OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Dermatological Science is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Atopic dermatitis: Role of the skin barrier, environment, microbiome, and therapeutic agents	103
Multiple roles of macrophage in skin	51
The nationwide epidemiological survey of Stevens-Johnson syndrome and toxic epidermal necrolysis in Japan, 2016-2018	35
Possible treatment for UVB-induced skin injury: Anti-inflammatory and cytoprotective role of metformin in UVB-irradiated keratinocytes	35
Telogen Effluvium – a review of the science and current obstacles	35
HOXA11-AS facilitates the proliferation, cell cycle process and migration of keloid fibroblasts through sponging miR-188–5p to regulate VEGFA	33
Successful dupilumab treatment for ichthyotic and atopic features of Netherton syndrome	31
A new deep learning approach integrated with clinical data for the dermoscopic differentiation of early melanomas from atypical nevi	28
Polyphenol treatments increase elastin and collagen deposition by human dermal fibroblasts; Implications to improve skin health	27
Gut microbiota characterization in Chinese patients with alopecia areata	25
Immunomodulating role of the JAKs inhibitor tofacitinib in a mouse model of bleomycin-induced scleroderma	25
Pustular psoriasis as an autoinflammatory keratinization disease (AiKD): Genetic predisposing factors and promising therapeutic targets	24
Molecular insights of human skin epidermal and dermal aging	24
Pro-inflammatory Vδ1+T-cells infiltrates are present in and around the hair bulbs of non-lesional and lesional alopecia areata hair follicles	23
Tissue cytokine/chemokine profile in vulvar lichen sclerosus: An observational study on keratinocyte and fibroblast cultures	22
Clinical and histopathological views of morbilliform rash after COVID-19 mRNA vaccination mimic those in SARS-CoV-2 virus infection-associated cutaneous manifestations	22
Utility of the Dermatology Life Quality Index at initiation or switching of biologics in real-life Japanese patients with plaque psoriasis: Results from the ProLOGUE study	21
Fine particulate matter (PM2.5) promotes IgE-mediated mast cell activation through ROS/Gadd45b/JNK axis	21
Interferon-α inducible protein 6 (IFI6) confers protection against ionizing radiation in skin cells	20
A microbiome study to explore the gut-skin axis in hidradenitis suppurativa	20
Activation of aryl hydrocarbon receptor in Langerhans cells by a microbial metabolite of tryptophan negatively regulates skin inflammation	20
Antifibrotic effects and mechanisms of mesenchymal stem cell-derived exosomes in a systemic sclerosis mouse model: Possible contribution of miR-196b-5p	19
Serum levels of miRNA-21-5p in vitiligo patients and effects of miRNA-21-5p on SOX5, beta-catenin, CDK2 and MITF protein expression in normal human melanocytes	19
Anti-inflammatory effects of differential molecular weight Hyaluronic acids on UVB-induced calprotectin-mediated keratinocyte inflammation	18
Large-scale plasma-metabolome analysis identifies potential biomarkers of psoriasis and its clinical subtypes	18

Oncostatin M sensitizes keratinocytes to UVB-induced inflammation via GSDME-mediated pyroptosis	17
A novel role of IL-17A in contributing to the impaired suppressive function of Tregs in psoriasis	17
Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients	17
Suppression of neuropeptide by botulinum toxin improves imiquimod-induced psoriasis-like dermatitis via the regulation of neuroimmune system	17
Vitamin D3 analogue facilitates epithelial wound healing through promoting epithelial-mesenchymal transition via the Hippo pathway	16
Nicotinamide mononucleotide reduces melanin production in aged melanocytes by inhibiting cAMP/Wnt signaling	16
H3K27Ac modification and gene expression in psoriasis	16
N6-methyladenosine-modified long non-coding RNA AGAP2-AS1 promotes psoriasis pathogenesis via miR-424–5p/AKT3 axis	15
Ultraviolet B induces proteolytic cleavage of the pyroptosis inducer gasdermin E in keratinocytes	15
