OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Biomolecular Nmr is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Protein in-cell NMR spectroscopy at 1.2 GHz	44
Paramagnetic NMR in drug discovery	39
Biomolecular solid-state NMR spectroscopy at 1200 MHz: the gain in resolution	39
CCMRD: a solid-state NMR database for complex carbohydrates	36
The precious fluorine on the ring: fluorine NMR for biological systems	30
FID-Net: A versatile deep neural network architecture for NMR spectral reconstruction and virtual decoupling	30
NMR quality control of fragment libraries for screening	21
Fluorine NMR functional screening: from purified enzymes to human intact living cells	20
A suite of 19F based relaxation dispersion experiments to assess biomolecular motions	18
CheSPI: chemical shift secondary structure population inference	17
Probing conformational transitions towards mutagenic Watson–Crick-like G·T mismatches using off-resonance sugar carbon R1ρ relaxation dispersion	14
Measuring transverse relaxation in highly paramagnetic systems	13
Multi-receiver solid-state NMR using polarization optimized experiments (POE) at ultrafast magic angle spinning	12
MAS NMR detection of hydrogen bonds for protein secondary structure characterization	12
Detecting aspartate isomerization and backbone cleavage after aspartate in intact proteins by NMR spectroscopy	11
Principal component analysis for automated classification of 2D spectra and interferograms of protein therapeutics: influence of noise, reconstruction details, and data preparation	11
NMR in target driven drug discovery: why not?	11
NMR spectroscopy: the swiss army knife of drug discovery	10
RING NMR dynamics: software for analysis of multiple NMR relaxation experiments	10
Clustered sparsity and Poisson-gap sampling	10
A COVID moonshot: assessment of ligand binding to the SARS-CoV-2 main protease by saturation transfer difference NMR spectroscopy	9
CcpNmr AnalysisScreen, a new software programme with dedicated automated analysis tools for fragment-based drug discovery by NMR	9
NMR refinement and peptide folding using the GROMACS software	9
Efficient production of a functional G protein-coupled receptor in E. coli for structural studies	9
Development of in vitro-grown spheroids as a 3D tumor model system for solid-state NMR spectroscopy	9

Protein NMR of biologicals: analytical support for development and marketed products	8
Deleterious effects of carbon–carbon dipolar coupling on RNA NMR dynamics	8
Optimized selection of slow-relaxing 13C transitions in methyl groups of proteins: application to relaxation dispersion	8
HACANCOi: a new Hα-detected experiment for backbone resonance assignment of intrinsically disordered proteins	8
Molecular chaperones and their denaturing effect on client proteins	8
Dynamic 15N{1H} NOE measurements: a tool for studying protein dynamics	8
Measurement of 1Hα transverse relaxation rates in proteins: application to solvent PREs	8
The measurement of binding affinities by NMR chemical shift perturbation	8
NMR in integrated biophysical drug discovery for RAS: past, present, and future	8
Protein—ligand structure determination with the NMR molecular replacement tool, NMR2	8
How wide is the window opened by high-resolution relaxometry on the internal dynamics of proteins in solution?	8
Spectral editing of alanine, serine, and threonine in uniformly labeled proteins based on frequency-selective homonuclear recoupling in solid-state NMR	7
Efficient affinity ranking of fluorinated ligands by 19F NMR: CSAR and FastCSAR	7
Monitoring protein unfolding transitions by NMR-spectroscopy	7
A CEST NMR experiment to obtain glycine 1Hα chemical shifts in ‘invisible’ minor states of proteins	7
Glutamine-free mammalian expression of recombinant glycoproteins with uniform isotope labeling: an application for NMR analysis of pharmaceutically relevant Fc glycoforms of human immunoglobulin G1	7
Towards autonomous analysis of chemical exchange saturation transfer experiments using deep neural networks	7
TRACT revisited: an algebraic solution for determining overall rotational correlation times from cross-correlated relaxation rates	7
The role of NMR in leveraging dynamics and entropy in drug design	7
Site-specific resolution of anionic residues in proteins using solid-state NMR spectroscopy	7
NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide–dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei	6
NMR pseudocontact shifts in a symmetric protein homotrimer	6
Reducing the measurement time of exact NOEs by non-uniform sampling	6
Band-selective universal 90° and 180° rotation pulses covering the aliphatic carbon chemical shift range for triple resonance experiments on 1.2 GHz spectrometers	6
1H-detected characterization of carbon–carbon networks in highly flexible protonated biomolecules using MAS NMR	6
Backbone assignments and conformational dynamics in the S. typhimurium tryptophan synthase α-subunit from solution-state NMR	6
Optimization and validation of multi-state NMR protein structures using structural correlations	6
The methyl 13C-edited/13C-filtered transferred NOE for studying protein interactions with short linear motifs	6
Fundamental and practical aspects of machine learning for the peak picking of biomolecular NMR spectra	5
Revisiting biomolecular NMR spectroscopy for promoting small-molecule drug discovery	5
Optimized precursor to simplify assignment transfer between backbone resonances and stereospecifically labelled valine and leucine methyl groups: application to human Hsp90 N-terminal domain	5
An automated iterative approach for protein structure refinement using pseudocontact shifts	5
The time-zero HSQC method improves the linear free energy relationship of a polypeptide chain through the accurate measurement of residue-specific equilibrium constants	5
Assessing the applicability of 19F labeled tryptophan residues to quantify protein dynamics	4
Optimizing frequency sampling in CEST experiments	4
Evaluation of the tert-butyl group as a probe for NMR studies of macromolecular complexes	4
A novel high-dimensional NMR experiment for resolving protein backbone dihedral angle ambiguities	4
A simple and cost-effective protocol for high-yield expression of deuterated and selectively isoleucine/leucine/valine methyl protonated proteins in Escherichia coli grown in shaker flasks	4
Quantifying the effects of long-range 13C-13C dipolar coupling on measured relaxation rates in RNA	4
Protein resonance assignment by solid-state NMR based on 1H-detected 13C double-quantum spectroscopy at fast MAS	4
Efficient solvent suppression with adiabatic inversion for 1H-detected solid-state NMR	4