OOIR: Observatory of International Research

Papers

(The TQCC of European Neuropsychopharmacology is 0. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Valproate's impact on future generations — A call for stricter guidelines for maternal and paternal use	281
Psilocybin intoxication did not affect daytime or sleep-related declarative memory consolidation in a small sample exploratory analysis	264
Multi-omics data integration methods and their applications in psychiatric disorders	97
Emotional intelligence and neurocognition profiles in first-episode psychosis: A two-year follow-up study	73
P.0160 Clinical and demographic features in delusional disorder: a descriptive study from Turkey	58
Expert consensus recommendations on the use of randomized clinical trials for drug approval in psychiatry- comparing trial designs	50
A pacemaker for happiness – Transcutaneous vagus nerve stimulation in depression	47
TU16. BRAINXCAN IDENTIFIES BRAIN FEATURES ASSOCIATED WITH BEHAVIORAL AND PSYCHIATRIC TRAITS USING LARGE SCALE GENETIC AND IMAGING DATA	45
Clozapine dosing patterns and clinical outcomes in patients with treatment resistant schizophrenia	45
Neurocognitive functions in persistent negative symptoms following a first episode of psychosis	43
GLP-1 agonists and risk of suicidal thoughts and behaviours: Confound by indication once again? A narrative review	40
Challenges in testing concentrated cognitive-behaviour therapy for unmedicated adults with obsessive-compulsive disorder in routine care	39
Citizen participation processes in mental health: Does it help or worsen things?	39
Dissecting the role of CB1 and CB2 receptors in cannabinoid reward versus aversion using transgenic CB1- and CB2-knockout mice	38
Psychotropic drugs consumption during 2020 COVID-19 pandemic and lockdowns: Evidence of a surprising resilience of the drugs delivery system in France	38
Self-reported neurocognitive symptoms during COVID-19 lockdown and its associated factors in a sample of psychiatric patients. Results from the BRIS-MHC study	37
Minor physical anomalies in schizophrenia and first-degree relatives in comparison to healthy controls: A systematic review and meta-analysis	36
Suicide mortality in Spain during the COVID-19 pandemic: Longitudinal analysis of sociodemographic factors	36
Corrigendum to “34th ECNP Congress – Lisbon 2021 Hybrid. [34th ECNP Congress – Lisbon 2021 Hybrid. 53S1. December 2021]” P.0576 Knockdown of 5-HT1A receptor silencer Freud-2 in the frontal cortex affe	35
T32. GENETIC ARCHITECTURE OF BIPOLAR SPECTRUM DISORDERS IN NEARLY 102,000 LATINO ANCESTRY INDIVIDUALS	34
W92. POLYGENIC RISK SCORES INDICATES GENETIC OVERLAP BETWEEN METHAMPHETAMINE USE AND OTHER PSYCHIATRIC DISORDERS	32
T78. GENE-ENVIRONMENT INTERACTION STUDY ON THE CORRELATES FOR PSYCHOTIC EXPERIENCES IN THE UK BIOBANK	31
F8. THE DEVELOPMENTAL LANDSCAPE OF NEUROPSYCHIATRIC GENOMICS IN AFRICA	30
85. EXTENSIVE GENETIC INTERACTIONS (EPISTASIS) IDENTIFIED FOR ALCOHOL USE DISORDER IN A HIGH-RISK AMERICAN INDIAN POPULATION	29
EXPLORING MENTAL HEALTH STIGMA IN THE CONTEXT OF PSYCHIATRIC GENETICS: INSIGHTS FROM THE ISPG STIGMA REDUCTION SIG SURVEY	29

69. LARGE-SCALE GENETIC INVESTIGATION OF TRAIT-BASED RESILIENCE USING THE CONNOR-DAVIDSON RESILIENCE SCALE (CD-RISC)	28
40. NOVEL FINDINGS FROM TRANSCRIPTOME-WIDE ASSOCIATION STUDIES OF 5 MAJOR PSYCHIATRIC DISORDERS USING ANCESTRALLY DIVERSE GENE EXPRESSION MODELS	26
42. STRESS EXPOSURE DYNAMICALLY REGULATES EQTL ACTIVITY IN THE POST-MORTEM BRAIN AND IN HIPSC-DERIVED NEURONS	26