Argan (Argania Spinosa) press cake extract enhances cell proliferation and prevents oxidative stress and inflammation of human dermal papilla cells	15
The pathogeneses of pemphigus and pemphigoid diseases	15
Keloid fibroblasts have elevated and dysfunctional mechanotransduction signaling that is independent of TGF-β	14
Convolutional neural network-based skin image segmentation model to improve classification of skin diseases in conventional and non-standardized picture images	14
A multicenter, open-label, uncontrolled, single-arm phase 2 study of tirabrutinib, an oral Bruton’s tyrosine kinase inhibitor, in pemphigus	14
The involvement of ERK1/2 and p38 MAPK in the premature senescence of melanocytes induced by H2O2 through a p53-independent p21 pathway	14
Resveratrol ameliorates lipid accumulation and inflammation in human SZ95 sebocytes via the AMPK signaling pathways in vitro	13
Advances in gene therapy and their application to skin diseases: A review	13
Contribution to the peripheral vasculopathy and endothelial cell dysfunction by CXCL4 in Systemic Sclerosis	13
Current topics in Epidermolysis bullosa: Pathophysiology and therapeutic challenges	12
Racial differences in dysregulation of the renin-angiotensin-aldosterone system in patients with prurigo nodularis	12
Effectiveness of brodalumab in achieving treatment satisfaction for patients with plaque psoriasis: The ProLOGUE study	12
Matrin-3 plays an important role in cell cycle and apoptosis for survival in malignant melanoma	12
Fingolimod ameliorates imiquimod-induced psoriasiform dermatitis by sequestrating interleukin-17-producing ?d T cells in secondary lymph nodes	12
Accelerated human epidermal turnover driven by increased hyaluronan production	11
Imiquimod-induced ROS production causes lysosomal membrane permeabilization and activates caspase-8-mediated apoptosis in skin cancer cells	11
Scientific and clinical developments in Merkel cell carcinoma: A polyomavirus-driven, often-lethal skin cancer	11
The stratum corneum transcriptome in atopic dermatitis can be assessed by tape stripping	11
Multi-omics approach identifies PI3 as a biomarker for disease severity and hyper-keratinization in psoriasis	11
Cathepsin B/NLRP3/GSDMD axis-mediated macrophage pyroptosis induces inflammation and fibrosis in systemic sclerosis	11
Aberrant serine protease activities in atopic dermatitis	11
Role of YAP-related T cell imbalance and epidermal keratinocyte dysfunction in the pathogenesis of atopic dermatitis	11
Blockade of the IL-17 signaling pathway increased susceptibility of psoriasis patients to superficial fungal infections	10
Transcriptome profiling in psoriasis: NB-UVB treatment-associated transcriptional changes and modulation of autoinflammation in perilesional skin in early-phase disease	10
Induced skin aging by blue-light irradiation in human skin fibroblasts via TGF-β, JNK and EGFR pathways	10
Age-related elevation of HGF is driven by the reduction of fibroblast size in a YAP/TAZ/CCN2 axis-dependent manner	10
Aberrant recruitment of leukocytes defines poor wound healing in patients with recessive dystrophic epidermolysis bullosa	10
Downregulation of ARMC8 promotes tumorigenesis through activating Wnt/β-catenin pathway and EMT in cutaneous squamous cell carcinomas	10
E3 ubiquitin ligase Trim33 ubiquitylates Annexin A2 to promote NF-κB induced skin inflammation in psoriasis	10
Ultraviolet irradiation-induced inhibition of histone deacetylase 4 increases the expression of matrix metalloproteinase-1 but decreases that of type I procollagen via activating JNK in human dermal f	10
Mechanical stretch-induced ATP release from keratinocytes triggers Koebner phenomenon in psoriasis	10
CXCL17-mediated downregulation of type I collagen via MMP1 and miR-29 in skin fibroblasts possibly contributes to the fibrosis in systemic sclerosis	9
Pathological functions of granzyme B in inflammatory skin diseases	9
The role of HMGB1 in inflammatory skin diseases	9
The nerve injuries attenuate the persistence of psoriatic lesions	9
