathy in ApoE/LDLR−/− mice	14
Cationic liposome-encapsulated carotenoids as a potential treatment for fibromyalgia in an animal model	14
SLC6A14 deficiency is linked to obesity, fatty liver, and metabolic syndrome but only under conditions of a high-fat diet	14
HIF-1α/FOXO1 axis regulated autophagy is protective for β cell survival under hypoxia in human islets	14
Clusterin in Alzheimer's disease: An amyloidogenic inhibitor of amyloid formation?	14
Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathways	14
Prominent hypertrophy of perivascular adipocytes due to short-term high fat diet	14
The Human Explanted Heart Program: A translational bridge for cardiovascular medicine	14
Regulating mitochondrial metabolism by targeting pyruvate dehydrogenase with dichloroacetate, a metabolic messenger	13
Tadalafil enhances the therapeutic efficacy of BET inhibitors in hepatocellular carcinoma through activating Hippo pathway	13
Itaconate controls its own synthesis via feedback-inhibition of reverse TCA cycle activity at IDH2	13
Uterine leiomyoma as useful model to unveil morphometric and macromolecular collagen state and impairment in fibrotic diseases: An ex-vivo human study	13
An emerging role of the 5′ termini of mature tRNAs in human diseases: Current situation and prospects	13
Significance of the placental barrier in antenatal viral infections	13
HNF1α controls glucagon secretion in pancreatic α-cells through modulation of SGLT1	13
PKC epsilon as a neonatal target to correct FXS-linked AMPA receptor translocation in the hippocampus, boost PVN oxytocin expression, and normalize adult behavior in Fmr1 knockout mice	13
Activation of α7nACh receptor protects against acute pancreatitis through enhancing TFEB-regulated autophagy	13
Multi-OMICS approaches in cancer biology: New era in cancer therapy	13
Mechanobiology of solid tumors	13
Resolvin E1 attenuates doxorubicin-induced cardiac fibroblast senescence: A key role for IL-1β	13
Reduction in endoplasmic reticulum stress activates beige adipocytes differentiation and alleviates high fat diet-induced metabolic phenotypes	13
IL2RA+VSIG4+ tumor-associated macrophage is a key subpopulation of the immunosuppressive microenvironment in anaplastic thyroid cancer	13
Butyrate ameliorated ferroptosis in ulcerative colitis through modulating Nrf2/GPX4 signal pathway and improving intestinal barrier	13
The genetics of Autosomal Recessive Polycystic Kidney Disease (ARPKD)	13
Simvastatin inhibits hepatic stellate cells activation by regulating the ferroptosis signaling pathway	13
Metastatic outgrowth via the two-way interplay of autophagy and metabolism	13
Non-coding RNA crosstalk with nuclear receptors in liver disease	12
Central role of the placenta during viral infection: Immuno-competences and miRNA defensive responses	12
TWIST1-mediated transcriptional activation of PDGFRβ in breast cancer stem cells promotes tumorigenesis and metastasis	12
Glutaredoxin-2 and Sirtuin-3 deficiencies impair cardiac mitochondrial energetics but their effects are not additive	12
Splice variants of metabolic nuclear receptors: Relevance for metabolic disease and therapeutic targeting	12
Glycemic homeostasis and hepatic metabolism are modified in rats with global cerebral ischemia	12
Impact of maternal nutrition in viral infections during pregnancy	12
TGF-β/YB-1/Atg7 axis promotes the proliferation of hepatic progenitor cells and liver fibrogenesis	12
Klotho restoration via ACE2 activation: A potential therapeutic strategy against acute kidney injury-diabetes comorbidity	12
Analysis of cathepsin B and cathepsin L treatment to clear toxic lysosomal protein aggregates in neuronal ceroid lipofuscinosis	12
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis	12
Deletion of Mcpip1 in Mcpip1fl/flAlbCre mice recapitulates the phenotype of human primary biliary cholangitis	12
Senescent cardiac fibroblasts: A key role in cardiac fibrosis	12
Dietary fructose as a model to explore the influence of peripheral metabolism on brain function and plasticity	12
Comparison of the renal effects of bisphenol A in mice with and without experimental diabetes. Role of sexual dimorphism	11
Adipocyte coculture induces a pro-inflammatory, fibrotic, angiogenic, and proliferative microenvironment in uterine leiomyoma cells	11
GLI1-targeting drugs induce replication stress and homologous recombination deficiency and synergize with PARP-targeted therapies in triple negative breast cancer cells	11
GPX1-associated prognostic signature predicts poor survival in patients with acute myeloid leukemia and involves in immunosuppression	11
Cannabinol modulates neuroprotection and intraocular pressure: A potential multi-target therapeutic intervention for glaucoma	11
WNT7B represses epithelial-mesenchymal transition and stem-like properties in bladder urothelial carcinoma	11
Comparative transcriptome analysis of human and murine choroidal neovascularization identifies fibroblast growth factor inducible-14 as phylogenetically conserved mediator of neovascular age-related m	11