W6. DEVELOPMENT OF PSYCHIATRIC GENOMICS RESEARCH IN AFRICA: A SYSTEMATIC LITERATURE REVIEW	26
6. DECIPHERING NEURONAL NETWORK DEFECTS IN SCHIZOPHRENIA USING MICROFLUIDIC CULTURES	26
POLYGENIC ARCHITECTURE AND DISEASE RISK PREDICTION	26
EVALUATING THE IMPACT OF BIOLOGICAL SEX ON ADHD PRESENTATION, PREVALENCE, AND GENETIC RISK	26
W1. MULTI-ANCESTRY EPIGENETIC INVESTIGATION OF GENERALIZED ANXIETY DISORDER IN THE MILLION VETERAN PROGRAM	24
COORDINATED EPISTASIS DETECTS HETEROGENOUS PATHWAYS ACROSS PSYCHIATRIC DISORDERS AND COMORBIDITIES	24
NEW INSIGHTS INTO THE GENETIC ETIOLOGY AND THERAPEUTIC TARGETS OF SCHIZOPHRENIA	24
INTRODUCING MIND: THE METHYLATION, IMAGING AND NEURODEVELOPMENT CONSORTIUM	24
60. SEX-STRATIFIED SINGLE-CELL ANALYSIS UNCOVERS GENE EXPRESSION DIFFERENCES IN SCHIZOPHRENIA, BIPOLAR DISORDER, AND AUTISM	24
39. POLYGENIC SCORES FOR PSYCHIATRIC DISORDERS PREDICT QUANTITATIVE SYMPTOM SCORES IN THE POPULATION LARGELY DUE TO THE PERVASIVE GENETIC INFLUENCE OF GENERAL PSYCHOPATHOLOGY (P)	24
W11. TRANSDIAGNOSTIC AND FAMILIAL INSIGHTS INTO PREFRONTAL CORTEX FUNCTIONALITY: A RESTING-STATE FNIRS STUDY	24
11. ESTABLISHING THE MOLECULAR FOUNDATION OF BRAIN ANATOMY IN LIVING INDIVIDUALS	23
79. DECIPHERING THE GENETIC ARCHITECTURE OF TOURETTE SYNDROME: A LARGE-SCALE GWAS REVEALS NOVEL RISK LOCI AND HIGHLIGHTS BRAIN REGION SPECIFICITY	23
LEVERAGING GENETIC PLEIOTROPY IN DRUG TARGET DISCOVERY FOR PSYCHIATRIC DISORDERS	23
33. ASSOCIATIONS OF POLYGENIC RISKS FOR SCHIZOPHRENIA, BIPOLAR DISORDER, AND DEPRESSION WITH SYMPTOM DIMENSIONS AND TREATMENT OUTCOMES IN SCHIZOPHRENIA	23
41. CHARACTERIZING FUNCTIONAL CONVERGENCE OF COMMON POLYGENIC VARIATION IN NEUROPSYCHIATRIC DISORDER RISK GENES	22
W47. PSYCHIATRIC AND CARDIOMETABOLIC COMORBIDITIES OF TREATMENT-RESISTANT DEPRESSION	22
T58. EXPLORATION OF GENETIC AND CLINICAL HETEROGENEITY IN AUTISM BY CLUSTERING GENES BASED ON BULK AND SINGLE-CELL TRANSCRIPTOMIC DATA	21
T13. GENETIC ASSOCIATIONS OF ICD-DERIVED PSYCHIATRIC DIAGNOSES WITH SELF-REPORTED MENTAL HEALTH PHENOTYPES IN THE UK BIOBANK	21
T56. DIP2A, HIGHLY EXPRESSED GENE IN THE CEREBELLUM, IS ASSOCIATED WITH A WIDE RANGE OF PSYCHIATRIC SYMPTOMS (DELAYED SPEECH, AUTISM SPECTRUM DISORDER AND SPECIFIC LEARNING DISABILITIES)	21
W14. POLYGENIC PREDICTION OF CONDITIONED FEAR RESPONSES	21
T51. LARGE-SCALE WHOLE-GENOME SEQUENCING ANALYSIS REVEALS A HIGHER-THAN-EXPECTED PREVALENCE OF C9ORF72 REPEAT EXPANSION ALLELES ASSOCIATED WITH SPECIFIC HAPLOTYPE STRUCTURE IN THE GENERAL POPULATION	21
W44. THE INFLUENCE OF INFLAMMATORY CYTOKINE GENETIC VARIANTS ON SYMPTOM SEVERITY IN THE PSYCOURSE STUDY	21
W73. GENETIC AND SOCIOENVIROMENTAL CORRELATES OF SYMPTOM DIMENSIONS ACROSS THE PSYCHOSIS SPECTRUM AT BASELINE AND 10-YEAR FOLLOW-UP	21
T27. FEMA-GWAS: FAST AND EFFICIENT MIXED-EFFECTS ALGORITHM FOR DISCOVERY OF GENOME-WIDE AGE-DEPENDENT EFFECTS	21
56. GENOME WIDE ASSOCIATION STUDY OF SCHIZOPHRENIA IN THE NEUROPSYCHIATRIC GENETICS IN AFRICAN POPULATION-PSYCHOSIS (NEUROGAP-PSYCHOSIS) STUDY	21
W82. ASSOCIATION OF GENETIC VARIATION IN ANTIDIABETIC DRUG TARGET GENES AND PSYCHIATRIC DISORDERS: A MENDELIAN RANDOMIZATION STUDY	21
T84. AN INVESTIGATION ON GENETIC MECHANISMS UNDER CLINICAL HETEROGENEITY IN SCHIZOPHRENIA	21
F42. MOLECULAR EFFECTS OF ADVERSE LIFE EVENTS IN A DIVERSE POPULATION OF POSTPARTUM WOMEN	20
F22. EPIGENETIC INSIGHTS INTO OBSESSIVE-COMPULSIVE DISORDER THROUGH A META-EWAS APPROACH	20
W72. GENETIC INSIGHTS INTO COGNITIVE FUNCTION: A GWAS OF ASIAN ANCESTRY USING MULTI-TRAIT ANALYSIS	20
T47. A MULTI-OMIC QTL ANALYSIS OF MAJOR DEPRESSIVE DISORDER	20