EGR1/NOX4 pathway regulates oxidative stress and further facilitates fibrosis progression in keloids responses to TGF-β1	9
Genetic predisposition to bullous pemphigoid	9
Adiponectin-derived pentapeptide ameliorates psoriasiform skin inflammation by suppressing IL-17 production in γδT cells	9
Kaempferol therapy improved MC903 induced-atopic dermatitis in a mouse by suppressing TSLP, oxidative stress, and type 2 inflammation	9
Liquid biopsy-based analysis by ddPCR and CAPP-Seq in melanoma patients	8
Clinical and laboratory parameters predicting cancer in dermatomyositis patients with anti-TIF1γ antibodies	8

The temperature-sensitive receptors TRPV4 and TRPM8 have important roles in the pruritus of rosacea	8
TRPA1 promotes melanosome phagocytosis in keratinocytes via PAR-2/CYLD axis	8
Serum lactate dehydrogenase level as a possible predictor of treatment preference in psoriasis	8
Loss of FAM83H promotes cell migration and invasion in cutaneous squamous cell carcinoma via impaired keratin distribution	8
Circular RNA circ_0079593 enhances malignant melanoma progression by the regulation of the miR-573/ABHD2 axis	8
Time kinetics of cyclobutane pyrimidine dimer formation by narrowband and broadband UVB irradiation	8
Early onset female pattern hair loss: A case–control study for analyzing clinical features and genetic variants	8
Epidermal CD8+CD103+ skin resident memory T cells in psoriasis plaques are reduced in number but remain in the basement membrane zone after topical application of corticosteroid and vitamin D3	7
Abnormal inflammatory traits and downregulated caveolin-1 expression in monocytes of psoriasis patients may be associated with psoriatic inflammation and atherosclerosis	7
Targeting the elevated IFN-γ in vitiligo patients by human anti- IFN-γ monoclonal antibody hampers direct cytotoxicity in melanocyte	7
Ceramide profiling of stratum corneum in Sjögren–Larsson syndrome	7
Cycloastragenol exerts protective effects against UVB irradiation in human dermal fibroblasts and HaCaT keratinocytes	7
PDE4 inhibition by difamilast regulates filaggrin and loricrin expression via keratinocyte proline-rich protein in human keratinocytes	7
Mucopolysaccharide polysulfate promotes microvascular stabilization and barrier integrity of dermal microvascular endothelial cells via activation of the angiopoietin-1/Tie2 pathway	7
Ultra high-frequency ultrasound with seventy-MHz transducer in hair disorders: Development of a novel noninvasive diagnostic methodology	7
Tiamulin inhibits TNF-α and alleviates psoriasis-like dermatitis	7
Ethanol consumption synergistically increases ultraviolet radiation induced skin damage and immune dysfunction	7
Possible suppressive effects of baricitinib on serum IL-22 levels in atopic dermatitis	7
Tertiary lymphoid structures correlate with better prognosis in cutaneous angiosarcoma	7
Decreased mitochondrial function in UVA-irradiated dermal fibroblasts causes the insufficient formation of type I collagen and fibrillin-1 fibers	6
TGFβ activating integrins β6 and β8 are dysregulated in inflammatory skin disease and cutaneous melanoma	6
Understanding the systemic burden of disease in hidradenitis suppurativa from plasma lipidomic analysis	6
Chemical induced pathognomonic features observed in human vitiligo are mediated through miR-2909 RNomics pathway	6
Vascular morphology in facial solar lentigo assessed by optical coherence tomography angiography	6
Integrative multi-omic analysis of radiation-induced skin injury reveals the alteration of fatty acid metabolism in early response of ionizing radiation	6
Induction of alopecia areata in C3H/HeJ mice using cryopreserved lymphocytes	6
Benvitimod inhibits MCM6-meditated proliferation of keratinocytes by regulating the JAK/STAT3 pathway	6
Long non-coding RNA NEAT1 functions as a competing endogenous RNA to regulate S100A9 expression by sponging miR-196a-5p in rosacea	6
ABCB6 knockdown suppresses melanogenesis through the GSK3-β/β-catenin signaling axis in human melanoma and melanocyte cell lines	6