Inhibition of myeloid differentiation factor 2 attenuates cardiometabolic impairments via reducing cardiac mitochondrial dysfunction, inflammation, apoptosis and ferroptosis in prediabetic rats	11
The role of RNA-binding and ribosomal proteins as specific RNA translation regulators in cellular differentiation and carcinogenesis	11
Trained immunity in viral infections, Alzheimer's disease and multiple sclerosis: A convergence in type I interferon signalling and IFNβ-1a	11
NCS 613, a PDE4 inhibitor, by increasing cAMP level suppresses systemic inflammation and immune complexes deposition in kidney of MRL/lpr lupus- prone mice	11
Signalling transduction of O-GlcNAcylation and PI3K/AKT/mTOR-axis in prostate cancer	11
The secretome of senescent preadipocytes influences the phenotype and function of cells of the vascular wall	11
Deubiquitylase PSMD14 inhibits autophagy to promote ovarian cancer progression via stabilization of LRPPRC	11
Connexin hemichannel inhibitors with a focus on aminoglycosides	11
Effect of oxidative stress on telomere maintenance in aortic smooth muscle cells	11
Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis	11
Hydroxyproline stimulates inflammation and reprograms macrophage signaling in a rat kidney stone model	11
Recent advances in understanding the molecular mechanisms of cholestatic pruritus: A review	11
Macrophage-specific MyD88 deletion and pharmacological inhibition prevents liver damage in non-alcoholic fatty liver disease via reducing inflammatory response	10
Stimulation of cholesterol biosynthesis in mitochondrial complex I-deficiency lowers reductive stress and improves motor function and survival in mice	10
Excessive DNA damage mediates ECM degradation via the RBBP8/NOTCH1 pathway in sporadic aortic dissection	10
Comprehensive analysis of ceRNA networks in HPV16- and HPV18-mediated cervical cancers reveals XIST as a pivotal competing endogenous RNA	10
The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice	10
Fluorofenidone ameliorates cholestasis and fibrosis by inhibiting hepatic Erk/-Egr-1 signaling and Tgfβ1/Smad pathway in mice	10
Pan-cancer analysis of Chromobox (CBX) genes for prognostic significance and cancer classification	10
Icariin attenuates excessive alcohol consumption-induced susceptibility to atrial fibrillation through SIRT3 signaling	10
Functional consequences of SARS-CoV-2 infection in pregnant women, fetoplacental unit, and neonate	10
Oxidative modification impairs SERCA activity in Drosophila and human cell models of Parkinson's disease	10
The ameliorating effects of metformin on disarrangement ongoing in gastrocnemius muscle of sarcopenic and obese sarcopenic mice	10
YAP1-TEAD1 mediates the perineural invasion of prostate cancer cells induced by cancer-associated fibroblasts	10
Alteration of mitochondrial supercomplexes assembly in metabolic diseases	10
TLR4 expression and functionality are downregulated in glioblastoma cells and in tumor-associated macrophages: A new mechanism of immune evasion?	10
Clotrimazole presents anticancer properties against a mouse melanoma model acting as a PI3K inhibitor and inducing repolarization of tumor-associated macrophages	10
Sex-dependent effects on the gut microbiota and host metabolome in type 1 diabetic mice	10
Systemic lupus erythematosus is associated with impaired autophagic degradation via interleukin-6 in macrophages	10
Gene expression analysis identifies two distinct molecular clusters of idiopatic epiretinal membranes	10
Caspase-3 and gasdermin E detection in peri-implantitis	10
Starvation and pH stress conditions induced mitochondrial dysfunction, ROS production and autophagy in Trypanosoma cruzi epimastigotes	10
Recognizing novel chemicals/drugs for anatomical therapeutic chemical classes with a heat diffusion algorithm	10
Mice with dysfunctional TGF-β signaling develop altered intestinal microbiome and colorectal cancer resistant to 5FU	10
Connexin channels modulation in pathophysiology and treatment of immune and inflammatory disorders	10
Platelet activation and ferroptosis mediated NETosis drives heme induced pulmonary thrombosis	10
Insulin injections inhibits PTZ-induced mitochondrial dysfunction, oxidative stress and neurological deficits via the SIRT1/PGC-1α/SIRT3 pathway	10
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression	10
Virus morphology: Insights from super-resolution fluorescence microscopy	10
Advanced nanoscale drug delivery systems for bone cancer therapy	10
Over-activated hemichannels: A possible therapeutic target for human diseases	10
Inhibition of YAP by lenvatinib in endothelial cells increases blood pressure through ferroptosis	10
Hypusination of Eif5a regulates cytoplasmic TDP-43 aggregation and accumulation in a stress-induced cellular model	10
Functional analysis of three Nav1.6 mutations causing early infantile epileptic encephalopathy	10
Changes in glomerular filtration rate and metabolomic differences in severely ill coronavirus disease survivors 3 months after discharge	9