W59. DE NOVO PROMOTER VARIANTS CONTRIBUTE TO AUTISM SPECTRUM DISORDER RISK VIA TOPOLOGICALLY ASSOCIATING DOMAINS	20
PRECISION AND ACCURACY IN SINGLE-CELL RNA-SEQ	19
T48. WHOLE-GENOME DNA METHYLATION SEQUENCING IN BLOOD IDENTIFIES DIFFERENTIAL METHYLATION IN PARKINSON'S DISEASE IN THE CHINESE HAN POPULATION	19
F18. ROLE OF PSYCHIATRIC-ASSOCIATED SNVS IN THE EARLY ADULTHOOD: INSIGHTS FROM LONGITUDINAL NEUROIMAGING	19
F41. AMBER: ANTIDEPRESSANT MEDICATIONS: BIOLOGY, EXPOSURE AND RESPONSE	19
SCIENCE COMMUNICATION: THE IMPORTANCE OF LANGUAGE IN A DIVERSE WORLD	18
70. GENOME-WIDE ASSOCIATION STUDY OF BORDERLINE PERSONALITY DISORDER IDENTIFIES SIX GENETIC RISK LOCI AND REVEALS SHARED GENETIC RISK WITH OTHER MENTAL DISORDERS AND RISK FACTORS	18
27. HOW “DYSLEXIA GENES” INFLUENCE BRAIN STRUCTURE AND CONNECTIVITY?	18
31. SCHIZOPHRENIA GENETIC RISK AND CELL-SPECIFIC DIFFERENTIAL EXPRESSION ARE LINKED TO GENE REGULATORY NETWORKS FOR CELL MATURATION THAT PATTERN THE TRANSCRIPTIONAL ARCHITECTURE OF THE HUMAN CORTEX	18
W35. SHARED GENETIC ARCHITECTURE BETWEEN INFLAMMATORY PROCESSES AND DEPRESSION: EXPLORING GENETIC CORRELATIONS, OVERLAP AND CAUSALITY	17
F51. EPIGENOME-WIDE ASSOCIATION STUDY OF READING AND LANGUAGE TRAITS	17
T16. THE ASSOCIATION BETWEEN DEPRESSION POLYGENICITY AND DISEASE ACTIVITY AND DISABILITY WORSENING IN MULTIPLE SCLEROSIS	17
W76. INVESTIGATION OF DE NOVO MUTATIONS IN SCHIZOPHRENIA AFFECTED INDIAN FAMILIES	17
T21. COMMON AND RARE GENETIC ARCHITECTURE OF COMORBIDITY BETWEEN CARDIOVASCULAR DISEASES AND SEVERE MENTAL DISORDERS	17
TREATMENT RESISTANCE IN SCHIZOPHRENIA: UTILITY OF POLYGENIC RISK SCORES	17

T59. THE CONNECTION BETWEEN ADHD AND ACADEMIC ACHIEVEMENT IN CONTRASTING ENVIRONMENTS	16
F16. BRAIN CARTOGRAPHY OF GENOME-WIDE POLYGENIC RISK THROUGH SPATIAL TRANSCRIPTOMICS PREDICTS BRAIN STRUCTURE IN MAJOR PSYCHIATRIC DISORDERS	16
T96. DELTA-9-TETRAHYDROCANNABINOL MODULATES IMMUNOGENOMIC FUNCTION AT SINGLE CELL RESOLUTION USING 10X MULTIOME PROFILING: IN VIVO HUMAN SUBJECT STUDY	16
F70. INTEGRATION OF MULTI-OMICS SUMMARY DATA REVEALS THE ROLE OF N6-METHYLADENOSINE METHYLATION IN NEUROPSYCHIATRIC DISORDERS	15
UPDATE FROM THE “PEDIGREE-BASED WHOLE GENOME SEQUENCING OF AFFECTIVE AND PSYCHOTIC DISORDERS" CONSORTIUM	14
F97. DIFFERENTIAL EXPRESSION OF MICRORNAS UPON IN VITRO LITHIUM AND VALPROATE EXPOSURE TO BIPOLAR DISORDER PATIENTS-DERIVED LCLS	14
F38. THE CLINICAL UTILITY OF POLYGENIC SCORES FOR PREDICTING LITHIUM TREATMENT RESPONSE IN PATIENTS WITH BIPOLAR DISORDER: CHARTING THE PATH FORWARD	14
T29. SPATIAL-MOLECULAR SEX DIFFERENCES IN THE HUMAN VENTROMEDIAL AND ARCUATE HYPOTHALAMUS	14
INNATE AND ADAPTIVE IMMUNITY IN PSYCHIATRY: INSIGHTS FROM GENETIC ASSOCIATION STUDIES AND PERIPHERAL BLOOD IMMUNOPHENOTYPING	14
F35. INVESTIGATING GENETIC RISK FOR PSYCHOSIS IN BIPOLAR DISORDER IN INDIA USING POLYGENIC SCORES	14
T100. CHILD SUBCORTICAL BRAIN VOLUMES: THE INTERACTION BETWEEN GENETIC RISK AND MATERNAL PSYCHOLOGICAL DISTRESS DURING PREGNANCY	14
F75. PREDICTION OF TREATMENT-RESISTANT SCHIZOPHRENIA USING REAL-WORLD DATA AND MULTIMODAL ANALYTICAL TOOLS	14
DRUG REPOSITIONING ANALYSIS IDENTIFIED HUNDREDS OF NOVEL COMPOUNDS ASSOCIATED WITH TOBACCO USE DISORDER	14
59. UNVEILING CELL-TYPE-SPECIFIC CHANGES IN SCHIZOPHRENIA: INSIGHTS FROM CELL COMPOSITION, GENE EXPRESSION, AND GENETIC RISK ENRICHMENT	14
F30. DECONSTRUCTION OF MENTAL DISABILITY CLASSIFICATION STRATIFIES CHRONIC PSYCHIATRIC AND NEUROLOGICAL OUTCOME AND IDENTIFIES OUTCOME-RELEVANT ACUTE FACTORS FOR PATIENTS WITH TRAUMATIC BRAIN INJURY	14