AZD-9056, a P2X7 receptor inhibitor, suppresses ATP-induced melanogenesis	6
Identification and quantification of senescent cell types by lamin B1 and HMGB1 in Actinic keratosis lesions	6
Photo-aging evaluation - In vitro biological endpoints combined with collagen density assessment with multi-photon microscopy	6
DNA methylation markers in peripheral blood for psoriatic arthritis	6
A new susceptibility index to predict the risk of severe herpes zoster-associated pain: A Japanese regional population-based cohort study, the Shizuoka study	6
Bone morphogenetic protein-7 inhibits endothelial-to-mesenchymal transition in primary human umbilical vein endothelial cells and mouse model of systemic sclerosis via Akt/mTOR/p70S6K pathway	5
MiR-155 inhibits TP53INP1 expression leading to enhanced glycolysis of psoriatic mesenchymal stem cells	5
The oral microbial composition and diversity affect the clinical course of palmoplantar pustulosis patients after dental focal infection treatment	5
New fluorescent three-dimensional and deep-imaging technique confirms a direct relationship between the acrosyringium and vesicles/pustules of palmoplantar pustulosis	5
Intracellular oxidative stress induced by calcium influx initiates the activation of phagocytosis in keratinocytes accumulating at S-phase of the cell cycle after UVB irradiation	5
Impaired production of the skin barrier lipid acylceramide by CYP4F22 ichthyosis mutations	5
Podocarpusflavone A inhibits cell growth of skin cutaneous melanoma by suppressing STAT3 signaling	5
Acetylcholine-induced whealing in cholinergic urticaria – What does it tell us?	5
Polycyclic aromatic hydrocarbons regulate the pigmentation pathway and induce DNA damage responses in keratinocytes, a process driven by systemic immunity	5
Altered T cell subpopulations and serum anti-TYRP2 and tyrosinase antibodies in the acute and chronic phase of alopecia areata in the C3H/HeJ mouse model	5
Phosphodiesterase-4 inhibitors reduce the expression of proinflammatory mediators by human epidermal keratinocytes independent of intracellular cAMP elevation	5
Identification of genetic mutations of cutaneous squamous cell carcinoma using whole exome sequencing in non-Caucasian population	5
Effect of universal varicella vaccination and behavioral changes against coronavirus disease 2019 pandemic on the incidence of herpes zoster	5
Risk factors for sepsis and effects of pretreatment with systemic steroid therapy for underlying condition in SJS/TEN patients: Results of a nationwide cross-sectional survey in 489 Japanese patients	5
Investigation of the keratinocyte transcriptome altered in high-glucose environment: An in-vitro model system for precision medicine	5
The human vermilion surface contains a rich amount of cholesterol sulfate than the skin	5
The regional distribution of melanosomes in the epidermis affords a localized intensive photoprotection for basal keratinocyte stem cells	5
Roflumilast enhances the melanogenesis and attenuates oxidative stress-triggered damage in melanocytes	5
Analyzing the relationship between the efficacy of first-line immune checkpoint inhibitors and cumulative sun damage in Japanese patients with advanced BRAF wild-type nonacral cutaneous melanoma: A re	5
IGFBP-7 secreted by adipose-derived stem cells inhibits keloid formation via the BRAF/MEK/ERK signaling pathway	5
SPARC promotes fibroblast proliferation, migration, and collagen production in keloids by inactivation of p53	5
MicroRNA-486–3p promotes the proliferation and metastasis of cutaneous squamous cell carcinoma by suppressing flotillin-2	5
Updated allele frequencies of SERPINB7 founder mutations in Asian patients with Nagashima-type palmoplantar keratosis/keratoderma	5
Alopecia areata: What’s new in the epidemiology, comorbidities, and pathogenesis?	5
Chromatin dynamics and epigenetics in skin stress adaptation	5
LncRNA-ZNF252P-AS1/miR-15b-5p promotes the proliferation of keloid fibroblast by regulating the BTF3-STAT3 signaling pathway	5