T83. CONTRIBUTION OF COPY NUMBER VARIANTS ON ANTIPSYCHOTIC TREATMENT RESPONSE IN HAN CHINESE PATIENTS WITH SCHIZOPHRENIA	14
P.0516 Genotype rs25531 polymorphisms and quality in peer relationships adjust the neural response of the anterior prefrontal cortex to cry	13
Biological markers of sex-based differences in major depressive disorder and in antidepressant response	13
Psychotropic drug utilization patterns in pregnant women with bipolar disorder: A 16-year population-based cohort study	13
Prescribing therapeutic apps within National Health Services: The critical role of evaluation and monitoring	13
The effects of transient receptor potential cation channel inhibition by BI 1358894 on cortico-limbic brain reactivity to negative emotional stimuli in major depressive disorder	13
DSM-5 and ICD-11 criteria for bipolar disorder: Implications for the prevalence of bipolar disorder and validity of the diagnosis – A narrative review from the ECNP bipolar disorders network	13
‘Microbiota-metabolome interaction in depression: Could it be the new 42?’	12
Comparative effectiveness of antipsychotic monotherapy and polypharmacy in schizophrenia patients with clozapine treatment: A nationwide, health insurance data-based study	12
Comparative outcomes in electroconvulsive therapy (ECT): A naturalistic comparison between outcomes in psychosis, mania, depression, psychotic depression and catatonia	12
Route map for machine learning in psychiatry: Absence of bias, reproducibility, and utility	12
Transcriptional biomarkers of response to pharmacological treatments in severe mental disorders: A systematic review	12
Rare variants and clozapine: Reply	12
Bidirectional associations between treatment-resistant depression and general medical conditions	12
Pharmacokinetic and pharmacodynamic interactions between daridorexant, a dual orexin receptor antagonist, and citalopram in healthy subjects	12
Outcomes associated with different vaccines in individuals with bipolar disorder and impact on the current COVID-19 pandemic- a systematic review	12
The clinical perspective on late-onset depression in European real-world treatment settings	12
Precision psychiatry: The complexity of personalizing antipsychotic dosing	12
P.0835 Synergistic effects of lysergic acid diethylamide (LSD) and cannabidiol (CBD)	11
Do effects of methylphenidate on cognitive performance last beyond treatment? A randomized placebo-controlled trial in boys and men with ADHD	11
A randomized controlled trial of add-on naproxen, simvastatin and their combination for the treatment of schizophrenia or schizoaffective disorder	11
Association between CACNA1C gene rs100737 polymorphism and glutamatergic neurometabolites in bipolar disorder	11
Relation of hippocampal volume and SGK1 gene expression to treatment remission in major depression is moderated by childhood maltreatment: A CAN-BIND-1 report	11
The substantia nigra in the pathology of schizophrenia: A review on post-mortem and molecular imaging findings	11
F103. A GENOME-WIDE ASSOCIATION STUDY OF USING SUBSTANCES TO COPE WITH DEPRESSION AND ANXIETY IN THE UK BIOBANK AND POLYGENIC ASSOCIATIONS WITH ALCOHOL USE DISORDER SEVERITY.	11
Whole-brain structural and functional neuroimaging of individuals who attempted suicide and people who did not: A systematic review and exploratory coordinate-based meta-analysis	11
PUSHING THE ENVELOPE WITH POLYGENIC RISK SCORES IN PSYCHIATRIC GENETICS: WHETHER, WHEN, AND HOW TO IMPLEMENT	11
Sex-specific associations of basal steroid hormones and neuropeptides with Conduct Disorder and neuroendocrine mediation of environmental risk	11
Society Calendar	11
PHENOME-WIDE GENETIC CORRELATION AND CAUSALITY OF COVID-19 SEVERITY HIGHLIGHTS OVERLAP WITH SUBSTANCE-USE TRAITS	11
CLINICAL RELEVANCE OF GENOTYPE-PHENOTYPE ANALYSES WITHIN BIPOLAR DISORDER AND ACROSS THE MOOD AND PSYCHOSIS SPECTRUM	11
ECNP Calendar of Meetings	10
27. USING A TRIO-BASED GENETIC DESIGN FOR INVESTIGATING THE AETIOLOGY OF ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD)	10
8. PHENOTYPIC MANIFESTATIONS OF GENETIC LIABILITY TO NEUROTICISM ACROSS CHILDHOOD: A UK PROSPECTIVE BIRTH COHORT STUDY	10
23. MASSIVELY PARALLEL, IN VIVO PROFILING OF MDD SNP EFFECTS ON TRANSCRIPTION ACROSS AGE, SEX, AND CELL TYPE	10
CHARACTERIZING RACISM IN PSYCHIATRIC DIAGNOSES	10
SHARED AND DISTINCT GENETIC INFLUENCES BETWEEN COGNITIVE DOMAINS AND PSYCHIATRIC DISORDER RISK BASED ON GENOME-WIDE DATA	10
Contents	10
9. ULTRA-RARE GENETIC VARIATION IN THE EPILEPSIES: A WHOLE-EXOME SEQUENCING STUDY OF 32K INDIVIDUALS	10
Exploring the link between functional connectivity of ventral tegmental area and physical fitness in schizophrenia and healthy controls	10
ECNP Calendar of Meetings	10
ANALYSIS OF COPY NUMBER VARIATION ACROSS THE MAJOR PSYCHIATRIC DISORDERS: BIPOLAR DISORDER, SCHIZOPHRENIA, AND AUTISM SPECTRUM DISORDER	10
ASSESSING THE EFFECTS OF RARE COPY NUMBER VARIANTS ON PSYCHIATRIC SYMPTOMS AND COGNITIVE ABILITY IN ∼1M INDIVIDUALS	10
The Mechanism of Akathisia - Comments on Wu et al. Eur Neuropsychopharmacol 2023;72:40–49	10
6. CONTRIBUTION OF COPY NUMBER VARIANTS TO SCHIZOPHRENIA IN EAST ASIAN POPULATIONS	10
24. WHOLE EXOME SEQUENCING META-ANALYSIS OF DEPRESSION SUGGESTS SUBTLE ROLE FOR FUNCTIONAL VARIANTS IN KNOWN GENETIC ASSOCIATION LOCI	10
Transcriptome meta-analysis of valproic acid exposure in human embryonic stem cells	10
SYMPTOM-LEVEL GENETIC MODELLING OF DEPRESSION AND ANXIETY	10
ADVERSARIAL COLLABORATION IN GENOMICS: TURNING DISAGREEMENT INTO CONSTRUCTIVE DIALOGUE	10
29. MAPPING ASSOCIATIONS BETWEEN ATTENTION-DEFICIT/HYPERACTIVITY DISORDER GENETIC LIABILITY, ATTENTION-DEFICIT/HYPERACTIVITY DISORDER SYMPTOMS, AND BEHAVIORAL AND NEURAL CORRELATES OF RESPONSE INHIBIT	9
Editorial Board	9
MENTAL HEALTH PHENOTYPING FOR GENETIC STUDIES	9
Editorial Board	9
DNA METHYLATION PARTIALLY MEDIATES THE RELATIONSHIP BETWEEN TIME-DEPENDENT CHILDHOOD ADVERSITY AND DEPRESSIVE SYMPTOMS IN ADOLESCENCE	9
33. SHARED GENETIC DETERMINANTS BETWEEN THE BRAIN FUNCTIONAL CONNECTOME AND PSYCHIATRIC DISORDERS	9
Comparing the pharmacology and pharmacokinetics of antipsychotics: Choosing an antipsychotic and dosing a long-acting injectable	9
A COMPARISON OF THREE PHENOTYPE DEFINITIONS FOR MENTAL HEALTH CONDITIONS IN THE MILLION VETERAN PROGRAM	9
EXTENSIVE POLYGENIC OVERLAP BETWEEN SCHIZOPHRENIA AND CORTICAL BRAIN STRUCTURE	9
Technology exceptionalism in medicine: Is it time to rethink the paradigm?	9
THE 4TH PSYCHIATRIC GENOMICS CONSORTIUM GRANT (2021-26): AIMS AND INTENTIONS	9
38. LATENT SUBTYPES OF MANIC OR IRRITABLE EPISODE SYMPTOMS IN TWO POPULATION-BASED COHORTS	9
ECNP Calendar of Meetings	9
Is it time to change the term negative symptoms?	9
Contents	9
T67. ASSOCIATION BETWEEN INFLAMMATORY CYTOKINE VARIANTS AND SUICIDE: AN INDIAN POPULATION-BASED STUDY	8

T86. PREDICTING PSYCHOSIS: EXPLORING THE ADDITIVE AND INTERACTION EFFECTS OF GENETIC AND EPIGENETIC RISK SCORES	8
P.0229 Characterization of positive allosteric modulators of trkb for the treatment of depression	8
T70. A COMPUTATIONAL TRANSCRIPTOMICS APPROACH TO DRUG REPURPOSING IDENTIFIES NEW THERAPEUTIC CANDIDATES FOR TREATMENT OF CHRONIC PAIN	8
P.0204 Meye web-app: translational and real-time pupillometry for studying cognitive and emotional processing	8
ECNP Calendar of Meetings	8
T46. DO SEX AND GENDER MODIFY THE EFFECT OF APOE-Ɛ4 ON NEUROCOGNITIVE IMPAIRMENT? A MULTI-ANCESTRY ANALYSIS IN THE UK BIOBANK	8
T28. COMPARISON OF QUANTITATIVE FAMILY HISTORY WITH POLYGENIC SCORES IN FAMILIES OF BIPOLAR PROBANDS	8
T80. IDENTIFICATION OF CAUSAL GENES AND PUTATIVE DRUG TARGETS FOR PARKINSON'S DISEASE AND SCHIZOPHRENIA USING STATISTICAL GENETICS TECHNIQUES	8
P.0244 Cannabidiol increased the seizure latency and reduced the mortality rate in the pentylenetetrazole-kindling model of epilepsy in rats	8
P.0234 Optogenetic shift of mesolimbic dopamine to tonic pattern reduces reward-seeking behavior	8
T74. DUPLICATION IN THE POGZ GENE AND PSYCHIATRIC MANIFESTATIONS IN TWIN BROTHERS WITH WHITE SUTTON SYNDROME	8
P.0235 Selectivity of taar1 partial agonist ro5263397 effects on drug- versus non-drug-related behaviors	8
T58. CIRCADIAN ACTIVITY AND ADHD: INTEGRATING GENOMIC DATA WITH WEARABLE TECHNOLOGY	8
P.0190 Epigenetic mechanisms underlying the stress-induced activation of serum/glucocorticoid regulated kinase 1	8
T43. INSIGHTS INTO THE GENETICS OF PERINATAL DEPRESSION VIA POLYGENIC SCORES	8
T51. MACHINE LEARNING CLASSIFICATION OF ATTENTION DEFICIT HYPERACTIVITY DISORDER USING GENOMIC CONTEXT INFORMED GENOTYPE DATA AND WITHIN-MODEL ANCESTRY ADJUSTMENT	8
P.0221 A rapid, concise and robust companion diagnostic pgx test supporting drug selection for diseases of the central nervous system	8
T87. PHENOTYPING AND IMMUNE MARKER SUB-ANALYSIS OF A NIGERIAN SCHIZOPHRENIA GWAS COHORT	8
P.0247 Assessment of sexual behavior of taar2 and taar5 knockout mice	8
T72. AUTOENCODER BASED CORRECTION OF POPULATION STRATIFICATION PER INDIVIDUAL SNP'S	8
T61. CLINICAL, GENETIC AND NEUROIMAGING ASPECTS OF ATTENTION-DEFICIT/HYPERACTIVITY DISORDER COURSES THROUGH MIDLIFE	8
T54. ASSOCIATION BETWEEN TELOMERE LENGTH AND CORTICAL THICKNESS IN ADULTS WITH ADHD	8
P.0166 Suppression of the inflammatory response in schizophrenia hipsc-derived neural progenitors: a gene-environment interaction study	8
T68. INVESTIGATING TRANSGENERATIONAL EFFECTS OF MATERNAL PSYCHOLOGICAL DISTRESS THROUGH INFANT GENE EXPRESSION PROFILES IN A SOUTH AFRICAN BIRTH COHORT STUDY	8
P.0208 Base editing therapeutic strategies for motor neuron diseases	8
T99. INTERACTIONS BETWEEN FAMILY HISTORY AND ENVIRONMENTAL FACTORS IN SCHIZOPHRENIA AND BIPOLAR DISORDER	7
F6. EXPLORING THE BIOLOGICAL RELATIONSHIPS BETWEEN IRON METABOLISM MARKERS AND PSYCHIATRIC DISORDERS	7
F30. MENTAL HEALTH RISK AND RESILIENCE DURING THE COVID-19 PANDEMIC AMONG INDIVIDUALS AT HIGH GENETIC RISK FOR BIPOLAR DISORDER	7
F71. NETWORK OF CO-METHYLATION ASSOCIATED WITH GREY MATTER MATURATION IN HUMAN ADOLESCENCE	7
BIG DATA IN DIFFERENT STUDY DESIGNS – ALL WITH THEIR OWN BIASES	7
WHOLE GENOME SEQUENCING	7
F7. THE ASSOCIATIONS BETWEEN EDUCATIONAL EXPERIENCES AND MENTAL HEALTH FROM CHILDHOOD TO YOUNG ADULTHOOD	7
T101. RARE AND COMMON VARIANTS FOR PROBLEMATIC ALCOHOL USE IDENTIFY OVERLAPPING GENE NETWORKS	7
P.0254 TRPC4/5 inhibition reverses both stress-induced excessive aversion processing and attenuated reward processing in mice	7
P.0262 Self-directed virtual care: a review of the evidence for current digital therapeutic methods in adult mental health patients	7
F34. CHARACTERISING ANTIDEPRESSANT USAGE BASED ON ELECTRONIC PRESCRIPTION RECORDS IN THE AUSTRALIAN GENETICS OF DEPRESSION STUDY	7
F94. SIGNIFICANT TELOMERE SHORTENING IN MALAYSIAN PATIENTS WITH SCHIZOPHRENIA: RELATIONSHIP WITH TOTAL ANTIOXIDANT CAPACITY AND OTHER COVARIATES	7
P.0565 Calcium salt of N-(5-hydroxynicotinoyl)-L-glutamic acid weakens depressive-like behavior and Parkinsonian syndrome in experiment on rodents	7
P.0594 Cortisol effects on brain activity and cognition (CEBAC) study: An fmri study of emotional face processing and pulsatile cortisol dynamics	7
T103. INTEGRATED ANALYSIS OF RARE EXONIC VARIANTS PROVIDES ADDITIONAL INSIGHTS INTO ALCOHOL USE DISORDER RISK	7
P.0260 Optimising a human induced pluripotent stem cell system to model the effects of il-6 on early neurodevelopment	7
P.0246 Transcriptomic analysis of trace amine-associated receptors (taars) mrna expression in the neurons of olfactory bulb of model animals	7
F15. MITOCHONDRIA-ASSOCIATED GENE NETWORK-ENVIRONMENT INTERACTION EFFECT ON THE RISK FOR IMPULSIVE BEHAVIOR AND SUBSTANCE DEPENDENCE OVER THE LIFE COURSE	7
F48. INVESTIGATING POTENTIAL RELATIONSHIPS BETWEEN PIGMENTATION GENETICS AND PARKINSON'S DISEASE (PD)	7
P.0561 Chronic treatment with iloperidone affects the cytochrome P450 2D (CYP2D) protein and activity in the brain and liver	7
P.0285 Regulation of the synaptic vesicle liquid phase by dynamic sh3 domain binding	7
P.0270 Early structural alterations in mitochondria in adult dopamine neurons induced by conditional ablation of MFN2	7
P.0356 Bariatric surgery leads to potentially favourable changes in proteins associated with neurocognitive function related to the degree of weight loss	6
P.0820 Association of resilience with limbic activity during negative emotional face processing in individuals who experienced childhood maltreatment	6
T15. DECODING GWAS SIGNALS: AN INTEGRATIVE METHOD FOR GENE PRIORITIZATION	6
P.0303 Preclinical models of neuropsychiatric disorders do not indicate impulsivity-related adverse effects of angiotensin II receptor blockers	6
PLENARY PANEL: RESEARCH TO CLINICAL APPLICATION PANEL DISCUSSION	6
T21. WEIGHT AND BIPOLAR DISORDER: A MOLECULAR PATHWAY ANALYSIS	6
P.103 Targeting nitric oxide synthase 1 adaptor protein rescues schizophrenia-related alterations in dendritic morphology	6
P.0316 Cannabis culture, consumption, and implicit cognition: behavioral findings from a cross-cultural neuroimaging study of dutch and american cannabis users	6
P.0281 Cholinergic manipulations in the ventral tegmental area and hippocampal theta rhythm in urethane-anesthetized rats	6
Gender Dysphoria and its associated hurdles in Pakistan	6
P.0350 Preference study in childhood autism spectrum disorder (asd) using childhood autism rating scale (CARS2): qualitative research and informal pilot study	6
P.0320 Depression, anxiety, psychotic-like symptoms and addiction in adolescents and adults who do and do not use cannabis	6
T6. A SYSTEMATIC REVIEW AND META-ANALYSIS OF RESEARCH USING THE AUTISM POLYGENIC SCORE	6
P.0638 Comparing the psychological impact of COVID-19 pandemic between psychiatric patients and healthy subjects: an observational retrospective study from northern Italy	6
P.0383 Switching to duloxetine following inadequate antidepressant response improves symptoms and quality of life in a prospective, real-world, observational study	6
P.0329 Sex-related differences in adult attention-deficit/hyperactivity disorder – an analysis of striatal resting-state functional connectivity	6
P.0321 Ayahuasca as a rescue treatment in depressive patients resistant to pharmacological treatment: a systematic review	6
T87. COPY-NUMBER VARIATION IN TOURETTE SYNDROME FAMILIES, ANALYSIS OF DE NOVO AND INHERITED CNVS	6
P.0391 Ultra-resistant major depression: treatment with in-esketamine on compassionate use	6
P.0814 Effects of a web-based adapted physical activity program (e-APA) on cardiorespiratory fitness and clinical symptoms in patients with schizophrenia	6
P.0312 Treatment of bipolar i disorder and alcohol use disorder dual diagnosis using opioid antagonists	6
THE BROAD ARRAY OF COLLABORATIVE OPPORTUNITIES WITH REGENERON	6
P.0632 The added value of cognitive behavioral therapy on quality of life in combination with pharmacotherapy in adults with ADHD	6
T67. ASSOCIATIONS BETWEEN METHYLATION AGE AND BRAIN AGE IN LATE ADOLESCENCE	6
P.0357 Effect of a combination therapy with cannabidiol and β-caryophyllene in SCN1A-A1783V mice, an experimental model of dravet syndrome	6
P.107 Hippocampal GABA-A α5 receptor subunits are down-regulated in the methylazoxymethanol model of schizophrenia	6
P.0322 Assessing the role of impulsivity in criminal recidivism: a preliminary observational study	6
T91. LARGE-SCALE ANALYSIS WITH SOFTWARE CONTAINERS IN ENIGMA-CNV – AN INTERNATIONAL WORKING GROUP TO STUDY RECURRENT COPY NUMBER VARIANTS AND BRAIN MEASURES	6
T8. TREATMENT WITH GALANTAMINE IN 15Q13.3 DELETIONS: GENOMICALLY-INFORMED PRECISION MEDICINE STRATEGIES IN NEURODEVELOPMENTAL DISORDERS	6
T35. SHARED GENETIC LIABILITY FOR ALCOHOL CONSUMPTION, ALCOHOL PROBLEMS, AND SUICIDAL BEHAVIOR: EVALUATING THE ROLE OF IMPULSIVITY	5
P.119 Manipulation of cholesterol metabolism in the dorsal striatum reduces cocaine-seeking in rats	5
A QUANTITATIVE MEASURE OF TREATMENT RESISTANCE IN DEPRESSION TO IMPROVE POWER OF CLINICAL AND GENETIC STUDIES	5
P.0564 Active suicidal ideation one year after the beginning of COVID-19 pandemic in a large spanish sample: risk and protective factors	5
T127. AUTOMATED PHENOTYPING OF DEPRESSIVE DISORDERS AND SYMPTOMS APPLIED TO THE ELECTRONIC MEDICAL RECORD OF THE YALE NEW HAVEN HEALTH SYSTEM	5
THE ASSOCIATION BETWEEN POLYGENIC RISK FOR SCHIZOPHRENIA AND BRAIN AGE IN A POPULATION-BASED SAMPLE OF YOUNG ADULTS: A RECALL-BY-GENOTYPE-BASED APPROACH	5
T19. THE GENETIC BASIS OF MANIC SYMPTOMS IN INDIVIDUALS WITH DEPRESSION AND ANXIETY	5
P.0426 Proof-of-concept study testing SOM3355 for the treatment of chorea symptoms in Huntington's disease	5
AN AUTOMATIC PIPELINE FOR BRAIN BULK TISSUE RNA-SEQ CELL TYPE DECOMPOSITION	5
T107. INDIVIDUALS WITH SEVERE PSYCHOPATHOLOGY SYMPTOMS AND AFRICAN AMERICAN INDIVIDUALS ARE UNDERREPRESENTED IN SCHIZOPHRENIA GENETICS RESEARCH	5
A MULTIVARIATE GENETIC ANALYSIS OF ENVIRONMENTAL SENSITIVITY, ANXIETY SENSITIVITY AND PERCEPTION OF LIFE EVENTS IN ADOLESCENTS	5
CHALLENGES AND OPPORTUNITIES FOR DEVELOPING MORE GENERALIZABLE POLYGENIC RISK SCORES	5
P.0352 Avoidant/Restrictive food intake disorder in adult female treated with attachment-based therapy and cognitive behavioral therapy: case report	5
T121. MULTI-OMIC NETWORK ANALYSIS IDENTIFIES KEY NEUROBIOLOGICAL PATHWAYS IN OPIOID ADDICTION	5
P.106 Epigenome-wide DNA methylation in externalizing behaviours: a review and meta-analysis	5
GENETIC PREDISPOSITION FOR BIPOLAR DISORDER IS REFLECTED IN ECOLOGICALLY ASSESSED MOOD AND PHYSICAL ACTIVITY	5
P.0425 Link between multiple system atrophy and lysosomal storage disorders	5
P.0442 Involvement of beta amyloid 1-42 in amino acid transportation into astrocytes and immunoreactive hypofunction	5
T130. INCREASED DEPRESSION POLYGENIC SCORES ASSOCIATE WITH WORSE ANTIDEPRESSANT RESPONSE FROM ELECTRONIC HEALTH RECORDS	5